Publications by authors named "Philip Lazarovici"

100Publications

FoxO3a suppresses neuropeptide W expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis.

Int J Biol Sci 2020 25;16(15):2775-2787. Epub 2020 Aug 25.

Center of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Macau, China.

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http://dx.doi.org/10.7150/ijbs.45619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545709PMC
August 2020

Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults.

Peptides 2020 Sep 1;134:170399. Epub 2020 Sep 1.

School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2020.170399DOI Listing
September 2020

Neurotropic activity and safety of methylene-cycloalkylacetate (MCA) derivative 3-(3-allyl-2-methylenecyclohexyl) propanoic acid.

ACS Chem Neurosci 2020 09 3;11(17):2577-2589. Epub 2020 Aug 3.

The Institute for Drug Research, Division of Pharmacology, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.

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http://dx.doi.org/10.1021/acschemneuro.0c00255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497641PMC
September 2020

Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway.

J Cell Mol Med 2020 Jun 29;24(11):6208-6219. Epub 2020 Apr 29.

Faculty of Health Sciences, University of Macau, Macau, China.

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http://dx.doi.org/10.1111/jcmm.15249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294164PMC
June 2020

Signaling Network of Forkhead Family of Transcription Factors (FOXO) in Dietary Restriction.

Cells 2019 Dec 31;9(1). Epub 2019 Dec 31.

Centre of Reproduction, Development & Aging and Institute of Translation Medicine, Faculty of Health Sciences, University of Macau, Macau 999078, China.

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http://dx.doi.org/10.3390/cells9010100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016766PMC
December 2019

Artemether Activation of AMPK/GSK3(ser9)/Nrf2 Signaling Confers Neuroprotection towards Amyloid-Induced Neurotoxicity in 3xTg Alzheimer's Mouse Model.

Oxid Med Cell Longev 2019 21;2019:1862437. Epub 2019 Nov 21.

Centre for Reproduction, Development & Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.

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http://dx.doi.org/10.1155/2019/1862437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907052PMC
May 2020

Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90-CREB pathway.

Stem Cell Res Ther 2019 10 26;10(1):312. Epub 2019 Oct 26.

Centre of Reproduction, Development and Aging, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau SAR, China.

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http://dx.doi.org/10.1186/s13287-019-1419-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815409PMC
October 2019

Measurements of Cell Death Induced by Snake and Spider's Venoms and Derived Toxins.

Methods Mol Biol 2020 ;2068:239-268

Faculty of Medicine, School of Pharmacy, Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1007/978-1-4939-9845-6_13DOI Listing
January 2020

Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists.

Methods Mol Biol 2020 ;2068:205-223

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9845-6_11DOI Listing
January 2020

Snake- and Spider-Venom-Derived Toxins as Lead Compounds for Drug Development.

Methods Mol Biol 2020 ;2068:3-26

Faculty of Medicine, School of Pharmacy, Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1007/978-1-4939-9845-6_1DOI Listing
January 2020

From Snake Venom's Disintegrins and C-Type Lectins to Anti-Platelet Drugs.

Toxins (Basel) 2019 05 27;11(5). Epub 2019 May 27.

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.3390/toxins11050303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563238PMC
May 2019

Tuftelin Is Required for NGF-Induced Differentiation of PC12 Cells.

J Mol Neurosci 2019 May 21;68(1):135-143. Epub 2019 Mar 21.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1007/s12031-019-01292-1DOI Listing
May 2019

Neuroprotective Effects of Bioactive Compounds and MAPK Pathway Modulation in "Ischemia"-Stressed PC12 Pheochromocytoma Cells.

Brain Sci 2018 Feb 8;8(2). Epub 2018 Feb 8.

School of Pharmacy, the Institute for Drug Research, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 9112102, Israel.

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http://www.mdpi.com/2076-3425/8/2/32
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http://dx.doi.org/10.3390/brainsci8020032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836051PMC
February 2018

Nerve growth factor plays a role in the neurotherapeutic effect of a CD45 pan-hematopoietic subpopulation derived from human umbilical cord blood in a traumatic brain injury model.

Cytotherapy 2018 02 20;20(2):245-261. Epub 2017 Dec 20.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.jcyt.2017.11.008DOI Listing
February 2018

Methylene-Cycloalkylacetate (MCA) Scaffold-Based Compounds as Novel Neurotropic Agents.

ACS Chem Neurosci 2018 04 29;9(4):691-698. Epub 2017 Dec 29.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine , The Hebrew University of Jerusalem , Jerusalem 91120 , Israel.

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http://dx.doi.org/10.1021/acschemneuro.7b00473DOI Listing
April 2018

Human Umbilical Cord Blood CD45 Pan-Hematopoietic Cells Induced a Neurotherapeutic Effect in Mice with Traumatic Brain Injury: Immunophenotyping, Comparison of Maternal and Neonatal Parameters, and Immunomodulation.

J Mol Neurosci 2018 Feb 16;64(2):185-199. Epub 2017 Dec 16.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1007/s12031-017-1008-8DOI Listing
February 2018

Nerve Growth Factor-Induced Angiogenesis: 2. The Quail Chorioallantoic Membrane Assay.

Methods Mol Biol 2018 ;1727:251-259

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7571-6_19DOI Listing
July 2018

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Methods Mol Biol 2018 ;1727:239-250

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7571-6_18DOI Listing
July 2018

Dysbindin-1 Involvement in the Etiology of Schizophrenia.

Int J Mol Sci 2017 Sep 22;18(10). Epub 2017 Sep 22.

Faculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.

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http://dx.doi.org/10.3390/ijms18102044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666726PMC
September 2017

The involvement of DARPP-32 in the pathophysiology of schizophrenia.

Oncotarget 2017 Aug 21;8(32):53791-53803. Epub 2017 Apr 21.

Faculty of Health Sciences, University of Macau, Taipa, Macau, China.

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http://dx.doi.org/10.18632/oncotarget.17339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581150PMC
August 2017

The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.

Toxins (Basel) 2017 03 16;9(3). Epub 2017 Mar 16.

School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, P.O.Box 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.3390/toxins9030107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371862PMC
March 2017

Protein toxins of the Echis coloratus viper venom directly activate TRPV1.

Biochim Biophys Acta Gen Subj 2017 Mar 4;1861(3):615-623. Epub 2017 Jan 4.

Institute for Drug Research (IDR), School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2017.01.004DOI Listing
March 2017

Novel Synthetic PEGylated Conjugate of α-Lipoic Acid and Tempol Reduces Cell Death in a Neuronal PC12 Clonal Line Subjected to Ischemia.

ACS Chem Neurosci 2016 10 22;7(10):1452-1462. Epub 2016 Aug 22.

School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem , P.O. Box 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1021/acschemneuro.6b00211DOI Listing
October 2016

Solid nano-in-nanoparticles for potential delivery of siRNA.

J Control Release 2017 07 20;257:144-155. Epub 2016 May 20.

The Institute for Drug Research of the School of Pharmacy, Faculty of Medicine, The Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.jconrel.2016.05.043DOI Listing
July 2017

Enhanced Re-Endothelialization of Decellularized Rat Lungs.

Tissue Eng Part C Methods 2016 05 1;22(5):439-50. Epub 2016 Apr 1.

1 Department of Bioengineering, College of Engineering, Temple University , Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1089/ten.TEC.2016.0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870653PMC
May 2016

Revascularization of decellularized lung scaffolds: principles and progress.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 25;309(11):L1273-85. Epub 2015 Sep 25.

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, Pennsylvania;

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http://dx.doi.org/10.1152/ajplung.00237.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669341PMC
December 2015

Mesenchymal stem cells for therapeutic applications in pulmonary medicine.

Br Med Bull 2015 Sep 10;115(1):45-56. Epub 2015 Jun 10.

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA 19122, USA Temple Institute for Regenerative Medicine and Engineering (TIME), Temple University, Philadelphia, PA 19122, USA

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http://dx.doi.org/10.1093/bmb/ldv026DOI Listing
September 2015

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki.

Biochim Biophys Acta 2015 Jun 7;1850(6):1169-79. Epub 2015 Feb 7.

Temple University, College of Engineering, Department of Bioengineering, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2015.02.002DOI Listing
June 2015

Human placental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF.

Biochim Biophys Acta 2015 Feb 15;1853(2):422-30. Epub 2014 Nov 15.

Pharmacology, School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem, P.O. Box 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1016/j.bbamcr.2014.11.009DOI Listing
February 2015

IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult.

J Mol Neurosci 2015 Apr 23;55(4):931-40. Epub 2014 Oct 23.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.

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http://dx.doi.org/10.1007/s12031-014-0448-7DOI Listing
April 2015

Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells.

J Mol Neurosci 2014 Nov 31;54(3):574-85. Epub 2014 Jul 31.

Faculty of Medicine, School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1007/s12031-014-0388-2DOI Listing
November 2014

Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.

J Pharmacol Exp Ther 2014 Sep 17;350(3):506-19. Epub 2014 Jun 17.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel (T.M., J.K., O.B., A.L., G.C., P.L.); Department of Bioengineering, College of Engineering, Temple University, Philadelphia, Pennsylvania (C.M.); Department of Chemistry, Bar Ilan University, Ramat-Gan, Israel (E.N., H.S.); Center for Molecular Medicine, Department of Vascular Matrix Biology, Frankfurt University Hospital, Excellence Cluster Cardio-Pulmonary System, Frankfurt, Germany (J.A.E.); and Institute for Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany (J.A.E.)

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http://dx.doi.org/10.1124/jpet.114.214643DOI Listing
September 2014

Cytocompatibility of novel extracellular matrix protein analogs of biodegradable polyester polymers derived from α-hydroxy amino acids.

J Biomater Sci Polym Ed 2014 25;25(6):608-24. Epub 2014 Feb 25.

a Department of Bioengineering and Temple Institute for Regenerative Medicine and Engineering , Temple University , Philadelphia , PA 19122 , USA.

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http://dx.doi.org/10.1080/09205063.2014.888303DOI Listing
November 2014

The effects of a chactoid scorpion venom and its purified toxins on rat blood pressure and mast cells histamine release.

Toxins (Basel) 2013 Jul 29;5(8):1332-42. Epub 2013 Jul 29.

Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, POB 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.3390/toxins5081332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760037PMC
July 2013

Near infrared optical visualization of epidermal growth factor receptors levels in COLO205 colorectal cell line, orthotopic tumor in mice and human biopsies.

Int J Mol Sci 2013 Jul 12;14(7):14669-88. Epub 2013 Jul 12.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://dx.doi.org/10.3390/ijms140714669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742266PMC
July 2013

P-glycoprotein-dependent resistance of cancer cells toward the extrinsic TRAIL apoptosis signaling pathway.

Biochem Pharmacol 2013 Sep 14;86(5):584-96. Epub 2013 Jun 14.

Laboratory of Molecular Immunology, Division of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1016/j.bcp.2013.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000015PMC
September 2013

Tissue factor activity and ECM-related gene expression in human aortic endothelial cells grown on electrospun biohybrid scaffolds.

Biomacromolecules 2013 May 18;14(5):1338-48. Epub 2013 Apr 18.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, United States.

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http://pubs.acs.org/doi/10.1021/bm400450m
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http://dx.doi.org/10.1021/bm400450mDOI Listing
May 2013

Identification of inhibitors of α2β1 integrin, members of C-lectin type proteins, in Echis sochureki venom.

Toxicol Appl Pharmacol 2013 May 13;269(1):34-42. Epub 2013 Mar 13.

Department of Biology, Temple University, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.1016/j.taap.2013.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627822PMC
May 2013

Identification of α2β1 integrin inhibitor VP-i with anti-platelet properties in the venom of Vipera palaestinae.

Toxicon 2013 Mar 11;64:96-105. Epub 2013 Jan 11.

Center for Molecular Medicine, Department of Vascular Matrix Biology, Frankfurt University Hospital, Excellence Cluster Cardio-Pulmonary System, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.toxicon.2013.01.001DOI Listing
March 2013

Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.

J Basic Clin Physiol Pharmacol 2013 ;24(1):81-4

Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1515/jbcpp-2012-0045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938895PMC
June 2013

Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

J Mol Neurosci 2013 Oct 12;51(2):249-61. Epub 2012 Dec 12.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1007/s12031-012-9933-zDOI Listing
October 2013

Vixapatin (VP12), a c-type lectin-protein from Vipera xantina palestinae venom: characterization as a novel anti-angiogenic compound.

Toxins (Basel) 2012 10 18;4(10):862-77. Epub 2012 Oct 18.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://dx.doi.org/10.3390/toxins4100862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496993PMC
October 2012

Neural stem cells: therapeutic potential for neurodegenerative diseases.

Br Med Bull 2012 17;104:7-19. Epub 2012 Sep 17.

The School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1093/bmb/lds024DOI Listing
November 2013

Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair.

J Mol Neurosci 2013 Feb 10;49(2):334-46. Epub 2012 Aug 10.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s12031-012-9863-9DOI Listing
February 2013

Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models.

J Mol Neurosci 2012 Nov 8;48(3):526-40. Epub 2012 Jun 8.

School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem, POB 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1007/s12031-012-9818-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955207PMC
November 2012

Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.

Int J Dev Neurosci 2012 Oct 5;30(6):465-9. Epub 2012 Jun 5.

Integrated Cellular Tissue Engineering & Regenerative Medicine Laboratory, School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19102, USA.

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http://dx.doi.org/10.1016/j.ijdevneu.2012.05.007DOI Listing
October 2012

Importance of interaction between nerve growth factor and α9β1 integrin in glial tumor angiogenesis.

Neuro Oncol 2012 Jul 17;14(7):890-901. Epub 2012 May 17.

Department of Biology Temple University Hospital, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.1093/neuonc/nos119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379805PMC
July 2012

Alimentary 'green' proteins as electrospun scaffolds for skin regenerative engineering.

J Tissue Eng Regen Med 2013 Dec 12;7(12):994-1008. Epub 2012 Apr 12.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/term.1493DOI Listing
December 2013

Biphasic influence of hypoxia on tuftelin expression in mouse mesenchymal C3H10T1/2 stem cells.

Eur J Oral Sci 2011 Dec;119 Suppl 1:55-61

Dental Research Laboratory, Institute of Dental Sciences, Faculty of Dental Medicine, The Hebrew University of Jerusalem - Hadassah, Jerusalem, Israel.

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http://dx.doi.org/10.1111/j.1600-0722.2011.00861.xDOI Listing
December 2011

Pharmacological aspects of Vipera xantina palestinae venom.

Toxins (Basel) 2011 11 14;3(11):1420-32. Epub 2011 Nov 14.

School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://dx.doi.org/10.3390/toxins3111420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237004PMC
November 2011

Proline-rich Akt substrate of 40kDa (PRAS40): a novel downstream target of PI3k/Akt signaling pathway.

Cell Signal 2012 Jan 31;24(1):17-24. Epub 2011 Aug 31.

Neuropharmacology, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.

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http://dx.doi.org/10.1016/j.cellsig.2011.08.010DOI Listing
January 2012

Neuroprotection by human umbilical cord blood-derived progenitors in ischemic brain injuries.

Arch Ital Biol 2011 Jun;149(2):233-45

The School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.4449/aib.v149i2.1370DOI Listing
June 2011

High plasma levels and effective lymphatic uptake of docetaxel in an orally available nanotransporter formulation.

Cancer Res 2011 Apr 1;71(8):3018-28. Epub 2011 Mar 1.

Faculty of Medicine, The Institute for Drug Research, The School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3118DOI Listing
April 2011

Cetuximab-labeled liposomes containing near-infrared probe for in vivo imaging.

Nanomedicine 2011 Aug 25;7(4):480-8. Epub 2011 Jan 25.

Casali Institute of Applied Chemistry, Institute of Chemistry and Center for Nanoscience and Nanotechnology, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.nano.2011.01.001DOI Listing
August 2011

Co-electrospun blends of PLGA, gelatin, and elastin as potential nonthrombogenic scaffolds for vascular tissue engineering.

Biomacromolecules 2011 Feb 23;12(2):399-408. Epub 2010 Dec 23.

School of Biomedical Engineering, Science and Health Systems, Department of Chemistry, Drexel University, Philadelphia, Pennsylvania, 19104, USA.

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http://dx.doi.org/10.1021/bm101149rDOI Listing
February 2011

Fibronectin-mediated upregulation of α5β1 integrin and cell adhesion during differentiation of mouse embryonic stem cells.

Cell Adh Migr 2011 Jan-Feb;5(1):73-82. Epub 2011 Jan 1.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038102PMC
http://dx.doi.org/10.4161/cam.5.1.13704DOI Listing
April 2011

Human umbilical cord blood stem cells: rational for use as a neuroprotectant in ischemic brain disease.

Int J Mol Sci 2010 Sep 21;11(9):3513-28. Epub 2010 Sep 21.

The School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel; E-Mails: (H.A.-Z.); (S.L.).

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http://dx.doi.org/10.3390/ijms11093513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956109PMC
September 2010

Tissue regeneration potential in human umbilical cord blood.

Best Pract Res Clin Haematol 2010 Jun;23(2):291-303

Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S15216926100001
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http://dx.doi.org/10.1016/j.beha.2010.04.001DOI Listing
June 2010

The induction of tuftelin expression in PC12 cell line during hypoxia and NGF-induced differentiation.

J Cell Physiol 2011 Jan;226(1):165-72

Dental Research Laboratory, Faculty of Dental Medicine, Institute of Dental Sciences, The Hebrew University of Jerusalem-Hadassah, Jerusalem, Israel.

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http://dx.doi.org/10.1002/jcp.22318DOI Listing
January 2011

Peaceful use of disastrous neurotoxicants.

Neurotoxicology 2010 Sep 8;31(5):608-20. Epub 2010 Jul 8.

Service and Unit of Neurology and Toxicology, Shaare Zedek Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.neuro.2010.06.009DOI Listing
September 2010

Transient signaling of Erk1/2, Akt and PLCgamma induced by nerve growth factor in brain capillary endothelial cells.

Vascul Pharmacol 2010 Sep-Oct;53(3-4):107-14. Epub 2010 Apr 29.

Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.vph.2010.04.005DOI Listing
December 2010

Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells.

Mol Cell Biochem 2010 Jun 11;339(1-2):201-13. Epub 2010 Feb 11.

School of Pharmacy-Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, POB 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1007/s11010-010-0386-9DOI Listing
June 2010

Cardiac microvascular endothelial cells express and release nerve growth factor but not fibroblast growth factor-2.

In Vitro Cell Dev Biol Anim 2010 May 29;46(5):469-76. Epub 2010 Jan 29.

The School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1007/s11626-009-9267-5DOI Listing
May 2010

Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of Erk phosphorylation.

J Mol Neurosci 2010 May 10;41(1):183-92. Epub 2009 Dec 10.

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, POB 12065, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1007/s12031-009-9318-0DOI Listing
May 2010

Effect of VP12 and viperistatin on inhibition of collagen-receptor-dependent melanoma metastasis.

Cancer Biol Ther 2009 Aug 13;8(15):1507-16. Epub 2009 Aug 13.

Department of Biology, Temple University, College of Science and Technology, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.4161/cbt.8.15.8999DOI Listing
August 2009

Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma.

Neuro Oncol 2008 Dec;10(6):968-80

Department of Neuroscience, Center for Neurovirology and Cancer Biology, School of Medicine, Temple University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1215/15228517-2008-047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719011PMC
December 2008

Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors.

Exp Neurol 2009 Mar 25;216(1):83-94. Epub 2008 Nov 25.

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S001448860800439
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http://dx.doi.org/10.1016/j.expneurol.2008.11.006DOI Listing
March 2009

Quantitative assessment of neuronal differentiation in three-dimensional collagen gels using enhanced green fluorescence protein expressing PC12 pheochromocytoma cells.

J Mol Neurosci 2009 Mar 16;37(3):225-37. Epub 2008 Jul 16.

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

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http://dx.doi.org/10.1007/s12031-008-9123-1DOI Listing
March 2009

Pardaxin, a fish toxin peptide interaction with a biomimetic phospholipid/polydiacetylene membrane assay.

Peptides 2008 Sep 23;29(9):1620-5. Epub 2008 May 23.

Ilse Katz Center for Meso- and Nano-Scale Science and Technology, Ben Gurion University, Beer-Sheva, 84105, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S019697810800224
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http://dx.doi.org/10.1016/j.peptides.2008.05.012DOI Listing
September 2008

Integrin alpha9 beta1 is a receptor for nerve growth factor and other neurotrophins.

J Cell Sci 2008 Feb 29;121(Pt 4):504-13. Epub 2008 Jan 29.

Department of Neuroscience, Center for Neurovirology and Cancer Biology, Temple University, School of Medicine, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.1242/jcs.000232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744358PMC
February 2008

Neuronal conditioning medium and nerve growth factor induce neuronal differentiation of collagen-adherent progenitors derived from human umbilical cord blood.

J Mol Neurosci 2007 ;32(3):179-91

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1007/s12031-007-0027-2DOI Listing
November 2007

VEGF-related protein isolated from Vipera palestinae venom, promotes angiogenesis.

Growth Factors 2007 Apr;25(2):108-17

Department of Neuroscience, Center for Neurovirology, School of Medicine, Temple University, 1900 N. 12th Street, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.1080/08977190701532385DOI Listing
April 2007

The activated nerve growth factor receptor p-TrkA is selectively expressed in advanced-stage ovarian carcinoma.

Hum Pathol 2007 Jan 25;38(1):140-6. Epub 2006 Sep 25.

Department of Gynecology, Ulleval University Hospital, University of Oslo, N-0407 Oslo, Norway.

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http://dx.doi.org/10.1016/j.humpath.2006.06.027DOI Listing
January 2007

Neuroprotective effects of the stable nitroxide compound Tempol on 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in the Nerve Growth Factor-differentiated model of pheochromocytoma PC12 cells.

Eur J Pharmacol 2006 Nov 26;549(1-3):50-7. Epub 2006 Aug 26.

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, P.O.Box 12065, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1016/j.ejphar.2006.08.022DOI Listing
November 2006

Nerve growth factor (NGF) promotes angiogenesis in the quail chorioallantoic membrane.

Endothelium 2006 Jan-Feb;13(1):51-9

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1080/10623320600669053DOI Listing
September 2006

Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development.

Curr Pharm Des 2006 ;12(21):2609-22

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://dx.doi.org/10.2174/138161206777698738DOI Listing
August 2006

In vitro and in vivo reversal of MDR1-mediated multidrug resistance by KT-5720: implications on hematological malignancies.

Leuk Res 2006 Sep 20;30(9):1151-8. Epub 2006 Mar 20.

Laboratory of Molecular Immunobiology, Department of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1016/j.leukres.2006.02.016DOI Listing
September 2006

Neuroprotection by NGF in the PC12 in vitro OGD model: involvement of mitogen-activated protein kinases and gene expression.

Ann N Y Acad Sci 2005 Aug;1053:84-96

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://doi.wiley.com/10.1196/annals.1344.008
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August 2005

Nerve growth factor-induced migration of endothelial cells.

J Pharmacol Exp Ther 2005 Dec 25;315(3):1220-7. Epub 2005 Aug 25.

Calhoun Chair Professor of Cellular Tissue Engineering, School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut St., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1124/jpet.105.093252DOI Listing
December 2005

Structural determinants of the selectivity of KTS-disintegrins for the alpha1beta1 integrin.

FEBS Lett 2004 Nov;577(3):478-82

Center for Neurovirology and Cancer Biology, Temple University, College of Science and Technology, 1900 N., 12th Street, Philadelphia, PA 19122, USA.

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http://dx.doi.org/10.1016/j.febslet.2004.10.050DOI Listing
November 2004

Expression of activated TrkA protein in melanocytic tumors: relationship to cell proliferation and clinical outcome.

Am J Clin Pathol 2004 Sep;122(3):412-20

Department of Pathology, Norwegian Radium Hospital, HF, Montebello, Oslo.

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http://dx.doi.org/10.1309/CHFH-EYAT-44WW-P7J3DOI Listing
September 2004

Expression of the nerve growth factor receptors TrkA and p75 in malignant mesothelioma.

Lung Cancer 2004 May;44(2):159-65

Department of Pathology, The Norwegian Radium Hospital, Montebello N-0310 Oslo, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1016/j.lungcan.2003.11.014DOI Listing
May 2004

Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma.

Breast Cancer Res Treat 2004 Jan;83(2):119-28

Department of Pathology, The Norwegian Radium Hospital, University of Oslo, Montebello, Oslo, Norway.

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http://dx.doi.org/10.1023/B:BREA.0000010704.17479.8aDOI Listing
January 2004

Nerve growth factor pretreatment attenuates oxygen and glucose deprivation-induced c-Jun amino-terminal kinase 1 and stress-activated kinases p38alpha and p38beta activation and confers neuroprotection in the pheochromocytoma PC12 Model.

J Mol Neurosci 2004 ;22(3):237-50

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1385/jmn:22:3:237DOI Listing
June 2004

Apoptotic characteristics of cell death and the neuroprotective effect of homocarnosine on pheochromocytoma PC12 cells exposed to ischemia.

J Neurosci Res 2004 Feb;75(4):499-507

Department of Pharmacology and Experimental Therapeutics, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://doi.wiley.com/10.1002/jnr.20008
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http://dx.doi.org/10.1002/jnr.20008DOI Listing
February 2004