Philip Van Damme

Philip Van Damme

UNVERIFIED PROFILE

Are you Philip Van Damme?   Register this Author

Register author
Philip Van Damme

Philip Van Damme

Publications by authors named "Philip Van Damme"

Are you Philip Van Damme?   Register this Author

100Publications

5118Reads

47Profile Views

Inflammatory markers in cerebrospinal fluid: independent prognostic biomarkers in amyotrophic lateral sclerosis?

J Neurol Neurosurg Psychiatry 2019 Dec 7;90(12):1338-1346. Epub 2019 Jun 7.

Department of Neurosciences, Laboratory for Molecular Neurobiomarker Research, KU Leuven, Leuven, Belgium

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2018-319586DOI Listing
December 2019

Serum neurofilament heavy chains as early marker of motor neuron degeneration.

Ann Clin Transl Neurol 2019 Oct 13;6(10):1971-1979. Epub 2019 Sep 13.

Laboratory for Molecular Neurobiomarker Research, Department of Neurosciences, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/acn3.50890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801162PMC
October 2019

Reducing EphA4 before disease onset does not affect survival in a mouse model of Amyotrophic Lateral Sclerosis.

Sci Rep 2019 Oct 1;9(1):14112. Epub 2019 Oct 1.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-50615-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773754PMC
October 2019

C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport.

Sci Rep 2019 Oct 31;9(1):15728. Epub 2019 Oct 31.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-52035-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823349PMC
October 2019

Analytical performance of a CE-marked immunoassay to quantify phosphorylated neurofilament heavy chains.

Clin Chem Lab Med 2019 Jul;57(8):e199-e202

Department of Neurosciences, Laboratory for Molecular Neurobiomarker Research, KU Leuven (University of Leuven), Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/cclm-2018-1004DOI Listing
July 2019

Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model.

Acta Neuropathol Commun 2019 Jul 5;7(1):107. Epub 2019 Jul 5.

Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Herestraat 49, 3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-019-0750-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612190PMC
July 2019

Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis.

Acta Neuropathol Commun 2019 Jul 12;7(1):114. Epub 2019 Jul 12.

Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-019-0759-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626434PMC
July 2019

Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis.

Neurology 2019 Jun 22;92(23):e2661-e2673. Epub 2019 May 22.

From the Department of Neurology (J.F.H.), University of North Carolina, Chapel Hill; Krembil Neuroscience Centre (V.B.), University Health Network, Toronto, Canada; Department of Neurology (T.M.B.), University of Virginia, Charlottesville; Department of Neuroimmunology and Neuromuscular Diseases (R.M.), Fondazione Istituto Neurologico Carlo Besta, Milan, Italy; Department of Neurology (B.M.), Wroclaw Medical University; Department of Neurology (A.S.), Jagiellonian University Medical College, Cracow, Poland; Department of Neurology (S.B.), University of Southern California, Keck School of Medicine, Los Angeles County Medical Center; Department of Neurology (F.J.R.D.R.G.), La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Autonoma University of Madrid, Spain; Neuroimmunology Unit, Department Clinical Neuroscience (F.P.), Karolinska Institutet, Karolinska University Hospital (Solna), Stockholm, Sweden; USC Neurologia (M.R.), USS Malattie Autoimmuni-Centro Sclerosi Multipla, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy; Neurology Department (P.V.D.), University Hospitals Leuven; Laboratory of Neurobiology (P.V.D.), Department of Neuroscience, KU Leuven and Center for Brain & Disease Research, VIB, Leuven, Belgium; Department of Neurology (T.V.), University of South Florida, Morsani College of Medicine, Tampa; Institute of Neurology (A.E.), Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy; Neurology Department (M.F.), The Ohio State University, Columbus; Department of Neurology (T.M.), University of California, Irvine; Department of Molecular and Cellular Medicine (E.S.W.), Texas A&M University Health Science Center, College Station; argenx BVBA (T.D., P.U., K.V., A.G., H.d.H., N.L.), Zwijnaarde, Belgium; and Department of Neurology (J.J.G.M.V.), Leiden University Medical Center (LUMC), the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000007600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556100PMC
June 2019

An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology.

Acta Neuropathol 2019 May 27;137(5):855-858. Epub 2019 Mar 27.

Department of Neurosciences, Laboratory for Neuropathology, KU Leuven, Leuven Brain Institute (LBI), Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-019-01996-zDOI Listing
May 2019

Clinical spectrum of the anti-GQ1b antibody syndrome: a case series of eight patients.

Acta Neurol Belg 2019 Mar 12;119(1):29-36. Epub 2019 Feb 12.

Department of Neurology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13760-019-01093-8DOI Listing
March 2019

Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits.

J Neuroinflammation 2019 Mar 13;16(1):61. Epub 2019 Mar 13.

Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Cell Metabolism, KU Leuven - University of Leuven, Campus Gasthuisberg O/N2, Herestraat 49, B-3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12974-019-1442-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417251PMC
March 2019

Derivation of norms for the Dutch version of the Edinburgh cognitive and behavioral ALS screen.

Amyotroph Lateral Scler Frontotemporal Degener 2019 02 12;20(1-2):19-27. Epub 2018 Oct 12.

a Department of Neurology , Brain Centre Rudolf Magnus, University Medical Centre Utrecht , Utrecht , The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2018.1522352DOI Listing
February 2019

Detection of myositis-specific antibodies.

Ann Rheum Dis 2019 01 25;78(1):e7. Epub 2018 Jan 25.

Department of Microbiology and Immunology, Experimental Laboratory Immunology, KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2017-21291
Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2017-212915DOI Listing
January 2019

Diagnostic and Prognostic Performance of Neurofilaments in ALS.

Front Neurol 2018 18;9:1167. Epub 2019 Jan 18.

Laboratory of Neurobiology, Department of Neurosciences, KU Leuven and Center for Brain & Disease Research VIB Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fneur.2018.01167
Publisher Site
http://dx.doi.org/10.3389/fneur.2018.01167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345692PMC
January 2019

FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins.

Hum Mol Genet 2018 12;27(23):4103-4116

Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven-University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg
Publisher Site
http://dx.doi.org/10.1093/hmg/ddy303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240733PMC
December 2018

Glucose metabolic brain patterns to discriminate amyotrophic lateral sclerosis from Parkinson plus syndromes.

EJNMMI Res 2018 Dec 13;8(1):110. Epub 2018 Dec 13.

Department of Nuclear Medicine and Molecular Imaging, Division of Nuclear Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13550-018-0458-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292827PMC
December 2018

Multicenter validation of [F]-FDG PET and support-vector machine discriminant analysis in automatically classifying patients with amyotrophic lateral sclerosis versus controls.

Amyotroph Lateral Scler Frontotemporal Degener 2018 11 4;19(7-8):570-577. Epub 2018 Jun 4.

a Division of Nuclear Medicine and Department of Imaging and pathology , University Hospitals Leuven and KU Leuven , Leuven , Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/21678421.2018.1476548DOI Listing
November 2018

Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis.

Neurobiol Dis 2018 11 26;119:26-40. Epub 2018 Jul 26.

KU Leuven - University of Leuven, Department of Neurosciences, Laboratory of Neurobiology and Experimental Neurology, and Leuven Brain Institute (LBI), Herestraat 49, B-3000 Leuven, Belgium; VIB, Center for Brain & Disease Research, Herestraat 49, B-3000 Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Herestraat 49, B-3000 Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2018.07.012DOI Listing
November 2018

Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.

Alzheimers Dement 2018 10 20;14(10):1261-1280. Epub 2018 Jul 20.

Department of Development and Regeneration, Stem Cell Biology and Embryology, KU Leuven Stem Cell Institute, Leuven, Belgium; KU Leuven-Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.05.007DOI Listing
October 2018

Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice.

Mol Neurodegener 2018 10 16;13(1):55. Epub 2018 Oct 16.

Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
https://molecularneurodegeneration.biomedcentral.com/article
Publisher Site
http://dx.doi.org/10.1186/s13024-018-0288-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192075PMC
October 2018

How much of the missing heritability of ALS is hidden in known ALS genes?

Authors:
Philip Van Damme

J Neurol Neurosurg Psychiatry 2018 08 12;89(8):794. Epub 2018 Apr 12.

Department of Neuroscience, Experimental Neurology, University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2018-318354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204935PMC
August 2018

Conditional deletion of Id2 or Notch1 in oligodendrocyte progenitor cells does not ameliorate disease outcome in SOD1 mice.

Neurobiol Aging 2018 08 3;68:1-4. Epub 2018 Apr 3.

Department of Neurosciences, KU Leuven-University of Leuven, Experimental Neurology, Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium; Department of Neurology, University Hospitals Leuven, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01974580183011
Publisher Site
http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998381PMC
August 2018

From lexical regularities to axiomatic patterns for the quality assurance of biomedical terminologies and ontologies.

J Biomed Inform 2018 08 14;84:59-74. Epub 2018 Jun 14.

Departamento de Informática y Sistemas, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbi.2018.06.008DOI Listing
August 2018

Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity.

Cell Rep 2018 07;24(3):529-537.e4

Experimental Neurology, Department of Neurosciences, and Leuven Brain Institute (LBI), KU Leuven-University of Leuven, 3000 Leuven, Belgium; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, 3000 Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.06.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077250PMC
July 2018

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration.

J Vis Exp 2018 06 15(136). Epub 2018 Jun 15.

Department of Neurosciences, Experimental Neurology, KU Leuven - University of Leuven; Center for Brain & Disease Research, Laboratory of Neurobiology, VIB;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/57741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101751PMC
June 2018

Comparison of elevated phosphorylated neurofilament heavy chains in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2018 04 20;89(4):367-373. Epub 2017 Oct 20.

Department of Neurosciences, Laboratory for Molecular Neurobiomarker Research, KU Leuven (University of Leuven), Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2017-316605DOI Listing
April 2018

Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.

Neurobiol Dis 2018 03 29;111:59-69. Epub 2017 Nov 29.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbd.2017.11.011DOI Listing
March 2018

Anterior interosseous mononeuropathy associated with HEV infection.

Neurol Neuroimmunol Neuroinflamm 2018 Mar 22;5(2):e429. Epub 2017 Dec 22.

Department of Neurosciences, Experimental Neurology (B.S., S.B., P.V.D.), KU Leuven-University of Leuven; Laboratory of Neurobiology (B.S., S.B., P.V.D.), Center for Brain & Disease Research, VIB; Departments of Neurology (B.S., M.S., K.G.C., P.V.D.), and Laboratory Medicine (V.S.), University Hospitals Leuven; and Laboratory for Cognitive Neurology (M.S.), Department of Neurosciences, Department of Microbiology and Immunology (V.S.), Laboratory for Muscle Diseases and Neuropathies (K.G.C.), Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXI.0000000000000429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745356PMC
March 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients.

Neurobiol Aging 2018 01 31;61:255.e1-255.e7. Epub 2017 Aug 31.

Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2017.08.021DOI Listing
January 2018

Multicenter evaluation of neurofilaments in early symptom onset amyotrophic lateral sclerosis.

Neurology 2018 01 6;90(1):e22-e30. Epub 2017 Dec 6.

From the Nuffield Department of Clinical Neurosciences (E.F., E.G., M.R.T.), University of Oxford, UK; Department of Neurology (P.O., P.S., F.V., J.H.W., P.W., A.C.L., M.O.), Ulm University Hospital, Germany; Department of Pathophysiology and Transplantation (F.V., V.S.), Università degli Studi di Milano; Department of Neurology-Stroke Unit and Laboratory of Neuroscience (F.V., C.M., V.S.), IRCCS Istituto Auxologico Italiano, Milan, Italy; Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, and Biomedicine (C.B., J.K.), University Hospital and University of Basel, Switzerland; Department of Neurology (P.V.D.) and Laboratory of Molecular Neurobiomarker Research and Laboratory Medicine (K.P.), University Hospitals Leuven; KU Leuven-University of Leuven (P.V.D.); Department of Neurosciences (P.V.D.), VIB-Center for Brain & Disease Research, Leuven, Belgium; Department of Neurology (J.G., P.M., B.S.), Jena University Hospital, Germany; Department of Metabolic Biochemistry (C.J., F.L.) and Neurological Diseases Department (M.d.M.A., F.S.), Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris, France; Department of Neurology (S.K., S.P.), Hannover Medical School; Institute for Epidemiology and Medical Biometry (B.M.) Ulm University, Germany; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology (J.R., M.M.V.), and Radboud Alzheimer Center, Department of Laboratory Medicine (M.M.V.), Radboud University Medical Center, Nijmegen, the Netherlands; and Department of Neurodegenerative Disease and Gerontopsychiatry/Neurology (P.W.), Bonn University Hospital, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000004761DOI Listing
January 2018

Finger extension weakness and downbeat nystagmus motor neuron disease syndrome: A novel motor neuron disorder?

Muscle Nerve 2017 Dec 15;56(6):1164-1168. Epub 2017 May 15.

Department of Neurology, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.25669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656559PMC
December 2017

Defining Y-SNP variation among the Flemish population (Western Europe) by full genome sequencing.

Forensic Sci Int Genet 2017 11 28;31:e12-e16. Epub 2017 Oct 28.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), Leuven, Belgium; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fsigen.2017.10.008DOI Listing
November 2017

Is there a glucose metabolic signature of spreading TDP-43 pathology in Amyotrophic Lateral Sclerosis?

Q J Nucl Med Mol Imaging 2017 Nov 22. Epub 2017 Nov 22.

Division of Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospitals Leuven and KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23736/S1824-4785.17.03009-6DOI Listing
November 2017

Patient-ventilator asynchrony, leaks and sleep in patients with amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):343-50. Epub 2016 Apr 14.

a Department of Pulmonology and Leuven University Centre for Sleep and Wake disorders (LUCS) - University Hospitals Leuven .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/21678421.2016.1170149DOI Listing
October 2017

A mapping review of international guidance on the management and care of amyotrophic lateral sclerosis (ALS).

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):325-36. Epub 2016 Apr 14.

m Walter Sermeus, KU Leuven Institute for Healthcare Policy, Department of Public Health and Primary Care , University of Leuven - KU Leuven , Leuven , Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/21678421.2016.1167911DOI Listing
October 2017

Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access: An Editorial Comment for 'The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C' on page 236.

Authors:
Philip Van Damme

J Neurochem 2017 10 4;143(2):154-157. Epub 2017 Aug 4.

Department of Neurosciences, Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jnc.14125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655790PMC
October 2017

Randomized cross-over trial of ventilator modes during non-invasive ventilation titration in amyotrophic lateral sclerosis.

Respirology 2017 08 4;22(6):1212-1218. Epub 2017 Apr 4.

Department of Pulmonology and Leuven University Centre for Sleep and Wake Disorders (LUCS), University Hospitals Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.13046DOI Listing
August 2017

Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.

Hum Mol Genet 2017 08;26(15):2850-2863

Department of Neurosciences, Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, B-3000 Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddx162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886064PMC
August 2017

Identification and characterization of Nanobodies targeting the EphA4 receptor.

J Biol Chem 2017 07 19;292(27):11452-11465. Epub 2017 May 19.

From the KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), 3000 Leuven, Belgium,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M116.774141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500810PMC
July 2017

Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease.

Neurology 2017 Jun 12;88(24):2302-2309. Epub 2017 May 12.

From the Laboratory for Molecular Neurobiomarker Research (K.P., M.D.S., B.G.), Laboratory for Cognitive Neurology (R.V.) and Laboratory of Neurobiology (Center for Brain & Disease Research, VIB, Leuven) (P.V.D.), Department of Neurosciences, KU Leuven (University of Leuven); Laboratory Medicine (K.P., M.D.S.) and Department of Neurology (O.S., K.G.C., G.C., A.D., N.L., P.T., D.V.R., R.V., P.V.D.), University Hospitals Leuven, Belgium; Hans Berger Department of Neurology (B.S., T.P., T.M.R., N.F., B.H., M.R., A.R., A.G., O.W.W., J.G.) and Institute for Biochemistry (P.M., S.W., H.R.), Jena University Hospital, Germany; INSERM, U942 (S.G., C.P.), Groupe Hospitalier Lariboisière Fernand-Widal Saint-Louis, CMRR Paris Nord AP-HP, Université Paris Diderot, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000004029DOI Listing
June 2017

Modelling amyotrophic lateral sclerosis: progress and possibilities.

Dis Model Mech 2017 05;10(5):537-549

KU Leuven, University of Leuven, Department of Neurosciences, Experimental Neurology, and Leuven Research Institute for Neuroscience and Disease (LIND), B-3000 Leuven, Belgium

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dmm.029058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451175PMC
May 2017

Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease.

Neurotherapeutics 2017 04;14(2):417-428

KU Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), University of Leuven, B-3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13311-016-0501-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398982PMC
April 2017

Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks.

Eur J Nucl Med Mol Imaging 2017 Mar 8;44(3):533-547. Epub 2016 Dec 8.

Division of Nuclear Medicine, Department of Imaging and Pathology, University Hospitals Leuven and KU Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-016-3587-yDOI Listing
March 2017

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Hum Mutat 2017 03 19;38(3):297-309. Epub 2017 Jan 19.

Center for Molecular Neurology, VIB, Antwerp, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.23161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324646PMC
March 2017

Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients.

Neurobiol Aging 2017 03 21;51:177.e9-177.e16. Epub 2016 Dec 21.

Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2016.12.008DOI Listing
March 2017

Negative commercial screening test for paraneoplastic antibodies in a case of opsoclonus.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 3;4(2):e329. Epub 2017 Feb 3.

Department of Neurology (N.V., M.S., P.V.D.), Department of Ophthalmology (C.C.), and Laboratory Medicine (X.B., K.P.), University Hospital Leuven; Department of Microbiology and Immunology (X.B.), Experimental Laboratory Immunology, Leuven, Belgium; Department of Immunology (T.V.), St Eloi Hospital, Montpellier University, France; Department of Neurosciences (P.V.D.), Laboratory for Neurobiology; Vesalius Research Center (P.V.D.), Flemish Institute for Biotechnology (VIB); and Department of Neurosciences (B.G., K.P.), Laboratory for Molecular Neurobiomarker Research, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXI.0000000000000329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292927PMC
March 2017

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.

Mol Cell 2017 Mar;65(6):1044-1055.e5

Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Department of Neurosciences, KU Leuven - University of Leuven, 3000 Leuven, Belgium; Laboratory of Neurobiology, VIB, Center for Brain and Disease Research, 3000 Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2017.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364369PMC
March 2017

IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients.

J Autoimmun 2017 02 10;77:104-115. Epub 2016 Dec 10.

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2016.11.005DOI Listing
February 2017

Diagnostic Challenges and Clinical Characteristics of Hepatitis E Virus-Associated Guillain-Barré Syndrome.

JAMA Neurol 2017 Jan;74(1):26-33

Department of Neurology, University Hospitals Leuven, Leuven, Belgium2Department of Neurosciences, Experimental Neurology, KU Leuven, University of Leuven, Leuven, Belgium5VIB, Vesalius Research Center, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaneurol.2016.3541DOI Listing
January 2017

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Prospective Validation of 18F-FDG Brain PET Discriminant Analysis Methods in the Diagnosis of Amyotrophic Lateral Sclerosis.

J Nucl Med 2016 Aug 3;57(8):1238-43. Epub 2016 Mar 3.

Department of Neurology, University Hospitals Leuven, Leuven, Belgium Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven, Leuven, Belgium; and Laboratory of Neurobiology, VIB, Vesalius Research Center, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.115.166272DOI Listing
August 2016

Inside out: the role of nucleocytoplasmic transport in ALS and FTLD.

Acta Neuropathol 2016 08 6;132(2):159-173. Epub 2016 Jun 6.

Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven, 3000, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-016-1586-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947127PMC
August 2016

Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice.

Hum Mol Genet 2016 08 4;25(16):3491-3499. Epub 2016 Jul 4.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddw190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179944PMC
August 2016

RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture.

Stroke 2016 05 29;47(5):1286-93. Epub 2016 Mar 29.

From the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands (R.K., B.H.V., F.G., A.v.d.Z., J.W.B.v.d.S., K.S.H., P.G., P.C.v.R., G.J.E.R., J.H.V., Y.M.R.); Department of Genetics (P.v.d.V., P.D., M.A.S.) and Genomics Coordination Center (P.D., M.A.S.), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Laboratory of Neurobiology, Vesalius Research Center, VIB, Leuven, Belgium (L.d.M., P.V.D.); Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland (L.R.); and Cell Biology, Department of Biology, Science Faculty, Utrecht University, Utrecht, The Netherlands (E.K., J.A.P.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/STROKEAHA.116.012541DOI Listing
May 2016

How robust is ACTIVLIM for the follow-up of activity limitations in patients with neuromuscular diseases?

Neuromuscul Disord 2016 Mar 21;26(3):211-20. Epub 2015 Dec 21.

Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium; Arsalis SPRL, Glabais, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nmd.2015.12.004DOI Listing
March 2016

Neurological picture. FDG-PET findings in three cases of Mills' syndrome.

J Neurol Neurosurg Psychiatry 2016 Feb 28;87(2):222-3. Epub 2015 Apr 28.

Department of Neurology, University Hospitals Leuven, Leuven, Belgium Department of Neurosciences, KU Leuven-University of Leuven, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium Laboratory of Neurobiology, VIB, Vesalius Research Center, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2014-309952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752632PMC
February 2016

Genetic Creutzfeldt-Jakob disease mimicking chronic inflammatory demyelinating polyneuropathy.

Neurol Neuroimmunol Neuroinflamm 2015 Dec 29;2(6):e173. Epub 2015 Oct 29.

Departments of Neurology (D.W., M.S., P.V.D.), Radiology (P.D.), and Pathology (T.T.), University Hospitals Leuven; KU Leuven (M.S.), University of Leuven, Department of Neurosciences, Experimental Neurology, Laboratory for Cognitive Neurology, Leuven; Neurodegenerative Brain Diseases Group (C.V.B.), Department of Molecular Genetics, VIB, Antwerp; Laboratory of Neurogenetics (C.V.B.), Institute Born-Bunge, University of Antwerp, Belgium; Institute of Neurology (G.G.K.), Medical University of Vienna, Austria; KU Leuven (P.V.D.), University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, Leuven; and VIB (P.V.D.), Vesalius Research Center, Laboratory of Neurobiology, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXI.0000000000000173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630682PMC
December 2015

Acute ataxic neuropathy associated with hepatitis E virus infection.

Muscle Nerve 2015 Sep 14;52(3):464-5. Epub 2015 May 14.

Department of Neurology, University Hospitals Leuven and Department of Neurosciences, KU Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.24676DOI Listing
September 2015

A 62-Year-Old Woman with Muscle Weakness.

Clin Chem 2015 Sep;61(9):1133-5

Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium; Department of Microbiology and Immunology, Katholieke Universiteit Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://www.clinchem.org/cgi/doi/10.1373/clinchem.2014.227819
Publisher Site
http://dx.doi.org/10.1373/clinchem.2014.227819DOI Listing
September 2015

Early stages of building a rare disease registry, methods and 2010 data from the Belgian Neuromuscular Disease Registry (BNMDR).

Acta Neurol Belg 2015 Jun 24;115(2):97-104. Epub 2014 Jun 24.

Health Services Research Unit, Department of Public Health and Surveillance, Scientific Institute of Public Health, Health Services Research, 14 rue Juliette Wytsman, 1150, Brussels, Belgium,

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s13760-014-0320-0
Publisher Site
http://dx.doi.org/10.1007/s13760-014-0320-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438257PMC
June 2015

The neonatal sarcoplasmic reticulum Ca2+-ATPase gives a clue to development and pathology in human muscles.

J Muscle Res Cell Motil 2015 Apr 9;36(2):195-203. Epub 2014 Dec 9.

Department of Biochemistry, Faculty of General Medicine, University of Szeged, Dóm tér 9, H-6720, Szeged, Hungary.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10974-014-9403-zDOI Listing
April 2015

Noninvasive ventilation improves sleep in amyotrophic lateral sclerosis: a prospective polysomnographic study.

J Clin Sleep Med 2015 Apr 15;11(5):559-66. Epub 2015 Apr 15.

Leuven University Centre for Sleep/Wake Disorders, Department of Pulmonology, University Hospitals Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5664/jcsm.4704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410930PMC
April 2015

Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.

Stem Cell Reports 2015 Jan 31;4(1):16-24. Epub 2014 Dec 31.

Stem Cell Institute, KU Leuven, 3000 Leuven, Belgium; Stem Cell Biology and Embryology Unit, Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2014.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297877PMC
January 2015

Prevention of intestinal obstruction reveals progressive neurodegeneration in mutant TDP-43 (A315T) mice.

Mol Neurodegener 2014 Jun 17;9:24. Epub 2014 Jun 17.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium.

View Article

Download full-text PDF

Source
http://molecularneurodegeneration.biomedcentral.com/articles
Publisher Site
http://dx.doi.org/10.1186/1750-1326-9-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088917PMC
June 2014