Philip Gerretsen

Philip Gerretsen

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Philip Gerretsen

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Modulation of brain activity with transcranial direct current stimulation: Targeting regions implicated in impaired illness awareness in schizophrenia.

Eur Psychiatry 2019 Sep 19;61:63-71. Epub 2019 Jul 19.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, (CAMH), University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eurpsy.2019.06.007DOI Listing
September 2019

Resting-state functional connectivity in treatment response and resistance in schizophrenia: A systematic review.

Schizophr Res 2019 Sep 19;211:10-20. Epub 2019 Jul 19.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.07.020DOI Listing
September 2019

Clozapine response trajectories and predictors of non-response in treatment-resistant schizophrenia: a chart review study.

Eur Arch Psychiatry Clin Neurosci 2019 Aug 19. Epub 2019 Aug 19.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), 250 College Street, Toronto, ON, M5T 1R8, Canada.

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http://dx.doi.org/10.1007/s00406-019-01053-6DOI Listing
August 2019

Alterations in body mass index and waist-to-hip ratio in never and minimally treated patients with psychosis: A systematic review and meta-analysis.

Schizophr Res 2019 Jun 23;208:420-429. Epub 2019 Jan 23.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.01.005DOI Listing
June 2019

Insight and medication adherence in schizophrenia: An analysis of the CATIE trial.

Neuropharmacology 2019 May 9:107634. Epub 2019 May 9.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2019.05.011DOI Listing
May 2019

Glutamatergic Neurometabolite Levels in Patients With Ultra-Treatment-Resistant Schizophrenia: A Cross-Sectional 3T Proton Magnetic Resonance Spectroscopy Study.

Biol Psychiatry 2019 04 26;85(7):596-605. Epub 2018 Sep 26.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00063223183185
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http://dx.doi.org/10.1016/j.biopsych.2018.09.009DOI Listing
April 2019

The effects of illness severity, cognition, and estimated antipsychotic dopamine receptor occupancy on insight into the illness in schizophrenia: An analysis of clinical antipsychotic trials of intervention effectiveness (CATIE) data.

Prog Neuropsychopharmacol Biol Psychiatry 2019 03 30;89:207-213. Epub 2018 Aug 30.

Multimodal Imaging Group, Research Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Ontario, Canada; Geriatric Mental Health Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2018.08.033DOI Listing
March 2019

A meta-analysis of transcranial direct current stimulation for schizophrenia: "Is more better?"

J Psychiatr Res 2019 Mar 10;110:117-126. Epub 2018 Dec 10.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2018.12.009DOI Listing
March 2019

What proportion of striatal D2 receptors are occupied by endogenous dopamine at baseline? A meta-analysis with implications for understanding antipsychotic occupancy.

Neuropharmacology 2019 Mar 30. Epub 2019 Mar 30.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 1 Kings College Circle, Toronto, Ontario, M5S 1A8, Canada.

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http://dx.doi.org/10.1016/j.neuropharm.2019.03.034DOI Listing
March 2019

The effect of ethnicity and immigration on treatment resistance in schizophrenia.

Compr Psychiatry 2019 Feb 7;89:28-32. Epub 2018 Dec 7.

Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; University of Naples "Federico II", Naples, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0010440X183020
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http://dx.doi.org/10.1016/j.comppsych.2018.12.003DOI Listing
February 2019

Alterations in body mass index and waist-to-hip ratio in never and minimally treated patients with psychosis: A systematic review and meta-analysis.

Schizophr Res 2019 Jun 23;208:420-429. Epub 2019 Jan 23.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.01.005DOI Listing
June 2019

Lead (Pb) in Alzheimer's Dementia: A Systematic Review of Human Case- Control Studies.

Curr Alzheimer Res 2019 ;16(4):353-361

Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.2174/1567205016666190311101445DOI Listing
January 2019

Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry.

Exp Eye Res 2018 10 5;175:32-41. Epub 2018 Jun 5.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.exer.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167174PMC
October 2018

The impact of delay in clozapine initiation on treatment outcomes in patients with treatment-resistant schizophrenia: A systematic review.

Psychiatry Res 2018 10 9;268:114-122. Epub 2018 Jul 9.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183056
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http://dx.doi.org/10.1016/j.psychres.2018.06.070DOI Listing
October 2018

Association Between Catastrophizing and Dizziness-Related Disability Assessed With the Dizziness Catastrophizing Scale.

JAMA Otolaryngol Head Neck Surg 2018 Oct;144(10):906-912

Multimodal Imaging Group, Research Imaging Centre, The Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoto.2018.1863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233828PMC
October 2018

The neural correlates of apathy in schizophrenia: An exploratory investigation.

Neuropsychologia 2018 09 25;118(Pt B):34-39. Epub 2017 Oct 25.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada M5T 1R8.

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https://linkinghub.elsevier.com/retrieve/pii/S00283932173040
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http://dx.doi.org/10.1016/j.neuropsychologia.2017.10.027DOI Listing
September 2018

Association Between Catastrophizing and Dizziness-Related Disability Assessed With the Dizziness Catastrophizing Scale.

JAMA Otolaryngol Head Neck Surg 2018 Oct;144(10):906-912

Multimodal Imaging Group, Research Imaging Centre, The Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoto.2018.1863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233828PMC
October 2018

Neurometabolite levels in antipsychotic-naïve/free patients with schizophrenia: A systematic review and meta-analysis of H-MRS studies.

Prog Neuropsychopharmacol Biol Psychiatry 2018 08 23;86:340-352. Epub 2018 Mar 23.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, M5T 1R8 Toronto, Ontario, Canada.; Department of Psychiatry, University of Toronto, 250 College Street, M5T 1R8 Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, 80 Workman Way, M6J 1H4 Toronto, Canada; Campbell Research Institute, Centre for Addiction and Mental Health, 1001 Queen St. W, M6J 1H4 Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2018.03.016DOI Listing
August 2018

Reprint of OASIS - Obesity Awareness and Insight Scale.

Prim Care Diabetes 2018 08 8;12(4):371-378. Epub 2018 May 8.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.pcd.2018.04.001DOI Listing
August 2018

The impact of delay in clozapine initiation on treatment outcomes in patients with treatment-resistant schizophrenia: A systematic review.

Psychiatry Res 2018 10 9;268:114-122. Epub 2018 Jul 9.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, CAMH, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183056
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http://dx.doi.org/10.1016/j.psychres.2018.06.070DOI Listing
October 2018

Reprint of OASIS - Obesity Awareness and Insight Scale.

Prim Care Diabetes 2018 08 8;12(4):371-378. Epub 2018 May 8.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.pcd.2018.04.001DOI Listing
August 2018

BASIS: The blood pressure awareness and insight scale.

J Clin Hypertens (Greenwich) 2018 Apr 10;20(4):748-756. Epub 2018 Mar 10.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/jch.13248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906154PMC
April 2018

Striatal neurometabolite levels in patients with schizophrenia undergoing long-term antipsychotic treatment: A proton magnetic resonance spectroscopy and reliability study.

Psychiatry Res Neuroimaging 2018 03 31;273:16-24. Epub 2018 Jan 31.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Campbell Institute Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.pscychresns.2018.01.004DOI Listing
March 2018

Reward motivation in humans and its relationship to dopamine D receptor availability: A pilot study with dual [C]-raclopride and [C]-(+)-PHNO imaging.

J Psychopharmacol 2018 03 14;32(3):357-366. Epub 2018 Feb 14.

1 Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1177/0269881118756059DOI Listing
March 2018

OASIS: The Obesity Awareness and Insight Scale.

Obes Med 2018 Mar 12;9:38-44. Epub 2018 Feb 12.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S24518476183000
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http://dx.doi.org/10.1016/j.obmed.2018.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260590PMC
March 2018

Reduced insulin sensitivity may be related to less striatal glutamate: An H-MRS study in healthy non-obese humans.

Eur Neuropsychopharmacol 2018 02;28(2):285-296

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada M5T 1R8; Institute of Medical Science, University of Toronto, 2374 Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2017.12.002DOI Listing
February 2018

Cross-cultural psychometric assessment of the VAGUS insight into psychosis scale - Spanish version.

Psychiatry Res 2018 01 2;259:450-454. Epub 2017 Nov 2.

Clinical Research Division, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñíz, Mexico City, Mexico.

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http://dx.doi.org/10.1016/j.psychres.2017.10.046DOI Listing
January 2018

Patients' Knowledge about Prescribed Antipsychotics and Medication Adherence in Schizophrenia: A Cross-Sectional Survey.

Pharmacopsychiatry 2017 Nov 4;50(6):264-269. Epub 2017 Jul 4.

Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1055/s-0043-113828DOI Listing
November 2017

The relationship between subcortical brain volume and striatal dopamine D receptor availability in healthy humans assessed with [ C]-raclopride and [ C]-(+)-PHNO PET.

Hum Brain Mapp 2017 11 28;38(11):5519-5534. Epub 2017 Jul 28.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.

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http://dx.doi.org/10.1002/hbm.23744DOI Listing
November 2017

Trait impulsiveness is related to smaller post-commissural putamen volumes in males but not females.

Eur J Neurosci 2017 Oct 4;46(7):2253-2264. Epub 2017 Sep 4.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON, M5T 1R8, Canada.

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http://dx.doi.org/10.1111/ejn.13661DOI Listing
October 2017

Intranasal oxytocin does not modulate jumping to conclusions in schizophrenia: Potential interactions with caudate volume and baseline social functioning.

Psychoneuroendocrinology 2017 Jul 31;81:80-87. Epub 2017 Mar 31.

Department of Psychiatry, University of British Columbia, Detwiller Pavilion, 2255 Wesbrook Mall, Vancouver, British Columbia, V6T 2A1, Canada.

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http://dx.doi.org/10.1016/j.psyneuen.2017.03.020DOI Listing
July 2017

Insight into illness and its relationship to illness severity, cognition and estimated antipsychotic dopamine receptor occupancy in schizophrenia: An antipsychotic dose reduction study.

Psychiatry Res 2017 May 1;251:20-25. Epub 2017 Feb 1.

Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan; Geriatric Mental Health Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01651781163128
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http://dx.doi.org/10.1016/j.psychres.2017.01.090DOI Listing
May 2017

Vestibular stimulation improves insight into illness in schizophrenia spectrum disorders.

Psychiatry Res 2017 May 13;251:333-341. Epub 2017 Feb 13.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; Geriatric Mental Health Program, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Campbell Mental Health Research Institute, Research Program, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.psychres.2017.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720160PMC
May 2017

Altered functional connectivity in brain networks underlying self-referential processing in delusions of reference in schizophrenia.

Psychiatry Res Neuroimaging 2017 May 9;263:32-43. Epub 2017 Mar 9.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; BC Mental Health and Addictions Research Institute, Provincial Health Services Authority, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2017.03.005DOI Listing
May 2017

GWAS analysis of treatment resistant schizophrenia: interaction effect of childhood trauma.

Pharmacogenomics 2017 May 28;18(7):663-671. Epub 2017 Apr 28.

EEG & Genetics Group, Centre for Addiction & Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.

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http://dx.doi.org/10.2217/pgs-2016-0137DOI Listing
May 2017

Insight Into Illness and Cognition in Schizophrenia in Earlier and Later Life.

J Clin Psychiatry 2017 04;78(4):e390-e397

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.4088/JCP.16m10741DOI Listing
April 2017

Impaired illness awareness and leftward visuospatial inattention in schizophrenia are attributable to a common neural deficit - Posterior parietal hemispheric imbalance.

Med Hypotheses 2017 03 16;100:19-22. Epub 2017 Jan 16.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Geriatric Psychiatry Division, Centre for Addiction and Mental Health, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.mehy.2017.01.007DOI Listing
March 2017

Cognition and Dopamine D Receptor Availability in the Striatum in Older Patients with Schizophrenia.

Am J Geriatr Psychiatry 2017 01 2;25(1):1-10. Epub 2016 Aug 2.

Geriatric Psychiatry Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Multimodal Imaging Group-Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jagp.2016.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164861PMC
January 2017

Threshold of Dopamine D2/3 Receptor Occupancy for Hyperprolactinemia in Older Patients With Schizophrenia.

J Clin Psychiatry 2016 Dec;77(12):e1557-e1563

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, 250 College St, Toronto, Ontario, M5T 1R, Canada.

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http://dx.doi.org/10.4088/JCP.15m10538DOI Listing
December 2016

Benzodiazepine Use Attenuates Cortical β-Amyloid and is Not Associated with Progressive Cognitive Decline in Nondemented Elderly Adults: A Pilot Study Using F-Florbetapir Positron Emission Tomography.

Am J Geriatr Psychiatry 2016 11 4;24(11):1028-1039. Epub 2016 May 4.

Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Multimodal Imaging Group-Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2016.04.013DOI Listing
November 2016

Β-Amyloid Burden is Not Associated with Cognitive Impairment in Schizophrenia: A Systematic Review.

Am J Geriatr Psychiatry 2016 10 29;24(10):923-39. Epub 2016 Apr 29.

Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Multimodal Imaging Group-Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2016.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026886PMC
October 2016

Tau in Late-Life Depression: A Systematic Review and Meta-Analysis.

J Alzheimers Dis 2016 09;54(2):615-33

Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.3233/JAD-160401DOI Listing
September 2016

Cortical Amyloid β Deposition and Current Depressive Symptoms in Alzheimer Disease and Mild Cognitive Impairment.

J Geriatr Psychiatry Neurol 2016 May 23;29(3):149-59. Epub 2015 Sep 23.

Faculty of Medicine, Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada Multimodal Imaging Group-Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

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http://dx.doi.org/10.1177/0891988715606230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870393PMC
May 2016

Exploring personality traits related to dopamine D2/3 receptor availability in striatal subregions of humans.

Eur Neuropsychopharmacol 2016 Apr 27;26(4):644-52. Epub 2016 Feb 27.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8; Institute of Medical Science, University of Toronto, 2374 Medical Sciences Building, 1 King׳s College Circle, Toronto, Ontario, Canada M5S 1A8; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada M5T 1R8. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2016.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805526PMC
April 2016

The effect of striatal dopamine depletion on striatal and cortical glutamate: A mini-review.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Feb 1;65:49-53. Epub 2015 Sep 1.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 2374 Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario M5T 1R8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2015.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323253PMC
February 2016

Lifetime History of Depression Predicts Increased Amyloid-β Accumulation in Patients with Mild Cognitive Impairment.

J Alzheimers Dis 2015 ;45(3):907-19

Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada Multimodal Imaging Group - Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada Department of Psychiatry, University of Toronto, Toronto, Canada Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.3233/JAD-142931DOI Listing
January 2016

Reduced insulin-receptor mediated modulation of striatal dopamine release by basal insulin as a possible contributing factor to hyperdopaminergia in schizophrenia.

Med Hypotheses 2015 Oct 24;85(4):391-6. Epub 2015 Jun 24.

Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 2374 Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario M5T 1R8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.mehy.2015.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323257PMC
October 2015

Neuroimaging findings in treatment-resistant schizophrenia: A systematic review: Lack of neuroimaging correlates of treatment-resistant schizophrenia.

Schizophr Res 2015 May 13;164(1-3):164-75. Epub 2015 Feb 13.

Multimodal Imaging Group - Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Campbell Research Institute, Centre for Addiction and Mental Health, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409508PMC
May 2015

Dopamine D₂/₃ receptor availability in the striatum of antipsychotic-free older patients with schizophrenia-A [¹¹C]-raclopride PET study.

Schizophr Res 2015 May 8;164(1-3):263-7. Epub 2015 Mar 8.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Campbell Research Institute, Centre for Addiction and Mental Health, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409531PMC
May 2015

Comparative efficacy between clozapine and other atypical antipsychotics on depressive symptoms in patients with schizophrenia: analysis of the CATIE phase 2E data.

Schizophr Res 2015 Feb 30;161(2-3):429-33. Epub 2014 Dec 30.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Campbell Research Institute, Centre for Addiction and Mental Health, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.12.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308551PMC
February 2015

Reduced insulin sensitivity is related to less endogenous dopamine at D2/3 receptors in the ventral striatum of healthy nonobese humans.

Int J Neuropsychopharmacol 2015 Feb 25;18(7):pyv014. Epub 2015 Feb 25.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada (Mr Caravaggio, Ms Borlido, Ms Feng, Dr Gerretsen, Dr Nakajima, Mr Plitman, Mr Chung, Dr Iwata, Dr Wilson, Dr Remington, and Dr Graff-Guerrero); Institute of Medical Science (Mr Caravaggio, Dr Hahn, Mr Fervaha, Dr Gerretsen, Mr Plitman, Mr Chung, Dr Wilson, Dr Remington, and Dr Graff-Guerrero), and Department of Psychiatry (Drs Hahn, Gerretsen, Nakajima, Iwata, Wilson, Remington, and Graff-Guerrero), University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/ijnp/pyv014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540108PMC
February 2015

Ventral striatum binding of a dopamine D2/3 receptor agonist but not antagonist predicts normal body mass index.

Biol Psychiatry 2015 Jan 27;77(2):196-202. Epub 2013 Mar 27.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2013.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783412PMC
January 2015

Illness denial in schizophrenia spectrum disorders: a function of left hemisphere dominance.

Hum Brain Mapp 2015 Jan 11;36(1):213-25. Epub 2014 Sep 11.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/hbm.22624
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http://dx.doi.org/10.1002/hbm.22624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268179PMC
January 2015

The VAGUS insight into psychosis scale--self-report and clinician-rated versions.

Psychiatry Res 2014 Dec 19;220(3):1084-9. Epub 2014 Aug 19.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; Division of Geriatric Psychiatry, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.psychres.2014.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470623PMC
December 2014

Impaired insight into illness and cognitive insight in schizophrenia spectrum disorders: resting state functional connectivity.

Schizophr Res 2014 Dec 8;160(1-3):43-50. Epub 2014 Nov 8.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction & Mental Health, Canada; Geriatric Mental Health Program, Centre for Addiction & Mental Health, Canada; Department of Psychiatry, University of Toronto, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction & Mental Health, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429527PMC
December 2014

Estimating endogenous dopamine levels at D2 and D3 receptors in humans using the agonist radiotracer [(11)C]-(+)-PHNO.

Neuropsychopharmacology 2014 Nov 30;39(12):2769-76. Epub 2014 May 30.

1] Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada [2] Institute of Medical Science, University of Toronto, Toronto, ON, Canada [3] Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/npp.2014.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200487PMC
November 2014

The effects of aging on insight into illness in schizophrenia: a review.

Int J Geriatr Psychiatry 2014 Nov 23;29(11):1145-61. Epub 2014 Jul 23.

University of Toronto and the Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/gps.4154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472640PMC
November 2014

Glutamate-mediated excitotoxicity in schizophrenia: a review.

Eur Neuropsychopharmacol 2014 Oct 1;24(10):1591-605. Epub 2014 Aug 1.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Campbell Institute Research Program, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2014.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470624PMC
October 2014

Insight into illness in late-life schizophrenia: a function of illness severity and premorbid intellectual function.

Schizophr Res 2013 Oct 21;150(1):217-22. Epub 2013 Aug 21.

University of Toronto and Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.schres.2013.07.025DOI Listing
October 2013

The potential role of dopamine D₃ receptor neurotransmission in cognition.

Eur Neuropsychopharmacol 2013 Aug 20;23(8):799-813. Epub 2013 Jun 20.

Multimodal Imaging Group-Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Canada M5T 1R8.

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http://dx.doi.org/10.1016/j.euroneuro.2013.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748034PMC
August 2013

Frontotemporoparietal asymmetry and lack of illness awareness in schizophrenia.

Hum Brain Mapp 2013 May 3;34(5):1035-43. Epub 2012 Jan 3.

Multimodal Imaging Group, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/hbm.21490DOI Listing
May 2013

Exploring the neural correlates of delusions of reference.

Biol Psychiatry 2011 Dec 10;70(12):1127-33. Epub 2011 Aug 10.

Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.biopsych.2011.05.037DOI Listing
December 2011

Drugs with anticholinergic properties: a current perspective on use and safety.

Expert Opin Drug Saf 2011 Sep 2;10(5):751-65. Epub 2011 Jun 2.

Geriatric Mental Health Program, Centre for Addiction & Mental Health, Canada.

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http://www.tandfonline.com/doi/full/10.1517/14740338.2011.57
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http://dx.doi.org/10.1517/14740338.2011.579899DOI Listing
September 2011

Rediscovering adverse anticholinergic effects.

J Clin Psychiatry 2011 Jun;72(6):869-70

Geriatric Mental Health Program and Multimodal Imaging Group, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.4088/JCP.11ac07093DOI Listing
June 2011

The intersection of pharmacology, imaging, and genetics in the development of personalized medicine.

Dialogues Clin Neurosci 2009 ;11(4):363-76

Centre for Addiction and Mental Health, University of Toronto, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181934PMC
March 2010

Sensitivity to antipsychotic drugs in older adults.

Curr Psychiatry Rep 2010 Feb;12(1):28-33

Centre for Addiction and Mental Health, Multimodal Imaging Group, PET Centre, 250 College Street, Toronto, ON M5T1R8, Canada.

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http://link.springer.com/10.1007/s11920-009-0080-3
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http://dx.doi.org/10.1007/s11920-009-0080-3DOI Listing
February 2010

Reversible cerebral vasoconstriction syndrome: a thunderclap headache-associated condition.

Curr Neurol Neurosci Rep 2009 Mar;9(2):108-14

Mount Sinai Hospital, 431-600 University Avenue, Toronto, Ontario, Canada.

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March 2009

Pharmacogenetics and the serotonin transporter in late-life depression.

Expert Opin Drug Metab Toxicol 2008 Dec;4(12):1465-78

Faculty of Medicine University of Toronto, Centre for Addiction and Mental Health, Division of Psychiatry, Toronto, Ontario, M5S 2S1, Canada.

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http://www.tandfonline.com/doi/full/10.1517/1742525080256027
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http://dx.doi.org/10.1517/17425250802560279 DOI Listing
December 2008

The physician: a secure base.

J Clin Oncol 2008 Nov 14;26(32):5294-6. Epub 2008 Oct 14.

Division of Psychiatry and the Palliative Care Consult Team, Sunnybrook Health Sciences Centre, and the University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2008.17.5588DOI Listing
November 2008

Acute treatment of paediatric migraine: a meta-analysis of efficacy.

J Paediatr Child Health 2008 Jan 14;44(1-2):3-9. Epub 2007 Sep 14.

Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1440-1754.2007.01206.xDOI Listing
January 2008

Reversible cerebral vasoconstriction syndrome or primary angiitis of the central nervous system?

Can J Neurol Sci 2007 Nov;34(4):467-77

Division of Neurology, Mount Sinai Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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November 2007