Publications by authors named "Pierre Bedossa"

259Publications

Advanced Liver Fibrosis Is Common in Patients With Type 2 Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening.

Authors:
Romina Lomonaco Eddison Godinez Leiva Fernando Bril Sulav Shrestha Lydia Mansour Jeff Budd Jessica Portillo Romero Siegfried Schmidt Ku-Lang Chang George Samraj John Malaty Katherine Huber Pierre Bedossa Srilaxmi Kalavalapalli Jonathan Marte Diana Barb Danielle Poulton Nada Fanous Kenneth Cusi

Diabetes Care 2021 Feb 21;44(2):399-406. Epub 2020 Dec 21.

Division of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL

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February 2021

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis.

Authors:
Olivier Govaere Simon Cockell Dina Tiniakos Rachel Queen Ramy Younes Michele Vacca Leigh Alexander Federico Ravaioli Jeremy Palmer Salvatore Petta Jerome Boursier Chiara Rosso Katherine Johnson Kristy Wonders Christopher P Day Mattias Ekstedt Matej Orešič Rebecca Darlay Heather J Cordell Fabio Marra Antonio Vidal-Puig Pierre Bedossa Jörn M Schattenberg Karine Clément Michael Allison Elisabetta Bugianesi Vlad Ratziu Ann K Daly Quentin M Anstee

Sci Transl Med 2020 Dec;12(572)

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

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December 2020

Microcirculatory changes in the liver of patients with refractory ascites and their relationship with diabetes and alcohol.

Authors:
Laure Elkrief Sophie Buyse Xavière Panhard Clotilde Baudry Nathalie Gault Richard Moreau Pierre-Emmanuel Rautou Jacques Belghiti François Durand Pierre Bedossa Valérie Paradis Dominique Valla

Eur J Gastroenterol Hepatol 2020 Nov 17. Epub 2020 Nov 17.

DHU UNITY, Service d'Hépatologie, Hôpital Beaujon - AP-HP, Clichy France and Centre de recherché sur l'Inflammation (CRI), INSERM, Université Paris Diderot-Paris 7, CNRS, Paris, France.

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November 2020

Identification of a metabolic, transcriptomic and molecular signature of PNPLA3-mediated acceleration of steatohepatitis.

Authors:
Bubu A Banini Divya P Kumar Sophie Cazanave Mulugeta Seneshaw Faridoddin Mirshahi Prasanna K Santhekadur Liangsu Wang Hong Ping Guan Abdul Oseini Cristina Alonso Pierre Bedossa Srinivas V Koduru Hae-Ki Min Arun J Sanyal

Hepatology 2020 Nov 1. Epub 2020 Nov 1.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA.

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November 2020

The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease.

Authors:
Timothy Hardy Kristy Wonders Ramy Younes Guruprasad P Aithal Rocio Aller Michael Allison Pierre Bedossa Fay Betsou Jerome Boursier M Julia Brosnan Alastair Burt Jeremy Cobbold Helena Cortez-Pinto Chris P Day Jean-Francois Dufour Mattias Ekstedt Sven Francque Stephen Harrison Luca Miele Patrik Nasr George Papatheodoridis Salvatore Petta Dina Tiniakos Richard Torstenson Luca Valenti Adriaan G Holleboom Hannele Yki-Jarvinen Andreas Geier Manuel Romero-Gomez Vlad Ratziu Elisabetta Bugianesi Jörn M Schattenberg Quentin M Anstee

Contemp Clin Trials 2020 Nov 9;98:106175. Epub 2020 Oct 9.

Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom. Electronic address:

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November 2020

A randomised, double-blind, placebo-controlled, multi-centre, dose-range, proof-of-concept, 24-week treatment study of lanifibranor in adult subjects with non-alcoholic steatohepatitis: Design of the NATIVE study.

Authors:
Francque Sven M Bedossa Pierre Abdelmalek Manal F Anstee Quentin M Bugianesi Elisabetta Ratziu Vlad Huot-Marchand Philippe Scherrer Bruno Junien Jean-Louis Broqua Pierre Abitbol Jean-Louis

Contemp Clin Trials 2020 Nov 8;98:106170. Epub 2020 Oct 8.

INVENTIVA S.A., 50 rue de DIJON, 21121 Daix, France.

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November 2020

An Improved qFibrosis Algorithm for Precise Screening and Enrollment into Non-Alcoholic Steatohepatitis (NASH) Clinical Trials.

Authors:
Wei-Qiang Leow Pierre Bedossa Feng Liu Lai Wei Kiat-Hon Lim Wei-Keat Wan Yayun Ren Jason Pik-Eu Chang Chee-Kiat Tan Aileen Wee George Boon-Bee Goh

Diagnostics (Basel) 2020 Aug 28;10(9). Epub 2020 Aug 28.

Duke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore.

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August 2020

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study.

Authors:
Stephen A Harrison Vlad Ratziu Jérôme Boursier Sven Francque Pierre Bedossa Zouher Majd Geneviève Cordonnier Fouad Ben Sudrik Raphael Darteil Roman Liebe Jérémy Magnanensi Yacine Hajji John Brozek Alice Roudot Bart Staels Dean W Hum Sophie Jeannin Megnien Suneil Hosmane Noémie Dam Pierre Chaumat Rémy Hanf Quentin M Anstee Arun J Sanyal

Lancet Gastroenterol Hepatol 2020 11 5;5(11):970-985. Epub 2020 Aug 5.

Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

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November 2020

Fifty years of impact on liver pathology: a history of the Gnomes.

Authors:
Michael Torbenson Valeer Desmet Helmut Denk Francesco Callea Alastair D Burt Stefan G Hübscher Luigi Terracciano Hans-Peter Dienes Zachary D Goodman Pierre Bedossa Ian R Wanless Eve A Roberts Elizabeth M Brunt Andrew D Clouston Annette S H Gouw David Kleiner Peter Schirmacher Dina Tiniakos

Virchows Arch 2020 Jun 30. Epub 2020 Jun 30.

Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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June 2020

The PPAR α/γ Agonist Saroglitazar Improves Insulin Resistance and Steatohepatitis in a Diet Induced Animal Model of Nonalcoholic Fatty Liver Disease.

Authors:
Divya P Kumar Rebecca Caffrey Jonathon Marioneaux Prasanna K Santhekadur Madhavi Bhat Cristina Alonso Srinivas V Koduru Binu Philip Mukul R Jain Suresh R Giri Pierre Bedossa Arun J Sanyal

Sci Rep 2020 06 9;10(1):9330. Epub 2020 Jun 9.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA.

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June 2020

Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.

Authors:
Sophie Cazanave Alexei Podtelezhnikov Kristian Jensen Mulugeta Seneshaw Divya P Kumar Hae-Ki Min Prasanna K Santhekadur Bubu Banini Adolfo Gabriele Mauro Abdul M Oseini Robert Vincent Keith Q Tanis Andrea L Webber Liangsu Wang Pierre Bedossa Faridoddin Mirshahi Arun J Sanyal

Sci Rep 2020 May 15;10(1):8374. Epub 2020 May 15.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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May 2020

Porto-sinusoidal vascular disease. Vascular liver diseases: Position papers from the francophone network for vascular liver diseases, the French Association for the Study of the Liver (AFEF), and ERN-rare liver.

Authors:
Héloïse Giudicelli Pierre-Emmanuel Rautou Valérie Paradis Pierre Bedossa Odile Goria Vincent Lambert Virginia Hernandez-Gea Danielle Dutheil Aurélie Plessier Christophe Bureau Dominique Valla

Clin Res Hepatol Gastroenterol 2020 09 22;44(4):447-451. Epub 2020 Apr 22.

Department of hepatology, DHU Unity, Beaujon hospital, AP-HP, 100, boulevard du Général-Leclerc, 92118 Clichy, France; Inserm, center for research in inflammation, university of Paris, 75018 Paris, France; Reference center of vascular liver diseases European Reference Network (ERN) "Rare-Liver", France; French Network for Rare Liver Diseases (FILFOIE), Saint-Antoine hospital, AP-HP, 184, rue du Faubourg Saint-Antoine, 75012 Paris, France.

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September 2020

Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort.

Authors:
Quentin M Anstee Rebecca Darlay Simon Cockell Marica Meroni Olivier Govaere Dina Tiniakos Alastair D Burt Pierre Bedossa Jeremy Palmer Yang-Lin Liu Guruprasad P Aithal Michael Allison Hannele Yki-Järvinen Michele Vacca Jean-Francois Dufour Pietro Invernizzi Daniele Prati Mattias Ekstedt Stergios Kechagias Sven Francque Salvatore Petta Elisabetta Bugianesi Karine Clement Vlad Ratziu Jörn M Schattenberg Luca Valenti Christopher P Day Heather J Cordell Ann K Daly

J Hepatol 2020 Sep 13;73(3):505-515. Epub 2020 Apr 13.

Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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September 2020

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement.

Authors:
Mohammed Eslam Philip N Newsome Shiv K Sarin Quentin M Anstee Giovanni Targher Manuel Romero-Gomez Shira Zelber-Sagi Vincent Wai-Sun Wong Jean-François Dufour Jörn M Schattenberg Takumi Kawaguchi Marco Arrese Luca Valenti Gamal Shiha Claudio Tiribelli Hannele Yki-Järvinen Jian-Gao Fan Henning Grønbæk Yusuf Yilmaz Helena Cortez-Pinto Claudia P Oliveira Pierre Bedossa Leon A Adams Ming-Hua Zheng Yasser Fouad Wah-Kheong Chan Nahum Mendez-Sanchez Sang Hoon Ahn Laurent Castera Elisabetta Bugianesi Vlad Ratziu Jacob George

J Hepatol 2020 Jul 8;73(1):202-209. Epub 2020 Apr 8.

Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, NSW, Australia. Electronic address:

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July 2020

Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease.

Authors:
Vincenzo Musolino Micaela Gliozzi Federica Scarano Francesca Bosco Miriam Scicchitano Saverio Nucera Cristina Carresi Stefano Ruga Maria Caterina Zito Jessica Maiuolo Roberta Macrì Nicola Amodio Giada Juli Pierfrancesco Tassone Rocco Mollace Rebecca Caffrey Jonathon Marioneaux Ross Walker James Ehrlich Ernesto Palma Carolina Muscoli Pierre Bedossa Daniela Salvemini Vincenzo Mollace Arun J Sanyal

Sci Rep 2020 02 13;10(1):2565. Epub 2020 Feb 13.

Sanyal biotechnology, 800 E Leigh St, Richmond, VA, 23219, USA.

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February 2020

Performance of the PRO-C3 collagen neo-epitope biomarker in non-alcoholic fatty liver disease.

Authors:
Marie Boyle Dina Tiniakos Jorn M Schattenberg Vlad Ratziu Elisabetta Bugianessi Salvatore Petta Claudia P Oliveira Olivier Govaere Ramy Younes Stuart McPherson Pierre Bedossa Mette J Nielsen Morten Karsdal Diana Leeming Stuart Kendrick Quentin M Anstee

JHEP Rep 2019 Sep 4;1(3):188-198. Epub 2019 Jul 4.

Newcastle Liver Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

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September 2019

FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study.

Authors:
Philip N Newsome Magali Sasso Jonathan J Deeks Angelo Paredes Jérôme Boursier Wah-Kheong Chan Yusuf Yilmaz Sébastien Czernichow Ming-Hua Zheng Vincent Wai-Sun Wong Michael Allison Emmanuel Tsochatzis Quentin M Anstee David A Sheridan Peter J Eddowes Indra N Guha Jeremy F Cobbold Valérie Paradis Pierre Bedossa Véronique Miette Céline Fournier-Poizat Laurent Sandrin Stephen A Harrison

Lancet Gastroenterol Hepatol 2020 04 3;5(4):362-373. Epub 2020 Feb 3.

Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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April 2020

Erratum: FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice.

Authors:
Timothy D Rohrbach Amon Asgharpour Melissa A Maczis David Montefusco L Ashley Cowart Pierre Bedossa Arun J Sanyal Sarah Spiegel

J Lipid Res 2020 Feb;61(2):267

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February 2020

The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma.

Authors:
Nicolas Poté Jérôme Cros Samira Laouirem Jérôme Raffenne Magda Negrão Miguel Albuquerque Pierre Bedossa Miguel Godinho Ferreira Slimane Ait Si Ali Rita Fior Valérie Paradis

Liver Int 2020 04 23;40(4):956-967. Epub 2020 Jan 23.

Department of Pathology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Clichy, France.

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April 2020

Cenicriviroc for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis: AURORA Phase 3 study design.

Authors:
Quentin M Anstee Brent A Neuschwander-Tetri Vincent Wai-Sun Wong Manal F Abdelmalek Zobair M Younossi Jiacheng Yuan Maria Lucia Pecoraro Star Seyedkazemi Laurent Fischer Pierre Bedossa Zachary Goodman Naim Alkhouri Frank Tacke Arun Sanyal

Contemp Clin Trials 2020 02 24;89:105922. Epub 2019 Dec 24.

Virginia Commonwealth University, 1201 East Marshall Street, Richmond, VA 23298, USA.

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February 2020