Publications by authors named "Philip A Barker"

85Publications

NGF- and BDNF-dependent DRG sensory neurons deploy distinct degenerative signaling mechanisms.

Authors:
Andrés de León Julien Gibon Philip A Barker

eNeuro 2020 Dec 16. Epub 2020 Dec 16.

Department of Biology, University of British Columbia Okanagan, Kelowna, British Columbia V1V 1V7, Canada

View Article and Find Full Text PDF
December 2020

Nerve Growth Factor Signaling and Its Contribution to Pain.

Authors:
Philip A Barker Patrick Mantyh Lars Arendt-Nielsen Lars Viktrup Leslie Tive

J Pain Res 2020 26;13:1223-1241. Epub 2020 May 26.

Pfizer, Inc, New York, NY, USA.

View Article and Find Full Text PDF
May 2020

Collapsin Response Mediator Protein 4 (CRMP4) Facilitates Wallerian Degeneration and Axon Regeneration following Sciatic Nerve Injury.

Authors:
Marie-Pier Girouard Tristan Simas Luyang Hua Barbara Morquette Mohamad R Khazaei Nicolas Unsain Aaron D Johnstone Isabel Rambaldi Ricardo L Sanz Marie-Eve Di Raddo Kanchana K Gamage Yu Yong Dianna E Willis Valerie M K Verge Philip A Barker Christopher Deppmann Alyson E Fournier

eNeuro 2020 Mar/Apr;7(2). Epub 2020 Mar 2.

Department of Neurology and Neurosurgery, Montréal Neurological Institute and Hospital, Montréal, Québec H3A 2B4, Canada

View Article and Find Full Text PDF
March 2020

Developmental Axon Degeneration Requires TRPV1-Dependent Ca Influx.

Authors:
Aaron D Johnstone Andrés de Léon Nicolás Unsain Julien Gibon Philip A Barker

eNeuro 2019 Jan-Feb;6(1). Epub 2019 Feb 27.

Department of Biology, University of British Columbia Okanagan, Kelowna, British Columbia V1V 1V7, Canada.

View Article and Find Full Text PDF
May 2019

The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons.

Authors:
Rhalena A Thomas Julien Gibon Carol X Q Chen Sabrina Chierzi Vincent G Soubannier Stephanie Baulac Philippe Séguéla Keith Murai Philip A Barker

eNeuro 2018 Jul-Aug;5(4). Epub 2018 Sep 7.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec H3A 2B4, Canada.

View Article and Find Full Text PDF
March 2019

A novel method for quantifying axon degeneration.

Authors:
Aaron D Johnstone Robin M Hallett Andrés de Léon Bruno Carturan Julien Gibon Philip A Barker

PLoS One 2018 18;13(7):e0199570. Epub 2018 Jul 18.

Department of Biology, University of British Columbia Okanagan, Kelowna, British Columbia, Canada.

View Article and Find Full Text PDF
December 2018

Author Correction: Remodeling of the Actin/Spectrin Membrane-associated Periodic Skeleton, Growth Cone Collapse and F-Actin Decrease during Axonal Degeneration.

Authors:
Nicolas Unsain Martin D Bordenave Gaby F Martinez Sami Jalil Catalina von Bilderling Federico M Barabas Luciano A Masullo Aaron D Johnstone Philip A Barker Mariano Bisbal Fernando D Stefani Alfredo O Cáceres

Sci Rep 2018 Apr 12;8(1):6002. Epub 2018 Apr 12.

Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), UNC, Friuli, 2434 - 5016, Córdoba, Argentina.

View Article and Find Full Text PDF
April 2018

Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat.

Authors:
Léa Décarie-Spain Sandeep Sharma Cécile Hryhorczuk Victor Issa-Garcia Philip A Barker Nathalie Arbour Thierry Alquier Stephanie Fulton

Mol Metab 2018 04 31;10:1-13. Epub 2018 Jan 31.

Centre de Recherche du CHUM, Université de Montréal, Quebec, Canada; Montreal Diabetes Research Centre, Université de Montréal, Quebec, Canada; Department of Nutrition, Université de Montréal, Quebec, Canada. Electronic address:

View Article and Find Full Text PDF
April 2018

Remodeling of the Actin/Spectrin Membrane-associated Periodic Skeleton, Growth Cone Collapse and F-Actin Decrease during Axonal Degeneration.

Authors:
Nicolas Unsain Martin D Bordenave Gaby F Martinez Sami Jalil Catalina von Bilderling Federico M Barabas Luciano A Masullo Aaron D Johnstone Philip A Barker Mariano Bisbal Fernando D Stefani Alfredo O Cáceres

Sci Rep 2018 02 14;8(1):3007. Epub 2018 Feb 14.

Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), UNC, Friuli, 2434 - 5016, Córdoba, Argentina.

View Article and Find Full Text PDF
February 2018

Neurotrophins and Proneurotrophins: Focus on Synaptic Activity and Plasticity in the Brain.

Authors:
Julien Gibon Philip A Barker

Neuroscientist 2017 12 17;23(6):587-604. Epub 2017 Mar 17.

1 Department of Biology, University of British Columbia, Kelowna, BC, Canada.

View Article and Find Full Text PDF
December 2017

Generation and characterization of mice bearing null alleles of nradd/Nrh2.

Authors:
Nicolas Unsain Genevieve Dorval Jae Hyung Sheen Philip A Barker

Genesis 2016 Dec 12;54(12):605-612. Epub 2016 Nov 12.

Vice Principal Research University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna, British Columbia, V1V1V7, Canada.

View Article and Find Full Text PDF
December 2016

Interpretation and application of carbon isotope ratios in freshwater diatom silica.

Authors:
Megan Webb Philip A Barker Peter M Wynn Oliver Heiri Maarten van Hardenbroek Frances Pick James M Russell Andy W Stott Melanie J Leng

J Quat Sci 2016 May 17;31(4):300-309. Epub 2016 Jun 17.

NERC Isotope Geosciences FacilitiesBritish Geological SurveyNottinghamUK; Centre for Environmental GeochemistrySchool of GeographyUniversity of NottinghamNottinghamUK.

View Article and Find Full Text PDF
May 2016

Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile.

Authors:
Julien Gibon Min Su Kang Arturo Aliaga Behrang Sharif Pedro Rosa-Neto Philippe Séguéla Philip A Barker Alexey Kostikov

Bioorg Med Chem 2016 10 13;24(19):4759-4765. Epub 2016 Aug 13.

Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, QC H3A2B4, Canada. Electronic address:

View Article and Find Full Text PDF
October 2016

Identification of genetic variants of LGI1 and RTN4R (NgR1) linked to schizophrenia that are defective in NgR1-LGI1 signaling.

Authors:
Rhalena A Thomas Amirthagowri Ambalavanan Guy A Rouleau Philip A Barker

Mol Genet Genomic Med 2016 Jul 11;4(4):447-56. Epub 2016 Mar 11.

Department of Neurology and NeurosurgeryMontreal Neurological InstituteMcGill University3801 UniversityMontrealQuebecH3A 2B4Canada; Department of BiologyUniversity of British ColumbiaKelownaBC. V1V 1V7Canada.

View Article and Find Full Text PDF
July 2016

Calpain-dependent truncated form of TrkB-FL increases in neurodegenerative processes.

Authors:
Víctor Danelon Laura E Montroull Nicolás Unsain Philip A Barker Daniel H Mascó

Mol Cell Neurosci 2016 09 20;75:81-92. Epub 2016 Jul 20.

Laboratorio de Neurobiología, Instituto de Investigaciones Biológicas y Tecnológicas, IIByT-CONICET-FCEFyN, Universidad Nacional de Córdoba, Av. Vélez Sarsfield 1611, Córdoba, Argentina. Electronic address:

View Article and Find Full Text PDF
September 2016

The X-linked inhibitor of apoptosis regulates long-term depression and learning rate.

Authors:
Julien Gibon Nicolas Unsain Karine Gamache Rhalena A Thomas Andres De Leon Aaron Johnstone Karim Nader Philippe Séguéla Philip A Barker

FASEB J 2016 09 17;30(9):3083-90. Epub 2016 May 17.

Biology Unit, University of British Columbia, Okanagan Campus, Kelowna, British Columbia, Canada; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada;

View Article and Find Full Text PDF
September 2016

North Atlantic forcing of moisture delivery to Europe throughout the Holocene.

Authors:
Andrew C Smith Peter M Wynn Philip A Barker Melanie J Leng Stephen R Noble Wlodek Tych

Sci Rep 2016 04 25;6:24745. Epub 2016 Apr 25.

Lancaster Environment Centre, Lancaster University, Lancaster, LA1 4YQ, UK.

View Article and Find Full Text PDF
April 2016

HBpF-proBDNF: A New Tool for the Analysis of Pro-Brain Derived Neurotrophic Factor Receptor Signaling and Cell Biology.

Authors:
Perrine Gaub Andrès de Léon Julien Gibon Vincent Soubannier Geneviève Dorval Philippe Séguéla Philip A Barker

PLoS One 2016 7;11(3):e0150601. Epub 2016 Mar 7.

Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, H3A 2B4, Canada.

View Article and Find Full Text PDF
August 2016

Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex.

Authors:
Julien Gibon Philip A Barker Philippe Séguéla

Mol Brain 2016 Mar 1;9:23. Epub 2016 Mar 1.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Suite 778, Montreal, Quebec, H3A 2B4, Canada.

View Article and Find Full Text PDF
March 2016

An experiment to assess the effects of diatom dissolution on oxygen isotope ratios.

Authors:
Andrew C Smith Melanie J Leng George E A Swann Philip A Barker Anson W Mackay David B Ryves Hilary J Sloane Simon R N Chenery Mike Hems

Rapid Commun Mass Spectrom 2016 Jan;30(2):293-300

Department of Geology, University of Leicester, Leicester, LE1 7RH, UK.

View Article and Find Full Text PDF
January 2016