Publications by authors named "Pierre de la Grange"

69Publications

Prognostic impact of cancer stem cell markers and in colorectal cancer.

Am J Transl Res 2020 15;12(9):5797-5807. Epub 2020 Sep 15.

INSERM UMR 1078, Université de Brest 22 Avenue Camille Desmoulins, 29238 Brest, France.

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September 2020

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.

Nat Commun 2020 01 10;11(1):198. Epub 2020 Jan 10.

Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France.

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January 2020

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization.

Nucleic Acids Res 2020 01;48(2):633-645

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Heart, Rome 00168, Italy.

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January 2020

Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression.

Ann Clin Transl Neurol 2019 09 10;6(9):1681-1695. Epub 2019 Aug 10.

UMR 1078 Genetics, Functional Genomics and Biotechnology, Inserm, Université de Brest, EFS, CHU de Brest, Brest, France.

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September 2019

Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins.

Stem Cell Reports 2019 04 21;12(4):831-844. Epub 2019 Mar 21.

Institut Curie, PSL Research University, CNRS, UMR144, 26 Rue d'Ulm, 75005 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, 75005 Paris, France; Inserm, Paris, 75013 Paris, France. Electronic address:

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April 2019

Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation.

Cell Rep 2019 03;26(11):2929-2941.e5

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Hearth, 00168 Rome, Italy; IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. Electronic address:

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March 2019

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling.

Breast Cancer Res 2019 01 25;21(1):13. Epub 2019 Jan 25.

Institut Curie, PSL Research University, CNRS, UMR144, 26 rue d'Ulm, F-75005, Paris, France.

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January 2019

Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.

Stem Cell Reports 2018 11 25;11(5):1075-1091. Epub 2018 Oct 25.

CNRS UMR7622/IBPS, Paris, France; Université Pierre et Marie Curie, Sorbonne Universités, Paris, France; INSERM UMR_S1131, Hôpital Saint Louis, Paris, France; IUH, Université Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:

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November 2018

[Neurotrophic factors for motor neurons: an à la carte menu].

Med Sci (Paris) 2017 Oct 10;33(10):835-839. Epub 2017 Oct 10.

Institut de neurosciences de la Timone, UMR 7289 CNRS et Aix-Marseille Université, 27, boulevard Jean Moulin, 13005 Marseille, France.

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October 2017

Alternative splicing of CNOT7 diversifies CCR4-NOT functions.

Nucleic Acids Res 2017 Aug;45(14):8508-8523

Univ. Lyon, Université Lyon 1, Inserm U1052, CNRS UMR5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon 69008, France.

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August 2017

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Dev Cell 2017 04 30;41(1):82-93.e4. Epub 2017 Mar 30.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy; Laboratories of Neuroembryology, Fondazione Santa Lucia IRCCS, 00143 Rome, Italy. Electronic address:

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April 2017

Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.

Proc Natl Acad Sci U S A 2017 03 7;114(12):E2486-E2493. Epub 2017 Mar 7.

Institut de Neurosciences de la Timone, UMR 7289 CNRS, Aix-Marseille University, 13005 Marseille, France;

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March 2017

[Deregulation of pre-messenger RNA splicing and rare diseases].

Med Sci (Paris) 2016 Dec 3;32(12):1111-1119. Epub 2017 Jan 3.

GenoSplice technology, iPEPS - ICM, Hôpital Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France.

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December 2016

Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.

J Hepatol 2017 05 28;66(5):930-941. Epub 2016 Dec 28.

INSERM, U1149, Centre de Recherche sur l'Inflammation (CRI), Clichy and Paris, France; UMR S_1149, Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Laboratoire d'Excellence Inflamex, ComUE Sorbonne Paris Cité, Paris, France; Département Hospitalo-Universitaire (DHU) UNITY, Service d'Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France. Electronic address:

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May 2017

Germline and somatic mutations in the gene in focal cortical dysplasia and epilepsy.

Neurol Genet 2016 Dec 31;2(6):e118. Epub 2016 Oct 31.

The Danish Epilepsy Centre Filadelfia (R.S.M., G.R.), Dianalund, Denmark; Institute for Regional Health Services (R.S.M.), University of Southern Denmark, Odense; Sorbonne Universités (S.W., E.M., V.L., E.L., S.B.), UPMC Univ Paris 06 UMR S 1127, Inserm U1127, CNRS UMR 7225, AP-HP, Institut du cerveau et la moelle (ICM)-Hôpital Pitié-Salpêtrière, Paris, France; Epilepsy Unit (S.W., V.L.), AP-HP Groupe hospitalier Pitié-Salpêtrière, Paris, France; Neurogenetics Group (S.W.), VIB-Department of Molecular Genetics; Laboratory of Neurogenetics (S.W.), Institute Born-Bunge, University of Antwerp, Belgium; Department of Neurology (S.W.), University Hospital Antwerp, Belgium; Department of Pediatric Neurosurgery (M.C., S.F.-S., G.D.), Fondation Rothschild, Paris, France; Université Paris Sorbonne Cité (V.T.), INSERM UMR-S1147 MEPPOT, CNRS SNC5014, Centre Universitaire des Saints-Pères, Paris, France; Department of Neurology (E.M.B.), University of Alabama at Birmingham; HudsonAlpha Institute for Biotechnology (S.M.H., J.W.P., K.M.B., G.M.C.), Huntsville, AL; Pediatric Neurology, Neurogenetics and Neurobiology Unit and Laboratories (D.M., V.C., R.G.), Neuroscience Department, A Meyer Children's Hospital, University of Florence, Florence, Italy; Genosplice (P.d.l.G.), Institut du Cerveau et de la Moelle épinière, ICM, Paris, France; Amplexa Genetics (L.H.G.L.), Odense, Denmark; Department of Genetics and Cytogenetics (E.L., S.B.), AP-HP Groupe hospitalier Pitié-Salpêtrière, Paris, France; and University of Copenhagen (G.R.), Denmark.

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December 2016

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.

Nucleic Acids Res 2016 12 9;44(22):10929-10945. Epub 2016 Aug 9.

Sorbonne Universités, UPMC Univ Paris 06, Centre de Recherche en Myologie, INSERM UMRS974, CNRS FRE3617, Institut de Myologie, 47 bd de l'Hôpital, 75013 Paris, France

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December 2016

Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.

Mol Neurodegener 2016 06 9;11(1):43. Epub 2016 Jun 9.

Institut de Neurosciences de la Timone, UMR 7289, Centre National de la Recherche Scientifique (CNRS) and Aix-Marseille Université, 27 bd Jean Moulin, 13005 Marseille, France.

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June 2016

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.

Biochim Biophys Acta 2015 Dec 26;1849(12):1398-410. Epub 2015 Oct 26.

Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center - Università degli Studi di Milano, Milan 20122, Italy; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy. Electronic address:

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December 2015

SNORD116 and SNORD115 change expression of multiple genes and modify each other's activity.

Gene 2015 Nov 26;572(2):266-73. Epub 2015 Jul 26.

Department of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, United States. Electronic address:

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November 2015

DUSP4-mediated accelerated T-cell senescence in idiopathic CD4 lymphopenia.

Blood 2015 Apr 2;125(16):2507-18. Epub 2015 Mar 2.

Université Paris-Sud, Laboratoire "Chemokines and Immunopathology," Unité Mixte de Recherche S996, Clamart, France; INSERM, Laboratory of Excellence in Research on Medication and Innovative Therapeutics, Clamart, France;

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April 2015

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.

Nucleic Acids Res 2014 Dec 6;42(21):13194-205. Epub 2014 Nov 6.

Institut Curie, Centre de Recherche, F-75248 Paris, France CNRS, UMR3244, F-75248 Paris, France UPMC, F-75248 Paris, France.

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December 2014

Sudemycin E influences alternative splicing and changes chromatin modifications.

Nucleic Acids Res 2014 Apr 11;42(8):4947-61. Epub 2014 Mar 11.

Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY 40536, USA, Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA and GenoSplice Technology, Hôpital Saint-Louis, Av Claude Vellefaux, 75010 Paris, France.

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April 2014

A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer.

PLoS One 2014 6;9(2):e87761. Epub 2014 Feb 6.

Institut National de la Santé Et de la Recherche Médicale, Unité Mixte de Recherche 1078, Université de Bretagne Occidentale, Structure Fédérative de Recherche ScInBioS, Faculté de Médecine, Brest, France ; Centre Hospitalier Régional Universitaire de Brest, Brest, France.

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January 2015

Valproic acid causes proteasomal degradation of DICER and influences miRNA expression.

PLoS One 2013 17;8(12):e82895. Epub 2013 Dec 17.

Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America.

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October 2014

Molecular characterization of a patient presumed to have prader-willi syndrome.

Clin Med Insights Case Rep 2013 5;6:79-86. Epub 2013 May 5.

University of Kentucky, Department of Molecular and Cellular Biochemistry, South Limestone, Lexington, KY.

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May 2013

Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.

Biochim Biophys Acta 2013 Aug 29;1832(8):1129-35. Epub 2013 Mar 29.

Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, 741 South Limestone, Lexington, KY 40536-0509, USA.

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August 2013

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.

Nucleic Acids Res 2013 Apr 7;41(6):3819-32. Epub 2013 Feb 7.

Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY 40536, USA.

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April 2013

Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.

PLoS One 2012 17;7(12):e51266. Epub 2012 Dec 17.

Department of Neurology, University of Kentucky, Lexington, Kentucky, United States of America.

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June 2013

Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.

J Cell Sci 2012 Oct 5;125(Pt 19):4475-86. Epub 2012 Jul 5.

CNRS UMR7212, INSERM U944, Université Paris Diderot, Institut d'Hématologie, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France.

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October 2012

Sperm transcriptome profiling in oligozoospermia.

J Assist Reprod Genet 2012 Jan 12;29(1):3-10. Epub 2011 Oct 12.

Advanced Technology Laboratory, ZA de l'Agiot 4 rue Louis Lormand, 78320, La Verrière, Paris, France.

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January 2012

Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.

PLoS One 2011 Apr 15;6(4):e18784. Epub 2011 Apr 15.

Unité Mixte de Recherche Scientifique 940, Institut National de la Santé et de la Recherche Médicale, Université Paris-Diderot Paris 7, Hôpital St Louis, Paris, France.

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April 2011

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

Cancer Res 2010 May 20;70(9):3760-70. Epub 2010 Apr 20.

Institut National de la Sante et de la Recherche Medicale, U590, Centre Léon Bérard, Lyon, France.

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May 2010

The YTH domain is a novel RNA binding domain.

J Biol Chem 2010 May 18;285(19):14701-10. Epub 2010 Feb 18.

Institute for Biochemistry, Universität Erlangen-Nuremberg, Fahrstrasse 17, 91054 Erlangen, Germany.

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May 2010

Splicing factor and exon profiling across human tissues.

Nucleic Acids Res 2010 May 27;38(9):2825-38. Epub 2010 Jan 27.

GenoSplice technology, Centre Hayem, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75010, Paris, France.

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May 2010

Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.

Mol Cell Biol 2007 Oct 20;27(20):7315-33. Epub 2007 Aug 20.

INSERM U685, Equipe AVENIR, Hopital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France.

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October 2007

ASEtrap: a biological method for speeding up the exploration of spliceomes.

Genome Res 2006 Jun 8;16(6):776-86. Epub 2006 May 8.

Genoscope-Centre National de Séquençage and Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR)-8030, 91000 Evry, France.

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June 2006

FAST DB: a website resource for the study of the expression regulation of human gene products.

Nucleic Acids Res 2005 28;33(13):4276-84. Epub 2005 Jul 28.

INSERM U685/AVENIR, Centre G. Hayem, Institut Universitaire d'Hématologiem, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010 Paris, France.

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August 2005