Philip F Binkley

Philip F Binkley

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Philip F Binkley

Publications by authors named "Philip F Binkley"

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Organizational Strategies to Create a Burnout-resistant Environment.

Clin Obstet Gynecol 2019 Sep;62(3):491-504

The Ohio State University Wexner Medical Center, Columbus, Ohio.

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http://dx.doi.org/10.1097/GRF.0000000000000459DOI Listing
September 2019

Association of Genetic Polymorphisms in the Beta-1 Adrenergic Receptor with Recovery of Left Ventricular Ejection Fraction in Patients with Heart Failure.

J Cardiovasc Transl Res 2019 Aug 12;12(4):280-289. Epub 2019 Feb 12.

Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s12265-019-09866-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690812PMC
August 2019

Burnout and Career Satisfaction Among U.S. Cardiologists.

J Am Coll Cardiol 2019 Jul;73(25):3345-3348

Department of Medicine, Division of Cardiology, Duke University School of Medicine, Duke Clinical Research Institute, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.jacc.2019.04.031DOI Listing
July 2019

Response by El Refaey et al to Letter Regarding Article, "Protein Phosphatase 2A Regulates Cardiac Na Channels".

Circ Res 2019 Apr;124(8):e60-e61

The Dorothy M. Davis Heart & Lung Research Institute, The Frick Center for Heart Failure and Arrhythmia, Department of Internal Medicine, Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, OH.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.314938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601626PMC
April 2019

The CARE Inventory: A Self-Reflective, Behavior-Based Instrument to Guide Professional Development and Mentorship of Academic Faculty.

MedEdPORTAL 2018 10 15;14:10763. Epub 2018 Oct 15.

Professor, Department of Internal Medicine, The Ohio State University College of Medicine.

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http://dx.doi.org/10.15766/mep_2374-8265.10763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342399PMC
October 2018

Etiology-dependent impairment of relaxation kinetics in right ventricular end-stage failing human myocardium.

J Mol Cell Cardiol 2018 08 5;121:81-93. Epub 2018 Jul 5.

Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States; Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, United States; Department of Internal Medicine, The Ohio State University, Columbus, OH, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103886PMC
August 2018

Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart.

Pharm Res 2017 Aug 24;34(8):1648-1657. Epub 2017 Jan 24.

Center for Pharmacogenomics and Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, 1005 BRT, 460 West 12th Ave, Columbus, Ohio, 43210, USA.

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http://dx.doi.org/10.1007/s11095-017-2102-xDOI Listing
August 2017

CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure.

Pharm Res 2017 Aug 8;34(8):1615-1625. Epub 2017 Feb 8.

Center for Pharmacogenomics, Ohio State University College of Medicine, Columbus, Ohio, USA.

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http://dx.doi.org/10.1007/s11095-017-2104-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500390PMC
August 2017

Promise of a New Role for Heart Rate Variability in the Clinical Management of Patients With Heart Failure.

Authors:
Philip F Binkley

JACC Heart Fail 2017 06 5;5(6):432-434. Epub 2017 Apr 5.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jchf.2017.02.008DOI Listing
June 2017

Determinants of Faculty Departure in an Academic Medical Center: A Time to Event Analysis.

Am J Med 2017 04 7;130(4):488-493. Epub 2017 Jan 7.

The Ohio State University College of Medicine and the Center for Faculty Advancement Mentoring and Engagement (FAME), Columbus; The Ohio State University College of Public Health, Columbus. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2016.12.011DOI Listing
April 2017

Dysfunction of the β2-spectrin-based pathway in human heart failure.

Am J Physiol Heart Circ Physiol 2016 06 22;310(11):H1583-91. Epub 2016 Apr 22.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio; Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, Columbus, Ohio; Department of Physiology and Cell Biology, Columbus, Ohio;

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http://dx.doi.org/10.1152/ajpheart.00875.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935521PMC
June 2016

What Factors Contribute to Headache-Related Disability in Teens?

Pediatr Neurol 2016 Mar 24;56:48-54. Epub 2015 Dec 24.

Center for Integrative Health and Wellness, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio; Department of Medicine, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio.

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http://dx.doi.org/10.1016/j.pediatrneurol.2015.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248515PMC
March 2016

Calcium-activated potassium current modulates ventricular repolarization in chronic heart failure.

PLoS One 2014 1;9(10):e108824. Epub 2014 Oct 1.

College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America; College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108824PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182742PMC
January 2016

The Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium.

Am J Physiol Heart Circ Physiol 2015 Dec 9;309(12):H2077-86. Epub 2015 Oct 9.

Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio; Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio; and

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http://ajpheart.physiology.org/content/ajpheart/309/12/H2077
Web Search
http://ajpheart.physiology.org/lookup/doi/10.1152/ajpheart.0
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http://dx.doi.org/10.1152/ajpheart.00685.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698421PMC
December 2015

Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations.

J Cardiovasc Pharmacol 2015 Jul;66(1):80-5

*Department of Pharmacology, Center for Pharmacogenomics, The Ohio State University Wexner Medical Center, Columbus, OH; †Children's Hospital Oakland Research Institute, Oakland, CA; ‡Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, and §Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA; and ‖Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

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http://dx.doi.org/10.1097/FJC.0000000000000246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503374PMC
July 2015

Lebanese medical students' intention to deliver smoking cessation advice.

J Epidemiol Glob Health 2015 Jun 6;5(2):117-23. Epub 2014 Sep 6.

College of Public Health and Health Informatics, King Saud Bin Abdulaziz University for Health Sciences, National Guard Health Affairs, King Abdulaziz Medical City, P.O. Box 22490, Mail Code 2350, Riyadh 11426, Saudi Arabia.

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http://dx.doi.org/10.1016/j.jegh.2014.05.003DOI Listing
June 2015

Use of whole exome sequencing for the identification of Ito-based arrhythmia mechanism and therapy.

J Am Heart Assoc 2015 May 26;4(5). Epub 2015 May 26.

The Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University Wexner Medical Center, The Ohio State University College of Engineering, Columbus, OH (A.C.S., C.F.K., P.G., B.L.J., J.C., A.K., R.D.H., P.F.B., P.L.J., R.W., S.V.R., T.J.H., C.A.C., P.J.M.) Department of Internal Medicine, The Ohio State University Wexner Medical Center, The Ohio State University College of Engineering, Columbus, OH (A.C.S., P.F.B., R.W., S.V.R., T.J.H., P.J.M.) Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, The Ohio State University College of Engineering, Columbus, OH (C.F.K., J.C., P.L.J., P.J.M.).

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http://dx.doi.org/10.1161/JAHA.114.001762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599408PMC
May 2015

Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia.

Circulation 2015 Feb 28;131(8):695-708. Epub 2015 Jan 28.

From Dorothy M. Davis Heart and Lung Research Institute (S.A.S., A.C.S., J.C., C.F.K., S.C.L., I.M.B., V.P.L., M.M., I.P., L.D.H., T.R.W., P.W., R.W., P.F.B., P.M.J., A.K., R.S.H., M.S., J.M., C.A.C., T.J.H., P.J.M.), Department of Internal Medicine, Division of Cardiovascular Medicine (S.A.S., R.W., P.F.B., P.J.M.), Department of Internal Medicine, Division of Human Genetics (A.C.S., P.M.J.), Department of Physiology and Cell Biology (J.C., C.F.K., S.C.L., M.M., I.P., L.D.H., T.R.W., P.W., P.M.J., P.J.M.), and Department of Surgery (A.K., R.S.H., M.S., J.M.), The Ohio State University Wexner Medical Center; Columbus; College of Pharmacy (I.M.B., V.P.L., C.A.C.) and Department of Biomedical Engineering, College of Engineering (T.J.H.), The Ohio State University, Columbus; Division of Life Science and Institute for Advanced Study, Hong Kong University of Science and Technology, Clear Water Bay Kowloon, Hong Kong (Z.W., M.Z.); Department of Biology, South University of Science and Technology of China, Shenzhen, Guangdong, China (Z.W.); Institute of Pharmacology, Faculty of Medicine, University Duisburg-Essen, Essen, Germany (N.V., D.D.); Krannert Institute of Cardiology and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis (D.B., K.G.S., M.V.); and Department of Neuroscience, Baylor College of Medicine; Houston, TX (C.Z., M.N.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342332PMC
February 2015

The impact of insurance and socioeconomic status on outcomes for patients with left ventricular assist devices.

J Surg Res 2014 Oct 9;191(2):302-8. Epub 2014 May 9.

The Ohio State University College of Public Health, Columbus, Ohio; Division of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio.

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http://dx.doi.org/10.1016/j.jss.2014.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160377PMC
October 2014

β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart.

Cardiovasc Res 2014 Apr 20;102(1):166-75. Epub 2014 Jan 20.

The Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, 473 W. 12th Avenue, 43210 Columbus, OH, USA.

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http://dx.doi.org/10.1093/cvr/cvu008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958619PMC
April 2014

Tobacco dependence curricula in Middle Eastern and North African medical education.

Tob Control 2013 Nov 25;22(6):427-8. Epub 2012 Aug 25.

College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1136/tobaccocontrol-2012-050500DOI Listing
November 2013

Mentorship in an academic medical center.

Am J Med 2013 Nov 24;126(11):1022-5. Epub 2013 Sep 24.

The Center for Faculty Advancement Mentoring and Engagement, The Ohio State University College of Medicine, Columbus. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2013.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976603PMC
November 2013

Statin pharmacogenomics: pursuing biomarkers for predicting clinical outcomes.

Discov Med 2013 Aug;16(86):45-51

College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039562PMC
August 2013

Feasibility of using multivector impedance to monitor pulmonary congestion in heart failure patients.

J Interv Card Electrophysiol 2012 Nov 12;35(2):197-206. Epub 2012 Jun 12.

Division of Cardiovascular Medicine, College of Medicine, College of Public Health, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s10840-012-9693-2DOI Listing
November 2012

The role of repeat transesophageal echocardiography in patients without atrial thrombus prior to cardioversion or ablation.

J Am Soc Echocardiogr 2012 Oct 29;25(10):1106-12. Epub 2012 Jun 29.

The Ohio State University, Division of CardiovascularMedicine, 473 West 12th Avenue,Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.echo.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742543PMC
October 2012

A new Era in the natural history of dilated cardiomyopathy.

Authors:
Philip F Binkley

J Am Coll Cardiol 2012 Feb;59(8):776; author reply 776-7

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http://dx.doi.org/10.1016/j.jacc.2011.09.070DOI Listing
February 2012

Selecting a mentor: a guide for residents, fellows, and young physicians.

Am J Med 2011 Oct;124(10):893-5

Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University College of Medicine and Public Health, Columbus, USA.

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http://dx.doi.org/10.1016/j.amjmed.2011.04.031DOI Listing
October 2011

Preface: depression and heart failure.

Heart Fail Clin 2011 Jan;7(1):xix-xx

Division of Cardiovascular Medicine, The Ohio State University College of Medicine, The Ohio State University College of Public Health, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.hfc.2010.09.001DOI Listing
January 2011

Mind-body medicine in chronic heart failure: a translational science challenge.

Circ Heart Fail 2010 Nov;3(6):715-25

The Ohio State University Division of Cardiovascular Medicine and the Dorothy Davis Heart and Lung Research Institute, 473 W 12th Ave, Columbus, OH 43210-1252, USA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.110.951509DOI Listing
November 2010

Regression of normalized left ventricular systolic function after discontinuation of treatment in patients with dilated cardiomyopathy.

Congest Heart Fail 2009 Sep-Oct;15(5):245-6

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, 43210, USA.

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http://dx.doi.org/10.1111/j.1751-7133.2009.00088.xDOI Listing
September 2010

Latent development of occlusive coronary atherosclerosis as a cause of decompensation of non-ischemic dilated cardiomyopathy.

Cardiology 2009 26;112(1):69-73. Epub 2008 Jun 26.

Division of Cardiovascular Medicine, Ohio State University College of Medicine and Public Health, Columbus, Ohio, USA.

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http://dx.doi.org/10.1159/000137703DOI Listing
March 2009

Claudin-5 levels are reduced in human end-stage cardiomyopathy.

J Mol Cell Cardiol 2008 Jul 25;45(1):81-7. Epub 2008 Apr 25.

Department of Molecular and Cellular Biochemistry, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2008.04.005DOI Listing
July 2008

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.

Circulation 2008 Mar 3;117(11):1414-22. Epub 2008 Mar 3.

Department of Molecular Virology, Immunology, and Molecular Genetics, Ohio State University, Columbus, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.759233DOI Listing
March 2008

Recovery of normal ventricular function in patients with dilated cardiomyopathy: predictors of an increasingly prevalent clinical event.

Am Heart J 2008 Jan 27;155(1):69-74. Epub 2007 Sep 27.

The Division of Cardiovascular Medicine and the Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210-1282, USA.

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http://dx.doi.org/10.1016/j.ahj.2007.08.010DOI Listing
January 2008

Endothelial nitric oxide synthase gene: prospects for treatment of heart disease.

Pharmacogenomics 2007 Dec;8(12):1723-34

The Ohio State University, Division of Cardiovascular Medicine and Davis Heart and Lung Research Institute, Department of Medicine, 235 DHLRI, 473 W 12th Avenue, Columbus, Ohio 43210-1252, USA.

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http://dx.doi.org/10.2217/14622416.8.12.1723DOI Listing
December 2007

Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues.

Pharmacogenet Genomics 2006 Oct;16(10):735-45

Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1097/01.fpc.0000230119.34205.8aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688811PMC
October 2006

Navigating the crossroads of coronary artery disease and heart failure.

Circulation 2006 Sep;114(11):1202-13

Northwestern University Feinberg School of Medicine, Galter 10-240, 201 E Huron St, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.623199DOI Listing
September 2006

Sustained restoration of autonomic balance with long- but not short-acting metoprolol in patients with heart failure.

J Card Fail 2006 Apr;12(3):171-6

Department of Pharmacy Practice, University of Florida College of Pharmacy, Gainesville, 32610, USA.

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http://dx.doi.org/10.1016/j.cardfail.2005.12.002DOI Listing
April 2006

Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination.

J Am Coll Cardiol 2006 Feb 18;47(3):541-6. Epub 2006 Jan 18.

Davis Heart and Lung Research Institute and Division of Cardiovascular Medicine, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio 43210-1252, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S073510970502625
Publisher Site
http://dx.doi.org/10.1016/j.jacc.2005.09.034DOI Listing
February 2006

Psychological distress and cardiovascular disease: results from the 2002 National Health Interview Survey.

Eur Heart J 2005 Sep 9;26(18):1923-9. Epub 2005 Jun 9.

Division of Epidemiology and Biostatistics, The Ohio State University School of Public Health, B-116 Starling-Loving Hall, 320 West 10th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1093/eurheartj/ehi329DOI Listing
September 2005

Depressive symptoms and inflammation among heart failure patients.

Am Heart J 2005 Jul;150(1):132-6

Division of Epidemiology and Biostatistics, The Ohio State University College of Medicine and Public Health, School of Public Health, Columbus, Ohio, USA.

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http://dx.doi.org/10.1016/j.ahj.2004.08.029DOI Listing
July 2005

A polymorphism of the gene encoding AMPD1: clinical impact and proposed mechanisms in congestive heart failure.

Congest Heart Fail 2004 Nov-Dec;10(6):274-78; quiz 279-80

Dorothy M. Davis Heart and Lung Research Institute and the Division of Cardiovascular Diseases, Ohio State University, Columbus, OH 43210, USA.

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February 2005

A polymorphism of the endothelial nitric oxide synthase promoter is associated with an increase in autonomic imbalance in patients with congestive heart failure.

Am Heart J 2005 Feb;149(2):342-8

Division of Cardiovascular Medicine, Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1016/j.ahj.2004.05.059DOI Listing
February 2005

The next era of examination and management of the patient with cardiovascular disease.

Authors:
Philip F Binkley

IEEE Eng Med Biol Mag 2003 May-Jun;22(3):23-4

Ohio State University, Division of Cardiovascular Medicine, Heart & Lung Research Institute, USA.

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September 2003

Stem cell-derived cardiomyocytes demonstrate arrhythmic potential.

Circulation 2003 May;107(20):e195; author reply e195

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http://dx.doi.org/10.1161/01.CIR.0000074252.74409.E5DOI Listing
May 2003

Pathophysiology of plaque instability: insights at the genomic level.

Prog Cardiovasc Dis 2002 Mar-Apr;44(5):323-38

Division of Cardiology, Department of Medicine, Cardiovascular Center For Genomic Science, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1053/pcad.2002.125097DOI Listing
June 2002