Peter S Braund

Peter S Braund

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Peter S Braund

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Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.

Circulation 2020 Jul 13. Epub 2020 Jul 13.

Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, London, UK; Bart's Heart Centre, St Bartholomew's Hospital, London, EC1A2DA, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.045526DOI Listing
July 2020

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.

Authors:
Evangelos Evangelou He Gao Congying Chu Georgios Ntritsos Paul Blakeley Andrew R Butts Raha Pazoki Hideaki Suzuki Fotios Koskeridis Andrianos M Yiorkas Ibrahim Karaman Joshua Elliott Qiang Luo Stefanie Aeschbacher Traci M Bartz Sebastian E Baumeister Peter S Braund Michael R Brown Jennifer A Brody Toni-Kim Clarke Niki Dimou Jessica D Faul Georg Homuth Anne U Jackson Katherine A Kentistou Peter K Joshi Rozenn N Lemaitre Penelope A Lind Leo-Pekka Lyytikäinen Massimo Mangino Yuri Milaneschi Christopher P Nelson Ilja M Nolte Mia-Maria Perälä Ozren Polasek David Porteous Scott M Ratliff Jennifer A Smith Alena Stančáková Alexander Teumer Samuli Tuominen Sébastien Thériault Jagadish Vangipurapu John B Whitfield Alexis Wood Jie Yao Bing Yu Wei Zhao Dan E Arking Juha Auvinen Chunyu Liu Minna Männikkö Lorenz Risch Jerome I Rotter Harold Snieder Juha Veijola Alexandra I Blakemore Michael Boehnke Harry Campbell David Conen Johan G Eriksson Hans J Grabe Xiuqing Guo Pim van der Harst Catharina A Hartman Caroline Hayward Andrew C Heath Marjo-Riitta Jarvelin Mika Kähönen Sharon L R Kardia Michael Kühne Johanna Kuusisto Markku Laakso Jari Lahti Terho Lehtimäki Andrew M McIntosh Karen L Mohlke Alanna C Morrison Nicholas G Martin Albertine J Oldehinkel Brenda W J H Penninx Bruce M Psaty Olli T Raitakari Igor Rudan Nilesh J Samani Laura J Scott Tim D Spector Niek Verweij David R Weir James F Wilson Daniel Levy Ioanna Tzoulaki Jimmy D Bell Paul M Matthews Adrian Rothenfluh Sylvane Desrivières Gunter Schumann Paul Elliott

Nat Hum Behav 2019 09 29;3(9):950-961. Epub 2019 Jul 29.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41562-019-0653-zDOI Listing
September 2019

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals.

Authors:
Raymond Noordam William J Young Reem Salman Jørgen K Kanters Marten E van den Berg Diana van Heemst Henry J Lin Sandhi Maria Barreto Mary L Biggs Ginevra Biino Eulalia Catamo Maria Pina Concas Jun Ding Daniel S Evans Luisa Foco Niels Grarup Leo-Pekka Lyytikäinen Massimo Mangino Hao Mei Peter J van der Most Martina Müller-Nurasyid Christopher P Nelson Yong Qian Linda Repetto M Abdullah Said Nabi Shah Katharina Schramm Pedro G Vidigal Stefan Weiss Jie Yao Nuno R Zilhao Jennifer A Brody Peter S Braund Marco Brumat Eric Campana Paraskevi Christofidou Mark J Caulfield Alessandro De Grandi Anna F Dominiczak Alex S F Doney Gudny Eiriksdottir Christina Ellervik Luana Giatti Martin Gögele Claus Graff Xiuqing Guo Pim van der Harst Peter K Joshi Mika Kähönen Bryan Kestenbaum Maria F Lima-Costa Allan Linneberg Arie C Maan Thomas Meitinger Sandosh Padmanabhan Cristian Pattaro Annette Peters Astrid Petersmann Peter Sever Mortiz F Sinner Xia Shen Alice Stanton Konstantin Strauch Elsayed Z Soliman Kirill V Tarasov Kent D Taylor Chris H L Thio André G Uitterlinden Simona Vaccargiu Melanie Waldenberger Antonietta Robino Adolfo Correa Francesco Cucca Steven R Cummings Marcus Dörr Giorgia Girotto Vilmundur Gudnason Torben Hansen Susan R Heckbert Christian R Juhl Stefan Kääb Terho Lehtimäki Yongmei Liu Paulo A Lotufo Colin N A Palmer Mario Pirastu Peter P Pramstaller Antonio Luiz P Ribeiro Jerome I Rotter Nilesh J Samani Harold Snieder Tim D Spector Bruno H Stricker Niek Verweij James F Wilson James G Wilson J Wouter Jukema Andrew Tinker Christopher H Newton-Cheh Nona Sotoodehnia Dennis O Mook-Kanamori Patricia B Munroe Helen R Warren

J Am Coll Cardiol 2019 06;73(24):3118-3131

Clinical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2019.03.519DOI Listing
June 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Authors:
Yun Ju Sung Lisa de Las Fuentes Thomas W Winkler Daniel I Chasman Amy R Bentley Aldi T Kraja Ioanna Ntalla Helen R Warren Xiuqing Guo Karen Schwander Alisa K Manning Michael R Brown Hugues Aschard Mary F Feitosa Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Tuomas O Kilpeläinen Melissa A Richard Stella Aslibekyan Traci M Bartz Rajkumar Dorajoo Changwei Li Yongmei Liu Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Candace M Kammerer Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Colin A McKenzie Christopher P Nelson Raymond Noordam Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Robert J Waken Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan E Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Brian Cade Archie Campbell Mickaël Canouil Aravinda Chakravarti Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante C Charles Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Albert Hofman Barbara V Howard Steven C Hunt Marguerite R Irvin Yucheng Jia Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Charles B Kooperberg Jose E Krieger Michiaki Kubo Zoltan Kutalik Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Joseph H Lee Benjamin Lehne Daniel Levy Cora E Lewis Yize Li Sing Hui Lim Ching-Ti Liu Jianjun Liu Jingmin Liu Yeheng Liu Marie Loh Kurt K Lohman Tin Louie Reedik Mägi Koichi Matsuda Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Thomas H Mosley Mike A Nalls Ubaydah Nasri Jeff R O'Connell Adesola Ogunniyi Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David Porteous Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Mario Sims Colleen M Sitlani Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Gregory Wilson Mary K Wojczynski Yong-Bing Xiang Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen David R Weir Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost Bruno Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Albertine J Oldehinkel Alexandre C Pereira Thomas Perls Rainer Rauramaa Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins Ananda R Wickremasinghe Tangchun Wu Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason James Hixson Sharon L R Kardia Stephen B Kritchevsky Bruce M Psaty Rob M van Dam Donna K Arnett Dennis O Mook-Kanamori Myriam Fornage Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Charles N Rotimi Laura J Bierut Xiaofeng Zhu L Adrienne Cupples Michael A Province Jerome I Rotter Paul W Franks Kenneth Rice Paul Elliott Mark J Caulfield W James Gauderman Patricia B Munroe Dabeeru C Rao Alanna C Morrison

Hum Mol Genet 2019 Apr 10. Epub 2019 Apr 10.

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.

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https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg
Publisher Site
http://dx.doi.org/10.1093/hmg/ddz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644157PMC
April 2019

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 12;50(12):1755

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://www.nature.com/articles/s41588-018-0297-3
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http://dx.doi.org/10.1038/s41588-018-0297-3DOI Listing
December 2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

Authors:
Evangelos Evangelou Helen R Warren David Mosen-Ansorena Borbala Mifsud Raha Pazoki He Gao Georgios Ntritsos Niki Dimou Claudia P Cabrera Ibrahim Karaman Fu Liang Ng Marina Evangelou Katarzyna Witkowska Evan Tzanis Jacklyn N Hellwege Ayush Giri Digna R Velez Edwards Yan V Sun Kelly Cho J Michael Gaziano Peter W F Wilson Philip S Tsao Csaba P Kovesdy Tonu Esko Reedik Mägi Lili Milani Peter Almgren Thibaud Boutin Stéphanie Debette Jun Ding Franco Giulianini Elizabeth G Holliday Anne U Jackson Ruifang Li-Gao Wei-Yu Lin Jian'an Luan Massimo Mangino Christopher Oldmeadow Bram Peter Prins Yong Qian Muralidharan Sargurupremraj Nabi Shah Praveen Surendran Sébastien Thériault Niek Verweij Sara M Willems Jing-Hua Zhao Philippe Amouyel John Connell Renée de Mutsert Alex S F Doney Martin Farrall Cristina Menni Andrew D Morris Raymond Noordam Guillaume Paré Neil R Poulter Denis C Shields Alice Stanton Simon Thom Gonçalo Abecasis Najaf Amin Dan E Arking Kristin L Ayers Caterina M Barbieri Chiara Batini Joshua C Bis Tineka Blake Murielle Bochud Michael Boehnke Eric Boerwinkle Dorret I Boomsma Erwin P Bottinger Peter S Braund Marco Brumat Archie Campbell Harry Campbell Aravinda Chakravarti John C Chambers Ganesh Chauhan Marina Ciullo Massimiliano Cocca Francis Collins Heather J Cordell Gail Davies Martin H de Borst Eco J de Geus Ian J Deary Joris Deelen Fabiola Del Greco M Cumhur Yusuf Demirkale Marcus Dörr Georg B Ehret Roberto Elosua Stefan Enroth A Mesut Erzurumluoglu Teresa Ferreira Mattias Frånberg Oscar H Franco Ilaria Gandin Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Anuj Goel Alan J Gow Vilmundur Gudnason Xiuqing Guo Ulf Gyllensten Anders Hamsten Tamara B Harris Sarah E Harris Catharina A Hartman Aki S Havulinna Andrew A Hicks Edith Hofer Albert Hofman Jouke-Jan Hottenga Jennifer E Huffman Shih-Jen Hwang Erik Ingelsson Alan James Rick Jansen Marjo-Riitta Jarvelin Roby Joehanes Åsa Johansson Andrew D Johnson Peter K Joshi Pekka Jousilahti J Wouter Jukema Antti Jula Mika Kähönen Sekar Kathiresan Bernard D Keavney Kay-Tee Khaw Paul Knekt Joanne Knight Ivana Kolcic Jaspal S Kooner Seppo Koskinen Kati Kristiansson Zoltan Kutalik Maris Laan Marty Larson Lenore J Launer Benjamin Lehne Terho Lehtimäki David C M Liewald Li Lin Lars Lind Cecilia M Lindgren YongMei Liu Ruth J F Loos Lorna M Lopez Yingchang Lu Leo-Pekka Lyytikäinen Anubha Mahajan Chrysovalanto Mamasoula Jaume Marrugat Jonathan Marten Yuri Milaneschi Anna Morgan Andrew P Morris Alanna C Morrison Peter J Munson Mike A Nalls Priyanka Nandakumar Christopher P Nelson Teemu Niiranen Ilja M Nolte Teresa Nutile Albertine J Oldehinkel Ben A Oostra Paul F O'Reilly Elin Org Sandosh Padmanabhan Walter Palmas Aarno Palotie Alison Pattie Brenda W J H Penninx Markus Perola Annette Peters Ozren Polasek Peter P Pramstaller Quang Tri Nguyen Olli T Raitakari Meixia Ren Rainer Rettig Kenneth Rice Paul M Ridker Janina S Ried Harriëtte Riese Samuli Ripatti Antonietta Robino Lynda M Rose Jerome I Rotter Igor Rudan Daniela Ruggiero Yasaman Saba Cinzia F Sala Veikko Salomaa Nilesh J Samani Antti-Pekka Sarin Reinhold Schmidt Helena Schmidt Nick Shrine David Siscovick Albert V Smith Harold Snieder Siim Sõber Rossella Sorice John M Starr David J Stott David P Strachan Rona J Strawbridge Johan Sundström Morris A Swertz Kent D Taylor Alexander Teumer Martin D Tobin Maciej Tomaszewski Daniela Toniolo Michela Traglia Stella Trompet Jaakko Tuomilehto Christophe Tzourio André G Uitterlinden Ahmad Vaez Peter J van der Most Cornelia M van Duijn Anne-Claire Vergnaud Germaine C Verwoert Veronique Vitart Uwe Völker Peter Vollenweider Dragana Vuckovic Hugh Watkins Sarah H Wild Gonneke Willemsen James F Wilson Alan F Wright Jie Yao Tatijana Zemunik Weihua Zhang John R Attia Adam S Butterworth Daniel I Chasman David Conen Francesco Cucca John Danesh Caroline Hayward Joanna M M Howson Markku Laakso Edward G Lakatta Claudia Langenberg Olle Melander Dennis O Mook-Kanamori Colin N A Palmer Lorenz Risch Robert A Scott Rodney J Scott Peter Sever Tim D Spector Pim van der Harst Nicholas J Wareham Eleftheria Zeggini Daniel Levy Patricia B Munroe Christopher Newton-Cheh Morris J Brown Andres Metspalu Adriana M Hung Christopher J O'Donnell Todd L Edwards Bruce M Psaty Ioanna Tzoulaki Michael R Barnes Louise V Wain Paul Elliott Mark J Caulfield

Nat Genet 2018 10 17;50(10):1412-1425. Epub 2018 Sep 17.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0205-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284793PMC
October 2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Authors:
Yun J Sung Thomas W Winkler Lisa de Las Fuentes Amy R Bentley Michael R Brown Aldi T Kraja Karen Schwander Ioanna Ntalla Xiuqing Guo Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Mary F Feitosa Tuomas O Kilpeläinen Melissa A Richard Raymond Noordam Stella Aslibekyan Hugues Aschard Traci M Bartz Rajkumar Dorajoo Yongmei Liu Alisa K Manning Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Helen R Warren Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando Pires Hartwig Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian 'an Luan Colin A McKenzie He Meian Christopher P Nelson Rainer Rauramaa Nicole Schupf Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Claudia P Cabrera Brian Cade Yu Caizheng Archie Campbell Mickaël Canouil Aravinda Chakravarti Ganesh Chauhan Kaare Christensen Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Stephanie Debette Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Virginia A Fisher Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante Misa Graff C Charles Gu Dongfeng Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Albert Hofman Barbara V Howard Steven Hunt Marguerite R Irvin Yucheng Jia Roby Joehanes Anne E Justice Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Pirjo Komulainen Charles Kooperberg Jose E Krieger Michiaki Kubo Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Sing Hui Lim Shiow Lin Ching-Ti Liu Jianjun Liu Jingmin Liu Kiang Liu Yeheng Liu Marie Loh Kurt K Lohman Jirong Long Tin Louie Reedik Mägi Anubha Mahajan Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Andrew P Morris Thomas H Mosley Peter Munson Alison D Murray Mike A Nalls Ubaydah Nasri Jill M Norris Kari North Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Sudha Seshadri Peter Sever Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya X Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost B Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Anne B Newman Albertine J Oldehinkel Alexandre C Pereira Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason Sharon L R Kardia Stephen B Kritchevsky Daniel Levy Jeff R O'Connell Bruce M Psaty Rob M van Dam Mario Sims Donna K Arnett Dennis O Mook-Kanamori Tanika N Kelly Ervin R Fox Caroline Hayward Myriam Fornage Charles N Rotimi Michael A Province Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Mark J Caulfield Paul Elliott Kenneth Rice Patricia B Munroe Alanna C Morrison L Adrienne Cupples Dabeeru C Rao Daniel I Chasman

Am J Hum Genet 2018 03 15;102(3):375-400. Epub 2018 Feb 15.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985266PMC
March 2018

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Authors:
Louise V Wain Ahmad Vaez Rick Jansen Roby Joehanes Peter J van der Most A Mesut Erzurumluoglu Paul F O'Reilly Claudia P Cabrera Helen R Warren Lynda M Rose Germaine C Verwoert Jouke-Jan Hottenga Rona J Strawbridge Tonu Esko Dan E Arking Shih-Jen Hwang Xiuqing Guo Zoltan Kutalik Stella Trompet Nick Shrine Alexander Teumer Janina S Ried Joshua C Bis Albert V Smith Najaf Amin Ilja M Nolte Leo-Pekka Lyytikäinen Anubha Mahajan Nicholas J Wareham Edith Hofer Peter K Joshi Kati Kristiansson Michela Traglia Aki S Havulinna Anuj Goel Mike A Nalls Siim Sõber Dragana Vuckovic Jian'an Luan Fabiola Del Greco M Kristin L Ayers Jaume Marrugat Daniela Ruggiero Lorna M Lopez Teemu Niiranen Stefan Enroth Anne U Jackson Christopher P Nelson Jennifer E Huffman Weihua Zhang Jonathan Marten Ilaria Gandin Sarah E Harris Tatijana Zemunik Yingchang Lu Evangelos Evangelou Nabi Shah Martin H de Borst Massimo Mangino Bram P Prins Archie Campbell Ruifang Li-Gao Ganesh Chauhan Christopher Oldmeadow Gonçalo Abecasis Maryam Abedi Caterina M Barbieri Michael R Barnes Chiara Batini John Beilby Tineka Blake Michael Boehnke Erwin P Bottinger Peter S Braund Morris Brown Marco Brumat Harry Campbell John C Chambers Massimiliano Cocca Francis Collins John Connell Heather J Cordell Jeffrey J Damman Gail Davies Eco J de Geus Renée de Mutsert Joris Deelen Yusuf Demirkale Alex S F Doney Marcus Dörr Martin Farrall Teresa Ferreira Mattias Frånberg He Gao Vilmantas Giedraitis Christian Gieger Franco Giulianini Alan J Gow Anders Hamsten Tamara B Harris Albert Hofman Elizabeth G Holliday Jennie Hui Marjo-Riitta Jarvelin Åsa Johansson Andrew D Johnson Pekka Jousilahti Antti Jula Mika Kähönen Sekar Kathiresan Kay-Tee Khaw Ivana Kolcic Seppo Koskinen Claudia Langenberg Marty Larson Lenore J Launer Benjamin Lehne David C M Liewald Li Lin Lars Lind François Mach Chrysovalanto Mamasoula Cristina Menni Borbala Mifsud Yuri Milaneschi Anna Morgan Andrew D Morris Alanna C Morrison Peter J Munson Priyanka Nandakumar Quang Tri Nguyen Teresa Nutile Albertine J Oldehinkel Ben A Oostra Elin Org Sandosh Padmanabhan Aarno Palotie Guillaume Paré Alison Pattie Brenda W J H Penninx Neil Poulter Peter P Pramstaller Olli T Raitakari Meixia Ren Kenneth Rice Paul M Ridker Harriëtte Riese Samuli Ripatti Antonietta Robino Jerome I Rotter Igor Rudan Yasaman Saba Aude Saint Pierre Cinzia F Sala Antti-Pekka Sarin Reinhold Schmidt Rodney Scott Marc A Seelen Denis C Shields David Siscovick Rossella Sorice Alice Stanton David J Stott Johan Sundström Morris Swertz Kent D Taylor Simon Thom Ioanna Tzoulaki Christophe Tzourio André G Uitterlinden Uwe Völker Peter Vollenweider Sarah Wild Gonneke Willemsen Alan F Wright Jie Yao Sébastien Thériault David Conen John Attia Peter Sever Stéphanie Debette Dennis O Mook-Kanamori Eleftheria Zeggini Tim D Spector Pim van der Harst Colin N A Palmer Anne-Claire Vergnaud Ruth J F Loos Ozren Polasek John M Starr Giorgia Girotto Caroline Hayward Jaspal S Kooner Cecila M Lindgren Veronique Vitart Nilesh J Samani Jaakko Tuomilehto Ulf Gyllensten Paul Knekt Ian J Deary Marina Ciullo Roberto Elosua Bernard D Keavney Andrew A Hicks Robert A Scott Paolo Gasparini Maris Laan YongMei Liu Hugh Watkins Catharina A Hartman Veikko Salomaa Daniela Toniolo Markus Perola James F Wilson Helena Schmidt Jing Hua Zhao Terho Lehtimäki Cornelia M van Duijn Vilmundur Gudnason Bruce M Psaty Annette Peters Rainer Rettig Alan James J Wouter Jukema David P Strachan Walter Palmas Andres Metspalu Erik Ingelsson Dorret I Boomsma Oscar H Franco Murielle Bochud Christopher Newton-Cheh Patricia B Munroe Paul Elliott Daniel I Chasman Aravinda Chakravarti Joanne Knight Andrew P Morris Daniel Levy Martin D Tobin Harold Snieder Mark J Caulfield Georg B Ehret

Hypertension 2017 Jul 24. Epub 2017 Jul 24.

From the Department of Health Sciences (L.V.W., A.M.E., N. Shrine, C.B., T.B., M.D.T.), and Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre (C.P.N., P.S.B., N.J.S.), University of Leicester, United Kingdom; Department of Epidemiology (A.V., P.J.v.d.M., I.M.N., H. Snieder), Division of Nephrology, Department of Internal Medicine (M.H.d.B., M.A.S.), Interdisciplinary Center Psychopathology and Emotion Regulation (IPCE) (A.J.O., H.R., C.A.H.), Department of Genetics, (M.S.), and Department of Cardiology (P.v.d.H.), University of Groningen, University Medical Center Groningen, The Netherlands; Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Iran (A.V.); Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, The Netherlands (R. Jansen); Hebrew SeniorLife, Harvard Medical School, Boston, MA (R. Joehanes); National Heart, Lung and Blood Institute's Framingham Heart Study, MA (R. Joehanes, A.D.J., M. Larson); Institute of Psychiatry, Psychology and Neuroscience (P.F.O.), and Department of Twin Research and Genetic Epidemiology (M.M., C. Menni, T.D.S.), King's College London, United Kingdom; Clinical Pharmacology, William Harvey Research Institute (C.P.C., H.R.W., M.R.B., M. Brown, B.M., M.R., P.B.M., M.J.C.) and NIHR Barts Cardiovascular Biomedical Research Unit (C.P.C., H.R.W., M.R.B., M. Brown, P.B.M., M.J.C.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA (L.M.R., F.G., P.M.R., D.I.C.); Department of Epidemiology (G.C.V., A. Hofman, A.G.U., O.H.F.), Genetic Epidemiology Unit, Department of Epidemiology (N.A., B.A.O., C.M.v.D.), and Department of Internal Medicine (A.G.U.), Erasmus MC, Rotterdam, The Netherlands; Department of Biological Psychology, Vrije Universiteit, Amsterdam, EMGO+ Institute, VU University Medical Center, The Netherlands (J.-J.H., E.J.d.G., G.W., D.I.B.); Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden (R.J.S., M. Frånberg, A. Hamsten); Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden (R.J.S., M. Frånberg, A. Hamsten); Estonian Genome Center (T.E., E.O., A. Metspalu), Institute of Biomedicine and Translational Medicine (S.S., M. Laan), and Estonian Genome Center (M.P.), University of Tartu, Estonia; Divisions of Endocrinology/Children's Hospital, Boston, MA (T.E.); Broad Institute of Harvard and MIT, Cambridge, MA (T.E., C.M.L., C.N.-C.); Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (D.E.A., P.N., A. Chakravarti, G.B.E.); The Population Science Branch, Division of Intramural Research, National Heart Lung and Blood Institute (S.-J.H., D.L.), Laboratory of Neurogenetics, National Institute on Aging (M.A.N.), Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute (F.C.), and Center for Information Technology (Y.D., P.J.M., Q.T.N.), National Institutes of Health, Bethesda, MD; The Framingham Heart Study, Framingham, MA (S.-J.H., D.L.); The Institute for Translational Genomics and Population Sciences, Department of Pediatrics (X.G., J.Y.), and The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine (J.I.R.), LABioMed at Harbor-UCLA Medical Center, Torrance, CA; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland (Z.K., M. Bochud); Swiss Institute of Bioinformatics, Lausanne, Switzerland (Z.K.); Department of Cardiology (S. Trompet, J.W.J.) Department of Gerontology and Geriatrics (S. Trompet), Department of Clinical Epidemiology (R.L.-G., R.d.M., D.O.M.-K.), Department of Molecular Epidemiology (J.D.), and Department of Public Health and Primary Care (D.O.M.-K.), Leiden University Medical Center, The Netherlands; Institute for Community Medicine (A.T.), Department of Internal Medicine B (M.D.), and Interfaculty Institute for Genetics and Functional Genomics (U.V.), University Medicine Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Germany (A.T., M.D., U.V.); Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg, Germany (J.S.R., A. Peters); Cardiovascular Health Research Unit, Department of Medicine (J.C.B., B.M.P.) and Departments of Biostatistics (K.R.), Epidemiology (B.M.P.), and Health Services (B.M.P.), University of Washington, Seattle; Icelandic Heart Association, Kopavogur, Iceland (A.V.S., V. Gudnason); Faculty of Medicine, University of Iceland, Reykjavik, Iceland (A.V.S., V. Gudnason); Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., T.L.); Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Finland (L.-P.L., T.L.); Wellcome Trust Centre for Human Genetics (A. Mahajan, A.G., M. Farrall, T.F., C.M.L., H.W., A.P.M.), and Division of Cardiovascular Medicine, Radcliffe Department of Medicine (A.G., M. Farrall, H.W.), University of Oxford, United Kingdom; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, United Kingdom (N.J.W., J.L., C.L., R.J.F.L., R.A.S., J.H.Z.); Clinical Division of Neurogeriatrics, Department of Neurology (E.H., R. Schmidt), Institute of Medical Informatics, Statistics and Documentation (E.H.), and Department of Neurology (H. Schmidt), Medical University Graz, Austria; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics (P.K.J., H.C., I.R., S.W., J.F.W.), Centre for Cognitive Ageing and Cognitive Epidemiology (L.M.L., S.E.H., G.D., A.J.G., D.C.M.L., J.M.S., I.J.D.), Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine (A. Campbell), Generation Scotland, Centre for Genomic and Experimental Medicine (A. Campbell, S.P., C.H.), Department of Psychology (G.D., D.C.M.L., A. Pattie, I.J.D.), Alzheimer Scotland Dementia Research Centre (J.M.S.), and Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (C.H.), University of Edinburgh, Scotland, United Kingdom; Department of Health (K.K., A.S.H., T. Niiranen, P.J., A.J., S. Koskinen, P.K., V.S., M.P.), and Chronic Disease Prevention Unit (J.T.), National Institute for Health and Welfare (THL), Helsinki, Finland; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy (M.T., C.M.B., C.F.S., D.T.); Data Tecnica International, Glen Echo, MD (M.A.N.); Medical Genetics, IRCCS-Burlo Garofolo Children Hospital, Trieste, Italy (D.V., G.G., P.G.); Department of Medical, Surgical and Health Sciences, University of Trieste, Italy (D.V., I.G., M. Brumat, M. Cocca, A. Morgan, G.G., P.G.); Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, Italy (F.D.G.M., P.P.P., A.S.P., A.A.H.); Department of Genetics and Genomic Sciences (K.L.A.), The Charles Bronfman Institute for Personalized Medicine (Y.L., E.P.B., R.J.F.L.), and Mindich Child health Development Institute (R.J.F.L.), Icahn School of Medicine at Mount Sinai, New York; Cardiovascular Epidemiology and Genetics, IMIM, and CIBERCV, Barcelona, Spain (J. Marrugat, R.E.); Institute of Genetics and Biophysics A. Buzzati-Traverso, CNR, Napoli, Italy (D.R., T. Nutile, R. Sorice, M. Ciullo); Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin (L.M.L.); UCD Conway Institute, Centre for Proteome Research (L.M.L.), and School of Medicine, Conway Institute (D.C.S.), University College Dublin, Belfield, Ireland; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Sweden (S.E., Å. Johansson, U.G.); Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor (A.U.J., M. Boehnke); NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester United Kingdom (C.P.N., P.S.B., N.J.S.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.E.H., V.V., J. Marten, A.F.W., J.F.W.), and Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine (S.E.H.), University of Edinburgh, Western General Hospital, Scotland, United Kingdom; Department of Epidemiology and Biostatistics, School of Public Health (W.Z., E.E., J.C.C., H.G., B.L., I.T., A.-C.V.), MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health (M.-R.J., P.E.), School of Public Health (N.P.), International Centre for Circulatory Health (S. Thom), and National Heart and Lung Institute (P.S.), Imperial College London, United Kingdom; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Southall, United Kingdom (W.Z., J.C.C., J.S.K.); Department of Medical Biology, Faculty of Medicine, University of Split, Croatia (T.Z.); Department of Hygiene and Epidemiology, University of Ioannina Medical School, Greece (E.E.); Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Scotland, United Kingdom (N. Shah, A.S.F.D., C.N.A.P.); Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan (N. Shah); National Institute for Health Research Biomedical Research Centre, London, United Kingdom (M.M.); Department of Human Genetics, Wellcome Trust Sanger Institute, United Kingdom (B.P.P., E.Z.); INSERM U 1219, Bordeaux Population Health Center, France (G.C., C.T., S.D.); Bordeaux University, France (G.C., C.T., S.D.); Hunter Medical Research Institute, New Lambton, NSW, Australia (C.O., E.G.H., R. Scott, J.A.); Center for Statistical Genetics, Department of Biostatistics, Ann Arbor, MI (G.A.); Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Iran (M.A.); Busselton Population Medical Research Institute, Western Australia (J.B., J.H.); PathWest Laboratory Medicine of Western Australia, Nedlands (J.B., J.H.); School of Pathology and Laboratory Medicine (J.B., J.H.), School of Population and Global Health (J.H.), and School of Medicine and Pharmacology (A. James), The University of Western Australia, Nedlands; Imperial College Healthcare NHS Trust, London, United Kingdom (J.C.C., J.S.K.); University of Dundee, Ninewells Hospital & Medical School, United Kingdom (J.C.); Institute of Genetic Medicine (H.J.C.), and Institute of Health and Society (C. Mamasoula), Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Pathology, Amsterdam Medical Center, The Netherlands (J.J.D.); Department of Numerical Analysis and Computer Science, Stockholm University, Sweden (M. Frånberg); Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden (V. Giedraitis); Helmholtz Zentrum Muenchen, Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH), Neuherberg, Germany (C.G.); Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, United Kingdom (A.J.G.); Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging (T.B.H., L.J.L.); Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (A. Hofman); Center For Life-Course Health Research (M.-R.J.), and Biocenter Oulu (M.-R.J.), University of Oulu, Finland; Unit of Primary Care, Oulu University Hospital, Finland (M.-R.J.); National Heart, Lung and Blood Institute, Cardiovascular Epidemiology and Human Genomics Branch, Bethesda, MD (A.D.J.); Department of Clinical Physiology, Tampere University Hospital, Finland (M.K.); Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Finland (M.K.); Cardiovascular Research Center (S. Kathiresan, C.N.-C.); Center for Human Genetics (S. Kathiresan), and Center for Human Genetic Research (C.N.-C.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (S. Kathiresan, C.N.-C.); Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, United Kingdom (K.-T.K.); Department of Public Health, Faculty of Medicine, University of Split, Croatia (I.K., O.P.); Cardiology, Department of Specialties of Medicine, Geneva University Hospital, Switzerland (L. Lin, F.M., G.B.E.); Department of Medical Sciences, Cardiovascular Epidemiology (L. Lind, J.S.), and Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory (E.I.), Uppsala University, Sweden; Department of Psychiatry, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands (Y.M., B.W.J.H.P.); School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, Scotland, United Kingdom (A.D.M.); Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston (A.C.M.); British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences (S.P.), and Institute of Cardiovascular and Medical Sciences, Faculty of Medicine (D.J.S.), University of Glasgow, United Kingdom; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland (A. Palotie, S.R., A.-P.S., M.P.); Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada (G.P., S. Thériault); Department of Neurology, General Central Hospital, Bolzano, Italy (P.P.P.); Department of Neurology, University of Lübeck, Germany (P.P.P.); Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland (O.T.R.); Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland (O.T.R.); Department of Cardiology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China (M.R.); Harvard Medical School, Boston, MA (P.M.R., D.I.C.); Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy (A.R.); Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Austria (Y.S., H. Schmidt); INSERM U1078, Etablissement Français du Sang, Brest Cedex, France (A.S.P.); Faculty of Health, University of Newcastle, Callaghan, NSW, Australia (R. Scott, J.A.); John Hunter Hospital, New Lambton, NSW, Australia (R. Scott, J.A.); The New York Academy of Medicine, New York (D.S.); IRCCS Neuromed, Pozzilli, Isernia, Italy (R. Sorice, M. Ciullo); Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin 2, Ireland (A.S.); Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (K.D.T.); Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA (K.D.T.); Department of Public Health (C.T.), and Department of Neurology (S.D.), Bordeaux University Hospital, France; Department of Internal Medicine, Lausanne University Hospital, CHUV, Switzerland (P.V.); Population Health Research Institute, McMaster University, Hamilton Ontario, Canada (D.C.); National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, United Kingdom (J.S.K.); Dasman Diabetes Institute, Kuwait (J.T.); Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia (J.T.); Department of Neurosciences and Preventive Medicine, Danube-University Krems, Austria (J.T.); Division of Cardiovascular Sciences, The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust, United Kingdom (B.D.K.); Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem (Y.M.L.); Kaiser Permanent Washington Health Research Institute, Seattle, WA (B.M.P.); Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany (R.R); Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Nedlands, Western Australia (A. James); Population Health Research Institute, St George's, University of London, United Kingdom (D.P.S.); Department of Medicine, Columbia University Medical Center, New York (W.P.); Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA (E.I.); Data Science Institute and Lancaster Medical School, Lancaster University, United Kingdom (J.K.); and Department of Biostatistics, University of Liverpool, United Kingdom (A.P.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783787PMC
July 2017

Coronary Artery Disease-Associated Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes.

Arterioscler Thromb Vasc Biol 2017 06 9;37(6):1050-1057. Epub 2017 Mar 9.

From the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, United Kingdom.

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http://dx.doi.org/10.1161/ATVBAHA.116.308734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444428PMC
June 2017

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

Authors:
Thomas R Webb Jeanette Erdmann Kathleen E Stirrups Nathan O Stitziel Nicholas G D Masca Henning Jansen Stavroula Kanoni Christopher P Nelson Paola G Ferrario Inke R König John D Eicher Andrew D Johnson Stephen E Hamby Christer Betsholtz Arno Ruusalepp Oscar Franzén Eric E Schadt Johan L M Björkegren Peter E Weeke Paul L Auer Ursula M Schick Yingchang Lu He Zhang Marie-Pierre Dube Anuj Goel Martin Farrall Gina M Peloso Hong-Hee Won Ron Do Erik van Iperen Jochen Kruppa Anubha Mahajan Robert A Scott Christina Willenborg Peter S Braund Julian C van Capelleveen Alex S F Doney Louise A Donnelly Rosanna Asselta Pier A Merlini Stefano Duga Nicola Marziliano Josh C Denny Christian Shaffer Nour Eddine El-Mokhtari Andre Franke Stefanie Heilmann Christian Hengstenberg Per Hoffmann Oddgeir L Holmen Kristian Hveem Jan-Håkan Jansson Karl-Heinz Jöckel Thorsten Kessler Jennifer Kriebel Karl L Laugwitz Eirini Marouli Nicola Martinelli Mark I McCarthy Natalie R Van Zuydam Christa Meisinger Tõnu Esko Evelin Mihailov Stefan A Escher Maris Alver Susanne Moebus Andrew D Morris Jarma Virtamo Majid Nikpay Oliviero Olivieri Sylvie Provost Alaa AlQarawi Neil R Robertson Karen O Akinsansya Dermot F Reilly Thomas F Vogt Wu Yin Folkert W Asselbergs Charles Kooperberg Rebecca D Jackson Eli Stahl Martina Müller-Nurasyid Konstantin Strauch Tibor V Varga Melanie Waldenberger Lingyao Zeng Rajiv Chowdhury Veikko Salomaa Ian Ford J Wouter Jukema Philippe Amouyel Jukka Kontto Børge G Nordestgaard Jean Ferrières Danish Saleheen Naveed Sattar Praveen Surendran Aline Wagner Robin Young Joanna M M Howson Adam S Butterworth John Danesh Diego Ardissino Erwin P Bottinger Raimund Erbel Paul W Franks Domenico Girelli Alistair S Hall G Kees Hovingh Adnan Kastrati Wolfgang Lieb Thomas Meitinger William E Kraus Svati H Shah Ruth McPherson Marju Orho-Melander Olle Melander Andres Metspalu Colin N A Palmer Annette Peters Daniel J Rader Muredach P Reilly Ruth J F Loos Alex P Reiner Dan M Roden Jean-Claude Tardif John R Thompson Nicholas J Wareham Hugh Watkins Cristen J Willer Nilesh J Samani Heribert Schunkert Panos Deloukas Sekar Kathiresan

J Am Coll Cardiol 2017 Feb;69(7):823-836

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts; Department of Medicine, Harvard Medical School, Boston, Massachusetts; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts; Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2016.11.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314135PMC
February 2017

Analysis with the exome array identifies multiple new independent variants in lipid loci.

Hum Mol Genet 2016 09 27;25(18):4094-4106. Epub 2016 Jul 27.

William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK

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http://dx.doi.org/10.1093/hmg/ddw227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291227PMC
September 2016

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease.

N Engl J Med 2016 Jun 18;374(22):2131-41. Epub 2016 May 18.

From deCODE Genetics-Amgen (P.N., A.S., G. Thorleifsson, H. Helgason, A.B.A., G.L.N., A.H., A.M., A.J., S.G., I.J., V.S., T.R., G.M., H. Holm, D.G., P.S., U.T., K.S.), Faculty of Medicine (A.H., I.J., G. Thorgeirsson, U.T., K.S.) and School of Engineering and Natural Sciences (H. Helgason, D.G.), University of Iceland, the Laboratory in Mjodd (G.I.E.), and the Department of Clinical Biochemistry (I.O.) and Division of Cardiology, Department of Internal Medicine (G. Thorgeirsson, H. Holm), Landspitali, National University Hospital of Iceland, Reykjavik, and the Department of Clinical Biochemistry, Akureyri Hospital, Akureyri (O.S.) - all in Iceland; Radboud Institute for Molecular Life Sciences, Department of Laboratory Medicine (D.W.S.), Radboud Institute for Health Sciences (T.E.G., L.A.K.), and the Department of Health Evidence (L.A.K.), Radboud University Medical Center Nijmegen, Nijmegen, the Netherlands; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics (N.G., H.V., T.H., N.T.K., O.P.), and Institute of Public Health, Faculty of Health and Medical Science (T.J., A.L.), University of Copenhagen, and Research Center for Prevention and Health, Capital Region of Denmark (T.J., A.L.), Copenhagen, Faculty of Medicine, University of Aalborg, Aalborg (T.J.), Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.), Department of Public Health, Section of General Practice, University of Aarhus, Aarhus (T.L.), Department of Clinical Experimental Research, Rigshospitalet, Glostrup (A.L.), Department of Clinical Biochemistry, University Hospital of Copenhagen at Hvidovre, Hvidovre (M.F.), Department of Cardiology, Gentofte University Hospital, Hellerup (U.A., P.R.H., A.M.G.), and Department of Cardiology, Roskilde Hospital, Roskilde (A.M.G.) - all in Denmark; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany (N.F.); Department of Cardiovascular Sciences, Uni

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http://dx.doi.org/10.1056/NEJMoa1508419DOI Listing
June 2016

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

Authors:
Nathan O Stitziel Kathleen E Stirrups Nicholas G D Masca Jeanette Erdmann Paola G Ferrario Inke R König Peter E Weeke Thomas R Webb Paul L Auer Ursula M Schick Yingchang Lu He Zhang Marie-Pierre Dube Anuj Goel Martin Farrall Gina M Peloso Hong-Hee Won Ron Do Erik van Iperen Stavroula Kanoni Jochen Kruppa Anubha Mahajan Robert A Scott Christina Willenberg Peter S Braund Julian C van Capelleveen Alex S F Doney Louise A Donnelly Rosanna Asselta Piera A Merlini Stefano Duga Nicola Marziliano Josh C Denny Christian M Shaffer Nour Eddine El-Mokhtari Andre Franke Omri Gottesman Stefanie Heilmann Christian Hengstenberg Per Hoffman Oddgeir L Holmen Kristian Hveem Jan-Håkan Jansson Karl-Heinz Jöckel Thorsten Kessler Jennifer Kriebel Karl L Laugwitz Eirini Marouli Nicola Martinelli Mark I McCarthy Natalie R Van Zuydam Christa Meisinger Tõnu Esko Evelin Mihailov Stefan A Escher Maris Alver Susanne Moebus Andrew D Morris Martina Müller-Nurasyid Majid Nikpay Oliviero Olivieri Louis-Philippe Lemieux Perreault Alaa AlQarawi Neil R Robertson Karen O Akinsanya Dermot F Reilly Thomas F Vogt Wu Yin Folkert W Asselbergs Charles Kooperberg Rebecca D Jackson Eli Stahl Konstantin Strauch Tibor V Varga Melanie Waldenberger Lingyao Zeng Aldi T Kraja Chunyu Liu George B Ehret Christopher Newton-Cheh Daniel I Chasman Rajiv Chowdhury Marco Ferrario Ian Ford J Wouter Jukema Frank Kee Kari Kuulasmaa Børge G Nordestgaard Markus Perola Danish Saleheen Naveed Sattar Praveen Surendran David Tregouet Robin Young Joanna M M Howson Adam S Butterworth John Danesh Diego Ardissino Erwin P Bottinger Raimund Erbel Paul W Franks Domenico Girelli Alistair S Hall G Kees Hovingh Adnan Kastrati Wolfgang Lieb Thomas Meitinger William E Kraus Svati H Shah Ruth McPherson Marju Orho-Melander Olle Melander Andres Metspalu Colin N A Palmer Annette Peters Daniel Rader Muredach P Reilly Ruth J F Loos Alex P Reiner Dan M Roden Jean-Claude Tardif John R Thompson Nicholas J Wareham Hugh Watkins Cristen J Willer Sekkar Kathiresan Panos Deloukas Nilesh J Samani Heribert Schunkert

N Engl J Med 2016 03 2;374(12):1134-44. Epub 2016 Mar 2.

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http://dx.doi.org/10.1056/NEJMoa1507652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850838PMC
March 2016

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

Authors:
Tove Fall Sara Hägg Reedik Mägi Alexander Ploner Krista Fischer Momoko Horikoshi Antti-Pekka Sarin Gudmar Thorleifsson Claes Ladenvall Mart Kals Maris Kuningas Harmen H M Draisma Janina S Ried Natalie R van Zuydam Ville Huikari Massimo Mangino Emily Sonestedt Beben Benyamin Christopher P Nelson Natalia V Rivera Kati Kristiansson Huei-Yi Shen Aki S Havulinna Abbas Dehghan Louise A Donnelly Marika Kaakinen Marja-Liisa Nuotio Neil Robertson Renée F A G de Bruijn M Arfan Ikram Najaf Amin Anthony J Balmforth Peter S Braund Alexander S F Doney Angela Döring Paul Elliott Tõnu Esko Oscar H Franco Solveig Gretarsdottir Anna-Liisa Hartikainen Kauko Heikkilä Karl-Heinz Herzig Hilma Holm Jouke Jan Hottenga Elina Hyppönen Thomas Illig Aaron Isaacs Bo Isomaa Lennart C Karssen Johannes Kettunen Wolfgang Koenig Kari Kuulasmaa Tiina Laatikainen Jaana Laitinen Cecilia Lindgren Valeriya Lyssenko Esa Läärä Nigel W Rayner Satu Männistö Anneli Pouta Wolfgang Rathmann Fernando Rivadeneira Aimo Ruokonen Markku J Savolainen Eric J G Sijbrands Kerrin S Small Jan H Smit Valgerdur Steinthorsdottir Ann-Christine Syvänen Anja Taanila Martin D Tobin Andre G Uitterlinden Sara M Willems Gonneke Willemsen Jacqueline Witteman Markus Perola Alun Evans Jean Ferrières Jarmo Virtamo Frank Kee David-Alexandre Tregouet Dominique Arveiler Philippe Amouyel Marco M Ferrario Paolo Brambilla Alistair S Hall Andrew C Heath Pamela A F Madden Nicholas G Martin Grant W Montgomery John B Whitfield Antti Jula Paul Knekt Ben Oostra Cornelia M van Duijn Brenda W J H Penninx George Davey Smith Jaakko Kaprio Nilesh J Samani Christian Gieger Annette Peters H Erich Wichmann Dorret I Boomsma Eco J C de Geus TiinaMaija Tuomi Chris Power Christopher J Hammond Tim D Spector Lars Lind Marju Orho-Melander Colin Neil Alexander Palmer Andrew D Morris Leif Groop Marjo-Riitta Järvelin Veikko Salomaa Erkki Vartiainen Albert Hofman Samuli Ripatti Andres Metspalu Unnur Thorsteinsdottir Kari Stefansson Nancy L Pedersen Mark I McCarthy Erik Ingelsson Inga Prokopenko

PLoS Med 2013 25;10(6):e1001474. Epub 2013 Jun 25.

Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1001474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692470PMC
March 2014

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

Authors:
Michael V Holmes Tabassome Simon Holly J Exeter Lasse Folkersen Folkert W Asselbergs Montse Guardiola Jackie A Cooper Jutta Palmen Jaroslav A Hubacek Kathryn F Carruthers Benjamin D Horne Kimberly D Brunisholz Jessica L Mega Erik P A van Iperen Mingyao Li Maarten Leusink Stella Trompet Jeffrey J W Verschuren G Kees Hovingh Abbas Dehghan Christopher P Nelson Salma Kotti Nicolas Danchin Markus Scholz Christiane L Haase Dietrich Rothenbacher Daniel I Swerdlow Karoline B Kuchenbaecker Eleonora Staines-Urias Anuj Goel Ferdinand van 't Hooft Karl Gertow Ulf de Faire Andrie G Panayiotou Elena Tremoli Damiano Baldassarre Fabrizio Veglia Lesca M Holdt Frank Beutner Ron T Gansevoort Gerjan J Navis Irene Mateo Leach Lutz P Breitling Hermann Brenner Joachim Thiery Dhayana Dallmeier Anders Franco-Cereceda Jolanda M A Boer Jeffrey W Stephens Marten H Hofker Alain Tedgui Albert Hofman André G Uitterlinden Vera Adamkova Jan Pitha N Charlotte Onland-Moret Maarten J Cramer Hendrik M Nathoe Wilko Spiering Olaf H Klungel Meena Kumari Peter H Whincup David A Morrow Peter S Braund Alistair S Hall Anders G Olsson Pieter A Doevendans Mieke D Trip Martin D Tobin Anders Hamsten Hugh Watkins Wolfgang Koenig Andrew N Nicolaides Daniel Teupser Ian N M Day John F Carlquist Tom R Gaunt Ian Ford Naveed Sattar Sotirios Tsimikas Gregory G Schwartz Debbie A Lawlor Richard W Morris Manjinder S Sandhu Rudolf Poledne Anke H Maitland-van der Zee Kay-Tee Khaw Brendan J Keating Pim van der Harst Jackie F Price Shamir R Mehta Salim Yusuf Jaqueline C M Witteman Oscar H Franco J Wouter Jukema Peter de Knijff Anne Tybjaerg-Hansen Daniel J Rader Martin Farrall Nilesh J Samani Mika Kivimaki Keith A A Fox Steve E Humphries Jeffrey L Anderson S Matthijs Boekholdt Tom M Palmer Per Eriksson Guillaume Paré Aroon D Hingorani Marc S Sabatine Ziad Mallat Juan P Casas Philippa J Talmud

J Am Coll Cardiol 2013 Nov 31;62(21):1966-1976. Epub 2013 Jul 31.

Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2013.06.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826105PMC
November 2013

The 9p21 locus does not affect risk of coronary artery disease through induction of type 1 interferons.

J Am Coll Cardiol 2013 Oct 7;62(15):1376-81. Epub 2013 Aug 7.

Department of Cardiovascular Sciences, University of Leicester, British Heart Foundation Cardiovascular Research Centre, Glenfield Hospital, Leicester, United Kingdom; National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.07.031DOI Listing
October 2013

Identification of seven loci affecting mean telomere length and their association with disease.

Authors:
Veryan Codd Christopher P Nelson Eva Albrecht Massimo Mangino Joris Deelen Jessica L Buxton Jouke Jan Hottenga Krista Fischer Tõnu Esko Ida Surakka Linda Broer Dale R Nyholt Irene Mateo Leach Perttu Salo Sara Hägg Mary K Matthews Jutta Palmen Giuseppe D Norata Paul F O'Reilly Danish Saleheen Najaf Amin Anthony J Balmforth Marian Beekman Rudolf A de Boer Stefan Böhringer Peter S Braund Paul R Burton Anton J M de Craen Matthew Denniff Yanbin Dong Konstantinos Douroudis Elena Dubinina Johan G Eriksson Katia Garlaschelli Dehuang Guo Anna-Liisa Hartikainen Anjali K Henders Jeanine J Houwing-Duistermaat Laura Kananen Lennart C Karssen Johannes Kettunen Norman Klopp Vasiliki Lagou Elisabeth M van Leeuwen Pamela A Madden Reedik Mägi Patrik K E Magnusson Satu Männistö Mark I McCarthy Sarah E Medland Evelin Mihailov Grant W Montgomery Ben A Oostra Aarno Palotie Annette Peters Helen Pollard Anneli Pouta Inga Prokopenko Samuli Ripatti Veikko Salomaa H Eka D Suchiman Ana M Valdes Niek Verweij Ana Viñuela Xiaoling Wang H-Erich Wichmann Elisabeth Widen Gonneke Willemsen Margaret J Wright Kai Xia Xiangjun Xiao Dirk J van Veldhuisen Alberico L Catapano Martin D Tobin Alistair S Hall Alexandra I F Blakemore Wiek H van Gilst Haidong Zhu Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Philippa J Talmud Nancy L Pedersen Markus Perola Willem Ouwehand Jaakko Kaprio Nicholas G Martin Cornelia M van Duijn Iiris Hovatta Christian Gieger Andres Metspalu Dorret I Boomsma Marjo-Riitta Jarvelin P Eline Slagboom John R Thompson Tim D Spector Pim van der Harst Nilesh J Samani

Nat Genet 2013 Apr;45(4):422-7, 427e1-2

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.2528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006270PMC
April 2013

Large-scale association analysis identifies new risk loci for coronary artery disease.

Authors:
Panos Deloukas Stavroula Kanoni Christina Willenborg Martin Farrall Themistocles L Assimes John R Thompson Erik Ingelsson Danish Saleheen Jeanette Erdmann Benjamin A Goldstein Kathleen Stirrups Inke R König Jean-Baptiste Cazier Asa Johansson Alistair S Hall Jong-Young Lee Cristen J Willer John C Chambers Tõnu Esko Lasse Folkersen Anuj Goel Elin Grundberg Aki S Havulinna Weang K Ho Jemma C Hopewell Niclas Eriksson Marcus E Kleber Kati Kristiansson Per Lundmark Leo-Pekka Lyytikäinen Suzanne Rafelt Dmitry Shungin Rona J Strawbridge Gudmar Thorleifsson Emmi Tikkanen Natalie Van Zuydam Benjamin F Voight Lindsay L Waite Weihua Zhang Andreas Ziegler Devin Absher David Altshuler Anthony J Balmforth Inês Barroso Peter S Braund Christof Burgdorf Simone Claudi-Boehm David Cox Maria Dimitriou Ron Do Alex S F Doney NourEddine El Mokhtari Per Eriksson Krista Fischer Pierre Fontanillas Anders Franco-Cereceda Bruna Gigante Leif Groop Stefan Gustafsson Jörg Hager Göran Hallmans Bok-Ghee Han Sarah E Hunt Hyun M Kang Thomas Illig Thorsten Kessler Joshua W Knowles Genovefa Kolovou Johanna Kuusisto Claudia Langenberg Cordelia Langford Karin Leander Marja-Liisa Lokki Anders Lundmark Mark I McCarthy Christa Meisinger Olle Melander Evelin Mihailov Seraya Maouche Andrew D Morris Martina Müller-Nurasyid Kjell Nikus John F Peden N William Rayner Asif Rasheed Silke Rosinger Diana Rubin Moritz P Rumpf Arne Schäfer Mohan Sivananthan Ci Song Alexandre F R Stewart Sian-Tsung Tan Gudmundur Thorgeirsson C Ellen van der Schoot Peter J Wagner George A Wells Philipp S Wild Tsun-Po Yang Philippe Amouyel Dominique Arveiler Hanneke Basart Michael Boehnke Eric Boerwinkle Paolo Brambilla Francois Cambien Adrienne L Cupples Ulf de Faire Abbas Dehghan Patrick Diemert Stephen E Epstein Alun Evans Marco M Ferrario Jean Ferrières Dominique Gauguier Alan S Go Alison H Goodall Villi Gudnason Stanley L Hazen Hilma Holm Carlos Iribarren Yangsoo Jang Mika Kähönen Frank Kee Hyo-Soo Kim Norman Klopp Wolfgang Koenig Wolfgang Kratzer Kari Kuulasmaa Markku Laakso Reijo Laaksonen Ji-Young Lee Lars Lind Willem H Ouwehand Sarah Parish Jeong E Park Nancy L Pedersen Annette Peters Thomas Quertermous Daniel J Rader Veikko Salomaa Eric Schadt Svati H Shah Juha Sinisalo Klaus Stark Kari Stefansson David-Alexandre Trégouët Jarmo Virtamo Lars Wallentin Nicholas Wareham Martina E Zimmermann Markku S Nieminen Christian Hengstenberg Manjinder S Sandhu Tomi Pastinen Ann-Christine Syvänen G Kees Hovingh George Dedoussis Paul W Franks Terho Lehtimäki Andres Metspalu Pierre A Zalloua Agneta Siegbahn Stefan Schreiber Samuli Ripatti Stefan S Blankenberg Markus Perola Robert Clarke Bernhard O Boehm Christopher O'Donnell Muredach P Reilly Winfried März Rory Collins Sekar Kathiresan Anders Hamsten Jaspal S Kooner Unnur Thorsteinsdottir John Danesh Colin N A Palmer Robert Roberts Hugh Watkins Heribert Schunkert Nilesh J Samani

Nat Genet 2013 Jan 2;45(1):25-33. Epub 2012 Dec 2.

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http://dx.doi.org/10.1038/ng.2480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679547PMC
January 2013

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Authors:
Folkert W Asselbergs Yiran Guo Erik P A van Iperen Suthesh Sivapalaratnam Vinicius Tragante Matthew B Lanktree Leslie A Lange Berta Almoguera Yolande E Appelman John Barnard Jens Baumert Amber L Beitelshees Tushar R Bhangale Yii-Der Ida Chen Tom R Gaunt Yan Gong Jemma C Hopewell Toby Johnson Marcus E Kleber Taimour Y Langaee Mingyao Li Yun R Li Kiang Liu Caitrin W McDonough Matthijs F L Meijs Rita P S Middelberg Kiran Musunuru Christopher P Nelson Jeffery R O'Connell Sandosh Padmanabhan James S Pankow Nathan Pankratz Suzanne Rafelt Ramakrishnan Rajagopalan Simon P R Romaine Nicholas J Schork Jonathan Shaffer Haiqing Shen Erin N Smith Sam E Tischfield Peter J van der Most Jana V van Vliet-Ostaptchouk Niek Verweij Kelly A Volcik Li Zhang Kent R Bailey Kristian M Bailey Florianne Bauer Jolanda M A Boer Peter S Braund Amber Burt Paul R Burton Sarah G Buxbaum Wei Chen Rhonda M Cooper-Dehoff L Adrienne Cupples Jonas S deJong Christian Delles David Duggan Myriam Fornage Clement E Furlong Nicole Glazer John G Gums Claire Hastie Michael V Holmes Thomas Illig Susan A Kirkland Mika Kivimaki Ronald Klein Barbara E Klein Charles Kooperberg Kandice Kottke-Marchant Meena Kumari Andrea Z LaCroix Laya Mallela Gurunathan Murugesan Jose Ordovas Willem H Ouwehand Wendy S Post Richa Saxena Hubert Scharnagl Pamela J Schreiner Tina Shah Denis C Shields Daichi Shimbo Sathanur R Srinivasan Ronald P Stolk Daniel I Swerdlow Herman A Taylor Eric J Topol Elina Toskala Joost L van Pelt Jessica van Setten Salim Yusuf John C Whittaker A H Zwinderman Sonia S Anand Anthony J Balmforth Gerald S Berenson Connie R Bezzina Bernhard O Boehm Eric Boerwinkle Juan P Casas Mark J Caulfield Robert Clarke John M Connell Karen J Cruickshanks Karina W Davidson Ian N M Day Paul I W de Bakker Pieter A Doevendans Anna F Dominiczak Alistair S Hall Catharina A Hartman Christian Hengstenberg Hans L Hillege Marten H Hofker Steve E Humphries Gail P Jarvik Julie A Johnson Bernhard M Kaess Sekar Kathiresan Wolfgang Koenig Debbie A Lawlor Winfried März Olle Melander Braxton D Mitchell Grant W Montgomery Patricia B Munroe Sarah S Murray Stephen J Newhouse N Charlotte Onland-Moret Neil Poulter Bruce Psaty Susan Redline Stephen S Rich Jerome I Rotter Heribert Schunkert Peter Sever Alan R Shuldiner Roy L Silverstein Alice Stanton Barbara Thorand Mieke D Trip Michael Y Tsai Pim van der Harst Ellen van der Schoot Yvonne T van der Schouw W M Monique Verschuren Hugh Watkins Arthur A M Wilde Bruce H R Wolffenbuttel John B Whitfield G Kees Hovingh Christie M Ballantyne Cisca Wijmenga Muredach P Reilly Nicholas G Martin James G Wilson Daniel J Rader Nilesh J Samani Alex P Reiner Robert A Hegele John J P Kastelein Aroon D Hingorani Philippa J Talmud Hakon Hakonarson Clara C Elbers Brendan J Keating Fotios Drenos

Am J Hum Genet 2012 Nov 11;91(5):823-38. Epub 2012 Oct 11.

Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2012.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487124PMC
November 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Authors:
Richa Saxena Clara C Elbers Yiran Guo Inga Peter Tom R Gaunt Jessica L Mega Matthew B Lanktree Archana Tare Berta Almoguera Castillo Yun R Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F Voight Ashok Balasubramanyam John Barnard Florianne Bauer Jens Baumert Tushar Bhangale Bernhard O Böhm Peter S Braund Paul R Burton Hareesh R Chandrupatla Robert Clarke Rhonda M Cooper-DeHoff Errol D Crook George Davey-Smith Ian N Day Anthonius de Boer Mark C H de Groot Fotios Drenos Jane Ferguson Caroline S Fox Clement E Furlong Quince Gibson Christian Gieger Lisa A Gilhuijs-Pederson Joseph T Glessner Anuj Goel Yan Gong Struan F A Grant Diederick E Grobbee Claire Hastie Steve E Humphries Cecilia E Kim Mika Kivimaki Marcus Kleber Christa Meisinger Meena Kumari Taimour Y Langaee Debbie A Lawlor Mingyao Li Maximilian T Lobmeyer Anke-Hilse Maitland-van der Zee Matthijs F L Meijs Cliona M Molony David A Morrow Gurunathan Murugesan Solomon K Musani Christopher P Nelson Stephen J Newhouse Jeffery R O'Connell Sandosh Padmanabhan Jutta Palmen Sanjey R Patel Carl J Pepine Mary Pettinger Thomas S Price Suzanne Rafelt Jane Ranchalis Asif Rasheed Elisabeth Rosenthal Ingo Ruczinski Sonia Shah Haiqing Shen Günther Silbernagel Erin N Smith Annemieke W M Spijkerman Alice Stanton Michael W Steffes Barbara Thorand Mieke Trip Pim van der Harst Daphne L van der A Erik P A van Iperen Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Bruce H R Wolffenbuttel Taylor Young M Hadi Zafarmand Joseph M Zmuda Michael Boehnke David Altshuler Mark McCarthy W H Linda Kao James S Pankow Thomas P Cappola Peter Sever Neil Poulter Mark Caulfield Anna Dominiczak Denis C Shields Deepak L Bhatt Deepak Bhatt Li Zhang Sean P Curtis John Danesh Juan P Casas Yvonne T van der Schouw N Charlotte Onland-Moret Pieter A Doevendans Gerald W Dorn Martin Farrall Garret A FitzGerald Anders Hamsten Robert Hegele Aroon D Hingorani Marten H Hofker Gordon S Huggins Thomas Illig Gail P Jarvik Julie A Johnson Olaf H Klungel William C Knowler Wolfgang Koenig Winfried März James B Meigs Olle Melander Patricia B Munroe Braxton D Mitchell Susan J Bielinski Daniel J Rader Muredach P Reilly Stephen S Rich Jerome I Rotter Danish Saleheen Nilesh J Samani Eric E Schadt Alan R Shuldiner Roy Silverstein Kandice Kottke-Marchant Philippa J Talmud Hugh Watkins Folkert W Asselbergs Folkert Asselbergs Paul I W de Bakker Jeanne McCaffery Cisca Wijmenga Marc S Sabatine James G Wilson Alex Reiner Donald W Bowden Hakon Hakonarson David S Siscovick Brendan J Keating

Am J Hum Genet 2012 Mar 9;90(3):410-25. Epub 2012 Feb 9.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309185PMC
March 2012

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.

Authors:
Nadeem Sarwar Adam S Butterworth Daniel F Freitag John Gregson Peter Willeit Donal N Gorman Pei Gao Danish Saleheen Augusto Rendon Christopher P Nelson Peter S Braund Alistair S Hall Daniel I Chasman Anne Tybjærg-Hansen John C Chambers Emelia J Benjamin Paul W Franks Robert Clarke Arthur A M Wilde Mieke D Trip Maristella Steri Jacqueline C M Witteman Lu Qi C Ellen van der Schoot Ulf de Faire Jeanette Erdmann Heather M Stringham Wolfgang Koenig Daniel J Rader David Melzer David Reich Bruce M Psaty Marcus E Kleber Demosthenes B Panagiotakos Johann Willeit Patrik Wennberg Mark Woodward Svetlana Adamovic Eric B Rimm Tom W Meade Richard F Gillum Jonathan A Shaffer Albert Hofman Altan Onat Johan Sundström Sylvia Wassertheil-Smoller Dan Mellström John Gallacher Mary Cushman Russell P Tracy Jussi Kauhanen Magnus Karlsson Jukka T Salonen Lars Wilhelmsen Philippe Amouyel Bernard Cantin Lyle G Best Yoav Ben-Shlomo JoAnn E Manson George Davey-Smith Paul I W de Bakker Christopher J O'Donnell James F Wilson Anthony G Wilson Themistocles L Assimes John-Olov Jansson Claes Ohlsson Åsa Tivesten Östen Ljunggren Muredach P Reilly Anders Hamsten Erik Ingelsson Francois Cambien Joseph Hung G Neil Thomas Michael Boehnke Heribert Schunkert Folkert W Asselbergs John J P Kastelein Vilmundur Gudnason Veikko Salomaa Tamara B Harris Jaspal S Kooner Kristine H Allin Børge G Nordestgaard Jemma C Hopewell Alison H Goodall Paul M Ridker Hilma Hólm Hugh Watkins Willem H Ouwehand Nilesh J Samani Stephen Kaptoge Emanuele Di Angelantonio Olivier Harari John Danesh

Blood pressure loci identified with a gene-centric array.

Authors:
Toby Johnson Tom R Gaunt Stephen J Newhouse Sandosh Padmanabhan Maciej Tomaszewski Meena Kumari Richard W Morris Ioanna Tzoulaki Eoin T O'Brien Neil R Poulter Peter Sever Denis C Shields Simon Thom Sasiwarang G Wannamethee Peter H Whincup Morris J Brown John M Connell Richard J Dobson Philip J Howard Charles A Mein Abiodun Onipinla Sue Shaw-Hawkins Yun Zhang George Davey Smith Ian N M Day Debbie A Lawlor Alison H Goodall F Gerald Fowkes Gonçalo R Abecasis Paul Elliott Vesela Gateva Peter S Braund Paul R Burton Christopher P Nelson Martin D Tobin Pim van der Harst Nicola Glorioso Hani Neuvrith Erika Salvi Jan A Staessen Andrea Stucchi Nabila Devos Xavier Jeunemaitre Pierre-François Plouin Jean Tichet Peeter Juhanson Elin Org Margus Putku Siim Sõber Gudrun Veldre Margus Viigimaa Anna Levinsson Annika Rosengren Dag S Thelle Claire E Hastie Thomas Hedner Wai K Lee Olle Melander Björn Wahlstrand Rebecca Hardy Andrew Wong Jackie A Cooper Jutta Palmen Li Chen Alexandre F R Stewart George A Wells Harm-Jan Westra Marcel G M Wolfs Robert Clarke Maria Grazia Franzosi Anuj Goel Anders Hamsten Mark Lathrop John F Peden Udo Seedorf Hugh Watkins Willem H Ouwehand Jennifer Sambrook Jonathan Stephens Juan-Pablo Casas Fotios Drenos Michael V Holmes Mika Kivimaki Sonia Shah Tina Shah Philippa J Talmud John Whittaker Chris Wallace Christian Delles Maris Laan Diana Kuh Steve E Humphries Fredrik Nyberg Daniele Cusi Robert Roberts Christopher Newton-Cheh Lude Franke Alice V Stanton Anna F Dominiczak Martin Farrall Aroon D Hingorani Nilesh J Samani Mark J Caulfield Patricia B Munroe

Am J Hum Genet 2011 Dec 17;89(6):688-700. Epub 2011 Nov 17.

Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234370PMC
December 2011

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Authors:
Georg B Ehret Patricia B Munroe Kenneth M Rice Murielle Bochud Andrew D Johnson Daniel I Chasman Albert V Smith Martin D Tobin Germaine C Verwoert Shih-Jen Hwang Vasyl Pihur Peter Vollenweider Paul F O'Reilly Najaf Amin Jennifer L Bragg-Gresham Alexander Teumer Nicole L Glazer Lenore Launer Jing Hua Zhao Yurii Aulchenko Simon Heath Siim Sõber Afshin Parsa Jian'an Luan Pankaj Arora Abbas Dehghan Feng Zhang Gavin Lucas Andrew A Hicks Anne U Jackson John F Peden Toshiko Tanaka Sarah H Wild Igor Rudan Wilmar Igl Yuri Milaneschi Alex N Parker Cristiano Fava John C Chambers Ervin R Fox Meena Kumari Min Jin Go Pim van der Harst Wen Hong Linda Kao Marketa Sjögren D G Vinay Myriam Alexander Yasuharu Tabara Sue Shaw-Hawkins Peter H Whincup Yongmei Liu Gang Shi Johanna Kuusisto Bamidele Tayo Mark Seielstad Xueling Sim Khanh-Dung Hoang Nguyen Terho Lehtimäki Giuseppe Matullo Ying Wu Tom R Gaunt N Charlotte Onland-Moret Matthew N Cooper Carl G P Platou Elin Org Rebecca Hardy Santosh Dahgam Jutta Palmen Veronique Vitart Peter S Braund Tatiana Kuznetsova Cuno S P M Uiterwaal Adebowale Adeyemo Walter Palmas Harry Campbell Barbara Ludwig Maciej Tomaszewski Ioanna Tzoulaki Nicholette D Palmer Thor Aspelund Melissa Garcia Yen-Pei C Chang Jeffrey R O'Connell Nanette I Steinle Diederick E Grobbee Dan E Arking Sharon L Kardia Alanna C Morrison Dena Hernandez Samer Najjar Wendy L McArdle David Hadley Morris J Brown John M Connell Aroon D Hingorani Ian N M Day Debbie A Lawlor John P Beilby Robert W Lawrence Robert Clarke Jemma C Hopewell Halit Ongen Albert W Dreisbach Yali Li J Hunter Young Joshua C Bis Mika Kähönen Jorma Viikari Linda S Adair Nanette R Lee Ming-Huei Chen Matthias Olden Cristian Pattaro Judith A Hoffman Bolton Anna Köttgen Sven Bergmann Vincent Mooser Nish Chaturvedi Timothy M Frayling Muhammad Islam Tazeen H Jafar Jeanette Erdmann Smita R Kulkarni Stefan R Bornstein Jürgen Grässler Leif Groop Benjamin F Voight Johannes Kettunen Philip Howard Andrew Taylor Simonetta Guarrera Fulvio Ricceri Valur Emilsson Andrew Plump Inês Barroso Kay-Tee Khaw Alan B Weder Steven C Hunt Yan V Sun Richard N Bergman Francis S Collins Lori L Bonnycastle Laura J Scott Heather M Stringham Leena Peltonen Markus Perola Erkki Vartiainen Stefan-Martin Brand Jan A Staessen Thomas J Wang Paul R Burton Maria Soler Artigas Yanbin Dong Harold Snieder Xiaoling Wang Haidong Zhu Kurt K Lohman Megan E Rudock Susan R Heckbert Nicholas L Smith Kerri L Wiggins Ayo Doumatey Daniel Shriner Gudrun Veldre Margus Viigimaa Sanjay Kinra Dorairaj Prabhakaran Vikal Tripathy Carl D Langefeld Annika Rosengren Dag S Thelle Anna Maria Corsi Andrew Singleton Terrence Forrester Gina Hilton Colin A McKenzie Tunde Salako Naoharu Iwai Yoshikuni Kita Toshio Ogihara Takayoshi Ohkubo Tomonori Okamura Hirotsugu Ueshima Satoshi Umemura Susana Eyheramendy Thomas Meitinger H-Erich Wichmann Yoon Shin Cho Hyung-Lae Kim Jong-Young Lee James Scott Joban S Sehmi Weihua Zhang Bo Hedblad Peter Nilsson George Davey Smith Andrew Wong Narisu Narisu Alena Stančáková Leslie J Raffel Jie Yao Sekar Kathiresan Christopher J O'Donnell Stephen M Schwartz M Arfan Ikram W T Longstreth Thomas H Mosley Sudha Seshadri Nick R G Shrine Louise V Wain Mario A Morken Amy J Swift Jaana Laitinen Inga Prokopenko Paavo Zitting Jackie A Cooper Steve E Humphries John Danesh Asif Rasheed Anuj Goel Anders Hamsten Hugh Watkins Stephan J L Bakker Wiek H van Gilst Charles S Janipalli K Radha Mani Chittaranjan S Yajnik Albert Hofman Francesco U S Mattace-Raso Ben A Oostra Ayse Demirkan Aaron Isaacs Fernando Rivadeneira Edward G Lakatta Marco Orru Angelo Scuteri Mika Ala-Korpela Antti J Kangas Leo-Pekka Lyytikäinen Pasi Soininen Taru Tukiainen Peter Würtz Rick Twee-Hee Ong Marcus Dörr Heyo K Kroemer Uwe Völker Henry Völzke Pilar Galan Serge Hercberg Mark Lathrop Diana Zelenika Panos Deloukas Massimo Mangino Tim D Spector Guangju Zhai James F Meschia Michael A Nalls Pankaj Sharma Janos Terzic M V Kranthi Kumar Matthew Denniff Ewa Zukowska-Szczechowska Lynne E Wagenknecht F Gerald R Fowkes Fadi J Charchar Peter E H Schwarz Caroline Hayward Xiuqing Guo Charles Rotimi Michiel L Bots Eva Brand Nilesh J Samani Ozren Polasek Philippa J Talmud Fredrik Nyberg Diana Kuh Maris Laan Kristian Hveem Lyle J Palmer Yvonne T van der Schouw Juan P Casas Karen L Mohlke Paolo Vineis Olli Raitakari Santhi K Ganesh Tien Y Wong E Shyong Tai Richard S Cooper Markku Laakso Dabeeru C Rao Tamara B Harris Richard W Morris Anna F Dominiczak Mika Kivimaki Michael G Marmot Tetsuro Miki Danish Saleheen Giriraj R Chandak Josef Coresh Gerjan Navis Veikko Salomaa Bok-Ghee Han Xiaofeng Zhu Jaspal S Kooner Olle Melander Paul M Ridker Stefania Bandinelli Ulf B Gyllensten Alan F Wright James F Wilson Luigi Ferrucci Martin Farrall Jaakko Tuomilehto Peter P Pramstaller Roberto Elosua Nicole Soranzo Eric J G Sijbrands David Altshuler Ruth J F Loos Alan R Shuldiner Christian Gieger Pierre Meneton Andre G Uitterlinden Nicholas J Wareham Vilmundur Gudnason Jerome I Rotter Rainer Rettig Manuela Uda David P Strachan Jacqueline C M Witteman Anna-Liisa Hartikainen Jacques S Beckmann Eric Boerwinkle Ramachandran S Vasan Michael Boehnke Martin G Larson Marjo-Riitta Järvelin Bruce M Psaty Gonçalo R Abecasis Aravinda Chakravarti Paul Elliott Cornelia M van Duijn Christopher Newton-Cheh Daniel Levy Mark J Caulfield Toby Johnson

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

Circ Cardiovasc Genet 2011 Aug 23;4(4):403-12. Epub 2011 May 23.

Department of Medicine II, University Medical Center Mainz, Germany.

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http://dx.doi.org/10.1161/CIRCGENETICS.110.958728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157552PMC
August 2011

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Authors:
Heribert Schunkert Inke R König Sekar Kathiresan Muredach P Reilly Themistocles L Assimes Hilma Holm Michael Preuss Alexandre F R Stewart Maja Barbalic Christian Gieger Devin Absher Zouhair Aherrahrou Hooman Allayee David Altshuler Sonia S Anand Karl Andersen Jeffrey L Anderson Diego Ardissino Stephen G Ball Anthony J Balmforth Timothy A Barnes Diane M Becker Lewis C Becker Klaus Berger Joshua C Bis S Matthijs Boekholdt Eric Boerwinkle Peter S Braund Morris J Brown Mary Susan Burnett Ian Buysschaert John F Carlquist Li Chen Sven Cichon Veryan Codd Robert W Davies George Dedoussis Abbas Dehghan Serkalem Demissie Joseph M Devaney Patrick Diemert Ron Do Angela Doering Sandra Eifert Nour Eddine El Mokhtari Stephen G Ellis Roberto Elosua James C Engert Stephen E Epstein Ulf de Faire Marcus Fischer Aaron R Folsom Jennifer Freyer Bruna Gigante Domenico Girelli Solveig Gretarsdottir Vilmundur Gudnason Jeffrey R Gulcher Eran Halperin Naomi Hammond Stanley L Hazen Albert Hofman Benjamin D Horne Thomas Illig Carlos Iribarren Gregory T Jones J Wouter Jukema Michael A Kaiser Lee M Kaplan John J P Kastelein Kay-Tee Khaw Joshua W Knowles Genovefa Kolovou Augustine Kong Reijo Laaksonen Diether Lambrechts Karin Leander Guillaume Lettre Mingyao Li Wolfgang Lieb Christina Loley Andrew J Lotery Pier M Mannucci Seraya Maouche Nicola Martinelli Pascal P McKeown Christa Meisinger Thomas Meitinger Olle Melander Pier Angelica Merlini Vincent Mooser Thomas Morgan Thomas W Mühleisen Joseph B Muhlestein Thomas Münzel Kiran Musunuru Janja Nahrstaedt Christopher P Nelson Markus M Nöthen Oliviero Olivieri Riyaz S Patel Chris C Patterson Annette Peters Flora Peyvandi Liming Qu Arshed A Quyyumi Daniel J Rader Loukianos S Rallidis Catherine Rice Frits R Rosendaal Diana Rubin Veikko Salomaa M Lourdes Sampietro Manj S Sandhu Eric Schadt Arne Schäfer Arne Schillert Stefan Schreiber Jürgen Schrezenmeir Stephen M Schwartz David S Siscovick Mohan Sivananthan Suthesh Sivapalaratnam Albert Smith Tamara B Smith Jaapjan D Snoep Nicole Soranzo John A Spertus Klaus Stark Kathy Stirrups Monika Stoll W H Wilson Tang Stephanie Tennstedt Gudmundur Thorgeirsson Gudmar Thorleifsson Maciej Tomaszewski Andre G Uitterlinden Andre M van Rij Benjamin F Voight Nick J Wareham George A Wells H-Erich Wichmann Philipp S Wild Christina Willenborg Jaqueline C M Witteman Benjamin J Wright Shu Ye Tanja Zeller Andreas Ziegler Francois Cambien Alison H Goodall L Adrienne Cupples Thomas Quertermous Winfried März Christian Hengstenberg Stefan Blankenberg Willem H Ouwehand Alistair S Hall Panos Deloukas John R Thompson Kari Stefansson Robert Roberts Unnur Thorsteinsdottir Christopher J O'Donnell Ruth McPherson Jeanette Erdmann Nilesh J Samani

Nat Genet 2011 Mar 6;43(4):333-8. Epub 2011 Mar 6.

Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany.

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http://dx.doi.org/10.1038/ng.784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119261PMC
March 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2010.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014369PMC
January 2011

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.

Authors:
Themistocles L Assimes Hilma Hólm Sekar Kathiresan Muredach P Reilly Gudmar Thorleifsson Benjamin F Voight Jeanette Erdmann Christina Willenborg Dhananjay Vaidya Changchun Xie Chris C Patterson Thomas M Morgan Mary Susan Burnett Mingyao Li Mark A Hlatky Joshua W Knowles John R Thompson Devin Absher Carlos Iribarren Alan Go Stephen P Fortmann Stephen Sidney Neil Risch Hua Tang Richard M Myers Klaus Berger Monika Stoll Svati H Shah Gudmundur Thorgeirsson Karl Andersen Aki S Havulinna J Enrique Herrera Nauder Faraday Yoonhee Kim Brian G Kral Rasika A Mathias Ingo Ruczinski Bhoom Suktitipat Alexander F Wilson Lisa R Yanek Lewis C Becker Patrick Linsel-Nitschke Wolfgang Lieb Inke R König Christian Hengstenberg Marcus Fischer Klaus Stark Wibke Reinhard Janina Winogradow Martina Grassl Anika Grosshennig Michael Preuss Stefan Schreiber H-Erich Wichmann Christa Meisinger Jean Yee Yechiel Friedlander Ron Do James B Meigs Gordon Williams David M Nathan Calum A MacRae Liming Qu Robert L Wilensky William H Matthai Atif N Qasim Hakon Hakonarson Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Christopher W Knouff Dawn M Waterworth Max C Walker Vincent E Mooser Jaume Marrugat Gavin Lucas Isaac Subirana Joan Sala Rafael Ramos Nicola Martinelli Oliviero Olivieri Elisabetta Trabetti Giovanni Malerba Pier Franco Pignatti Candace Guiducci Daniel Mirel Melissa Parkin Joel N Hirschhorn Rosanna Asselta Stefano Duga Kiran Musunuru Mark J Daly Shaun Purcell Sandra Eifert Peter S Braund Benjamin J Wright Anthony J Balmforth Stephen G Ball Willem H Ouwehand Panos Deloukas Michael Scholz Francois Cambien Andreas Huge Thomas Scheffold Veikko Salomaa Domenico Girelli Christopher B Granger Leena Peltonen Pascal P McKeown David Altshuler Olle Melander Joseph M Devaney Stephen E Epstein Daniel J Rader Roberto Elosua James C Engert Sonia S Anand Alistair S Hall Andreas Ziegler Christopher J O'Donnell John A Spertus David Siscovick Stephen M Schwartz Diane Becker Unnur Thorsteinsdottir Kari Stefansson Heribert Schunkert Nilesh J Samani Thomas Quertermous

J Am Coll Cardiol 2010 Nov;56(19):1552-63

Department of Medicine, Stanford University School of Medicine, Stanford, California 94304-1334, USA.

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http://dx.doi.org/10.1016/j.jacc.2010.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084526PMC
November 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

Authors:
Sekar Kathiresan Benjamin F Voight Shaun Purcell Kiran Musunuru Diego Ardissino Pier M Mannucci Sonia Anand James C Engert Nilesh J Samani Heribert Schunkert Jeanette Erdmann Muredach P Reilly Daniel J Rader Thomas Morgan John A Spertus Monika Stoll Domenico Girelli Pascal P McKeown Chris C Patterson David S Siscovick Christopher J O'Donnell Roberto Elosua Leena Peltonen Veikko Salomaa Stephen M Schwartz Olle Melander David Altshuler Diego Ardissino Pier Angelica Merlini Carlo Berzuini Luisa Bernardinelli Flora Peyvandi Marco Tubaro Patrizia Celli Maurizio Ferrario Raffaela Fetiveau Nicola Marziliano Giorgio Casari Michele Galli Flavio Ribichini Marco Rossi Francesco Bernardi Pietro Zonzin Alberto Piazza Pier M Mannucci Stephen M Schwartz David S Siscovick Jean Yee Yechiel Friedlander Roberto Elosua Jaume Marrugat Gavin Lucas Isaac Subirana Joan Sala Rafael Ramos Sekar Kathiresan James B Meigs Gordon Williams David M Nathan Calum A MacRae Christopher J O'Donnell Veikko Salomaa Aki S Havulinna Leena Peltonen Olle Melander Goran Berglund Benjamin F Voight Sekar Kathiresan Joel N Hirschhorn Rosanna Asselta Stefano Duga Marta Spreafico Kiran Musunuru Mark J Daly Shaun Purcell Benjamin F Voight Shaun Purcell James Nemesh Joshua M Korn Steven A McCarroll Stephen M Schwartz Jean Yee Sekar Kathiresan Gavin Lucas Isaac Subirana Roberto Elosua Aarti Surti Candace Guiducci Lauren Gianniny Daniel Mirel Melissa Parkin Noel Burtt Stacey B Gabriel Nilesh J Samani John R Thompson Peter S Braund Benjamin J Wright Anthony J Balmforth Stephen G Ball Alistair S Hall Heribert Schunkert Jeanette Erdmann Patrick Linsel-Nitschke Wolfgang Lieb Andreas Ziegler Inke König Christian Hengstenberg Marcus Fischer Klaus Stark Anika Grosshennig Michael Preuss H-Erich Wichmann Stefan Schreiber Heribert Schunkert Nilesh J Samani Jeanette Erdmann Willem Ouwehand Christian Hengstenberg Panos Deloukas Michael Scholz Francois Cambien Muredach P Reilly Mingyao Li Zhen Chen Robert Wilensky William Matthai Atif Qasim Hakon H Hakonarson Joe Devaney Mary-Susan Burnett Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Christopher W Knouff Dawn M Waterworth Max C Walker Vincent Mooser Stephen E Epstein Daniel J Rader Thomas Scheffold Klaus Berger Monika Stoll Andreas Huge Domenico Girelli Nicola Martinelli Oliviero Olivieri Roberto Corrocher Thomas Morgan John A Spertus Pascal McKeown Chris C Patterson Heribert Schunkert Erdmann Erdmann Patrick Linsel-Nitschke Wolfgang Lieb Andreas Ziegler Inke R König Christian Hengstenberg Marcus Fischer Klaus Stark Anika Grosshennig Michael Preuss H-Erich Wichmann Stefan Schreiber Hilma Hólm Gudmar Thorleifsson Unnur Thorsteinsdottir Kari Stefansson James C Engert Ron Do Changchun Xie Sonia Anand Sekar Kathiresan Diego Ardissino Pier M Mannucci David Siscovick Christopher J O'Donnell Nilesh J Samani Olle Melander Roberto Elosua Leena Peltonen Veikko Salomaa Stephen M Schwartz David Altshuler

Nat Genet 2009 Mar 8;41(3):334-41. Epub 2009 Feb 8.

Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/ng.327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681011PMC
March 2009

Association between the coronary artery disease risk locus on chromosome 9p21.3 and abdominal aortic aneurysm.

Circ Cardiovasc Genet 2008 Oct;1(1):39-42

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1161/CIRCGENETICS.108.789727DOI Listing
October 2008

Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodium-related blood pressure regulation.

Hypertension 2008 Aug 30;52(2):366-72. Epub 2008 Jun 30.

Division of Nephrology, Dialysis, and Hypertension, University "Vita-Salute" San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.108.113977DOI Listing
August 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study.

Eur Heart J 2004 Mar;25(6):459-67

Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, UK.

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http://eurheartj.oxfordjournals.org/content/ehj/25/6/459.ful
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http://eurheartj.oxfordjournals.org/cgi/doi/10.1016/j.ehj.20
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http://dx.doi.org/10.1016/j.ehj.2003.11.014DOI Listing
March 2004