Publications by authors named "Philippe A Cassier"

60Publications

Autophagy as a therapeutic target in pancreatic cancer.

Br J Cancer 2020 Sep 15. Epub 2020 Sep 15.

Department of Medical Oncology, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1038/s41416-020-01039-5DOI Listing
September 2020

Efficacy of Selpercatinib in Fusion-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2020 08;383(9):813-824

From Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College (A.D., E.R.) and New York University Langone Medical Center (V.V.), New York, and Roswell Park Comprehensive Cancer Center, Buffalo (G.K.D.) - all in New York; Dana-Farber Cancer Institute (G.R.O.) and Massachusetts General Hospital (J.G.), Boston; National Cancer Centre Singapore, Singapore (D.S.W.T.); the Chinese University of Hong Kong, Hong Kong, China (H.H.F.L.); Sarah Cannon Research Institute, Nashville (M.J.); University of California, San Francisco-Helen Diller Family Comprehensive Cancer Center, San Francisco (C.E.M.), University of California, San Diego, Moores Cancer Center, La Jolla (L.B.), and City of Hope Comprehensive Cancer Center, Duarte (K.L.R.) - all in California; University of Bern, Bern, and Cantonal Hospital of Lucerne, Lucerne - both in Switzerland (O.G.); Institut Gustave Roussy, Villejuif (B.B.), Hospital La Timone, Marseille (F.B.), and Centre Léon Bérard, Lyon (P.A.C.) - all in France; Severance Hospital, Yonsei University Health System (B.C.C.), and Samsung Medical Center, Sungkyunkwan University School of Medicine (K.P.), Seoul, and Seoul National University Bundang Hospital, Seongnam (Y.J.K.) - all in South Korea; Soroka University Medical Center, Beer-Sheva, Israel (N.P.); University of North Carolina-Chapel Hill, Chapel Hill (J. Weiss); National Cancer Center Hospital (Y.O.) and Cancer Institute Hospital of the Japanese Foundation for Cancer Research (M. Nishio), Tokyo, National Hospital Organization Kyushu Cancer Center, Fukuoka (T. Seto), Tottori University Hospital, Tottori (T. Sakamoto), Hyogo Cancer Center, Akashi (M.S.), Okayama University Hospital, Okayama (K.O.), and National Cancer Center Hospital East, Chiba (K.G.) - all in Japan; University of Chicago, Chicago (J.P.); the Ohio State University Comprehensive Cancer Center, Columbus (M.H.S.), and Cleveland Clinic, Cleveland (N.A.P.); Istituto Nazionale Tumori-National Cancer Institute, Università degli Studi di Milano, Milan (F.D.B.); Vall d'Hebron Institute of Oncology, Hospital Universitario Vall d'Hebron, Barcelona (E.G.); Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany (J. Wolf); Peter MacCallum Cancer Institute, Melbourne, VIC, Australia (B.S.); Sarah Cannon Research Institute at HealthONE, Denver (G.F.); Loxo Oncology, Stamford, CT (K.E., M. Nguyen, B.N., E.Y.Z., L.Y., X.H., E.O., S.M.R.); and the University of Texas M.D. Anderson Cancer Center, Houston (V.S.).

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http://dx.doi.org/10.1056/NEJMoa2005653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506467PMC
August 2020

The Effect of Food or Omeprazole on the Pharmacokinetics of Osimertinib in Patients With Non-Small-Cell Lung Cancer and in Healthy Volunteers.

J Clin Pharmacol 2018 04 26;58(4):474-484. Epub 2017 Nov 26.

Northern Centre for Cancer Care, Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/jcph.1035DOI Listing
April 2018

[DNA repair as a therapeutic target].

Bull Cancer 2017 Nov 11;104(11):988-998. Epub 2017 Nov 11.

Centre Léon-Bérard, département de médecine, 28, rue Laennec, 69008 Lyon, France.

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http://dx.doi.org/10.1016/j.bulcan.2017.09.005DOI Listing
November 2017

Targeting apoptosis in acute myeloid leukaemia.

Br J Cancer 2017 Oct 24;117(8):1089-1098. Epub 2017 Aug 24.

Department of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.

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http://dx.doi.org/10.1038/bjc.2017.281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674101PMC
October 2017

External Beam Radiation Therapy for Resectable Soft Tissue Sarcoma: A Systematic Review and Meta-Analysis.

Ann Surg Oncol 2018 Mar 11;25(3):754-767. Epub 2017 Sep 11.

Department of General, Visceral and Transplantation Surgery, Ludwig Maximilian University Hospital, Marchioninistr. 15, 81377, Munich, Germany.

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http://dx.doi.org/10.1245/s10434-017-6081-2DOI Listing
March 2018

Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study.

J Clin Oncol 2017 Jan 21;35(2):157-165. Epub 2016 Nov 21.

Lucia Nogova, Reinhard Buettner, and Jürgen Wolf, University Hospital Cologne, Cologne; Martin Schuler, University Hospital Essen, and German Cancer Consortium (DKTK), Essen, Germany; Lecia V. Sequist, Massachusetts General Hospital; Geoffrey I. Shapiro, Dana-Farber Cancer Institute, Boston, MA; Jose Manuel Perez Garcia, Vall d'Hebron Institut d'Oncologia, Barcelona; Manuel Hidalgo, Spanish National Cancer Research Centre, Madrid, Spain; Fabrice Andre, Gustave Roussy, Villejuif; Jean-Pierre Delord, Institute Universitaire du Cancer de Toulouse, Toulouse; Philippe A. Cassier, Centre Regional Leon-Berard, Lyon; Mario Campone, Institute de Cancerologie de l'Ouest-René Gauducheau, Nantes, France; Jan H.M. Schellens, Netherlands Cancer Institute, Amsterdam, and Utrecht University, Utrecht, the Netherlands; D. Ross Camidge, University of Colorado, Aurora, CO; Ulka Vaishampayan, Barbara Ann Karmanos Cancer Institute, Detroit, MI; Howard Burris, Sarah Cannon Research Institute, Nashville; G. Gary Tian, The West Clinic, Memphis, TN; Zev A. Wainberg, UCLA School of Medicine, Los Angeles, CA; Wan-Teck Lim, National Cancer Centre, Singapore; Patricia LoRusso, Yale Cancer Center, New Haven, CT; Katie Parker, Xueying Chen, Somesh Choudhury, and Randi Isaacs, Novartis Pharmaceuticals Corporation, East Hanover, NJ; Dale Porter, Novartis Institutes for Biomedical Research, Cambridge, MA; Francois Ringeisen, Novartis Pharma AG; and Diana Graus-Porta, Novartis Institutes for Biomedical Research, Basel, Switzerland.

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http://dx.doi.org/10.1200/JCO.2016.67.2048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865065PMC
January 2017

Current Systemic Treatment Options for Tenosynovial Giant Cell Tumor/Pigmented Villonodular Synovitis: Targeting the CSF1/CSF1R Axis.

Curr Treat Options Oncol 2016 Feb;17(2):10

Department of Medical Oncology, Centre Léon Bérard, 28 rue Laennec, Lyon, 69008, France.

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http://dx.doi.org/10.1007/s11864-015-0385-xDOI Listing
February 2016

Paclitaxel Given Once Per Week With or Without Bevacizumab in Patients With Advanced Angiosarcoma: A Randomized Phase II Trial.

J Clin Oncol 2015 Sep 27;33(25):2797-802. Epub 2015 Jul 27.

Isabelle L. Ray-Coquard, Philippe A. Cassier, and Jean-Yves Blay, Centre Léon Bérard and Claude Bernard University, Lyon; Julien Domont, Olivier Mir, and Axel Le Cesne, Gustave Roussy, Villejuif; Emmanuelle Tresch-Bruneel and Stéphanie Clisant, Centre Oscar Lambret; Nicolas Penel, Centre Oscar Lambret and Lille-Nord-de-France Medical School, Lille; Emmanuelle Bompas, Centre René Gauducheau, Nantes; Sophie Piperno-Neumann, Institut Curie, Paris; Antoine Italiano, Institut Bergonié, Bordeaux; Christine Chevreau, Institut Claudius Regaud, Toulouse; Didier Cupissol, Institut de Cancérologie de Montpellier, Val d'Aurelle, Montpellier; François Bertucci, Institut Paoli Calmette, Marseille; Jacques-Olivier Bay, Centre Jean Perrin, Clermont-Ferrand; Olivier Collard, Institut de Cancérologie de la Loire Lucien Neuwirth, Saint Priest en Jarez; Esma Saada-Bouzid, Centre Antoine Lacassagne, Nice; Nicolas Isambert, Centre Georges-François Leclerc, Dijon; and Corinne Delcambre, Centre François Baclesse, Caen, France.

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http://dx.doi.org/10.1200/JCO.2015.60.8505DOI Listing
September 2015

Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death.

EMBO Mol Med 2013 Dec 8;5(12):1821-34. Epub 2013 Oct 8.

Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, Lyon, France.

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http://embomolmed.embopress.org/cgi/doi/10.1002/emmm.2013026
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http://dx.doi.org/10.1002/emmm.201302654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914534PMC
December 2013

Emerging therapies for soft-tissue sarcomas.

Hematol Oncol Clin North Am 2013 Oct;27(5):1063-78

Department of Medical Oncology, Léon Bérard Cancer Center, 28 rue Laennec, Lyon 69008, France.

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http://dx.doi.org/10.1016/j.hoc.2013.07.011DOI Listing
October 2013

Outcome of patients with advanced solitary fibrous tumors: the Centre Léon Bérard experience.

BMC Cancer 2013 Mar 11;13:109. Epub 2013 Mar 11.

Department of Medical Oncology, Centre Léon Bérard, 28 rue Laennec, 69008, Lyon, France.

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http://dx.doi.org/10.1186/1471-2407-13-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623626PMC
March 2013

Gastrointestinal stromal tumors (GIST): a rare entity, a tumor model for personalized therapy, and yet ten different molecular subtypes.

Discov Med 2012 May;13(72):357-67

Department of Medicine, Centre Leon Berard, Lyon 69008, France.

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May 2012

Parallel anticancer drug development and molecular stratification to qualify predictive biomarkers: dealing with obstacles hindering progress.

Cancer Discov 2011 Aug;1(3):207-12

Drug Development Unit, The Royal Marsden National Health Service Foundation Trust, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0161DOI Listing
August 2011

Life-expectancy of patients enrolled in phase 1 clinical trials: a systematic review of published prognostic models.

Crit Rev Oncol Hematol 2012 Aug 9;83(2):242-8. Epub 2012 Jan 9.

Lille-Nord de France University (Equipe d'accueil 2694: Epidémiologie et Qualité des Soins), Lille, France.

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http://dx.doi.org/10.1016/j.critrevonc.2011.11.008DOI Listing
August 2012

Soft tissue sarcomas: are all soft tissue sarcomas treated with the same drugs?

Eur J Cancer 2011 Sep;47 Suppl 3:S385-8

Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1016/S0959-8049(11)70213-1DOI Listing
September 2011

Gastrointestinal stromal tumors of the stomach and duodenum.

Curr Opin Gastroenterol 2011 Oct;27(6):571-5

Departement de Médecine, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1097/MOG.0b013e32834bb7f0DOI Listing
October 2011

Therapeutic pipeline for soft-tissue sarcoma.

Expert Opin Pharmacother 2011 Nov 13;12(16):2479-91. Epub 2011 Sep 13.

Département de Médecine, Centre Léon Bérard, 69008 Lyon, France.

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http://dx.doi.org/10.1517/14656566.2011.604633DOI Listing
November 2011

Evaluation of the combination 5-fluorouracil, dacarbazine, and epirubicin in patients with advanced well-differentiated neuroendocrine tumors.

Clin Colorectal Cancer 2010 Oct;9(4):248-54

Hospices Civils de Lyon, Hôpital Edouard Herriot, Fédération des Spécialités Digestives, Lyon, France.

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http://dx.doi.org/10.3816/CCC.2010.n.037DOI Listing
October 2010

Imatinib mesylate for the treatment of gastrointestinal stromal tumor.

Expert Rev Anticancer Ther 2010 May;10(5):623-34

Centre Léon Bérard, 28 rue Laennec, 69008 Lyon, France.

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http://www.tandfonline.com/doi/full/10.1586/era.10.33
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http://dx.doi.org/10.1586/era.10.33DOI Listing
May 2010

Outcome of patients receiving chemotherapy for advanced biliary tract or gallbladder carcinoma.

Eur J Gastroenterol Hepatol 2010 Sep;22(9):1111-7

Department of Medical Oncology, Hopital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.

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http://dx.doi.org/10.1097/MEG.0b013e3283396ddeDOI Listing
September 2010

Molecular response prediction in gastrointestinal stromal tumors.

Target Oncol 2010 Mar 2;5(1):29-37. Epub 2010 Apr 2.

Département de Médecine, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.1007/s11523-010-0134-9DOI Listing
March 2010

Is there a role for discontinuing imatinib in patients with advanced gastrointestinal stromal tumour?

Curr Opin Oncol 2009 Jul;21(4):360-6

Département de Médecine & Unité INSERM U590, Centre Léon Bérard, Lyon, France.

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https://insights.ovid.com/crossref?an=00001622-200907000-000
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http://dx.doi.org/10.1097/CCO.0b013e32832c95f8DOI Listing
July 2009

Trabectedin for the management of soft-tissue sarcoma.

Expert Rev Anticancer Ther 2009 Jun;9(6):727-37

Unité de Jour d'Oncologie Médicale Multidisciplinaire, Hôpital Edouard Herriot, Lyon, France.

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http://dx.doi.org/10.1586/era.09.28DOI Listing
June 2009

Novel approaches to gastrointestinal stromal tumors resistant to imatinib and sunitinib.

Curr Gastroenterol Rep 2008 Dec;10(6):555-61

Conticanet Network of Excellence (LSH-060188), Département de Medicine, Centre Léon Bérard, 28 Rue Laennec, 69008 Lyon, France.

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http://dx.doi.org/10.1007/s11894-008-0102-zDOI Listing
December 2008

[Targeted therapy of sarcomas].

Bull Cancer 2008 Oct;95(10):963-74

Hôpital Edouard-Herriot, Service d'oncologie médicale, Lyon, France.

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http://dx.doi.org/10.1684/bdc.2008.0730DOI Listing
October 2008

Trabectedin and its potential in the treatment of soft tissue sarcoma.

Ther Clin Risk Manag 2008 Feb;4(1):109-16

Unité de Jour d'Oncologie Médicale Multidisciplinaire, Hôpital Edouard Herriot Lyon, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503645PMC
http://dx.doi.org/10.2147/tcrm.s1174DOI Listing
February 2008

Imatinib mesilate for the treatment of gastrointestinal stromal tumour.

Expert Opin Pharmacother 2008 May;9(7):1211-22

Unité de Jour d'Oncologie Médicale Multidisciplinaire, Pavillon E, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003, Lyon, France.

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http://dx.doi.org/10.1517/14656566.9.7.1211DOI Listing
May 2008

Mifepristone for ectopic ACTH secretion in metastatic endocrine carcinomas: report of two cases.

Eur J Endocrinol 2008 Jun 7;158(6):935-8. Epub 2008 Apr 7.

Unité de Jour d'Oncologie Médicale Multidisciplinaire, Hôpital Edouard Herriot, Lyon, France.

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http://dx.doi.org/10.1530/EJE-07-0792DOI Listing
June 2008

Emerging drugs for the treatment of soft tissue sarcomas.

Expert Opin Emerg Drugs 2007 Mar;12(1):139-53

Unité de Jour Oncologie Médicale Multidisciplinaire, Hopital Edouard Herriot, Lyon, France.

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http://dx.doi.org/10.1517/14728214.12.1.139DOI Listing
March 2007