Publications by authors named "Philip S Tsao"

100Publications

The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study.

PLoS Med 2020 Sep 11;17(9):e1003302. Epub 2020 Sep 11.

Corporal Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1003302DOI Listing
September 2020

Involvement of Myeloid Cells and Noncoding RNA in Abdominal Aortic Aneurysm Disease.

Antioxid Redox Signal 2020 Sep 16;33(9):602-620. Epub 2020 Apr 16.

Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1089/ars.2020.8035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455479PMC
September 2020

Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies.

Am J Hum Genet 2019 10 26;105(4):763-772. Epub 2019 Sep 26.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; VA Palo Alto Epidemiology Research and Information Center for Genomics, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817526PMC
October 2019

Controlled isoflurane anesthesia exposure is required for reliable behavioral testing in murine surgical models.

J Pharmacol Sci 2019 May 11;140(1):106-108. Epub 2019 May 11.

Department of Pharmacology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.jphs.2019.03.007DOI Listing
May 2019

Therapeutic perspective on vascular cognitive impairment.

Pharmacol Res 2019 08 17;146:104266. Epub 2019 May 17.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States; VA Palo Alto Health Care System, Palo Alto, CA, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S10436618193052
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http://dx.doi.org/10.1016/j.phrs.2019.104266DOI Listing
August 2019

microRNA-based biomarker for dementia.

Aging (Albany NY) 2019 03;11(5):1329-1330

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://www.aging-us.com/article/101868/text
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http://dx.doi.org/10.18632/aging.101868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428090PMC
March 2019

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

Authors:
Ayush Giri Jacklyn N Hellwege Jacob M Keaton Jihwan Park Chengxiang Qiu Helen R Warren Eric S Torstenson Csaba P Kovesdy Yan V Sun Otis D Wilson Cassianne Robinson-Cohen Christianne L Roumie Cecilia P Chung Kelly A Birdwell Scott M Damrauer Scott L DuVall Derek Klarin Kelly Cho Yu Wang Evangelos Evangelou Claudia P Cabrera Louise V Wain Rojesh Shrestha Brian S Mautz Elvis A Akwo Muralidharan Sargurupremraj Stéphanie Debette Michael Boehnke Laura J Scott Jian'an Luan Jing-Hua Zhao Sara M Willems Sébastien Thériault Nabi Shah Christopher Oldmeadow Peter Almgren Ruifang Li-Gao Niek Verweij Thibaud S Boutin Massimo Mangino Ioanna Ntalla Elena Feofanova Praveen Surendran James P Cook Savita Karthikeyan Najim Lahrouchi Chunyu Liu Nuno Sepúlveda Tom G Richardson Aldi Kraja Philippe Amouyel Martin Farrall Neil R Poulter Markku Laakso Eleftheria Zeggini Peter Sever Robert A Scott Claudia Langenberg Nicholas J Wareham David Conen Colin Neil Alexander Palmer John Attia Daniel I Chasman Paul M Ridker Olle Melander Dennis Owen Mook-Kanamori Pim van der Harst Francesco Cucca David Schlessinger Caroline Hayward Tim D Spector Marjo-Riitta Jarvelin Branwen J Hennig Nicholas J Timpson Wei-Qi Wei Joshua C Smith Yaomin Xu Michael E Matheny Edward E Siew Cecilia Lindgren Karl-Heinz Herzig George Dedoussis Joshua C Denny Bruce M Psaty Joanna M M Howson Patricia B Munroe Christopher Newton-Cheh Mark J Caulfield Paul Elliott J Michael Gaziano John Concato Peter W F Wilson Philip S Tsao Digna R Velez Edwards Katalin Susztak Christopher J O'Donnell Adriana M Hung Todd L Edwards

Nat Genet 2019 01 21;51(1):51-62. Epub 2018 Dec 21.

Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.

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http://www.nature.com/articles/s41588-018-0303-9
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http://dx.doi.org/10.1038/s41588-018-0303-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365102PMC
January 2019

An Automated Algorithm to Quantify Collagen Distribution in Aortic Wall.

J Histochem Cytochem 2019 04 19;67(4):267-274. Epub 2018 Nov 19.

Department of Chemical and Materials Engineering, San José State University, San José, CA.

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http://journals.sagepub.com/doi/10.1369/0022155418814231
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http://dx.doi.org/10.1369/0022155418814231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437342PMC
April 2019

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 12;50(12):1755

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://www.nature.com/articles/s41588-018-0297-3
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http://dx.doi.org/10.1038/s41588-018-0297-3DOI Listing
December 2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 10 17;50(10):1412-1425. Epub 2018 Sep 17.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0205-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284793PMC
October 2018

Decoding the Genomics of Abdominal Aortic Aneurysm.

Cell 2018 09;174(6):1361-1372.e10

Department of Genetics, Center for Genomics and Personalized Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.07.021DOI Listing
September 2018

Non-coding RNAs in aneurysmal aortopathy.

Vascul Pharmacol 2019 03 15;114:110-121. Epub 2018 Jun 15.

Cardiovascular Medicine and Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA; VA Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vph.2018.06.008DOI Listing
March 2019

Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm.

Arterioscler Thromb Vasc Biol 2018 08;38(8):1796-1805

From the Division of Cardiovascular Medicine, Cardiovascular Institute, Stanford University School of Medicine, CA (M.A., N.G.K., A.J., M.U.W., Y.W., YK., K.T., U.R., I.N.S., L.M., J.M.S., J.C.W., P.S.T.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652227PMC
August 2018

H19 Induces Abdominal Aortic Aneurysm Development and Progression.

Circulation 2018 10;138(15):1551-1568

Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar (D.Y.L., A. Busch, J.P., S.L., H.-H.E., L.M.), Technical University Munich, and German Center for Cardiovascular Research (DZHK), partner site Munich, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.032184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193867PMC
October 2018

MicroRNA-Mediated Therapy Modulating Blood-Brain Barrier Disruption Improves Vascular Cognitive Impairment.

Arterioscler Thromb Vasc Biol 2018 06 12;38(6):1392-1406. Epub 2018 Apr 12.

From the Division of Cardiovascular Medicine (K.T., J.M.S., A.C.D., M.U.W., T.Y., J.M., U.R., M.A., I.N.S., A.J., P.S.T.)

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http://dx.doi.org/10.1161/ATVBAHA.118.310822DOI Listing
June 2018

Exome-wide association study of plasma lipids in >300,000 individuals.

Authors:
Dajiang J Liu Gina M Peloso Haojie Yu Adam S Butterworth Xiao Wang Anubha Mahajan Danish Saleheen Connor Emdin Dewan Alam Alexessander Couto Alves Philippe Amouyel Emanuele Di Angelantonio Dominique Arveiler Themistocles L Assimes Paul L Auer Usman Baber Christie M Ballantyne Lia E Bang Marianne Benn Joshua C Bis Michael Boehnke Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Ivan Brandslund Morris Brown Fabio Busonero Mark J Caulfield John C Chambers Daniel I Chasman Y Eugene Chen Yii-Der Ida Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu John M Connell Francesco Cucca L Adrienne Cupples Scott M Damrauer Gail Davies Ian J Deary George Dedoussis Joshua C Denny Anna Dominiczak Marie-Pierre Dubé Tapani Ebeling Gudny Eiriksdottir Tõnu Esko Aliki-Eleni Farmaki Mary F Feitosa Marco Ferrario Jean Ferrieres Ian Ford Myriam Fornage Paul W Franks Timothy M Frayling Ruth Frikke-Schmidt Lars G Fritsche Philippe Frossard Valentin Fuster Santhi K Ganesh Wei Gao Melissa E Garcia Christian Gieger Franco Giulianini Mark O Goodarzi Harald Grallert Niels Grarup Leif Groop Megan L Grove Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Joel N Hirschhorn Oddgeir L Holmen Jennifer Huffman Yong Huo Kristian Hveem Sehrish Jabeen Anne U Jackson Johanna Jakobsdottir Marjo-Riitta Jarvelin Gorm B Jensen Marit E Jørgensen J Wouter Jukema Johanne M Justesen Pia R Kamstrup Stavroula Kanoni Fredrik Karpe Frank Kee Amit V Khera Derek Klarin Heikki A Koistinen Jaspal S Kooner Charles Kooperberg Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo Lakka Claudia Langenberg Anne Langsted Lenore J Launer Torsten Lauritzen David C M Liewald Li An Lin Allan Linneberg Ruth J F Loos Yingchang Lu Xiangfeng Lu Reedik Mägi Anders Malarstig Ani Manichaikul Alisa K Manning Pekka Mäntyselkä Eirini Marouli Nicholas G D Masca Andrea Maschio James B Meigs Olle Melander Andres Metspalu Andrew P Morris Alanna C Morrison Antonella Mulas Martina Müller-Nurasyid Patricia B Munroe Matt J Neville Jonas B Nielsen Sune F Nielsen Børge G Nordestgaard Jose M Ordovas Roxana Mehran Christoper J O'Donnell Marju Orho-Melander Cliona M Molony Pieter Muntendam Sandosh Padmanabhan Colin N A Palmer Dorota Pasko Aniruddh P Patel Oluf Pedersen Markus Perola Annette Peters Charlotta Pisinger Giorgio Pistis Ozren Polasek Neil Poulter Bruce M Psaty Daniel J Rader Asif Rasheed Rainer Rauramaa Dermot F Reilly Alex P Reiner Frida Renström Stephen S Rich Paul M Ridker John D Rioux Neil R Robertson Dan M Roden Jerome I Rotter Igor Rudan Veikko Salomaa Nilesh J Samani Serena Sanna Naveed Sattar Ellen M Schmidt Robert A Scott Peter Sever Raquel S Sevilla Christian M Shaffer Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Albert V Smith Blair H Smith Sangeetha Somayajula Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kathleen E Stirrups Nathan Stitziel Konstantin Strauch Heather M Stringham Praveen Surendran Hayato Tada Alan R Tall Hua Tang Jean-Claude Tardif Kent D Taylor Stella Trompet Philip S Tsao Jaakko Tuomilehto Anne Tybjaerg-Hansen Natalie R van Zuydam Anette Varbo Tibor V Varga Jarmo Virtamo Melanie Waldenberger Nan Wang Nick J Wareham Helen R Warren Peter E Weeke Joshua Weinstock Jennifer Wessel James G Wilson Peter W F Wilson Ming Xu Hanieh Yaghootkar Robin Young Eleftheria Zeggini He Zhang Neil S Zheng Weihua Zhang Yan Zhang Wei Zhou Yanhua Zhou Magdalena Zoledziewska Joanna M M Howson John Danesh Mark I McCarthy Chad A Cowan Goncalo Abecasis Panos Deloukas Kiran Musunuru Cristen J Willer Sekar Kathiresan

Nat Genet 2017 Dec 30;49(12):1758-1766. Epub 2017 Oct 30.

Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709146PMC
December 2017

Cloud-based interactive analytics for terabytes of genomic variants data.

Bioinformatics 2017 Dec;33(23):3709-3715

VA Palo Alto Health Care System, Palo Alto Epidemiology Research and Information Center for Genomics, CA 94304, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860318PMC
December 2017

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells.

Dev Cell 2016 11 10;39(4):491-507. Epub 2016 Nov 10.

Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2016.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130110PMC
November 2016

Dietary fructose in pregnancy induces hyperglycemia, hypertension, and pathologic kidney and liver changes in a rodent model.

Pregnancy Hypertens 2015 Oct 12;5(4):308-14. Epub 2015 Aug 12.

Department of Urology, School of Medicine, Stanford University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.preghy.2015.08.002DOI Listing
October 2015

Diabetic Cardiovascular Disease Induced by Oxidative Stress.

Int J Mol Sci 2015 Oct 23;16(10):25234-63. Epub 2015 Oct 23.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.3390/ijms161025234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632800PMC
October 2015

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model.

Circ Res 2015 Sep 19;117(8):720-30. Epub 2015 Aug 19.

From the Division of Cardiology, Department of Medicine, Stanford Cardiovascular Institute (J.R., A.E., E.T., U.R., O.J.A., O.S., N.G.K., E.N., M.W., P.S.T., J.D.G., J.C.W.) and Department of Pathology (A.J.C.), Stanford University School of Medicine, CA; Department for Research and Development, Veterans Administration Palo Alto Health Care System, CA (P.S.T.); Institute of Pharmacology, Heart Research Center, University Medical Center, Georg-August-University and German Center for Cardiovascular Research, Göttingen, Germany (M.T., T.M., W.H.Z.); and Center for Biomedicine and Genetics (V.C.C., L.A.C.) and Center for Applied Technology Development, Beckman Research Institute (A.J.C.), City of Hope, Duarte, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679370PMC
September 2015

Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus.

Circ Res 2015 Aug 24;117(6):513-24. Epub 2015 Jul 24.

From the Division of Cardiovascular Medicine (U.R., I.N.S., Y.K., W.H.Z., M.A., A.J., F.N., R.T., K.T., A.D., J.M.S., P.S.T.), and Cardiovascular Institute (U.R., Y.K., K.P., J.K.H., F.C.E., M.A., A.J., F.N., K.T., J.M.S., P.S.T.), Stanford University School of Medicine, Stanford, CA; VA Palo Alto Health Care System, Palo Alto, CA (U.R., I.N.S., Y.K., W.H.Z., M.A., A.J., K.T., A.D., J.M.S., P.S.T.); Heart Center, Georg-August-University Göttingen, Göttingen, Germany (U.R., G.H.); Departments of Medicine (E.C., S.E., L.M.) and Cell and Molecular Biology (F.S.), Karolinska Institute, Stockholm, Sweden; Department of Nephrology and Hypertension, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany (C.W.); and Division of Cardiovascular Medicine and Intensive Care Medicine, Saint Mary's Hospital, Siegen, Germany (M.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553105PMC
August 2015

Local MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis.

Arterioscler Thromb Vasc Biol 2015 Sep 16;35(9):1945-53. Epub 2015 Jul 16.

From the Department of Cardiovascular Surgery, TSI-Laboratory (D.W., T.D., M.S., S.S.) and Department of Cardiovascular Surgery (T.D., H.R.), University Heart Center Hamburg, Hamburg, Germany; Department of Cardiovascular Surgery, Cardiovascular Research Center Hamburg (CVRC) and DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (D.W., T.D., M.S., S.S.); Atherosclerosis Research Unit, Department of Medicine, Karolinska Institute, CMM L8:03, Stockholm, Sweden (E.C., S.M.E., H.J., Y.L., A.B., L.M.); Unit of Physiology, Pathophysiology, and Experimental Endocrinology, University of Veterinary Medicine, Vienna, Austria (R.G.E.); Department of Cardiology Asklepios Clinic St. Georg, Hamburg, Germany (C.-H.H.); Translumina GmbH, Hechingen, Germany (B.B.); Department of Cardiothoracic Surgery, Stanford Cardiovascular Institute, Stanford University, CA (R.C.R., S.S.); Department of Cardiovascular Medicine, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA (J.M.S., P.S.T.); and Department of Cardiovascular Medicine, Stanford Cardiovascular Institute, Stanford University, CA (J.M.S., P.S.T.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552606PMC
September 2015

Segmental aortic stiffening contributes to experimental abdominal aortic aneurysm development.

Circulation 2015 May 22;131(20):1783-95. Epub 2015 Apr 22.

From Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (U.R., I.N.S., R.T., F.N., Y.K., M.A., A.D., A.J., J.MS., P.S.T.); Cardiovascular Institute, Stanford University School of Medicine, CA (U.R., A.M.Z., F.N., M.B., F.C.E., Y.K., M.A., R.L.D., J.M.S., P.S.T.); VA Palo Alto Health Care System, CA (U.R., I.N.S., Y.K., M.A., A.D., A.J., J.M.S., P.S.T.); Department of Mechanical Engineering, Stanford University School of Medicine, CA (A.M.Z., E.K.); Department of Cardiothoracic Surgery, Stanford University School of Medicine, CA (F.C.E., E.K.); Department of Medicine, Karolinska Institute, Stockholm, Sweden (S.E., L.M.); Center for Vascular Medicine, Zwickau, Germany (T.H.); Division of Cardiovascular Medicine and Intensive Care Medicine, Saint Mary's Hospital, Siegen, Germany (M.B.); Division of Vascular Surgery, Stanford University School of Medicine, CA (R.L.D.); and Department of Bioengineering, Stanford University School of Medicine, CA (E.K.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439288PMC
May 2015

Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure.

Sci Rep 2015 Apr 13;5:9704. Epub 2015 Apr 13.

University of Cologne, Heart Center, Department of Cardiology and Cologne Cardiovascular Research Center, Cologne, Germany.

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http://dx.doi.org/10.1038/srep09704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394753PMC
April 2015

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.

Nat Commun 2014 Oct 31;5:5214. Epub 2014 Oct 31.

1] Division of Cardiovascular Medicine, Stanford University, Falk CVRB, 300 Pasteur Drive, Stanford, California 94305, USA [2] VA Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, California 94304, USA.

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http://dx.doi.org/10.1038/ncomms6214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217126PMC
October 2014

Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm.

Circ Res 2014 Oct;115(10):812-3

From the Division of Cardiovascular Medicine, Stanford University School of Medicine, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323148PMC
October 2014

Red blood cells serve as intravascular carriers of myeloperoxidase.

J Mol Cell Cardiol 2014 Sep 26;74:353-63. Epub 2014 Jun 26.

Heart Center, Department of Cardiology and Cologne Cardiovascular Research Center, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2014.06.009DOI Listing
September 2014

New ways to dismantle a ticking time bomb: microRNA 712/205 and abdominal aortic aneurysm development.

Arterioscler Thromb Vasc Biol 2014 Jul;34(7):1339-40

From the Department of Medicine, Karolinska Institute and University Hospital, Stockholm, Sweden (L.M.); Division of Cardiovascular Medicine, Stanford University, CA (J.M.S., P.S.T.); and Division of Cardiovascular Medicine, VA Palo Alto Health Care System, CA (J.M.S., P.S.T.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176906PMC
July 2014

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury.

Nature 2014 May 20;509(7502):641-4. Epub 2014 Apr 20.

1] TSI-laboratory, University Heart Center Hamburg, Martinistraße 52, 20246 Hamburg, Germany [2] Cardiovascular Research Center Hamburg (CVRC) and DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany [3] Cardiovascular Surgery, University Heart Center Hamburg, Martinistraße 52, 20246 Hamburg, Germany [4] Department of Cardiothoracic Surgery and Stanford Cardiovascular Institute, Stanford University, 300 Pasteur Drive, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature13232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323184PMC
May 2014

Pathogenesis of abdominal aortic aneurysms: microRNAs, proteases, genetic associations.

Annu Rev Med 2014 21;65:49-62. Epub 2013 Nov 21.

Department of Medicine, Karolinska Institute, Stockholm, Sweden; email:

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http://dx.doi.org/10.1146/annurev-med-101712-174206DOI Listing
September 2014

Hemodynamic regulation of reactive oxygen species: implications for vascular diseases.

Antioxid Redox Signal 2014 Feb 17;20(6):914-28. Epub 2013 Sep 17.

1 Division of Cardiovascular Medicine, Stanford University School of Medicine , Stanford, California.

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http://dx.doi.org/10.1089/ars.2013.5507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924901PMC
February 2014

MicroRNA-29b regulation of abdominal aortic aneurysm development.

Trends Cardiovasc Med 2014 Jan 18;24(1):1-6. Epub 2013 Jul 18.

Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcm.2013.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815986PMC
January 2014

Micromanaging abdominal aortic aneurysms.

Int J Mol Sci 2013 Jul 11;14(7):14374-94. Epub 2013 Jul 11.

Department of Medicine, Karolinska Institute, Stockholm SE-17176, Sweden.

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http://dx.doi.org/10.3390/ijms140714374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742249PMC
July 2013

MicroRNAs in Abdominal Aortic Aneurysm.

Curr Vasc Pharmacol 2015 ;13(3):280-90

Stanford University, Stanford School of Medicine, Division of Cardiovascular Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.2174/15701611113119990015DOI Listing
April 2016

Prospective transcriptomic pathway analysis of human lymphatic vascular insufficiency: identification and validation of a circulating biomarker panel.

PLoS One 2012 18;7(12):e52021. Epub 2012 Dec 18.

Stanford Center for Lymphatic and Venous Disorders, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525657PMC
June 2013

In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake.

Peptides 2012 Oct 10;37(2):320-6. Epub 2012 Aug 10.

Department of Medicine/Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305, United States.

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October 2012

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

J Am Coll Cardiol 2012 Aug;60(8):722-9

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.jacc.2012.01.078DOI Listing
August 2012

Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling.

Cardiovasc Res 2012 Jul 22;95(2):147-55. Epub 2012 Feb 22.

Department of Medicine, Division of Cardiology, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRC, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1093/cvr/cvs098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388815PMC
July 2012

Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.

J Clin Invest 2012 Feb 24;122(2):497-506. Epub 2012 Jan 24.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1172/JCI61598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266800PMC
February 2012

Three-dimensional microstructural changes in murine abdominal aortic aneurysms quantified using immunofluorescent array tomography.

J Histochem Cytochem 2012 Feb 1;60(2):97-109. Epub 2011 Dec 1.

Department of Bioengineering, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1369/0022155411433066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351119PMC
February 2012

miR-29b participates in early aneurysm development in Marfan syndrome.

Circ Res 2012 Jan 23;110(2):312-24. Epub 2011 Nov 23.

Department of Cardiothoracic Surgery, 300 Pasteur Drive, Falk Cardiovascular Research Building, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.253740DOI Listing
January 2012

Selective Glucocorticoid Receptor (GR-II) Antagonist Reduces Body Weight Gain in Mice.

J Nutr Metab 2011 28;2011:235389. Epub 2011 Jul 28.

Department of Cardiovascular Medicine, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1155/2011/235389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146995PMC
November 2011

Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm.

Physiol Genomics 2011 Sep 28;43(17):993-1003. Epub 2011 Jun 28.

Division of Cardiovascular Medicine, Stanford University Medical Center, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00044.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180735PMC
September 2011

Apelin and insulin resistance: another arrow for the quiver?

J Diabetes 2011 Sep;3(3):225-31

Department of Medicine/Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1111/j.1753-0407.2011.00132.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156858PMC
September 2011

Asymmetric dimethylarginine impairs fibrinolytic activity in human umbilical vein endothelial cells via p38 MAPK and NF-κB pathways.

Thromb Res 2011 Jul 22;128(1):42-6. Epub 2011 Mar 22.

The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.

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July 2011

Assessment of elastase-induced murine abdominal aortic aneurysms: comparison of ultrasound imaging with in situ video microscopy.

J Biomed Biotechnol 2011 6;2011:252141. Epub 2011 Feb 6.

Division of Cardiovascular Medicine, Stanford University School of Medicine, CA, USA.

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http://dx.doi.org/10.1155/2011/252141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038624PMC
June 2011

Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.

PLoS One 2010 Dec 13;5(12):e14301. Epub 2010 Dec 13.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001469PMC
December 2010

Human ferritin cages for imaging vascular macrophages.

Biomaterials 2011 Feb 11;32(5):1430-7. Epub 2010 Nov 11.

Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305-5233, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2010.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012961PMC
February 2011

Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms.

Endocrinology 2011 Jan 3;152(1):59-68. Epub 2010 Nov 3.

Department of Medicine/Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94350, USA.

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http://dx.doi.org/10.1210/en.2010-0576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033059PMC
January 2011

MicroRNA-26a is a novel regulator of vascular smooth muscle cell function.

J Cell Physiol 2011 Apr;226(4):1035-43

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1002/jcp.22422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108574PMC
April 2011

Three-dimensional hemodynamics in the human pulmonary arteries under resting and exercise conditions.

Ann Biomed Eng 2011 Jan 17;39(1):347-58. Epub 2010 Jul 17.

Department of Mechanical Engineering, Stanford University, Stanford, CA 94305-5431, USA.

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http://dx.doi.org/10.1007/s10439-010-0124-1DOI Listing
January 2011

New options with dabigatran etexilate in anticoagulant therapy.

Vasc Health Risk Manag 2010 May 25;6:339-49. Epub 2010 May 25.

Department of Cardiovascular Medicine, Stanford University - School of Medicine, Stanford, CA 94305-5406, USA.

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http://dx.doi.org/10.2147/vhrm.s8942DOI Listing
May 2010

Using pre-existing microarray datasets to increase experimental power: application to insulin resistance.

PLoS Comput Biol 2010 Mar 26;6(3):e1000718. Epub 2010 Mar 26.

Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1000718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845644PMC
March 2010

Modern role for clopidogrel in management of atrial fibrillation and stroke reduction.

Vasc Health Risk Manag 2010 Mar 3;6:95-103. Epub 2010 Mar 3.

Department of Cardiovascular Medicine, School of Medicine, Stanford University, CA 94305-5406, USA.

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http://dx.doi.org/10.2147/vhrm.s6104DOI Listing
March 2010

Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities.

Clin Chem 2010 Jan 5;56(1):111-20. Epub 2009 Nov 5.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305-5406, USA.

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January 2010

Apelin is necessary for the maintenance of insulin sensitivity.

Am J Physiol Endocrinol Metab 2010 Jan 27;298(1):E59-67. Epub 2009 Oct 27.

Div. of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Dr., Falk CVRC, Stanford, CA 94305-5406, USA.

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http://dx.doi.org/10.1152/ajpendo.00385.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806109PMC
January 2010

Differential intra-abdominal adipose tissue profiling in obese, insulin-resistant women.

Obes Surg 2009 Nov 27;19(11):1564-73. Epub 2009 Aug 27.

Division of Endocrinology, Department of Medicine, Stanford University Medical Center, 300 Pasteur Drive Rm S-025, Stanford, CA 94305, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181138PMC
November 2009