Philip M Hansbro

Philip M Hansbro

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Philip M Hansbro

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Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases.

Chem Biol Interact 2019 Sep 2;310:108732. Epub 2019 Jul 2.

Centre for Inflammation, Centenary Institute, Royal Prince Alfred Hospital, Missenden Rd, Sydney, NSW, 2050, Australia; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.108732DOI Listing
September 2019

Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease.

Crit Rev Eukaryot Gene Expr 2018 ;28(2):125-127

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW 2305, Australia; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW, Australia.

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http://dx.doi.org/10.1615/CritRevEukaryotGeneExpr.2018022218DOI Listing
August 2019

Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases.

Chem Biol Interact 2019 Aug 25;308:206-215. Epub 2019 May 25.

School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara, 144411, Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.05.028DOI Listing
August 2019

Application of Chitosan and its Derivatives in Nanocarrier Based Pulmonary Drug Delivery Systems.

Pharm Nanotechnol 2017 ;5(4):243-249

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW2308, Australia.

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http://www.eurekaselect.com/154750/article
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http://dx.doi.org/10.2174/2211738505666170808095258DOI Listing
July 2019

Recent Developments in Alpha-Glucosidase Inhibitors for Management of Type-2 Diabetes: An Update.

Curr Pharm Des 2019 Jul 16. Epub 2019 Jul 16.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, . Australia.

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http://dx.doi.org/10.2174/1381612825666190717104547DOI Listing
July 2019

New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways.

Clin Sci (Lond) 2019 Jul 25;133(14):1663-1703. Epub 2019 Jul 25.

Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania 7248, Australia

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http://dx.doi.org/10.1042/CS20181009DOI Listing
July 2019

Microbiome-focused asthma management strategies.

Curr Opin Pharmacol 2019 Jul 26;46:143-149. Epub 2019 Jul 26.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute & University of Newcastle, Callaghan, NSW, Australia; Centre for inflammation, Centenary Institute, Sydney, and School of Life Sciences, University of Technology, Ultimo, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2019.06.003DOI Listing
July 2019

Epithelial-mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics.

Int J Chron Obstruct Pulmon Dis 2019 18;14:1603-1610. Epub 2019 Jul 18.

Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, TAS 7248, Australia.

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http://dx.doi.org/10.2147/COPD.S208428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645357PMC
July 2019

Targeting bacterial biofilms in pulmonary diseases in pediatric population.

Minerva Pediatr 2019 Jun 7;71(3):309-310. Epub 2018 Nov 7.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, Australia.

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https://www.minervamedica.it/index2.php?show=R15Y9999N00A181
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http://dx.doi.org/10.23736/S0026-4946.18.05256-8DOI Listing
June 2019

Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling.

Am J Respir Cell Mol Biol 2019 May;60(5):554-568

1 Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, The University of Sydney, Sydney, Australia.

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https://www.atsjournals.org/doi/10.1165/rcmb.2018-0215OC
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http://dx.doi.org/10.1165/rcmb.2018-0215OCDOI Listing
May 2019

Emerging therapeutic potential of group 2 innate lymphoid cells in acute kidney injury.

J Pathol 2019 May 5;248(1):9-15. Epub 2019 Mar 5.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1002/path.5242DOI Listing
May 2019

Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases.

Chem Biol Interact 2019 May 5;304:10-19. Epub 2019 Mar 5.

School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara, 144411, Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.02.021DOI Listing
May 2019

Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations.

Respir Res 2019 May 22;20(1):95. Epub 2019 May 22.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, New Lambton Heights, NSW, 2305, Australia.

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http://dx.doi.org/10.1186/s12931-019-1051-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530174PMC
May 2019

Understanding the Unfolded Protein Response in the Pathogenesis of Asthma.

Front Immunol 2018 6;9:175. Epub 2018 Feb 6.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2018.00175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810258PMC
April 2019

Lung development and emerging roles for type 2 immunity.

J Pathol 2019 Apr 16;247(5):686-696. Epub 2019 Jan 16.

Priority Research Center's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle and Hunter Medical Research Institute, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1002/path.5211DOI Listing
April 2019

Functional effects of the microbiota in chronic respiratory disease.

Lancet Respir Med 2019 Apr 8. Epub 2019 Apr 8.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, NSW, Australia; Centre for Inflammation, Centenary Institute, and University of Technology Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30510-1DOI Listing
April 2019

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury.

Front Immunol 2019 16;10:826. Epub 2019 Apr 16.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2019.00826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477147PMC
April 2019

TRPA1: A potential target for cold-induced airway disease?

Respirology 2019 Mar 13;24(3):193-194. Epub 2018 Dec 13.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, Newcastle, NSW, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13453
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http://dx.doi.org/10.1111/resp.13453DOI Listing
March 2019

Pulmonary group 2 innate lymphoid cells: surprises and challenges.

Mucosal Immunol 2019 03 21;12(2):299-311. Epub 2019 Jan 21.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle and Hunter Medical Research Institute, New Lambton Heights, NSW, 2305, Australia.

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http://dx.doi.org/10.1038/s41385-018-0130-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436699PMC
March 2019

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies.

Lab Invest 2019 02 19;99(2):150-157. Epub 2018 Nov 19.

Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, TAS, 7248, Australia.

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http://dx.doi.org/10.1038/s41374-018-0146-0DOI Listing
February 2019

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

Chem Biol Interact 2019 Feb 13;299:168-178. Epub 2018 Dec 13.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia; Faculty of Science, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia.

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http://dx.doi.org/10.1016/j.cbi.2018.12.009DOI Listing
February 2019

Mechanisms and Management of Asthma Exacerbations.

Am J Respir Crit Care Med 2019 Feb;199(4):423-432

1 Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1164/rccm.201810-1931CIDOI Listing
February 2019

TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.

BMC Pulm Med 2019 Feb 7;19(1):31. Epub 2019 Feb 7.

Experimental and Translational Respiratory Medicine Group, Level 2 East, Hunter Medical Research Institute, School of Medicine and Public Health, Faculty of Health, University of Newcastle, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1186/s12890-019-0786-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367767PMC
February 2019

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease.

J Leukoc Biol 2019 Jan 27;105(1):143-150. Epub 2018 Sep 27.

Priority Research Centres for Healthy Lungs and GrowUpWell, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1002/JLB.3AB0518-178RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487813PMC
January 2019

Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK.

Am J Physiol Lung Cell Mol Physiol 2019 Jan 8;316(1):L157-L174. Epub 2018 Nov 8.

Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, The University of Sydney , Sydney, New South Wales , Australia.

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https://www.physiology.org/doi/10.1152/ajplung.00306.2018
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http://dx.doi.org/10.1152/ajplung.00306.2018DOI Listing
January 2019

Novel drug delivery approaches in treating pulmonary fibrosis.

Panminerva Med 2018 Dec 26;60(4):238-240. Epub 2018 Feb 26.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, Australia.

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http://dx.doi.org/10.23736/S0031-0808.18.03428-6DOI Listing
December 2018

The role of environmental exposure to non-cigarette smoke in lung disease.

Clin Transl Med 2018 Dec 5;7(1):39. Epub 2018 Dec 5.

School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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http://dx.doi.org/10.1186/s40169-018-0217-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279673PMC
December 2018

Targeting microRNAs using nanotechnology in pulmonary diseases.

Panminerva Med 2018 Dec;60(4):230-231

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, Australia.

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http://dx.doi.org/10.23736/S0031-0808.18.03459-6DOI Listing
December 2018

Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches.

Biomed Pharmacother 2018 Nov 29;107:1218-1229. Epub 2018 Aug 29.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S07533322183380
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http://dx.doi.org/10.1016/j.biopha.2018.08.101DOI Listing
November 2018

Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD.

Respir Res 2018 Nov 3;19(1):211. Epub 2018 Nov 3.

Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, The University of Sydney, Sydney, Australia.

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https://respiratory-research.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12931-018-0919-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215599PMC
November 2018

Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.

Drugs 2018 Nov;78(16):1717-1740

Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Locked Bag-1322, Newnham Drive, Launceston, TAS, 7248, Australia.

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http://link.springer.com/10.1007/s40265-018-1001-8
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http://dx.doi.org/10.1007/s40265-018-1001-8DOI Listing
November 2018

Role of Oxidative Stress in the Pathology and Management of Human Tuberculosis.

Oxid Med Cell Longev 2018 11;2018:7695364. Epub 2018 Oct 11.

School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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https://www.hindawi.com/journals/omcl/2018/7695364/
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http://dx.doi.org/10.1155/2018/7695364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201333PMC
November 2018

Functional relevance of SATB1 in immune regulation and tumorigenesis.

Biomed Pharmacother 2018 Aug 14;104:87-93. Epub 2018 May 14.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.05.045DOI Listing
August 2018

Microbiome as therapeutics in vesicular delivery.

Biomed Pharmacother 2018 Aug 29;104:738-741. Epub 2018 May 29.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, Australia; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW 2305, Australia.

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http://dx.doi.org/10.1016/j.biopha.2018.05.099DOI Listing
August 2018

Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics.

Respir Res 2018 08 2;19(1):145. Epub 2018 Aug 2.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, HMRI building, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1186/s12931-018-0851-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090696PMC
August 2018

IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis.

Am J Pathol 2018 07 22;188(7):1625-1639. Epub 2018 Apr 22.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales; Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia; Priority Research Centre for Digestive Health and Neurogastroenterology, University of Newcastle, Callaghan, New South Wales. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.03.016DOI Listing
July 2018

Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells.

Am J Physiol Lung Cell Mol Physiol 2018 06 25;314(6):L922-L935. Epub 2018 Jan 25.

Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, University of Sydney , Sydney , Australia.

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https://www.physiology.org/doi/10.1152/ajplung.00438.2017
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http://dx.doi.org/10.1152/ajplung.00438.2017DOI Listing
June 2018

Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches.

Pharmacol Ther 2018 05 27;185:155-169. Epub 2017 Dec 27.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, New South Wales, Australia; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1016/j.pharmthera.2017.12.009DOI Listing
May 2018

Immunological axis of curcumin-loaded vesicular drug delivery systems.

Future Med Chem 2018 04 5;10(8):839-844. Epub 2018 Apr 5.

School of Biomedical Sciences & Pharmacy, University of Newcastle, Newcastle, NSW 2308, Australia.

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http://dx.doi.org/10.4155/fmc-2017-0245DOI Listing
April 2018

Tumor suppressor role of miR-503.

Panminerva Med 2018 Mar 22;60(1):17-24. Epub 2017 Nov 22.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, Australia -

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http://dx.doi.org/10.23736/S0031-0808.17.03386-9DOI Listing
March 2018

Advancements in nano drug delivery systems: a challenge for biofilms in respiratory diseases.

Panminerva Med 2018 03 25;60(1):35-36. Epub 2018 Jan 25.

Department of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.

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http://dx.doi.org/10.23736/S0031-0808.18.03402-XDOI Listing
March 2018

Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease.

Am J Physiol Lung Cell Mol Physiol 2018 02 12;314(2):L298-L317. Epub 2017 Oct 12.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute and University of Newcastle, Callaghan, New South Wales , Australia.

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http://dx.doi.org/10.1152/ajplung.00154.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866502PMC
February 2018

Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?

Eur Respir Rev 2017 Dec 25;26(146). Epub 2017 Oct 25.

Experimental Studies, National Heart and Lung Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.1183/16000617.0040-2017DOI Listing
December 2017

Upregulated pneumococcal adhesion molecule (platelet-activating factor receptor) may predispose COPD patients to community-acquired pneumonia.

Int J Chron Obstruct Pulmon Dis 2017 24;12:3111-3113. Epub 2017 Oct 24.

School of Medicine, University of Tasmania, Hobart, TAS, Australia.

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http://dx.doi.org/10.2147/COPD.S151142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661495PMC
November 2017

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.

PLoS One 2017 1;12(9):e0184260. Epub 2017 Sep 1.

Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184260PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580912PMC
October 2017

Potential Mechanisms of Microbial Pathogens in Idiopathic Interstitial Lung Disease.

Chest 2017 10;152(4):899-900

Breathe Well Centre of Research Excellence for Chronic Respiratory Disease and Lung Ageing, University of Tasmania, Launceston, Australia.

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http://dx.doi.org/10.1016/j.chest.2017.05.024DOI Listing
October 2017

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD).

Sci Rep 2017 10 17;7(1):13392. Epub 2017 Oct 17.

NHMRC Centre for Research Excellence for Chronic Respiratory Disease, School of Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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http://dx.doi.org/10.1038/s41598-017-13888-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645352PMC
October 2017

TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD.

PLoS One 2016 16;11(6):e0156402. Epub 2016 Jun 16.

The Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156402PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911048PMC
July 2017

Role of iron in the pathogenesis of respiratory disease.

Int J Biochem Cell Biol 2017 07 7;88:181-195. Epub 2017 May 7.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan NSW 2308, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.05.003DOI Listing
July 2017

Modeling T 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma.

Immunol Rev 2017 07;278(1):20-40

Paediatric Respiratory and Sleep Medicine Unit, Priority Research Centre for Healthy Lungs and GrowUpWell, University of Newcastle and Hunter Medical Research Institute, John Hunter Children's Hospital, Newcastle, NSW, Australia.

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http://doi.wiley.com/10.1111/imr.12549
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http://dx.doi.org/10.1111/imr.12549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492958PMC
July 2017

Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma.

Immunol Rev 2017 07;278(1):41-62

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, NSW, Australia.

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http://dx.doi.org/10.1111/imr.12543DOI Listing
July 2017

Inflammasomes in the lung.

Mol Immunol 2017 06 24;86:44-55. Epub 2017 Jan 24.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.01.014DOI Listing
June 2017

Steroid resistance and concomitant respiratory infections: A challenging battle in pulmonary clinic.

EXCLI J 2017 29;16:981-985. Epub 2017 Jun 29.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW2308, Australia.

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http://dx.doi.org/10.17179/excli2017-425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579404PMC
June 2017

The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD.

Respirology 2017 05 25;22(4):634-650. Epub 2017 Mar 25.

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.

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http://dx.doi.org/10.1111/resp.13032DOI Listing
May 2017

Attenuating immune pathology using a microbial-based intervention in a mouse model of cigarette smoke-induced lung inflammation.

Respir Res 2017 05 15;18(1):92. Epub 2017 May 15.

Department of Medicine, Division of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada, V6H 3Z6.

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http://dx.doi.org/10.1186/s12931-017-0577-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433159PMC
May 2017

Toll-like receptors in COPD.

Eur Respir J 2017 05 23;49(5). Epub 2017 May 23.

Division of Innate Immunity, Dept of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1183/13993003.00739-2017DOI Listing
May 2017

MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD.

JCI Insight 2017 04 6;2(7):e90443. Epub 2017 Apr 6.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1172/jci.insight.90443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374076PMC
April 2017

Experimental Arthritis Is Dependent on Mouse Mast Cell Protease-5.

J Biol Chem 2017 03 13;292(13):5392-5404. Epub 2017 Feb 13.

From the Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales 2217, Australia.

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http://dx.doi.org/10.1074/jbc.M116.773416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392683PMC
March 2017

Microbiome effects on immunity, health and disease in the lung.

Clin Transl Immunology 2017 Mar 10;6(3):e133. Epub 2017 Mar 10.

Priority Research Centre for Healthy Lungs and Hunter Medical Research Institute, The University of Newcastle, Newcastle, NSW, Australia.

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http://doi.wiley.com/10.1038/cti.2017.6
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http://dx.doi.org/10.1038/cti.2017.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382435PMC
March 2017

MicroRNAs as therapeutics for future drug delivery systems in treatment of lung diseases.

Drug Deliv Transl Res 2017 02;7(1):168-178

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW, 2305, Australia.

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http://dx.doi.org/10.1007/s13346-016-0343-6DOI Listing
February 2017

Whether a novel drug delivery system can overcome the problem of biofilms in respiratory diseases?

Drug Deliv Transl Res 2017 02;7(1):179-187

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW, 2305, Australia.

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http://dx.doi.org/10.1007/s13346-016-0349-0DOI Listing
February 2017

Microbiomes in respiratory health and disease: An Asia-Pacific perspective.

Respirology 2017 02;22(2):240-250

Priority Research Centre for Healthy Lungs, University of Newcastle and Hunter Medical Research Institute, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1111/resp.12971DOI Listing
February 2017

MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2017 01;195(1):43-56

1 Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1164/rccm.201506-1182OCDOI Listing
January 2017

Animal models of COPD: What do they tell us?

Respirology 2017 01 12;22(1):21-32. Epub 2016 Oct 12.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, Newcastle, New South Wales, Australia, London, UK.

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http://dx.doi.org/10.1111/resp.12908DOI Listing
January 2017

Emerging pathogenic links between microbiota and the gut-lung axis.

Nat Rev Microbiol 2017 01 3;15(1):55-63. Epub 2016 Oct 3.

Priority Research Centre for Healthy Lungs, University of Newcastle and Hunter Medical Research Institute, Newcastle, New South Wales 2305, Australia.

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http://www.nature.com/articles/nrmicro.2016.142
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http://dx.doi.org/10.1038/nrmicro.2016.142DOI Listing
January 2017

TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection.

Am J Physiol Lung Cell Mol Physiol 2017 01 11;312(1):L89-L99. Epub 2016 Nov 11.

Experimental and Translational Respiratory Medicine Group, University of Newcastle and Hunter Medical Research Institute, Newcastle, Australia;

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http://dx.doi.org/10.1152/ajplung.00200.2016DOI Listing
January 2017

TRAIL deficiency and PP2A activation with salmeterol ameliorates egg allergen-driven eosinophilic esophagitis.

Am J Physiol Gastrointest Liver Physiol 2016 12 13;311(6):G998-G1008. Epub 2016 Oct 13.

The Priority Research Centre GrowUpWell, Newcastle, Australia.

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http://dx.doi.org/10.1152/ajpgi.00151.2016DOI Listing
December 2016

A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro.

Thorax 2016 Nov 10;71(11):1039-1049. Epub 2016 Jun 10.

Woolcock Institute of Medical Research, The University of Sydney, Sydney, New South Wales, Australia Centre for Health Technologies and Molecular Biosciences, School of Life Sciences, University of Technology Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1136/thoraxjnl-2015-207781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099217PMC
November 2016

A Novel, Molybdenum-Containing Methionine Sulfoxide Reductase Supports Survival of in an Model of Infection.

Front Microbiol 2016 14;7:1743. Epub 2016 Nov 14.

Centre for Metals in Biology/Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia QLD, Australia.

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http://dx.doi.org/10.3389/fmicb.2016.01743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122715PMC
November 2016

TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators.

Int J Biochem Cell Biol 2016 09 28;78:279-287. Epub 2016 Jul 28.

Woolcock Emphysema Centre, Woolcock Institute of Medical Research, University of Sydney, NSW, Australia; School of Life Sciences, Faculty of Science, University of Technology Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.07.030DOI Listing
September 2016

The genetic and epigenetic landscapes of the epithelium in asthma.

Respir Res 2016 Sep 22;17(1):119. Epub 2016 Sep 22.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, HMRI building, The University of Newcastle, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1186/s12931-016-0434-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034566PMC
September 2016

Elucidating novel disease mechanisms in severe asthma.

Clin Transl Immunology 2016 Jul 15;5(7):e91. Epub 2016 Jul 15.

Priority Research Centre for Healthy Lungs and Hunter Medical Research Institute, University of Newcastle , Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1038/cti.2016.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973321PMC
July 2016