Philip Shaul

Philip Shaul

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Philip Shaul

Philip Shaul

Publications by authors named "Philip Shaul"

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1PubMed Central Citations

Super-Resolution Ultrasound Imaging of Skeletal Muscle Microvascular Dysfunction in an Animal Model of Type 2 Diabetes.

J Ultrasound Med 2019 Oct 31;38(10):2589-2599. Epub 2019 Jan 31.

Department of Bioengineering, University of Texas at Dallas, Richardson, Texas, USA.

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http://dx.doi.org/10.1002/jum.14956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669112PMC
October 2019

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis.

Nature 2019 05 24;569(7757):565-569. Epub 2019 Apr 24.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1038/s41586-019-1140-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631346PMC
May 2019

Identifying genes with tri-modal association with survival and tumor grade in cancer patients.

BMC Bioinformatics 2019 Jan 8;20(1):13. Epub 2019 Jan 8.

Department of Clinical Sciences, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1186/s12859-018-2582-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323748PMC
January 2019

New Insights in the Pathophysiology of Antiphospholipid Syndrome.

Semin Thromb Hemost 2018 Jul 27;44(5):475-482. Epub 2017 Jan 27.

Department of Pediatrics, Center for Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1055/s-0036-1597286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333209PMC
July 2018

Enhanced Liver Regeneration After Partial Hepatectomy in Sterol Regulatory Element-Binding Protein (SREBP)-1c-Null Mice is Associated with Increased Hepatocellular Cholesterol Availability.

Cell Physiol Biochem 2018 22;47(2):784-799. Epub 2018 May 22.

Department of Pathology, Shenzhen University Medical Center, Shenzhen University Health Science Center, Shenzhen, China.

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http://dx.doi.org/10.1159/000490030DOI Listing
July 2018

Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium.

Blood 2018 05 2;131(19):2097-2110. Epub 2018 Mar 2.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1182/blood-2017-11-814681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946764PMC
May 2018

Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells.

Biochim Biophys Acta Mol Cell Biol Lipids 2018 Feb 2;1863(2):199-211. Epub 2017 Dec 2.

Centre de Recherche des Cordeliers, INSERM, UMPC Université Paris 6, Université Paris Descartes Paris 5, CNRS, F-75006 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2017.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742559PMC
February 2018

Sirtuin1 Protects against Systemic Sclerosis-related Pulmonary Fibrosis by Decreasing Proinflammatory and Profibrotic Processes.

Am J Respir Cell Mol Biol 2018 01;58(1):28-39

1 State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences.

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http://dx.doi.org/10.1165/rcmb.2016-0192OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941307PMC
January 2018

Toward optimization of in vivo super-resolution ultrasound imaging using size-selected microbubble contrast agents.

Med Phys 2017 Dec 27;44(12):6304-6313. Epub 2017 Oct 27.

Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA.

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http://dx.doi.org/10.1002/mp.12606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734623PMC
December 2017

Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice.

Endocrinology 2016 Oct 23;157(10):3731-3741. Epub 2016 Aug 23.

Center for Pulmonary and Vascular Biology (K.L.C., J.B., M.U., J.U., L.H., C.M., P.W.S.), Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, 75390; and Departments of Chemistry (S.H.K., J.A.K.), Food Science and Human Nutrition (Z.M.-E.), and Molecular and Integrative Physiology (B.S.K.), University of Illinois at Urbana-Champaign, Urbana, Illinois, 61801.

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http://dx.doi.org/10.1210/en.2015-1629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045504PMC
October 2016

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice.

Diabetes 2016 07 26;65(7):1996-2005. Epub 2016 Apr 26.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX

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http://dx.doi.org/10.2337/db15-1605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915578PMC
July 2016

PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle.

PLoS One 2015 17;10(4):e0124494. Epub 2015 Apr 17.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124494PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401672PMC
April 2016

Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation.

Sci Signal 2016 Mar 15;9(419):ra29. Epub 2016 Mar 15.

Department of Molecular Genetics, University of Texas (UT) Southwestern Medical Center, Dallas, TX 75390, USA. Center for Translational Neurodegeneration Research, UT Southwestern Medical Center, Dallas, TX 75390, USA. Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX 75390, USA. Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, Dallas, TX 75390, USA. Center for Neuroscience, Department of Neuroanatomy, Albert-Ludwigs-University, 79104 Freiburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053773PMC
http://dx.doi.org/10.1126/scisignal.aad5578DOI Listing
March 2016

Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice.

J Lipid Res 2015 May 11;56(5):986-97. Epub 2015 Mar 11.

State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1194/jlr.M054742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409288PMC
May 2015

HDL cholesterol efflux capacity and cardiovascular events.

N Engl J Med 2015 05;372(19):1871-2

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http://dx.doi.org/10.1056/NEJMc1503139DOI Listing
May 2015

IgG receptor FcγRIIB plays a key role in obesity-induced hypertension.

Hypertension 2015 Feb 3;65(2):456-62. Epub 2014 Nov 3.

From the Department of Pediatrics, Section of Neonatology, Baylor College of Medicine, Houston, TX (N.C.S., B.-M.D.B.); and Department of Internal Medicine, Division of Cardiology, Hypertension Section (W.V.) and Department of Pediatrics, Center for Pulmonary and Vascular Biology (K.T., I.S.Y., K.L.C., C.M., P.W.S.), University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419357PMC
February 2015

Role of the endothelium in the metabolic syndrome: IIB or not IIB.

Authors:
Philip W Shaul

Am J Med Sci 2015 Jan;349(1):3-5

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1097/MAJ.0000000000000402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419335PMC
January 2015

Fcγ receptors and ligands and cardiovascular disease.

Circ Res 2015 Jan;116(2):368-84

From the Department of Pediatrics, Center for Pulmonary and Vascular Biology (K.T., N.S., C.M., P.W.S.), and Division of Cardiology, Department of Internal Medicine (A.K., W.V.), University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.302795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331353PMC
January 2015

HDL cholesterol efflux capacity and incident cardiovascular events.

N Engl J Med 2014 Dec 18;371(25):2383-93. Epub 2014 Nov 18.

From the Division of Cardiology, Department of Internal Medicine (A.R., A.K., J.D.B., E.G.G., C.R.A., I.J.N., J.A.L.), and the Center for Pulmonary and Vascular Biology, Department of Pediatrics (I.S.Y., P.W.S.), University of Texas Southwestern Medical Center, Dallas; the Department of Internal Medicine, Emory University, Atlanta (K.E.W.); and the Departments of Genetics and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (D.R.R.).

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http://dx.doi.org/10.1056/NEJMoa1409065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308988PMC
December 2014

Antiphospholipid antibodies attenuate endothelial repair and promote neointima formation in mice.

J Am Heart Assoc 2014 Oct 14;3(5):e001369. Epub 2014 Oct 14.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX (V.U., W.R.L., S.K., P.W.S., C.M.).

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http://dx.doi.org/10.1161/JAHA.114.001369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323803PMC
October 2014

Genetic variants of ApoE and ApoER2 differentially modulate endothelial function.

Proc Natl Acad Sci U S A 2014 Sep 2;111(37):13493-8. Epub 2014 Sep 2.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, and

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http://dx.doi.org/10.1073/pnas.1402106111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169937PMC
September 2014

Bazedoxifene and conjugated estrogen prevent diet-induced obesity, hepatic steatosis, and type 2 diabetes in mice without impacting the reproductive tract.

Am J Physiol Endocrinol Metab 2014 Aug 17;307(3):E345-54. Epub 2014 Jun 17.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas; and

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http://dx.doi.org/10.1152/ajpendo.00653.2013DOI Listing
August 2014

The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha.

Cell Metab 2014 Jul 19;20(1):172-82. Epub 2014 Jun 19.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131140022
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http://dx.doi.org/10.1016/j.cmet.2014.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098728PMC
July 2014

Recent insights into non-nuclear actions of estrogen receptor alpha.

Steroids 2014 Mar 16;81:64-9. Epub 2013 Nov 16.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9063, USA. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2013.11.002DOI Listing
March 2014

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

Cell Rep 2013 Nov 7;5(3):637-45. Epub 2013 Nov 7.

Department of Pediatrics, Division of Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950897PMC
November 2013

Regulation of signal transduction by HDL.

J Lipid Res 2013 Sep 18;54(9):2315-24. Epub 2013 May 18.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1194/jlr.R039479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735931PMC
September 2013

LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity.

J Clin Invest 2013 Aug 8;123(8):3488-97. Epub 2013 Jul 8.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1172/JCI66533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726156PMC
August 2013

Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass.

Mol Endocrinol 2013 Apr 26;27(4):649-56. Epub 2013 Feb 26.

Division of Endocrinology and Metabolism, University of Arkansas for Medical Sciences, 4301 West Markham Street, MS 587, Little Rock, Arkansas 72205, USA.

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https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
Publisher Site
http://dx.doi.org/10.1210/me.2012-1368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607700PMC
April 2013

Point mutations in the ERα Gαi binding domain segregate nonnuclear from nuclear receptor function.

Mol Endocrinol 2013 Jan 14;27(1):2-11. Epub 2012 Dec 14.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/me.2011-1378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545213PMC
January 2013

Functions of scavenger receptor class B, type I in atherosclerosis.

Curr Opin Lipidol 2012 Oct;23(5):487-93

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1097/MOL.0b013e328357ba61DOI Listing
October 2012

Novel biological functions of high-density lipoprotein cholesterol.

Circ Res 2012 Sep;111(8):1079-90

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.258673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500606PMC
September 2012

Regulation of eNOS in caveolae.

Adv Exp Med Biol 2012 ;729:51-62

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1007/978-1-4614-1222-9_4DOI Listing
May 2012

Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function.

Circ Res 2011 Oct 22;109(10):1132-40. Epub 2011 Sep 22.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.254573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215097PMC
October 2011

Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species.

Am J Physiol Cell Physiol 2011 Sep 8;301(3):C695-704. Epub 2011 Jun 8.

Dept. of Surgery, The Univ. of Texas Southwestern Medical Cente at Dallas, 75390-9156, USA.

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http://dx.doi.org/10.1152/ajpcell.00322.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174570PMC
September 2011

PON-dering differences in HDL function in coronary artery disease.

J Clin Invest 2011 Jul 23;121(7):2545-8. Epub 2011 Jun 23.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1172/JCI57671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223844PMC
July 2011

Inhaled nitric oxide and bronchopulmonary dysplasia.

Pediatrics 2011 Jul;128(1):e255-6; author reply e256-7

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http://dx.doi.org/10.1542/peds.2011-1270ADOI Listing
July 2011

Non-nuclear estrogen receptor signaling in the endothelium.

J Biol Chem 2011 Apr 22;286(17):14737-43. Epub 2011 Feb 22.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.R110.191791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083154PMC
April 2011

27-Hydroxycholesterol: the first identified endogenous SERM.

Trends Endocrinol Metab 2011 Apr 23;22(4):130-5. Epub 2011 Feb 23.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. michihisa.umetani@utsouthwestern

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http://dx.doi.org/10.1016/j.tem.2011.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070823PMC
April 2011

Patent ductus arteriosus ligation alters pulmonary gene expression in preterm baboons.

Pediatr Res 2011 Mar;69(3):212-6

Pharmaceutical Discovery Division, SRI International, Menlo Park, California 94025, USA.

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http://dx.doi.org/10.1203/PDR.0b013e3182084f8dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065199PMC
March 2011

The effects of postnatal estrogen therapy on brain development in preterm baboons.

Am J Obstet Gynecol 2011 Feb 11;204(2):177.e8-14. Epub 2010 Nov 11.

Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.ajog.2010.09.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032810PMC
February 2011

New Insights into the Molecular Basis of the Antiphospholipid Syndrome.

Drug Discov Today Dis Mech 2011 ;8(1-2):e47-e52

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.ddmec.2011.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389810PMC
January 2011

Signaling by the high-affinity HDL receptor scavenger receptor B type I.

Arterioscler Thromb Vasc Biol 2010 Feb;30(2):144-50

Division of Pulmonary and Vascular Biology, the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.196170DOI Listing
February 2010

G-CSF exerts dual effects on endothelial cells--opposing actions of direct eNOS induction versus indirect CRP elevation.

J Mol Cell Cardiol 2008 Nov 15;45(5):670-8. Epub 2008 Jul 15.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.yjmcc.2008.07.002DOI Listing
November 2008

The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity.

Circ Res 2008 Feb 3;102(4):480-7. Epub 2008 Jan 3.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, USA.

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http://circres.ahajournals.org/content/102/4/480.full.pdf
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http://circres.ahajournals.org/cgi/doi/10.1161/CIRCRESAHA.10
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.107.159079DOI Listing
February 2008

27-hydroxycholesterol is an endogenous selective estrogen receptor modulator.

Mol Endocrinol 2008 Jan 13;22(1):65-77. Epub 2007 Sep 13.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1210/me.2007-0383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194632PMC
January 2008

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.

Nat Med 2007 Oct 16;13(10):1185-92. Epub 2007 Sep 16.

Department of Pharmacology and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, Texas 75390-9050, USA.

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http://dx.doi.org/10.1038/nm1641DOI Listing
October 2007

Biochemical consequences of the NOS3 Glu298Asp variation in human endothelium: altered caveolar localization and impaired response to shear.

FASEB J 2007 Sep 20;21(11):2655-63. Epub 2007 Apr 20.

Center for Cardiovascular Medicine, Columbus Children's Research Institute, 700 Children's Dr., Columbus, OH 43205, USA.

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http://dx.doi.org/10.1096/fj.06-7088comDOI Listing
September 2007

Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1.

Am J Respir Cell Mol Biol 2007 Jul 22;37(1):38-47. Epub 2007 Mar 22.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9063, USA.

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http://dx.doi.org/10.1165/rcmb.2006-0353OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899351PMC
July 2007

Nitric oxide attenuates epithelial-mesenchymal transition in alveolar epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2007 Jul 11;293(1):L212-21. Epub 2007 May 11.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1152/ajplung.00475.2006DOI Listing
July 2007

Role of high-density lipoprotein and scavenger receptor B type I in the promotion of endothelial repair.

Trends Cardiovasc Med 2007 Jul;17(5):156-61

Division of Pulmonary and Vascular Biology, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.tcm.2007.03.005DOI Listing
July 2007

Direct interactions with G α i and G βγ mediate nongenomic signaling by estrogen receptor α .

Mol Endocrinol 2007 Jun 3;21(6):1370-80. Epub 2007 Apr 3.

Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1210/me.2006-0360DOI Listing
June 2007

The cold, hard truth about pediatric research.

Authors:
Philip W Shaul

Pediatr Res 2007 Apr;61(4):506-9

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1203/pdr.0b013e3180337279DOI Listing
April 2007

C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice.

Circulation 2007 Feb 5;115(8):1020-8. Epub 2007 Feb 5.

Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.106.6
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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.664854DOI Listing
February 2007

Endothelial and antithrombotic actions of HDL.

Circ Res 2006 Jun;98(11):1352-64

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9063, USA.

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http://dx.doi.org/10.1161/01.RES.0000225982.01988.93DOI Listing
June 2006

Circulating cardiovascular disease risk factors and signaling in endothelial cell caveolae.

Cardiovasc Res 2006 Apr 15;70(1):31-41. Epub 2006 Mar 15.

Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, USA.

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http://dx.doi.org/10.1016/j.cardiores.2006.01.025DOI Listing
April 2006

Surfactant composition and function in a primate model of infant chronic lung disease: effects of inhaled nitric oxide.

Pediatr Res 2006 Jan 2;59(1):157-62. Epub 2005 Dec 2.

Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 19104, USA.

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http://dx.doi.org/10.1203/01.pdr.0000190664.69081.f1DOI Listing
January 2006

Pulmonary and systemic nitric oxide metabolites in a baboon model of neonatal chronic lung disease.

Am J Respir Cell Mol Biol 2005 Dec 15;33(6):582-8. Epub 2005 Sep 15.

Joseph Stokes Jr. Research Institute, Children's Hospital of Philadelphia, 3516 Civic Center Blvd., 416D Abramson Research Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0182OCDOI Listing
December 2005

Effect of ductus ligation on cardiopulmonary function in premature baboons.

Am J Respir Crit Care Med 2005 Dec 22;172(12):1569-74. Epub 2005 Sep 22.

Southwest Foundation for Biomedical Research, San Antonio, TX, USA.

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http://dx.doi.org/10.1164/rccm.200502-230OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718457PMC
December 2005

FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase.

Circ Res 2005 Nov 3;97(11):1124-31. Epub 2005 Nov 3.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1161/01.RES.0000194323.77203.feDOI Listing
November 2005

Caveolin-1 is not required for murine intestinal cholesterol transport.

J Biol Chem 2005 Jul 26;280(30):28103-9. Epub 2005 May 26.

Department of Physiology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M504609200DOI Listing
July 2005

Molecular basis of estrogen-induced cyclooxygenase type 1 upregulation in endothelial cells.

Circ Res 2005 Mar 10;96(5):518-25. Epub 2005 Feb 10.

Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, TX 75390, USA.

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http://dx.doi.org/10.1161/01.RES.0000158967.96231.88DOI Listing
March 2005

Dissecting the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol: role of ERalpha domains with known nuclear functions.

Mol Endocrinol 2005 Feb 14;19(2):277-89. Epub 2004 Oct 14.

Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/me.2004-0008DOI Listing
February 2005

HDL action on the vascular wall: is the answer NO?

J Clin Invest 2004 Feb;113(4):509-13

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1172/JCI21072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC338271PMC
February 2004

Hypoxia-induced left ventricular dysfunction in myoglobin-deficient mice.

Am J Physiol Heart Circ Physiol 2003 Nov 24;285(5):H2132-41. Epub 2003 Jul 24.

Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8573, USA.

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http://dx.doi.org/10.1152/ajpheart.00147.2003DOI Listing
November 2003

HDL stimulation of endothelial nitric oxide synthase: a novel mechanism of HDL action.

Trends Cardiovasc Med 2003 Aug;13(6):226-31

Department of Pediatrics, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/s1050-1738(03)00098-7DOI Listing
August 2003

Pulmonary NO synthase expression is attenuated in a fetal baboon model of chronic lung disease.

Am J Physiol Lung Cell Mol Physiol 2003 May 10;284(5):L749-58. Epub 2003 Jan 10.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75390, USA.

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http://dx.doi.org/10.1152/ajplung.00334.2002DOI Listing
May 2003

High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases.

J Biol Chem 2003 Mar 2;278(11):9142-9. Epub 2003 Jan 2.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M211394200DOI Listing
March 2003

Vasomodulation by skeletal muscle-derived nitric oxide requires alpha-syntrophin-mediated sarcolemmal localization of neuronal Nitric oxide synthase.

Circ Res 2003 Mar 13;92(5):554-60. Epub 2003 Feb 13.

Department of Internal Medicine, Division of Hypertension, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Tex 75390-8586, USA.

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http://dx.doi.org/10.1161/01.RES.0000061570.83105.52DOI Listing
March 2003

Endothelial nitric oxide synthase, caveolae and the development of atherosclerosis.

Authors:
Philip W Shaul

J Physiol 2003 Feb 10;547(Pt 1):21-33. Epub 2003 Jan 10.

Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9063, USA.

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http://dx.doi.org/10.1113/jphysiol.2002.031534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2342632PMC
February 2003

Developmental changes in nitric oxide synthase isoform expression and nitric oxide production in fetal baboon lung.

Am J Physiol Lung Cell Mol Physiol 2002 Dec 7;283(6):L1192-9. Epub 2002 Jul 7.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75390, USA.

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http://dx.doi.org/10.1152/ajplung.00112.2002DOI Listing
December 2002

Estrogen causes dynamic alterations in endothelial estrogen receptor expression.

Circ Res 2002 Nov;91(9):814-20

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75390-9063, USA.

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http://dx.doi.org/10.1161/01.res.0000038304.62046.4cDOI Listing
November 2002

Estrogen modulation of endothelial nitric oxide synthase.

Endocr Rev 2002 Oct;23(5):665-86

Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/er.2001-0045DOI Listing
October 2002

Demonstration that C-reactive protein decreases eNOS expression and bioactivity in human aortic endothelial cells.

Circulation 2002 Sep;106(12):1439-41

Laboratory for Atherosclerosis and Metabolic Research, Department of Pathology, UC Davis Medical Center, Sacramento, Calif 95817, USA.

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http://dx.doi.org/10.1161/01.cir.0000033116.22237.f9DOI Listing
September 2002

Conventional estrogen receptors are found in the plasma membrane of vaginal epithelial cells of the rat.

Steroids 2002 Aug;67(9):757-64

Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500007, India.

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http://dx.doi.org/10.1016/s0039-128x(02)00028-4DOI Listing
August 2002

Estrogen acutely activates prostacyclin synthesis in ovine fetal pulmonary artery endothelium.

Am J Respir Cell Mol Biol 2002 May;26(5):610-6

Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1165/ajrcmb.26.5.4528DOI Listing
May 2002

ERbeta has nongenomic action in caveolae.

Mol Endocrinol 2002 May;16(5):938-46

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1210/mend.16.5.0827DOI Listing
May 2002