Philip J Thompson

Philip J Thompson

UNVERIFIED PROFILE

Are you Philip J Thompson?   Register this Author

Register author
Philip J Thompson

Philip J Thompson

Publications by authors named "Philip J Thompson"

Are you Philip J Thompson?   Register this Author

92Publications

2270Reads

50Profile Views

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0197-6DOI Listing
September 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0157-1DOI Listing
August 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-017-0014-7
Publisher Site
http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma.

Oncotarget 2017 Sep 24;8(44):78193-78207. Epub 2017 Aug 24.

Institute for Respiratory Health, Centre for Respiratory Health, Harry Perkins Institute of Medical Research, QEII Medical Centre, School of Biomedical Sciences, University of Western Australia, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.20409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652849PMC
September 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

Field Walking Tests Are Reliable and Responsive to Exercise Training in People With Non-Cystic Fibrosis Bronchiectasis.

J Cardiopulm Rehabil Prev 2015 Nov-Dec;35(6):439-45

Physiotherapy, Alfred Health (Drs Lee and Holland and Ms Burge), Physiotherapy, La Trobe University (Dr Holland), and Allergy, Immunology and Respiratory Medicine, Alfred Health (Dr Stirling), Melbourne, Victoria, Australia; Institute for Breathing and Sleep (Drs Lee, Holland, Hill, and McDonald and Ms Rautela), Physiotherapy (Dr Hill and Ms Rautela), and Respiratory and Sleep Medicine (Dr McDonald), Austin Health, Heidelberg, Victoria, Australia; Physiotherapy, Sir Charles Gairdner Hospital (Ms Cecins and Dr Jenkins), Lung Institute of Western Australia (Ms Cecins and Drs Thompson and Jenkins), and Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital (Dr Thompson), Nedlands, Western Australia, Australia; and Community Physiotherapy Services (Ms Cecins) and Physiotherapy and Exercise Science, Curtin University (Drs Thompson and Jenkins), Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HCR.0000000000000130DOI Listing
August 2016

Histone Modifications and Asthma. The Interface of the Epigenetic and Genetic Landscapes.

Am J Respir Cell Mol Biol 2016 Jan;54(1):3-12

1 Institute for Respiratory Health, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2015-0050TRDOI Listing
January 2016

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Meta-analysis identifies seven susceptibility loci involved in the atopic march.

Nat Commun 2015 Nov 6;6:8804. Epub 2015 Nov 6.

Max-Delbrück-Center (MDC) for Molecular Medicine, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms9804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667629PMC
November 2015

Pulmonary Sporotrichosis: An Evolving Clinical Paradigm.

Semin Respir Crit Care Med 2015 Oct 23;36(5):756-66. Epub 2015 Sep 23.

The Lung Health Clinic, Hollywood Hospital and the Sir Charles Gairdner Hospital Nedlands, and The School of Medicine and Pharmacology University of Western Australia, Perth, WA, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0035-1562901DOI Listing
October 2015

Corticosteroid therapy for pneumonia.

Lancet 2015 Sep;386(9997):953

Department of Infectious Diseases and Microbiology, The Alfred Hospital, Melbourne, Victoria, Australia; Monash University, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(15)00061-6DOI Listing
September 2015

Loss of miR-223 and JNK Signaling Contribute to Elevated Stathmin in Malignant Pleural Mesothelioma.

Mol Cancer Res 2015 Jul 30;13(7):1106-18. Epub 2015 Mar 30.

Institute for Respiratory Health and Centre for Asthma, Allergy and Respiratory Research, School of Medicine and Pharmacology, University of Western Australia, Harry Perkins Institute of Medical Research, Nedlands, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-14-0442DOI Listing
July 2015

Beta2 adrenergic receptor (ADRβ2) haplotype pair (2/4) is associated with severe asthma.

PLoS One 2014 1;9(4):e93695. Epub 2014 Apr 1.

Molecular Genetics and Inflammation Unit, Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Crawley, Nedlands, Western Australia, Australia; School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093695PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972120PMC
June 2015

The role of receptor for advanced glycation end products in airway inflammation in CF and CF related diabetes.

Sci Rep 2015 Mar 10;5:8931. Epub 2015 Mar 10.

1] Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia [2] Lung Institute of Western Australia, Nedlands, Western Australia [3] Centre for Asthma, Allergy and Respiratory Research, School of Medicine and Pharmacology, University of Western Australia, Western Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep08931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354142PMC
March 2015

Survey of asthma management in Thailand - the asthma insight and management study.

Asian Pac J Allergy Immunol 2015 Mar;33(1):14-20

Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12932/AP0473.33.1.2015DOI Listing
March 2015

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis.

Oncotarget 2015 Jan;6(3):1519-30

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, School of Medicine and Pharmacology, University of Western Australia, Harry Perkins Institute of Medical Research, Nedlands, WA, Australia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359311PMC
http://dx.doi.org/10.18632/oncotarget.2729DOI Listing
January 2015

Impaired function of regulatory T-cells in patients with chronic obstructive pulmonary disease (COPD).

Immunobiology 2014 Dec 21;219(12):975-9. Epub 2014 Jul 21.

Lung Institute of Western Australia, The University of Western Australia, Perth, Australia; Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Australia; School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia; Department of Respiratory and Sleep Medicine, Royal Perth Hospital, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imbio.2014.07.005DOI Listing
December 2014

Impaired CTLA-4 responses in COPD are associated with systemic inflammation.

Cell Mol Immunol 2014 Nov 24;11(6):606-8. Epub 2014 Mar 24.

1] Centre for Asthma, Allergy and Respiratory Research, Lung Institute of Western Australia, Nedlands, Australia [2] School of Medicine and Pharmacology, Nedlands, Australia [3] Department of Respiratory and Sleep Medicine, Royal Perth Hospital, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cmi.2014.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220831PMC
November 2014

Novel kinin B₁ receptor splice variant and 5'UTR regulatory elements are responsible for cell specific B₁ receptor expression.

PLoS One 2014 27;9(1):e87175. Epub 2014 Jan 27.

Molecular Genetics and Inflammation Unit, Lung Institute of Western Australia (LIWA), Perth, Western Australia, Australia ; Centre for Asthma, Allergy and Respiratory Research (CAARR), School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia ; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Western Australia, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087175PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903636PMC
September 2014

Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.

N Engl J Med 2014 Sep 8;371(13):1189-97. Epub 2014 Sep 8.

From the Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, Amsterdam (E.H.B.); the Department of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh Asthma Institute at the University of Pittsburgh Medical Center-University of Pittsburgh School of Medicine, Pittsburgh (S.E.W.); the Lung Institute of Western Australia, Nedlands, and the Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Crawley - both in Australia (P.J.T.); Respiratory Therapeutic Area, GlaxoSmithKline, Research Triangle Park, NC (C.M.P., S.W.Y., H.G.O.); and Clinical Statistics, GlaxoSmithKline, Stockley Park (O.N.K.), and the Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford (I.D.P.) - both in the United Kingdom.

View Article

Download full-text PDF

Source
http://www.usahealthsystem.com/workfiles/com_docs%2Facademic
Web Search
http://www.nejm.org/doi/abs/10.1056/NEJMoa1403291
Publisher Site
http://dx.doi.org/10.1056/NEJMoa1403291DOI Listing
September 2014

Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.

PLoS One 2013 24;8(6):e66685. Epub 2013 Jun 24.

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, Department of Medicine, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066685PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691204PMC
March 2014

Inhaled, dual release liposomal ciprofloxacin in non-cystic fibrosis bronchiectasis (ORBIT-2): a randomised, double-blind, placebo-controlled trial.

Thorax 2013 Sep 16;68(9):812-7. Epub 2013 May 16.

Department of Respiratory Medicine, Mater Medical Research Institute and University of Queensland, Mater Adult Hospital, South Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2013-203207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770250PMC
September 2013

Insights, attitudes and perceptions about asthma and its treatment: findings from a multinational survey of patients from 8 Asia-Pacific countries and Hong Kong.

Respirology 2013 Aug;18(6):957-67

Lung Institute of WA and Centre for Asthma, Allergy and Respiratory Research University of Western Australia, Nedlands, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.12137DOI Listing
August 2013

Pulmonary sporotrichosis: case series and systematic analysis of literature on clinico-radiological patterns and management outcomes.

Med Mycol 2013 Jul 4;51(5):534-44. Epub 2013 Jan 4.

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/13693786.2012.751643DOI Listing
July 2013

Pseudobronchiectasis after pertussis and mycoplasma infection.

Am J Respir Crit Care Med 2012 Aug;186(3):292-4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/ajrccm.186.3.292DOI Listing
August 2012

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Chih-Mei Chen Adaikalavan Ramasamy Klaus Bønnelykke Liesbeth Duijts Manuel A Ferreira Alexessander Couto Alves Jacob P Thyssen Eva Albrecht Hansjörg Baurecht Bjarke Feenstra Patrick M A Sleiman Pirro Hysi Nicole M Warrington Ivan Curjuric Ronny Myhre John A Curtin Maria M Groen-Blokhuis Marjan Kerkhof Annika Sääf Andre Franke David Ellinghaus Regina Fölster-Holst Emmanouil Dermitzakis Stephen B Montgomery Holger Prokisch Katharina Heim Anna-Liisa Hartikainen Anneli Pouta Juha Pekkanen Alexandra I F Blakemore Jessica L Buxton Marika Kaakinen David L Duffy Pamela A Madden Andrew C Heath Grant W Montgomery Philip J Thompson Melanie C Matheson Peter Le Souëf Beate St Pourcain George Davey Smith John Henderson John P Kemp Nicholas J Timpson Panos Deloukas Susan M Ring H-Erich Wichmann Martina Müller-Nurasyid Natalija Novak Norman Klopp Elke Rodríguez Wendy McArdle Allan Linneberg Torkil Menné Ellen A Nohr Albert Hofman André G Uitterlinden Cornélia M van Duijn Fernando Rivadeneira Johan C de Jongste Ralf J P van der Valk Matthias Wjst Rain Jogi Frank Geller Heather A Boyd Jeffrey C Murray Cecilia Kim Frank Mentch Michael March Massimo Mangino Tim D Spector Veronique Bataille Craig E Pennell Patrick G Holt Peter Sly Carla M T Tiesler Elisabeth Thiering Thomas Illig Medea Imboden Wenche Nystad Angela Simpson Jouke-Jan Hottenga Dirkje Postma Gerard H Koppelman Henriette A Smit Cilla Söderhäll Bo Chawes Eskil Kreiner-Møller Hans Bisgaard Erik Melén Dorret I Boomsma Adnan Custovic Bo Jacobsson Nicole M Probst-Hensch Lyle J Palmer Daniel Glass Hakon Hakonarson Mads Melbye Deborah L Jarvis Vincent W V Jaddoe Christian Gieger David P Strachan Nicholas G Martin Marjo-Riitta Jarvelin Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2011 Dec 25;44(2):187-92. Epub 2011 Dec 25.

Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK.

View Article

Download full-text PDF

Source
http://www.tweelingenregister.org/nederlands/verslaggeving/N
Web Search
http://www.nature.com/doifinder/10.1038/ng.1017
Publisher Site
http://dx.doi.org/10.1038/ng.1017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272375PMC
December 2011

Remote ischemic preconditioning stimulus decreases the expression of kinin receptors in human neutrophils.

J Surg Res 2011 Nov 29;171(1):311-6. Epub 2009 Nov 29.

School of Surgery, University of Western Australia and Cardiothoracic Surgery Unit, Sir Charles Gairdner Hospital, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jss.2009.11.011DOI Listing
November 2011

Mesothelial cell differentiation into osteoblast- and adipocyte-like cells.

J Cell Mol Med 2011 Oct;15(10):2095-105

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, WA, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1582-4934.2010.01212.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394220PMC
October 2011

Lys-des[Arg9]-bradykinin alters migration and production of interleukin-12 in monocyte-derived dendritic cells.

Am J Respir Cell Mol Biol 2011 Sep 22;45(3):542-9. Epub 2010 Dec 22.

Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, and Lung Institute of Western Australia, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2010-0238OCDOI Listing
September 2011

Increases in urinary 9alpha,11beta-prostaglandin f2 indicate mast cell activation in wine-induced asthma.

Int Arch Allergy Immunol 2009 6;149(2):127-32. Epub 2009 Jan 6.

Lung Institute of Western Australia Inc., Centre for Asthma, Allergy and Respiratory Research, Ground Floor, E Block, Sir Charles Gairdner Hospital, Verdun Street, Nedlands, W.A. 6009, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000189195DOI Listing
June 2009

Kallikreins, kininogens and kinin receptors on circulating and synovial fluid neutrophils: role in kinin generation in rheumatoid arthritis.

Rheumatology (Oxford) 2009 May 1;48(5):490-6. Epub 2009 Mar 1.

Department of Geriatrics, Nelson Mandela School of Medicine, University of Natal, Durban, South Africa.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/rheumatology/kep016DOI Listing
May 2009

Expression of kinin receptors on eosinophils: comparison of asthmatic patients and healthy subjects.

J Leukoc Biol 2009 Mar 26;85(3):544-52. Epub 2008 Nov 26.

Lung Institute of Western Australia, Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0508283DOI Listing
March 2009

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

Nat Genet 2009 Mar 8;41(3):342-7. Epub 2009 Feb 8.

deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.323DOI Listing
March 2009

Effect of protective filters on fire fighter respiratory health: field validation during prescribed burns.

Am J Ind Med 2009 Jan;52(1):76-87

School of Population Health M431, The University of Western Australia, Crawley, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajim.20651DOI Listing
January 2009

Expression of tissue and plasma kallikreins and kinin B1 and B2 receptors in lung cancer.

Biol Chem 2008 Sep;389(9):1225-33

Lung Institute of Western Australia, Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Nedlands, WA 6009, Australia.

View Article

Download full-text PDF

Source
http://www.degruyter.com/dg/viewarticle.fullcontentlink:pdfe
Web Search
http://www.degruyter.com/view/j/bchm.2008.389.issue-9/bc.200
Publisher Site
http://dx.doi.org/10.1515/BC.2008.139DOI Listing
September 2008

Observational studies on the effect of dietary antioxidants on asthma: a meta-analysis.

Respirology 2008 Jun 10;13(4):528-36. Epub 2008 Apr 10.

Department of Respiratory Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1843.2008.01286.xDOI Listing
June 2008

Tolerance and rebound with zafirlukast in patients with persistent asthma.

J Negat Results Biomed 2008 May 19;7. Epub 2008 May 19.

Respiratory Research Group, Menzies Research Institute, University of Tasmania Hobart, Tasmania, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1477-5751-7-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426667PMC
May 2008

Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma.

Int Immunopharmacol 2008 Feb 6;8(2):300-6. Epub 2007 Sep 6.

Lung Institute of Western Australia, Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2007.08.015DOI Listing
February 2008

Comparison of kinin B(1) and B(2) receptor expression in neutrophils of asthmatic and non-asthmatic subjects.

Int Immunopharmacol 2007 Dec 6;7(14):1862-8. Epub 2007 Aug 6.

Lung Institute of Western Australia and Centre for Asthma, Allergy & Respiratory Research, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2007.07.012DOI Listing
December 2007

Physiological concentrations of transforming growth factor beta1 selectively inhibit human dendritic cell function.

Int Immunopharmacol 2007 Dec 31;7(14):1924-33. Epub 2007 Jul 31.

Lung Institute of Western Australia and Centre for Asthma, Allergy & Respiratory Research, The University of Western Australia, Perth, WA, Australia.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S156757690700196
Publisher Site
http://dx.doi.org/10.1016/j.intimp.2007.07.003DOI Listing
December 2007

Novel expression of kallikreins, kallikrein-related peptidases and kinin receptors in human pleural mesothelioma.

Biol Chem 2007 Nov;388(11):1235-42

Lung Institute of Western Australia, Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Nedlands WA, Australia.

View Article

Download full-text PDF

Source
https://www.degruyter.com/view/j/bchm.2007.388.issue-11/bc.2
Publisher Site
http://dx.doi.org/10.1515/BC.2007.139DOI Listing
November 2007

Omalizumab (Xolair) in patients with steroid-resistant asthma: lessons to be learnt.

Respirology 2007 Nov;12 Suppl 3:S29-34; discussion S45-7

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1843.2007.01017.xDOI Listing
November 2007

How to choose the right journal for your manuscript.

Chest 2007 Sep;132(3):1073-6

Lung Institute of Western Australia, Ground Floor E Block, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.07-1340DOI Listing
September 2007

Expression of kinin B1 and B2 receptors in immature, monocyte-derived dendritic cells and bradykinin-mediated increase in intracellular Ca2+ and cell migration.

J Leukoc Biol 2007 Jun 27;81(6):1445-54. Epub 2007 Feb 27.

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0106055DOI Listing
June 2007

Current status of tissue kallikrein inhibitors: importance in cancer.

Curr Opin Investig Drugs 2007 Jun;8(6):462-8

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Ground Floor E Block, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands 6009, Perth, Australia.

View Article

Download full-text PDF

Source
June 2007

Respirology year-in-review 2006: Basic science.

Respirology 2007 Mar;12(2):184-90

Lung Institute of Western Australia, Centre for Asthma, Allergy & Respiratory Research, University of Western Australia, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1843.2007.01045.xDOI Listing
March 2007

Oxidative stress and lipid-derived inflammatory mediators during acute exacerbations of cystic fibrosis.

Respirology 2007 Jan;12(1):63-9

Cardio-Respiratory Research Group, University of Tasmania Medical School, Hobart, Tasmania, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1843.2006.00962.xDOI Listing
January 2007

Concomitant activation of extracellular signal-regulated kinase and induction of COX-2 stimulates maximum prostaglandin E2 synthesis in human airway epithelial cells.

Prostaglandins Other Lipid Mediat 2006 Dec 2;81(3-4):126-35. Epub 2006 Oct 2.

Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S109888230600122
Publisher Site
http://dx.doi.org/10.1016/j.prostaglandins.2006.08.006DOI Listing
December 2006

Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.

J Immunol 2006 Oct;177(8):5595-603

Division of Molecular Biosciences, The John Curtin School of Medical Research, Australian National University, Canberra, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.177.8.5595DOI Listing
October 2006

Oxidative stress and antioxidant deficiencies in asthma: potential modification by diet.

Redox Rep 2005 ;10(5):247-55

Asthma & Allergy Research Institute (Inc) and Centre for Asthma, Allergy & Respiratory Research, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1179/135100005X70233DOI Listing
September 2006

ADAM33 haplotypes are associated with asthma in a large Australian population.

Eur J Hum Genet 2006 Sep 14;14(9):1027-36. Epub 2006 Jun 14.

The Co-operative Research Centre (CRC) for Asthma, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.ejhg.5201662DOI Listing
September 2006

Effect of protective filters on fire fighter respiratory health during simulated bushfire smoke exposure.

Am J Ind Med 2006 Sep;49(9):740-50

School of Population Health, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajim.20369DOI Listing
September 2006

Six minute walk distance in healthy subjects aged 55-75 years.

Respir Med 2006 Apr 17;100(4):658-65. Epub 2005 Oct 17.

School of Physiotherapy, Curtin University of Technology, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmed.2005.08.003DOI Listing
April 2006

A confocal microscopic study of solitary pulmonary neuroendocrine cells in human airway epithelium.

Respir Res 2005 Oct 10;6:115. Epub 2005 Oct 10.

Asthma and Allergy Research Institute, Sir Charles Gairdner Hospital, Nedlands, 6009, Western Australia.

View Article

Download full-text PDF

Source
http://respiratory-research.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/1465-9921-6-115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277851PMC
October 2005

Distinguishing asthma and chronic obstructive pulmonary disease: why, why not and how?

Med J Aust 2005 Jul;183(1 Suppl):S35-7

Woolcock Institute of Medical Research, Royal Prince Alfred Hospital, PO Box M77, Missenden Road, Camperdown, NSW 2050, Australia.

View Article

Download full-text PDF

Source
July 2005

Activation of proteinase-activated receptor-2 in mesothelial cells induces pleural inflammation.

Am J Physiol Lung Cell Mol Physiol 2005 Apr 10;288(4):L734-40. Epub 2004 Dec 10.

Centre for Respiratory Research, Rayne Institute, University College London, 5 University St., London WC1E 6JJ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00173.2004DOI Listing
April 2005

Higher prostaglandin e2 production by dendritic cells from subjects with asthma compared with normal subjects.

Am J Respir Crit Care Med 2004 Sep 19;170(5):485-91. Epub 2004 May 19.

Asthma and Allergy Research Institute, University of Western Australia, West Perth, WA, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200311-1595OCDOI Listing
September 2004

alpha(v)beta(3) Integrin interacts with the transforming growth factor beta (TGFbeta) type II receptor to potentiate the proliferative effects of TGFbeta1 in living human lung fibroblasts.

J Biol Chem 2004 Sep 8;279(36):37726-33. Epub 2004 Jun 8.

Asthma and Allergy Research Institute and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M403010200DOI Listing
September 2004

Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma.

J Allergy Clin Immunol 2004 May;113(5):889-95

Co-operative Research Centre for Asthma and the Asthma and Allergy Research Institute (Inc), Sir Charles Gairdner Hospital, University of Western Australia, Perth, WA 6009, Australia.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S009167490400982
Publisher Site
http://dx.doi.org/10.1016/j.jaci.2004.02.008DOI Listing
May 2004

Activated human dendritic cells express inducible cyclo-oxygenase and synthesize prostaglandin E2 but not prostaglandin D2.

Immunol Cell Biol 2004 Feb;82(1):47-54

Asthma and Allergy Research Institute and School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1711.2004.01213.xDOI Listing
February 2004

Inverse effects of interleukin-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs.

Am J Respir Cell Mol Biol 2003 Oct 24;29(4):490-8. Epub 2003 Apr 24.

Asthma & Allergy Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia.

View Article

Download full-text PDF

Source
http://www.atsjournals.org/doi/abs/10.1165/rcmb.2002-0262OC
Publisher Site
http://dx.doi.org/10.1165/rcmb.2002-0262OCDOI Listing
October 2003

Peptidase allergen Der p 1 initiates apoptosis of epithelial cells independently of tight junction proteolysis.

Mol Membr Biol 2003 Jan-Mar;20(1):71-81

Department of Pharmacology & Clinical Pharmacology, St George's Hospital Medical School, London, UK.

View Article

Download full-text PDF

Source
October 2003

Allergic and asthmatic reactions to alcoholic drinks.

Addict Biol 2003 Mar;8(1):3-11

Department of Health, The University of Western Australia, Western Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/1355621031000069828DOI Listing
March 2003

Dendritic cell maturation and IL-12 synthesis induced by the synthetic immune-response modifier S-28463.

J Leukoc Biol 2002 Nov;72(5):932-8

Asthma & Allergy Research Institute and Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands.

View Article

Download full-text PDF

Source
November 2002

Comparing transforming growth factor-beta2, talc and bleomycin as pleurodesing agents in sheep.

Respirology 2002 Sep;7(3):209-16

Department of Pulmonary Medicine, St Thomas Hospital, Nashville, Tennessee, USA.

View Article

Download full-text PDF

Source
September 2002

Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts.

Br J Pharmacol 2002 Jul;136(5):793-801

Asthma and Allergy Research Institute, Sir Charles Gairdner Hospital and Department of Medicine, University of Western Australia, Nedlands, Western Australia 6009.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.bjp.0704769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573397PMC
July 2002

Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells.

J Immunol 2002 Apr;168(7):3577-85

Division of Inflammation and Infectious Diseases, Department of Microbiology, Asthma & Allergy Research Institute, University of Western Australia, Nedlands, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.168.7.3577DOI Listing
April 2002

Transforming growth factor beta induces vascular endothelial growth factor elaboration from pleural mesothelial cells in vivo and in vitro.

Am J Respir Crit Care Med 2002 Jan;165(1):88-94

Department of Pulmonary Medicine, St. Thomas Hospital and Vanderbilt University, Nashville, Tennessee 37202, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/ajrccm.165.1.2104006DOI Listing
January 2002