Philipp Khaitovich

Philipp Khaitovich

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Philipp Khaitovich

Publications by authors named "Philipp Khaitovich"

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Hydrogen/Deuterium Exchange Aiding Compound Identification for LC-MS and MALDI Imaging Lipidomics.

Anal Chem 2019 Oct 8. Epub 2019 Oct 8.

Skolkovo Institute of Science and Technology , Novaya Street, 100 , Skolkovo 143025 , Russian Federation.

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http://dx.doi.org/10.1021/acs.analchem.9b02461DOI Listing
October 2019

Identification and Application of Gene Expression Signatures Associated with Lifespan Extension.

Cell Metab 2019 Sep 25;30(3):573-593.e8. Epub 2019 Jul 25.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.06.018DOI Listing
September 2019

Molecular footprint of Medawar's mutation accumulation process in mammalian aging.

Aging Cell 2019 Aug 6;18(4):e12965. Epub 2019 May 6.

Department of Biological Sciences, Middle East Technical University, Ankara, Turkey.

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http://dx.doi.org/10.1111/acel.12965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612638PMC
August 2019

"Redox lipidomics technology: Looking for a needle in a haystack".

Chem Phys Lipids 2019 Jul 27;221:93-107. Epub 2019 Mar 27.

Department of Environmental and Occupational Health, Pittsburgh, PA, USA; Pharmacology and Chemical Biology, Pittsburgh, PA, USA; Radiation Oncology, Pittsburgh, PA, USA; Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA; Laboratory of Navigational Redox Lipidomics, IM Sechenov Moscow State Medical University, Moscow, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2019.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714565PMC
July 2019

Lipidome Evolution in Mammalian Tissues.

Mol Biol Evol 2018 08;35(8):1947-1957

Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia.

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http://dx.doi.org/10.1093/molbev/msy097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063302PMC
August 2018

Human-specific features of spatial gene expression and regulation in eight brain regions.

Genome Res 2018 08 13;28(8):1097-1110. Epub 2018 Jun 13.

Cognitive Genomics Research Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Okazaki, Aichi 4448585, Japan.

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http://dx.doi.org/10.1101/gr.231357.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071643PMC
August 2018

Conservation, evolution, and regulation of splicing during prefrontal cortex development in humans, chimpanzees, and macaques.

RNA 2018 04 23;24(4):585-596. Epub 2018 Jan 23.

Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow 143028, Russia.

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http://dx.doi.org/10.1261/rna.064931.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855957PMC
April 2018

Predominant patterns of splicing evolution on human, chimpanzee and macaque evolutionary lineages.

Hum Mol Genet 2018 04;27(8):1474-1485

Skolkovo Institute of Science and Technology, 143025 Skolkovo, Russia.

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http://dx.doi.org/10.1093/hmg/ddy058DOI Listing
April 2018

Changes in Lipidome Composition during Brain Development in Humans, Chimpanzees, and Macaque Monkeys.

Mol Biol Evol 2017 05;34(5):1155-1166

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, CAS, Shanghai, China.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msx065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400384PMC
May 2017

Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder.

J Psychiatr Res 2016 May 8;76:74-83. Epub 2016 Feb 8.

Max Planck Institute of Psychiatry, Department of Translational Research in Psychiatry, Kraepelinstrasse 2-10, 80804 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2016.02.003DOI Listing
May 2016

Fluoxetine Treatment Rescues Energy Metabolism Pathway Alterations in a Posttraumatic Stress Disorder Mouse Model.

Mol Neuropsychiatry 2016 May 30;2(1):46-59. Epub 2016 Apr 30.

Departments of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany; Graduate School of Systemic Neurosciences, Ludwig Maximilians University Munich, Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1159/000445377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996011PMC
May 2016

Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain.

Genome Biol Evol 2016 Mar 23;8(3):840-50. Epub 2016 Mar 23.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai, China Skolkovo Institute for Science and Technology, Skolkovo, Russia Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany School of Life Science and Technology, ShanghaiTech University, Shanghai, China

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http://dx.doi.org/10.1093/gbe/evw038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824147PMC
March 2016

Evaluating intra- and inter-individual variation in the human placental transcriptome.

Genome Biol 2015 Mar 19;16:54. Epub 2015 Mar 19.

Max-Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, 04103, Germany.

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http://dx.doi.org/10.1186/s13059-015-0627-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404591PMC
March 2015

Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues.

Neuron 2015 Feb 5;85(4):695-702. Epub 2015 Feb 5.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai 200031, China; Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany; Skoltech Center for Computational and Systems Biology, Skolkovo Institute for Science and Technology, Skolkovo 143025, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.01.003DOI Listing
February 2015

De novo identification and quantification of single amino-acid variants in human brain.

J Mol Cell Biol 2014 Oct 9;6(5):421-33. Epub 2014 Jul 9.

Key Laboratory of Systems Biology, Chinese Academy of Sciences, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Shanghai 200031, China

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http://dx.doi.org/10.1093/jmcb/mju031DOI Listing
October 2014

Evolution of human longevity uncoupled from caloric restriction mechanisms.

PLoS One 2014 6;9(1):e84117. Epub 2014 Jan 6.

CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China ; Max Planck Institutes for Evolutionary Anthropology, Leipzig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084117PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882206PMC
September 2014

Conserved expression of lincRNA during human and macaque prefrontal cortex development and maturation.

RNA 2014 Jul 20;20(7):1103-11. Epub 2014 May 20.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai 200031, China Max Planck Institute for Evolutionary Anthropology, 04103 Leipzig, Germany.

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http://rnajournal.cshlp.org/cgi/doi/10.1261/rna.043075.113
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http://dx.doi.org/10.1261/rna.043075.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074677PMC
July 2014

Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes.

BMC Genomics 2014 Jun 10;15:457. Epub 2014 Jun 10.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, 200031 Shanghai, China.

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http://dx.doi.org/10.1186/1471-2164-15-457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094773PMC
June 2014

Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness.

PLoS Biol 2014 May 27;12(5):e1001871. Epub 2014 May 27.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai, China; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pbio.1001871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035273PMC
May 2014

Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans.

Nat Commun 2014 Apr 1;5:3584. Epub 2014 Apr 1.

1] CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai 200031, China [2] Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.

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http://www.nature.com/articles/ncomms4584
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http://dx.doi.org/10.1038/ncomms4584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988804PMC
April 2014

Widespread splicing changes in human brain development and aging.

Mol Syst Biol 2013 ;9:633

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/msb.2012.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564255PMC
September 2013

Evolution of the human-specific microRNA miR-941.

Nat Commun 2012 ;3:1145

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1038/ncomms2146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493648PMC
June 2013

Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content.

PLoS One 2012 24;7(8):e43915. Epub 2012 Aug 24.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043915PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427207PMC
February 2013

Human brain evolution: transcripts, metabolites and their regulators.

Nat Rev Neurosci 2013 Feb 17;14(2):112-27. Epub 2013 Jan 17.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai, 200031, China.

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http://dx.doi.org/10.1038/nrn3372DOI Listing
February 2013

Stress-associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain.

Aging Cell 2012 Dec 18;11(6):1055-64. Epub 2012 Oct 18.

Chinese Academy of Sciences Key laboratory for Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai, 200031, China.

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http://dx.doi.org/10.1111/acel.12007DOI Listing
December 2012

Accelerated aging-related transcriptome changes in the female prefrontal cortex.

Aging Cell 2012 Oct 2;11(5):894-901. Epub 2012 Aug 2.

Key Laboratory for Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1111/j.1474-9726.2012.00859.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470704PMC
October 2012

Spatial proximity and similarity of the epigenetic state of genome domains.

PLoS One 2012 4;7(4):e33947. Epub 2012 Apr 4.

Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033947PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319547PMC
August 2012

Layer cake: the first bite at gene expression diversity in the human brain.

Genome Biol 2012 May 22;13(5):157. Epub 2012 May 22.

CAS-MPG Partner Institute for Computational Biology, Yue Yang road 320, Shanghai, 200031, China.

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http://dx.doi.org/10.1186/gb-2012-13-5-157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446282PMC
May 2012

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques.

Genome Res 2012 Apr 2;22(4):611-22. Epub 2012 Feb 2.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, 200031 Shanghai, China.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.127324.111
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http://dx.doi.org/10.1101/gr.127324.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317144PMC
April 2012

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.

PLoS Biol 2011 Dec 6;9(12):e1001214. Epub 2011 Dec 6.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1371/journal.pbio.1001214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232219PMC
December 2011

MicroRNA expression and regulation in human, chimpanzee, and macaque brains.

PLoS Genet 2011 Oct 13;7(10):e1002327. Epub 2011 Oct 13.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1371/journal.pgen.1002327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192836PMC
October 2011

Widespread expression of piRNA-like molecules in somatic tissues.

Nucleic Acids Res 2011 Aug 5;39(15):6596-607. Epub 2011 May 5.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, 320 Yueyang Road, 200031, Shanghai, China.

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http://dx.doi.org/10.1093/nar/gkr298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159465PMC
August 2011

Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway.

Cell Metab 2011 Aug;14(2):161-72

Chinese Academy of Sciences Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, China.

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http://dx.doi.org/10.1016/j.cmet.2011.07.001DOI Listing
August 2011

Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series.

BMC Bioinformatics 2011 Aug 18;12:347. Epub 2011 Aug 18.

Key Laboratory for Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1186/1471-2105-12-347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180390PMC
August 2011

Rapid metabolic evolution in human prefrontal cortex.

Proc Natl Acad Sci U S A 2011 Apr 28;108(15):6181-6. Epub 2011 Mar 28.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, 200031 Shanghai, China.

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http://dx.doi.org/10.1073/pnas.1019164108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076848PMC
April 2011

Ab initio identification of transcription start sites in the Rhesus macaque genome by histone modification and RNA-Seq.

Nucleic Acids Res 2011 Mar 14;39(4):1408-18. Epub 2010 Oct 14.

Chinese Academy of Sciences Key Laboratory of Molecular Developmental Biology, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Lincui East Road, Beijing, 100101, Chinese.

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http://dx.doi.org/10.1093/nar/gkq956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045608PMC
March 2011

Annotating conserved and novel features of primate transcriptomes using sequencing.

Genome Biol 2010 23;11(7):125. Epub 2010 Jul 23.

Partner Institute for Computational Biology, Chinese Academy of Sciences, 320 Yue Yang Road, 200031 Shanghai, China.

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http://dx.doi.org/10.1186/gb-2010-11-7-125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926776PMC
December 2010

Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel.

Physiol Genomics 2010 Sep 4;42A(1):39-51. Epub 2010 May 4.

CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes of Biological Sciences, Shanghai, China.

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http://dx.doi.org/10.1152/physiolgenomics.00054.2010DOI Listing
September 2010

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain.

Genome Res 2010 Sep 20;20(9):1207-18. Epub 2010 Jul 20.

Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1101/gr.106849.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928499PMC
September 2010

Comprehensive survey of human brain microRNA by deep sequencing.

BMC Genomics 2010 Jun 30;11:409. Epub 2010 Jun 30.

Partner Institute for Computational Biology, 320 Yueyang Road, 200031 Shanghai, China.

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http://dx.doi.org/10.1186/1471-2164-11-409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996937PMC
June 2010

The effects of probe binding affinity differences on gene expression measurements and how to deal with them.

Bioinformatics 2009 Nov 18;25(21):2772-9. Epub 2009 Aug 18.

Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btp492DOI Listing
November 2009

Evidence for human microRNA-offset RNAs in small RNA sequencing data.

Bioinformatics 2009 Sep 6;25(18):2298-301. Epub 2009 Jul 6.

Department of Computer Science, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btp419DOI Listing
September 2009

Sequence features associated with microRNA strand selection in humans and flies.

BMC Genomics 2009 Sep 4;10:413. Epub 2009 Sep 4.

Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai, 200031, PR China.

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http://dx.doi.org/10.1186/1471-2164-10-413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751786PMC
September 2009

Fast mapping of short sequences with mismatches, insertions and deletions using index structures.

PLoS Comput Biol 2009 Sep 11;5(9):e1000502. Epub 2009 Sep 11.

Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1000502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730575PMC
September 2009

Transcriptional neoteny in the human brain.

Proc Natl Acad Sci U S A 2009 Apr 23;106(14):5743-8. Epub 2009 Mar 23.

Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.

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http://dx.doi.org/10.1073/pnas.0900544106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659716PMC
April 2009

Estimating accuracy of RNA-Seq and microarrays with proteomics.

BMC Genomics 2009 Apr 16;10:161. Epub 2009 Apr 16.

Key lab of Systems Biology, Shanghai Institutes for Biological Sciences, China Academy of Sciences, Shanghai, 200031, PR China.

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http://dx.doi.org/10.1186/1471-2164-10-161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676304PMC
April 2009

Metabolic changes in schizophrenia and human brain evolution.

Genome Biol 2008 5;9(8):R124. Epub 2008 Aug 5.

Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Yue Yang Road, Shanghai, 200031, PR China.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2008-9-8-r124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575514PMC
December 2008

Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.

Am J Hum Genet 2008 Aug 24;83(2):208-18. Epub 2008 Jul 24.

Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Rue Michel-Servet 1, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.ajhg.2008.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495069PMC
August 2008

Brain expression--is it all in our SNPs?

Mol Syst Biol 2007 18;3:155. Epub 2007 Dec 18.

Department of Comparative Biology, Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/msb4100199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174631PMC
January 2008

Human and chimpanzee gene expression differences replicated in mice fed different diets.

PLoS One 2008 Jan 30;3(1):e1504. Epub 2008 Jan 30.

Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001504PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200793PMC
January 2008

Human brain evolution.

Prog Brain Res 2006 ;158:295-309

Max-Planck Institute for Evolutionary Anthropology, Deutscher Platz, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/S0079-6123(06)58014-8DOI Listing
February 2007

FUNC: a package for detecting significant associations between gene sets and ontological annotations.

BMC Bioinformatics 2007 Feb 6;8:41. Epub 2007 Feb 6.

Max-Planck-Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/1471-2105-8-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800870PMC
February 2007

Comparison of protein and mRNA expression evolution in humans and chimpanzees.

PLoS One 2007 Feb 14;2(2):e216. Epub 2007 Feb 14.

Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000216PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1789144PMC
February 2007

Evolution of primate gene expression.

Nat Rev Genet 2006 Sep;7(9):693-702

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1038/nrg1940DOI Listing
September 2006

Systematic analysis of gene expression in human brains before and after death.

Genome Biol 2005 30;6(13):R112. Epub 2005 Dec 30.

Max-Planck-Institute for Evolutionary Anthropology, Deutscher Platz, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/gb-2005-6-13-r112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414111PMC
July 2006

Functional analysis of human and chimpanzee promoters.

Genome Biol 2005 1;6(7):R57. Epub 2005 Jul 1.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/gb-2005-6-7-r57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175988PMC
June 2006

Aging and gene expression in the primate brain.

PLoS Biol 2005 Sep 2;3(9):e274. Epub 2005 Aug 2.

Department of Molecular and Cell Biology, University of California, Berkeley, California, USA.

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http://dx.doi.org/10.1371/journal.pbio.0030274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1181540PMC
September 2005

A genome-wide comparison of recent chimpanzee and human segmental duplications.

Nature 2005 Sep;437(7055):88-93

Howard Hughes Medical Institute, Department of Genome Sciences, University of Washington School of Medicine, 1705 NE Pacific Street, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1038/nature04000DOI Listing
September 2005

Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

Science 2005 Sep 1;309(5742):1850-4. Epub 2005 Sep 1.

Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103 Leipzig, Germany.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1108296
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September 2005

Toward a neutral evolutionary model of gene expression.

Genetics 2005 Jun 16;170(2):929-39. Epub 2005 Apr 16.

Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://www.genetics.org/lookup/doi/10.1534/genetics.104.0371
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http://dx.doi.org/10.1534/genetics.104.037135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450413PMC
June 2005

A neutral model of transcriptome evolution.

PLoS Biol 2004 May 11;2(5):E132. Epub 2004 May 11.

Max-Planck-Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pbio.0020132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC406393PMC
May 2004