Pier Giuseppe Pelicci

Pier Giuseppe Pelicci

UNVERIFIED PROFILE

Are you Pier Giuseppe Pelicci?   Register this Author

Register author
Pier Giuseppe Pelicci

Pier Giuseppe Pelicci

Publications by authors named "Pier Giuseppe Pelicci"

Are you Pier Giuseppe Pelicci?   Register this Author

100Publications

2288Reads

9Profile Views

Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation.

Mol Oncol 2019 Oct 5;13(10):2033-2048. Epub 2019 Sep 5.

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/1878-0261.12567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763782PMC
October 2019

Modeling cell proliferation in human acute myeloid leukemia xenografts.

Bioinformatics 2019 Sep;35(18):3378-3386

Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btz063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748761PMC
September 2019

Human cord blood (hCB)-CD34+ humanized mice fail to reject human acute myeloid leukemia cells.

PLoS One 2019 19;14(9):e0217345. Epub 2019 Sep 19.

Department of Experimental Oncology at the IEO, European Institute of Oncology IRCCS, Milan, Italy.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217345PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752751PMC
September 2019

Tumor mutational burden quantification from targeted gene panels: major advancements and challenges.

J Immunother Cancer 2019 Jul 15;7(1):183. Epub 2019 Jul 15.

Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139, Milan, Italy.

View Article

Download full-text PDF

Source
https://jitc.biomedcentral.com/articles/10.1186/s40425-019-0
Publisher Site
http://dx.doi.org/10.1186/s40425-019-0647-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631597PMC
July 2019

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis.

Cancer Cell 2019 May 25;35(5):798-815.e5. Epub 2019 Apr 25.

Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, via Adamello 16, 20139 Milan, Italy; Department of Biosciences, University of Milan, 20100 Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15356108193015
Publisher Site
http://dx.doi.org/10.1016/j.ccell.2019.03.007DOI Listing
May 2019

p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.

Cell Rep 2019 01;26(3):624-638.e8

IEO, European Institute of Oncology IRCCS, Department of Experimental Oncology, Via Adamello 16, 20139 Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20142 Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.12.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334229PMC
January 2019

Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology.

Clin Epigenetics 2018 11 16;10(1):143. Epub 2018 Nov 16.

Department of Biomolecular Sciences, Molecular Pathology Laboratory "PaoLa", University of Urbino "Carlo Bo", Via Arco d'Augusto 2, 61032, Fano, PU, Italy.

View Article

Download full-text PDF

Source
https://clinicalepigeneticsjournal.biomedcentral.com/article
Publisher Site
http://dx.doi.org/10.1186/s13148-018-0576-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240272PMC
November 2018

The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II.

Autophagy 2018 6;14(12):2117-2138. Epub 2018 Sep 6.

a Department of Life Sciences , University of Siena , Siena , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2018.1505153DOI Listing
September 2018

Glucose and Lactate Miniaturized Biosensors for SECM-Based High-Spatial Resolution Analysis: A Comparative Study.

ACS Sens 2017 Sep 24;2(9):1310-1318. Epub 2017 Aug 24.

Chemistry Department "Giacomo Ciamician", University of Bologna , Via Selmi 2, 40126 Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acssensors.7b00324DOI Listing
September 2017

Molecular mechanisms of asymmetric divisions in mammary stem cells.

EMBO Rep 2016 12 21;17(12):1700-1720. Epub 2016 Nov 21.

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201643021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283594PMC
December 2016

P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan.

Aging Cell 2016 06 10;15(3):446-54. Epub 2016 Mar 10.

Experimental Oncology Department, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854904PMC
June 2016

Peak shape clustering reveals biological insights.

BMC Bioinformatics 2015 Oct 28;16:349. Epub 2015 Oct 28.

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-015-0787-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625869PMC
October 2015

Calcite Single Crystals as Hosts for Atomic-Scale Entrapment and Slow Release of Drugs.

Adv Healthc Mater 2015 Jul 1;4(10):1510-6. Epub 2015 Jun 1.

Dipartimento di Chimica "Giacomo Ciamician", Alma Mater Studiorum Università di Bologna, via Selmi 2, 40126, Bologna, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adhm.201500170DOI Listing
July 2015

Maintaining epithelial stemness with p63.

Sci Signal 2015 Jul 28;8(387):re9. Epub 2015 Jul 28.

Biochemistry Laboratory, Istituto Dermopatico dell'Immacolata-Istituto di Ricovero e Cura a Carattere Scientifico (IDI-IRCCS), c/o Department of Experimental Medicine and Biochemical Sciences, University of Rome "Tor Vergata," 00133 Rome, Italy. Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aaa1033DOI Listing
July 2015

The Combination of the PARP Inhibitor Rucaparib and 5FU Is an Effective Strategy for Treating Acute Leukemias.

Mol Cancer Ther 2015 Apr 9;14(4):889-98. Epub 2015 Feb 9.

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy. Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-14-0276DOI Listing
April 2015

p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling.

Proc Natl Acad Sci U S A 2015 Mar 4;112(11):3499-504. Epub 2015 Mar 4.

Biochemistry Laboratory, Istituto Dermopatico dell'Immacolata, Istituto di Ricovero e Cura a Carattere Scientifico, Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata," 00133 Rome, Italy; Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1500762112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372004PMC
March 2015

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.

Genome Med 2014 10;6(6):44. Epub 2014 Jun 10.

Center for Genomic Science of IIT@SEMM, Istituto Italiano di Tecnologia, 20139 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gm563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085541PMC
February 2015

The genomic and epigenomic landscapes of AML.

Semin Hematol 2014 Oct 26;51(4):259-72. Epub 2014 Aug 26.

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy; Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.seminhematol.2014.08.007DOI Listing
October 2014

An intrabody specific for the nucleophosmin carboxy-terminal mutant and fused to a nuclear localization sequence binds its antigen but fails to relocate it in the nucleus.

Biotechnol Rep (Amst) 2014 Sep 27;3:27-33. Epub 2014 May 27.

Department of Biomedical Sciences and Engineering, University of Nova Gorica, Glavni Trg 9, SI-5261 Vipava, Slovenia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.btre.2014.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466097PMC
September 2014

PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples.

Epigenetics Chromatin 2014 5;7:18. Epub 2014 Aug 5.

Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Molecular Pathology Lab. 'PaoLa', Via Arco d'Augusto, 2, Fano 61032, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-8935-7-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124777PMC
August 2014

DNA damage response in adult stem cells.

Blood Cells Mol Dis 2014 Apr 28;52(4):147-51. Epub 2014 Jan 28.

Department of Experimental Oncology, European Institute of Oncology, IEO, 20141 Milan, Italy; Dipartimento di Medicina, Chirurgia e Odontoiatria, Università degli Studi di Milano, 20122 Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcmd.2013.12.005DOI Listing
April 2014

Maspin expression and melanoma progression: a matter of sub-cellular localization.

Mod Pathol 2014 Mar 13;27(3):412-9. Epub 2013 Sep 13.

Medical Oncology of Melanoma Unit, Division of Medical Oncology, European Institute of Oncology, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2013.157DOI Listing
March 2014

Next-generation sequencing and DNA replication in human cells: the future has arrived.

Future Oncol 2014 Mar;10(4):683-93

Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon.13.182DOI Listing
March 2014

p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics.

J Leukoc Biol 2014 Feb 27;95(2):285-92. Epub 2013 Sep 27.

1.University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0313178DOI Listing
February 2014

A non-redundant function of cyclin E1 in hematopoietic stem cells.

Cell Cycle 2013 Dec 25;12(23):3663-72. Epub 2013 Sep 25.

Center for Genomic Science of IIT@SEMM; Istituto Italiano di Tecnologia (IIT); Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.26584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903717PMC
December 2013

Obesity increases the incidence of distant metastases in oestrogen receptor-negative human epidermal growth factor receptor 2-positive breast cancer patients.

Eur J Cancer 2013 Nov 15;49(17):3588-97. Epub 2013 Aug 15.

Division of Medical Oncology, Istituto Europeo di Oncologia, Milan, Italy; Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2013.07.016DOI Listing
November 2013

Sequence-specific double strand breaks trigger P-TEFb-dependent Rpb1-CTD hyperphosphorylation.

Mutat Res 2013 Sep 29;749(1-2):21-7. Epub 2013 Jul 29.

Department of Biology, University of Naples 'Federico II', Naples, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mrfmmm.2013.07.005DOI Listing
September 2013

Is PML a Tumor Suppressor?

Front Oncol 2013 9;3:174. Epub 2013 Jul 9.

Department of Experimental Oncology, European Institute of Oncology , Milan , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2013.00174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705425PMC
July 2013

TRIM proteins in cancer.

Adv Exp Med Biol 2012 ;770:77-91

Department of Experimental Oncology, European Institute of Oncology, IEO, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4614-5398-7_6DOI Listing
June 2013

The other face of ROS: a driver of stem cell expansion in colorectal cancer.

Cell Stem Cell 2013 Jun;12(6):635-6

Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19345909130021
Publisher Site
http://dx.doi.org/10.1016/j.stem.2013.05.023DOI Listing
June 2013

Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgene.

Aging Cell 2013 Apr 10;12(2):177-83. Epub 2013 Jan 10.

Department of Experimental Oncology, European Institute of Oncology, Via Adamello 16, Milan, 20139, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141878PMC
April 2013

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.

Blood 2013 Apr 25;121(17):3459-68. Epub 2013 Feb 25.

Department of Experimental Oncology at the IFOM-IEO Campus, European Institute of Oncology, via Adamello 16, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-10-461988DOI Listing
April 2013

A computational platform for robotized fluorescence microscopy (II): DNA damage, replication, checkpoint activation, and cell cycle progression by high-content high-resolution multiparameter image-cytometry.

Cytometry A 2013 Apr 5;83(4):344-55. Epub 2013 Mar 5.

Department of Experimental Oncology, European Institute of Oncology, IFOM-IEO Campus for Oncogenomics, Milan 20139, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cyto.a.22265DOI Listing
April 2013

A computational platform for robotized fluorescence microscopy (I): high-content image-based cell-cycle analysis.

Cytometry A 2013 Apr 5;83(4):333-43. Epub 2013 Mar 5.

Department of Experimental Oncology, European Institute of Oncology, IFOM-IEO Campus for Oncogenomics, Milano 20139, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cyto.a.22266DOI Listing
April 2013

DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions.

Proc Natl Acad Sci U S A 2013 Mar 15;110(10):3931-6. Epub 2013 Feb 15.

Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1213394110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593901PMC
March 2013

Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging.

Hippocampus 2012 Dec 18;22(12):2249-59. Epub 2012 Jun 18.

Section of Behavioral Neuroscience, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hipo.22042DOI Listing
December 2012

Genomics of acute myeloid leukemia: the next generation.

Front Oncol 2012 1;2:40. Epub 2012 May 1.

Department of Experimental Oncology, European Institute of Oncology Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2012.00040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364462PMC
August 2012

Electrochemical study of hydrogen peroxide formation in isolated mitochondria.

Bioelectrochemistry 2012 Jun 3;85:21-8. Epub 2011 Dec 3.

Experimental Oncology Dept. European Institute of Oncology, Via Adamello 16, 20139 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bioelechem.2011.11.005DOI Listing
June 2012

The emerging role of p53 in stem cells.

Trends Mol Med 2012 Jan 7;18(1):6-12. Epub 2011 Sep 7.

Istituto Europeo di Oncologia (IEO), Department of Experimental Oncology at the IFOM-IEO Campus, Via Adamello 16, 20139 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmed.2011.08.002DOI Listing
January 2012

Inhibition of epithelial-to-mesenchimal transition: a novel tumor suppressor function of p53?

Cell Cycle 2011 Aug 15;10(16):2616-7. Epub 2011 Aug 15.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.10.16.16543DOI Listing
August 2011

p66Shc is a negative regulator of FcεRI-dependent signaling in mast cells.

J Immunol 2011 May 23;186(9):5095-106. Epub 2011 Mar 23.

Department of Evolutionary Biology, University of Siena, 53100 Siena, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1001391DOI Listing
May 2011

Heating cancer stem cells to reduce tumor relapse.

Breast Cancer Res 2011 May 6;13(3):305. Epub 2011 May 6.

European Institute of Oncology, Department of Experimental Oncology, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/bcr2847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218927PMC
May 2011

The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone.

Biochemistry 2011 Apr 22;50(14):2780-9. Epub 2011 Mar 22.

Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi101835jDOI Listing
April 2011

A Role for PML in Innate Immunity.

Genes Cancer 2011 Jan;2(1):10-9

Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1947601911402682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111006PMC
January 2011

Differential cytogenomics and miRNA signature of the Acute Myeloid Leukaemia Kasumi-1 cell line CD34+38- compartment.

Leuk Res 2010 Oct 12;34(10):1287-95. Epub 2010 Mar 12.

Genetica Medica, Dipartimento di Medicina, Chirurgia e Odontoiatria, Università di Milano, Via A di Rudinì 8, 20142 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.leukres.2010.02.012DOI Listing
October 2010

Histone deacetylases and epigenetic therapies of hematological malignancies.

Pharmacol Res 2010 Jul 26;62(1):18-34. Epub 2010 Feb 26.

DAC-Genextra Group, Via Adamello 16, 20100 Milan, Italy; IFOM-IEO-Campus, Via Adamello 16, 20100 Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2010.02.010DOI Listing
July 2010

Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice.

Exp Gerontol 2010 May 18;45(5):343-50. Epub 2010 Jan 18.

Section of Behavioural Neurosciences, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exger.2010.01.010DOI Listing
May 2010