Philippe Conus

Philippe Conus

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Philippe Conus

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Early intervention for bipolar disorder - Do current treatment guidelines provide recommendations for the early stages of the disorder?

J Affect Disord 2019 Oct 30;257:669-677. Epub 2019 Jul 30.

Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, Australia; Orygen Youth Health, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.07.062DOI Listing
October 2019

Precision psychiatry: Promises made-Promises to be kept?

Aust N Z J Psychiatry 2019 Sep 17;53(9):841-843. Epub 2019 May 17.

1 Psychiatric Liaison Service, Lausanne University Hospital (CHUV), Lausanne University, Lausanne, Switzerland.

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http://dx.doi.org/10.1177/0004867419849482DOI Listing
September 2019

Amisulpride: Real-World Evidence of Dose Adaptation and Effect on Prolactin Concentrations and Body Weight Gain by Pharmacokinetic/Pharmacodynamic Analyses.

Clin Pharmacokinet 2019 Sep 25. Epub 2019 Sep 25.

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Hospital of Cery, Prilly, Switzerland.

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http://dx.doi.org/10.1007/s40262-019-00821-wDOI Listing
September 2019

Frontal cortical thickness correlates positively with impulsivity in early psychosis male patients.

Early Interv Psychiatry 2019 08 17;13(4):848-852. Epub 2018 May 17.

Department of Psychiatry, Service of General Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1111/eip.12678DOI Listing
August 2019

Urbanicity: The need for new avenues to explore the link between urban living and psychosis.

Early Interv Psychiatry 2019 Aug 6. Epub 2019 Aug 6.

Treatment and early Intervention in Psychosis Program, Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital CHUV, Lausanne, Switzerland.

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http://dx.doi.org/10.1111/eip.12861DOI Listing
August 2019

[Alternatives to psychiatric hospitalisation].

Rev Med Suisse 2019 Aug;15(658):1402-1406

Service de psychiatrie communautaire, CHUV, 1011 Lausanne.

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August 2019

Early changes of blood lipid levels during psychotropic drug treatment as predictors of long-term lipid changes and of new onset dyslipidemia.

J Clin Lipidol 2018 Jan - Feb;12(1):219-229. Epub 2017 Oct 16.

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2017.10.002DOI Listing
July 2019

Violent behaviour in early psychosis patients: Can we identify clinical risk profiles?

Early Interv Psychiatry 2019 06 15;13(3):517-524. Epub 2017 Nov 15.

Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1111/eip.12512DOI Listing
June 2019

City Avoidance in the Early Phase of Psychosis: A Neglected Domain of Assessment and a Potential Target for Recovery Strategies.

Front Psychiatry 2019 3;10:342. Epub 2019 Jun 3.

Treatment and Early Intervention in Psychosis Program (TIPP), Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Clinique de Cery, Prilly, Switzerland.

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http://dx.doi.org/10.3389/fpsyt.2019.00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557174PMC
June 2019

Migration in patients with early psychosis: A 3-year prospective follow-up study.

Psychiatry Res 2019 05 13;275:108-114. Epub 2019 Mar 13.

Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S01651781193050
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http://dx.doi.org/10.1016/j.psychres.2019.03.021DOI Listing
May 2019

Identifying patterns in psychiatric hospital stays with statistical methods: towards a typology of post-deinstitutionalization hospitalization trajectories.

Soc Psychiatry Psychiatr Epidemiol 2019 Apr 30. Epub 2019 Apr 30.

Service of Community Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/s00127-019-01717-7DOI Listing
April 2019

Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging.

Transl Psychiatry 2019 02 4;9(1):62. Epub 2019 Feb 4.

Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

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http://www.nature.com/articles/s41398-019-0392-y
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http://dx.doi.org/10.1038/s41398-019-0392-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362225PMC
February 2019

[Psychiatry : Swiss recommendations for treatment].

Rev Med Suisse 2019 Jan;15(N° 632-633):101-103

UniversitätsSpital Zürich, Klinik für Konsiliarpsychiatrie und Psychosomatik, Culmannstrasse 8, 8091 Zürich.

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January 2019

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis.

Proc Natl Acad Sci U S A 2018 12 19;115(49):12495-12500. Epub 2018 Nov 19.

Unit for Research in Schizophrenia, Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), CH-1008 Prilly-Lausanne, Switzerland;

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http://dx.doi.org/10.1073/pnas.1812821115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298080PMC
December 2018

Patients participating to neurobiological research in early psychosis: A selected subgroup?

Schizophr Res 2018 11 26;201:249-253. Epub 2018 Apr 26.

Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland.

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http://dx.doi.org/10.1016/j.schres.2018.04.033DOI Listing
November 2018

[Coordination meeting during psychiatric hospitalization : expectations, challenges and solutions].

Rev Med Suisse 2018 Sep;14(619):1637-1641

Direction, Département de psychiatrie, CHUV, 1011 Lausanne.

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September 2018

Quantifying the Effects of 16p11.2 Copy Number Variants on Brain Structure: A Multisite Genetic-First Study.

Biol Psychiatry 2018 08 27;84(4):253-264. Epub 2018 Mar 27.

Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; CHU Sainte-Justine Research Center, Université de Montréal, Montréal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.02.1176DOI Listing
August 2018

Second-Generation Antipsychotics in Adolescent Psychiatric Patients: Metabolic Effects and Impact of an Early Weight Change to Predict Longer Term Weight Gain.

J Child Adolesc Psychopharmacol 2018 05 3;28(4):258-265. Epub 2018 Jan 3.

2 Interdisciplinary Division for Adolescent Health (DISA), Lausanne University Hospital , Lausanne, Switzerland .

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http://dx.doi.org/10.1089/cap.2017.0038DOI Listing
May 2018

'Is "early intervention" in bipolar disorder what it claims to be?' Malhi et al.

Bipolar Disord 2018 05;20(3):181-183

Treatment and Early Intervention in Psychosis Program (TIPP), Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1111/bdi.12641DOI Listing
May 2018

[Insight and Violent Behavior in a Cohort of Early Psychosis Patients].

Can J Psychiatry 2018 01 28;63(1):20-29. Epub 2017 Jun 28.

4 Service de Psychiatrie Générale, Département de Psychiatrie du Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.

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http://dx.doi.org/10.1177/0706743717718173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788119PMC
January 2018

Treatment in early psychosis with N-acetyl-cysteine for 6months improves low-level auditory processing: Pilot study.

Schizophr Res 2018 01 12;191:80-86. Epub 2017 Jul 12.

The LINE (Laboratory for Investigative Neurophysiology), Radiodiagnostic Service, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland; Neuropsychology and Neurorehabilitation Service and Radiodiagnostic Service, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland; The EEG Brain Mapping Core, Center for Biomedical Imaging (CIBM), University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland; Department of Ophthalmology, University of Lausanne, Fondation Asile des Aveugles, Lausanne, Switzerland; Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.07.008DOI Listing
January 2018

Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex.

Psychopharmacology (Berl) 2018 01 26;235(1):13-22. Epub 2017 Oct 26.

TIPP (Treatment and Early Intervention in Psychosis Program); Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://link.springer.com/10.1007/s00213-017-4745-z
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http://dx.doi.org/10.1007/s00213-017-4745-zDOI Listing
January 2018

[Psychiatry].

Rev Med Suisse 2018 Jan;14(588-589):90-92

Service de psychiatrie communautaire, Département de psychiatrie, CHUV, 1011 Lausanne.

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January 2018

The coupling of low-level auditory dysfunction and oxidative stress in psychosis patients.

Schizophr Res 2017 12 9;190:52-59. Epub 2017 Feb 9.

Neuropsychology and Neurorehabilitation Service, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland; Radiodiagnostic Service, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland; The EEG Brain Mapping Core, Center for Biomedical Imaging (CIBM), University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland; Psychiatric Liaison Service, Lausanne University Hospital (CHUV), Lausanne, Switzerland; Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Lausanne, Switzerland; Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.02.002DOI Listing
December 2017

Influence of polygenic risk scores on lipid levels and dyslipidemia in a psychiatric population receiving weight gain-inducing psychotropic drugs.

Pharmacogenet Genomics 2017 Dec;27(12):464-472

aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Centre of Psychiatric Epidemiology and Psychopathology cDepartment of Psychiatry, Service of Old Age Psychiatry dDepartment of Psychiatry, Service of General Psychiatry, Lausanne University Hospital, Prilly eSchool of Pharmaceutical Sciences, University of Geneva-Lausanne, Geneva, Switzerland.

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http://dx.doi.org/10.1097/FPC.0000000000000313DOI Listing
December 2017

Mild Depressive Symptoms Mediate the Impact of Childhood Trauma on Long-Term Functional Outcome in Early Psychosis Patients.

Schizophr Bull 2017 09;43(5):1027-1035

Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1093/schbul/sbw163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581905PMC
September 2017

Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.

Soc Psychiatry Psychiatr Epidemiol 2017 09 5;52(9):1089-1099. Epub 2017 May 5.

Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00127-017-1388-7DOI Listing
September 2017

Social and academic premorbid adjustment domains predict different functional outcomes among youth with first episode mania.

J Affect Disord 2017 09 20;219:133-140. Epub 2017 May 20.

Orygen, the National Centre of Excellence in Youth Mental Health, Parkville, Australia; Centre for Youth Mental Health, University of Melbourne, Australia.

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http://dx.doi.org/10.1016/j.jad.2017.05.030DOI Listing
September 2017

Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs.

Gene 2017 Sep 8;628:8-15. Epub 2017 Jul 8.

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.07.005DOI Listing
September 2017

[Recovering the capacity to live outside of hospital : results from a specialized inpatient program].

Rev Med Suisse 2017 Sep;13(575):1610-1613

Service de psychiatrie générale, Département de psychiatrie, CHUV, 1011 Lausanne.

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September 2017

Community Treatment Order: Identifying the need for more evidence based justification of its use in first episode psychosis patients.

Schizophr Res 2017 07 27;185:67-72. Epub 2016 Dec 27.

Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), University Hospital of Lausanne (CHUV), Place Chauderon 18, 1003 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.12.022DOI Listing
July 2017

Predictors of favourable outcome in young people with a first episode psychosis without antipsychotic medication.

Schizophr Res 2017 07 6;185:130-136. Epub 2017 Jan 6.

Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1016/j.schres.2016.12.029DOI Listing
July 2017

[Case Formulation in Early Psychosis: What are the Tools for Teamwork?]

Can J Psychiatry 2017 07 30;62(7):457-464. Epub 2017 May 30.

1 Service de Psychiatrie Générale, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.

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http://dx.doi.org/10.1177/0706743717703641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528987PMC
July 2017

Quetiapine lithium in the maintenance phase following a first episode of mania: randomised controlled trial.

Br J Psychiatry 2017 06 2;210(6):413-421. Epub 2017 Mar 2.

Michael Berk, MBBCh, PhD, Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health and the Geelong Clinic; Orygen, The National Centre of Excellence in Youth Mental Health, the Florey Institute for Neuroscience and Mental Health and the Department of Psychiatry, University of Melbourne, Victoria, Australia; Rothanthi Daglas, DPsych, Orygen, The National Centre of Excellence in Youth Mental Health and the Centre for Youth Mental Health, University of Melbourne, Victoria, Australia; Orwa Dandash, PhD, Murat Yücel, PhD, Brain and Mental Health Laboratory, Monash Institute of Cognitive and Clinical Neurosciences (MICCN), School of Psychological Sciences, Monash University, Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia; Lisa Henry, MPsych, Orygen, The National Centre of Excellence in Youth Mental Health and the Centre for Youth Mental Health, University of Melbourne, Victoria, Australia; Karen Hallam, PhD, Division of Psychology, School of Health and Biomedical Science, RMIT University, Melbourne, Victoria, Australia; Craig Macneil, DPsych, Melissa Hasty, DPsych, Orygen, The National Centre of Excellence in Youth Mental Health and the Centre for Youth Mental Health, University of Melbourne, Victoria, Australia; Christos Pantelis, MD, Hon MD (Athens), Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Carlton South, Victoria, Australia; Brendan P. Murphy, FRCPsych, Department of Psychiatry, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia; Linda Kader, MD, Orygen, The National Centre of Excellence in Youth Mental Health and the Centre for Youth Mental Health, University of Melbourne, Victoria, Australia; Saji Damodaran, MD, Michael T. H. Wong, MD, PhD, Department of Psychiatry, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia; Philippe Conus, MD, Département Universitaire de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, Prilly, Switzerland; Aswin Ratheesh, MD, Patrick D. McGorry, MD, PhD, Sue M. Cotton, PhD, Orygen, The National Centre of Excellence in Youth Mental Health and the Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1192/bjp.bp.116.186833DOI Listing
June 2017

[Stigmatisation : a widespread problem with multiple consequences].

Rev Med Suisse 2017 Feb;13(551):478-481

Service de psychiatrie générale, Département de psychiatrie, CHUV, 1011 Lausanne.

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February 2017

[New developments in psychiatry].

Rev Med Suisse 2017 Jan;13(544-545):102-104

Service universitaire de psychiatrie de l'âge avancé, Département de psychiatrie, CHUV, 1011 Lausanne.

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January 2017

Prediction of early weight gain during psychotropic treatment using a combinatorial model with clinical and genetic markers.

Pharmacogenet Genomics 2016 Dec;26(12):547-557

aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Center for Psychiatric Epidemiology and Psychopathology cDepartment of Psychiatry, Service of Old Age Psychiatry dDepartment of Psychiatry, Service of General Psychiatry, Lausanne University Hospital, Hospital of Cery, Prilly eDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Geneva, University of Lausanne, Geneva, Switzerland.

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http://dx.doi.org/10.1097/FPC.0000000000000249DOI Listing
December 2016

Unpacking 'the City': An experience-based approach to the role of urban living in psychosis.

Health Place 2016 11 15;42:104-110. Epub 2016 Oct 15.

Treatment and Early Intervention in Psychosis Program(TIPP), Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Clinique de Cery, 1008 Prilly, Switzerland.

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http://dx.doi.org/10.1016/j.healthplace.2016.09.002DOI Listing
November 2016

Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis.

Schizophr Bull 2016 09 11;42(5):1185-96. Epub 2016 Apr 11.

Unit for Research in Schizophrenia, Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Lausanne, Switzerland;

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http://dx.doi.org/10.1093/schbul/sbw038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988744PMC
September 2016

Association of CRTC1 polymorphisms with obesity markers in subjects from the general population with lifetime depression.

J Affect Disord 2016 07 10;198:43-9. Epub 2016 Mar 10.

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland. Electronic address:

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http://www.tweelingenregister.org/nederlands/verslaggeving/N
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http://linkinghub.elsevier.com/retrieve/pii/S016503271531310
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http://dx.doi.org/10.1016/j.jad.2016.03.031DOI Listing
July 2016

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression.

PLoS One 2015 13;10(10):e0139155. Epub 2015 Oct 13.

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139155PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604197PMC
June 2016

Duration of untreated psychosis: Impact of the definition of treatment onset on its predictive value over three years of treatment.

J Psychiatr Res 2016 Jun 26;77:15-21. Epub 2016 Feb 26.

Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland.

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http://dx.doi.org/10.1016/j.jpsychires.2016.02.017DOI Listing
June 2016

Trajectory and predictors of quality of life in first episode psychotic mania.

J Affect Disord 2016 May 9;195:148-55. Epub 2016 Feb 9.

Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia; Centre for Youth Mental Health, The University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1016/j.jad.2016.02.018DOI Listing
May 2016

Association of genetic risk scores with body mass index in Swiss psychiatric cohorts.

Pharmacogenet Genomics 2016 May;26(5):208-17

aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Centre of Psychiatric Epidemiology and Psychopathology cService of Old Age Psychiatry, Department of Psychiatry dService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital, Prilly eDepartment of Mental Health and Psychiatry, University Hospital of Geneva fSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva gInstitute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital hSwiss Institute of Bioinformatics, Lausanne, Switzerland.

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http://dx.doi.org/10.1097/FPC.0000000000000210DOI Listing
May 2016

Assertive outreach for "difficult to engage" patients: A useful tool for a subgroup of patients in specialized early psychosis intervention programs.

Psychiatry Res 2016 05 5;239:212-9. Epub 2016 Mar 5.

Service of community Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Switzerland.

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http://dx.doi.org/10.1016/j.psychres.2016.03.010DOI Listing
May 2016

Age at the time of exposure to trauma modulates the psychopathological profile in patients with early psychosis.

J Clin Psychiatry 2016 05;77(5):e612-8

Treatment and Early Intervention in Psychosis Program (TIPP), Rue de Caroline 2, Lausanne, 1003, Switzerland

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http://dx.doi.org/10.4088/JCP.15m09947DOI Listing
May 2016

Genetics-Based Population Pharmacokinetics and Pharmacodynamics of Risperidone in a Psychiatric Cohort.

Clin Pharmacokinet 2015 Dec;54(12):1259-72

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Hospital of Cery, Lausanne University Hospital, 1008, Prilly, Switzerland.

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http://dx.doi.org/10.1007/s40262-015-0289-8DOI Listing
December 2015

Benefits of adjunctive N-acetylcysteine in a sub-group of clozapine-treated individuals diagnosed with schizophrenia.

Psychiatry Res 2015 Dec 2;230(3):982-3. Epub 2015 Nov 2.

IMPACT Strategic Research Centre, Deakin University, Geelong, Australia; Florey Institute for Neuroscience and Mental Health, Parkville, Australia; Department of Psychiatry, University of Melbourne, Parkville, Australia; Barwon Health, Geelong, Australia; Orygen Research Centre, Parkville, Australia.

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https://www.alamaya.net/wp-content/uploads/2015/04/Dean_Psyc
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http://linkinghub.elsevier.com/retrieve/pii/S016517811530605
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http://dx.doi.org/10.1016/j.psychres.2015.10.037DOI Listing
December 2015

Importance of early weight changes to predict long-term weight gain during psychotropic drug treatment.

J Clin Psychiatry 2015 Nov;76(11):e1417-23

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Hospital of Cery, Prilly, Switzerland.

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http://dx.doi.org/10.4088/JCP.14m09358DOI Listing
November 2015

Association of PCK1 with Body Mass Index and Other Metabolic Features in Patients With Psychotropic Treatments.

J Clin Psychopharmacol 2015 Oct;35(5):544-52

From the *Unit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience, †Department of Psychiatry, Centre of Psychiatric Epidemiology and Psychopathology, ‡Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital, Prilly, Switzerland; §Laboratory of Neuroenergetics and Cellular Dynamics, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne; ∥Department of Mental Health and Psychiatry, University Hospital of Geneva, Geneva; ¶Service of Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Prilly; #Department of Medicine, Lausanne University Hospital; **Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital; ††Swiss Institute of Bioinformatics, Lausanne; ‡‡Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital, Prilly; and §§School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.

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http://dx.doi.org/10.1097/JCP.0000000000000388DOI Listing
October 2015

Beyond clinical staging of psychiatric disorders.

Lancet Psychiatry 2015 Oct 29;2(10):e27. Epub 2015 Sep 29.

Treatment and early Intervention in Psychosis Program (TIPP), Consultation de Chauderon, 1003 Lausanne, Switzerland; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/S2215-0366(15)00377-6DOI Listing
October 2015

An evidence map of psychosocial interventions for the earliest stages of bipolar disorder.

Lancet Psychiatry 2015 Jun 27;2(6):548-63. Epub 2015 May 27.

Academic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK; Centre for Affective Disorders, IPPN, King's College, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(15)00156-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629930PMC
June 2015

The impact of insight in a first-episode mania with psychosis population on outcome at 18 months.

J Affect Disord 2014 2;167:74-9. Epub 2014 Jun 2.

Treatment and early Intervention in Psychosis Program (TIPP), Service de Psychiatrie Générale, Département de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, 1008 Prilly, Switzerland.

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http://dx.doi.org/10.1016/j.jad.2014.05.055DOI Listing
May 2015

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments.

Pharmacogenet Genomics 2015 May;25(5):246-58

aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Centre of Psychiatric Epidemiology and Psychopathology cDepartment of Psychiatry, Service of Old Age Psychiatry dDepartment of Psychiatry, Service of General Psychiatry, Lausanne University Hospital, Prilly eLaboratory of Neuroenergetics and Cellular Dynamics, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne fDepartment of Medicine gInstitute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital hDepartment of Medical Genetics, University of Lausanne iSwiss Institute of Bioinformatics, Lausanne jDepartment of Mental Health and Psychiatry, University Hospital of Geneva kSchool of Pharmaceutical Sciences, University of Geneve, University of Lausanne, Geneva, Switzerland lFaculty of Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.

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http://dx.doi.org/10.1097/FPC.0000000000000131DOI Listing
May 2015

Developing psychosis and its risk states through the lens of schizotypy.

Schizophr Bull 2015 Mar 29;41 Suppl 2:S396-407. Epub 2014 Dec 29.

University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1093/schbul/sbu176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373628PMC
March 2015

History of offending behavior in first episode psychosis patients: a marker of specific clinical needs and a call for early detection strategies among young offenders.

Schizophr Res 2015 Feb 20;161(2-3):163-8. Epub 2014 Nov 20.

Treatment and Early Intervention in Psychosis Program(TIPP), Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Clinique de Cery, 1008 Prilly, Switzerland; Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1016/j.schres.2014.09.078DOI Listing
February 2015

Characterizing the connectome in schizophrenia with diffusion spectrum imaging.

Hum Brain Mapp 2015 Jan 12;36(1):354-66. Epub 2014 Sep 12.

Signal Processing Laboratory 5 (LTS5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; Department of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.

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http://dx.doi.org/10.1002/hbm.22633DOI Listing
January 2015

Predictors of substance use reduction in an epidemiological first-episode psychosis cohort.

Early Interv Psychiatry 2014 Nov 24;8(4):358-65. Epub 2013 Jul 24.

Institute of Health & Biomedical Innovation and School of Psychology & Counselling, Queensland University of Technology, Brisbane; Queensland Health, Metro-North Health Service District, Redcliffe-Caboolture Mental Health Service, Caboolture, Queensland, Australia.

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http://dx.doi.org/10.1111/eip.12067DOI Listing
November 2014

The impact of past direct-personal traumatic events on 12-month outcome in first episode psychotic mania: trauma and early psychotic mania.

Aust N Z J Psychiatry 2014 Nov 13;48(11):1017-24. Epub 2014 Aug 13.

Department of Psychology, Victoria University, Melbourne, Australia.

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http://dx.doi.org/10.1177/0004867414545672DOI Listing
November 2014

Impaired metabolic reactivity to oxidative stress in early psychosis patients.

Schizophr Bull 2014 Sep 31;40(5):973-83. Epub 2014 Mar 31.

Department of Psychiatry, Unit for Research in Schizophrenia, Center for Psychiatric Neuroscience, Lausanne University Hospital (CHUV), Lausanne, Switzerland;

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http://schizophreniabulletin.oxfordjournals.org/content/40/5
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http://dx.doi.org/10.1093/schbul/sbu053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133680PMC
September 2014

[Family physicians and psychiatrists' collaborative care for mental health problems].

Rev Med Suisse 2014 Sep;10(442):1715-8

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September 2014

Stage managing bipolar disorder.

Bipolar Disord 2014 Aug 20;16(5):471-7. Epub 2013 Jun 20.

School of Medicine, Deakin University, Geelong; Department of Psychiatry, University of Melbourne, Melbourne, Vic., Australia; Orygen Youth Health, Melbourne, Vic., Australia; Florey Institute for Neuroscience and Mental Health, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/bdi.12099DOI Listing
August 2014

Public health significance of bipolar disorder: implications for early intervention and prevention.

Bipolar Disord 2014 Aug 16;16(5):548-56. Epub 2013 Oct 16.

Service de Psychiatrie Générale, Département Universitaire de Psychiatrie CHUV, Lausanne University, Clinique de Cery, Prilly, Switzerland.

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http://dx.doi.org/10.1111/bdi.12137DOI Listing
August 2014

Pharmacogenetic study on risperidone long-acting injection: influence of cytochrome P450 2D6 and pregnane X receptor on risperidone exposure and drug-induced side-effects.

J Clin Psychopharmacol 2013 Jun;33(3):289-98

Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, University Hospital Centre and University of Lausanne, Prilly, Switzerland.

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http://dx.doi.org/10.1097/JCP.0b013e31828f62cdDOI Listing
June 2013

Gender differences in first episode psychotic mania.

BMC Psychiatry 2013 Mar 13;13:82. Epub 2013 Mar 13.

Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 (35 Poplar Road), Parkville, Victoria, 3052, Australia.

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http://dx.doi.org/10.1186/1471-244X-13-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602146PMC
March 2013

Can a targeted psychological intervention be effective for young people following a first manic episode? Results from an 18-month pilot study.

Early Interv Psychiatry 2012 Nov 8;6(4):380-8. Epub 2012 Jan 8.

Early Psychosis Prevention and Intervention Centre (EPPIC) Continuing Care Team, Orygen Youth Health Clinical Program, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1751-7893.2011.00336.xDOI Listing
November 2012

Differentiating schizoaffective and bipolar I disorder in first-episode psychotic mania.

Schizophr Res 2012 Sep 28;140(1-3):31-6. Epub 2012 Jul 28.

Psychosis Early Detection and Intervention Centre-PEDIC, Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Medical Centre Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1016/j.schres.2012.07.010DOI Listing
September 2012

Is diagnosis enough to guide interventions in mental health? Using case formulation in clinical practice.

BMC Med 2012 Sep 27;10:111. Epub 2012 Sep 27.

Early Psychosis Prevention & Intervention Centre (EPPIC), and Orygen Youth Health Research Centre, Orygen Youth Health, 35 Poplar Road, Parkville, Melbourne, Victoria, 3052, Australia.

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http://dx.doi.org/10.1186/1741-7015-10-111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523045PMC
September 2012

Addition of aripiprazole to the clozapine may be useful in reducing anxiety in treatment-resistant schizophrenia.

Case Rep Psychiatry 2011 14;2011:846489. Epub 2011 Sep 14.

Department of Psychiatry, Centre Hospitalier Universitaire Vaudois, Section Eugene Minkowski, Site de Cery, 1008 Prilly, Switzerland.

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http://dx.doi.org/10.1155/2011/846489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420713PMC
August 2012

The Swiss Early Psychosis Project SWEPP: a national network.

Early Interv Psychiatry 2012 Feb 10;6(1):106-11. Epub 2012 Jan 10.

University Hospital of Psychiatry, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1111/j.1751-7893.2011.00322.xDOI Listing
February 2012

High b-value diffusion-weighted imaging: a sensitive method to reveal white matter differences in schizophrenia.

Psychiatry Res 2012 Feb 3;201(2):144-51. Epub 2012 Mar 3.

Department of Psychiatry, University Hospital Center and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.pscychresns.2011.08.003DOI Listing
February 2012

Duration of untreated psychosis: a proposition regarding treatment definition.

Early Interv Psychiatry 2011 Nov;5(4):301-8

Treatment and Early Intervention in Psychosis Program (TIPP) Centre for Psychiatric Neuroscience, Department of Psychiatry, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1111/j.1751-7893.2011.00308.xDOI Listing
November 2011

Motivational intervention to reduce cannabis use in young people with psychosis: a randomized controlled trial.

Psychother Psychosom 2011 1;80(5):287-97. Epub 2011 Jun 1.

CHUV Lausanne, Site de Cery, Unité de réhabilitation, Bâtiment des Cèdres, Prilly, Switzerland.

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http://dx.doi.org/10.1159/000323466DOI Listing
October 2011

[The "SYNAPSY" project: where psychiatrists and neuroscientists meet].

Rev Med Suisse 2011 Sep;7(309):1818-20, 1822-3

Service de Psychiatrie Générale, Département de Psychiatrie CHUV, Site de Cery, 1008 Prilly.

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September 2011

Qualitative methods in early-phase drug trials: broadening the scope of data and methods from an RCT of N-acetylcysteine in schizophrenia.

J Clin Psychiatry 2011 Jul 21;72(7):909-13. Epub 2010 Sep 21.

Department of Clinical and Biomedical Sciences: Barwon Health, University of Melbourne, PO Box 281, Geelong 3220, Victoria, Australia.

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http://dx.doi.org/10.4088/JCP.09m05741yelDOI Listing
July 2011

Cannabis use disorder and age at onset of psychosis--a study in first-episode patients.

Schizophr Res 2011 Jun 17;129(1):52-6. Epub 2011 Apr 17.

University Hospital of Child and Adolescent Psychiatry, Bern, Switzerland.

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http://dx.doi.org/10.1016/j.schres.2011.03.023DOI Listing
June 2011

[Psychiatry].

Rev Med Suisse 2011 Jan;7(278):150-3

Département de psychiatrie, CHUV, Lausanne.

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January 2011