Philip D Gregory

Philip D Gregory

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Philip D Gregory

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Sticky collisions of ultracold RbCs molecules.

Nat Commun 2019 Jul 15;10(1):3104. Epub 2019 Jul 15.

Joint Quantum Centre (JQC), Durham-Newcastle, Department of Physics, Durham University, Durham, DH1 3LE, UK.

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http://dx.doi.org/10.1038/s41467-019-11033-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629645PMC
July 2019

Production of Ultracold Rb Cs in the Absolute Ground State: Complete Characterisation of the Stimulated Raman Adiabatic Passage Transfer.

Chemphyschem 2016 Nov 11;17(22):3811-3817. Epub 2016 Oct 11.

Joint Quantum Centre (JQC) Durham-Newcastle, Department of Physics, Durham University, South Road, Durham, DH1 3LE, UK.

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http://dx.doi.org/10.1002/cphc.201600501DOI Listing
November 2016

Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model.

Mol Ther 2016 Feb 27;24(2):342-353. Epub 2015 Oct 27.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Parque Tecnológico Ciencias de la Salud, Granada, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163033
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http://dx.doi.org/10.1038/mt.2015.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817813PMC
February 2016

Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.

Nat Biotechnol 2015 Dec 9;33(12):1256-1263. Epub 2015 Nov 9.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nbt.3408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842001PMC
December 2015

Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation.

Mol Ther Methods Clin Dev 2015 14;1:14057. Epub 2015 Jan 14.

Division of Medical Genetics, University of Washington , Seattle, Washington, USA ; Department of Pathology, University of Washington , Seattle, Washington, USA.

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http://dx.doi.org/10.1038/mtm.2014.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448996PMC
June 2015

Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.

Blood 2015 Apr 2;125(17):2597-604. Epub 2015 Mar 2.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA; Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, University of California, Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1182/blood-2014-12-615948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408287PMC
April 2015

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates.

Science 2015 Jan 11;347(6220):428-31. Epub 2014 Dec 11.

Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY, USA. Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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http://dx.doi.org/10.1126/science.1260867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349400PMC
January 2015

Creation of ultracold ^{87}Rb^{133}Cs molecules in the rovibrational ground state.

Phys Rev Lett 2014 Dec 17;113(25):255301. Epub 2014 Dec 17.

Department of Physics, Joint Quantum Centre (JQC) Durham-Newcastle, Durham University, South Road, Durham DH1 3LE, United Kingdom.

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http://dx.doi.org/10.1103/PhysRevLett.113.255301DOI Listing
December 2014

A southern blot protocol to detect chimeric nuclease-mediated gene repair.

Methods Mol Biol 2014 ;1114:325-38

School of Biological Sciences, Royal Holloway-University of London, Egham, Surrey, UK.

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http://dx.doi.org/10.1007/978-1-62703-761-7_21DOI Listing
October 2014

Reactivation of developmentally silenced globin genes by forced chromatin looping.

Cell 2014 Aug;158(4):849-860

Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.05.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134511PMC
August 2014

Targeted gene therapy and cell reprogramming in Fanconi anemia.

EMBO Mol Med 2014 Jun 6;6(6):835-48. Epub 2014 Apr 6.

Division of Hematopoietic Innovative Therapies, CIEMAT/CIBERER, Madrid, Spain Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Madrid, Spain

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http://dx.doi.org/10.15252/emmm.201303374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203359PMC
June 2014

CRISPR technology for gene therapy.

Nat Med 2014 May;20(5):476-7

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http://dx.doi.org/10.1038/nm.3566DOI Listing
May 2014

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV.

N Engl J Med 2014 Mar;370(10):901-10

From the Perelman School of Medicine, University of Pennsylvania, Philadelphia (P.T., I.F., M.K., R.G.C., G.B.-S., G.P., W.-T.H., B.L.L., C.H.J.); Albert Einstein College of Medicine, Bronx, NY (D.S.); and Sangamo BioSciences, Richmond, CA (W.W.T., S.Q.W., G.L., S.K.S., R.T.S., M.A.G., G.N., M.C.H., P.D.G., D.G.A.).

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http://www.nejm.org/doi/10.1056/NEJMoa1300662
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http://dx.doi.org/10.1056/NEJMoa1300662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084652PMC
March 2014

Robust ZFN-mediated genome editing in adult hemophilic mice.

Blood 2013 Nov 1;122(19):3283-7. Epub 2013 Oct 1.

Division of Hematology and Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA;

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http://dx.doi.org/10.1182/blood-2013-04-497354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821724PMC
November 2013

Translating dosage compensation to trisomy 21.

Nature 2013 Aug 17;500(7462):296-300. Epub 2013 Jul 17.

Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA.

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http://dx.doi.org/10.1038/nature12394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848249PMC
August 2013

In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration.

Biotechnol Bioeng 2013 Mar 23;110(3):871-80. Epub 2012 Oct 23.

Sangamo BioSciences, Richmond, California 94804, USA.

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http://dx.doi.org/10.1002/bit.24733DOI Listing
March 2013

Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome.

Dis Model Mech 2013 Mar 11;6(2):544-54. Epub 2013 Jan 11.

Human DNA Variability Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Parque Tecnológico Ciencias de la Salud, Av. de la Ilustracion 114, 18007 Granada, Spain.

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http://dx.doi.org/10.1242/dmm.010652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597037PMC
March 2013

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.

Nat Methods 2012 Oct 26;9(10):993-8. Epub 2012 Aug 26.

Department of Microbiology & Immunology, Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1038/nmeth.2143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697006PMC
October 2012

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer.

Nat Med 2012 May;18(5):807-815

Experimental Hematology Unit, Division of Regenerative Medicine, Gene Therapy and Stem Cells, Program of Immunology, Gene Therapy and Bio-Immunotherapy of Cancer, Leukemia Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1038/nm.2700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019824PMC
May 2012

Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.

Mol Ther 2012 Apr 24;20(4):849-59. Epub 2012 Jan 24.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/mt.2011.310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321595PMC
April 2012

Targeted genome editing across species using ZFNs and TALENs.

Science 2011 Jul 23;333(6040):307. Epub 2011 Jun 23.

Howard Hughes Medical Institute (HHMI), Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3204, USA.

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http://dx.doi.org/10.1126/science.1207773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489282PMC
July 2011

Genome editing with engineered zinc finger nucleases.

Nat Rev Genet 2010 Sep;11(9):636-46

Sangamo BioSciences Inc., Richmond, California 94804, USA.

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http://dx.doi.org/10.1038/nrg2842DOI Listing
September 2010

Transient cold shock enhances zinc-finger nuclease-mediated gene disruption.

Nat Methods 2010 Jun 2;7(6):459-60. Epub 2010 May 2.

Sangamo BioSciences, Richmond, California, USA.

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http://dx.doi.org/10.1038/nmeth.1456DOI Listing
June 2010

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.

Biotechnol Bioeng 2010 May;106(1):97-105

Sangamo BioSciences, Inc., Point Richmond Tech Center, 501 Canal Blvd, Suite A100, Richmond, California 94804, USA.

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http://dx.doi.org/10.1002/bit.22654DOI Listing
May 2010

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases.

Nat Biotechnol 2008 Jun 25;26(6):702-8. Epub 2008 May 25.

Sangamo BioSciences, Inc., Pt. Richmond Tech Center, 501 Canal Blvd., Suite A100, Richmond, California 94804, USA.

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http://dx.doi.org/10.1038/nbt1409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674762PMC
June 2008

Gene transfer of an engineered zinc finger protein enhances the anti-angiogenic defense system.

Mol Ther 2007 Nov 14;15(11):1917-23. Epub 2007 Aug 14.

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-9277, USA.

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http://dx.doi.org/10.1038/sj.mt.6300280DOI Listing
November 2007

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery.

Nat Biotechnol 2007 Nov 28;25(11):1298-306. Epub 2007 Oct 28.

San Raffaele Telethon Institute for Gene Therapy, via Olgettina, 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1038/nbt1353DOI Listing
November 2007

Ocular gene transfer with self-complementary AAV vectors.

Invest Ophthalmol Vis Sci 2007 Jul;48(7):3324-8

Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-9277, USA.

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http://dx.doi.org/10.1167/iovs.06-1306DOI Listing
July 2007

An improved zinc-finger nuclease architecture for highly specific genome editing.

Nat Biotechnol 2007 Jul 1;25(7):778-85. Epub 2007 Jul 1.

Sangamo BioSciences, Inc., Pt. Richmond Tech Center, 501 Canal Blvd., Suite A100 Richmond, California 94804, USA.

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http://dx.doi.org/10.1038/nbt1319DOI Listing
July 2007

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases.

Proc Natl Acad Sci U S A 2007 Feb 20;104(9):3055-60. Epub 2007 Feb 20.

Sangamo BioSciences, Inc., Point Richmond Technology Center, 501 Canal Boulevard, Suite A100, Richmond, CA 94804, USA.

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http://dx.doi.org/10.1073/pnas.0611478104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802009PMC
February 2007

Controlling gene expression in Drosophila using engineered zinc finger protein transcription factors.

Biochem Biophys Res Commun 2006 Sep 31;348(3):873-9. Epub 2006 Jul 31.

Sangamo BioSciences, Inc., Point Richmond Tech Center, 501, Canal Blvd., Suite A100, Richmond, CA 94804, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.07.137DOI Listing
September 2006

Highly efficient endogenous human gene correction using designed zinc-finger nucleases.

Nature 2005 Jun 3;435(7042):646-51. Epub 2005 Apr 3.

Sangamo BioSciences, Inc., Pt. Richmond Tech Center 501, Canal Blvd, Suite A100 Richmond, California 94804, USA.

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http://dx.doi.org/10.1038/nature03556DOI Listing
June 2005

Histone deimination antagonizes arginine methylation.

Cell 2004 Sep;118(5):545-53

Gurdon Institute and Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom.

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http://dx.doi.org/10.1016/j.cell.2004.08.020DOI Listing
September 2004

Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo.

Curr Biol 2002 Dec;12(24):2159-66

Sangamo BioSciences, Point Richmond Tech Center, 501 Canal Boulevard, Suite A100, Richmond, California 94804, USA.

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http://dx.doi.org/10.1016/s0960-9822(02)01391-xDOI Listing
December 2002

Biotechnologies and therapeutics: chromatin as a target.

Curr Opin Genet Dev 2002 Apr;12(2):233-42

Sangamo Biosciences, Pt Richmond Tech Center, 501 Canal Blvd, Suite A100, Richmond, California 94804, USA.

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http://dx.doi.org/10.1016/s0959-437x(02)00291-5DOI Listing
April 2002