Pierre de la Grange

Pierre de la Grange

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Pierre de la Grange

Publications by authors named "Pierre de la Grange"

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Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization.

Nucleic Acids Res 2020 Jan;48(2):633-645

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Heart, Rome 00168, Italy.

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http://dx.doi.org/10.1093/nar/gkz1117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954450PMC
January 2020

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.

Nat Commun 2020 Jan 10;11(1):198. Epub 2020 Jan 10.

Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France.

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http://dx.doi.org/10.1038/s41467-019-14090-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954203PMC
January 2020

An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse.

Sci Transl Med 2019 Nov;11(517)

Sorbonne Université, Centre de Recherche en Myologie, UM76, INSERM U974, Institut de Myologie, F-75013, Paris, France.

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http://dx.doi.org/10.1126/scitranslmed.aaw1131DOI Listing
November 2019

Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression.

Ann Clin Transl Neurol 2019 09 10;6(9):1681-1695. Epub 2019 Aug 10.

UMR 1078 Genetics, Functional Genomics and Biotechnology, Inserm, Université de Brest, EFS, CHU de Brest, Brest, France.

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http://dx.doi.org/10.1002/acn3.50861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764628PMC
September 2019

Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins.

Stem Cell Reports 2019 04 21;12(4):831-844. Epub 2019 Mar 21.

Institut Curie, PSL Research University, CNRS, UMR144, 26 Rue d'Ulm, 75005 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, 75005 Paris, France; Inserm, Paris, 75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450809PMC
April 2019

Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation.

Cell Rep 2019 03;26(11):2929-2941.e5

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Hearth, 00168 Rome, Italy; IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.058DOI Listing
March 2019

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling.

Breast Cancer Res 2019 01 25;21(1):13. Epub 2019 Jan 25.

Institut Curie, PSL Research University, CNRS, UMR144, 26 rue d'Ulm, F-75005, Paris, France.

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http://dx.doi.org/10.1186/s13058-019-1101-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346556PMC
January 2019

Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.

Stem Cell Reports 2018 11 25;11(5):1075-1091. Epub 2018 Oct 25.

CNRS UMR7622/IBPS, Paris, France; Université Pierre et Marie Curie, Sorbonne Universités, Paris, France; INSERM UMR_S1131, Hôpital Saint Louis, Paris, France; IUH, Université Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183042
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http://dx.doi.org/10.1016/j.stemcr.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234961PMC
November 2018

[Neurotrophic factors for motor neurons: an à la carte menu].

Med Sci (Paris) 2017 Oct 10;33(10):835-839. Epub 2017 Oct 10.

Institut de neurosciences de la Timone, UMR 7289 CNRS et Aix-Marseille Université, 27, boulevard Jean Moulin, 13005 Marseille, France.

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http://dx.doi.org/10.1051/medsci/20173310008DOI Listing
October 2017

Alternative splicing of CNOT7 diversifies CCR4-NOT functions.

Nucleic Acids Res 2017 Aug;45(14):8508-8523

Univ. Lyon, Université Lyon 1, Inserm U1052, CNRS UMR5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon 69008, France.

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http://dx.doi.org/10.1093/nar/gkx506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737658PMC
August 2017

Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.

J Hepatol 2017 05 28;66(5):930-941. Epub 2016 Dec 28.

INSERM, U1149, Centre de Recherche sur l'Inflammation (CRI), Clichy and Paris, France; UMR S_1149, Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Laboratoire d'Excellence Inflamex, ComUE Sorbonne Paris Cité, Paris, France; Département Hospitalo-Universitaire (DHU) UNITY, Service d'Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.12.008DOI Listing
May 2017

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Dev Cell 2017 04 30;41(1):82-93.e4. Epub 2017 Mar 30.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy; Laboratories of Neuroembryology, Fondazione Santa Lucia IRCCS, 00143 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392497PMC
April 2017

Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.

Proc Natl Acad Sci U S A 2017 03 7;114(12):E2486-E2493. Epub 2017 Mar 7.

Institut de Neurosciences de la Timone, UMR 7289 CNRS, Aix-Marseille University, 13005 Marseille, France;

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http://dx.doi.org/10.1073/pnas.1615372114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373341PMC
March 2017

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.

Nucleic Acids Res 2016 12 9;44(22):10929-10945. Epub 2016 Aug 9.

Sorbonne Universités, UPMC Univ Paris 06, Centre de Recherche en Myologie, INSERM UMRS974, CNRS FRE3617, Institut de Myologie, 47 bd de l'Hôpital, 75013 Paris, France

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http://dx.doi.org/10.1093/nar/gkw703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159528PMC
December 2016

Germline and somatic mutations in the gene in focal cortical dysplasia and epilepsy.

Neurol Genet 2016 Dec 31;2(6):e118. Epub 2016 Oct 31.

The Danish Epilepsy Centre Filadelfia (R.S.M., G.R.), Dianalund, Denmark; Institute for Regional Health Services (R.S.M.), University of Southern Denmark, Odense; Sorbonne Universités (S.W., E.M., V.L., E.L., S.B.), UPMC Univ Paris 06 UMR S 1127, Inserm U1127, CNRS UMR 7225, AP-HP, Institut du cerveau et la moelle (ICM)-Hôpital Pitié-Salpêtrière, Paris, France; Epilepsy Unit (S.W., V.L.), AP-HP Groupe hospitalier Pitié-Salpêtrière, Paris, France; Neurogenetics Group (S.W.), VIB-Department of Molecular Genetics; Laboratory of Neurogenetics (S.W.), Institute Born-Bunge, University of Antwerp, Belgium; Department of Neurology (S.W.), University Hospital Antwerp, Belgium; Department of Pediatric Neurosurgery (M.C., S.F.-S., G.D.), Fondation Rothschild, Paris, France; Université Paris Sorbonne Cité (V.T.), INSERM UMR-S1147 MEPPOT, CNRS SNC5014, Centre Universitaire des Saints-Pères, Paris, France; Department of Neurology (E.M.B.), University of Alabama at Birmingham; HudsonAlpha Institute for Biotechnology (S.M.H., J.W.P., K.M.B., G.M.C.), Huntsville, AL; Pediatric Neurology, Neurogenetics and Neurobiology Unit and Laboratories (D.M., V.C., R.G.), Neuroscience Department, A Meyer Children's Hospital, University of Florence, Florence, Italy; Genosplice (P.d.l.G.), Institut du Cerveau et de la Moelle épinière, ICM, Paris, France; Amplexa Genetics (L.H.G.L.), Odense, Denmark; Department of Genetics and Cytogenetics (E.L., S.B.), AP-HP Groupe hospitalier Pitié-Salpêtrière, Paris, France; and University of Copenhagen (G.R.), Denmark.

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http://dx.doi.org/10.1212/NXG.0000000000000118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089441PMC
December 2016

[Deregulation of pre-messenger RNA splicing and rare diseases].

Med Sci (Paris) 2016 Dec 3;32(12):1111-1119. Epub 2017 Jan 3.

GenoSplice technology, iPEPS - ICM, Hôpital Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1051/medsci/20163212015DOI Listing
December 2016

Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.

Mol Neurodegener 2016 06 9;11(1):43. Epub 2016 Jun 9.

Institut de Neurosciences de la Timone, UMR 7289, Centre National de la Recherche Scientifique (CNRS) and Aix-Marseille Université, 27 bd Jean Moulin, 13005 Marseille, France.

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http://dx.doi.org/10.1186/s13024-016-0111-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899909PMC
June 2016

Molecular analyses of juvenile granulosa cell tumors bearing AKT1 mutations provide insights into tumor biology and therapeutic leads.

Hum Mol Genet 2015 Dec 11;24(23):6687-98. Epub 2015 Sep 11.

Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France,

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http://dx.doi.org/10.1093/hmg/ddv373DOI Listing
December 2015

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.

Biochim Biophys Acta 2015 Dec 26;1849(12):1398-410. Epub 2015 Oct 26.

Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center - Università degli Studi di Milano, Milan 20122, Italy; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2015.10.015DOI Listing
December 2015

SNORD116 and SNORD115 change expression of multiple genes and modify each other's activity.

Gene 2015 Nov 26;572(2):266-73. Epub 2015 Jul 26.

Department of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586535PMC
November 2015

DUSP4-mediated accelerated T-cell senescence in idiopathic CD4 lymphopenia.

Blood 2015 Apr 2;125(16):2507-18. Epub 2015 Mar 2.

Université Paris-Sud, Laboratoire "Chemokines and Immunopathology," Unité Mixte de Recherche S996, Clamart, France; INSERM, Laboratory of Excellence in Research on Medication and Innovative Therapeutics, Clamart, France;

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http://dx.doi.org/10.1182/blood-2014-08-598565DOI Listing
April 2015

A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer.

PLoS One 2014 6;9(2):e87761. Epub 2014 Feb 6.

Institut National de la Santé Et de la Recherche Médicale, Unité Mixte de Recherche 1078, Université de Bretagne Occidentale, Structure Fédérative de Recherche ScInBioS, Faculté de Médecine, Brest, France ; Centre Hospitalier Régional Universitaire de Brest, Brest, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087761PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916340PMC
January 2015

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.

Nucleic Acids Res 2014 Dec 6;42(21):13194-205. Epub 2014 Nov 6.

Institut Curie, Centre de Recherche, F-75248 Paris, France CNRS, UMR3244, F-75248 Paris, France UPMC, F-75248 Paris, France.

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http://dx.doi.org/10.1093/nar/gku1101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245956PMC
December 2014

Valproic acid causes proteasomal degradation of DICER and influences miRNA expression.

PLoS One 2013 17;8(12):e82895. Epub 2013 Dec 17.

Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866160PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082895PLOS
October 2014

Sudemycin E influences alternative splicing and changes chromatin modifications.

Nucleic Acids Res 2014 Apr 11;42(8):4947-61. Epub 2014 Mar 11.

Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY 40536, USA, Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA and GenoSplice Technology, Hôpital Saint-Louis, Av Claude Vellefaux, 75010 Paris, France.

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http://dx.doi.org/10.1093/nar/gku151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005683PMC
April 2014

Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.

Biochim Biophys Acta 2013 Aug 29;1832(8):1129-35. Epub 2013 Mar 29.

Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, 741 South Limestone, Lexington, KY 40536-0509, USA.

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http://dx.doi.org/10.1016/j.bbadis.2013.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679306PMC
August 2013

Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.

PLoS One 2012 17;7(12):e51266. Epub 2012 Dec 17.

Department of Neurology, University of Kentucky, Lexington, Kentucky, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051266PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524136PMC
June 2013

Molecular characterization of a patient presumed to have prader-willi syndrome.

Clin Med Insights Case Rep 2013 5;6:79-86. Epub 2013 May 5.

University of Kentucky, Department of Molecular and Cellular Biochemistry, South Limestone, Lexington, KY.

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http://dx.doi.org/10.4137/CCRep.S11510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656643PMC
May 2013

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.

Nucleic Acids Res 2013 Apr 7;41(6):3819-32. Epub 2013 Feb 7.

Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1093/nar/gkt063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616728PMC
April 2013

Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.

J Cell Sci 2012 Oct 5;125(Pt 19):4475-86. Epub 2012 Jul 5.

CNRS UMR7212, INSERM U944, Université Paris Diderot, Institut d'Hématologie, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France.

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http://dx.doi.org/10.1242/jcs.099879DOI Listing
October 2012

Sperm transcriptome profiling in oligozoospermia.

J Assist Reprod Genet 2012 Jan 12;29(1):3-10. Epub 2011 Oct 12.

Advanced Technology Laboratory, ZA de l'Agiot 4 rue Louis Lormand, 78320, La Verrière, Paris, France.

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http://dx.doi.org/10.1007/s10815-011-9644-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252406PMC
January 2012

Splicing factor and exon profiling across human tissues.

Nucleic Acids Res 2010 May 27;38(9):2825-38. Epub 2010 Jan 27.

GenoSplice technology, Centre Hayem, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75010, Paris, France.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875023PMC
May 2010

The YTH domain is a novel RNA binding domain.

J Biol Chem 2010 May 18;285(19):14701-10. Epub 2010 Feb 18.

Institute for Biochemistry, Universität Erlangen-Nuremberg, Fahrstrasse 17, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1074/jbc.M110.104711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863249PMC
May 2010

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

Cancer Res 2010 May 20;70(9):3760-70. Epub 2010 Apr 20.

Institut National de la Sante et de la Recherche Medicale, U590, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3988DOI Listing
May 2010

Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.

Mol Cell Biol 2007 Oct 20;27(20):7315-33. Epub 2007 Aug 20.

INSERM U685, Equipe AVENIR, Hopital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France.

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http://dx.doi.org/10.1128/MCB.00272-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168895PMC
October 2007

ASEtrap: a biological method for speeding up the exploration of spliceomes.

Genome Res 2006 Jun 8;16(6):776-86. Epub 2006 May 8.

Genoscope-Centre National de Séquençage and Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR)-8030, 91000 Evry, France.

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http://dx.doi.org/10.1101/gr.5063306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479860PMC
June 2006

FAST DB: a website resource for the study of the expression regulation of human gene products.

Nucleic Acids Res 2005 28;33(13):4276-84. Epub 2005 Jul 28.

INSERM U685/AVENIR, Centre G. Hayem, Institut Universitaire d'Hématologiem, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010 Paris, France.

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http://dx.doi.org/10.1093/nar/gki738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181862PMC
August 2005