Publications by authors named "Philip Rosenstiel"

100Publications

The genomic basis of rapid adaptation to antibiotic combination therapy in Pseudomonas aeruginosa.

Mol Biol Evol 2020 Sep 15. Epub 2020 Sep 15.

Department of Evolutionary Ecology and Genetics, University of Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msaa233DOI Listing
September 2020

Reply.

Gastroenterology 2020 04 15;158(5):1512-1513. Epub 2020 Feb 15.

Institute of Clinical Molecular Biology and, Department of Internal Medicine I., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2020.02.021DOI Listing
April 2020

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.

Cell 2020 01;180(2):278-295.e23

Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978800PMC
January 2020

Autophagy of Intestinal Epithelial Cells Inhibits Colorectal Carcinogenesis Induced by Colibactin-Producing Escherichia coli in Apc Mice.

Gastroenterology 2020 04 7;158(5):1373-1388. Epub 2020 Jan 7.

M2iSH (Microbes, intestine, inflammation and Susceptibility of the Host), UMR 1071 Inserm, University of Clermont Auvergne, Clermont-Ferrand, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2019.12.026DOI Listing
April 2020

Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen .

Elife 2019 10 29;8. Epub 2019 Oct 29.

Department of Evolutionary Ecology and Genetics, University of Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.51481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881144PMC
October 2019

Autophagy: A Novel Mechanism Involved in the Anti-Inflammatory Abilities of Probiotics.

Cell Physiol Biochem 2019 ;53(5):774-793

University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Center for Infection and Immunity of Lille, Lille, France,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.33594/000000172DOI Listing
November 2019

A Phage Protein Aids Bacterial Symbionts in Eukaryote Immune Evasion.

Cell Host Microbe 2019 10 24;26(4):542-550.e5. Epub 2019 Sep 24.

GEOMAR Helmholtz Centre for Ocean Research Kiel, Marine Symbioses, 24105 Kiel, Germany; Christian-Albrechts-University of Kiel, 24105 Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chom.2019.08.019DOI Listing
October 2019

Experimental evolution of immunological specificity.

Proc Natl Acad Sci U S A 2019 10 23;116(41):20598-20604. Epub 2019 Sep 23.

Institute for Evolution and Biodiversity, University of Münster, 48149 Münster, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1904828116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789748PMC
October 2019

Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days.

J Antimicrob Chemother 2019 10;74(10):2916-2925

Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität zu Kiel, Am Botanischen Garten 1-9, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dkz297DOI Listing
October 2019

Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn's Disease.

Gastroenterology 2019 11 25;157(5):1310-1322.e13. Epub 2019 Jul 25.

Medical Clinic 1, Department of Medicine, University Hospital Erlangen, Friedrich-Alexander-University, Erlangen, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2019.07.031DOI Listing
November 2019

Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways.

Nat Commun 2019 07 22;10(1):3257. Epub 2019 Jul 22.

Zoological Institute, Christian-Albrechts University Kiel, Am Botanischen Garten 1-9, 24118, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-11136-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646324PMC
July 2019

aFold - using polynomial uncertainty modelling for differential gene expression estimation from RNA sequencing data.

BMC Genomics 2019 May 10;20(1):364. Epub 2019 May 10.

Evolutionary Ecology and Genetics, Zoological Institute, CAU Kiel, Am Botanischen Garten 9, 24118, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-019-5686-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509820PMC
May 2019

The genomic basis of Red Queen dynamics during rapid reciprocal host-pathogen coevolution.

Proc Natl Acad Sci U S A 2019 01 31;116(3):923-928. Epub 2018 Dec 31.

Department of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany;

View Article

Download full-text PDF

Source
http://www.pnas.org/lookup/doi/10.1073/pnas.1810402116
Publisher Site
http://dx.doi.org/10.1073/pnas.1810402116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338873PMC
January 2019

Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.

Proc Natl Acad Sci U S A 2018 09 12;115(39):9767-9772. Epub 2018 Sep 12.

Antibiotic Resistance Evolution Group, Max-Planck-Institute for Evolutionary Biology, 24306 Plön, Germany;

View Article

Download full-text PDF

Source
http://www.pnas.org/lookup/doi/10.1073/pnas.1810004115
Publisher Site
http://dx.doi.org/10.1073/pnas.1810004115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166819PMC
September 2018

Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1.

Eur J Hum Genet 2019 01 14;27(1):80-89. Epub 2018 Aug 14.

Department of Periodontology and Synoptic Dentistry, Institute for Dental and Craniofacial Sciences, Charité - University Medicine Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41431-018-0210-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303254PMC
January 2019

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.

Nature 2018 08 8;560(7719):489-493. Epub 2018 Aug 8.

Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41586-018-0395-5DOI Listing
August 2018

A Novel Eukaryotic Denitrification Pathway in Foraminifera.

Curr Biol 2018 08 2;28(16):2536-2543.e5. Epub 2018 Aug 2.

Institute of Microbiology, Kiel University, Am Botanischen Garten 11, Kiel 24118, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2018.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783311PMC
August 2018

Reply.

Gastroenterology 2018 06 8;154(8):2275-2276. Epub 2018 May 8.

Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2018.05.016DOI Listing
June 2018

Systems Medicine in Chronic Inflammatory Diseases.

Immunity 2018 04;48(4):608-613

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany; Department of MedicineI, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, 24105 Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2018.03.022DOI Listing
April 2018

DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.

Gastroenterology 2018 02 12;154(3):585-598. Epub 2017 Oct 12.

University Department of Paediatrics, University of Cambridge, UK; Department of Paediatric Gastroenterology, University of Cambridge and Addenbrooke's Hospital, Cambridge, UK; Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2017.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381389PMC
February 2018

Complete genome sequence of the nematicidal Bacillus thuringiensis MYBT18247.

J Biotechnol 2017 Oct 9;260:48-52. Epub 2017 Sep 9.

Department of Genomic and Applied Microbiology & Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, University of Goettingen, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbiotec.2017.09.003DOI Listing
October 2017

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases.

Gastroenterology 2017 12 19;153(6):1504-1516.e2. Epub 2017 Aug 19.

Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany; Institute of Clinical Molecular Biology, University of Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2017.08.028DOI Listing
December 2017

Regulated proteolysis as an element of ER stress and autophagy: Implications for intestinal inflammation.

Biochim Biophys Acta Mol Cell Res 2017 Nov 21;1864(11 Pt B):2183-2190. Epub 2017 Jul 21.

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2017.07.008DOI Listing
November 2017

Interpreting whole genome and exome sequencing data of individual gastric cancer samples.

BMC Genomics 2017 07 6;18(1):517. Epub 2017 Jul 6.

Institute of Pathology, Christian-Albrechts-University, Arnold-Heller-Str. 3, Haus 14, D-24105, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-017-3895-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501078PMC
July 2017

An improved filtering algorithm for big read datasets and its application to single-cell assembly.

BMC Bioinformatics 2017 Jul 3;18(1):324. Epub 2017 Jul 3.

Institute of Clinical Molecular Biology, Kiel University, Schittenhelmstr. 12, Kiel, 24105, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-017-1724-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496428PMC
July 2017

The resilience of the intestinal microbiota influences health and disease.

Nat Rev Microbiol 2017 Oct 19;15(10):630-638. Epub 2017 Jun 19.

Institute of Clinical Molecular Biology, Christian Albrechts University and University Hospital Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrmicro.2017.58DOI Listing
October 2017

Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4.

Cell Metab 2017 May 20;25(5):1063-1074.e3. Epub 2017 Apr 20.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8N 3Z5, Canada; Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON L8N 3Z5, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2017.03.021DOI Listing
May 2017

Highly potent host external immunity acts as a strong selective force enhancing rapid parasite virulence evolution.

Environ Microbiol 2017 05;19(5):2090-2100

Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität zu Kiel, Am Botanischen Garten 1-9, Kiel, 24118, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/1462-2920.13736
Publisher Site
http://dx.doi.org/10.1111/1462-2920.13736DOI Listing
May 2017

The Dark Age(ing) of the Inflammasome.

Immunity 2017 02;46(2):173-175

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Rosalind-Franklin Str. 12, D-24105 Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10747613173004
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2017.02.009DOI Listing
February 2017

Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer.

Biochim Biophys Acta Mol Cell Res 2017 May 8;1864(5):782-796. Epub 2017 Feb 8.

Department of Internal Medicine I, Laboratory of Molecular Gastroenterology & Hepatology, UKSH-Campus Kiel, Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2017.02.005DOI Listing
May 2017

Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection.

Gastroenterology 2017 03 17;152(4):799-811.e7. Epub 2016 Nov 17.

Department of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2016.11.010DOI Listing
March 2017

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects.

Immunity 2016 10 4;45(4):931-943. Epub 2016 Oct 4.

Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, Villejuif, 94805, France; Institut National de la Santé Et de la Recherche Medicale (INSERM), U1015, GRCC, Villejuif, 94805, France; University of Paris-Saclay, Kremlin Bicêtre, 94270, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, 94805, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2016.09.009DOI Listing
October 2016