Publications by authors named "Philippe Lesnik"

49Publications

Distinct Postprandial Bile Acids Responses to a High-Calorie Diet in Men Volunteers Underscore Metabolically Healthy and Unhealthy Phenotypes.

Authors:

Antonin Lamaziere Dominique Rainteau Pukar Kc Lydie Humbert Emilie Gauliard Farid Ichou Maharajah Ponnaiah Nadine Bouby Joe-Elie Salem Jean-Maurice Mallet Maryse Guerin Philippe Lesnik

Nutrients 2020 Nov 19;12(11). Epub 2020 Nov 19.

Institut National de la Santé et de la Recherche Médicale (INSERM, UMR_S 1166-ICAN), Research Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine-Hôpital Pitié-Salpêtrière, Sorbonne Université, F-75013 Paris, France.

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November 2020

Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels.

Authors:

Qianqian Zhang Zexi Cai Marie Lhomme Goutam Sahana Philippe Lesnik Maryse Guerin Merete Fredholm Peter Karlskov-Mortensen

Sci Rep 2020 10 28;10(1):18434. Epub 2020 Oct 28.

Animal Genetics, Bioinformatics and Breeding, Department of Veterinary and Animal Sciences, University of Copenhagen, Gronnegaardsvej 3, 1870, Frederikgsberg C, Denmark.

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October 2020

Gut Microbiome and Space Travelers' Health: State of the Art and Possible Pro/Prebiotic Strategies for Long-Term Space Missions.

Authors:

Silvia Turroni Marciane Magnani Pukar Kc Philippe Lesnik Hubert Vidal Martina Heer

Front Physiol 2020 8;11:553929. Epub 2020 Sep 8.

International University of Applied Sciences, Bad Reichenhall, Germany.

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September 2020

Interleukin-1β and Risk of Premature Death in Patients With Myocardial Infarction.

Authors:

Johanne Silvain Mathieu Kerneis Michel Zeitouni Benoit Lattuca Sophie Galier Delphine Brugier Emilie Mertens Niki Procopi Gaspard Suc Tomy Salloum Eric Frisdal Wilfried Le Goff Jean-Philippe Collet Eric Vicaut Philippe Lesnik Gilles Montalescot Maryse Guerin

J Am Coll Cardiol 2020 Oct 27;76(15):1763-1773. Epub 2020 Aug 27.

INSERM UMRS1166 Hôpital de la Pitié, Paris, France, Sorbonne Université, Paris, France, ICAN - Institute of CardioMetabolism and Nutrition, Hôpital de la Pitié, Paris, France.

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October 2020

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.

Authors:

Amine Toubal Badr Kiaf Lucie Beaudoin Lucie Cagninacci Moez Rhimi Blandine Fruchet Jennifer da Silva Alexandra J Corbett Yannick Simoni Olivier Lantz Jamie Rossjohn James McCluskey Philippe Lesnik Emmanuelle Maguin Agnès Lehuen

Nat Commun 2020 07 24;11(1):3755. Epub 2020 Jul 24.

Université de Paris, Institut Cochin INSERM, CNRS F-75014, Paris, France.

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July 2020

Exploring the Bacterial Impact on Cholesterol Cycle: A Numerical Study.

Authors:

Mélanie Bourgin Simon Labarthe Aicha Kriaa Marie Lhomme Philippe Gérard Philippe Lesnik Béatrice Laroche Emmanuelle Maguin Moez Rhimi

Front Microbiol 2020 10;11:1121. Epub 2020 Jun 10.

Micalis Institute, Université Paris-Saclay, INRAE, AgroParisTech, Jouy-en-Josas, France.

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June 2020

Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis.

Authors:

Sophie Tran Ines Baba Lucie Poupel Sébastien Dussaud Martine Moreau Adélaïde Gélineau Geneviève Marcelin Elissa Magréau-Davy Melissa Ouhachi Philippe Lesnik Alexandre Boissonnas Wilfried Le Goff Björn E Clausen Laurent Yvan-Charvet Florian Sennlaub Thierry Huby Emmanuel L Gautier

Immunity 2020 Sep 19;53(3):627-640.e5. Epub 2020 Jun 19.

Institut National de la Santé et de la Recherche Médicale (Inserm, UMR_S 1166), Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France. Electronic address:

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September 2020

Reduced Reverse Cholesterol Transport Efficacy in Healthy Men with Undesirable Postprandial Triglyceride Response.

Authors:

Alexandre Motte Motte Julie Gall Gall Joe-Elie Salem Eric Dasque Martine Lebot Eric Frisdal Sophie Galier Elise F Villard Elodie Bouaziz-Amar Jean-Marc Lacorte Beny Charbit Wilfried Le Goff Philippe Lesnik Maryse Guerin

Biomolecules 2020 05 25;10(5). Epub 2020 May 25.

Research Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.

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May 2020

Unraveling Host-Gut Microbiota Dialogue and Its Impact on Cholesterol Levels.

Authors:

Remy Villette Pukar Kc Sophie Beliard Maria Fernanda Salas Tapia Dominique Rainteau Maryse Guerin Philippe Lesnik

Front Pharmacol 2020 3;11:278. Epub 2020 Apr 3.

INSERM, UMRS U1166, "Integrative Biology of Atherosclerosis" and Sorbonne Université, Paris, France.

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April 2020

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis.

Authors:

Lynda Aoudjehane Jérémie Gautheron Wilfried Le Goff Claire Goumard Julia Gilaizeau Chan Sonavine Nget Eric Savier Muhammad Atif Philippe Lesnik Romain Morichon Yves Chrétien Yvon Calmus Olivier Scatton Chantal Housset Filomena Conti

Dis Model Mech 2020 04 29;13(4). Epub 2020 Apr 29.

Institute of Cardiometabolism and Nutrition (ICAN), Sorbonne Université, INSERM, Paris 75012, France.

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April 2020

Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism.

Authors:

Mette Juul Jacobsen Jakob H Havgaard Christian Anthon Caroline M Junker Mentzel Susanna Cirera Poula Maltha Krogh Sachin Pundhir Peter Karlskov-Mortensen Camilla S Bruun Philippe Lesnik Maryse Guerin Jan Gorodkin Claus B Jørgensen Merete Fredholm Romain Barrès

Front Genet 2019 17;10:1268. Epub 2019 Dec 17.

Novo Nordisk Foundation Centre for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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December 2019

Free cholesterol transfer to high-density lipoprotein (HDL) upon triglyceride lipolysis underlies the U-shape relationship between HDL-cholesterol and cardiovascular disease.

Eur J Prev Cardiol 2020 Oct 15;27(15):1606-1616. Epub 2019 Dec 15.

National Institute for Health and Medical Research (INSERM) UMR_S 1166, Faculty of Medicine Pitié-Salpétrière, Paris, France.

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October 2020

The intestinal microbiota regulates host cholesterol homeostasis.

Authors:

Tiphaine Le Roy Emelyne Lécuyer Benoit Chassaing Moez Rhimi Marie Lhomme Samira Boudebbouze Farid Ichou Júlia Haro Barceló Thierry Huby Maryse Guerin Philippe Giral Emmanuelle Maguin Nathalie Kapel Philippe Gérard Karine Clément Philippe Lesnik

BMC Biol 2019 11 27;17(1):94. Epub 2019 Nov 27.

INSERM, UMRS 1166, team "Integrative Biology of Atherosclerosis", Sorbonne Universités, Hôpital Pitié-Salpêtrière, Paris, France.

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November 2019

Antiatherogenic properties of high-density lipoproteins from arterial plasma are attenuated as compared to their counterparts of venous origin.

Authors:

Dominique Bonnefont-Rousselot Leila Benouda Randa Bittar Maryam Darabi-Amin Pierre Demondion Philippe Lesnik Pascal Leprince Anatol Kontush Jean-Christophe Charniot Philippe Giral

Nutr Metab Cardiovasc Dis 2020 01 3;30(1):33-39. Epub 2019 Aug 3.

National Institute for Health and Medical Research (INSERM), UMR ICAN 1166, Sorbonne University Paris 6, Pitié-Salpêtrière - Charles Foix Hospital, AP-HP, Paris, France; Department of Endocrinology and Metabolism, Pitié-Salpêtrière - Charles Foix Hospital, AP-HP, Paris, France. Electronic address:

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January 2020

Targeted invalidation of SR-B1 in macrophages reduces macrophage apoptosis and accelerates atherosclerosis.

Authors:

Lauriane Galle-Treger Martine Moreau Raphaëlle Ballaire Lucie Poupel Thomas Huby Emanuele Sasso Fulvia Troise Francesco Poti Philippe Lesnik Wilfried Le Goff Emmanuel L Gautier Thierry Huby

Cardiovasc Res 2020 03;116(3):554-565

Sorbonne Université, INSERM, UMR_S 1166 ICAN, F-75013, Paris, France.

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March 2020

Association of Serum Cholesterol Efflux Capacity With Mortality in Patients With ST-Segment Elevation Myocardial Infarction.

Authors:

Maryse Guerin Johanne Silvain Julie Gall Maryam Darabi Myriam Berthet Eric Frisdal Marie Hauguel-Moreau Michel Zeitouni Mathieu Kerneis Benoit Lattuca Delphine Brugier Jean-Philippe Collet Philippe Lesnik Gilles Montalescot

J Am Coll Cardiol 2018 12;72(25):3259-3269

INSERM UMRS1166, ICAN - Institute of CardioMetabolism and Nutrition, Hôpital Pitié-Salpêtrière, Sorbonne Université, Paris, France; Sorbonne Université, ACTION Study Group, INSERM UMRS1166, ICAN - Institute of CardioMetabolism and Nutrition, Institut de Cardiologie, Hôpital Pitié-Salpêtrière, Paris, France. Electronic address:

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December 2018

Cholesterol efflux capacity of large, small and total HDL particles is unaltered by atorvastatin in patients with type 2 diabetes.

Authors:

Liliana Muñoz-Hernandez Raul J Ortiz-Bautista Griselda Brito-Córdova Francisco Lozano-Arvizu Sharim Saucedo Oscar Pérez-Méndez Alejandro Zentella-Dehesa Carolane Dauteuille Marie Lhomme Philippe Lesnik M John Chapman Anatol Kontush Carlos A Aguilar Salinas

Atherosclerosis 2018 10 24;277:72-79. Epub 2018 Aug 24.

Unidad de Investigación de Enfermedades Metabólicas, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Avenue Vasco de Quiroga 15, Tlalpán, CP 14080, Mexico City, Mexico; Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador, Avenue Vasco de Quiroga 15, Tlalpán, CP 14080, Mexico City, Mexico; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Calle del puente 222, Ejidos de Huipulco, Tlalpán, 14380, Mexico City, Mexico. Electronic address:

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October 2018

Hypoalphalipoproteinemia and BRAF Mutation Are Major Predictors of Aortic Infiltration in the Erdheim-Chester Disease.

Authors:

Fleur Cohen-Aubart Maryse Guerin Lucie Poupel Philippe Cluzel Flora Saint-Charles Frédéric Charlotte Youssef Arsafi Jean-François Emile Eric Frisdal Carine Le Goff Jean Donadieu Zahir Amoura Philippe Lesnik Julien Haroche Wilfried Le Goff

Arterioscler Thromb Vasc Biol 2018 08;38(8):1913-1925

Inserm, Institute of Cardiometabolism and Nutrition (ICAN), UMR_S1166, Hôpital de la Pitié, Sorbonne Université, Paris, France (M.G., F.S.-C., Y.A., E.F., P.L., W.L.G.).

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August 2018

Small dense HDLs display potent vasorelaxing activity, reflecting their elevated content of sphingosine-1-phosphate.

Authors:

Laurence Perségol Maryam Darabi Carolane Dauteuille Marie Lhomme Sandrine Chantepie Kerry-Anne Rye Patrice Therond M John Chapman Robert Salvayre Anne Nègre-Salvayre Philippe Lesnik Serge Monier Anatol Kontush

J Lipid Res 2018 01 17;59(1):25-34. Epub 2017 Nov 17.

National Institute for Health and Medical Research (INSERM), UMR-S 1166 ICAN, University of Pierre and Marie Curie-Paris 6, and AP-HP, Groupe Hospitalier Pitié-Salpétrière, Paris, France

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January 2018

Haplotypes on pig chromosome 3 distinguish metabolically healthy from unhealthy obese individuals.

Authors:

Simona D Frederiksen Peter Karlskov-Mortensen Sameer D Pant Maryse Guerin Philippe Lesnik Claus B Jørgensen Susanna Cirera Camilla S Bruun Thomas Mark Merete Fredholm

PLoS One 2017 1;12(6):e0178828. Epub 2017 Jun 1.

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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September 2017