Pierre de la Grange

Pierre de la Grange

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Pierre de la Grange

Publications by authors named "Pierre de la Grange"

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Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization.

Authors:
Vittoria Pagliarini Ariane Jolly Pamela Bielli Valentina Di Rosa Pierre De la Grange Claudio Sette

Nucleic Acids Res 2020 Jan;48(2):633-645

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Heart, Rome 00168, Italy.

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http://dx.doi.org/10.1093/nar/gkz1117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954450PMC
January 2020

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.

Authors:
Nadjet Gacem Anthula Kavo Lisa Zerad Laurence Richard Stephane Mathis Raj P Kapur Melanie Parisot Jeanne Amiel Sylvie Dufour Pierre de la Grange Veronique Pingault Jean Michel Vallat Nadege Bondurand

Nat Commun 2020 Jan 10;11(1):198. Epub 2020 Jan 10.

Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France.

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http://dx.doi.org/10.1038/s41467-019-14090-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954203PMC
January 2020

An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse.

Authors:
Massiré Traoré Christel Gentil Chiara Benedetto Jean-Yves Hogrel Pierre De la Grange Bruno Cadot Sofia Benkhelifa-Ziyyat Laura Julien Mégane Lemaitre Arnaud Ferry France Piétri-Rouxel Sestina Falcone

Sci Transl Med 2019 Nov;11(517)

Sorbonne Université, Centre de Recherche en Myologie, UM76, INSERM U974, Institut de Myologie, F-75013, Paris, France.

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http://dx.doi.org/10.1126/scitranslmed.aaw1131DOI Listing
November 2019

SpliceLauncher: a tool for detection, annotation and relative quantification of alternative junctions from RNAseq data.

Authors:
Raphaël Leman Valentin Harter Alexandre Atkinson Grégoire Davy Antoine Rousselin Etienne Muller Laurent Castéra Fréderic Lemoine Pierre de la Grange Marine Guillaud-Bataille Dominique Vaur Sophie Krieger

Bioinformatics 2019 Oct 16. Epub 2019 Oct 16.

Laboratoire de biologie et de génétique du cancer, Centre François Baclesse, Caen, France.

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http://dx.doi.org/10.1093/bioinformatics/btz784DOI Listing
October 2019

Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression.

Authors:
LeeAnn Ramsay Marie-Lise Quillé Cyrille Orset Pierre de la Grange Estelle Rousselet Claude Férec Gérald Le Gac Emmanuelle Génin Serge Timsit

Ann Clin Transl Neurol 2019 09 10;6(9):1681-1695. Epub 2019 Aug 10.

UMR 1078 Genetics, Functional Genomics and Biotechnology, Inserm, Université de Brest, EFS, CHU de Brest, Brest, France.

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http://dx.doi.org/10.1002/acn3.50861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764628PMC
September 2019

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice.

Authors:
Sarah Lévesque Julie Le Naour Federico Pietrocola Juliette Paillet Margerie Kremer Francesca Castoldi Elisa E Baracco Yan Wang Erika Vacchelli Gautier Stoll Ariane Jolly Pierre De La Grange Laurence Zitvogel Guido Kroemer Jonathan G Pol

Oncoimmunology 2019 7;8(11):e1657375. Epub 2019 Sep 7.

Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2019.1657375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791453PMC
September 2019

Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins.

Authors:
Mathilde Romagnoli Stéphanie Cagnet Aurélie Chiche Laura Bresson Sylvain Baulande Pierre de la Grange Adèle De Arcangelis Maaike Kreft Elisabeth Georges-Labouesse Arnoud Sonnenberg Marie-Ange Deugnier Karine Raymond Marina A Glukhova Marisa M Faraldo

Stem Cell Reports 2019 May;12(5):1178

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https://linkinghub.elsevier.com/retrieve/pii/S22136711193014
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http://dx.doi.org/10.1016/j.stemcr.2019.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524752PMC
May 2019

Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins.

Authors:
Mathilde Romagnoli Stéphanie Cagnet Aurélie Chiche Laura Bresson Sylvain Baulande Pierre de la Grange Adèle De Arcangelis Maaike Kreft Elisabeth Georges-Labouesse Arnoud Sonnenberg Marie-Ange Deugnier Karine Raymond Marina A Glukhova Marisa M Faraldo

Stem Cell Reports 2019 04 21;12(4):831-844. Epub 2019 Mar 21.

Institut Curie, PSL Research University, CNRS, UMR144, 26 Rue d'Ulm, 75005 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, 75005 Paris, France; Inserm, Paris, 75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450809PMC
April 2019

Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation.

Authors:
Chiara Naro Livia Pellegrini Ariane Jolly Donatella Farini Eleonora Cesari Pamela Bielli Pierre de la Grange Claudio Sette

Cell Rep 2019 03;26(11):2929-2941.e5

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Hearth, 00168 Rome, Italy; IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.058DOI Listing
March 2019

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling.

Authors:
Aurélie Chiche Amandine Di-Cicco Laura Sesma-Sanz Laura Bresson Pierre de la Grange Marina A Glukhova Marisa M Faraldo Marie-Ange Deugnier

Breast Cancer Res 2019 01 25;21(1):13. Epub 2019 Jan 25.

Institut Curie, PSL Research University, CNRS, UMR144, 26 rue d'Ulm, F-75005, Paris, France.

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http://dx.doi.org/10.1186/s13058-019-1101-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346556PMC
January 2019

Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.

Authors:
Carine Domenech Loïc Maillard Alix Rousseau Fabien Guidez Laurence Petit Marika Pla Denis Clay Fabien Guimiot Sandra Sanfilippo Sebastien Jacques Pierre de la Grange Noémie Robil Jean Soulier Michèle Souyri

Stem Cell Reports 2018 11 25;11(5):1075-1091. Epub 2018 Oct 25.

CNRS UMR7622/IBPS, Paris, France; Université Pierre et Marie Curie, Sorbonne Universités, Paris, France; INSERM UMR_S1131, Hôpital Saint Louis, Paris, France; IUH, Université Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183042
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http://dx.doi.org/10.1016/j.stemcr.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234961PMC
November 2018

The iron chelator deferasirox synergises with chemotherapy to treat triple-negative breast cancers.

Authors:
Sandrine Tury Franck Assayag Florian Bonin Sophie Chateau-Joubert Jean-Luc Servely Sophie Vacher Véronique Becette Martial Caly Audrey Rapinat David Gentien Pierre de la Grange Anne Schnitzler François Lallemand Elisabetta Marangoni Ivan Bièche Céline Callens

J Pathol 2018 09 7;246(1):103-114. Epub 2018 Aug 7.

Pharmacogenomic Unit, Genetics Department, Curie Institute, PSL Research University, Paris, France.

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http://doi.wiley.com/10.1002/path.5104
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http://dx.doi.org/10.1002/path.5104DOI Listing
September 2018

Identification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma.

Authors:
Aurélie Bruno Karim Labreche Maïlys Daniau Blandine Boisselier Guillaume Gauchotte Louis Royer-Perron Amithys Rahimian Frédéric Lemoine Pierre de la Grange Justine Guégan Franck Bielle Marc Polivka Clovis Adam David Meyronet Dominique Figarella-Branger Chiara Villa Fabrice Chrétien Sandrine Eimer Frédéric Davi Audrey Rousseau Caroline Houillier Carole Soussain Karima Mokhtari Khê Hoang-Xuan Agusti Alentorn

Neuro Oncol 2018 07;20(8):1092-1100

Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Universités, UPMC, University Paris, Institut du Cerveau et de la Moelle épinière, INSERM, CNRS UMR, Paris, France.

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http://dx.doi.org/10.1093/neuonc/noy019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280140PMC
July 2018

Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer.

Authors:
Grégoire Davy Antoine Rousselin Nicolas Goardon Laurent Castéra Valentin Harter Angelina Legros Etienne Muller Robin Fouillet Baptiste Brault Anna S Smirnova Fréderic Lemoine Pierre de la Grange Marine Guillaud-Bataille Virginie Caux-Moncoutier Claude Houdayer Françoise Bonnet Cécile Blanc-Fournier Pascaline Gaildrat Thierry Frebourg Alexandra Martins Dominique Vaur Sophie Krieger

Eur J Hum Genet 2017 10 26;25(10):1147-1154. Epub 2017 Jul 26.

Department of Cancer Biology and Genetics, CLCC François Baclesse, Normandy Centre for Genomic and Personalized Medicine, Caen, France.

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http://dx.doi.org/10.1038/ejhg.2017.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602017PMC
October 2017

[Neurotrophic factors for motor neurons: an à la carte menu].

Authors:
Alysson Alory Arnaud Jacquier David Gentien Pierre de la Grange Georg Haase

Med Sci (Paris) 2017 Oct 10;33(10):835-839. Epub 2017 Oct 10.

Institut de neurosciences de la Timone, UMR 7289 CNRS et Aix-Marseille Université, 27, boulevard Jean Moulin, 13005 Marseille, France.

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http://dx.doi.org/10.1051/medsci/20173310008DOI Listing
October 2017

Alternative splicing of CNOT7 diversifies CCR4-NOT functions.

Authors:
Clément Chapat Kamel Chettab Pierre Simonet Peng Wang Pierre De La Grange Muriel Le Romancer Laura Corbo

Nucleic Acids Res 2017 Aug;45(14):8508-8523

Univ. Lyon, Université Lyon 1, Inserm U1052, CNRS UMR5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon 69008, France.

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http://dx.doi.org/10.1093/nar/gkx506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737658PMC
August 2017

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization.

Authors:
David Vallerand Gérald Massonnet Fatima Kébir David Gentien Zofia Maciorowski Pierre De la Grange Brigitte Sigal-Zafrani Marion Richardson Sandrine Humbert Aurélie Thuleau Franck Assayag Ludmilla de Plater André Nicolas Suzy Scholl Elisabetta Marangoni Stefan Weigand Sergio Roman-Roman Ariel Savina Didier Decaudin

PLoS One 2016 7;11(7):e0157670. Epub 2016 Jul 7.

Translational Research Department, Laboratory of Preclinical Investigation, Institut Curie, PSL University, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157670PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936680PMC
July 2017

Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.

Authors:
Shvetank Sharma Jaswinder S Maras Sukanta Das Shabir Hussain Ashwani K Mishra Saggere M Shasthry Chhagan B Sharma Emmanuel Weiss Laure Elkrief Pierre-Emmanuel Rautou Hélène Gilgenkrantz Sophie Lotersztajn Valérie Paradis Pierre de la Grange Christophe Junot Richard Moreau Shiv K Sarin

Sci Rep 2017 07 28;7(1):6816. Epub 2017 Jul 28.

Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.

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http://dx.doi.org/10.1038/s41598-017-07161-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533759PMC
July 2017

Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.

Authors:
Emmanuel Weiss Pierre-Emmanuel Rautou Magali Fasseu Mikhael Giabicani Marc de Chambrun JingHong Wan Charlotte Minsart Thierry Gustot Alain Couvineau Rakhi Maiwall Margarita Hurtado-Nedelec Nathalie Pilard Didier Lebrec Dominique Valla François Durand Pierre de la Grange Renato C Monteiro Catherine Paugam-Burtz Sophie Lotersztajn Richard Moreau

J Hepatol 2017 05 28;66(5):930-941. Epub 2016 Dec 28.

INSERM, U1149, Centre de Recherche sur l'Inflammation (CRI), Clichy and Paris, France; UMR S_1149, Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Laboratoire d'Excellence Inflamex, ComUE Sorbonne Paris Cité, Paris, France; Département Hospitalo-Universitaire (DHU) UNITY, Service d'Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.12.008DOI Listing
May 2017

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Authors:
Chiara Naro Ariane Jolly Sara Di Persio Pamela Bielli Niclas Setterblad Antonio J Alberdi Elena Vicini Raffaele Geremia Pierre De la Grange Claudio Sette

Dev Cell 2017 04 30;41(1):82-93.e4. Epub 2017 Mar 30.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy; Laboratories of Neuroembryology, Fondazione Santa Lucia IRCCS, 00143 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392497PMC
April 2017

Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.

Authors:
Sébastien Schaller Dorothée Buttigieg Alysson Alory Arnaud Jacquier Marc Barad Mark Merchant David Gentien Pierre de la Grange Georg Haase

Proc Natl Acad Sci U S A 2017 03 7;114(12):E2486-E2493. Epub 2017 Mar 7.

Institut de Neurosciences de la Timone, UMR 7289 CNRS, Aix-Marseille University, 13005 Marseille, France;

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http://dx.doi.org/10.1073/pnas.1615372114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373341PMC
March 2017

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.

Authors:
Pierre Klein Martine Oloko Fanny Roth Valérie Montel Alberto Malerba Susan Jarmin Teresa Gidaro Linda Popplewell Sophie Perie Jean Lacau St Guily Pierre de la Grange Michael N Antoniou George Dickson Gillian Butler-Browne Bruno Bastide Vincent Mouly Capucine Trollet

Nucleic Acids Res 2016 12 9;44(22):10929-10945. Epub 2016 Aug 9.

Sorbonne Universités, UPMC Univ Paris 06, Centre de Recherche en Myologie, INSERM UMRS974, CNRS FRE3617, Institut de Myologie, 47 bd de l'Hôpital, 75013 Paris, France

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http://dx.doi.org/10.1093/nar/gkw703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159528PMC
December 2016

Germline and somatic mutations in the gene in focal cortical dysplasia and epilepsy.

Authors:
Rikke S Møller Sarah Weckhuysen Mathilde Chipaux Elise Marsan Valerie Taly E Martina Bebin Susan M Hiatt Jeremy W Prokop Kevin M Bowling Davide Mei Valerio Conti Pierre de la Grange Sarah Ferrand-Sorbets Georg Dorfmüller Virginie Lambrecq Line H G Larsen Eric Leguern Renzo Guerrini Guido Rubboli Gregory M Cooper Stéphanie Baulac

Neurol Genet 2016 Dec 31;2(6):e118. Epub 2016 Oct 31.

The Danish Epilepsy Centre Filadelfia (R.S.M., G.R.), Dianalund, Denmark; Institute for Regional Health Services (R.S.M.), University of Southern Denmark, Odense; Sorbonne Universités (S.W., E.M., V.L., E.L., S.B.), UPMC Univ Paris 06 UMR S 1127, Inserm U1127, CNRS UMR 7225, AP-HP, Institut du cerveau et la moelle (ICM)-Hôpital Pitié-Salpêtrière, Paris, France; Epilepsy Unit (S.W., V.L.), AP-HP Groupe hospitalier Pitié-Salpêtrière, Paris, France; Neurogenetics Group (S.W.), VIB-Department of Molecular Genetics; Laboratory of Neurogenetics (S.W.), Institute Born-Bunge, University of Antwerp, Belgium; Department of Neurology (S.W.), University Hospital Antwerp, Belgium; Department of Pediatric Neurosurgery (M.C., S.F.-S., G.D.), Fondation Rothschild, Paris, France; Université Paris Sorbonne Cité (V.T.), INSERM UMR-S1147 MEPPOT, CNRS SNC5014, Centre Universitaire des Saints-Pères, Paris, France; Department of Neurology (E.M.B.), University of Alabama at Birmingham; HudsonAlpha Institute for Biotechnology (S.M.H., J.W.P., K.M.B., G.M.C.), Huntsville, AL; Pediatric Neurology, Neurogenetics and Neurobiology Unit and Laboratories (D.M., V.C., R.G.), Neuroscience Department, A Meyer Children's Hospital, University of Florence, Florence, Italy; Genosplice (P.d.l.G.), Institut du Cerveau et de la Moelle épinière, ICM, Paris, France; Amplexa Genetics (L.H.G.L.), Odense, Denmark; Department of Genetics and Cytogenetics (E.L., S.B.), AP-HP Groupe hospitalier Pitié-Salpêtrière, Paris, France; and University of Copenhagen (G.R.), Denmark.

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http://dx.doi.org/10.1212/NXG.0000000000000118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089441PMC
December 2016

[Deregulation of pre-messenger RNA splicing and rare diseases].

Authors:
Pierre de la Grange

Med Sci (Paris) 2016 Dec 3;32(12):1111-1119. Epub 2017 Jan 3.

GenoSplice technology, iPEPS - ICM, Hôpital Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France.

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http://dx.doi.org/10.1051/medsci/20163212015DOI Listing
December 2016

Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.

Authors:
Sarah Weckhuysen Elise Marsan Virginie Lambrecq Cécile Marchal Mélanie Morin-Brureau Isabelle An-Gourfinkel Michel Baulac Martine Fohlen Christine Kallay Zetchi Margitta Seeck Pierre de la Grange Bart Dermaut Alfred Meurs Pierre Thomas Francine Chassoux Eric Leguern Fabienne Picard Stéphanie Baulac

Epilepsia 2016 06 13;57(6):994-1003. Epub 2016 May 13.

INSERM, U1127, ICM, Paris, France.

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http://dx.doi.org/10.1111/epi.13391DOI Listing
June 2016

Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.

Authors:
Sarah Bellouze Gilbert Baillat Dorothée Buttigieg Pierre de la Grange Catherine Rabouille Georg Haase

Mol Neurodegener 2016 06 9;11(1):43. Epub 2016 Jun 9.

Institut de Neurosciences de la Timone, UMR 7289, Centre National de la Recherche Scientifique (CNRS) and Aix-Marseille Université, 27 bd Jean Moulin, 13005 Marseille, France.

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http://dx.doi.org/10.1186/s13024-016-0111-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899909PMC
June 2016

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways.

Authors:
Laura Guerenne Stéphanie Beurlet Mohamed Said Petra Gorombei Carole Le Pogam Fabien Guidez Pierre de la Grange Nader Omidvar Valérie Vanneaux Ken Mills Ghulam J Mufti Laure Sarda-Mantel Maria Elena Noguera Marika Pla Pierre Fenaux Rose Ann Padua Christine Chomienne Patricia Krief

J Hematol Oncol 2016 Jan 27;9. Epub 2016 Jan 27.

Université Paris-Diderot, Sorbonne Paris Cité, Institut Universitaire d'Hématologie, Unité Mixte de Recherche (UMR-S) 1131, Paris, France.

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http://dx.doi.org/10.1186/s13045-016-0235-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728810PMC
January 2016

Molecular analyses of juvenile granulosa cell tumors bearing AKT1 mutations provide insights into tumor biology and therapeutic leads.

Authors:
Aurélie Auguste Laurianne Bessière Anne-Laure Todeschini Sandrine Caburet Sabine Sarnacki Jaime Prat Emanuela D'angelo Pierre De La Grange Olivier Ariste Fréderic Lemoine Bérangère Legois Charles Sultan Alain Zider Louise Galmiche Nicolas Kalfa Reiner A Veitia

Hum Mol Genet 2015 Dec 11;24(23):6687-98. Epub 2015 Sep 11.

Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France,

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http://dx.doi.org/10.1093/hmg/ddv373DOI Listing
December 2015

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.

Authors:
Claudia Colombrita Elisa Onesto Emanuele Buratti Pierre de la Grange Valentina Gumina Francisco E Baralle Vincenzo Silani Antonia Ratti

Biochim Biophys Acta 2015 Dec 26;1849(12):1398-410. Epub 2015 Oct 26.

Department of Pathophysiology and Transplantation, 'Dino Ferrari' Center - Università degli Studi di Milano, Milan 20122, Italy; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan 20149, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2015.10.015DOI Listing
December 2015

SNORD116 and SNORD115 change expression of multiple genes and modify each other's activity.

Authors:
Marina Falaleeva Justin Surface Manli Shen Pierre de la Grange Stefan Stamm

Gene 2015 Nov 26;572(2):266-73. Epub 2015 Jul 26.

Department of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586535PMC
November 2015

DUSP4-mediated accelerated T-cell senescence in idiopathic CD4 lymphopenia.

Authors:
Alexandre Bignon Alexis Régent Laurence Klipfel Aude Desnoyer Pierre de la Grange Valérie Martinez Olivier Lortholary Ali Dalloul Luc Mouthon Karl Balabanian

Blood 2015 Apr 2;125(16):2507-18. Epub 2015 Mar 2.

Université Paris-Sud, Laboratoire "Chemokines and Immunopathology," Unité Mixte de Recherche S996, Clamart, France; INSERM, Laboratory of Excellence in Research on Medication and Innovative Therapeutics, Clamart, France;

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http://dx.doi.org/10.1182/blood-2014-08-598565DOI Listing
April 2015

A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer.

Authors:
Marine Pesson Alain Volant Arnaud Uguen Kilian Trillet Pierre De La Grange Marc Aubry Mélanie Daoulas Michel Robaszkiewicz Gérald Le Gac Alain Morel Brigitte Simon Laurent Corcos

PLoS One 2014 6;9(2):e87761. Epub 2014 Feb 6.

Institut National de la Santé Et de la Recherche Médicale, Unité Mixte de Recherche 1078, Université de Bretagne Occidentale, Structure Fédérative de Recherche ScInBioS, Faculté de Médecine, Brest, France ; Centre Hospitalier Régional Universitaire de Brest, Brest, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087761PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916340PMC
January 2015

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.

Authors:
Nicolas Vogt Anne Gibaud Frédéric Lemoine Pierre de la Grange Michelle Debatisse Bernard Malfoy

Nucleic Acids Res 2014 Dec 6;42(21):13194-205. Epub 2014 Nov 6.

Institut Curie, Centre de Recherche, F-75248 Paris, France CNRS, UMR3244, F-75248 Paris, France UPMC, F-75248 Paris, France.

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http://dx.doi.org/10.1093/nar/gku1101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245956PMC
December 2014

Valproic acid causes proteasomal degradation of DICER and influences miRNA expression.

Authors:
Zhaiyi Zhang Paolo Convertini Manli Shen Xiu Xu Frédéric Lemoine Pierre de la Grange Douglas A Andres Stefan Stamm

PLoS One 2013 17;8(12):e82895. Epub 2013 Dec 17.

Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866160PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082895PLOS
October 2014

Acquired resistance to endocrine treatments is associated with tumor-specific molecular changes in patient-derived luminal breast cancer xenografts.

Authors:
Paul Cottu Ivan Bièche Franck Assayag Rania El Botty Sophie Chateau-Joubert Aurélie Thuleau Thomas Bagarre Benoit Albaud Audrey Rapinat David Gentien Pierre de la Grange Vonick Sibut Sophie Vacher Rana Hatem Jean-Luc Servely Jean-Jacques Fontaine Didier Decaudin Jean-Yves Pierga Sergio Roman-Roman Elisabetta Marangoni

Clin Cancer Res 2014 Aug 19;20(16):4314-25. Epub 2014 Jun 19.

Laboratory of Preclinical Investigation, Translational Research Department;

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3230DOI Listing
August 2014

Sudemycin E influences alternative splicing and changes chromatin modifications.

Authors:
Paolo Convertini Manli Shen Philip M Potter Gustavo Palacios Chandraiah Lagisetti Pierre de la Grange Craig Horbinski Yvonne N Fondufe-Mittendorf Thomas R Webb Stefan Stamm

Nucleic Acids Res 2014 Apr 11;42(8):4947-61. Epub 2014 Mar 11.

Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY 40536, USA, Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA and GenoSplice Technology, Hôpital Saint-Louis, Av Claude Vellefaux, 75010 Paris, France.

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http://dx.doi.org/10.1093/nar/gku151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005683PMC
April 2014

A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies.

Authors:
Marine Pesson Béatrice Eymin Pierre De La Grange Brigitte Simon Laurent Corcos

Mol Cancer 2014 Jan 15;13. Epub 2014 Jan 15.

UMR INSERM U1078-UBO, Equipe ECLA, Faculté de Médecine, 22 Avenue Camille Desmoulins, 29200 Brest, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899606PMC
January 2014

SF3B1 mutations are associated with alternative splicing in uveal melanoma.

Authors:
Simon J Furney Malin Pedersen David Gentien Amaury G Dumont Audrey Rapinat Laurence Desjardins Samra Turajlic Sophie Piperno-Neumann Pierre de la Grange Sergio Roman-Roman Marc-Henri Stern Richard Marais

Cancer Discov 2013 Oct 16;3(10):1122-1129. Epub 2013 Jul 16.

The Cancer Research UK Manchester Institute, Wilmslow Road, Manchester M20 4BX, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321577PMC
October 2013

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.

Authors:
Stephanie Beurlet Nader Omidvar Petra Gorombei Patricia Krief Carole Le Pogam Niclas Setterblad Pierre de la Grange Christophe Leboeuf Anne Janin Maria-Elena Noguera Florence Hervatin Laure Sarda-Mantel Marina Konopleva Michael Andreeff Andrea W Tu Alice C Fan Dean W Felsher Anthony Whetton Marika Pla Robert West Pierre Fenaux Christine Chomienne Rose Ann Padua

Blood 2013 Oct 13;122(16):2864-76. Epub 2013 Aug 13.

Institut National de la Santé et de la Recherche Médicale U940, Paris, France;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799000PMC
October 2013

CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.

Authors:
Audrey Astori Hanne Fredly Thomas Aquinas Aloysius Lars Bullinger Véronique Mansat-De Mas Pierre de la Grange François Delhommeau Karen Marie Hagen Christian Récher Isabelle Dusanter-Fourt Stian Knappskog Johan Richard Lillehaug Frédéric Pendino Øystein Bruserud

Oncotarget 2013 Sep;4(9):1438-48

Inserm, U1016, Institut Cochin, F-75014, Paris, France.

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http://dx.doi.org/10.18632/oncotarget.1195DOI Listing
September 2013

Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.

Authors:
Paolo Convertini Jiayu Zhang Pierre de la Grange Lawrence J Hayward Haining Zhu Stefan Stamm

Biochim Biophys Acta 2013 Aug 29;1832(8):1129-35. Epub 2013 Mar 29.

Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, 741 South Limestone, Lexington, KY 40536-0509, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679306PMC
August 2013

Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.

Authors:
Erming Wang Vahid Aslanzadeh Filomena Papa Haiyan Zhu Pierre de la Grange Franca Cambi

PLoS One 2012 17;7(12):e51266. Epub 2012 Dec 17.

Department of Neurology, University of Kentucky, Lexington, Kentucky, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524136PMC
June 2013

Human induced pluripotent stem cells as a tool to model a form of Leber congenital amaurosis.

Authors:
Céline Lustremant Walter Habeler Alexandra Plancheron Olivier Goureau Lydie Grenot Pierre de la Grange Isabelle Audo Emeline F Nandrot Christelle Monville

Cell Reprogram 2013 Jun 10;15(3):233-46. Epub 2013 May 10.

INSERM U861, I-STEM, AFM, Evry 91030 cedex France.

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http://dx.doi.org/10.1089/cell.2012.0076DOI Listing
June 2013

Gene- and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis.

Authors:
Sonia Gandoura Emmanuel Weiss Pierre-Emmanuel Rautou Magali Fasseu Thierry Gustot Frédéric Lemoine Margarita Hurtado-Nedelec Caroline Hego Nathalie Vadrot Laure Elkrief Philippe Lettéron Zéra Tellier Marie-Anne Pocidalo Dominique Valla Didier Lebrec André Groyer Renato C Monteiro Pierre de la Grange Richard Moreau

J Hepatol 2013 May 12;58(5):936-48. Epub 2013 Jan 12.

INSERM, U773, Centre de Recherche Biomédicale Bichat-Beaujon CRB3, Clichy and Paris, France.

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May 2013

Molecular characterization of a patient presumed to have prader-willi syndrome.

Authors:
Marina Falaleeva Carlos R Sulsona Horst R Zielke Kathleen M Currey Pierre de la Grange Vahid Aslanzadeh Daniel J Driscoll Stefan Stamm

Clin Med Insights Case Rep 2013 5;6:79-86. Epub 2013 May 5.

University of Kentucky, Department of Molecular and Cellular Biochemistry, South Limestone, Lexington, KY.

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http://dx.doi.org/10.4137/CCRep.S11510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656643PMC
May 2013

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.

Authors:
Manli Shen Stanislav Bellaousov Michael Hiller Pierre de La Grange Trevor P Creamer Orit Malina Ruth Sperling David H Mathews Peter Stoilov Stefan Stamm

Nucleic Acids Res 2013 Apr 7;41(6):3819-32. Epub 2013 Feb 7.

Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 South Limestone, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1093/nar/gkt063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616728PMC
April 2013

hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.

Authors:
Clément Chapat Chloé Kolytcheff Muriel Le Romancer Didier Auboeuf Pierre De La Grange Kamel Chettab Stéphanie Sentis Laura Corbo

EMBO J 2013 Mar 5;32(5):688-700. Epub 2013 Feb 5.

Université Lyon 1, Lyon, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594750PMC
March 2013

The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling.

Authors:
Cristovão Moreira Sousa John Russel McGuire Morgane Sonia Thion David Gentien Pierre de la Grange Sophie Tezenas du Montcel Anne Vincent-Salomon Alexandra Durr Sandrine Humbert

EMBO Mol Med 2013 Feb 9;5(2):309-25. Epub 2013 Jan 9.

Institut Curie, Paris, France; CNRS UMR 3306, Orsay, France.

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http://dx.doi.org/10.1002/emmm.201201546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569645PMC
February 2013

Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.

Authors:
Benoît Gaudineau Marjorie Fougère Frédéric Guaddachi Frédéric Lemoine Pierre de la Grange Sébastien Jauliac

J Cell Sci 2012 Oct 5;125(Pt 19):4475-86. Epub 2012 Jul 5.

CNRS UMR7212, INSERM U944, Université Paris Diderot, Institut d'Hématologie, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75475 Paris Cedex 10, France.

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October 2012

A transcriptome signature of endothelial lymphatic cells coexists with the chronic oxidative stress signature in radiation-induced post-radiotherapy breast angiosarcomas.

Authors:
Nabila-Sandra Hadj-Hamou Marick Laé Anna Almeida Pierre de la Grange Youlia Kirova Xavier Sastre-Garau Bernard Malfoy

Carcinogenesis 2012 Jul 24;33(7):1399-405. Epub 2012 Apr 24.

Institut Curie, Centre de Recherche, UMR3244, 26 Rue d'Ulm Paris Cedex 5 F-75248, France.

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July 2012

Sperm transcriptome profiling in oligozoospermia.

Authors:
Debbie Montjean Pierre De La Grange David Gentien Audrey Rapinat Stéphanie Belloc Paul Cohen-Bacrie Yves Menezo Moncef Benkhalifa

J Assist Reprod Genet 2012 Jan 12;29(1):3-10. Epub 2011 Oct 12.

Advanced Technology Laboratory, ZA de l'Agiot 4 rue Louis Lormand, 78320, La Verrière, Paris, France.

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http://dx.doi.org/10.1007/s10815-011-9644-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252406PMC
January 2012

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

Authors:
Charlotte Fugier Arnaud F Klein Caroline Hammer Stéphane Vassilopoulos Ylva Ivarsson Anne Toussaint Valérie Tosch Alban Vignaud Arnaud Ferry Nadia Messaddeq Yosuke Kokunai Rie Tsuburaya Pierre de la Grange Doulaye Dembele Virginie Francois Guillaume Precigout Charlotte Boulade-Ladame Marie-Christine Hummel Adolfo Lopez de Munain Nicolas Sergeant Annie Laquerrière Christelle Thibault François Deryckere Didier Auboeuf Luis Garcia Pascale Zimmermann Bjarne Udd Benedikt Schoser Masanori P Takahashi Ichizo Nishino Guillaume Bassez Jocelyn Laporte Denis Furling Nicolas Charlet-Berguerand

Nat Med 2011 Jun 29;17(6):720-5. Epub 2011 May 29.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Institut National de la Santé et de la Recherche Médicale U964, Centre National de la Recherche Scientifique UMR7104, University of Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1038/nm.2374DOI Listing
June 2011

Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.

Authors:
Kiran Ramgolam Jessica Lauriol Claude Lalou Laura Lauden Laurence Michel Pierre de la Grange Abdel-Majid Khatib Fawzi Aoudjit Dominique Charron Catherine Alcaide-Loridan Reem Al-Daccak

PLoS One 2011 Apr 15;6(4):e18784. Epub 2011 Apr 15.

Unité Mixte de Recherche Scientifique 940, Institut National de la Santé et de la Recherche Médicale, Université Paris-Diderot Paris 7, Hôpital St Louis, Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078142PMC
April 2011

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB.

Authors:
Miriam Llorian Schraga Schwartz Tyson A Clark Dror Hollander Lit-Yeen Tan Rachel Spellman Adele Gordon Anthony C Schweitzer Pierre de la Grange Gil Ast Christopher W J Smith

Nat Struct Mol Biol 2010 Sep 15;17(9):1114-23. Epub 2010 Aug 15.

Department of Biochemistry, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/nsmb.1881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933513PMC
September 2010

Splicing factor and exon profiling across human tissues.

Authors:
Pierre de la Grange Lise Gratadou Marc Delord Martin Dutertre Didier Auboeuf

Nucleic Acids Res 2010 May 27;38(9):2825-38. Epub 2010 Jan 27.

GenoSplice technology, Centre Hayem, Hôpital Saint-Louis, 1 avenue Claude Vellefaux, 75010, Paris, France.

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http://dx.doi.org/10.1093/nar/gkq008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875023PMC
May 2010

The YTH domain is a novel RNA binding domain.

Authors:
Zhaiyi Zhang Dominik Theler Katarzyna H Kaminska Michael Hiller Pierre de la Grange Rainer Pudimat Ilona Rafalska Bettina Heinrich Janusz M Bujnicki Frédéric H-T Allain Stefan Stamm

J Biol Chem 2010 May 18;285(19):14701-10. Epub 2010 Feb 18.

Institute for Biochemistry, Universität Erlangen-Nuremberg, Fahrstrasse 17, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1074/jbc.M110.104711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863249PMC
May 2010

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

Authors:
Martin Dutertre Lise Gratadou Etienne Dardenne Sophie Germann Samaan Samaan Rosette Lidereau Keltouma Driouch Pierre de la Grange Didier Auboeuf

Cancer Res 2010 May 20;70(9):3760-70. Epub 2010 Apr 20.

Institut National de la Sante et de la Recherche Medicale, U590, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3988DOI Listing
May 2010

Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis.

Authors:
Martin Dutertre Magali Lacroix-Triki Keltouma Driouch Pierre de la Grange Lise Gratadou Samantha Beck Stefania Millevoi Jamal Tazi Rosette Lidereau Stephan Vagner Didier Auboeuf

Cancer Res 2010 Feb 26;70(3):896-905. Epub 2010 Jan 26.

INSERM UMRS 940, Paris, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2703DOI Listing
February 2010

Nonsense-mediated mRNA decay impacts MSI-driven carcinogenesis and anti-tumor immunity in colorectal cancers.

Authors:
Jamila El-Bchiri Agathe Guilloux Peggy Dartigues Etienne Loire Dominique Mercier Olivier Buhard Iradj Sobhani Pierre de la Grange Didier Auboeuf Françoise Praz Jean-François Fléjou Alex Duval

PLoS One 2008 Jul 9;3(7):e2583. Epub 2008 Jul 9.

INSERM, UMR S893, Team 13 Microsatellite Instability and Cancers, Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440797PMC
July 2008

Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.

Authors:
Jérôme Barbier Martin Dutertre Danielle Bittencourt Gabriel Sanchez Lise Gratadou Pierre de la Grange Didier Auboeuf

Mol Cell Biol 2007 Oct 20;27(20):7315-33. Epub 2007 Aug 20.

INSERM U685, Equipe AVENIR, Hopital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France.

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http://dx.doi.org/10.1128/MCB.00272-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168895PMC
October 2007

A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants.

Authors:
Pierre de la Grange Martin Dutertre Margot Correa Didier Auboeuf

BMC Bioinformatics 2007 Jun 4;8:180. Epub 2007 Jun 4.

INSERM U685/AVENIR, Centre G. Hayem, Hôpital Saint-Louis, Paris, France.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-8-180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904244PMC
June 2007

ASEtrap: a biological method for speeding up the exploration of spliceomes.

Authors:
Gilbert Thill Vanina Castelli Sophie Pallud Marcel Salanoubat Patrick Wincker Pierre de la Grange Didier Auboeuf Vincent Schächter Jean Weissenbach

Genome Res 2006 Jun 8;16(6):776-86. Epub 2006 May 8.

Genoscope-Centre National de Séquençage and Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR)-8030, 91000 Evry, France.

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http://dx.doi.org/10.1101/gr.5063306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479860PMC
June 2006

FAST DB: a website resource for the study of the expression regulation of human gene products.

Authors:
Pierre de la Grange Martin Dutertre Natalia Martin Didier Auboeuf

Nucleic Acids Res 2005 28;33(13):4276-84. Epub 2005 Jul 28.

INSERM U685/AVENIR, Centre G. Hayem, Institut Universitaire d'Hématologiem, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010 Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181862PMC
August 2005