Pierre Blier

Pierre Blier

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Pierre Blier

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Linking paternally inherited mtDNA variants and sperm performance.

Philos Trans R Soc Lond B Biol Sci 2020 Jan 2;375(1790):20190177. Epub 2019 Dec 2.

Département des Sciences Biologiques, Université de Montréal, Montréal, Québec, Canada H2V 2S9.

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http://dx.doi.org/10.1098/rstb.2019.0177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939365PMC
January 2020

The CINP guidelines on the definition and the evidence-based interventions for treatment-resistant Bipolar disorder.

Int J Neuropsychopharmacol 2019 Dec 5. Epub 2019 Dec 5.

Professor Psychiatric Department Ludwig Maximilians University Munich, Germany.

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http://dx.doi.org/10.1093/ijnp/pyz064DOI Listing
December 2019

Ketamine for chronic depression: two cautionary tales

J Psychiatry Neurosci 2019 Nov;44(6):384-385

From the The Royal’s Institute of Mental Health Research, Mood Disorders Research Unit, Ottawa, Ont. (Talbot, Phillips, Blier); and the Department of Psychiatry, University of Ottawa, Ottawa, Ont. (Talbot, Phillips, Blier).

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http://dx.doi.org/10.1503/jpn.190073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821514PMC
November 2019

Cardiac mitochondrial plasticity and thermal sensitivity in a fish inhabiting an artificially heated ecosystem.

Sci Rep 2019 Nov 28;9(1):17832. Epub 2019 Nov 28.

Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, 405 30, Sweden.

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http://dx.doi.org/10.1038/s41598-019-54165-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883045PMC
November 2019

Cardiac mitochondrial plasticity and thermal sensitivity in a fish inhabiting an artificially heated ecosystem.

Sci Rep 2019 Nov 28;9(1):17832. Epub 2019 Nov 28.

Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, 405 30, Sweden.

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http://dx.doi.org/10.1038/s41598-019-54165-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883045PMC
November 2019

Single, Repeated, and Maintenance Ketamine Infusions for Treatment-Resistant Depression: A Randomized Controlled Trial.

Am J Psychiatry 2019 05 29;176(5):401-409. Epub 2019 Mar 29.

From the Mood Disorders Research Unit, The Royal's Institute of Mental Health Research, Ottawa (Phillips, Norris, Talbot, Birmingham, Hatchard, Ortiz, Owoeye, Batten, Blier); the Department of Psychiatry, University of Ottawa (Phillips, Norris, Talbot, Owoeye, Blier); and the Department of Cellular and Molecular Medicine, University of Ottawa (Blier).

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http://dx.doi.org/10.1176/appi.ajp.2018.18070834DOI Listing
May 2019

Synergistic effect of aripiprazole and escitalopram in increasing serotonin but not norepinephrine neurotransmission in the rat hippocampus.

Neuropharmacology 2019 03 8;146:12-18. Epub 2018 Nov 8.

University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, ON, K1Z 7K4, Canada.

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http://dx.doi.org/10.1016/j.neuropharm.2018.11.006DOI Listing
March 2019

Switching medication products during the treatment of psychiatric illness.

Int J Psychiatry Clin Pract 2019 Mar 8;23(1):2-13. Epub 2019 Feb 8.

d Department of Pharmacology & Therapeutics , McGill University, McIntyre Medical Science Building , Montréal , QC , Canada.

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http://dx.doi.org/10.1080/13651501.2018.1508724DOI Listing
March 2019

Life-history trade-offs and limitations associated with phenotypic adaptation under future ocean warming and elevated salinity.

Philos Trans R Soc Lond B Biol Sci 2019 03;374(1768):20180428

1 Département de Biologie Chimie et Géographie, Université du Québec à Rimouski , 300 Allée des Ursulines, Rimouski, Quebec, Canada G5L 3A1.

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http://dx.doi.org/10.1098/rstb.2018.0428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365865PMC
March 2019

Age Dependent Dysfunction of Mitochondrial and ROS Metabolism Induced by Mitonuclear Mismatch.

Front Genet 2019 20;10:130. Epub 2019 Feb 20.

Laboratoire de Physiologie Animale Intégrative, Département de Biologie, Université du Québec à Rimouski, Rimouski, QC, Canada.

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http://dx.doi.org/10.3389/fgene.2019.00130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391849PMC
February 2019

Metabolic remodelling associated with mtDNA: insights into the adaptive value of doubly uniparental inheritance of mitochondria.

Proc Biol Sci 2019 02;286(1896):20182708

1 Département de Sciences Biologiques, Université de Montréal , Montréal, QC, Canada H2V 2S9.

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http://dx.doi.org/10.1098/rspb.2018.2708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408612PMC
February 2019

Energy metabolism and survival of the juvenile recruits of the American lobster (Homarus americanus) exposed to a gradient of elevated seawater pCO.

Mar Environ Res 2019 Jan 9;143:111-123. Epub 2018 Oct 9.

Département de Biologie, Chimie et Géographie, Université du Québec à Rimouski, 300 Allée des Ursulines, Rimouski, Québec, G5L 3A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.marenvres.2018.10.002DOI Listing
January 2019

Effects of fasting and refeeding on protein and glucose metabolism in Arctic charr.

Comp Biochem Physiol A Mol Integr Physiol 2018 12 23;226:66-74. Epub 2018 Aug 23.

Département de biologie, Université de Moncton, Moncton, NB E1A 3E9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2018.08.010DOI Listing
December 2018

Involvement of 5-HT and 5-HT Receptors but Not -Adrenoceptors in the Acute Electrophysiological Effects of Cariprazine in the Rat Brain In Vivo.

Mol Pharmacol 2018 12 15;94(6):1363-1370. Epub 2018 Oct 15.

Mood Disorders Research Unit, University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada (A.H., M.E.M., P.B.); Allergan, Madison, New Jersey, United States (N.A.); and Gedeon Richter Plc, Budapest, Hungary (B.K., B.F.).

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http://dx.doi.org/10.1124/mol.118.113290DOI Listing
December 2018

Optimized regimens of combined medications for the treatment of major depressive disorder: a double-blind, randomized-controlled trial.

Neuropsychiatr Dis Treat 2018 22;14:3209-3218. Epub 2018 Nov 22.

Department of Psychiatry, University of Ottawa, The Royal Ottawa Institute of Mental Health Research, Ottawa, ON, Canada,

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http://dx.doi.org/10.2147/NDT.S175203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257360PMC
November 2018

Hybridization between char species ( and ): a fast track for novel allometric trajectories.

Biol Open 2018 Oct 19;7(10). Epub 2018 Oct 19.

Département de biologie, chimie et géographie, Université du Québec à Rimouski, 300, Allée des Ursulines, Rimouski, QC, Canada G5L 3A1

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http://bio.biologists.org/lookup/doi/10.1242/bio.033332
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http://dx.doi.org/10.1242/bio.033332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215407PMC
October 2018

Large muscles are beneficial but not required for improving thermogenic capacity in small birds.

Sci Rep 2018 09 18;8(1):14009. Epub 2018 Sep 18.

Département de biologie, chimie et géographie, Université du Québec à Rimouski, Rimouski, Québec, Canada.

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http://dx.doi.org/10.1038/s41598-018-32041-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143541PMC
September 2018

Mitochondrial phenotype during torpor: Modulation of mitochondrial electron transport system in the Chilean mouse-opossum Thylamys elegans.

Comp Biochem Physiol A Mol Integr Physiol 2018 07 15;221:7-14. Epub 2018 Mar 15.

Département de Biologie, Laboratoire de Physiologie Animale Intégrative, Université du Québec, Rimouski G5L 3A1, QC, Canada.

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http://dx.doi.org/10.1016/j.cbpa.2017.12.014DOI Listing
July 2018

Pre-treatment EEG signal variability is associated with treatment success in depression.

Neuroimage Clin 2018 31;17:368-377. Epub 2017 Oct 31.

Department of Psychology, University of Calgary, AB, Canada.

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http://dx.doi.org/10.1016/j.nicl.2017.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683802PMC
June 2018

Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production.

Free Radic Biol Med 2018 02 30;116:11-18. Epub 2017 Dec 30.

Université du Québec à Rimouski, Département de biologie, Rimouski, Québec, Canada G5L3A1. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.12.037DOI Listing
February 2018

Partial inhibition of catecholamine activity and enhanced responsiveness to NMDA after sustained administration of vortioxetine.

Neuropharmacology 2018 Jan 13;128:425-432. Epub 2017 Nov 13.

University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, ON, K1Z 7K4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.10.036DOI Listing
January 2018

What modulates animal longevity? Fast and slow aging in bivalves as a model for the study of lifespan.

Semin Cell Dev Biol 2017 10 1;70:130-140. Epub 2017 Aug 1.

Linus Pauling Institute, Oregon State University, 335 Linus Pauling Science Center, Corvallis, OR 97331, USA.

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http://dx.doi.org/10.1016/j.semcdb.2017.07.046DOI Listing
October 2017

Progress on the Neuroscience-Based Nomenclature (NbN) for Psychotropic Medications.

Neuropsychopharmacology 2017 09 9;42(10):1927-1928. Epub 2017 Feb 9.

University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/npp.2017.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561343PMC
September 2017

Eicosapentaenoic acid monoglyceride resolves inflammation in an ex vivo model of human peripheral blood mononuclear cell.

Eur J Pharmacol 2017 Jul 10;807:205-211. Epub 2017 May 10.

SCF Pharma, Ste-Luce, QC, Canada; Départment de Biologie, Université du Québec à Rimouski, Rimouski, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2017.05.018DOI Listing
July 2017

Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers.

Sci Rep 2017 06 6;7(1):2840. Epub 2017 Jun 6.

D. Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University Innsbruck, 6020, Innsbruck, Austria.

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http://dx.doi.org/10.1038/s41598-017-02789-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460290PMC
June 2017

Evolved genetic and phenotypic differences due to mitochondrial-nuclear interactions.

PLoS Genet 2017 03 31;13(3):e1006517. Epub 2017 Mar 31.

Marine Biology and Ecology, Rosenstiel School of Marine and Atmospheric Sciences, University of Miami, Rickenbacker Causeway, Miami, FL, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375140PMC
March 2017

The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 4: Unmet Needs in the Treatment of Bipolar Disorder and Recommendations for Future Research.

Int J Neuropsychopharmacol 2017 02;20(2):196-205

3rd Department of Psychiatry, School of Medicine Aristotle University of Thessaloniki Greece; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain; Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, United Kingdom; Department of Psychiatry, University of British Columbia, Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, Canada; Paracelsus Medical University, Salzburg, Austria; The Royal Institute of Mental Health Research, Department of Psychiatry, University of Ottawa, Ottawa, Canada; Psychiatric Department Ludwig Maximilians University, Munich, Germany; Department of Psychiatry and Psychotherapy, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1093/ijnp/pyw072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408978PMC
February 2017

The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines.

Int J Neuropsychopharmacol 2017 02;20(2):98-120

3rd Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece; Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK; Department of Psychiatry, University of British Columbia, Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, Canada; Paracelsus Medical University, Salzburg, Austria; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain; The Royal Institute of Mental Health Research, Department of Psychiatry, University of Ottawa, Ottawa, Canada; Psychiatric Department, Ludwig Maximilians University, Munich, Germany; Department of Psychiatry and Psychotherapy, Medical University Vienna, MUV, AKH, Vienna, Austria.

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http://dx.doi.org/10.1093/ijnp/pyw091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408969PMC
February 2017

The International College of Neuro-Psychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 2: Review, Grading of the Evidence, and a Precise Algorithm.

Int J Neuropsychopharmacol 2017 02;20(2):121-179

3rd Department of Psychiatry, School of Medicine, Aristotle University, Thessaloniki, Greece; Department of Psychiatry, University of British Columbia, Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Canada; Paracelsus Medical University, Salzburg, Austria; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain; Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, United Kingdom; The Royal Institute of Mental Health Research, Department of Psychiatry, University of Ottawa, Ottawa, Canada; Department of Psychiatry and Psychotherapy, Medical University Vienna, MUV, AKH, Vienna, Austria; Psychiatric Department Ludwig Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1093/ijnp/pyw100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409012PMC
February 2017

Thermal sensitivity and phenotypic plasticity of cardiac mitochondrial metabolism in European perch, Perca fluviatilis.

J Exp Biol 2017 02 16;220(Pt 3):386-396. Epub 2016 Nov 16.

Department of Biological and Environmental Sciences, University of Gothenburg, 41390 Gothenburg, Sweden.

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http://dx.doi.org/10.1242/jeb.150698DOI Listing
February 2017

Can multi-generational exposure to ocean warming and acidification lead to the adaptation of life history and physiology in a marine metazoan?

J Exp Biol 2017 02 30;220(Pt 4):551-563. Epub 2016 Nov 30.

Département de biologie, chimie et géographie, Université du Québec à Rimouski, 300 Allée des Ursulines, Rimouski, QC, Canada G5L 3A1.

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http://dx.doi.org/10.1242/jeb.149989DOI Listing
February 2017

The International College of Neuro-Psychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 3: The Clinical Guidelines.

Int J Neuropsychopharmacol 2017 02;20(2):180-195

3rd Department of Psychiatry, School of Medicine, Aristotle University, Thessaloniki, Greece; Paracelsus Medical University, Salzburg, Austria; Hospital Clinic, Institute of Neuroscience, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain; Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Department of Psychiatry, University of British Columbia, Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, Canada; The Royal Institute of Mental Health Research, Department of Psychiatry, University of Ottawa, Ottawa, Canada; Department of Psychiatry and Psychotherapy, Medical University Vienna, MUV, AKH, Vienna, Austria; Psychiatric Department, Ludwig Maximilians University, Munich, Germany.

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http://dx.doi.org/10.1093/ijnp/pyw109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408976PMC
February 2017

Inverse agonists - What do they mean for psychiatry?

Eur Neuropsychopharmacol 2017 01 7;27(1):87-90. Epub 2016 Dec 7.

Centre for Psychiatry, Imperial College London, UK.

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http://dx.doi.org/10.1016/j.euroneuro.2016.11.013DOI Listing
January 2017

A Neuroscience-Based Nomenclature (NbN) for Psychotropic Agents.

Int J Neuropsychopharmacol 2016 08 12;19(8). Epub 2016 Aug 12.

Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (Dr Frazer); Departments of Psychiatry and Cellular & Molecular Medicine, University of Ottawa, Ottawa, Canada (Dr Blier).

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http://dx.doi.org/10.1093/ijnp/pyw066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006202PMC
August 2016

Altered monoamine system activities after prenatal and adult stress: A role for stress resilience?

Brain Res 2016 07 14;1642:409-418. Epub 2016 Apr 14.

University of Ottawa, Institute of Mental Health Research, Ontario, Canada; Department of Cellular and Molecular medicine, University of Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.brainres.2016.04.032DOI Listing
July 2016

Gene by environmental interactions affecting oxidative phosphorylation and thermal sensitivity.

Am J Physiol Regul Integr Comp Physiol 2016 07 25;311(1):R157-65. Epub 2016 May 25.

Marine Biology and Ecology, Rosenstiel School of Marine and Atmospheric Sciences, University of Miami, Miami, Florida;

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http://dx.doi.org/10.1152/ajpregu.00008.2016DOI Listing
July 2016

An overview of vortioxetine.

J Clin Psychiatry 2014 Dec;75(12):1411-8

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http://dx.doi.org/10.4088/JCP.14027ah1DOI Listing
December 2014

MAG-EPA reduces severity of DSS-induced colitis in rats.

Am J Physiol Gastrointest Liver Physiol 2016 05 24;310(10):G808-21. Epub 2016 Mar 24.

SCF Pharma, Ste-Luce, Quebec, Canada; Department of Biology, Université du Québec à Rimouski, Rimouski, Quebec, Canada

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http://dx.doi.org/10.1152/ajpgi.00136.2015DOI Listing
May 2016

Neuroscience-based Nomenclature (NbN) for Journal of Psychopharmacology.

J Psychopharmacol 2016 05;30(5):413-5

Department of Psychiatry and Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1177/0269881116642903DOI Listing
May 2016

The noradrenergic paradox: implications in the management of depression and anxiety.

Neuropsychiatr Dis Treat 2016 1;12:541-57. Epub 2016 Mar 1.

Mood Disorders Research Unit, Institute of Mental Health Research, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.2147/NDT.S91311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780187PMC
April 2016

Neurobiology of depression and mechanism of action of depression treatments.

Authors:
Pierre Blier

J Clin Psychiatry 2016 Mar;77(3):e319

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http://dx.doi.org/10.4088/JCP.13097tx3cDOI Listing
March 2016

The separate and combined effects of monoamine oxidase A inhibition and nicotine on resting state EEG.

J Psychopharmacol 2016 Jan 4;30(1):56-62. Epub 2015 Nov 4.

University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.

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http://dx.doi.org/10.1177/0269881115613518DOI Listing
January 2016

Mitochondrial phenotype of marsupial torpor: Fuel metabolic switch in the Chilean mouse-opossum Thylamys elegans.

J Exp Zool A Ecol Genet Physiol 2016 Jan 10;325(1):41-51. Epub 2015 Nov 10.

Département de Biologie, Laboratoire de Physiologie Animale Intégrative, Université du Québec, Rimouski QC, Canada.

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http://dx.doi.org/10.1002/jez.1994DOI Listing
January 2016

Impact of monoamine-related gene polymorphisms on hippocampal volume in treatment-resistant depression.

Acta Neuropsychiatr 2015 Dec 20;27(6):353-61. Epub 2015 May 20.

1University of Ottawa Institute of Mental Health Research,Ottawa,Canada.

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http://dx.doi.org/10.1017/neu.2015.25DOI Listing
December 2015

Long-term administration of the antidepressant vilazodone modulates rat brain monoaminergic systems.

Neuropharmacology 2015 Dec 8;99:696-704. Epub 2015 Sep 8.

University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, ON, K1Z 7K4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.09.007DOI Listing
December 2015

A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature.

Eur Neuropsychopharmacol 2015 Dec 7;25(12):2318-25. Epub 2015 Sep 7.

Centre for Neuropsychopharmacology Division of Brain Sciences Imperial College, London, UK.

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http://dx.doi.org/10.1016/j.euroneuro.2015.08.019DOI Listing
December 2015

Data mining EEG signals in depression for their diagnostic value.

BMC Med Inform Decis Mak 2015 Dec 23;15:108. Epub 2015 Dec 23.

Institute of Mental Health Research at the Royal Ottawa Mental Health Care Centre, University of Ottawa, 1145 Carling Avenue, Ottawa, ON, K1Z 7 K4, Canada.

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http://dx.doi.org/10.1186/s12911-015-0227-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690290PMC
December 2015

The separate and combined effects of monoamine oxidase A inhibition and nicotine on the mismatch negativity event related potential.

Pharmacol Biochem Behav 2015 Oct 28;137:44-52. Epub 2015 Jul 28.

University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada; Royal Ottawa Mental Health Centre, Ottawa, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00913057153003
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http://dx.doi.org/10.1016/j.pbb.2015.07.008DOI Listing
October 2015

Brexpiprazole Alters Monoaminergic Systems following Repeated Administration: an in Vivo Electrophysiological Study.

Int J Neuropsychopharmacol 2015 Oct 1;19(3):pyv111. Epub 2015 Oct 1.

Institute of Mental Health Research (Dr Oosterhof, Dr El Mansari, and Dr Blier), and Department of Cellular and Molecular Medicine (Dr Oosterhof and Dr Blier), University of Ottawa, Ottawa, Ontario, Canada; Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (Dr Bundgaard).

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http://dx.doi.org/10.1093/ijnp/pyv111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815476PMC
October 2015

Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain.

Psychopharmacology (Berl) 2015 Jul 11;232(13):2343-52. Epub 2015 Feb 11.

University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, ON, K1Z 7K4, Canada.

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http://dx.doi.org/10.1007/s00213-015-3870-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464372PMC
July 2015

Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons.

J Psychopharmacol 2015 Jul 10;29(7):792-801. Epub 2015 Mar 10.

University of Ottawa Institute of Mental Health Research, Mood Disorders Research, Ottawa, ON, Canada.

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http://dx.doi.org/10.1177/0269881115573809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469544PMC
July 2015

Effect of docosahexaenoic acid monoacylglyceride on systemic hypertension and cardiovascular dysfunction.

Am J Physiol Heart Circ Physiol 2015 Jul 24;309(1):H93-H102. Epub 2015 Apr 24.

SCF Pharma, Sainte-Luce, Quebec, Canada; Department of Biology, Université du Québec à Rimouski, Rimouski, Quebec, Canada.

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http://ajpheart.physiology.org/content/ajpheart/309/1/H93.fu
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http://ajpheart.physiology.org/content/ajpheart/early/2015/0
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http://ajpheart.physiology.org/lookup/doi/10.1152/ajpheart.0
Publisher Site
http://dx.doi.org/10.1152/ajpheart.00823.2014DOI Listing
July 2015

The separate and combined effects of monoamine oxidase inhibition and nicotine on P50 sensory gating.

Psychopharmacology (Berl) 2015 Jun 4;232(11):1911-20. Epub 2014 Dec 4.

University of Ottawa Institute of Mental Health Research, 1145 Carling Ave., Ottawa, ON, Canada, K1Z 7K4,

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http://dx.doi.org/10.1007/s00213-014-3823-8DOI Listing
June 2015

Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry.

J Exp Zool A Ecol Genet Physiol 2015 Jun 10;323(5):292-300. Epub 2015 Apr 10.

Campus Saint-Jean, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1002/jez.1913DOI Listing
June 2015

Concomitant benzodiazepine use attenuates ketamine response: implications for large scale study design and clinical development.

J Clin Psychopharmacol 2015 Jun;35(3):334-6

Department of Psychiatry and Psychology Mayo Clinic Depression Center Mayo Clinic Rochester, MN University of Ottawa Institute of Mental Health Research Mood Disorders Research Ottawa, Ontario, Canada Department of Psychiatry and Psychology Mayo Clinic Depression Center Mayo Clinic Rochester, MN.

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http://dx.doi.org/10.1097/JCP.0000000000000316DOI Listing
June 2015

Treatment of maternal depression in a medication clinical trial and its effect on children.

Am J Psychiatry 2015 May 23;172(5):450-9. Epub 2015 Jan 23.

From the Department of Psychiatry, the Department of Child and Adolescent Psychiatry, and the Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York; New York State Psychiatric Institute, New York; the Institute of Mental Health Research, University of Ottawa, Ottawa; the Department of Psychology, Carleton University, Ottawa; and the Department of Child and Adolescent Psychiatry, Cornell University, Ithaca, N.Y.

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2014.13
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http://dx.doi.org/10.1176/appi.ajp.2014.13121679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417045PMC
May 2015

Age, diet, and season do not affect longevity-related differences in peroxidation index between Spisula solidissima and Arctica islandica.

J Gerontol A Biol Sci Med Sci 2015 Apr 29;70(4):434-43. Epub 2014 Apr 29.

Laboratoire de physiologie animale intégrative, Department of Biology, Université du Québec à Rimouski, Canada.

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http://dx.doi.org/10.1093/gerona/glu054DOI Listing
April 2015

Asenapine alters the activity of monoaminergic systems following its subacute and long-term administration: an in vivo electrophysiological characterization.

Eur Neuropsychopharmacol 2015 Apr 15;25(4):531-43. Epub 2015 Jan 15.

Institute of Mental Health Research, University of Ottawa, Ontario, Canada; Department of Cellular and Molecular medicine, University of Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.euroneuro.2015.01.006DOI Listing
April 2015

A Prospective, Longitudinal Study of the Effect of Remission on Cortical Thickness and Hippocampal Volume in Patients with Treatment-Resistant Depression.

Int J Neuropsychopharmacol 2015 Mar 30;18(8). Epub 2015 Mar 30.

University of Ottawa Institute of Mental Health Research, Ottawa, Canada (Drs Phillips, Batten, Tremblay, Aldosary, and Blier); Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada (Drs Phillips and Blier).

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http://dx.doi.org/10.1093/ijnp/pyv037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571636PMC
March 2015

Acute effects of brexpiprazole on serotonin, dopamine, and norepinephrine systems: an in vivo electrophysiologic characterization.

J Pharmacol Exp Ther 2014 Dec 15;351(3):585-95. Epub 2014 Sep 15.

Institute of Mental Health Research (C.A.O., M.E.M., P.B.) and Department of Cellular and Molecular Medicine (C.A.O., P.B.), University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1124/jpet.114.218578DOI Listing
December 2014

An overview of vortioxetine.

J Clin Psychiatry 2014 Dec;75(12):1411-8

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http://dx.doi.org/10.4088/JCP.14027ah1DOI Listing
December 2014

Does negative affectivity predict differential response to an SSRI versus a non-SSRI antidepressant?

J Clin Psychiatry 2014 Sep;75(9):e939-44

Department of Neuroscience, Psychiatry Unit, University General Hospital, Braga Bldg, Via Gramsci 14, Parma, PR 43126, Italy

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http://dx.doi.org/10.4088/JCP.14m09025DOI Listing
September 2014

Psychopathology and functioning among children of treated depressed fathers and mothers.

J Affect Disord 2014 Aug 18;164:107-11. Epub 2014 Apr 18.

Division of Epidemiology at the New York State Psychiatric Institute, USA; Department of Epidemiology at the Mailman School of Public Health at Columbia University, USA; Department of Psychiatry of the College of Physicians and Surgeons at Columbia University, USA.

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http://dx.doi.org/10.1016/j.jad.2014.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152938PMC
August 2014

Rational site-directed pharmacotherapy for major depressive disorder.

Authors:
Pierre Blier

Int J Neuropsychopharmacol 2014 Jul 10;17(7):997-1008. Epub 2013 Jun 10.

University of Ottawa Institute of Mental Health Research,Ottawa, Ontario,Canada.

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http://dx.doi.org/10.1017/S1461145713000400DOI Listing
July 2014

Role of melatonin, serotonin 2B, and serotonin 2C receptors in modulating the firing activity of rat dopamine neurons.

J Psychopharmacol 2014 Feb 4;28(2):162-7. Epub 2013 Nov 4.

Institute of Mental Health Research, University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1177/0269881113510071DOI Listing
February 2014

Auditory P3 in antidepressant pharmacotherapy treatment responders, non-responders and controls.

Eur Neuropsychopharmacol 2013 Nov 9;23(11):1561-9. Epub 2013 May 9.

University of Ottawa, Institute of Mental Health Research, Ottawa, Ont., Canada; Department of Psychology, University of Ottawa, Ottawa, Ont., Canada; Department of Psychiatry, Hotchkiss Brain Institute (HBI), Alberta Children's Hospital Research Institute (ACRI), University of Calgary, Calgary, Alta., Canada. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744638PMC
November 2013

Modulation of the antidepressant-like effects of sustained administration of carisbamate and lamotrigine on monoaminergic systems: electrophysiological studies in the rat brain.

J Pharmacol Exp Ther 2013 Nov 28;347(2):487-96. Epub 2013 Aug 28.

University of Ottawa Institute of Mental Health Research (S.S., M.E.M., P.B.) and Department of Cellular and Molecular Medicine, University of Ottawa (S.S., P.B.), Ottawa, Ontario, Canada.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.113.20331
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November 2013

Effects of repeated electroconvulsive shocks on catecholamine systems: electrophysiological studies in the rat brain.

Synapse 2013 Oct 4;67(10):716-27. Epub 2013 Jul 4.

Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, K1Z 7K4, Canada.

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http://dx.doi.org/10.1002/syn.21685DOI Listing
October 2013

Serotonin and beyond: therapeutics for major depression.

Philos Trans R Soc Lond B Biol Sci 2013 25;368(1615):20120536. Epub 2013 Feb 25.

Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1098/rstb.2012.0536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638389PMC
September 2013

Low hydrogen peroxide production in mitochondria of the long-lived Arctica islandica: underlying mechanisms for slow aging.

Aging Cell 2013 Aug 6;12(4):584-92. Epub 2013 May 6.

Biology Department, Université du Québec à Rimouski, 300, allée des Ursulines, CP 3300, succ. A, Rimouski, QC, Canada, G5L 3A1.

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http://dx.doi.org/10.1111/acel.12082DOI Listing
August 2013

Monoamine neurocircuitry in depression and strategies for new treatments.

Prog Neuropsychopharmacol Biol Psychiatry 2013 Aug 19;45:54-63. Epub 2013 Apr 19.

INSERM U894, Centre of Psychiatry and Neurosciences, Paris, France.

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http://dx.doi.org/10.1016/j.pnpbp.2013.04.009DOI Listing
August 2013

Exploiting N-methyl-d-aspartate channel blockade for a rapid antidepressant response in major depressive disorder.

Authors:
Pierre Blier

Biol Psychiatry 2013 Aug;74(4):238-9

University of Ottawa Institute of Mental Health Research, Mood Disorders Research, Ottawa, Canada.

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http://dx.doi.org/10.1016/j.biopsych.2013.05.029DOI Listing
August 2013

Ms Phillips and Dr Blier reply.

J Clin Psychiatry 2013 Jun;74(6):631-2

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http://dx.doi.org/10.4088/JCP.12lr08004aDOI Listing
June 2013

Serotonin and beyond: therapeutics for major depression.

Philos Trans R Soc Lond B Biol Sci 2013 25;368(1615):20120536. Epub 2013 Feb 25.

Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1098/rstb.2012.0536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638389PMC
September 2013

Residual symptoms in major depressive disorder: prevalence, effects, and management.

J Clin Psychiatry 2013 Apr;74(4):407-14

Depression Treatment Research Center, Rush University Medical Center, Chicago, Illinois, USA.

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http://dx.doi.org/10.4088/JCP.12059ah1DOI Listing
April 2013