Pierre Layrolle

Inserm, UMR 1238, PHY-OS, Bone sarcomas and remodeling of calcified tissues, Faculty of Medicine, University of Nantes, 1 rue Gaston Veil, Nantes 44035, France. Electronic address:

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September 2020

Regeneration of segmental defects in metatarsus of sheep with vascularized and customized 3D-printed calcium phosphate scaffolds.

Authors:

Luciano Vidal Carina Kampleitner Stéphanie Krissian Meadhbh Á Brennan Oskar Hoffmann Yago Raymond Yassine Maazouz Maria-Pau Ginebra Philippe Rosset Pierre Layrolle

Sci Rep 2020 04 27;10(1):7068. Epub 2020 Apr 27.

Inserm, UMR 1238, PHY-OS, Bone sarcomas and remodelling of calcified tissues, Faculty of Medicine, University of Nantes, Nantes, 44035, France.

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April 2020

A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect.

Authors:

Fiona E Freeman Meadhbh Á Brennan David C Browe Audrey Renaud Julien De Lima Daniel J Kelly Laoise M McNamara Pierre Layrolle

Front Bioeng Biotechnol 2020 31;8:230. Epub 2020 Mar 31.

INSERM, UMR 1238, PHY-OS, Laboratory of Bone Sarcomas and Remodelling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.

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March 2020

Early efficacy evaluation of mesenchymal stromal cells (MSC) combined to biomaterials to treat long bone non-unions.

Injury 2020 Apr 26;51 Suppl 1:S63-S73. Epub 2020 Feb 26.

INSERM U957, Lab. Pathophysiology of bone resorption, Faculty of Medicine, University of Nantes, Nantes, France.

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April 2020

Reconstruction of Large Skeletal Defects: Current Clinical Therapeutic Strategies and Future Directions Using 3D Printing.

Authors:

Luciano Vidal Carina Kampleitner Meadhbh Á Brennan Alain Hoornaert Pierre Layrolle

Front Bioeng Biotechnol 2020 12;8:61. Epub 2020 Feb 12.

INSERM, UMR 1238, PHY-OS, Bone Sarcomas and Remodeling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.

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February 2020

Biocompatibility and osseointegration of nanostructured titanium dental implants in minipigs.

Authors:

Alain Hoornaert Luciano Vidal Romain Besnier Jean-Francois Morlock Guy Louarn Pierre Layrolle

Clin Oral Implants Res 2020 Jun 28;31(6):526-535. Epub 2020 Feb 28.

Inserm, UMR 1238, PHY-OS, Bone Sarcomas and Remodeling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.

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June 2020

Cold Plasma-Treated Ringer's Saline: A Weapon to Target Osteosarcoma.

Authors:

Miguel Mateu-Sanz Juan Tornín Bénédicte Brulin Anna Khlyustova Maria-Pau Ginebra Pierre Layrolle Cristina Canal

Cancers (Basel) 2020 Jan 17;12(1). Epub 2020 Jan 17.

Biomaterials, Biomechanics and Tissue Engineering Group, Department Materials Science and Metallurgy, Technical University of Catalonia (UPC), Escola d'Enginyeria Barcelona Est (EEBE), c/Eduard Maristany 14, 08019 Barcelona, Spain.

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January 2020

Epinephrine Infiltration of Adipose Tissue Impacts MCF7 Breast Cancer Cells and Total Lipid Content.

Authors:

Pierre Avril Luciano Vidal Sophie Barille-Nion Louis-Romée Le Nail Françoise Redini Pierre Layrolle Michelle Pinault Stéphane Chevalier Pierre Perrot Valérie Trichet

Int J Mol Sci 2019 Nov 11;20(22). Epub 2019 Nov 11.

INSERM, Université de Nantes, UMR1238, Phy-Os, Sarcomes osseux et remodelage des tissus calcifiés, F-44035 Nantes, France.

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November 2019

Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells.

Authors:

Salwa Suliman Hassan R W Ali Tommy A Karlsen Jerome Amiaud Samih Mohamed-Ahmed Pierre Layrolle Daniela E Costea Jan E Brinchmann Kamal Mustafa

Sci Rep 2019 11 5;9(1):16031. Epub 2019 Nov 5.

Department of Clinical Dentistry, Centre for Clinical Dental Research, University of Bergen, Bergen, Norway.

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November 2019

Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner.

Authors:

Christelle Darrieutort-Laffite Paul Arnolfo Thomas Garraud Annie Adrait Yohann Couté Guy Louarn Valérie Trichet Pierre Layrolle Benoit Le Goff Frédéric Blanchard

J Clin Med 2019 Sep 26;8(10). Epub 2019 Sep 26.

INSERM UMR1238, Bone Sarcoma and remodeling of calcified tissues, Nantes University, 44093 Nantes, France.

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September 2019

Biomarkers of bone healing induced by a regenerative approach based on expanded bone marrow-derived mesenchymal stromal cells.

Authors:

Donatella Granchi Gabriela Ciapetti Enrique Gómez-Barrena Markus Rojewski Philippe Rosset Pierre Layrolle Benedetta Spazzoli Davide Maria Donati Nicola Baldini

Cytotherapy 2019 08 1;21(8):870-885. Epub 2019 Jul 1.

SSD Fisiopatologia Ortopedica e Medicina Rigenerativa, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; Dipartimento di Scienze Biomediche e Neuromotorie, Università degli Studi di Bologna, Bologna, Italy.

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August 2019

Biomaterials and regenerative technologies used in bone regeneration in the craniomaxillofacial region: Consensus report of group 2 of the 15th European Workshop on Periodontology on Bone Regeneration.

Authors:

Mariano Sanz Christer Dahlin Danae Apatzidou Zvi Artzi Darko Bozic Elena Calciolari Hugo De Bruyn Henrik Dommisch Nikos Donos Peter Eickholz Jan E Ellingsen Håvard J Haugen David Herrera France Lambert Pierre Layrolle Eduardo Montero Kamal Mustafa Omar Omar Henning Schliephake

J Clin Periodontol 2019 06;46 Suppl 21:82-91

Department of Oral and Maxillofacial Surgery, George-Augusta-University, Gottingen, Germany.

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June 2019

Immune Modulation by Transplanted Calcium Phosphate Biomaterials and Human Mesenchymal Stromal Cells in Bone Regeneration.

Authors:

Paul Humbert Meadhbh Á Brennan Noel Davison Philippe Rosset Valérie Trichet Frédéric Blanchard Pierre Layrolle

Front Immunol 2019 2;10:663. Epub 2019 Apr 2.

Laboratory Phy-Os, Inserm UMR1238, University of Nantes, Nantes, France.

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July 2020

Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.

Authors:

Xavier Leveque Mazene Hochane Fanny Geraldo Solene Dumont Catherine Gratas Lisa Oliver Claire Gaignier Valérie Trichet Pierre Layrolle Dominique Heymann Olivier Herault François M Vallette Christophe Olivier

Stem Cells 2019 08 17;37(8):1083-1094. Epub 2019 Apr 17.

CRCINA, INSERM U1232, Université de Nantes, Nantes, France.

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August 2019

Translation of a standardized manufacturing protocol for mesenchymal stromal cells: A systematic comparison of validation and manufacturing data.

Authors:

Markus Thomas Rojewski Ramin Lotfi Cecilie Gjerde Kamal Mustafa Elena Veronesi Aymen B Ahmed Markus Wiesneth Sixten Körper Luc Sensebé Pierre Layrolle Sølve Hellem Hubert Schrezenmeier

Cytotherapy 2019 04 27;21(4):468-482. Epub 2019 Mar 27.

Institute for Transfusion Medicine, University Hospital Ulm, Ulm, Germany; Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Donation Service Baden-Württemberg - Hessia, Ulm, Germany.

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April 2019

Vertical Bone Regeneration with Synthetic Biomimetic Calcium Phosphate onto the Calvaria of Rats.

Authors:

Alain Hoornaert Yassine Maazouz David Pastorino Carlos Aparicio Gonzague de Pinieux Borhane H Fellah Maria-Pau Ginebra Pierre Layrolle

Tissue Eng Part C Methods 2019 01;25(1):1-11

1 Inserm, UMR 1238, PHY-OS, Laboratory of Bone Sarcomas and Remodelling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.

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January 2019

Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial.

Authors:

Cecilie Gjerde Kamal Mustafa Sølve Hellem Markus Rojewski Harald Gjengedal Mohammed Ahmed Yassin Xin Feng Siren Skaale Trond Berge Annika Rosen Xie-Qi Shi Aymen B Ahmed Bjørn Tore Gjertsen Hubert Schrezenmeier Pierre Layrolle

Stem Cell Res Ther 2018 08 9;9(1):213. Epub 2018 Aug 9.

INSERM, UMR 1238, PHY-OS, Laboratory of Bone Sarcomas and Remodeling of Calcified Tissues, Faculty of Medicine, University of Nantes, Nantes, France.

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August 2018

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