Publications by authors named "Pierre-Antoine Defossez"

42Publications

Staying true to yourself: mechanisms of DNA methylation maintenance in mammals.

Nucleic Acids Res 2020 Dec 9. Epub 2020 Dec 9.

Epigenetics and Cell Fate Centre, UMR7216 CNRS, Université de Paris, F-75013 Paris, France.

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December 2020

Reading DNA Modifications.

J Mol Biol 2020 Feb 8. Epub 2020 Feb 8.

CNRS/University of Paris, France.

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February 2020

Lysine Methylation Regulators Moonlighting outside the Epigenome.

Mol Cell 2019 09;75(6):1092-1101

Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address:

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September 2019

Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.

Structure 2019 03 10;27(3):485-496.e7. Epub 2019 Jan 10.

Graduate School of Medical Life Science, Yokohama City University, Yokohama 230-0045, Japan; JST, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan. Electronic address:

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March 2019

Mechanisms of DNA Methyltransferase Recruitment in Mammals.

Genes (Basel) 2018 Dec 10;9(12). Epub 2018 Dec 10.

Epigenetics and Cell Fate, UMR7216 CNRS, University Paris Diderot, Sorbonne Paris Cité, 75013 Paris, France.

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December 2018

The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling.

Aging Cell 2018 Dec 14;17(6):e12831. Epub 2018 Sep 14.

Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.

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December 2018

[Unexpected roles for a methyl-binding protein in cancer].

Med Sci (Paris) 2017 Aug-Sep;33(8-9):714-716. Epub 2017 Sep 18.

Équipe « Dynamique de la méthylation de l'ADN des génomes eucaryotes », Centre épigénétique et destin cellulaire, UMR7216 CNRS, université Paris Diderot, université Sorbonne Paris Cité (USPC), 35, rue Hélène Brion, 75205 Paris Cedex 13, France.

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April 2019

MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis.

Nucleic Acids Res 2016 Oct 14;44(18):8621-8640. Epub 2016 Jun 14.

Institut Cochin, Université Paris-Descartes, Centre National de la Recherche Scientifique (CNRS), UMR 8104, Paris, France Institut National de la Santé et de la Recherche Médicale (INSERM) U1016, Paris, France

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October 2016

The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability.

Cell Rep 2014 Apr 13;7(2):575-587. Epub 2014 Apr 13.

Epigenetics and Cell Fate, University Paris Diderot, Sorbonne Paris Cité, UMR 7216 CNRS, 75013 Paris, France. Electronic address:

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April 2014

MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress.

Epigenetics 2014 Apr 16;9(4):546-56. Epub 2014 Jan 16.

Université Paris Diderot; Sorbonne Paris Cité; Epigenetics and Cell Fate; UMR 7216 CNRS; Paris, France.

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April 2014

[Epigenetic regulation in neuronal differentiation and brain function].

Biol Aujourdhui 2013 23;207(1):1-17. Epub 2013 May 23.

Unité d'Épigénétique et Destin Cellulaire, CNRS UMR7216, Université Paris Diderot 35, rue Hélène Brion, 75205 Paris Cedex 13, France.

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January 2014

On how mammalian transcription factors recognize methylated DNA.

Epigenetics 2013 Feb 16;8(2):131-7. Epub 2013 Jan 16.

Department of Chemistry, University of Utah, Salt Lake City, UT, USA.

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February 2013

The role of methyl-binding proteins in chromatin organization and epigenome maintenance.

Brief Funct Genomics 2012 May 19;11(3):251-64. Epub 2011 Dec 19.

Institut National du Cancer (INCa), CNRS UMR7216/Université Paris Diderot, Paris, France.

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May 2012

Biological functions of methyl-CpG-binding proteins.

Prog Mol Biol Transl Sci 2011 ;101:377-98

CNRS UMR7216, Université Paris 7, Paris Cedex 13, France.

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August 2011

Mammalian methyl-binding proteins: what might they do?

Bioessays 2010 Dec 30;32(12):1025-32. Epub 2010 Sep 30.

CNRS UMR7216, Université Paris Diderot, Paris, France.

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December 2010

Sequence-specific recognition of methylated DNA by human zinc-finger proteins.

Nucleic Acids Res 2010 Aug 19;38(15):5015-22. Epub 2010 Apr 19.

CNRS UMR7216, Université Paris-Diderot, Paris, France.

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August 2010

Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes.

Int J Dev Biol 2009 ;53(2-3):323-34

CNRS UMR 218, Institut Curie, Paris, France.

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September 2009

[Master and servant: epigenetic deregulations as a cause and a consequence of cancer].

Med Sci (Paris) 2008 Aug-Sep;24(8-9):725-30

New England Biolabs, 240 County Road, Ipswich, MA 01938, Etats-Unis.

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December 2008

The cell biology of DNA methylation in mammals.

Biochim Biophys Acta 2008 Nov 28;1783(11):2167-73. Epub 2008 Jul 28.

Center BioEngineering, Russian Academy of Sciences, Prospekt 60-let Oktyabrya 7-1, 117312 Moscow, Russia.

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November 2008

Assessment of sera for chromatin-immunoprecipitation.

Biotechniques 2008 Jan;44(1):66, 68

Centre National de la Recherche Scientifique, Paris, France.

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January 2008

Born to bind: the BTB protein-protein interaction domain.

Bioessays 2006 Dec;28(12):1194-202

CNRS UMR218, Institut Curie, Section Recherche, Paris, France.

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December 2006

Using reverse electrophoretic mobility shift assay to measure and compare protein-DNA binding affinities.

Anal Biochem 2006 Oct 4;357(1):156-8. Epub 2006 Aug 4.

CNRS UMR218, Institut Curie, Section recherche, 75248 Paris Cedex 05, France.

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October 2006

[Epigenetics and cancer].

Bull Cancer 2006 Apr;93(4):343-7

CNRS UMR218, Institut Curie, Section Recherche, 26 rue d'Ulm, 75248 Paris Cedex 05.

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April 2006

Histone H1 of Saccharomyces cerevisiae inhibits transcriptional silencing.

Genetics 2006 Jun 2;173(2):579-87. Epub 2006 Apr 2.

Section Recherche, Institut Curie, CNRS UMR218, Paris, France.

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June 2006

The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso.

J Biol Chem 2005 Dec 17;280(52):43017-23. Epub 2005 Oct 17.

CNRS UMR5161, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France.

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December 2005

A methyltransferase targeting assay reveals silencer-telomere interactions in budding yeast.

Mol Cell Biol 2003 Mar;23(5):1498-508

Laboratoire de Biologie Moléculaire de la Cellule, UMR5665, Centre National de la Recherche Scientifique, Ecole Normale Supérieure de Lyon, 69364 Lyon Cedex 07, France.

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March 2003

The vertebrate protein CTCF functions as an insulator in Saccharomyces cerevisiae.

Nucleic Acids Res 2002 Dec;30(23):5136-41

CNRS UMR 5665, Ecole Normale Supérieure de Lyon, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.

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December 2002

General regulatory factors (GRFs) as genome partitioners.

J Biol Chem 2002 Nov 27;277(44):41736-43. Epub 2002 Aug 27.

CNRS/ENSL 5665, Ecole Normale Supérieure de Lyon, 46 Allée d'Italie, France.

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November 2002