Publications by authors named "Peter Valent"

100Publications

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.

Nat Med 2020 Aug 3. Epub 2020 Aug 3.

Computational Oncology Service, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41591-020-1008-zDOI Listing
August 2020

Cell-based and antibody-mediated immunotherapies directed against leukemic stem cells in acute myeloid leukemia: Perspectives and open issues.

Stem Cells Transl Med 2020 Jul 13. Epub 2020 Jul 13.

Ludwig Boltzmann Institute for Hematology & Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/sctm.20-0147DOI Listing
July 2020

Oligo-monocytic CMML and other pre-CMML states: Clinical impact, prognostication and management.

Authors:
Peter Valent

Best Pract Res Clin Haematol 2020 06 15;33(2):101137. Epub 2019 Dec 15.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Hematology & Oncology, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2019.101137DOI Listing
June 2020

Midostaurin improves quality of life and mediator-related symptoms in advanced systemic mastocytosis.

J Allergy Clin Immunol 2020 Aug 11;146(2):356-366.e4. Epub 2020 May 11.

University Medical Center Groningen, Department of Hematology, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2020.03.044DOI Listing
August 2020

Microarray-Based Detection of Allergen-Reactive IgE in Patients with Mastocytosis.

J Allergy Clin Immunol Pract 2020 Apr 26. Epub 2020 Apr 26.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.04.030DOI Listing
April 2020

Activation of Siglec-7 results in inhibition of in vitro and in vivo growth of human mast cell leukemia cells.

Pharmacol Res 2020 Aug 5;158:104682. Epub 2020 Feb 5.

Pharmacology & Experimental Therapeutics Unit, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2020.104682DOI Listing
August 2020

An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis.

J Cancer Res Clin Oncol 2020 Apr 24;146(4):945-951. Epub 2020 Jan 24.

Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00432-019-03119-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085471PMC
April 2020

KIT D816V and the cytokine storm in mastocytosis: production and role of interleukin-6.

Authors:
Peter Valent

Haematologica 2020 01;105(1):5-6

Department of Internal Medicine I, Division of Hematology and Hemostaseology

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http://dx.doi.org/10.3324/haematol.2019.234864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939527PMC
January 2020

CDK4/CDK6 inhibition as a novel strategy to suppress the growth and survival of BCR-ABL1+ clones in TKI-resistant CML.

EBioMedicine 2019 Dec 21;50:111-121. Epub 2019 Nov 21.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; Ludwig Boltzmann Institute for Hematology & Oncology, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921367PMC
December 2019

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML.

Int J Mol Sci 2019 Aug 29;20(17). Epub 2019 Aug 29.

Department of Internal Medicine V (Hematology & Oncology), Medical University of Innsbruck, 1090 Innsbruck, Austria.

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http://dx.doi.org/10.3390/ijms20174233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747233PMC
August 2019

Redistribution, homing and organ-invasion of neoplastic stem cells in myeloid neoplasms.

Semin Cancer Biol 2020 02 10;60:191-201. Epub 2019 Aug 10.

Institute of Anatomy and Experimental Morphology, University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2019.07.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115853PMC
February 2020

Effects of ibrutinib on proliferation and histamine release in canine neoplastic mast cells.

Vet Comp Oncol 2019 Dec 13;17(4):553-561. Epub 2019 Aug 13.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/vco.12520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900099PMC
December 2019

A hypoallergenic peptide mix containing T cell epitopes of the clinically relevant house dust mite allergens.

Allergy 2019 12 3;74(12):2461-2478. Epub 2019 Oct 3.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/all.13956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078969PMC
December 2019

Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches.

Int J Mol Sci 2019 Jun 18;20(12). Epub 2019 Jun 18.

Division of Allergy and Clinical Immunology, University of Salerno, 84131 Salerno, Italy.

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http://dx.doi.org/10.3390/ijms20122976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627900PMC
June 2019

Doctor, I Think I Am Suffering from MCAS: Differential Diagnosis and Separating Facts from Fiction.

J Allergy Clin Immunol Pract 2019 04;7(4):1109-1114

Division of Allergy and Clinical Immunology, University of Michigan, Ann Arbor, Mich.

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http://dx.doi.org/10.1016/j.jaip.2018.11.045DOI Listing
April 2019

A kinase profile-adapted drug combination elicits synergistic cooperative effects on leukemic cells carrying BCR-ABL1 in Ph+ CML.

Leuk Res 2019 03 28;78:36-44. Epub 2018 Dec 28.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834439PMC
March 2019

Additional prognostic impact of the percentage of erythroid cells in the bone marrow of patients with myelodysplastic syndromes.

Leuk Res 2019 02 28;77:8-13. Epub 2018 Dec 28.

University of Rochester Medical Center, Department of Pathology, Hematopathology Unit and James P. Wilmot Cancer Institute, Rochester, NY, USA.

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http://dx.doi.org/10.1016/j.leukres.2018.12.012DOI Listing
February 2019

Therapeutic Vulnerabilities in -Mutant AML Unmasked by Palbociclib.

Int J Mol Sci 2018 Dec 11;19(12). Epub 2018 Dec 11.

Institute of Pharmacology and Toxicology, University of Veterinary Medicine, 1210 Vienna, Austria.

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http://dx.doi.org/10.3390/ijms19123987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321303PMC
December 2018

Non-NAD-like PARP1 inhibitor enhanced synthetic lethal effect of NAD-like PARP inhibitors against BRCA1-deficient leukemia.

Leuk Lymphoma 2019 04 2;60(4):1098-1101. Epub 2018 Oct 2.

a Department of Microbiology and Immunology and Fels Institute for Cancer Research and Molecular Biology Lewis Katz School of Medicine , Temple University , Philadelphia , PA , USA.

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https://www.tandfonline.com/doi/full/10.1080/10428194.2018.1
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http://dx.doi.org/10.1080/10428194.2018.1520988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445778PMC
April 2019

The Mastocytosis Society Survey on Mast Cell Disorders: Part 2-Patient Clinical Experiences and Beyond.

J Allergy Clin Immunol Pract 2019 04 8;7(4):1157-1165.e6. Epub 2018 Aug 8.

Department of Internal Medicine, Division of Allergy and Clinical Immunology, University of Michigan, Ann Arbor, Mich. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.07.032DOI Listing
April 2019

The underestimated role of basophils in Ph chronic myeloid leukaemia.

Eur J Clin Invest 2018 Oct 6;48(10):e13000. Epub 2018 Aug 6.

LBPA CNRS UMR8113, Ecole Normale Supérieure de Paris Saclay, Cachan, France.

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http://dx.doi.org/10.1111/eci.13000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175372PMC
October 2018

ICUS, IDUS, CHIP and CCUS: Diagnostic Criteria, Separation from MDS and Clinical Implications.

Authors:
Peter Valent

Pathobiology 2019 1;86(1):30-38. Epub 2018 Jun 1.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna,

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https://www.karger.com/Article/FullText/489042
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http://dx.doi.org/10.1159/000489042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115849PMC
January 2019

Phenotyping and Target Expression Profiling of CD34/CD38 and CD34/CD38 Stem- and Progenitor cells in Acute Lymphoblastic Leukemia.

Neoplasia 2018 06 15;20(6):632-642. Epub 2018 May 15.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994777PMC
June 2018

Major response of PNH to an AML chemotherapy protocol.

Ann Hematol 2018 Aug 22;97(8):1487-1488. Epub 2018 Mar 22.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00277-018-3307-8DOI Listing
August 2018

Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas.

Expert Opin Ther Targets 2018 01 24;22(1):45-57. Epub 2017 Nov 24.

a Institute of Animal Breeding and Genetics , University of Veterinary Medicine Vienna , Vienna , Austria.

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http://dx.doi.org/10.1080/14728222.2018.1406924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743003PMC
January 2018

Anemia at older age: etiologies, clinical implications, and management.

Blood 2018 02 15;131(5):505-514. Epub 2017 Nov 15.

Department of Internal Medicine II (Infectious Diseases, Immunology, Rheumatology, Pneumology), Innsbruck Medical University, Innsbruck, Austria.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2017-07
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http://dx.doi.org/10.1182/blood-2017-07-746446DOI Listing
February 2018

Evaluation of cooperative antileukemic effects of nilotinib and vildagliptin in Ph chronic myeloid leukemia.

Exp Hematol 2018 01 12;57:50-59.e6. Epub 2017 Oct 12.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria; Institute of Laboratory Animal Science, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.exphem.2017.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115814PMC
January 2018

BCR-ABL1 compound mutants display differential and dose-dependent responses to ponatinib.

Haematologica 2018 01 5;103(1):e10-e12. Epub 2017 Oct 5.

Children's Cancer Research Institute, and Department of Pediatrics, Medical University of Vienna, Austria

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http://dx.doi.org/10.3324/haematol.2017.176347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777206PMC
January 2018

Peripheral arterial disease outcomes and association with suPAR: A bridge to myeloid precursors or mast cells or both?

Atherosclerosis 2017 09 8;264:77-78. Epub 2017 Jul 8.

Medical University of Vienna, Department of Medicine II, Division of Angiology, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.07.007DOI Listing
September 2017

Risk factors and mechanisms contributing to TKI-induced vascular events in patients with CML.

Leuk Res 2017 08 12;59:47-54. Epub 2017 May 12.

Medical Clinic III for Oncology, Haematology, Immunology and Rheumatology, University Hospital Bonn (UKB), Germany.

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http://dx.doi.org/10.1016/j.leukres.2017.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115818PMC
August 2017

Expression of CD25 on leukemic stem cells in BCR-ABL1 CML: Potential diagnostic value and functional implications.

Exp Hematol 2017 07 27;51:17-24. Epub 2017 Apr 27.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X173013
Publisher Site
http://dx.doi.org/10.1016/j.exphem.2017.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044418PMC
July 2017