Publications by authors named "Pichai Raman"

43Publications

RET receptor expression and interaction with TRK receptors in neuroblastomas.

Oncol Rep 2020 Jul 15;44(1):263-272. Epub 2020 Apr 15.

Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia and The University of Pennsylvania, Philadelphia, PA 19104‑4302, USA.

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http://dx.doi.org/10.3892/or.2020.7583DOI Listing
July 2020

Immunogenicity and Immune Silence in Human Cancer.

Front Immunol 2020 6;11:69. Epub 2020 Mar 6.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fimmu.2020.00069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092187PMC
March 2020

CAMKV Is a Candidate Immunotherapeutic Target in Amplified Neuroblastoma.

Front Oncol 2020 6;10:302. Epub 2020 Mar 6.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fonc.2020.00302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069022PMC
March 2020

Diagnosing Cornelia de Lange syndrome and related neurodevelopmental disorders using RNA sequencing.

Genet Med 2020 May 8;22(5):927-936. Epub 2020 Jan 8.

Genomics Center, Al Jalila Children's Specialty Hospital, Dubai, UAE.

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http://dx.doi.org/10.1038/s41436-019-0741-5DOI Listing
May 2020

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.

Cell Rep 2019 11;29(6):1675-1689.e9

Division of Oncology, Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-4318, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.09.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880934PMC
November 2019

A comparison of survival analysis methods for cancer gene expression RNA-Sequencing data.

Cancer Genet 2019 06 12;235-236:1-12. Epub 2019 Apr 12.

Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, United States; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, United States; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2019.04.004DOI Listing
June 2019

Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.

Mol Cancer Ther 2019 07 9;18(7):1195-1204. Epub 2019 May 9.

Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606392PMC
July 2019

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.

Dev Cell 2019 04 28;49(1):10-29. Epub 2019 Mar 28.

Department of Biomedical Informatics, University of Cincinnati College of Medicine, and Cincinnati Children's Hospital Medical Center, Division of Biomedical Informatics, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.devcel.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616346PMC
April 2019

An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.

Sci Transl Med 2019 03;11(483)

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.aau9732DOI Listing
March 2019

Pediatric Somatic Tumor Sequencing Identifies Underlying Cancer Predisposition.

JCO Precis Oncol 2019 16;3. Epub 2019 Dec 16.

Division of Oncology, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/po.19.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416724PMC
December 2019

Pancreatic cancer survival analysis defines a signature that predicts outcome.

PLoS One 2018 9;13(8):e0201751. Epub 2018 Aug 9.

School of Biomedical Engineering, Sciences, and Health Systems, Drexel University, Philadelphia, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201751PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084949PMC
January 2019

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41586-018-0167-2DOI Listing
July 2018

The landscape of genomic alterations across childhood cancers.

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature25480DOI Listing
March 2018

Comprehensive Analysis of Hypermutation in Human Cancer.

Cell 2017 Nov 19;171(5):1042-1056.e10. Epub 2017 Oct 19.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849393PMC
November 2017

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Cancer Cell 2017 09;32(3):295-309.e12

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600520PMC
September 2017

The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma.

J Cell Mol Med 2017 Dec 30;21(12):3224-3230. Epub 2017 Jun 30.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/jcmm.13226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706517PMC
December 2017

Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing.

Immunobiology 2017 07 20;222(7):847-856. Epub 2017 Feb 20.

School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA, 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2017.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719494PMC
July 2017

Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma.

Clin Cancer Res 2017 Apr 11;23(7):1785-1796. Epub 2016 Oct 11.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1131DOI Listing
April 2017

Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.

Nat Commun 2015 Dec 7;6:10028. Epub 2015 Dec 7.

Division of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ncomms10028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686657PMC
December 2015

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.

Cancer Discov 2015 Dec 29;5(12):1282-95. Epub 2015 Oct 29.

Division of Cancer Pathobiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Immunology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Cell & Molecular Biology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Department of Pathology & Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-15-1020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670800PMC
December 2015

FXYD5 is a Marker for Poor Prognosis and a Potential Driver for Metastasis in Ovarian Carcinomas.

Cancer Inform 2015 12;14:113-9. Epub 2015 Oct 12.

School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA, USA.

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http://dx.doi.org/10.4137/CIN.S30565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603440PMC
October 2015

A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis.

Cancer Cell 2015 Nov 17;28(5):599-609. Epub 2015 Oct 17.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643330PMC
November 2015

Crizotinib Synergizes with Chemotherapy in Preclinical Models of Neuroblastoma.

Clin Cancer Res 2016 Feb 5;22(4):948-60. Epub 2015 Oct 5.

Division of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755925PMC
February 2016

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus.

Cancer Res 2015 Aug 22;75(15):3155-66. Epub 2015 Jun 22.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. The Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526355PMC
August 2015

Genomic and functional comparison of mesenchymal stromal cells prepared using two isolation methods.

Cytotherapy 2015 Mar;17(3):262-70

Division of Oncology/Blood and Marrow Transplantation, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA; Divsion of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2014.10.013DOI Listing
March 2015

Masking epistasis between MYC and TGF-β pathways in antiangiogenesis-mediated colon cancer suppression.

J Natl Cancer Inst 2014 Apr 13;106(4):dju043. Epub 2014 Mar 13.

Affiliations of authors: Division of Cancer Pathobiology, Center for Childhood Cancer Research (MD, GST, SH, AT-T) and Center for Biomedical Informatics (PR), Children's Hospital of Philadelphia, Philadelphia, PA; Cancer Biology Graduate Program (JC, EKD, AT-T) and Department of Pathology & Laboratory Medicine (AT-T), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Division of Experimental Pathology, Beth Israel Deaconess Medical Center (JL) and Department of Medical Oncology, Dana-Farber Cancer Institute (AB), Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1093/jnci/dju043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982891PMC
April 2014

The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loop.

Blood 2013 Dec 29;122(26):4220-9. Epub 2013 Oct 29.

Division of Cancer Pathobiology/Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA;

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http://dx.doi.org/10.1182/blood-2012-12-473090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868926PMC
December 2013

Compound set enrichment: a novel approach to analysis of primary HTS data.

J Chem Inf Model 2010 Dec 12;50(12):2067-78. Epub 2010 Nov 12.

Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1, Novartis Campus, CH-4056 Basel, Switzerland, and 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1021/ci100203eDOI Listing
December 2010

A model-based approach for mining membrane protein crystallization trials.

Bioinformatics 2006 Jul;22(14):e40-8

Department of Computer Science and Engineering, Ohio State University, USA.

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http://dx.doi.org/10.1093/bioinformatics/btl225DOI Listing
July 2006