Publications by authors named "Philippe Metellus"

100Publications

Management, functional outcomes and survival in a French multicentric series of 118 adult patients with cerebellar glioblastoma.

J Cancer Res Clin Oncol 2021 Jan 5. Epub 2021 Jan 5.

Department of Neurosurgery, Hospices Civils de Lyon, Hôpital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69667, Bron, France.

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January 2021

A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases.

Cancers (Basel) 2019 May 13;11(5). Epub 2019 May 13.

Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France.

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May 2019

Posterior Fossa Metastasis-Associated Obstructive Hydrocephalus in Adult Patients: Literature Review and Practical Considerations from the Neuro-Oncology Club of the French Society of Neurosurgery.

World Neurosurg 2018 Sep 20;117:271-279. Epub 2018 Jun 20.

Department of Neurosurgery, Sainte-Anne Hospital, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Paris, France; Inserm, U894, IMA-Brain, Centre de Psychiatrie et Neurosciences, Paris, France. Electronic address:

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September 2018

Psychological impact of von Hippel-Lindau genetic screening in patients with a previous history of hemangioblastoma of the central nervous system.

J Psychosoc Oncol 2018 Sep-Oct;36(5):624-634. Epub 2018 May 15.

h Department of Nuclear Medicine , La Timone University Hospital & CERIMED & Inserm UMR1068 Marseille Cancerology Research Center, Institut Paoli-Calmettes, Aix-Marseille University , Marseille , France.

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August 2019

Intracerebral injection of CpG oligonucleotide for patients with de novo glioblastoma-A phase II multicentric, randomised study.

Eur J Cancer 2017 03 28;73:30-37. Epub 2017 Jan 28.

Assistance Publique-Hôpitaux de Paris, Hôpital Avicenne, Service de Neurologie, Bobigny, France; Université Paris 13, UFR de Santé, Médecine et Biologie Humaine, Bobigny, France.

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March 2017

EGFR and KRAS Mutations Predict the Incidence and Outcome of Brain Metastases in Non-Small Cell Lung Cancer.

Int J Mol Sci 2016 Dec 18;17(12). Epub 2016 Dec 18.

Assistance Publique Hôpitaux de Marseille, Multidisciplinary Oncology & Therapeutic Innovations department. Aix Marseille University, Marseille 13015, France.

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December 2016

Successful Insular Glioma Removal in a Deaf Signer Patient During an Awake Craniotomy Procedure.

World Neurosurg 2017 Feb 1;98:883.e1-883.e5. Epub 2016 Sep 1.

Assistance Publique - Hôpitaux de Marseille, Hôpital de la Timone, Marseille, France; Faculté de Médecine, Aix-Marseille Université, Marseille, France; Centre de Résonnance Magnétique Biologique et Médicale, Hôpital de la Timone, CNRS UMR 7339, Marseille, France.

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February 2017

In Vivo Tumour Mapping Using Electrocorticography Alterations During Awake Brain Surgery: A Pilot Study.

Brain Topogr 2016 09 21;29(5):766-82. Epub 2016 Jun 21.

Institut de Neurosciences des Systèmes - Inserm UMR1106, Aix-Marseille Université Faculté de Médecine, 27, Boulevard Jean Moulin, 13005, Marseille, France.

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September 2016

Supratentorial clear cell ependymomas with branching capillaries demonstrate characteristic clinicopathological features and pathological activation of nuclear factor-kappaB signaling.

Neuro Oncol 2016 07 15;18(7):919-27. Epub 2016 Mar 15.

Department of Pathology and Neuropathology, Assistance Publique des Hôpitaux de Marseille (APHM), CHU Timone, Marseille, France (D.F.-B, E.T., A.M.d.P, C.B.); Aix-Marseille Université, Inserm, Marseille, France (D.F.-B, E.T., C.B., C.C.); Department of Pathology, CHU Caen, Hôpital de la Côte de Nacre, Caen, France (E.L.-Z); Department of Neurooncology, APHM, Marseille, France (E.T.); Department of Neuropathology, University of Bonn, Medical Center Sigmund-Freud, Bonn, Germany (S.J., T.P.); Department of Pathology and Neuropathology, Hospices civils de Lyon, Bron, France (A.J.); Department of Pathology, CHU de Saint-Etienne, Saint-Etienne, France (F.F.); Department of Neuropathology, CHU Sainte Anne, Paris, France (F.A.); Department of Pathology, CHU de Brest, Hôpital de la Cavale Blanche, Brest, France (I.Q.-R); Department of Pathology, CHU de Tours, Hôpital Trousseau, Tours, France (M.-C.M.); Department of Pathology, CHR d'Orléans, Hôpital de la Source, Orléans, France (A.H.); Department of Pathology, CHU de Poitiers, Hôpital la Milétrie, Poitiers, France (S.M.); Department of Pathology, CHU d'Amiens, Amiens, France (H.S.); Department of Pathology, CHU de Clermont-Ferrand, Clermont-Ferrand, France (C.G.); Department of Pathology, CHU de Limoges, Limoges, France (F.L.); Department of Neurosurgery, APHM, CHU Timone, Marseille, France (P.M.); Department of Pediatric Neurosurgery, APHM, CHU Timone, Marseille, France (D.S.).

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July 2016

Diffusion Tensor Imaging in Patients with Glioblastoma Multiforme Using the Supertoroidal Model.

PLoS One 2016 13;11(1):e0146693. Epub 2016 Jan 13.

Department of Computer Science, Institute of Mathematics and Statistics, University of São Paulo, São Paulo, Brazil.

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July 2016

Differential Diagnosis of Meningeal SFT-HPC and Meningioma: Which Immunohistochemical Markers Should Be Used?

Am J Surg Pathol 2016 Feb;40(2):270-8

*Department of Pathology and Neuropathology, Timone Hospital†INSERM, CRO2 UMR_S 911, Aix-Marseille Université (AMU)¶Department of Research and Innovation, Support Unit for Clinical Research and Economic Evaluation, Timone Hospital#EA 3279 Research Unit, Aix-Marseille Université (AMU), Marseille‡Department of Neuropathology, Pitié-Salpêtrière Hospital, Paris§Department of Neuropathology, CHU Lyon∥Department of Pathology, Wertheimer Hospital, Lyon, France.

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February 2016

Long-term results of carmustine wafer implantation for newly diagnosed glioblastomas: a controlled propensity-matched analysis of a French multicenter cohort.

Neuro Oncol 2015 Dec 16;17(12):1609-19. Epub 2015 Jul 16.

Department of Neurosurgery, Sainte-Anne Hospital, Paris, France (J.P., V.P., E.D., E.P., M.Z., B.D.); Paris Descartes University, Paris, France (J.P., V.P., E.D., E.P., M.Z., B.D.); Department of Histopathology and Animal Models, Institut Pasteur, Paris, France (J.P.); Réseau d'Etude des Gliomes (REG), France (J.P., L.B.); Public Health Department, Henri Mondor Teaching Hospital, Créteil, France (E.A.); Laboratoire d'Investigation Clinique, Université Paris Est Créteil, Créteil, France (E.A.); Radiotherapy Department, Centre de Lutte Contre le Cancer Paul Strauss, Strasbourg, France (G.N.); Radiobiology Laboratory, Federation of Translationnal Medicine de Strasbourg (FMTS), Strasbourg University, Strasbourg, France (G.N.); Department of Neurosurgery, Leeds General Infirmary, Leeds, United Kingdom (R.C.); Department of Pathology, Caen University Hospital, Caen, France (E.L.-Z.); CNRS, UMR 6232 CERVOxy Group, Caen, France (E.L.-Z.); University of Caen Basse-Normandie, UMR 6232 CERVOxy Group, Caen, France (E.L.-Z.); CEA, UMR 6232 CERVOxy Group, Caen, France (E.L.-Z.); Department of Neurosurgery, Maison Blanche Hospital, Reims University Hospital, Reims, France (J.D., C.-F.L.); Service of Neurosurgery D, Lyon Civil Hospitals, Pierre Wertheimer Neurological and Neurosurgical Hospital, Lyon, France (J.G.); Department of Neurosurgery, Faculty of Medicine, University Medical Center, University of Brest, Brest, France (P.D.H.); Department of Neurosurgery, University Hospital Pontchaillou, Rennes, France (P.-J.L.R.); Department of Neurosurgery, APHP Beaujon Hospital, Clichy, France (T.F.); Department of Neurosurgery, Sainte Anne Military Teaching Hospital, Toulon, France (N.D.); Department of Neurosurgery, University Hospital Jean Minjoz, Besançon, France (A.P.); Departement of Neurosurgery, University Hospital of Caen, University of Lower Normandy, Caen, France (E.E.); Department of Neurosurgery, Pasteur Hospital, Colmar, France (J.V.); Department of Neurosurgery, Haut

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December 2015

Neurosurgical and radiosurgical decision making in brain metastasis patients in the area of targeted therapies?

Chin Clin Oncol 2015 Jun;4(2):19

Department of Radiotherapy, Gustave Roussy University Hospital, Villejuif 94800, France.

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June 2015

Clinical course and progression-free survival of adult intracranial and spinal ependymoma patients.

Neuro Oncol 2015 Mar 13;17(3):440-7. Epub 2014 Aug 13.

Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (E.V.-B., M.R.G.); Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas (K.A., K.W.); Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas (Y.Y., J.W.); Office of Multicenter Clinical Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas (M.J.N.-R.); Department of Neurosurgery, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah (H.C.); Division of Hematology-Oncology, Children's Hospital Los Angeles, Los Angeles, California (G.D.); Departments of Neurology and Medicine (Medical Oncology), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (F.S.L.); Department of Neurosurgery, Assistance Publique-Hopitaux de Marseille, Aix-Marseille University, Marseille, France (P.M.); Departments of Neurology & Neurosurgery, Henry Ford Hospital, Detroit, Michigan (T.M.); Department of Neurology, Memorial-Sloan Kettering Cancer Center, New York, New York (A.O.); Department of Neurology, Stanford University & Lucile Packard Children's Hospital, Palo Alto, California (S.P.); Department of Neuro-Oncology, UCSF Helen Diller Comprehensive Cancer Center, San Francisco, California (M.P.); Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (H.I.R.); Department of Neuroscience, University San Giovanni Battista Hospital, Turin, Italy (R.S.); Department of Neurosurgery, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina (J.W.); Department of Family Health, School of Nursing, The University of Texas Health Science Center-Houston, Houston, Texas (T.S.A.); CERN Foundation, Dayton, Ohio.

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March 2015

18F-DOPA, a clinically available PET tracer to study brain inflammation?

Clin Nucl Med 2014 Apr;39(4):e283-5

From the *APHM, Hôpital de la Timone, Service Central de Biophysique et Médecine Nucléaire, Marseille; †Aix-Marseille Univ, CERIMED, Marseille; ‡APHM, Hôpital de la Timone, Service de Neurochirurgie, Marseille; §APHM, Hôpital de la Timone, Service de Neurologie, Marseille; ¶APHM, Hôpital de la Timone, Service d'Anatomie Pathologique et Neuropathologie, Marseille; and ∥Aix-Marseille Univ, CNRS, UMR7289, INT, Marseille, France.

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April 2014

Meningeal Rosai-Dorfman disease mimicking meningioma.

Ann Hematol 2014 Jun 24;93(6):937-40. Epub 2013 Dec 24.

Department of Pathology and Neuropathology, Timone Hospital, 264 rue Saint Pierre, 18285 CEDEX 5, Marseille, France.

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June 2014

Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening.

Exp Cell Res 2014 Feb 16;321(2):99-108. Epub 2013 Dec 16.

Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille, France; CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex, France; INSERM, U911, 13005 Marseille, France; Timone Hospital, 264 Rue Saint Pierre, 13385 Marseille Cedex 5, France; APHM, Timone Hospital, Department of Pathology, 13005 Marseille, France.

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February 2014

Association of matrix metalloproteinase 2 plasma level with response and survival in patients treated with bevacizumab for recurrent high-grade glioma.

Neuro Oncol 2014 Mar 9;16(3):392-9. Epub 2013 Dec 9.

Aix-Marseille Université, INSERM CRO2, Marseille, France (E.T., F.B., D.F.-B., L.O., O.C.); Assistance Publique-Hôpitaux de Marseille (AP-HM), CHU Timone, Service de Neuro-Oncologie, Marseille, France (E.T., M.B., M.M., C.B.); Aix-Marseille Université, Public Health Research Unit-EA3279 AP-HM, Marseille, France (A.L.); Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Avicenne, Service de Neurologie, Bobigny, France (A.C.); Université Paris Descartes, Laboratoire de Recherches Biochirurgicales, Hôpital Européen Georges Pompidou, Paris, France (A.C.); INSERM U 975, CNRS UMR 7225, Université Pierre et Marie Curie-Paris 6, Centre de Recherche de l'Institut du Cerveau et de la Moëlle Épinière UMR-S975, Paris, France (M.S.); AP-HP, Service Neurologie 2, Groupe Hospitalier Pitié-Salpêtrière, Paris, France (M.S.); AP-HM, CHU Timone, Service de Neurochirurgie, Marseille, France (P.M.); AP-HM, CHU Timone, Service d'Anatomopathologie, Marseille, France (D.F.-B.); CHU Nord, Laboratoire de Transfert, Marseille (L.O.).

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March 2014

Patients with brain metastases from colorectal cancer are not condemned.

Anticancer Res 2013 Dec;33(12):5645-8

Department of Digestive and Oncological Surgery, Timone Hospital, Aix-Marseille University, Marseille, France

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December 2013

Assessment of prognostic scores in brain metastases from breast cancer.

Neuro Oncol 2014 Mar 4;16(3):421-8. Epub 2013 Dec 4.

APHM, Timone Hospital, Departement of Neuro-Oncology, Marseille, France (E.T.); L'institut Paoli-Calmettes, Department of Medical Oncology, Marseille, France (E.T., A.G.); APHM, Timone Hospital, Department of Neurosurgery, Marseille, France (P.M.); L'institut Paoli-Calmettes, Department of Biostatistics, Marseille, France (B.E.); UMR911, CRO2, Aix-Marseille Université, Marseille, France (P.M.); L'institut Paoli-Calmettes, Department of Anatomic Pathology, Marseille, France (E.C.-J.); L'institut Paoli-Calmettes, Department of Radiotherapy, Marseille, France (A.T.).

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March 2014

Gene expression profiling of solitary fibrous tumors.

PLoS One 2013 29;8(5):e64497. Epub 2013 May 29.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes (IPC), UMR1068 Inserm, Marseille, France.

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January 2014

[Management of brain metastases for lung cancer patients].

Bull Cancer 2013 Mar;100(3):303-8

Aix-Marseille université, Assistance publique-Hôpitaux de Marseille, service d'oncologie multidisciplinaire et innovations thérapeutiques, Hôpital Nord, chemin des Bourrelly, 13915 Marseille Cedex 20, France.

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March 2013

[Stereotactic radiosurgery and radiotherapy for brain metastases].

Bull Cancer 2013 Jan;100(1):75-81

Centre hospitalier Lyon-Sud, département de radiothérapie oncologie, Pierre-Bénite, France.

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January 2013

[Place of surgery in brain metastases].

Bull Cancer 2013 Jan;100(1):51-6

AP-HM, CHU Timone, Aix-Marseille Université, département de neurochirurgie, Marseille, France.

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January 2013

[Cognition and radiation therapy for brain metastases: a new paradigm to define].

Bull Cancer 2013 Jan;100(1):69-74

Institut Paoli-Calmettes, département d'oncologie-radiothérapie, 232, boulevard Sainte-Marguerite, 13273 Marseille cedex 09, France.

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January 2013

Recent trends in epidemiology of brain metastases: an overview.

Anticancer Res 2012 Nov;32(11):4655-62

AP-HM, Timone Hospital, Departement of Neuro-oncology and Neuro-surgery, Marseille, France.

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November 2012

Molecular genetics of adult grade II gliomas: towards a comprehensive tumor classification system.

J Neurooncol 2012 Nov 14;110(2):205-13. Epub 2012 Aug 14.

Service d'Anatomie Pathologique et de Neuropathologie, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, 13000, Marseille, France.

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November 2012

FDG-PET predicts survival in recurrent high-grade gliomas treated with bevacizumab and irinotecan.

Neuro Oncol 2012 May 29;14(5):649-57. Epub 2012 Feb 29.

Service Central de Biophysique et Médecine Nucléaire, Assistance Publique des Hôpitaux de Marseille, CHU Timone,Aix-Marseille University, Marseille, France.

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May 2012

Magnetic resonance metabolic imaging of glioma.

Sci Transl Med 2012 Jan;4(116):116ps1

Department of Neurosurgery, Hôpital de la Timone, APHM, 13005 Marseille, France.

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January 2012

Independent prognostic value of pre-treatment 18-FDG-PET in high-grade gliomas.

J Neurooncol 2012 May 15;107(3):527-35. Epub 2011 Dec 15.

APHM, Hôpital de la Timone, Service Central de Biophysique et Médecine Nucléaire, 13005 Marseille, France.

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May 2012

Cognitive impairment in patients with Pseudotumor Cerebri Syndrome.

Behav Neurol 2011 ;24(2):143-8

Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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September 2011

Systems for long-segment percutaneous spinal fixation: technical feasibility for various indications.

Acta Neurochir (Wien) 2011 May 3;153(5):985-91. Epub 2011 Mar 3.

Université de la Méditerranée, Service d'orthopédie, CHU Nord, Marseille, France.

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May 2011

Multidisciplinary management of giant functional petrous bone paraganglioma.

Acta Neurochir (Wien) 2011 Jan 8;153(1):85-9; discussion 89. Epub 2010 Oct 8.

Department of Neurosurgery, Hôpital La Timone, 264 rue Saint Pierre 13385 Marseille cedex 05, Marseille, France.

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January 2011

Absence of R140Q mutation of isocitrate dehydrogenase 2 in gliomas and breast cancers.

Oncol Lett 2010 Sep 1;1(5):883-884. Epub 2010 Sep 1.

Centre de Recherche en Cancérologie de Marseille, Laboratoire d' Oncologie Moléculaire, UMR891 Inserm, Institut Paoli-Calmettes, 13009 Marseille.

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September 2010

Percutaneous kyphoplasty and pedicle screw fixation for the management of thoraco-lumbar burst fractures.

Eur Spine J 2010 Aug 22;19(8):1281-7. Epub 2010 May 22.

Service de neurochirurgie Pr Dufour, Hôpital de la Timone, Université de la Mediterranée, 249 rue Saint Pierre, 13005 Marseille, France.

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August 2010

Epidermal growth factor receptor in glioblastomas: correlation between gene copy number and protein expression.

Hum Pathol 2010 Jun 29;41(6):815-23. Epub 2010 Mar 29.

Département d'Anatomie Pathologie et de Neuropathologie, Centre Hospitalier Universitaire (CHU) Timone, 13005 Marseille, France.

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June 2010

Cervicosternotomy as an anterior approach to the upper thoracic and cervicothoracic spinal junction.

J Neurosurg Spine 2010 Feb;12(2):160-4

Department of Neurosurgery, Centre Hospitalier Régional Universitaire, Timone, Marseille, France.

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February 2010

High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas.

Acta Neuropathol 2009 Dec 23;118(6):745-54. Epub 2009 Sep 23.

INSERM U911, Centre de Recherche en Oncologie et Oncopharmacologie (CRO2), Angiogenèse, Invasivité et Microenvironnement Tumoral, Faculté de Médecine Timone, 27, Bd Jean Moulin, 13005, Marseille, France.

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December 2009

Open kyphoplasty for management of severe osteoporotic spinal fractures.

Neurosurgery 2009 May;64(5 Suppl 2):350-4; discussion 354-5

Department of Neurosurgery, Timone Hospital, Marseille, France. sfuentes@ ap- hm.fr

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May 2009

[The brain, review of anatomic and functional correlations].

Soins 2009 Mar(733):26-7

Service de Neurochirurgie, Hôpital de La Timone, Marseille.

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March 2009

A2B5 cells from human glioblastoma have cancer stem cell properties.

Brain Pathol 2010 Jan 20;20(1):211-21. Epub 2009 Feb 20.

Université de la Méditerranée Aix-Marseille II, Faculté de Médecine la Timone, INSERM UMR911-CRO2, Angiogenèse, Invasivité et Microenvironnement Tumoral, Marseille cedex 05, France.

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January 2010

Functional cerebral venous outflow in swine and baboon: feasibility of an intracranial venous hypertension model.

J Invest Surg 2008 Nov-Dec;21(6):323-9

L2PTV-Laboratoire de Physiopathologie et de Therapeutique Vasculaire, Faculté de médecine AIX-Marseille, Marseille, France.

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March 2009

FDG-PET to predict different patterns of progression in multicentric glioblastoma: a case report.

J Neurooncol 2008 Oct 21;90(1):47-51. Epub 2008 Jun 21.

Department of Nuclear Medicine, Centre Hospitalo-Universitaire de la Timone (CHU Timone), 264 Rue Saint-Pierre, 13385, Marseille Cedex 5, France.

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October 2008

Linezolid for treatment of subdural empyema due to Streptococcus: case reports.

Surg Neurol 2009 Jan 11;71(1):89-91; discussion 91. Epub 2008 Feb 11.

Department of Anesthesiology and Intensive Care, CHU Timone, Université de la Méditerranée, Marseille, France.

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January 2009

Correlations between MR and endothelial hyperplasia in low-grade gliomas.

J Magn Reson Imaging 2007 Jul;26(1):52-60

Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR CNRS 6612, Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France.

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July 2007

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.

J Clin Oncol 2007 Apr;25(12):1470-5

Unité de Neuro-Oncologie, Service de Neurochirurgie, Centre Hospitalier Universitaire Timone, Assistance Publique-Hôpitaux de Marseille, and Université de la Méditérranée, Faculté de Médecine de Marseille, Marseille, France.

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April 2007

Spinal epidural abscess.

N Engl J Med 2007 Feb;356(6):638; author reply 638-9

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February 2007

Prospective controlled trial of gamma knife surgery for essential trigeminal neuralgia.

J Neurosurg 2006 Jun;104(6):913-24

Departments of Functional Neurosurgery and Neurology, Timone University Hospital, Marseille, France.

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June 2006

Brainstem metastases: management using gamma knife radiosurgery.

Neurosurgery 2006 Jan;58(1):37-42; discussion 37-42

Neurosurgical Service, Timone University Hospital Center, Marseille, France.

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January 2006