Peter Sarkies

Peter Sarkies

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Peter Sarkies

Peter Sarkies

Publications by authors named "Peter Sarkies"

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Molecular mechanisms of epigenetic inheritance: Possible evolutionary implications.

Authors:
Peter Sarkies

Semin Cell Dev Biol 2020 Jan 21;97:106-115. Epub 2019 Jun 21.

MRC London Institute of Medical Sciences, Du Cane Road, London, W120NN, United Kingdom; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W120NN, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2019.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945114PMC
January 2020

Mechanistic Insights into Cytosine-N3 Methylation by DNA Methyltransferase DNMT3A.

J Mol Biol 2019 Aug 21;431(17):3139-3145. Epub 2019 Jun 21.

Department of Biochemistry, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Allmandring 31, 70569 Stuttgart, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.06.015DOI Listing
August 2019

The piRNA pathway responds to environmental signals to establish intergenerational adaptation to stress.

BMC Biol 2018 09 18;16(1):103. Epub 2018 Sep 18.

MRC London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.

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https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-01
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http://dx.doi.org/10.1186/s12915-018-0571-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145337PMC
September 2018

An Alternative STAT Signaling Pathway Acts in Viral Immunity in .

mBio 2017 09 5;8(5). Epub 2017 Sep 5.

Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom

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http://dx.doi.org/10.1128/mBio.00924-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587905PMC
September 2017

Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression.

Genome Res 2016 09 18;26(9):1219-32. Epub 2016 May 18.

Department of Biology, Hong Kong Baptist University, Hong Kong, China; State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Hong Kong, China.

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http://dx.doi.org/10.1101/gr.204479.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052035PMC
September 2016

Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans.

J Virol 2015 Dec 23;89(23):12035-46. Epub 2015 Sep 23.

Wellcome Trust Cancer Research United Kingdom Gurdon Institute, University of Cambridge, Cambridge, United Kingdom Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom Department of Genetics, University of Cambridge, Cambridge, United Kingdom

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http://dx.doi.org/10.1128/JVI.03664-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645334PMC
December 2015

E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans.

Sci Rep 2015 Apr 15;5:9597. Epub 2015 Apr 15.

Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Rd, Cambridge CB2 1QN, UK.

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http://dx.doi.org/10.1038/srep09597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397834PMC
April 2015

Tertiary siRNAs mediate paramutation in C. elegans.

PLoS Genet 2015 Mar 26;11(3):e1005078. Epub 2015 Mar 26.

Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom; Department of Biochemistry and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1005078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374809PMC
March 2015

Histone H3.3 is required to maintain replication fork progression after UV damage.

Curr Biol 2014 Sep 4;24(18):2195-2201. Epub 2014 Sep 4.

Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2014.07.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175177PMC
September 2014

Small RNAs break out: the molecular cell biology of mobile small RNAs.

Nat Rev Mol Cell Biol 2014 Aug;15(8):525-35

Gurdon Institute and Department of Genetics, University of Cambridge, The Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Road, Cambridge CB2 1QN, UK.

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http://dx.doi.org/10.1038/nrm3840DOI Listing
August 2014

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice.

Nat Neurosci 2014 May 13;17(5):667-9. Epub 2014 Apr 13.

Brain Research Institute, Neuroscience Center Zürich, University of Zürich and Swiss Federal Institute of Technology, Zürich, Switzerland.

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http://dx.doi.org/10.1038/nn.3695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333222PMC
May 2014

Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants.

Cell Rep 2014 May 24;7(3):762-73. Epub 2014 Apr 24.

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247140025
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http://dx.doi.org/10.1016/j.celrep.2014.03.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049074PMC
May 2014

PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans.

Genes Dev 2014 Apr;28(7):783-96

Wellcome Trust Cancer Research UK Gurdon Institute, Department of Genetics, University of Cambridge, Cambridge CB2 1QN, United Kingdom;

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http://dx.doi.org/10.1101/gad.238105.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015492PMC
April 2014

A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity.

Elife 2013 Oct 8;2:e00994. Epub 2013 Oct 8.

Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge , Cambridge , United Kingdom ; Department of Biochemistry , University of Cambridge , Cambridge , United Kingdom.

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https://elifesciences.org/content/2/e00994-download.pdf
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http://elifesciences.org/lookup/doi/10.7554/eLife.00994
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http://dx.doi.org/10.7554/eLife.00994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793227PMC
October 2013

Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans.

Genome Res 2013 Aug 28;23(8):1258-70. Epub 2013 Jun 28.

Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom.

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http://dx.doi.org/10.1101/gr.153296.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730100PMC
August 2013

RNAi pathways in the recognition of foreign RNA: antiviral responses and host-parasite interactions in nematodes.

Biochem Soc Trans 2013 Aug;41(4):876-80

The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 0QN, UK.

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http://dx.doi.org/10.1042/BST20130021DOI Listing
August 2013

Molecular biology. Is there social RNA?

Science 2013 Aug;341(6145):467-8

Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1126/science.1243175DOI Listing
August 2013

Propagation of histone marks and epigenetic memory during normal and interrupted DNA replication.

Cell Mol Life Sci 2012 Mar 2;69(5):697-716. Epub 2011 Oct 2.

Division of Protein and Nucleic Acid Chemistry, Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1007/s00018-011-0824-1DOI Listing
March 2012

Cellular epigenetic stability and cancer.

Trends Genet 2012 Mar 5;28(3):118-27. Epub 2012 Jan 5.

Medical Research Council Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Hills Road, Cambridge, CB2 0QH, UK.

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http://dx.doi.org/10.1016/j.tig.2011.11.005DOI Listing
March 2012

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

Nucleic Acids Res 2012 Feb 22;40(4):1485-98. Epub 2011 Oct 22.

Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1093/nar/gkr868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287192PMC
February 2012

Epigenetic instability due to defective replication of structured DNA.

Mol Cell 2010 Dec;40(5):703-13

Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1016/j.molcel.2010.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145961PMC
December 2010

Motogenic sites in human fibronectin are masked by long range interactions.

J Biol Chem 2009 Jun 14;284(23):15668-75. Epub 2009 Apr 14.

Department of Biochemistry, University of Oxford, Oxford OX1 3QU , UK.

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http://dx.doi.org/10.1074/jbc.M109.003673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708863PMC
June 2009

Genetic selection of activatory mutations in KcsA.

Channels (Austin) 2008 Nov-Dec;2(6):413-8. Epub 2008 Nov 27.

Oxford Centre for Gene Function, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688072PMC
http://dx.doi.org/10.4161/chan.2.6.6874DOI Listing
April 2009