Philipp J Jost

Philipp J Jost

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Philipp J Jost

Philipp J Jost

Publications by authors named "Philipp J Jost"

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Durable remissions with venetoclax monotherapy in secondary AML refractory to hypomethylating agents and high expression of BCL-2 and/or BIM.

Eur J Haematol 2019 May 28;102(5):437-441. Epub 2019 Feb 28.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Cancer Cluster Salzburg, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1111/ejh.13218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849823PMC
May 2019

XIAP deficiency in hematopoietic recipient cells drives donor T-cell activation and GvHD in mice.

Eur J Immunol 2019 Mar 3;49(3):504-507. Epub 2019 Jan 3.

Medizinische Klinik III, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1002/eji.201847818DOI Listing
March 2019

Necroinflammation emerges as a key regulator of hematopoiesis in health and disease.

Cell Death Differ 2019 01 21;26(1):53-67. Epub 2018 Sep 21.

Medical Department III of Hematology and Oncology, Klinikum Rechts der Isar, Technische Universität München, 81675, München, Germany.

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http://dx.doi.org/10.1038/s41418-018-0194-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294770PMC
January 2019

Eculizumab as salvage therapy for recurrent monoclonal gammopathy-induced C3 glomerulopathy in a kidney allograft.

BMC Nephrol 2018 05 3;19(1):106. Epub 2018 May 3.

Department of Nephropathology, Institute of Pathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1186/s12882-018-0904-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934889PMC
May 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.

Cell Rep 2017 07;20(3):668-682

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.06.073DOI Listing
July 2017

Killing AML: RIPK3 leads the way.

Cell Cycle 2017 01 11;16(1):3-4. Epub 2016 Oct 11.

a III. Medizinische Klinik für Hämatologie und Internistische Onkologie, Klinikum rechts der Isar, Technische Universität München , Munich , Germany.

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http://dx.doi.org/10.1080/15384101.2016.1232069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270541PMC
January 2017

Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.

Cell Death Dis 2016 10 13;7(10):e2422. Epub 2016 Oct 13.

Institute of Pharmacology, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1038/cddis.2016.311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133978PMC
October 2016

RIPK3-dependent cell death and inflammasome activation in FLT3-ITD expressing LICs.

Oncotarget 2016 09;7(36):57483-57484

Medizinische Klinik für Hämatologie und Internistische Onkologie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.18632/oncotarget.11195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295366PMC
September 2016

RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.

Cancer Cell 2016 07;30(1):75-91

III. Medical Department for Hematology and Oncology, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.06.002DOI Listing
July 2016

XIAP as a regulator of inflammatory cell death: the TNF and RIP3 angle.

Mol Cell Oncol 2015 Jan-Mar;2(1):e964622. Epub 2014 Oct 29.

III. Medizinische Klink; Klinikum rechts der Isar; Technische Universität München ; Germany.

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http://dx.doi.org/10.4161/23723548.2014.964622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905225PMC
June 2016

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.

Cell Rep 2016 Mar 17;14(12):2846-58. Epub 2016 Mar 17.

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819907PMC
March 2016

XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.

Cell Rep 2014 Jun 29;7(6):1796-808. Epub 2014 May 29.

III. Medizinische Klink, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.05.008DOI Listing
June 2014

The acute transcriptomic and proteomic response of HC-04 hepatoma cells to hepatocyte growth factor and its implications for Plasmodium falciparum sporozoite invasion.

Mol Cell Proteomics 2014 May 16;13(5):1153-64. Epub 2014 Feb 16.

W. Harry Feinstone Department of Molecular Microbiology & Immunology and the Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA;

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http://dx.doi.org/10.1074/mcp.M113.035584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014276PMC
May 2014

Local cooling reduces regional bone blood flow.

J Orthop Res 2013 Nov 28;31(11):1820-7. Epub 2013 Jun 28.

Department of Trauma Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Straße 22, 81675, Munich, Germany; Department of Orthopaedic Sports Medicine, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Straße 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1002/jor.22417DOI Listing
November 2013

Evidence of an autoregulatory mechanism of regional bone blood flow at hypotension.

Arch Orthop Trauma Surg 2013 Sep 6;133(9):1233-41. Epub 2013 Jul 6.

Department of Orthopaedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Straße 22, Munich, Germany.

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http://dx.doi.org/10.1007/s00402-013-1801-yDOI Listing
September 2013

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.

EMBO Mol Med 2013 Aug 1;5(8):1278-95. Epub 2013 Jul 1.

Department of Disease Biology, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/emmm.201303090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944466PMC
August 2013

Mcl-1 is essential for germinal center formation and B cell memory.

Science 2010 Nov 7;330(6007):1095-9. Epub 2010 Oct 7.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1126/science.1191793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991396PMC
November 2010

XIAP discriminates between type I and type II FAS-induced apoptosis.

Nature 2009 Aug 22;460(7258):1035-9. Epub 2009 Jul 22.

The Walter and Eliza Hall Institute of Medical Research, Melbourne University, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1038/nature08229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956120PMC
August 2009

The many roles of FAS receptor signaling in the immune system.

Immunity 2009 Feb;30(2):180-92

The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1016/j.immuni.2009.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956119PMC
February 2009

Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications.

Blood 2007 Apr;109(7):2700-7

III Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1182/blood-2006-07-025809DOI Listing
April 2007

Bcl10/Malt1 signaling is essential for TCR-induced NF-kappaB activation in thymocytes but dispensable for positive or negative selection.

J Immunol 2007 Jan;178(2):953-60

Third Medical Department, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675 Munich, Germany.

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http://dx.doi.org/10.4049/jimmunol.178.2.953DOI Listing
January 2007