Phillip E Melton

Phillip E Melton

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Phillip E Melton

Phillip E Melton

Publications by authors named "Phillip E Melton"

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Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease.

J Clin Endocrinol Metab 2019 Jul;104(7):3012-3024

Curtin/UWA Centre for Genetic Origins of Health and Disease, School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.

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http://dx.doi.org/10.1210/jc.2018-02076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555851PMC
July 2019

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

J Allergy Clin Immunol 2019 Jun 21;143(6):2062-2074. Epub 2018 Dec 21.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183278
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http://dx.doi.org/10.1016/j.jaci.2018.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556405PMC
June 2019

Genetic influence on scar height and pliability after burn injury in individuals of European ancestry: A prospective cohort study.

Burns 2019 05 27;45(3):567-578. Epub 2018 Dec 27.

Burn Injury Research Unit, School of Biomedical Sciences, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1016/j.burns.2018.10.027DOI Listing
May 2019

Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes.

J Hypertens 2019 May;37(5):997-1011

The Curtin/UWA Centre for Genetic Origins of Health and Disease, School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University.

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http://dx.doi.org/10.1097/HJH.0000000000002023DOI Listing
May 2019

Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts.

BMC Med Genet 2019 05 3;20(1):69. Epub 2019 May 3.

The Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health Sciences, Curtin University and Faculty of Health and Medical Sciences, M409 The University of Western Australia, 35 Stirling Hwy, Crawley, 6009, Western Australia.

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https://bmcmedgenet.biomedcentral.com/articles/10.1186/s1288
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http://dx.doi.org/10.1186/s12881-019-0808-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499942PMC
May 2019

Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes.

Cancers (Basel) 2019 Apr 10;11(4). Epub 2019 Apr 10.

School of Pharmacy and Biomedical Sciences, and Curtin Health Innovation Research Institute, Curtin University, Bentley, WA 6102, Australia.

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http://dx.doi.org/10.3390/cancers11040516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521159PMC
April 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies , , and as Novel Candidate Risk Genes.

Front Genet 2019 19;10:227. Epub 2019 Mar 19.

The Curtin UWA Centre for Genetic Origins of Health and Disease, Faculty of Health and Medical Sciences, Curtin University, The University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.3389/fgene.2019.00227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434177PMC
March 2019

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.

EBioMedicine 2018 Dec 13;38:206-216. Epub 2018 Nov 13.

Center for Life Course Health Research, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Medical Research Centre (MRC) Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183048
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http://dx.doi.org/10.1016/j.ebiom.2018.10.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306313PMC
December 2018

Epigenetics, heritability and longitudinal analysis.

BMC Genet 2018 09 17;19(Suppl 1):77. Epub 2018 Sep 17.

Curtin/UWA Centre for Genetic Origins of Health and Disease, School of Pharmacy and Biomedical Sciences, Curtin University and the University of Western Australia, 35 Stirling Hwy. (M409), Crawley, WA, 6009, Australia.

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http://dx.doi.org/10.1186/s12863-018-0648-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156830PMC
September 2018

Whole genome sequencing of 91 multiplex schizophrenia families reveals increased burden of rare, exonic copy number variation in schizophrenia probands and genetic heterogeneity.

Schizophr Res 2018 Jul 24;197:337-345. Epub 2018 Feb 24.

Centre for Clinical Research in Neuropsychiatry, School of Psychiatry and Clinical Neurosciences, University of Western Australia, MRF Building, 50 Murray Street, Perth 6000, Australia; Cooperative Research Centre for Mental Health, Carlton, South Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2018.02.034DOI Listing
July 2018

Pleiotropy of cardiometabolic syndrome with obesity-related anthropometric traits determined using empirically derived kinships from the Busselton Health Study.

Hum Genet 2018 Jan 27;137(1):45-53. Epub 2017 Nov 27.

Centre for Genetic Origins of Health and Disease, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1007/s00439-017-1856-xDOI Listing
January 2018

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Hum Mol Genet 2017 10;26(20):4067-4085

MRC Integrative Epidemiology Unit.

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http://dx.doi.org/10.1093/hmg/ddx290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656174PMC
October 2017

Exome array analysis suggests an increased variant burden in families with schizophrenia.

Schizophr Res 2017 07 9;185:9-16. Epub 2016 Dec 9.

Centre for Clinical Research in Neuropsychiatry, School of Psychiatry and Clinical Neurosciences, University of Western Australia, MRF Building, 50 Murray Street, Perth 6000, Australia; Cooperative Research Centre for Mental Health, Carlton, South, Victoria, Australia.

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http://dx.doi.org/10.1016/j.schres.2016.12.007DOI Listing
July 2017

The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.

J Hypertens 2017 01;35(1):132-139

aDepartment of Gynecology and Obstetrics, Haukeland University Hospital bDepartment of Clinical Science, University of Bergen, Bergen, Norway cCentre for Genetic Origins of Health and Disease, University of Western Australia, Perth, Australia dDepartment of Cancer Research and Molecular Medicine, Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim eDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway fSouth Texas Diabetes and Obesity Institute, School of Medicine, University of Texas Rio Grande Valley, Brownsville, Texas, USA gDepartment of Obstetrics and Gynaecology, University of Melbourne, Parkville hPregnancy Research Centre, Department of Maternal-Fetal Medicine, Royal Women's Hospital, Parkville, Victoria iFaculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1097/HJH.0000000000001131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131692PMC
January 2017

Constrained multivariate association with longitudinal phenotypes.

BMC Proc 2016 18;10(Suppl 7):329-332. Epub 2016 Oct 18.

South Texas Diabetes and Obesity Institute, University of Texas Health Science Center, San Antonio, TX 78229 USA ; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104 USA ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 USA.

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http://dx.doi.org/10.1186/s12919-016-0051-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133503PMC
October 2016

Genome-wide transcriptome directed pathway analysis of maternal pre-eclampsia susceptibility genes.

PLoS One 2015 26;10(5):e0128230. Epub 2015 May 26.

Centre for Genetic Origins of Health and Disease, The University of Western Australia, 35 Stirling Highway, Crawley, 6009, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128230PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444079PMC
April 2016

Longitudinal analytical approaches to genetic data.

BMC Genet 2016 Feb 3;17 Suppl 2. Epub 2016 Feb 3.

Centre for Genetic Origins of Health and Disease, University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1186/s12863-015-0312-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895696PMC
February 2016

Effect of recent historical events on migration and isonymic stratification among the Rama Amerindians from Nicaragua.

Hum Biol 2014 ;86(1):37-50

Department of Anthropology, University of Kansas, Lawrence, Kansas, USA.

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http://dx.doi.org/10.3378/027.086.0105DOI Listing
November 2015

Refined phenotyping identifies links between preeclampsia and related diseases in a Norwegian preeclampsia family cohort.

J Hypertens 2015 Nov;33(11):2294-302

aDepartment of Gynecology and Obstetrics, Haukeland University Hospital bDepartment of Clinical Science, University of Bergen, Bergen, Norway cCentre for Genetic Origins of Health and Disease, University of Western Australia, Perth, Australia dCentre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim eDepartment of Obstetrics and Gynecology, Stavanger University Hospital, Stavanger fDepartment of Cancer Research and Molecular Medicine gDepartment of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim hDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway.

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https://insights.ovid.com/crossref?an=00004872-201511000-000
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http://dx.doi.org/10.1097/HJH.0000000000000696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596487PMC
November 2015

Absence of germline mutations in BAP1 in sporadic cases of malignant mesothelioma.

Gene 2015 May 18;563(1):103-5. Epub 2015 Mar 18.

National Centre for Asbestos Related Disease, School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia 6009, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.03.031DOI Listing
May 2015

Bivariate association analysis of longitudinal phenotypes in families.

BMC Proc 2014 17;8(Suppl 1):S90. Epub 2014 Jun 17.

Department of Genetics, Texas Biomedical Research Institute, San Antonio, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143799PMC
December 2014

Evidence of heterogeneity by race/ethnicity in genetic determinants of QT interval.

Epidemiology 2014 Nov;25(6):790-8

From the aDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC; bDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; cCharles Bronfman Institute of Personalized Medicine, Mount Sinai School of Medicine, New York, NY; dCentre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Australia; eDepartment of Biostatistics, University of Washington, Seattle, WA; fInformation Sciences Institute and Computer Science Department, University of Southern California, Marina Del Rey, CA; gDepartment of Epidemiology, University of Washington, Seattle, WA; hCardiovascular Health Research Unit, University of Washington, Seattle, WA; iGroup Health Research Institute, Group Health Cooperative, Seattle, WA; jOffice of Population Genomics, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD; kDepartment of Internal Medicine, Ohio State Medical Center, Columbus, OH; lDivision of Cardiology, George Washington University, Washington, DC; mDepartment of Medicine, Weill Cornell Medical College, New York, NY; nDivision of Cardiovascular Medicine, Stanford University, Stanford, CA; oDivision of Medicine, University of Washington, Seattle, WA; pDivision of Health Services, University of Washington, Seattle, WA; qEpidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, NC; rDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; and sDepartment of Genetics, Texas Biomedical Research Institute, San Antonio, TX.

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http://dx.doi.org/10.1097/EDE.0000000000000168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380285PMC
November 2014

Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns.

BMC Genomics 2014 Nov 18;15:981. Epub 2014 Nov 18.

Centre for the Genetic Origins of Health and Disease (GOHaD), University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1186/1471-2164-15-981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255932PMC
November 2014

Longitudinal data analysis for genetic studies in the whole-genome sequencing era.

Genet Epidemiol 2014 Sep;38 Suppl 1:S74-80

Department of Mathematical Sciences, Worcester Polytechnic Institute, Worcester, Massachusetts, United States of America.

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http://dx.doi.org/10.1002/gepi.21829DOI Listing
September 2014

Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22.

Pregnancy Hypertens 2014 Apr 22;4(2):178-85. Epub 2014 Mar 22.

Centre for Genetic Origins of Health and Disease, The University of Western Australia, Perth, WA 6009, Australia.

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http://dx.doi.org/10.1016/j.preghy.2014.03.005DOI Listing
April 2014

Microevolution, migration, and the population structure of five Amerindian populations from Nicaragua and Costa Rica.

Am J Hum Biol 2013 Jul-Aug;25(4):480-90. Epub 2013 Apr 4.

Centre for Genetic Origins of Health and Disease, University of Western Australia, Crawley, Australia.

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http://dx.doi.org/10.1002/ajhb.22382DOI Listing
November 2013

A genome-wide association study for malignant mesothelioma risk.

Lung Cancer 2013 Oct 1;82(1):1-8. Epub 2013 Jul 1.

Centre for Genetic Origins of Health and Disease, University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.04.018DOI Listing
October 2013

Genome-wide association study of autistic-like traits in a general population study of young adults.

Front Hum Neurosci 2013 11;7:658. Epub 2013 Oct 11.

Centre for Genetic Origins of Health and Disease, University of Western Australia , Perth, WA , Australia.

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http://dx.doi.org/10.3389/fnhum.2013.00658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795398PMC
October 2013

Joint analyses of disease and correlated quantitative phenotypes using next-generation sequencing data.

Genet Epidemiol 2011 ;35 Suppl 1:S67-73

Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.

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http://dx.doi.org/10.1002/gepi.20653DOI Listing
May 2012

Genetic signal maximization using environmental regression.

BMC Proc 2011 Nov 29;5 Suppl 9:S72. Epub 2011 Nov 29.

Department of Genetics, Texas Biomedical Research Institute, PO Box 760549, San Antonio, TX 78253, USA.

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http://dx.doi.org/10.1186/1753-6561-5-S9-S72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287912PMC
November 2011

Large scale mitochondrial sequencing in Mexican Americans suggests a reappraisal of Native American origins.

BMC Evol Biol 2011 Oct 7;11:293. Epub 2011 Oct 7.

Department of Genetics, Texas Biomedical Research Institute, San Antonio, 78227, USA.

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http://dx.doi.org/10.1186/1471-2148-11-293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217880PMC
October 2011

Genetic structure of native circumpolar populations based on autosomal, mitochondrial, and Y chromosome DNA markers.

Am J Phys Anthropol 2010 Sep;143(1):62-74

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245-0549, USA.

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http://dx.doi.org/10.1002/ajpa.21290DOI Listing
September 2010

Mitochondrial DNA diversity in Mennonite communities from the midwestern United States.

Hum Biol 2010 Jun;82(3):267-89

Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://dx.doi.org/10.3378/027.082.0302DOI Listing
June 2010

Biological relationship between Central and South American Chibchan speaking populations: evidence from mtDNA.

Am J Phys Anthropol 2007 May;133(1):753-70

Department of Anthropology, University of Kansas, Lawrence, KS 66045, USA.

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http://dx.doi.org/10.1002/ajpa.20581DOI Listing
May 2007

Biological aging and Cox hazard analysis of mortality trends in a Mennonite community from south-central Kansas.

Am J Hum Biol 2006 May-Jun;18(3):387-401

Department of Anthropology, University of Kansas, Lawrence, 66045, USA.

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http://dx.doi.org/10.1002/ajhb.20514DOI Listing
May 2006