Philip L McCarthy

Philip L McCarthy

UNVERIFIED PROFILE

Are you Philip L McCarthy?   Register this Author

Register author
Philip L McCarthy

Philip L McCarthy

Publications by authors named "Philip L McCarthy"

Are you Philip L McCarthy?   Register this Author

100Publications

2945Reads

49Profile Views

Methods to prevent and treat relapse after hematopoietic stem cell transplantation with tyrosine kinase inhibitors, immunomodulating drugs, deacetylase inhibitors, and hypomethylating agents.

Bone Marrow Transplant 2019 04 23;54(4):497-507. Epub 2018 Jul 23.

Stem Cell Transplant Program, University Hospital Cleveland Medical Center, Case Western Reserve University, Cleveland, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41409-018-0269-3
Publisher Site
http://dx.doi.org/10.1038/s41409-018-0269-3DOI Listing
April 2019

Commentary on "Is posttransplant lenalidomide the standard-of-care after an autotransplant for plasma cell myeloma" by Giovanni Barosi and Robert Peter Gale.

Leukemia 2019 02 11;33(2):565-566. Epub 2019 Jan 11.

Department of Medicine, Transplant and Cellular Therapy Program, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41375-018-0359-7
Publisher Site
http://dx.doi.org/10.1038/s41375-018-0359-7DOI Listing
February 2019

Should Overall Survival Remain an Endpoint for Multiple Myeloma Trials?

Curr Hematol Malig Rep 2019 02;14(1):31-38

Department of Medicine, Blood and Marrow Transplant Center, Transplant and Cellular Therapy Program, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11899-019-0495-9DOI Listing
February 2019

Determination of Minimal Residual Disease in Multiple Myeloma: Does It Matter?

Curr Hematol Malig Rep 2019 02;14(1):39-46

Department of Internal Medicine, University of Nebraska Medical Center, 986840 Nebraska Medical Center, Omaha, NE, 68198, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11899-019-0497-7DOI Listing
February 2019

Host-Derived Serine Protease Inhibitor 6 Provides Granzyme B-Independent Protection of Intestinal Epithelial Cells in Murine Graft-versus-Host Disease.

Biol Blood Marrow Transplant 2018 12 10;24(12):2397-2408. Epub 2018 Jul 10.

Department of Immunology; Roswell Park Comprehensive Cancer Center, Buffalo, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286216PMC
December 2018

Next-Generation Drugs Targeting the Cereblon Ubiquitin Ligase.

J Clin Oncol 2018 07 1;36(20):2101-2104. Epub 2018 May 1.

Sarah A. Holstein, University of Nebraska Medical Center, Omaha, NE; and Jens Hillengass and Philip L. McCarthy, Roswell Park Comprehensive Cancer Center, Buffalo, NY.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2018.77.9637DOI Listing
July 2018

Update on the role of lenalidomide in patients with multiple myeloma.

Ther Adv Hematol 2018 Jul 26;9(7):175-190. Epub 2018 May 26.

Department of Medicine, Blood and Marrow Transplant Center, Roswell Park Comprehensive Cancer Center, Buffalo, Elm and Carlton Streets, CSC 815, NY 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2040620718775629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041862PMC
July 2018

BPX-501 T cells interfere with minimal residual disease evaluation of B-cell acute lymphoblastic leukemia.

Bone Marrow Transplant 2018 05 17;53(5):651-653. Epub 2018 Jan 17.

Department of Medicine, Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41409-017-0036-xDOI Listing
May 2018

Blockade of Host β2-Adrenergic Receptor Enhances Graft-versus-Tumor Effect through Modulating APCs.

J Immunol 2018 04 14;200(7):2479-2488. Epub 2018 Feb 14.

Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1701752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860988PMC
April 2018

Lenalidomide in combination or alone as maintenance therapy following autologous stem cell transplant in patients with multiple myeloma: a review of options for and against.

Expert Opin Pharmacother 2017 Dec 1;18(18):1975-1985. Epub 2017 Dec 1.

d Blood and Marrow Transplant Program , Roswell Park Cancer Institute , Buffalo , NY , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14656566.2017.1409207DOI Listing
December 2017

T Cell-Derived CD70 Delivers an Immune Checkpoint Function in Inflammatory T Cell Responses.

J Immunol 2017 11 18;199(10):3700-3710. Epub 2017 Oct 18.

Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1700380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687300PMC
November 2017

Lenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis.

J Clin Oncol 2017 Oct 25;35(29):3279-3289. Epub 2017 Jul 25.

Philip L. McCarthy, Roswell Park Cancer Institute, Buffalo, NY; Sarah A. Holstein, University of Nebraska Medical Center, Omaha, NE; Maria Teresa Petrucci, University La Sapienza; Antonio Palumbo, Takeda Italia, Rome; Patrizia Tosi, Rimini Hospital, Rimini; Sara Bringhen and Francesca Gay, University of Torino, Torino; Pellegrino Musto, Cancer Institute for Research and Care and The Referral Cancer Center of Basilicata, Rionero in Vulture, Italy; Paul G. Richardson and Kenneth C. Anderson, Dana-Farber Cancer Institute, Boston, MA; Cyrille Hulin and Gerald Marit, Bordeaux Centre Hospitalier Universitaire, Bordeaux; Denis Caillot, Dijon University Hospital Center, Dijon; Philippe Moreau, University Hospital Hôtel-Dieu, Nantes; Michel Attal, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France; Sin-Ho Jung, Duke University, Durham, NC; and Zhinuan Yu, Benjamin Winograd, and Robert D. Knight, Celgene Corporation, Summit, NJ.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.72.6679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652871PMC
October 2017

Immunomodulatory Drugs in Multiple Myeloma: Mechanisms of Action and Clinical Experience.

Drugs 2017 Apr;77(5):505-520

Department of Medicine, Blood and Marrow Transplant Center, Roswell Park Cancer Institute, Buffalo, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40265-017-0689-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705939PMC
April 2017

Quantifying MHC dextramer-induced NFAT activation in antigen-specific T cells as a functional response parameter.

Methods 2017 01 17;112:75-83. Epub 2016 Jun 17.

Department of Flow and Image Cytometry, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymeth.2016.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821144PMC
January 2017

Role of stem cell transplant and maintenance therapy in plasma cell disorders.

Hematology Am Soc Hematol Educ Program 2016 Dec;2016(1):504-511

Department of Internal Medicine, Division of Oncology and Hematology, University of Nebraska Medical Center, Omaha, NE.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/asheducation-2016.1.504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142442PMC
December 2016

Improved survival with salvage autologous stem-cell transplantation in myeloma.

Lancet Haematol 2016 Jul;3(7):e306-7

Roswell Park Cancer Institute, Buffalo, NY 14263, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2352-3026(16)30058-8DOI Listing
July 2016

Granzyme B Contributes to the Optimal Graft-Versus-Tumor Effect Mediated by Conventional CD4 T Cells.

J Immunol Res Ther 2016 30;1(1):22-28. Epub 2016 Apr 30.

Department of Immunology, Roswell Park Cancer Institute, Buffalo, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070611PMC
April 2016

Continued role for ASCT in multiple myeloma.

Lancet Oncol 2015 Dec 17;16(16):1571-3. Epub 2015 Nov 17.

Roswell Park Cancer Institute, BMT Program, Department of Medicine, Buffalo, NY 14263, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S14702045150045
Publisher Site
http://dx.doi.org/10.1016/S1470-2045(15)00457-XDOI Listing
December 2015

Prospective Validation of the Predictive Power of the Hematopoietic Cell Transplantation Comorbidity Index: A Center for International Blood and Marrow Transplant Research Study.

Biol Blood Marrow Transplant 2015 Aug 7;21(8):1479-87. Epub 2015 Apr 7.

Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2015.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512746PMC
August 2015

Synchronous presentation of monoclonal gammopathy and Fabry nephropathy; diagnostic renal biopsy obviates initiation of myeloma therapy.

Ann Hematol 2015 Jun 10;94(6):1067-8. Epub 2015 Feb 10.

Department of Clinical Hematology-Oncology, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY, 14263, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-015-2307-1DOI Listing
June 2015

Management of relapsed multiple myeloma after autologous stem cell transplant.

Biol Blood Marrow Transplant 2015 May 31;21(5):793-8. Epub 2015 Jan 31.

Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2014.12.026DOI Listing
May 2015

Long-term survival after transplantation of unrelated donor peripheral blood or bone marrow hematopoietic cells for hematologic malignancy.

Biol Blood Marrow Transplant 2015 Jan 22;21(1):55-9. Epub 2014 Sep 22.

Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2014.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272909PMC
January 2015

Multiple myeloma.

Hematol Oncol Clin North Am 2014 Dec 30;28(6):1113-29. Epub 2014 Sep 30.

Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08898588140011
Publisher Site
http://dx.doi.org/10.1016/j.hoc.2014.08.010DOI Listing
December 2014

Maintenance therapy for multiple myeloma.

Hematol Oncol Clin North Am 2014 Oct 22;28(5):839-59. Epub 2014 Jul 22.

Myeloma Unit, Division of Hematology, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, University of Torino, Via Genova 3, Torino 10126, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hoc.2014.06.006DOI Listing
October 2014

Early versus late preemptive allogeneic hematopoietic cell transplantation for relapsed or refractory acute myeloid leukemia.

Biol Blood Marrow Transplant 2014 Sep 24;20(9):1369-74. Epub 2014 May 24.

Department of Medicine, BMT Program, Roswell Park Cancer Institute, Buffalo, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2014.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292802PMC
September 2014

Strategies for induction, autologous hematopoietic stem cell transplantation, consolidation, and maintenance for transplantation-eligible multiple myeloma patients.

Hematology Am Soc Hematol Educ Program 2013 ;2013:496-503

1Roswell Park Cancer Institute, BMT Program, Department of Medicine, Buffalo, NY.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/asheducation-2013.1.496DOI Listing
July 2014

Second transplant as a standard for multiple myeloma.

Lancet Oncol 2014 Jul 16;15(8):786-8. Epub 2014 Jun 16.

Adult Blood and Marrow Transplant (BMT) Program, Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(14)70279-7DOI Listing
July 2014

Toxic tacrolimus levels after application of topical tacrolimus and use of occlusive dressings in two bone marrow transplant recipients with cutaneous graft-versus-host disease.

Pharmacotherapy 2014 Jun 3;34(6):e60-4. Epub 2014 Apr 3.

Department of Pharmacy Services, State University of New York at Buffalo, Buffalo, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/phar.1418DOI Listing
June 2014

Remestemcel-L for acute graft-versus-host disease therapy.

Expert Opin Biol Ther 2014 Feb 19;14(2):261-9. Epub 2013 Dec 19.

Roswell Park Cancer Institute, Department of Medicine, BMT Program , Elm and Carlton Streets, Buffalo, NY 14263 , USA +1 716 845 8412 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14712598.2014.873027DOI Listing
February 2014

The emerging role of consolidation and maintenance therapy for transplant-eligible multiple myeloma patients.

Expert Rev Hematol 2014 Feb 29;7(1):55-66. Epub 2014 Jan 29.

Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/17474086.2014.878645DOI Listing
February 2014

Simplified validated prognostic model for progression-free survival after autologous transplantation for hodgkin lymphoma.

Biol Blood Marrow Transplant 2013 Dec 3;19(12):1740-4. Epub 2013 Oct 3.

Division of Blood and Marrow Transplant, Roswell Park Cancer Institute, Buffalo, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2013.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906436PMC
December 2013

Where are we going with autologous transplantation for multiple myeloma?

Biol Blood Marrow Transplant 2013 Nov 18;19(11):1532-3. Epub 2013 Sep 18.

BMT Program, Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2013.09.006DOI Listing
November 2013

Unrelated donor allogeneic hematopoietic cell transplantation is underused as a curative therapy in eligible patients from the United States.

Biol Blood Marrow Transplant 2013 Oct 25;19(10):1459-64. Epub 2013 Jun 25.

Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2013.06.014DOI Listing
October 2013

Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect.

J Immunol 2013 Feb 21;190(3):1341-50. Epub 2012 Dec 21.

Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1201554DOI Listing
February 2013

Multiple myeloma: future directions in autologous transplantation and novel agents.

Biol Blood Marrow Transplant 2013 Jan;19(1 Suppl):S20-5

Division of Hematology Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53206, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2012.11.002DOI Listing
January 2013

Part I: the role of maintenance therapy in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation.

J Natl Compr Canc Netw 2013 Jan;11(1):35-42

Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.6004/jnccn.2013.0006DOI Listing
January 2013

A TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease.

J Immunol 2012 Nov 8;189(10):4719-27. Epub 2012 Oct 8.

Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1201206DOI Listing
November 2012

Progressive chronic lymphocytic leukemia after allogeneic hematopoietic cell transplantation.

J Natl Compr Canc Netw 2012 Oct;10(10):1203-6

Department of Medicine, BMT Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.6004/jnccn.2012.0127DOI Listing
October 2012

"Sowing dragon's teeth?" Myeloma and AML.

Blood 2011 Oct;118(15):4008-9

Roswell Park Cancer Institute, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2011-08-372243DOI Listing
October 2011

Self-determinism: alloBMT for AML.

Blood 2011 Feb;117(7):2080-1

Roswell Park Cancer Institute, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2010-12-325340DOI Listing
February 2011

Multiparameter flow cytometry for the diagnosis and monitoring of small GPI-deficient cellular populations.

Cytometry B Clin Cytom 2010 Sep 7;78(5):348-56. Epub 2010 Jun 7.

Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cyto.b.20519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937167PMC
September 2010

Accelerated bone mineral density loss occurs with similar incidence and severity, but with different risk factors, after autologous versus allogeneic hematopoietic cell transplantation.

Biol Blood Marrow Transplant 2010 Aug 24;16(8):1130-7. Epub 2010 Feb 24.

Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2010.02.017DOI Listing
August 2010

Reversible cardiotoxicity with tyrosine kinase inhibitors.

Clin Adv Hematol Oncol 2010 Feb;8(2):128-32

Department of Medicine, State University of New York at Buffalo, Buffalo, NY 14214, USA.

View Article

Download full-text PDF

Source
February 2010