Publications by authors named "Phyllis A Gimotty"

100Publications

In-Hospital Complications and Readmission in Patients with Hemophilia Undergoing Hip or Knee Arthroplasty.

JB JS Open Access 2020 Apr-Jun;5(2):e0085. Epub 2020 Jun 5.

Departments of Biostatistics, Epidemiology and Informatics (M.L. and P.A.G.), Medicine (R.V. and A.C.), and Pathology and Laboratory Medicine (A.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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June 2020

ASO Author Reflection: Sentinel Lymph Node Biopsy in Thin Melanoma.

Ann Surg Oncol 2020 Dec 24;27(Suppl 3):901-902. Epub 2020 Aug 24.

Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, USA.

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December 2020

Survival Outcomes Following Lymph Node Biopsy in Thin Melanoma-A Propensity-Matched Analysis.

Ann Surg Oncol 2020 Aug 10. Epub 2020 Aug 10.

Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, USA.

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August 2020

Urethral involvement is associated with higher mortality and local recurrence in vulvar melanoma: a single institutional experience.

Hum Pathol 2020 Oct 20;104:1-8. Epub 2020 Jul 20.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. Electronic address:

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October 2020

Neoadjuvant Versus Adjuvant Immune Checkpoint Blockade in the Treatment of Clinical Stage III Melanoma.

Ann Surg Oncol 2020 Aug 2;27(8):2915-2926. Epub 2020 Jan 2.

Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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August 2020

Correction to: Characteristics Associated with Pathologic Nodal Burden in Patients Presenting with Clinical Melanoma Nodal Metastasis.

Ann Surg Oncol 2019 12;26(Suppl 3):893

Department of Surgery, Division of Endocrine and Oncologic Surgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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December 2019

Characteristics Associated with Pathologic Nodal Burden in Patients Presenting with Clinical Melanoma Nodal Metastasis.

Ann Surg Oncol 2019 11 7;26(12):3962-3971. Epub 2019 Aug 7.

Department of Surgery, Division of Endocrine and Oncologic Surgery, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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November 2019

Survival Outcomes of Patients with Clinical Stage III Melanoma in the Era of Novel Systemic Therapies.

Ann Surg Oncol 2019 Dec 3;26(13):4621-4630. Epub 2019 Jul 3.

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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December 2019

Stromal inflammatory cells are associated with poorer prognosis in primary cutaneous melanoma.

Hum Pathol 2019 06 6;88:78-86. Epub 2019 Apr 6.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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June 2019

Statistical methods for building better biomarkers of chronic kidney disease.

Stat Med 2019 05 21;38(11):1903-1917. Epub 2019 Jan 21.

Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

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May 2019

Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer.

Oncotarget 2018 Feb 15;9(10):8985-8998. Epub 2017 Dec 15.

Department of Otorhinolaryngology, Head and Neck Surgery, The University of Pennsylvania, Philadelphia, PA, USA.

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February 2018

Histological immune response patterns in sentinel lymph nodes involved by metastatic melanoma and prognostic significance.

J Cutan Pathol 2018 Jun 23;45(6):377-386. Epub 2018 Mar 23.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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June 2018

Revascularization strategies and in-hospital management in acute coronary syndromes complicated by hemophilia A or hemophilia B.

Blood Coagul Fibrinolysis 2017 Dec;28(8):650-657

aDepartment of Medicine, University of Pennsylvania Health SystembDepartment of Biostatistics, Epidemiology and informatics, University of PennsylvaniacCardiovascular Division, Penn Presbyterian Medical CenterdDivision of Hematology/Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA*Phyllis A. Gimotty and Patrick F. Fogarty contributed equally to this article.†Address where work was carried out. Present address: 500 Arcola Road, Collegeville, PA 19426, USA.

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December 2017

Barriers to generating PDX models of HPV-related head and neck cancer.

Laryngoscope 2017 12 31;127(12):2777-2783. Epub 2017 May 31.

Department of Otorhinolaryngology-Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.

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December 2017

Oncogenic RAS Regulates Long Noncoding RNA in Human Cancer.

Cancer Res 2017 07 4;77(14):3745-3757. Epub 2017 May 4.

Center for Research on Reproduction & Women's Health, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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July 2017

Contemporary Trends in Radiation Oncology Resident Research.

Int J Radiat Oncol Biol Phys 2016 11 11;96(4):915-918. Epub 2016 Aug 11.

Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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November 2016

Miscoding of Melanoma Thickness in SEER: Research and Clinical Implications.

J Invest Dermatol 2016 11 25;136(11):2168-2172. Epub 2016 Jun 25.

Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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November 2016

Immune checkpoint blockade reveals the stimulatory capacity of tumor-associated CD103(+) dendritic cells in late-stage ovarian cancer.

Oncoimmunology 2016 Aug 13;5(8):e1185583. Epub 2016 May 13.

Division of Gynecologic Oncology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA; Ovarian Cancer Research Center, The University of Pennsylvania, Philadelphia, PA, USA.

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August 2016

JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers.

Cancer Res 2016 09 3;76(18):5538-49. Epub 2016 Aug 3.

Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania. The Wistar Institute, Philadelphia, Pennsylvania. VA Medical Center, Philadelphia, Pennsylvania.

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September 2016

A rapid pro-hemostatic approach to overcome direct oral anticoagulants.

Nat Med 2016 08 25;22(8):924-32. Epub 2016 Jul 25.

Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia (CHOP), Philadelphia, Pennsylvania, USA.

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August 2016

A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia.

JCI Insight 2016 Jun;1(9)

Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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June 2016

A Modified Integrated Genetic Model for Risk Prediction in Younger Patients with Acute Myeloid Leukemia.

PLoS One 2016 6;11(4):e0153016. Epub 2016 Apr 6.

Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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August 2016

American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine.

CA Cancer J Clin 2016 09 19;66(5):370-4. Epub 2016 Jan 19.

Professor, Life Science, Arizona State University, Tempe, AZ; Professor, Laboratory Medicine and Pathology, Mayo Clinic School of Medicine, Rochester, MN; Chief Medical Officer, National Biomarker Development Alliance, Scottsdale, AZ.

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September 2016

Diagnostic accuracy of rapid immunoassays for heparin-induced thrombocytopenia. A systematic review and meta-analysis.

Thromb Haemost 2016 05 14;115(5):1044-55. Epub 2016 Jan 14.

Adam Cuker, MD, MS, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA, Tel.: +1 215 615 6555, Fax: +1 215 615 6599, E-mail:

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May 2016

CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer.

Cancer Immunol Res 2015 Nov 2;3(11):1257-68. Epub 2015 Jul 2.

The University of New Mexico Cancer Center, Albuquerque, New Mexico.

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November 2015

Radiofrequency Ablation Is Associated With Decreased Neoplastic Progression in Patients With Barrett's Esophagus and Confirmed Low-Grade Dysplasia.

Gastroenterology 2015 Sep 24;149(3):567-76.e3; quiz e13-4. Epub 2015 Apr 24.

Department of Medicine, Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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September 2015

DNMT3A Mutational Status Affects the Results of Dose-Escalated Induction Therapy in Acute Myelogenous Leukemia.

Clin Cancer Res 2015 Apr 21;21(7):1614-20. Epub 2015 Jan 21.

Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.

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April 2015

IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment.

Am J Cancer Res 2014 15;4(1):29-41. Epub 2014 Jan 15.

Division of Gastroenterology, Department of Medicine, University of Pennsylvania Philadelphia, PA, USA ; Abramson Cancer Center, University of Pennsylvania Philadelphia, PA, USA.

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January 2014

Lymphatic invasion as a prognostic biomarker in primary cutaneous melanoma.

Methods Mol Biol 2014 ;1102:275-86

Department of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, Philadelphia, PA, USA.

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June 2014

Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis.

Blood 2012 Nov 18;120(20):4160-7. Epub 2012 Sep 18.

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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November 2012

Lymphatic invasion is independently prognostic of metastasis in primary cutaneous melanoma.

Clin Cancer Res 2012 Jan 17;18(1):229-37. Epub 2011 Nov 17.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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January 2012

Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission.

Cancer Immunol Immunother 2012 May 22;61(5):629-41. Epub 2011 Oct 22.

Department of Obstetrics and Gynecology and Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

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May 2012

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.

Nature 2011 Jul 13;475(7355):226-30. Epub 2011 Jul 13.

Ovarian Cancer Research Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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July 2011

Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas.

Cell Cycle 2011 Jun 15;10(12):2008-16. Epub 2011 Jun 15.

Department of Otorhinolaryngology–Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.

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June 2011

Sunscreen and melanoma: what is the evidence?

J Clin Oncol 2011 Jan 6;29(3):249-50. Epub 2010 Dec 6.

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January 2011

Prognostication in thin cutaneous melanomas.

Arch Pathol Lab Med 2010 Dec;134(12):1758-63

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, 19104-6021, USA.

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December 2010

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation.

J Clin Invest 2010 Aug 19;120(8):2699-714. Epub 2010 Jul 19.

Abramson Family Cancer Research Institute, Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160, USA

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August 2010

Therapeutic effect of sentinel lymph node biopsy in melanoma remains an open question.

J Clin Oncol 2009 Sep 10;27(26):4236-8. Epub 2009 Aug 10.

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.

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September 2009

Intraepithelial T cells and tumor proliferation: impact on the benefit from surgical cytoreduction in advanced serous ovarian cancer.

Cancer 2009 Jul;115(13):2891-902

Department of Obstetrics and Gynecology, Ovarian Cancer Research Center, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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July 2009

CXCR3 expression is associated with poor survival in breast cancer and promotes metastasis in a murine model.

Mol Cancer Ther 2009 Mar 10;8(3):490-8. Epub 2009 Mar 10.

University of Maryland Greenebaum Cancer Center, Department of Pathology, School of Medicine, 9th Floor, 655 West Baltimore Street, Baltimore, MD 21201, USA.

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March 2009

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia.

J Clin Invest 2008 Sep;118(9):3181-94

Division of Hematology-Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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September 2008

Effect of guidelines on primary care physician use of PSA screening: results from the Community Tracking Study Physician Survey.

Med Decis Making 2008 Sep-Oct;28(5):681-9. Epub 2008 Jun 12.

Division of General Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA.

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January 2009

Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis.

Hum Pathol 2008 Jun 28;39(6):901-9. Epub 2008 Apr 28.

Department of Pathology and Laboratory Medicine, and the Melanoma Program of the Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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June 2008

Varying coefficient model with unknown within-subject covariance for analysis of tumor growth curves.

Biometrics 2008 Dec 7;64(4):1023-31. Epub 2008 Feb 7.

Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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December 2008

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.

Nat Med 2008 Jan 6;14(1):28-36. Epub 2008 Jan 6.

Center for Research on Ovarian Cancer Early Detection and Cure, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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January 2008

Immune prognostic factors in ovarian cancer: lessons from translational research.

Dis Markers 2007 ;23(5-6):445-52

Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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March 2008