Publications by authors named "Philippe Clézardin"

100Publications

Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions.

Authors:
Francesco Pantano Martine Croset Keltouma Driouch Natalia Bednarz-Knoll Michele Iuliani Giulia Ribelli Edith Bonnelye Harriet Wikman Sandra Geraci Florian Bonin Sonia Simonetti Bruno Vincenzi Saw See Hong Sofia Sousa Klaus Pantel Giuseppe Tonini Daniele Santini Philippe Clézardin

Oncogene 2021 Jan 8. Epub 2021 Jan 8.

INSERM, UMR_S1033, LYOS, Lyon, France.

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January 2021

Bone Metastasis: Mechanisms, Therapies and Biomarkers.

Authors:
Philippe Clezardin Rob Coleman Margherita Puppo Penelope Ottewell Edith Bonnelye Frédéric Paycha Cyril B Confavreux Ingunn Holen

Physiol Rev 2020 Dec 24. Epub 2020 Dec 24.

Oncology and Metabolism, University of Sheffield, United Kingdom.

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December 2020

Bone metastases.

Authors:
Robert E Coleman Peter I Croucher Anwar R Padhani Philippe Clézardin Edward Chow Marie Fallon Theresa Guise Simone Colangeli Rodolfo Capanna Luis Costa

Nat Rev Dis Primers 2020 10 15;6(1):83. Epub 2020 Oct 15.

Hospital de Santa Maria and Instituto de Medicina Molecular, Faculdade de Medicina, Centro Hospitalar de Lisboa Norte, Lisbon, Portugal.

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October 2020

Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay.

Authors:
Caterina F Donini Myriam El Helou Anne Wierinckx Balázs Győrffy Sophie Aires Aurélie Escande Séverine Croze Philippe Clezardin Joël Lachuer Mona Diab-Assaf Sandra E Ghayad Béatrice Fervers Vincent Cavaillès Véronique Maguer-Satta Pascale A Cohen

Front Oncol 2020 29;10:712. Epub 2020 May 29.

Université Lyon 1, Lyon, France.

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May 2020

ERRα Expression in Bone Metastases Leads to an Exacerbated Antitumor Immune Response.

Authors:
Mathilde Bouchet Alexandra Lainé Cyril Boyault Mathilde Proponnet-Guerault Emmanuelle Meugnier Lamia Bouazza Casina W S Kan Sandra Geraci Soumaya El-Moghrabi Hector Hernandez-Vargas Claire Benetollo Yuji Yoshiko Martine Duterque-Coquillaud Philippe Clézardin Julien C Marie Edith Bonnelye

Cancer Res 2020 07 4;80(13):2914-2926. Epub 2020 May 4.

INSERM-UMR1033, Labex DEVweCAN, Lyon, France.

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July 2020

The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases.

Authors:
Souvik Das Philippe Clézardin Said Kamel Michel Brazier Romuald Mentaverri

Front Oncol 2020 5;10:69. Epub 2020 Feb 5.

MP3CV, EA7517, CURS, University of Picardie Jules Verne, Amiens, France.

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February 2020

Non-coding RNAs in bone remodelling and bone metastasis: Mechanisms of action and translational relevance.

Authors:
Margherita Puppo Hanna Taipaleenmäki Eric Hesse Philippe Clézardin

Br J Pharmacol 2019 Aug 18. Epub 2019 Aug 18.

Department of Oncology and Metabolism, Medical School, University of Sheffield, Sheffield, UK.

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August 2019

Bone metastases in the era of targeted treatments: insights from molecular biology.

Authors:
Jonatan Dewulf Christel Vangestel Yannick Verhoeven Peter van Dam Filipe Elvas Tim Van den Wyngaert Philippe Clézardin

Q J Nucl Med Mol Imaging 2019 Jun 11;63(2):98-111. Epub 2019 Jul 11.

INSERM Laboratory Pathophysiology, Diagnosis and Treatments of Bone Diseases, Lyon, France.

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June 2019

TMPRSS2:ERG gene fusion expression regulates bone markers and enhances the osteoblastic phenotype of prostate cancer bone metastases.

Authors:
Carine Delliaux Tian V Tian Mathilde Bouchet Anais Fradet Nathalie Vanpouille Anne Flourens Rachel Deplus Arnauld Villers Xavier Leroy Philippe Clézardin Yvan de Launoit Edith Bonnelye Martine Duterque-Coquillaud

Cancer Lett 2018 12 7;438:32-43. Epub 2018 Sep 7.

Univ. Lille, CNRS, Institut Pasteur de Lille, UMR 8161 - Mechanisms of Tumorigenesis and Target Therapies, F-59021, Lille, France. Electronic address:

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December 2018

Comparative Study of Neoadjuvant Chemotherapy With and Without Zometa for Management of Locally Advanced Breast Cancer With Serum VEGF as Primary Endpoint: The NEOZOL Study.

Authors:
Loïc Lelièvre Philippe Clézardin Laurent Magaud Laurent Roche Nicole Tubiana-Mathieu Jean-Dominique Tigaud Delphine Topart Nadia Raban Marie-Ange Mouret-Reynier Patrice Mathevet

Clin Breast Cancer 2018 12 10;18(6):e1311-e1321. Epub 2018 Jul 10.

Centre du sein, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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December 2018

miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis-Associated Genes.

Authors:
Martine Croset Francesco Pantano Casina W S Kan Edith Bonnelye Françoise Descotes Catherine Alix-Panabières Charles-Henri Lecellier Richard Bachelier Nathalie Allioli Saw-See Hong Kai Bartkowiak Klaus Pantel Philippe Clézardin

Cancer Res 2018 09 24;78(18):5259-5273. Epub 2018 Jul 24.

INSERM, UMR_S1033, University Lyon 1, Lyon, France.

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September 2018

The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis.

Authors:
Evelyne Gineyts Nicolas Bonnet Cindy Bertholon Marjorie Millet Aurélie Pagnon-Minot Olivier Borel Sandra Geraci Edith Bonnelye Martine Croset Ali Suhail Cristina Truica Nicholas Lamparella Kim Leitzel Daniel Hartmann Roland Chapurlat Allan Lipton Patrick Garnero Serge Ferrari Philippe Clézardin Jean-Charles Rousseau

Calcif Tissue Int 2018 11 18;103(5):567-580. Epub 2018 Jun 18.

INSERM 1033, Pavillon F, Hôpital Edouard Herriot, Lyon, 69437, France.

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November 2018

Bone, muscle, and metabolic parameters predict survival in patients with synchronous bone metastases from lung cancers.

Authors:
Lauriane Chambard Nicolas Girard Edouard Ollier Jean-Charles Rousseau François Duboeuf Marie-Christine Carlier Marie Brevet Pawel Szulc Jean-Baptiste Pialat Julien Wegrzyn Philippe Clezardin Cyrille B Confavreux

Bone 2018 03 11;108:202-209. Epub 2018 Jan 11.

INSERM UMR1033-LYOS, Université de Lyon, Lyon F-69003, France; Rheumatology Department, Hospices Civils de Lyon, Pierre-Bénite F-69495, France. Electronic address:

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March 2018

Bone-Targeted Therapies in Cancer-Induced Bone Disease.

Authors:
Sofia Sousa Philippe Clézardin

Calcif Tissue Int 2018 02 27;102(2):227-250. Epub 2017 Oct 27.

National Institute of Health and Medical Research (INSERM), UMR 1033, 69372, Lyon, France.

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February 2018

Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation.

Authors:
Cédric Boudot Lucie Hénaut Ursula Thiem Sandra Geraci Mariangela Galante Paulo Saldanha Zuzana Saidak Isabelle Six Philippe Clézardin Said Kamel Romuald Mentaverri

Oncotarget 2017 Aug 10;8(34):56460-56472. Epub 2017 Apr 10.

Inserm U1088, Centre Universitaire de Recherche en Santé, Université de Picardie Jules Verne, Amiens, France.

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August 2017

Pathophysiology of bone metastases from solid malignancies.

Authors:
Philippe Clézardin

Joint Bone Spine 2017 Dec 9;84(6):677-684. Epub 2017 May 9.

Inserm, UMR 1033, UFR de médecine Lyon-Est, 69372 Lyon cedex 08, France; Université Claude-Bernard Lyon-1, 69622 Villeurbanne, France. Electronic address:

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December 2017

Cancer Cell Colonisation in the Bone Microenvironment.

Authors:
Casina Kan Geoffrey Vargas François Le Pape Philippe Clézardin

Int J Mol Sci 2016 Oct 4;17(10). Epub 2016 Oct 4.

National Institute of Health and Medical Research (INSERM), UMR 1033, Lyon 69372, France.

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October 2016

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone.

Authors:
Anais Fradet Mathilde Bouchet Carine Delliaux Manon Gervais Casina Kan Claire Benetollo Francesco Pantano Geoffrey Vargas Lamia Bouazza Martine Croset Yohann Bala Xavier Leroy Thomas J Rosol Jennifer Rieusset Akeila Bellahcène Vincent Castronovo Jane E Aubin Philippe Clézardin Martine Duterque-Coquillaud Edith Bonnelye

Oncotarget 2016 11;7(47):77071-77086

InsermUMR1033, F-69372 Lyon, France.

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November 2016

The role of osteoclasts in breast cancer bone metastasis.

Authors:
François Le Pape Geoffrey Vargas Philippe Clézardin

J Bone Oncol 2016 Sep 8;5(3):93-95. Epub 2016 Apr 8.

INSERM, UMR 1033, Lyon F-69372, France; Université Lyon-1, Villeurbanne F-69622, France.

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September 2016

Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone.

Authors:
Caroline Reynaud Laura Ferreras Paola Di Mauro Casina Kan Martine Croset Edith Bonnelye Floriane Pez Clémence Thomas Géraldine Aimond Antoine E Karnoub Marie Brevet Philippe Clézardin

Cancer Res 2017 01 14;77(2):268-278. Epub 2016 Oct 14.

INSERM, UMR1033, Lyon, France.

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January 2017