Philip M Hansbro

Philip M Hansbro

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Philip M Hansbro

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Sputum macrophage diversity and activation in asthma: role of severity and inflammatory phenotype.

Allergy 2020 Aug 1. Epub 2020 Aug 1.

National Heart & Lung Institute, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1111/all.14535DOI Listing
August 2020

Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective.

Chem Biol Interact 2020 Jul 4;325:109125. Epub 2020 May 4.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia; School of Pharmaceutical Sciences, Shoolini University, Bajhol, Sultanpur, Solan, Himachal Pradesh, 173229, India; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2020.109125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196551PMC
July 2020

Emerging therapeutic targets and preclinical models for severe asthma.

Expert Opin Ther Targets 2020 Jul 7:1-13. Epub 2020 Jul 7.

Centre for Inflammation, Centenary Institute and University of Technology Sydney , Sydney, Australia.

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http://dx.doi.org/10.1080/14728222.2020.1786535DOI Listing
July 2020

SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis.

Respir Res 2020 Jul 14;21(1):182. Epub 2020 Jul 14.

Centre for Inflammation, Centenary Institute, Camperdown, NSW, 2050, Australia.

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http://dx.doi.org/10.1186/s12931-020-01445-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359430PMC
July 2020

Targeting Cancer using Curcumin Encapsulated Vesicular Drug Delivery Systems.

Curr Pharm Des 2020 Jul 28. Epub 2020 Jul 28.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007. Australia.

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http://dx.doi.org/10.2174/1381612826666200728151610DOI Listing
July 2020

miRNA nanotherapeutics: potential and challenges in respiratory disorders.

Future Med Chem 2020 Jun 9;12(11):987-990. Epub 2020 Apr 9.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW, 2007, Australia.

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http://dx.doi.org/10.4155/fmc-2020-0066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351087PMC
June 2020

infection differentially alters smooth muscle function in mouse uterine horn and cervix.

Am J Physiol Endocrinol Metab 2020 Jun 21;318(6):E981-E994. Epub 2020 Apr 21.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia.

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http://dx.doi.org/10.1152/ajpendo.00513.2019DOI Listing
June 2020

Acetate protects against intestinal ischemia-reperfusion injury independent of its cognate free fatty acid 2 receptor.

FASEB J 2020 Jun 17. Epub 2020 Jun 17.

School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1096/fj.202000960RDOI Listing
June 2020

Critical role for iron accumulation in the pathogenesis of fibrotic lung disease.

J Pathol 2020 May 30;251(1):49-62. Epub 2020 Mar 30.

Priority Research Centre for Healthy Lungs and School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, University of Newcastle, Newcastle, Australia.

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http://dx.doi.org/10.1002/path.5401DOI Listing
May 2020

Role of the mucins in pathogenesis of COPD: implications for therapy.

Expert Rev Respir Med 2020 May 19;14(5):465-483. Epub 2020 Mar 19.

Pneumologia, Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università di Messina, Messina, Italy.

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http://dx.doi.org/10.1080/17476348.2020.1739525DOI Listing
May 2020

Incipient need of targeting airway remodeling using advanced drug delivery in chronic respiratory diseases.

Future Med Chem 2020 May 30;12(10):873-875. Epub 2020 Apr 30.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia.

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http://dx.doi.org/10.4155/fmc-2020-0091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319495PMC
May 2020

Host-microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease.

Eur Respir J 2020 May 19. Epub 2020 May 19.

Early Life Origins of Chronic Lung Diseases, Research Center Borstel, Leibniz Lung Center, Member of the German Center for Lung Research (DZL), Borstel, Germany

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http://dx.doi.org/10.1183/13993003.02320-2019DOI Listing
May 2020

Recent Developments in Alpha-Glucosidase Inhibitors for Management of Type-2 Diabetes: An Update.

Curr Pharm Des 2019 ;25(23):2510-2525

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, Australia.

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http://dx.doi.org/10.2174/1381612825666190717104547DOI Listing
April 2020

Recent advances in experimental animal models of lung cancer.

Future Med Chem 2020 Apr 16;12(7):567-570. Epub 2020 Mar 16.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Chippendale, NSW 2007, Australia.

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http://dx.doi.org/10.4155/fmc-2019-0338DOI Listing
April 2020

MicroRNAs as Biomarker for Breast Cancer

Endocr Metab Immune Disord Drug Targets 2020 04 28. Epub 2020 Apr 28.

Department of Biochemistry, Central University of Haryana, Jant-Pali, Mahendergarh District, 123031, Haryana, India

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http://dx.doi.org/10.2174/1871530320666200428113051DOI Listing
April 2020

Elastin is a key factor of tumor development in colorectal cancer.

BMC Cancer 2020 Mar 14;20(1):217. Epub 2020 Mar 14.

School of Life Sciences, Faculty of Science, University of Technology Sydney, Ultimo, New South Wales, Australia.

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http://dx.doi.org/10.1186/s12885-020-6686-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071655PMC
March 2020

Epithelial-mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics.

Int J Chron Obstruct Pulmon Dis 2019 18;14:1603-1610. Epub 2019 Jul 18.

Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, TAS 7248, Australia.

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http://dx.doi.org/10.2147/COPD.S208428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645357PMC
February 2020

IL-33 in Chronic Respiratory Disease: From Preclinical to Clinical Studies.

ACS Pharmacol Transl Sci 2020 Feb 20;3(1):56-62. Epub 2019 Dec 20.

Centre for Inflammation, Centenary Institute and University of Technology Sydney, Faculty of Science, Sydney, New South Wales 2050, Australia.

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http://dx.doi.org/10.1021/acsptsci.9b00099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088894PMC
February 2020

Lipopolysaccharide induces steroid-resistant exacerbations in a mouse model of allergic airway disease collectively through IL-13 and pulmonary macrophage activation.

Clin Exp Allergy 2020 01 18;50(1):82-94. Epub 2019 Oct 18.

Priority Research Centre for Healthy Lungs, Department of Microbiology and Immunology, School of Biomedical Sciences & Pharmacy, Faculty of Health and Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1111/cea.13505DOI Listing
January 2020

Assessment of evidence for or against contributions of Chlamydia pneumoniae infections to Alzheimer's disease etiology.

Brain Behav Immun 2020 01 15;83:22-32. Epub 2019 Oct 15.

School of Biomedical Sciences and Pharmacy, University Drive, University of Newcastle, Callaghan NSW 2308, Australia.

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http://dx.doi.org/10.1016/j.bbi.2019.10.014DOI Listing
January 2020

Hypoxia-inducible factor and bacterial infections in chronic obstructive pulmonary disease.

Respirology 2020 01 30;25(1):53-63. Epub 2019 Oct 30.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Newcastle, NSW, Australia.

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http://dx.doi.org/10.1111/resp.13722DOI Listing
January 2020

Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.

J Med Chem 2019 11 16;62(21):9874-9889. Epub 2019 Oct 16.

Pharmaxis Ltd , 20 Rodborough Road, Frenchs Forest , Sydney , New South Wales 2086 , Australia.

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http://dx.doi.org/10.1021/acs.jmedchem.9b01283DOI Listing
November 2019

Functional effects of the microbiota in chronic respiratory disease.

Lancet Respir Med 2019 10 8;7(10):907-920. Epub 2019 Apr 8.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and The University of Newcastle, Newcastle, NSW, Australia; Centre for Inflammation, Centenary Institute, and University of Technology Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30510-1DOI Listing
October 2019

COPD and the gut-lung axis: the therapeutic potential of fibre.

J Thorac Dis 2019 Oct;11(Suppl 17):S2173-S2180

UQ Thoracic Research Centre, Faculty of Medicine, The University of Queensland, Chermside, Brisbane, Australia.

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http://dx.doi.org/10.21037/jtd.2019.10.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831926PMC
October 2019

Enhancing tristetraprolin activity reduces the severity of cigarette smoke-induced experimental chronic obstructive pulmonary disease.

Clin Transl Immunology 2019 28;8(10):e01084. Epub 2019 Oct 28.

Priority Research Centres for Healthy Lungs, Grow Up Well and Cancer Research, Innovation and Translation Hunter Medical Research Institute University of Newcastle NSW Australia.

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http://dx.doi.org/10.1002/cti2.1084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946917PMC
October 2019

Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases.

Chem Biol Interact 2019 Sep 2;310:108732. Epub 2019 Jul 2.

Centre for Inflammation, Centenary Institute, Royal Prince Alfred Hospital, Missenden Rd, Sydney, NSW, 2050, Australia; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.108732DOI Listing
September 2019

Cellular mechanisms underlying steroid-resistant asthma.

Eur Respir Rev 2019 Sep 21;28(153). Epub 2019 Oct 21.

Centre for Inflammation, Centenary Institute, Sydney, Australia.

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http://dx.doi.org/10.1183/16000617.0096-2019DOI Listing
September 2019

Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease.

Crit Rev Eukaryot Gene Expr 2018 ;28(2):125-127

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW 2305, Australia; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW, Australia.

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http://dx.doi.org/10.1615/CritRevEukaryotGeneExpr.2018022218DOI Listing
August 2019

Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases.

Chem Biol Interact 2019 Aug 25;308:206-215. Epub 2019 May 25.

School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara, 144411, Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094617PMC
August 2019

Application of Chitosan and its Derivatives in Nanocarrier Based Pulmonary Drug Delivery Systems.

Pharm Nanotechnol 2017 ;5(4):243-249

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW2308, Australia.

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http://www.eurekaselect.com/154750/article
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http://dx.doi.org/10.2174/2211738505666170808095258DOI Listing
July 2019

New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways.

Clin Sci (Lond) 2019 07 25;133(14):1663-1703. Epub 2019 Jul 25.

Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania 7248, Australia

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http://dx.doi.org/10.1042/CS20181009DOI Listing
July 2019

Targeting bacterial biofilms in pulmonary diseases in pediatric population.

Minerva Pediatr 2019 Jun 7;71(3):309-310. Epub 2018 Nov 7.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, Australia.

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https://www.minervamedica.it/index2.php?show=R15Y9999N00A181
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http://dx.doi.org/10.23736/S0026-4946.18.05256-8DOI Listing
June 2019

Microbiome-focused asthma management strategies.

Curr Opin Pharmacol 2019 06 26;46:143-149. Epub 2019 Jul 26.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute & University of Newcastle, Callaghan, NSW, Australia; Centre for inflammation, Centenary Institute, Sydney, and School of Life Sciences, University of Technology, Ultimo, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2019.06.003DOI Listing
June 2019

Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling.

Am J Respir Cell Mol Biol 2019 05;60(5):554-568

1 Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, The University of Sydney, Sydney, Australia.

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https://www.atsjournals.org/doi/10.1165/rcmb.2018-0215OC
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http://dx.doi.org/10.1165/rcmb.2018-0215OCDOI Listing
May 2019

Emerging therapeutic potential of group 2 innate lymphoid cells in acute kidney injury.

J Pathol 2019 05 5;248(1):9-15. Epub 2019 Mar 5.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.1002/path.5242DOI Listing
May 2019

Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases.

Chem Biol Interact 2019 May 5;304:10-19. Epub 2019 Mar 5.

School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara, 144411, Punjab, India. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.02.021DOI Listing
May 2019

Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations.

Respir Res 2019 May 22;20(1):95. Epub 2019 May 22.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, New Lambton Heights, NSW, 2305, Australia.

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http://dx.doi.org/10.1186/s12931-019-1051-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530174PMC
May 2019

Understanding the Unfolded Protein Response in the Pathogenesis of Asthma.

Front Immunol 2018 6;9:175. Epub 2018 Feb 6.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2018.00175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810258PMC
April 2019

Lung development and emerging roles for type 2 immunity.

J Pathol 2019 04 16;247(5):686-696. Epub 2019 Jan 16.

Priority Research Center's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle and Hunter Medical Research Institute, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1002/path.5211DOI Listing
April 2019

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury.

Front Immunol 2019 16;10:826. Epub 2019 Apr 16.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2019.00826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477147PMC
April 2019

TRPA1: A potential target for cold-induced airway disease?

Respirology 2019 03 13;24(3):193-194. Epub 2018 Dec 13.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, Newcastle, NSW, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13453
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http://dx.doi.org/10.1111/resp.13453DOI Listing
March 2019

Pulmonary group 2 innate lymphoid cells: surprises and challenges.

Mucosal Immunol 2019 03 21;12(2):299-311. Epub 2019 Jan 21.

Priority Research Centre's GrowUpWell and Healthy Lungs, School of Biomedical Sciences and Pharmacy, The University of Newcastle and Hunter Medical Research Institute, New Lambton Heights, NSW, 2305, Australia.

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http://dx.doi.org/10.1038/s41385-018-0130-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436699PMC
March 2019

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies.

Lab Invest 2019 02 19;99(2):150-157. Epub 2018 Nov 19.

Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, TAS, 7248, Australia.

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http://dx.doi.org/10.1038/s41374-018-0146-0DOI Listing
February 2019

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

Chem Biol Interact 2019 Feb 13;299:168-178. Epub 2018 Dec 13.

Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, 2308, Australia; Faculty of Science, University of Technology Sydney, Ultimo, NSW, 2007, Australia; Centre for Inflammation, Centenary Institute, Sydney, NSW, 2050, Australia.

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http://dx.doi.org/10.1016/j.cbi.2018.12.009DOI Listing
February 2019

Mechanisms and Management of Asthma Exacerbations.

Am J Respir Crit Care Med 2019 02;199(4):423-432

1 Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1164/rccm.201810-1931CIDOI Listing
February 2019

TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.

BMC Pulm Med 2019 Feb 7;19(1):31. Epub 2019 Feb 7.

Experimental and Translational Respiratory Medicine Group, Level 2 East, Hunter Medical Research Institute, School of Medicine and Public Health, Faculty of Health, University of Newcastle, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1186/s12890-019-0786-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367767PMC
February 2019

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease.

J Leukoc Biol 2019 01 27;105(1):143-150. Epub 2018 Sep 27.

Priority Research Centres for Healthy Lungs and GrowUpWell, Hunter Medical Research Institute and The University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1002/JLB.3AB0518-178RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487813PMC
January 2019

Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK.

Am J Physiol Lung Cell Mol Physiol 2019 01 8;316(1):L157-L174. Epub 2018 Nov 8.

Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, The University of Sydney , Sydney, New South Wales , Australia.

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https://www.physiology.org/doi/10.1152/ajplung.00306.2018
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http://dx.doi.org/10.1152/ajplung.00306.2018DOI Listing
January 2019

Novel drug delivery approaches in treating pulmonary fibrosis.

Panminerva Med 2018 Dec 26;60(4):238-240. Epub 2018 Feb 26.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, Australia.

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http://dx.doi.org/10.23736/S0031-0808.18.03428-6DOI Listing
December 2018

The role of environmental exposure to non-cigarette smoke in lung disease.

Clin Transl Med 2018 Dec 5;7(1):39. Epub 2018 Dec 5.

School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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http://dx.doi.org/10.1186/s40169-018-0217-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279673PMC
December 2018

Targeting microRNAs using nanotechnology in pulmonary diseases.

Panminerva Med 2018 Dec;60(4):230-231

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, Australia.

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http://dx.doi.org/10.23736/S0031-0808.18.03459-6DOI Listing
December 2018

Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches.

Biomed Pharmacother 2018 Nov 29;107:1218-1229. Epub 2018 Aug 29.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI) & School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S07533322183380
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http://dx.doi.org/10.1016/j.biopha.2018.08.101DOI Listing
November 2018

Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD.

Respir Res 2018 Nov 3;19(1):211. Epub 2018 Nov 3.

Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, The University of Sydney, Sydney, Australia.

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https://respiratory-research.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12931-018-0919-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215599PMC
November 2018

Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.

Drugs 2018 Nov;78(16):1717-1740

Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Locked Bag-1322, Newnham Drive, Launceston, TAS, 7248, Australia.

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http://link.springer.com/10.1007/s40265-018-1001-8
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http://dx.doi.org/10.1007/s40265-018-1001-8DOI Listing
November 2018

Role of Oxidative Stress in the Pathology and Management of Human Tuberculosis.

Oxid Med Cell Longev 2018 11;2018:7695364. Epub 2018 Oct 11.

School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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https://www.hindawi.com/journals/omcl/2018/7695364/
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http://dx.doi.org/10.1155/2018/7695364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201333PMC
November 2018

Functional relevance of SATB1 in immune regulation and tumorigenesis.

Biomed Pharmacother 2018 Aug 14;104:87-93. Epub 2018 May 14.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.05.045DOI Listing
August 2018

Microbiome as therapeutics in vesicular delivery.

Biomed Pharmacother 2018 Aug 29;104:738-741. Epub 2018 May 29.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, Australia; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW 2305, Australia.

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http://dx.doi.org/10.1016/j.biopha.2018.05.099DOI Listing
August 2018

Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics.

Respir Res 2018 08 2;19(1):145. Epub 2018 Aug 2.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, HMRI building, Callaghan, NSW, 2308, Australia.

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http://dx.doi.org/10.1186/s12931-018-0851-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090696PMC
August 2018

IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis.

Am J Pathol 2018 07 22;188(7):1625-1639. Epub 2018 Apr 22.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales; Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia; Priority Research Centre for Digestive Health and Neurogastroenterology, University of Newcastle, Callaghan, New South Wales. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.03.016DOI Listing
July 2018

Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells.

Am J Physiol Lung Cell Mol Physiol 2018 06 25;314(6):L922-L935. Epub 2018 Jan 25.

Respiratory Cellular and Molecular Biology, Woolcock Institute of Medical Research, University of Sydney , Sydney , Australia.

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https://www.physiology.org/doi/10.1152/ajplung.00438.2017
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http://dx.doi.org/10.1152/ajplung.00438.2017DOI Listing
June 2018

Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches.

Pharmacol Ther 2018 05 27;185:155-169. Epub 2017 Dec 27.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, New South Wales, Australia; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1016/j.pharmthera.2017.12.009DOI Listing
May 2018

Immunological axis of curcumin-loaded vesicular drug delivery systems.

Future Med Chem 2018 04 5;10(8):839-844. Epub 2018 Apr 5.

School of Biomedical Sciences & Pharmacy, University of Newcastle, Newcastle, NSW 2308, Australia.

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http://dx.doi.org/10.4155/fmc-2017-0245DOI Listing
April 2018

Tumor suppressor role of miR-503.

Panminerva Med 2018 Mar 22;60(1):17-24. Epub 2017 Nov 22.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, Australia -

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http://dx.doi.org/10.23736/S0031-0808.17.03386-9DOI Listing
March 2018

Advancements in nano drug delivery systems: a challenge for biofilms in respiratory diseases.

Panminerva Med 2018 03 25;60(1):35-36. Epub 2018 Jan 25.

Department of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.

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http://dx.doi.org/10.23736/S0031-0808.18.03402-XDOI Listing
March 2018

Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease.

Am J Physiol Lung Cell Mol Physiol 2018 02 12;314(2):L298-L317. Epub 2017 Oct 12.

Priority Research Centre for Healthy Lungs, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute and University of Newcastle, Callaghan, New South Wales , Australia.

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http://dx.doi.org/10.1152/ajplung.00154.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866502PMC
February 2018

Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?

Eur Respir Rev 2017 Dec 25;26(146). Epub 2017 Oct 25.

Experimental Studies, National Heart and Lung Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.1183/16000617.0040-2017DOI Listing
December 2017

Upregulated pneumococcal adhesion molecule (platelet-activating factor receptor) may predispose COPD patients to community-acquired pneumonia.

Int J Chron Obstruct Pulmon Dis 2017 24;12:3111-3113. Epub 2017 Oct 24.

School of Medicine, University of Tasmania, Hobart, TAS, Australia.

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http://dx.doi.org/10.2147/COPD.S151142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661495PMC
November 2017

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.

PLoS One 2017 1;12(9):e0184260. Epub 2017 Sep 1.

Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184260PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580912PMC
October 2017

Potential Mechanisms of Microbial Pathogens in Idiopathic Interstitial Lung Disease.

Chest 2017 10;152(4):899-900

Breathe Well Centre of Research Excellence for Chronic Respiratory Disease and Lung Ageing, University of Tasmania, Launceston, Australia.

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http://dx.doi.org/10.1016/j.chest.2017.05.024DOI Listing
October 2017

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD).

Sci Rep 2017 10 17;7(1):13392. Epub 2017 Oct 17.

NHMRC Centre for Research Excellence for Chronic Respiratory Disease, School of Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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http://dx.doi.org/10.1038/s41598-017-13888-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645352PMC
October 2017

Steroid resistance and concomitant respiratory infections: A challenging battle in pulmonary clinic.

EXCLI J 2017 29;16:981-985. Epub 2017 Jun 29.

School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW2308, Australia.

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http://dx.doi.org/10.17179/excli2017-425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579404PMC
June 2017