Publications by authors named "Philippe Chan"

43Publications

Strategies for the Identification of Bioactive Neuropeptides in Vertebrates.

Front Neurosci 2019 18;13:948. Epub 2019 Sep 18.

Normandie Univ, UNIROUEN, Inserm, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Neuropeptides, Neuronal Death and Cell Plasticity Team, Rouen, France.

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September 2019

Proteome modifications of gut microbiota in mice with activity-based anorexia and starvation: Role in ATP production.

Nutrition 2019 Nov - Dec;67-68:110557. Epub 2019 Aug 5.

Normandie University, UNIROUEN, Nutrition, Gut and Brain Laboratory Rouen, France; Normandie University, UNIROUEN, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France. Electronic address:

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October 2020

Colonic Proteome Signature in Immunoproteasome-Deficient Stressed Mice and Its Relevance for Irritable Bowel Syndrome.

J Proteome Res 2019 01 26;18(1):478-492. Epub 2018 Nov 26.

INSERM unit 1073 , Normandie University, UNIROUEN , 22 boulevard Gambetta , Rouen , F-76183 , France.

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January 2019

Highly polluted life history and acute heat stress, a hazardous mix for blue mussels.

Mar Pollut Bull 2018 Oct 27;135:594-606. Epub 2018 Jul 27.

Laboratory of Ecotoxicology, UMR-I 02 SEBIO, Le Havre University, Normandy University, France.

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October 2018

A Peptidomic Approach to Characterize Peptides Involved in Cerebellar Cortex Development Leads to the Identification of the Neurotrophic Effects of Nociceptin.

Mol Cell Proteomics 2018 09 12;17(9):1737-1749. Epub 2018 Jun 12.

From the ‡Normandie Univ, UNIROUEN, Inserm, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Neuropeptides, Neuronal death and Cell plasticity team, 76000 Rouen, France;

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September 2018

Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition.

J Mol Cell Biol 2018 06;10(3):229-242

Molecular Medicine Laboratory, Institute of Biomedical and Biomolecular Sciences, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.

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June 2018

Redox Proteomics Applied to the Thiol Secretome.

Antioxid Redox Signal 2017 03 7;26(7):299-312. Epub 2016 Jun 7.

2 PISSARO Proteomic Platform, Institute for Research and Innovation in Biomedicine, University of Rouen , Rouen, France .

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March 2017

Consequences of acclimation on the resistance to acute thermal stress: Proteomic focus on mussels from pristine site.

Mar Environ Res 2016 Oct 27;121:64-73. Epub 2016 Feb 27.

Laboratory of Ecotoxicology, UMR-I 02 SEBIO, Le Havre University, Normandy University, France.

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October 2016

Unraveling the effects of static magnetic field stress on cytosolic proteins of Salmonella by using a proteomic approach.

Can J Microbiol 2016 Apr 21;62(4):338-48. Epub 2015 Dec 21.

a Laboratoire de Biochimie et Biologie Moléculaire, Faculté des Sciences de Bizerte, Université de Carthage, 7021 Zarzouna, Bizerte, Tunisie.

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April 2016

Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth.

Cell Metab 2016 Feb 24;23(2):324-34. Epub 2015 Nov 24.

Inserm UMR1073, Nutrition, Gut and Brain Laboratory, Rouen 76183, France; Institute for Research and Innovation in Biomedicine (IRIB), Rouen University, Normandy University, Rouen 76000, France. Electronic address:

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February 2016

Biochemical Characterization of Human Anti-Hepatitis B Monoclonal Antibody Produced in the Microalgae Phaeodactylum tricornutum.

PLoS One 2015 5;10(10):e0139282. Epub 2015 Oct 5.

Laboratoire Glycobiologie et Matrice Extracellulaire végétale Equipe d'Accueil 4358, Faculté des sciences et techniques, Université de Rouen, Normandie Université, Institut de Recherche et d'Innovation Biomédicale, Végétale Agronomie Sol Innovation, Mont-Saint-Aignan, France; Institut Universitaire de France, Paris, France.

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June 2016

Development of 'Redox Arrays' for identifying novel glutathionylated proteins in the secretome.

Sci Rep 2015 Sep 29;5:14630. Epub 2015 Sep 29.

Brighton and Sussex Medical School, Trafford Centre for Medical Research, Falmer, Brighton BN1 9RY UK.

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September 2015

A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.

Autophagy 2015 ;11(1):113-30

a Molecular Medicine Laboratory; Institute of Biomedical and Biomolecular Sciences; School of Pharmacy and Biomedical Sciences ; University of Portsmouth ; Portsmouth , UK.

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November 2015

2-DE Mapping of the Blue Mussel Gill Proteome: The Usual Suspects Revisited.

Proteomes 2015 Jan 12;3(1):3-41. Epub 2015 Jan 12.

Laboratory of Ecotoxicology-Aquatic Environments, UMR I-02 SEBIO, Le Havre University, 76063 Le Havre, France.

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January 2015

Proteomic profile of pre - B2 lymphoblasts from children with acute lymphoblastic leukemia (ALL) in relation with the translocation (12; 21).

Clin Proteomics 2014 1;11(1):31. Epub 2014 Aug 1.

Laboratoire MERCI, Faculté de Médecine et de Pharmacie de Rouen, 123 boulevard Gambetta, Rouen, Cedex 76183, France ; Service d'Immuno-Hématologie Onco-pédiatrique du CHRU de Rouen, Hôpital Charles Nicolle, Rouen 76031, France.

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August 2014

Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist.

J Med Chem 2012 Sep 17;55(17):7516-24. Epub 2012 Aug 17.

Laboratory of Neuronal and Neuroendocrine Differentiation and Communication, Institute for Research and Innovation in Biomedicine (IRIB), INSERM U982, 76821 Mont-Saint-Aignan, France.

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September 2012

Adaptation of Salmonella enterica Hadar under static magnetic field: effects on outer membrane protein pattern.

Proteome Sci 2012 Feb 3;10(1). Epub 2012 Feb 3.

Laboratoire de Biochimie et Biologie Moléculaire, Faculté des Sciences de Bizerte, Université de Carthage, Zarzouna, Bizerte, Tunisie.

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February 2012

Analysis of LuPME3, a pectin methylesterase from Linum usitatissimum, revealed a variability in PME proteolytic maturation.

Plant Signal Behav 2012 Jan;7(1):59-61

Laboratoire Glycobiologie et Matrice Extracellulaire Végétale, EA 4358, IFRMP 23, Université de Rouen, Mont-Saint-Aignan, France.

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January 2012

Impact of toxicant exposure on the proteomic response to intertidal condition in Mytilus edulis.

Comp Biochem Physiol Part D Genomics Proteomics 2011 Dec 16;6(4):357-69. Epub 2011 Aug 16.

Laboratoire d'Ecotoxicologie-Milieux Aquatiques (UPRES EA3222), Faculté des Sciences et Techniques du Havre, 25 rue Philippe Lebon, 76058 Le Havre, France.

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December 2011

Involvement of stathmin 1 in the neurotrophic effects of PACAP in PC12 cells.

J Neurochem 2010 Sep 16;114(5):1498-510. Epub 2010 Jun 16.

INSERM U982, Institut Fédératif de Recherches Multidisciplinaires sur les Peptides (IFRMP 23), Université de Rouen, Mont-Saint-Aignan, France.

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September 2010

Protective DNA vaccination against myelin oligodendrocyte glycoprotein is overcome by C3d in experimental autoimmune encephalomyelitis.

Mol Immunol 2007 Jul 22;44(15):3691-701. Epub 2007 May 22.

INSERM U413, IFRMP 23, Laboratory of Cellular and Molecular Neuroendocrinology, University of Rouen, 76821 Mont Saint-Aignan, France.

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July 2007

C3d binding to the myelin oligodendrocyte glycoprotein results in an exacerbated experimental autoimmune encephalomyelitis.

J Immunol 2007 Mar;178(5):3323-31

INSERM U413, Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23, University of Rouen, Place Emile Blondel, Mont Saint-Aignan Cedex, France.

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March 2007

Identification of proteins regulated by PACAP in PC12 cells by 2D gel electrophoresis coupled to mass spectrometry.

Ann N Y Acad Sci 2006 Jul;1070:380-7

INSERM U413, Laboratory of Cellular and Molecular Neuroendocrinology, European Institute for Peptide Research (IFRMP 23), University of Rouen, 76821 Mont-Saint-Aignan, France.

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July 2006

The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways.

J Neurochem 2006 Jul;98(2):321-9

Laboratory of Cellular and Molecular Neuroendocrinology, European Institute for Peptide Research, University of Rouen, Mont-Saint-Aignan, France.

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July 2006

Interleukin-1beta and anaphylatoxins exert a synergistic effect on NGF expression by astrocytes.

J Neuroinflammation 2006 Apr 4;3. Epub 2006 Apr 4.

Institut Fédératif de Recherche Multidisciplinaire sur les Peptides no23, INSERM U413, Faculté des Sciences, 76130 Mont-St-Aignan, France.

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April 2006

Complement component anaphylatoxins upregulate chemokine expression by human astrocytes.

FEBS Lett 2003 Feb;537(1-3):17-22

Institut Fédératif de Recherche Multidisciplinaire sur les Peptides No. 23, INSERM U519, Faculté Mixte de Médecine et de Pharmacie, 22 Boulevard Gambetta, 76183 Rouen Cedex, France.

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February 2003