Philippe Major

Philippe Major

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Philippe Major

Philippe Major

Publications by authors named "Philippe Major"

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37Publications

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Sub-cortical brain morphometry and its relationship with cognition in rolandic epilepsy.

Epilepsy Res 2017 12 7;138:39-45. Epub 2017 Oct 7.

CHU Sainte-Justine, Montreal, Quebec, Canada; University of Montreal, Department of Psychology, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.eplepsyres.2017.09.007DOI Listing
December 2017

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.

Authors:
Fadi F Hamdan Candace T Myers Patrick Cossette Philippe Lemay Dan Spiegelman Alexandre Dionne Laporte Christina Nassif Ousmane Diallo Jean Monlong Maxime Cadieux-Dion Sylvia Dobrzeniecka Caroline Meloche Kyle Retterer Megan T Cho Jill A Rosenfeld Weimin Bi Christine Massicotte Marguerite Miguet Ledia Brunga Brigid M Regan Kelly Mo Cory Tam Amy Schneider Georgie Hollingsworth David R FitzPatrick Alan Donaldson Natalie Canham Edward Blair Bronwyn Kerr Andrew E Fry Rhys H Thomas Joss Shelagh Jane A Hurst Helen Brittain Moira Blyth Robert Roger Lebel Erica H Gerkes Laura Davis-Keppen Quinn Stein Wendy K Chung Sara J Dorison Paul J Benke Emily Fassi Nicole Corsten-Janssen Erik-Jan Kamsteeg Frederic T Mau-Them Ange-Line Bruel Alain Verloes Katrin Õunap Monica H Wojcik Dara V F Albert Sunita Venkateswaran Tyson Ware Dean Jones Yu-Chi Liu Shekeeb S Mohammad Peyman Bizargity Carlos A Bacino Vincenzo Leuzzi Simone Martinelli Bruno Dallapiccola Marco Tartaglia Lubov Blumkin Klaas J Wierenga Gabriela Purcarin James J O'Byrne Sylvia Stockler Anna Lehman Boris Keren Marie-Christine Nougues Cyril Mignot Stéphane Auvin Caroline Nava Susan M Hiatt Martina Bebin Yunru Shao Fernando Scaglia Seema R Lalani Richard E Frye Imad T Jarjour Stéphanie Jacques Renee-Myriam Boucher Emilie Riou Myriam Srour Lionel Carmant Anne Lortie Philippe Major Paola Diadori François Dubeau Guy D'Anjou Guillaume Bourque Samuel F Berkovic Lynette G Sadleir Philippe M Campeau Zoha Kibar Ronald G Lafrenière Simon L Girard Saadet Mercimek-Mahmutoglu Cyrus Boelman Guy A Rouleau Ingrid E Scheffer Heather C Mefford Danielle M Andrade Elsa Rossignol Berge A Minassian Jacques L Michaud

Am J Hum Genet 2017 Nov;101(5):664-685

Centre Hospitalier Universitaire Sainte-Justine Research Center, Montreal, QC H3T1C5, Canada; Department of Neurosciences, Université de Montréal, Montreal, QC H3T1J4, Canada; Department of Pediatrics, Université de Montréal, Montreal, QC H3T1C5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673604PMC
November 2017

encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects.

J Med Genet 2017 07 4;54(7):460-470. Epub 2017 Apr 4.

Institute of Human Genetics, University of Leipzig Hospitals and Clinics, Leipzig, Germany.

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http://dx.doi.org/10.1136/jmedgenet-2016-104509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656050PMC
July 2017

Altered visual repetition suppression in Fragile X Syndrome: New evidence from ERPs and oscillatory activity.

Int J Dev Neurosci 2017 Jun 19;59:52-59. Epub 2017 Mar 19.

Departement de Psychologie, Université de Montréal, Montreal, Canada; Neuroscience of Early Development (NED), Montreal, Canada; Centre de Recherche en Neuropsychologie et Cognition (CERNEC), Montreal, Canada; Research Center of the CHU Ste-Justine Mother and Child University Hospital Center, Université de Montreal, Quebec, Canada; International Laboratory for Brain, Music and Sound Research (BRAMS), Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ijdevneu.2017.03.008DOI Listing
June 2017

Periictal activity in cooled asphyxiated neonates with seizures.

Seizure 2017 Apr 2;47:13-16. Epub 2017 Mar 2.

Division of Neurology, CHU Sainte Justine, Department of Neurosciences and Paediatrics, University of Montreal, Montreal, Canada; CHU Sainte-Justine Research Center, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2017.03.002DOI Listing
April 2017

Accelerated Cardiac Rhabdomyoma Regression with Everolimus in Infants with Tuberous Sclerosis Complex.

Pediatr Cardiol 2017 Feb 23;38(2):394-400. Epub 2016 Nov 23.

Division of Pediatric Cardiology, Department of Pediatrics, CHU Sainte-Justine, University of Montreal, 3175, Côte Sainte-Catherine, Montréal, QC, H3T 1C5, Canada.

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http://dx.doi.org/10.1007/s00246-016-1528-yDOI Listing
February 2017

Predictive Factors for Epilepsy in Pediatric Patients With Sturge-Weber Syndrome.

Pediatr Neurol 2016 11 18;64:52-58. Epub 2016 Aug 18.

Division of Neurology, Department of Neurosciences and Pediatrics, CHU Sainte Justine, University of Montreal, Montreal, Canada.

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http://dx.doi.org/10.1016/j.pediatrneurol.2016.08.009DOI Listing
November 2016

Electrophysiological Evidences of Visual Field Alterations in Children Exposed to Vigabatrin Early in Life.

Pediatr Neurol 2016 06 17;59:47-53. Epub 2016 Mar 17.

Research Center, CHU Sainte-Justine, Montreal, Quebec, Canada; Department of Ophtalmology, Université de Montréal, Montreal, Quebec, Canada; Department of Psychology, Université du Québec à Montréal, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2016.03.001DOI Listing
June 2016

Efficacy and safety of lacosamide as an adjunctive therapy for refractory focal epilepsy in paediatric patients: a retrospective single-centre study.

Epileptic Disord 2015 Dec;17(4):436-43

CHU Sainte-Justine Research Center, Division of Neurology, Department of Neurosciences and Paediatrics, CHU Sainte Justine, University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1684/epd.2015.0782DOI Listing
December 2015

Resective Epilepsy Surgery for Tuberous Sclerosis in Children: Determining Predictors of Seizure Outcomes in a Multicenter Retrospective Cohort Study.

Neurosurgery 2015 Oct;77(4):517-24; discussion 524

*Department of Neurosurgery, Miami Children's Hospital, Miami, Florida; ‡Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada; §Department of Neurosurgery, New York University Langone Medical Center, New York, New York; ¶Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio; ‖Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; #Division of Neurology, BC Children's Hospital, Vancouver, BC, Canada; **Division of Neurology, CHU Sainte-Justine, Montreal, QC, Canada; ‡‡Department of Neurosurgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania; §§Department of Neurology, New York University Langone Medical Center, New York, New York; ¶¶Department of Neurology, Cleveland Clinic Foundation, Cleveland, Ohio; ‖‖Division of Neurosurgery, BC Children's Hospital, Vancouver, BC, Canada; ##Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada; ***Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada.

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http://pdfs.journals.lww.com/neurosurgery/2015/10000/Resecti
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1227/NEU.0000000000000875DOI Listing
October 2015

Lymphangioleiomyomatosis and Tuberous Sclerosis Complex in Quebec: Prevalence and Health-care Utilization.

Chest 2015 Aug;148(2):444-449

Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre.

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http://dx.doi.org/10.1378/chest.14-3095DOI Listing
August 2015

Use of mTOR inhibitor everolimus in three neonates for treatment of tumors associated with tuberous sclerosis complex.

Pediatr Neurol 2015 Apr 14;52(4):450-3. Epub 2015 Jan 14.

Department of Neurosciences, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2015.01.004DOI Listing
April 2015

Neuropsychological functioning in children with temporal lobe epilepsy and hippocampal atrophy without mesial temporal sclerosis: a distinct clinical entity?

Epilepsy Behav 2015 Mar 16;44:17-22. Epub 2015 Jan 16.

Centre de Recherche du CHU Sainte-Justine, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, QC H3T 1C5, Canada; Centre de Recherche en Neuropsychologie et Cognition (CERNEC), Département de Psychologie, Université de Montréal, 90 Avenue Vincent-d'Indy, Montréal, QC H2V 2S9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2014.12.023DOI Listing
March 2015

The genetic landscape of infantile spasms.

Hum Mol Genet 2014 Sep 29;23(18):4846-58. Epub 2014 Apr 29.

Department of Pediatrics and Department of Neurosciences, Université de Montréal, Montréal, QC, Canada, CHU Ste-Justine Research Center, Montréal, QC, Canada,

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddu199DOI Listing
September 2014

Alterations of visual and auditory evoked potentials in fragile X syndrome.

Int J Dev Neurosci 2014 Aug 27;36:90-7. Epub 2014 May 27.

Research Center of the CHU Ste-Justine Mother and Child University Hospital Center, University of Montreal, Quebec, Canada; Psychology Department, University of Montreal, Quebec, Canada; Centre de Recherche en Neuropsychologie et Cognition, University of Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ijdevneu.2014.05.003DOI Listing
August 2014

Persistent migraine aura in an adolescent girl.

J AAPOS 2013 Aug 16;17(4):426-7. Epub 2013 Jul 16.

Department of Pediatric Ophthalmology, Sainte-Justine's Hospital, University of Montreal, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.jaapos.2013.03.016DOI Listing
August 2013

The clinical spectrum of nodular heterotopias in children: report of 31 patients.

Epilepsia 2011 Apr 14;52(4):728-37. Epub 2011 Feb 14.

Centre de recherche du CHUM, Montréal, Université de Montréal, Quebec, Canada.

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http://dx.doi.org/10.1111/j.1528-1167.2010.02975.xDOI Listing
April 2011

The combination of subdural and depth electrodes for intracranial EEG investigation of suspected insular (perisylvian) epilepsy.

Epilepsia 2011 Mar 4;52(3):458-66. Epub 2011 Jan 4.

Service de Neurochirurgie, Hôpital Notre-Dame du CHUM, Université de Montréal, Quebec, Canada.

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http://dx.doi.org/10.1111/j.1528-1167.2010.02910.xDOI Listing
March 2011

Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex.

Authors:
Philippe Major

Aging (Albany NY) 2011 Mar;3(3):189-91

Department of Pediatrics, Neurology Service, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Québec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091516PMC
http://dx.doi.org/10.18632/aging.100298DOI Listing
March 2011

Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex.

J Neurosurg Pediatr 2010 Oct;6(4):381-4

Department of Pediatrics, Neurology Service, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Québec, Canada.

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http://dx.doi.org/10.3171/2010.7.PEDS10221DOI Listing
October 2010

The natural history of epilepsy in tuberous sclerosis complex.

Epilepsia 2010 Jul 22;51(7):1236-41. Epub 2009 Dec 22.

Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://doi.wiley.com/10.1111/j.1528-1167.2009.02474.x
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http://dx.doi.org/10.1111/j.1528-1167.2009.02474.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065368PMC
July 2010

Associations between electroencephalographic and magnetic resonance imaging findings in tuberous sclerosis complex.

Epilepsy Res 2009 Dec 26;87(2-3):197-202. Epub 2009 Sep 26.

Carol and James Herscot Center for Tuberous Sclerosis Complex, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.eplepsyres.2009.09.001DOI Listing
December 2009

Cyst-like tubers are associated with TSC2 and epilepsy in tuberous sclerosis complex.

Neurology 2009 Mar;72(13):1165-9

Carol and James Herscot Center for Tuberous Sclerosis Complex, 175 Cambridge Street, Suite 340, Boston, MA 02114, USA.

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http://www.neurology.org/content/72/13/1165.full.pdf
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http://www.neurology.org/cgi/doi/10.1212/01.wnl.0000345365.9
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http://dx.doi.org/10.1212/01.wnl.0000345365.92821.86DOI Listing
March 2009

Periinsular hemispherotomy in children with stroke-induced refractory epilepsy.

J Neurosurg Pediatr 2009 Feb;3(2):115-20

Department of Pediatric Neurosurgery, Hôpital des Enfants La Timone, Marseille, France.

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http://dx.doi.org/10.3171/2008.11.PEDS08218DOI Listing
February 2009

Are cortical tubers epileptogenic? Evidence from electrocorticography.

Epilepsia 2009 Jan;50(1):147-54

Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/j.1528-1167.2008.01814.xDOI Listing
January 2009

Pyridoxine supplementation for the treatment of levetiracetam-induced behavior side effects in children: preliminary results.

Epilepsy Behav 2008 Oct 3;13(3):557-9. Epub 2008 Aug 3.

Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152550500800210
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http://dx.doi.org/10.1016/j.yebeh.2008.07.004DOI Listing
October 2008

Vagus nerve stimulation for intractable epilepsy in tuberous sclerosis complex.

Epilepsy Behav 2008 Aug 8;13(2):357-60. Epub 2008 May 8.

Department of Neurology and Pediatrics, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.yebeh.2008.04.001DOI Listing
August 2008

Vigabatrin in the treatment of childhood epilepsy: a retrospective chart review of efficacy and safety profile.

Epilepsia 2008 Jul;49(7):1186-91

Pediatric Epilepsy Service, Neurology Department, Massachusettes General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1111/j.1528-1167.2008.01589.xDOI Listing
July 2008

Seizures in children: laboratory diagnosis and management.

Pediatr Rev 2007 Nov;28(11):405-14

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1542/pir.28-11-405DOI Listing
November 2007

Seizures in children: determining the variation.

Pediatr Rev 2007 Oct;28(10):363-71

Department of Neurology, Massachusetts General Hospital, Boston, Mass, USA.

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http://pedsinreview.aappublications.org/lookup/doi/10.1542/p
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http://dx.doi.org/10.1542/pir.28-10-363DOI Listing
October 2007