Publications by authors named "Philip Rosenthal"

100Publications

Keep Politics out of Funding Decisions for Medical Research and Public Health.

Am J Trop Med Hyg 2020 Sep;103(3):931-932

American Society of Tropical Medicine and Hygiene, Arlington, Virginia.

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http://dx.doi.org/10.4269/ajtmh.20-0850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470536PMC
September 2020

Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda.

Antimicrob Agents Chemother 2020 Sep 21;64(10). Epub 2020 Sep 21.

Department of Medicine, University of California, San Francisco, California, USA

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http://dx.doi.org/10.1128/AAC.00721-20DOI Listing
September 2020

Amalgamating Isatin/Indole/Nitroimidazole with 7-chloroquinolines via azide-alkyne cycloaddition: Synthesis, anti-plasmodial, and cytotoxic evaluation.

Chem Biol Drug Des 2020 Jun 8. Epub 2020 Jun 8.

Department of Chemistry, Guru Nanak Dev University, Amritsar, India.

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http://dx.doi.org/10.1111/cbdd.13738DOI Listing
June 2020

COVID-19: Shining the Light on Africa.

Am J Trop Med Hyg 2020 06;102(6):1145-1148

Scientific Program Chair, American Society of Tropical Medicine and Hygiene and UK Public Health Rapid Support Team, Public Health England/London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.4269/ajtmh.20-0380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253089PMC
June 2020

Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy.

ACS Infect Dis 2020 07 18;6(7):1827-1835. Epub 2020 May 18.

Department of Pharmaceutical Chemistry, University of California, San Francisco, 600 16th Street, San Francisco, California 94143, United States.

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http://dx.doi.org/10.1021/acsinfecdis.0c00064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363035PMC
July 2020

Hepatic Histology in Treatment-naïve Children With Chronic Hepatitis B Infection Living in the United States and Canada.

J Pediatr Gastroenterol Nutr 2020 Jul;71(1):99-105

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/MPG.0000000000002712DOI Listing
July 2020

The Importance of Diagnostic Testing during a Viral Pandemic: Early Lessons from Novel Coronavirus Disease (COVID-19).

Am J Trop Med Hyg 2020 05;102(5):915-916

Department of Medicine, University of California, San Francisco, California.

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http://dx.doi.org/10.4269/ajtmh.20-0216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204570PMC
May 2020

Are three drugs for malaria better than two?

Lancet 2020 04 11;395(10233):1316-1317. Epub 2020 Mar 11.

Department of Medicine, University of California, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30560-2DOI Listing
April 2020

Functionalized Naphthalimide-4-aminoquinoline Conjugates as Promising Antiplasmodials, with Mechanistic Insights.

ACS Med Chem Lett 2020 Feb 8;11(2):154-161. Epub 2020 Jan 8.

Department of Chemistry, Guru Nanak Dev University, Amritsar-143005, Punjab, India.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025377PMC
February 2020

Falcipain cysteine proteases of malaria parasites: An update.

Biochim Biophys Acta Proteins Proteom 2020 03 9;1868(3):140362. Epub 2020 Jan 9.

Dept. of Medicine, University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2020.140362DOI Listing
March 2020

Malaria parasites fine-tune mutations to resist drugs.

Nature 2019 12;576(7786):217-219

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http://dx.doi.org/10.1038/d41586-019-03587-0DOI Listing
December 2019

Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1,2,3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates.

Bioorg Med Chem Lett 2020 01 11;30(2):126810. Epub 2019 Nov 11.

Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.126810DOI Listing
January 2020

Be Careful What You Eat!

Am J Trop Med Hyg 2019 11;101(5):955-956

Department of Medicine, University of California, San Francisco, California.

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http://dx.doi.org/10.4269/ajtmh.19-0595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838582PMC
November 2019

Antimalarial drug resistance in Africa: the calm before the storm?

Lancet Infect Dis 2019 10 30;19(10):e338-e351. Epub 2019 Jul 30.

Department of Medicine, University of California, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30261-0DOI Listing
October 2019

The Diversity of the K13 Propeller Domain Did Not Increase after Implementation of Artemisinin-Based Combination Therapy in Uganda.

Antimicrob Agents Chemother 2019 10 23;63(10). Epub 2019 Sep 23.

Department of Medicine, University of California, San Francisco, San Francisco, California, USA

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http://dx.doi.org/10.1128/AAC.01234-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761569PMC
October 2019

A shorter course for anti-relapse therapy against vivax malaria.

Lancet 2019 09 18;394(10202):898-900. Epub 2019 Jul 18.

Department of Medicine, University of California, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(19)31605-8DOI Listing
September 2019

Reduced Exposure to Piperaquine, Compared to Adults, in Young Children Receiving Dihydroartemisinin-Piperaquine as Malaria Chemoprevention.

Clin Pharmacol Ther 2019 12 22;106(6):1310-1318. Epub 2019 Jul 22.

Department of Clinical Pharmacy, University of California San Francisco, San Francisco General Hospital, San Francisco, California, USA.

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http://dx.doi.org/10.1002/cpt.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851416PMC
December 2019

Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials.

J Med Chem 2019 06 22;62(11):5562-5578. Epub 2019 May 22.

School of Chemistry , Building F11, The University of Sydney , Sydney , New South Wales 2006 , Australia.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00504DOI Listing
June 2019

Substituted 1,3-dioxoisoindoline-4-aminoquinolines coupled via amide linkers: Synthesis, antiplasmodial and cytotoxic evaluation.

Bioorg Chem 2019 07 11;88:102912. Epub 2019 Apr 11.

Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.04.006DOI Listing
July 2019

Expanded Availability of Intravenous Artesunate for the Treatment of Severe Malaria in the United States.

Am J Trop Med Hyg 2019 06;100(6):1295-1296

Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.

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http://dx.doi.org/10.4269/ajtmh.19-0230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553912PMC
June 2019

Volume 100 of the .

Am J Trop Med Hyg 2019 01;100(1):3-4

Section Editor (former Editor-in-Chief).

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http://dx.doi.org/10.4269/ajtmh.18-0848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335895PMC
January 2019

Malaria: How Are We Doing and How Can We Do Better?

Am J Trop Med Hyg 2019 02;100(2):239-241

Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.4269/ajtmh.18-0997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367613PMC
February 2019

Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria.

Malar J 2018 Dec 18;17(1):476. Epub 2018 Dec 18.

Department of Pediatrics and Child Health, Makerere University, College of Health Sciences, Kampala, Uganda.

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http://dx.doi.org/10.1186/s12936-018-2630-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299589PMC
December 2018

Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda.

Antimicrob Agents Chemother 2019 03 26;63(3). Epub 2019 Feb 26.

Department of Medicine, University of California, San Francisco, San Francisco, California, USA

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http://dx.doi.org/10.1128/AAC.01818-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395896PMC
March 2019

Artemisinin Resistance in Eastern India.

Clin Infect Dis 2019 09;69(7):1153-1155

Department of Medicine, University of California, San Francisco.

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http://dx.doi.org/10.1093/cid/ciy1043DOI Listing
September 2019

Artemisinin Resistance Outside of Southeast Asia.

Am J Trop Med Hyg 2018 12;99(6):1357-1359

Department of Medicine, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.4269/ajtmh.18-0845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283499PMC
December 2018

Mass Drug Administration to Control and Eliminate Malaria in Africa: How Do We Best Utilize the Tools at Hand?

Clin Infect Dis 2019 07;69(2):287-289

Department of Medicine, University of California San Francisco.

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https://academic.oup.com/cid/advance-article/doi/10.1093/cid
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http://dx.doi.org/10.1093/cid/ciy871DOI Listing
July 2019

Advances in Pediatric Hepatology.

Authors:
Philip Rosenthal

Clin Liver Dis 2018 11;22(4):xi

Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, 550 16th Street, Mailcode 0136, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2018.08.001DOI Listing
November 2018

Has Rotavirus Vaccination Decreased the Prevalence of Biliary Atresia?

J Clin Gastroenterol 2019 09;53(8):e348-e351

Department of Pediatrics, University of California, San Francisco, CA.

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http://dx.doi.org/10.1097/MCG.0000000000001121DOI Listing
September 2019

Cysteine proteases in protozoan parasites.

PLoS Negl Trop Dis 2018 08 23;12(8):e0006512. Epub 2018 Aug 23.

Department of Medicine, University of California, San Francisco, San Francisco, California, United States of America.

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https://www.researchgate.net/profile/Jean_Bernatchez/publica
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http://dx.plos.org/10.1371/journal.pntd.0006512
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0006512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107107PMC
August 2018

Reconciling Conflicting Results From Pediatric Sepsis Studies: The Need for Context-Specific Sepsis Bundles.

Pediatr Crit Care Med 2018 06;19(6):594-595

Department of Pediatrics, University of California, San Francisco, CA Department of Medicine, University of California, San Francisco, CA.

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http://dx.doi.org/10.1097/PCC.0000000000001568DOI Listing
June 2018

A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients.

Clin Gastroenterol Hepatol 2018 11 30;16(11):1801-1810.e3. Epub 2018 Apr 30.

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.04.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197895PMC
November 2018

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease.

J Pediatr 2018 07 13;198:76-83.e2. Epub 2018 Apr 13.

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of California San Diego School of Medicine, La Jolla, CA; Department of Pediatrics, Division of Gastroenterology, Rady Children's Hospital, San Diego, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2018.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019181PMC
July 2018

Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability.

Eur J Med Chem 2018 Apr 19;149:69-78. Epub 2018 Feb 19.

Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.02.048DOI Listing
April 2018

Clinical consequences of submicroscopic malaria parasitaemia in Uganda.

Malar J 2018 Feb 5;17(1):67. Epub 2018 Feb 5.

Department of Medicine, University of California San Francisco, San Francisco, USA.

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http://dx.doi.org/10.1186/s12936-018-2221-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800031PMC
February 2018

Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010.

Environ Health 2018 02 1;17(1):12. Epub 2018 Feb 1.

Division of Pediatric Gastroenterology, Hepatology, and Nutrition; Department of Pediatrics, Benioff Children's Hospital San Francisco University of California San Francisco, Box 0136, 550 16th Street 5th Floor, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1186/s12940-018-0356-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796302PMC
February 2018

Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors.

J Pediatr 2018 02 7;193:119-127.e1. Epub 2017 Dec 7.

Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA; Department of Surgery, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1016/j.jpeds.2017.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794603PMC
February 2018

"The Way We Were" .

Am J Trop Med Hyg 2017 12;97(6):1955-1957

Department of Medicine University of California P.O. Box 0811 San Francisco, California 94946 E-mail:

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http://dx.doi.org/10.4269/ajtmh.17-0829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805082PMC
December 2017

Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation.

Eur J Med Chem 2018 Jan 16;143:150-156. Epub 2017 Nov 16.

Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, Punjab, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234173093
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http://dx.doi.org/10.1016/j.ejmech.2017.11.033DOI Listing
January 2018

Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study.

Am J Trop Med Hyg 2017 Nov 10;97(5):1513-1523. Epub 2017 Oct 10.

Clinical Epidemiology Unit, Department of Medicine, Makerere University-College of Health Sciences, Kampala, Uganda.

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.17-0056
Publisher Site
http://dx.doi.org/10.4269/ajtmh.17-0056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817743PMC
November 2017

Species Infecting Children Presenting with Malaria in Uganda.

Am J Trop Med Hyg 2017 Sep;97(3):753-757

Department of Medicine, University of California, San Francisco, San Francisco, California; 3Department of Medicine, Makerere University, Kampala, Uganda.

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http://dx.doi.org/10.4269/ajtmh.17-0345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590612PMC
September 2017