Publications by authors named "Pierre Leblanc"

45Publications

Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease.

N Engl J Med 2020 05;382(20):1926-1932

From the Departments of Neurosurgery (J.S.S., B.S.C.), Neurology (T.M.H.), and Radiology (K.K., Q.L.), the Gordon Center for Medical Imaging (K.K., Q.L.), and the Division of Neuroradiology (O.R.), Massachusetts General Hospital, the Department of Pediatrics, Computational Health Informatics Program, Boston Children's Hospital (I.-H.L., S.-W.K.), and the Connell and O'Reilly Families Cell Manipulation Core Facility, Dana-Farber/Harvard Cancer Center (J.R.), Boston, and the Department of Psychiatry (B.M.C.) and the Molecular Neurobiology Laboratory (B.S., T.-Y.P., N.L., S.K., J.J., Y.C., H.S., J.K., T.K., P.L., K.-S.K.), McLean Hospital, Belmont - all in Massachusetts; the Departments of Neurology (C.H.) and Neurosurgery (M.K.) and the Brain and Mind Research Institute (G.A.P.), Weill Cornell Medical College, New York; the Department of Neurology, Kaiser Permanente, Irvine, CA (C.N.); and the Department of Molecular and Life Sciences, Hanyang University, Seoul, South Korea (H.S.).

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May 2020

Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases.

Sci Rep 2019 10 29;9(1):15559. Epub 2019 Oct 29.

Molecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, Massachusetts, 02478, USA.

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October 2019

Columnar Injection for Intracerebral Cell Therapy.

Oper Neurosurg (Hagerstown) 2020 03;18(3):321-328

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts.

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March 2020

Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.

Prog Neurobiol 2018 09 11;168:1-20. Epub 2018 Apr 11.

Department of Psychiatry, McLean Hospital, Harvard Medical School, United States; Molecular Neurobiology Laboratory, Program in Neuroscience and Harvard Stem Cell Institute, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA, 02478, United States. Electronic address:

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September 2018

AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression.

Cancer Immunol Res 2018 05 6;6(5):539-551. Epub 2018 Mar 6.

Vaccine and Immunotherapy Center, Infectious Diseases Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts.

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May 2018

Semiconductor diode laser device adjuvanting intradermal vaccine.

Vaccine 2017 04 30;35(18):2404-2412. Epub 2017 Mar 30.

Vaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, United States. Electronic address:

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April 2017

The authors reply.

Crit Care Med 2017 04;45(4):e459-e460

Assistance Publique des Hopitaux de Paris, Service d'Anesthésie-Réanimation de l'höpital Bichat, Paris, France;Centre Hospitalier Annecy Genevois, Annecy, France;Assistance Publique des Hopitaux de Paris, Service d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France;Assistance Publique des Hopitaux de Paris, Service d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France, Laboratoire d'Etude de la Microcirculation, "Bio-CANVAS: Biomarqueurs in CardiaNeuroVascular Diseases" UMRS 942, Paris, France;Assistance Publique des Hopitaux de Paris, Service d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France;Laboratoire d'Etude de la Microcirculation, "Bio-CANVAS: Biomarqueurs in CardiaNeuroVascular Diseases" UMRS 942, Paris, France;Assistance Publique des Hopitaux de Paris, Service d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France, Laboratoire d'Etude de la Microcirculation, "Bio-CANVAS: Biomarqueurs in CardiaNeuroVascular Diseases" UMRS 942, Paris, France.

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April 2017

Effect of RBC Transfusion on Sublingual Microcirculation in Hemorrhagic Shock Patients: A Pilot Study.

Crit Care Med 2017 Feb;45(2):e154-e160

1AP-HP, Departement d'Anesthésie-Réanimation, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France. 2Laboratoire d'Etude de la Microcirculation, "Bio-CANVAS: Biomarqueurs in CardiaNeuroVascular Diseases" UMRS 942, Paris, France.

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February 2017

4-amino-7-chloroquinoline derivatives for treating Parkinson's disease: implications for drug discovery.

Expert Opin Drug Discov 2016 7;11(4):337-41. Epub 2016 Mar 7.

a Molecular Neurobiology Laboratory , McLean Hospital and Program in Neuroscience, Harvard Medical School , Belmont , MA , USA.

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December 2016

Could mycobacterial Hsp70-containing fusion protein lead the way to an affordable therapeutic cancer vaccine?

Expert Rev Vaccines 2015 Mar 13;14(3):435-46. Epub 2014 Dec 13.

Vaccine and Immunotherapy Center, Massachusetts General Hospital - Medicine/Infectious Diseases, 149 13th Street, Mailstop 149-5-5246, Charlestown, MA 02129, USA.

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March 2015

Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease.

J Neurochem 2015 Jan 16;132(2):254-62. Epub 2014 Sep 16.

Molecular Neurobiology Laboratory, McLean Hospital/Harvard Medical School, Belmont, Massachusetts, USA; Program in Neuroscience, Harvard Medical School, Belmont, Massachusetts, USA.

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January 2015

Sudden loss of consciousness during a flight.

Cerebrovasc Dis 2014 26;37(6):470-1. Epub 2014 Jul 26.

Service de Neuroradiologie, CHU Bicêtre, Le Kremlin-Bicêtre, France.

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June 2015

Near-infrared laser adjuvant for influenza vaccine.

PLoS One 2013 11;8(12):e82899. Epub 2013 Dec 11.

Vaccine and Immunotherapy Center, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America.

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March 2015

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.

Proc Natl Acad Sci U S A 2012 Oct 8;109(43):17561-6. Epub 2012 Oct 8.

Edwin L Steele Laboratory of Tumor Biology, Department of Radiation Oncology and Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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October 2012

Accelerated vaccine development against emerging infectious diseases.

Hum Vaccin Immunother 2012 Jul 1;8(7):1010-2. Epub 2012 Jul 1.

Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital, Charlestown, MA, USA.

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July 2012

An alternative ultrasonographic approach to assess basilar artery flow.

Neurosurgery 2011 Jun;68(2 Suppl Operative):276-81; discussion 281

Assistance Publique-Hôpitaux de Paris, Université Paris-Sud, Hôpital de Bicêtre, Département d' Anesthésie-Réanimation, Le Kremlin-Bicêtre, France.

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June 2011

Gene transfer in the nervous system and implications for transsynaptic neuronal tracing.

Expert Opin Biol Ther 2010 May;10(5):763-72

Department of Anatomy and Neurobiology, Kyung Hee University, Seoul, Republic of Korea.

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May 2010

HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection.

J Infect Dis 2009 Oct;200(7):1050-3

Partners AIDS Research Center and Infectious Diseases Medicine, Massachusetts General Hospital (East), Charlestown, MA 02129, USA.

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October 2009

Locus of symptom limitation and exercise response to bronchodilation in chronic obstructive pulmonary disease.

J Cardiopulm Rehabil Prev 2008 May-Jun;28(3):208-14

Centre de recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Québec, Canada.

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October 2008

Profiling of mRNA expression in quadriceps of patients with COPD and muscle wasting.

COPD 2008 Apr;5(2):75-84

Centre de Recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Quebec, Canada.

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April 2008

Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2007 Aug 3;176(3):261-9. Epub 2007 May 3.

Centre de Recherche de l'Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Laval, Québec, Canada.

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August 2007

Chronic obstructive pulmonary disease in women.

Can Respir J 2007 Mar;14(2):93-8

Centre de recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Québec, Canada.

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March 2007

Ultra-rapid management of oral anticoagulant therapy-related surgical intracranial hemorrhage.

Intensive Care Med 2007 Apr 27;33(4):721-5. Epub 2007 Jan 27.

Département d'Anesthésie-Réanimation, AP-HP, Centre hospitalo-universitaire de Bicêtre, 78, rue du Général Leclerc, 94275, Le Kremlin-Bicêtre Cedex, France.

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April 2007

Six-minute walking versus shuttle walking: responsiveness to bronchodilation in chronic obstructive pulmonary disease.

Thorax 2007 Apr 10;62(4):291-8. Epub 2006 Nov 10.

Centre de Pneumologie, Hôpital Laval, 2725 Chemin Ste-Foy, Ste-Foy, Québec, G1V 4G5, Canada.

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April 2007

Skeletal muscle endurance and muscle metabolism in patients with chronic heart failure.

Can J Cardiol 2006 Apr;22(5):387-92

Centre de recherche, Hôpital Laval, Institut universitaire de cardiologie et de pneumologie, Université Laval, Ste-Foy, Québec, Canada.

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April 2006

Assessment of muscle fatigue during exercise in chronic obstructive pulmonary disease.

Muscle Nerve 2006 Jul;34(1):62-71

Centre de Recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, 2725 Chemin Ste-Foy, Québec G1V 4G5, Canada.

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July 2006

Use of facemask and mouthpiece to assess constant-workrate exercise capacity in COPD.

Med Sci Sports Exerc 2006 Feb;38(2):223-30

Centre de recherche, Hôpital Laval, Institut de Cardiologie et de Pneumologie de Québec, Département de Médecine, Université Laval, Québec, Canada.

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February 2006

Walking versus cycling: sensitivity to bronchodilation in chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2005 Dec 15;172(12):1517-22. Epub 2005 Sep 15.

Centre de Recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Ste-Foy, PQ, Canada.

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December 2005

Post-exercise heart rate recovery and mortality in chronic obstructive pulmonary disease.

Respir Med 2005 Jul 20;99(7):877-86. Epub 2005 Jan 20.

Centre de recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Qué., Canada.

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July 2005

Contractile fatigue, muscle morphometry, and blood lactate in chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2005 May 25;171(10):1109-15. Epub 2005 Feb 25.

Centre de Recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Québec, Canada.

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May 2005

Catabolic/anabolic balance and muscle wasting in patients with COPD.

Chest 2003 Jul;124(1):83-9

Centre de Recherche, Hôpital Laval, Institut Universitaire de Cardiologie et de Pneumologie, Université Laval, Sainte-Foy, QC, Canada.

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July 2003

Contractile leg fatigue after cycle exercise: a factor limiting exercise in patients with chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2003 Aug 24;168(4):425-30. Epub 2003 Apr 24.

Centre de Pneumologie, Hôpital Laval, 2725 Chemin Ste-Foy, Ste-Foy, PQ, G1V 4G5 Canada.

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August 2003

Exercise-induced quadriceps oxidative stress and peripheral muscle dysfunction in patients with chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2003 Jun 2;167(12):1664-9. Epub 2003 Apr 2.

UPRES-EA 701, Laboratory of Physiologie des Interactions, Service Central de Physiologie Clinique, Hôpital Arnaud de Villeneuve, 34295 Montpellier cedex 5, France.

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June 2003

Midthigh muscle cross-sectional area is a better predictor of mortality than body mass index in patients with chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2002 Sep;166(6):809-13

Centre de recherche, Hôpital Laval, Institut Universtaire de Cardiologie et de Pneumologie de L'Université Laval, Québec, Canada.

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September 2002

Lipofuscin accumulation in the vastus lateralis muscle in patients with chronic obstructive pulmonary disease.

Muscle Nerve 2002 Mar;25(3):383-9

Centre de Recherche, Institut de Cardiologie et de Pneumologie de l'Université Laval, Hôpital Laval, 2725 Chemin Ste-Foy, Ste-Foy, Québec, G1V 4G5 Canada.

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March 2002