Dr Philip E Dubé, PhD - Children's Hospital Los Angeles

Dr Philip E Dubé

PhD

Children's Hospital Los Angeles

Los Angeles, CA | United States

Main Specialties: Biology

Additional Specialties: Mucosal Immunology, Inflammatory Bowel Disease, Epithelial Biology, Cell Biology, Inflammation, Cancer

Dr Philip E Dubé, PhD - Children's Hospital Los Angeles

Dr Philip E Dubé

PhD

Introduction

Primary Affiliation: Children's Hospital Los Angeles - Los Angeles, CA , United States

Specialties:

Additional Specialties:

Publications

12Publications

164Reads

-Profile Views

196PubMed Central Citations

Tumor Necrosis Factor Receptor 2 Restricts the Pathogenicity of CD8(+) T Cells in Mice With Colitis.

Gastroenterology 2015 Oct 11;149(4):993-1005.e2. Epub 2015 Jun 11.

The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California; Department of Pediatrics, Children's Hospital Los Angeles, California; Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841683PMC
October 2015
5 Reads
7 Citations
16.720 Impact Factor

Optical reconstruction of murine colorectal mucosa at cellular resolution.

Am J Physiol Gastrointest Liver Physiol 2015 May 26;308(9):G721-35. Epub 2015 Feb 26.

The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California; Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California; and Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, California

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http://ajpgi.physiology.org/content/ajpgi/early/2015/02/20/a
Web Search
http://ajpgi.physiology.org/content/ajpgi/308/9/G721.full.pd
Web Search
http://ajpgi.physiology.org/lookup/doi/10.1152/ajpgi.00310.2
Publisher Site
http://dx.doi.org/10.1152/ajpgi.00310.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421015PMC
May 2015
16 Reads
2 Citations
3.800 Impact Factor

Redeeming an old foe: protective as well as pathophysiological roles for tumor necrosis factor in inflammatory bowel disease.

Am J Physiol Gastrointest Liver Physiol 2015 Feb 4;308(3):G161-70. Epub 2014 Dec 4.

Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California; Department of Pediatrics, Children's Hospital Los Angeles and University of Southern California Keck School of Medicine, Los Angeles, California; and Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, California

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http://dx.doi.org/10.1152/ajpgi.00142.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312954PMC
February 2015
4 Reads
6 Citations
3.800 Impact Factor

Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.

J Immunol 2014 Feb 3;192(3):1013-23. Epub 2014 Jan 3.

Department of Breast Cancer Medical Oncology, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin 300060, P. R. China;

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http://dx.doi.org/10.4049/jimmunol.1300133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006992PMC
February 2014
56 Reads
20 Citations
4.922 Impact Factor

Epidermal growth factor receptor inhibits colitis-associated cancer in mice.

J Clin Invest 2012 Aug 9;122(8):2780-92. Epub 2012 Jul 9.

The Saban Research Institute of Children’s Hospital Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1172/JCI62888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408743PMC
August 2012
15 Reads
25 Citations
13.215 Impact Factor

ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival.

Lab Invest 2012 Mar 12;92(3):437-50. Epub 2011 Dec 12.

Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1038/labinvest.2011.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289719PMC
March 2012
15 Reads
11 Citations
3.680 Impact Factor

Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts.

Endocrinology 2011 Feb 15;152(2):436-46. Epub 2010 Dec 15.

Department of Physiology,University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1210/en.2010-0822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384785PMC
February 2011
15 Reads
12 Citations
4.503 Impact Factor

Glucagon-like peptide-2 activates beta-catenin signaling in the mouse intestinal crypt: role of insulin-like growth factor-I.

Endocrinology 2008 Jan 20;149(1):291-301. Epub 2007 Sep 20.

Department of Physiology, University of Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1210/en.2007-0561DOI Listing
January 2008
8 Reads
18 Citations
4.503 Impact Factor

Frontiers in glucagon-like peptide-2: multiple actions, multiple mediators.

Am J Physiol Endocrinol Metab 2007 Aug 24;293(2):E460-5. Epub 2007 Jul 24.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1152/ajpendo.00149.2007DOI Listing
August 2007
2 Reads
36 Citations
3.790 Impact Factor

The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice.

Gastroenterology 2006 Aug;131(2):589-605

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2006.05.055DOI Listing
August 2006
4 Reads
36 Citations
16.720 Impact Factor

PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AMP.

FEBS J 2005 Jun;272(11):2746-59

Division of Cell and Molecular Biology, Toronto General Research Institute, University Health Network, Toronto, Ontario.

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http://dx.doi.org/10.1111/j.1742-4658.2005.04694.xDOI Listing
June 2005
23 Reads
7 Citations
4.001 Impact Factor

Nutrient, neural and endocrine control of glucagon-like peptide secretion.

Horm Metab Res 2004 Nov-Dec;36(11-12):755-60

Department of Physiology, University of Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1055/s-2004-826159DOI Listing
May 2005
1 Read
16 Citations
2.121 Impact Factor