Philip M Murphy

Philip M Murphy

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Philip M Murphy

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Abnormal Newborn Screen in a WHIM Syndrome Infant.

J Clin Immunol 2019 Sep 6. Epub 2019 Sep 6.

Walter Reed National Military Medical Center, 13101 Conover Dr., Silver Spring, Bethesda, MD, 20902, USA.

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http://dx.doi.org/10.1007/s10875-019-00686-5DOI Listing
September 2019

WHIM Syndrome: from Pathogenesis Towards Personalized Medicine and Cure.

J Clin Immunol 2019 Aug 16;39(6):532-556. Epub 2019 Jul 16.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10875-019-00665-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698215PMC
August 2019

Low-Level Parasite Persistence Drives Vasculitis and Myositis in Skeletal Muscle of Mice Chronically Infected with Trypanosoma cruzi.

Infect Immun 2019 06 21;87(6). Epub 2019 May 21.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/IAI.00081-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529661PMC
June 2019

IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to .

Elife 2019 Apr 16;8. Epub 2019 Apr 16.

Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, United States.

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http://dx.doi.org/10.7554/eLife.45501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504231PMC
April 2019

Plerixafor for the Treatment of WHIM Syndrome. Reply.

N Engl J Med 2019 04;380(16):e25

National Institute of Allergy and Infectious Diseases, Bethesda, MD

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http://dx.doi.org/10.1056/NEJMc1901646DOI Listing
April 2019

Hematopoietic chimerism and donor-specific skin allograft tolerance after non-genotoxic CD117 antibody-drug-conjugate conditioning in MHC-mismatched allotransplantation.

Nat Commun 2019 02 6;10(1):616. Epub 2019 Feb 6.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, 20892, MD, USA.

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http://dx.doi.org/10.1038/s41467-018-08202-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365540PMC
February 2019

WHIM syndrome: Immunopathogenesis, treatment and cure strategies.

Immunol Rev 2019 01;287(1):91-102

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://doi.wiley.com/10.1111/imr.12719
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http://dx.doi.org/10.1111/imr.12719DOI Listing
January 2019

Plerixafor for the Treatment of WHIM Syndrome.

N Engl J Med 2019 01;380(2):163-170

From the Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases (D.H.M., D.V., E.C., Q.L., P.M.M.), the Laboratories of Cellular Oncology (D.V.P., C.B.B.) and Pathology (S.P.), National Cancer Institute, the Department of Laboratory Medicine, Clinical Center (K.R.C.), the National Institute of Dental and Craniofacial Research (P.J.G.), and the National Institute on Deafness and Other Communication Disorders (D.A.B.), National Institutes of Health, and Kozloff and Trout MDs (H.H.T.), Bethesda, MD; the Infectious Diseases Unit and Primary Immunodeficiencies Unit, Hospital Dona Estefânia, Pediatric University Hospital (J.F.N.), and Centro de Imunodeficiências Primárias, Academic Medical Center of Lisbon (S.L.S.), Lisbon, Portugal; and the University of Chicago Medical Center, Chicago (E.A.B., E.M.L.).

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http://dx.doi.org/10.1056/NEJMoa1808575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425947PMC
January 2019

Case Report: Ocular toxoplasmosis in a WHIM syndrome immunodeficiency patient.

F1000Res 2019 2;8. Epub 2019 Jan 2.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.

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https://f1000research.com/articles/8-2/v2
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http://dx.doi.org/10.12688/f1000research.16825.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587139.2PMC
January 2019

Adaptive Immunodeficiency in WHIM Syndrome.

Int J Mol Sci 2018 Dec 20;20(1). Epub 2018 Dec 20.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.

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http://www.mdpi.com/1422-0067/20/1/3
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http://dx.doi.org/10.3390/ijms20010003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337672PMC
December 2018

Multisystem multitasking by CXCL12 and its receptors CXCR4 and ACKR3.

Cytokine 2018 09 15;109:2-10. Epub 2018 Feb 15.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.cyto.2017.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003845PMC
September 2018

Chemokine Subversion by Human Herpesviruses.

J Innate Immun 2018 30;10(5-6):465-478. Epub 2018 Aug 30.

Inflammation, Repair and Development Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United

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http://dx.doi.org/10.1159/000492161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289880PMC
August 2018

Mechanisms of Sustained Neutrophilia in Patient WHIM-09, Cured of WHIM Syndrome by Chromothripsis.

J Clin Immunol 2018 01 24;38(1):77-87. Epub 2017 Nov 24.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10875-017-0457-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743603PMC
January 2018

Chemokines encoded by herpesviruses.

J Leukoc Biol 2017 11 28;102(5):1199-1217. Epub 2017 Aug 28.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1189/jlb.4RU0417-145RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638632PMC
November 2017

Pathogenesis, diagnosis and therapeutic strategies in WHIM syndrome immunodeficiency.

Expert Opin Orphan Drugs 2017 25;5(10):813-825. Epub 2017 Sep 25.

Laboratory of Molecular Immunology, Bldg 10, Room 11N113, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.

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https://www.tandfonline.com/doi/full/10.1080/21678707.2017.1
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http://dx.doi.org/10.1080/21678707.2017.1375403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648064PMC
September 2017

Biochemical and biophysical characterization of cytokine-like protein 1 (CYTL1).

Cytokine 2017 08 4;96:238-246. Epub 2017 May 4.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, Rockville, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2017.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507608PMC
August 2017

Two glycosaminoglycan-binding domains of the mouse cytomegalovirus-encoded chemokine MCK-2 are critical for oligomerization of the full-length protein.

J Biol Chem 2017 06 21;292(23):9613-9626. Epub 2017 Apr 21.

From the Laboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, Maryland 20892

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http://dx.doi.org/10.1074/jbc.M117.785121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465486PMC
June 2017

WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

J Clin Immunol 2016 05 8;36(4):397-405. Epub 2016 Apr 8.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg. 10, Room 11 N107, Bethesda, MD, 20892-1886, USA.

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http://dx.doi.org/10.1007/s10875-016-0276-3DOI Listing
May 2016

Trypanosoma cruzi Causes Paralyzing Systemic Necrotizing Vasculitis Driven by Pathogen-Specific Type I Immunity in Mice.

Infect Immun 2016 Apr 24;84(4):1123-1136. Epub 2016 Mar 24.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/IAI.01497-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807493PMC
April 2016

Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity.

PLoS One 2015 3;10(6):e0127730. Epub 2015 Jun 3.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127730PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454597PMC
February 2016

The Macrophage-depleting Agent Clodronate Promotes Durable Hematopoietic Chimerism and Donor-specific Skin Allograft Tolerance in Mice.

Sci Rep 2016 Feb 26;6:22143. Epub 2016 Feb 26.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/srep22143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768260PMC
February 2016

Pre-treatment of allogeneic bone marrow recipients with the CXCR4 antagonist AMD3100 transiently enhances hematopoietic chimerism without promoting donor-specific skin allograft tolerance.

Transpl Immunol 2015 Oct 21;33(2):125-9. Epub 2015 Jul 21.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.trim.2015.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604054PMC
October 2015

Chromothriptic cure of WHIM syndrome: Implications for bone marrow transplantation.

Rare Dis 2015 11;3(1):e1073430. Epub 2015 Aug 11.

Laboratory of Molecular Immunology; National Institute of Allergy and Infectious Diseases; National Institutes of Health ; Bethesda, MD USA.

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http://dx.doi.org/10.1080/21675511.2015.1073430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588533PMC
October 2015

Characterization of chemokine and chemokine receptor expression during Pneumocystis infection in healthy and immunodeficient mice.

Microbes Infect 2015 Sep 5;17(9):638-50. Epub 2015 Jun 5.

Critical Care Medicine Department, NIH Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2015.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554965PMC
September 2015

CXCR4 antagonist AMD3100 redistributes leukocytes from primary immune organs to secondary immune organs, lung, and blood in mice.

Eur J Immunol 2015 Jun 24;45(6):1855-67. Epub 2015 Apr 24.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/eji.201445245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461468PMC
June 2015

Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.

Cardiovasc Res 2015 Jun 8;106(3):478-87. Epub 2015 Apr 8.

Molecular Signaling Section, Laboratory of Molecular Immunology (LMI), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA

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http://dx.doi.org/10.1093/cvr/cvv124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447808PMC
June 2015

Viral Chemokine Receptors.

Authors:
Philip M Murphy

Front Immunol 2015 5;6:281. Epub 2015 Jun 5.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, MD , USA.

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http://dx.doi.org/10.3389/fimmu.2015.00281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456963PMC
June 2015

Regulation of motor function and behavior by atypical chemokine receptor 1.

Behav Genet 2014 Sep 6;44(5):498-515. Epub 2014 Jul 6.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases (NIAID)/NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10519-014-9665-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790732PMC
September 2014

New nomenclature for atypical chemokine receptors.

Nat Immunol 2014 Mar;15(3):207-8

Institute for Research in Biomedicine, Bellinzona, Switzerland.

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http://dx.doi.org/10.1038/ni.2812DOI Listing
March 2014

Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis.

Cell Host Microbe 2013 Sep;14(3):318-28

Program in Barrier Immunity and Repair, Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.chom.2013.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806337PMC
September 2013

The major leukocyte chemotactic and activating factors in the mouse gut lumen are not N-formylpeptide receptor 1 agonists.

J Innate Immun 2013 20;5(1):2-14. Epub 2012 Jun 20.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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https://www.karger.com/Article/FullText/339572
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http://dx.doi.org/10.1159/000339572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769035PMC
July 2013

Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes.

Sci Rep 2012 8;2:786. Epub 2012 Nov 8.

Department of Spine Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China.

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http://dx.doi.org/10.1038/srep00786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493074PMC
April 2013

Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis.

J Clin Invest 2013 Apr;123(4):1694-704

Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1172/JCI65569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613917PMC
April 2013

Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.

Cardiovasc Res 2013 Mar 24;97(3):580-8. Epub 2012 Nov 24.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 10, Rm11N113, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/cvr/cvs349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567784PMC
March 2013

Regulation of atherogenesis by chemokines and chemokine receptors.

Arch Immunol Ther Exp (Warsz) 2013 Feb 7;61(1):1-14. Epub 2012 Dec 7.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00005-012-0202-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780344PMC
February 2013

Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis.

PLoS Pathog 2012 16;8(8):e1002865. Epub 2012 Aug 16.

Clinical Mycology Unit, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420964PMC
December 2012

The loss of RGS protein-Gα(i2) interactions results in markedly impaired mouse neutrophil trafficking to inflammatory sites.

Mol Cell Biol 2012 Nov 10;32(22):4561-71. Epub 2012 Sep 10.

B-Cell Molecular Immunology Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1128/MCB.00651-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486189PMC
November 2012

The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells.

J Biol Chem 2012 Nov 25;287(48):40779-92. Epub 2012 Sep 25.

Molecular Signaling Section, Laboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.411181
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http://dx.doi.org/10.1074/jbc.M112.411181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504790PMC
November 2012

Antimicrobial chemokines.

Front Immunol 2012 11;3:276. Epub 2012 Sep 11.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, MD, USA.

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http://journal.frontiersin.org/article/10.3389/fimmu.2012.00
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http://dx.doi.org/10.3389/fimmu.2012.00276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438526PMC
September 2012

Unexpected developments in immune organs in WHIM syndrome.

Blood 2012 Jun;119(24):5610-2

NIAID.

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http://dx.doi.org/10.1182/blood-2012-04-420752DOI Listing
June 2012

IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.

J Immunol 2012 Jan 12;188(2):649-60. Epub 2011 Dec 12.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1003845
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http://dx.doi.org/10.4049/jimmunol.1003845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253255PMC
January 2012

Characterization of Fpr-rs8, an atypical member of the mouse formyl peptide receptor gene family.

J Innate Immun 2011 17;3(5):519-29. Epub 2011 Jun 17.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1159/000327718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186714PMC
December 2011

Cyclophilin A cooperates with MIP-2 to augment neutrophil migration.

J Inflamm Res 2011 3;4:93-104. Epub 2011 Jun 3.

Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA.

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http://dx.doi.org/10.2147/JIR.S20733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218749PMC
November 2011

Reduced fear memory and anxiety-like behavior in mice lacking formylpeptide receptor 1.

Behav Genet 2011 Sep 12;41(5):724-33. Epub 2011 Apr 12.

Molecular Signalling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11N107, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s10519-011-9467-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143228PMC
September 2011

Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice.

Circ Res 2011 Aug 16;109(4):374-81. Epub 2011 Jun 16.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://circres.ahajournals.org/content/early/2011/06/16/CIRC
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http://circres.ahajournals.org/cgi/doi/10.1161/CIRCRESAHA.11
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http://dx.doi.org/10.1161/CIRCRESAHA.111.242578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151346PMC
August 2011

Regulation of atherogenesis by chemokine receptor CCR6.

Trends Cardiovasc Med 2011 Jul;21(5):140-4

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S105017381200080
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http://dx.doi.org/10.1016/j.tcm.2012.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384481PMC
July 2011

Organ-specific innate immune responses in a mouse model of invasive candidiasis.

J Innate Immun 2011 9;3(2):180-99. Epub 2010 Nov 9.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1159/000321157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072204PMC
June 2011

Chemokine control of West Nile virus infection.

Exp Cell Res 2011 Mar;317(5):569-74

Department of Microbiology, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, Box 1124, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.yexcr.2011.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050559PMC
March 2011

Host chemokines bind to Staphylococcus aureus and stimulate protein A release.

J Biol Chem 2011 Feb 7;286(7):5069-77. Epub 2010 Dec 7.

Molecular Signaling Section, Laboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M110.195180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037618PMC
February 2011

Chemokine receptor Ccr2 is critical for monocyte accumulation and survival in West Nile virus encephalitis.

J Immunol 2011 Jan 3;186(1):471-8. Epub 2010 Dec 3.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1003003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402345PMC
January 2011

Lack of glucose recycling between endoplasmic reticulum and cytoplasm underlies cellular dysfunction in glucose-6-phosphatase-beta-deficient neutrophils in a congenital neutropenia syndrome.

Blood 2010 Oct 24;116(15):2783-92. Epub 2010 May 24.

Section on Cellular Differentiation, Program on Developmental Endocrinology and Genetics, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, MD, USA.

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http://dx.doi.org/10.1182/blood-2009-12-258491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974586PMC
October 2010

Double duty for CCL21 in dendritic cell trafficking.

Authors:
Philip M Murphy

Immunity 2010 May;32(5):590-2

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.immuni.2010.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398834PMC
May 2010

CCR5 deficiency is a risk factor for early clinical manifestations of West Nile virus infection but not for viral transmission.

J Infect Dis 2010 Jan;201(2):178-85

Molecular Signaling Section, Laboratory of Molecular Immunology, Laboratory of Cellular and Molecular Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/6494
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http://dx.doi.org/10.1086/649426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934858PMC
January 2010

Atherogenic lipids induce high-density lipoprotein uptake and cholesterol efflux in human macrophages by up-regulating transmembrane chemokine CXCL16 without engaging CXCL16-dependent cell adhesion.

J Immunol 2009 Jun;182(12):7928-36

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.0804112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740747PMC
June 2009

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family.

Pharmacol Rev 2009 Jun 4;61(2):119-61. Epub 2009 Jun 4.

Department of Pharmacology, University of Illinois College of Medicine, 835 South Wolcott Avenue, M/C 868, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1124/pr.109.001578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745437PMC
June 2009

Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.

PLoS Pathog 2009 Feb 27;5(2):e1000321. Epub 2009 Feb 27.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1371/journal.ppat.1000321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642680PMC
February 2009

Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury.

J Immunol 2008 Dec;181(12):8670-6

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633769PMC
http://dx.doi.org/10.4049/jimmunol.181.12.8670DOI Listing
December 2008

SOCS3 negatively regulates the gp130-STAT3 pathway in mouse skin wound healing.

J Invest Dermatol 2008 Jul 10;128(7):1821-9. Epub 2008 Jan 10.

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/sj.jid.5701224DOI Listing
July 2008

Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour.

J Neurochem 2008 Jul 12;106(2):640-9. Epub 2008 Apr 12.

Departments of Physiology and Pharmacology and Clinical Sciences South Bristol, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05419.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726982PMC
July 2008

Roles of chemokines in renal ischemia/reperfusion injury.

Front Biosci 2008 May 1;13:4021-8. Epub 2008 May 1.

Department of Gastroenterology and Nephrology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.2741/2990DOI Listing
May 2008

Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function.

J Immunol 2008 Jan;180(1):569-79

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.180.1.569DOI Listing
January 2008

Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic.

J Infect Dis 2008 Jan;197(2):262-5

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1086/524691DOI Listing
January 2008

CCR1 deficiency increases susceptibility to fatal coronavirus infection of the central nervous system.

Viral Immunol 2007 Dec;20(4):599-608

Department of Molecular Biology and Biochemistry, Center for Immunology, University of California, Irvine, California 92697-3900, USA.

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http://dx.doi.org/10.1089/vim.2007.0056DOI Listing
December 2007

An oxidized lipid-peroxisome proliferator-activated receptor gamma-chemokine pathway in the regulation of macrophage-vascular smooth muscle cell adhesion.

Trends Cardiovasc Med 2007 Nov;17(8):269-74

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.tcm.2007.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149843PMC
November 2007

Chemokine regulation of atherosclerosis.

J Leukoc Biol 2007 Aug 29;82(2):226-36. Epub 2007 Mar 29.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1189/jlb.1206761DOI Listing
August 2007

Defective antitumor responses in CX3CR1-deficient mice.

Int J Cancer 2007 Jul;121(2):316-22

Thurston Arthritis Research Center and the Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1002/ijc.22660DOI Listing
July 2007

Atherogenic lipids induce adhesion of human coronary artery smooth muscle cells to macrophages by up-regulating chemokine CX3CL1 on smooth muscle cells in a TNFalpha-NFkappaB-dependent manner.

J Biol Chem 2007 Jun 23;282(26):19167-76. Epub 2007 Apr 23.

Molecular Signaling Section, Laboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M701642200DOI Listing
June 2007

Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97.

Infect Immun 2007 Mar 11;75(3):1144-53. Epub 2006 Dec 11.

Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1128/IAI.00869-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828551PMC
March 2007

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.

Blood 2007 Jan 31;109(1):78-84. Epub 2006 Aug 31.

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bldg 10-CRC 5-West Labs, Rm 5-3750, 10 Center Dr MSC 1456, Bethesda, MD 20892-1456, USA.

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http://dx.doi.org/10.1182/blood-2006-05-025296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1785067PMC
January 2007

Helix 8 of the viral chemokine receptor ORF74 directs chemokine binding.

J Biol Chem 2006 Nov 22;281(46):35327-35. Epub 2006 Sep 22.

Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M606877200DOI Listing
November 2006

Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.

J Biol Chem 2006 Sep 4;281(39):28794-801. Epub 2006 Aug 4.

Section on Cellular Differentiation, Heritable Disorders Branch, NICHD, Molecular Signaling Section, Laboratory of Molecular Immunology, NIAID, National Institutes of Health, Bethesda, Maryland 20892, USA.

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September 2006

Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury.

Am J Pathol 2006 Aug;169(2):372-87

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, Room 11N113, Bethesda, MD 20892-9000, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698788PMC
http://dx.doi.org/10.2353/ajpath.2006.060043DOI Listing
August 2006

Oxidized lipid-driven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells through a peroxisome proliferator-activated receptor gamma-dependent pathway.

Circulation 2006 Aug 14;114(8):807-19. Epub 2006 Aug 14.

Molecular Signaling SectionLaboratory of Molecular Immunology, National Institute ofAllergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. 20892, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.105.6
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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.602359DOI Listing
August 2006

CCR5: no longer a "good for nothing" gene--chemokine control of West Nile virus infection.

Trends Immunol 2006 Jul 5;27(7):308-12. Epub 2006 Jun 5.

Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.it.2006.05.007DOI Listing
July 2006

Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10.

Blood 2006 Jun 7;107(11):4240-3. Epub 2006 Feb 7.

Department of Cardiology, Rheinisch-Westfälische Technische Hochschule Aachen University, Germany.

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http://dx.doi.org/10.1182/blood-2005-09-3922DOI Listing
June 2006

Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression.

Int J Cancer 2006 Apr;118(8):1869-76

Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1002/ijc.21596DOI Listing
April 2006

Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines.

Mol Immunol 2006 Mar 15;43(8):1221-31. Epub 2005 Aug 15.

Leukocyte Biology and Section, Biomedical Sciences Division, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1016/j.molimm.2005.07.015DOI Listing
March 2006

CCR5 deficiency increases risk of symptomatic West Nile virus infection.

J Exp Med 2006 Jan 17;203(1):35-40. Epub 2006 Jan 17.

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.jem.org/lookup/doi/10.1084/jem.20051970
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118086PMC
January 2006

Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection.

J Exp Med 2005 Oct;202(8):1087-98

Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20042530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213214PMC
October 2005