Peter Rothwell

Peter Rothwell

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Peter Rothwell

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Effect of coexisting vascular disease on long-term risk of recurrent events after TIA or stroke.

Neurology 2019 Aug 23;93(7):e695-e707. Epub 2019 Jul 23.

From the Centre for Prevention of Stroke and Dementia (M.B., L.L., S.L., N.G.L., M.M.K., L.S., P.M.R.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, UK; and Service de Neurologie (M.B., E.T.), CHU Caen Normandie, UNICAEN, Normandie Université, INSERM U1237, Caen, France.

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http://dx.doi.org/10.1212/WNL.0000000000007935DOI Listing
August 2019

Sex Differences in Long-Term Quality of Life Among Survivors After Stroke in the INSTRUCT.

Stroke 2019 Aug 15:STROKEAHA118024437. Epub 2019 Aug 15.

From the Menzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia (H.T.P., C.L.B., P.O., S.G.).

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http://dx.doi.org/10.1161/STROKEAHA.118.024437DOI Listing
August 2019

Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT.

Health Technol Assess 2019 Aug;23(41):1-30

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.3310/hta23410DOI Listing
August 2019

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Authors:
Duncan Wilson Gareth Ambler Keon-Joo Lee Jae-Sung Lim Masayuki Shiozawa Masatoshi Koga Linxin Li Caroline Lovelock Hugues Chabriat Michael Hennerici Yuen Kwun Wong Henry Ka Fung Mak Luis Prats-Sánchez Alejandro Martínez-Domeño Shigeru Inamura Kazuhisa Yoshifuji Ethem Murat Arsava Solveig Horstmann Jan Purrucker Bonnie Yin Ka Lam Adrian Wong Young Dae Kim Tae-Jin Song Maarten Schrooten Robin Lemmens Sebastian Eppinger Thomas Gattringer Ender Uysal Zeynep Tanriverdi Natan M Bornstein Einor Ben Assayag Hen Hallevi Jun Tanaka Hideo Hara Shelagh B Coutts Lisa Hert Alexandros Polymeris David J Seiffge Philippe Lyrer Ale Algra Jaap Kappelle Rustam Al-Shahi Salman Hans R Jäger Gregory Y H Lip Heinrich P Mattle Leonidas D Panos Jean-Louis Mas Laurence Legrand Christopher Karayiannis Thanh Phan Sarah Gunkel Nicolas Christ Jill Abrigo Thomas Leung Winnie Chu Francesca Chappell Stephen Makin Derek Hayden David J Williams M Eline Kooi Dianne H K van Dam-Nolen Carmen Barbato Simone Browning Kim Wiegertjes Anil M Tuladhar Noortje Maaijwee Christine Guevarra Chathuri Yatawara Anne-Marie Mendyk Christine Delmaire Sebastian Köhler Robert van Oostenbrugge Ying Zhou Chao Xu Saima Hilal Bibek Gyanwali Christopher Chen Min Lou Julie Staals Régis Bordet Nagaendran Kandiah Frank-Erik de Leeuw Robert Simister Aad van der Lugt Peter J Kelly Joanna M Wardlaw Yannie Soo Felix Fluri Velandai Srikanth David Calvet Simon Jung Vincent I H Kwa Stefan T Engelter Nils Peters Eric E Smith Yusuke Yakushiji Dilek Necioglu Orken Franz Fazekas Vincent Thijs Ji Hoe Heo Vincent Mok Roland Veltkamp Hakan Ay Toshio Imaizumi Beatriz Gomez-Anson Kui Kai Lau Eric Jouvent Peter M Rothwell Kazunori Toyoda Hee-Joon Bae Joan Marti-Fabregas David J Werring

Lancet Neurol 2019 Jul 23;18(7):653-665. Epub 2019 May 23.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30197-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562236PMC
July 2019

Stenting for symptomatic vertebral artery stenosis: a preplanned pooled individual patient data analysis.

Lancet Neurol 2019 Jul 23;18(7):666-673. Epub 2019 May 23.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center, Utrecht University, Utrecht, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht University, Utrecht, Netherlands.

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http://dx.doi.org/10.1016/S1474-4422(19)30149-8DOI Listing
July 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-019-0449-0DOI Listing
July 2019

Age-dependent association of white matter abnormality with cognition after TIA or minor stroke.

Neurology 2019 Jul 14;93(3):e272-e282. Epub 2019 Jun 14.

From the Centre for Prevention of Stroke and Dementia (G.Z., L.G., S.M., S.T.P., P.M.R.) and Wellcome Centre for Integrative Neuroimaging, FMRIB (G.Z., L.G.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford; and Department of Biomedical, Metabolic and Neural Sciences and Centre for Neurosciences and Neurotechnology (G.Z.), University of Modena and Reggio Emilia, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000007772DOI Listing
July 2019

Sensitivity of Administrative Coding in Identifying Inpatient Acute Strokes Complicating Procedures or Other Diseases in UK Hospitals.

J Am Heart Assoc 2019 Jul 3;8(14):e012995. Epub 2019 Jul 3.

1 Centre for Prevention of Stroke and Dementia Nuffield Department of Clinical Neuroscience University of Oxford United Kingdom.

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http://dx.doi.org/10.1161/JAHA.119.012995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662118PMC
July 2019

Long-Term Risk of Stroke After Transient Global Amnesia in Two Prospective Cohorts.

Stroke 2019 Jul 9:STROKEAHA119025720. Epub 2019 Jul 9.

From the Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neuroscience, University of Oxford, United Kingdom (M.R., M.A.T., I.M., L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025720DOI Listing
July 2019

Automated lesion segmentation with BIANCA: Impact of population-level features, classification algorithm and locally adaptive thresholding.

Neuroimage 2019 Jul 31;202:116056. Epub 2019 Jul 31.

Wellcome Centre for Integrative Neuroimaging, Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2019.116056DOI Listing
July 2019

Prognostic value of "tissue-based" definitions of TIA and minor stroke: Population-based study.

Neurology 2019 May 17;92(21):e2455-e2461. Epub 2019 Apr 17.

From the Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541432PMC
May 2019

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.

PLoS One 2018 1;13(11):e0206554. Epub 2018 Nov 1.

University of Maryland School of Medicine, Baltimore, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206554PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211695PMC
April 2019

Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study.

Lancet Neurol 2019 Mar 12;18(3):248-258. Epub 2019 Feb 12.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital and University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S1474-4422(18)30442-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390174PMC
March 2019

Disseminated leptomeningeal tumour mimicking a subarachnoid haemorrhage.

Neuroradiol J 2019 Feb 9;32(1):53-56. Epub 2018 Aug 9.

2 Nuffield Department of Clinical Neuroscience, University of Oxford, UK.

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http://dx.doi.org/10.1177/1971400918793530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327359PMC
February 2019

Genetic variation in is associated with white matter hyperintensities (n = 11,226).

Neurology 2019 02 18;92(8):e749-e757. Epub 2019 Jan 18.

From the Department of Clinical Neurosciences, Stroke Research Group (M.T., D.J.T., I.D.C., D.M.L.F., A.O.O., L.R.-J., H.S.M.), University of Cambridge, UK; Department of Cerebrovascular Diseases (G.B.), Fondazione IRCCS Istituto Neurologico "Carlo Besta," Milan, Italy; Institute for Stroke and Dementia Research (M.D.), Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich; German Center for Neurodegenerative Diseases (DZNE) and Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND) (R.L.), KU Leuven-University of Leuven; Department of Neurology (R.L.), University Hospitals Leuven; Laboratory of Neurobiology (R.L.), VIB Center for Brain and Disease Research, Leuven, Belgium; Center for Human Genetic Research (J.R.) and Division of Neurocritical Care and Emergency Neurology (J.R.) and J. Philip Kistler Stroke Research Center (J.R., N.S.R.), Department of Neurology, Massachusetts General Hospital, Boston; Nuffield Department of Clinical Neurosciences (Clinical Neurology), Stroke Prevention Research Unit (P.M.R.), University of Oxford; Centre for Clinical Brain Sciences and Institute for Genetics and Molecular Medicine (C.L.M.S.), University of Edinburgh, UK; Stroke Division, Florey Institute of Neuroscience and Mental Health (V.T.), University of Melbourne; and Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000006952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396967PMC
February 2019

Modelling the distribution of white matter hyperintensities due to ageing on MRI images using Bayesian inference.

Neuroimage 2019 01 22;185:434-445. Epub 2018 Oct 22.

Oxford Centre for Functional MRI of Brain (FMRIB), Wellcome Centre for Integrative NeuroImaging, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183201
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2018.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299259PMC
January 2019

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Authors:
Ganesh Chauhan Hieab H H Adams Claudia L Satizabal Joshua C Bis Alexander Teumer Muralidharan Sargurupremraj Edith Hofer Stella Trompet Saima Hilal Albert Vernon Smith Xueqiu Jian Rainer Malik Matthew Traylor Sara L Pulit Philippe Amouyel Bernard Mazoyer Yi-Cheng Zhu Sara Kaffashian Sabrina Schilling Gary W Beecham Thomas J Montine Gerard D Schellenberg Olafur Kjartansson Vilmundur Guðnason David S Knopman Michael E Griswold B Gwen Windham Rebecca F Gottesman Thomas H Mosley Reinhold Schmidt Yasaman Saba Helena Schmidt Fumihiko Takeuchi Shuhei Yamaguchi Toru Nabika Norihiro Kato Kumar B Rajan Neelum T Aggarwal Philip L De Jager Denis A Evans Bruce M Psaty Jerome I Rotter Kenneth Rice Oscar L Lopez Jiemin Liao Christopher Chen Ching-Yu Cheng Tien Y Wong Mohammad K Ikram Sven J van der Lee Najaf Amin Vincent Chouraki Anita L DeStefano Hugo J Aparicio Jose R Romero Pauline Maillard Charles DeCarli Joanna M Wardlaw Maria Del C Valdés Hernández Michelle Luciano David Liewald Ian J Deary John M Starr Mark E Bastin Susana Muñoz Maniega P Eline Slagboom Marian Beekman Joris Deelen Hae-Won Uh Robin Lemmens Henry Brodaty Margaret J Wright David Ames Giorgio B Boncoraglio Jemma C Hopewell Ashley H Beecham Susan H Blanton Clinton B Wright Ralph L Sacco Wei Wen Anbupalam Thalamuthu Nicola J Armstrong Elizabeth Chong Peter R Schofield John B Kwok Jeroen van der Grond David J Stott Ian Ford J Wouter Jukema Meike W Vernooij Albert Hofman André G Uitterlinden Aad van der Lugt Katharina Wittfeld Hans J Grabe Norbert Hosten Bettina von Sarnowski Uwe Völker Christopher Levi Jordi Jimenez-Conde Pankaj Sharma Cathie L M Sudlow Jonathan Rosand Daniel Woo John W Cole James F Meschia Agnieszka Slowik Vincent Thijs Arne Lindgren Olle Melander Raji P Grewal Tatjana Rundek Kathy Rexrode Peter M Rothwell Donna K Arnett Christina Jern Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Quenna Wong Braxton D Mitchell Stephen S Rich Patrick F McArdle Mirjam I Geerlings Yolanda van der Graaf Paul I W de Bakker Folkert W Asselbergs Velandai Srikanth Russell Thomson Rebekah McWhirter Chris Moran Michele Callisaya Thanh Phan Loes C A Rutten-Jacobs Steve Bevan Christophe Tzourio Karen A Mather Perminder S Sachdev Cornelia M van Duijn Bradford B Worrall Martin Dichgans Steven J Kittner Hugh S Markus Mohammad A Ikram Myriam Fornage Lenore J Launer Sudha Seshadri W T Longstreth Stéphanie Debette

Neurology 2019 Jan 16. Epub 2019 Jan 16.

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http://dx.doi.org/10.1212/WNL.0000000000006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369905PMC
January 2019

Late functional improvement after lacunar stroke: a population-based study.

J Neurol Neurosurg Psychiatry 2018 Dec 21;89(12):1301-1307. Epub 2018 Jul 21.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK

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http://dx.doi.org/10.1136/jnnp-2018-318434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288699PMC
December 2018

Ordinal vs dichotomous analyses of modified Rankin Scale, 5-year outcome, and cost of stroke.

Neurology 2018 11 19;91(21):e1951-e1960. Epub 2018 Oct 19.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000006554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260198PMC
November 2018

Time Trends in Atrial Fibrillation-Associated Stroke and Premorbid Anticoagulation.

Stroke 2018 Nov 29:STROKEAHA118022249. Epub 2018 Nov 29.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (G.S.C.Y., L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314508PMC
November 2018

Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke.

Int J Stroke 2018 10 3;13(8):832-839. Epub 2018 Jul 3.

1 Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/1747493018784448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424409PMC
October 2018

Long-Term Consequences of Worsened Poststroke Status in Patients With Premorbid Disability.

Stroke 2018 Oct;49(10):2430-2436

From the Nuffield Department of Clinical Neurosciences, Stroke Prevention Research Unit, University of Oxford, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022416
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.118.022416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159688PMC
October 2018

Long-Term Premorbid Blood Pressure and Cerebral Small Vessel Disease Burden on Imaging in Transient Ischemic Attack and Ischemic Stroke.

Stroke 2018 Sep;49(9):2053-2060

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.021578
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.118.021578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116796PMC
September 2018

Hospital and Institutionalisation Care Costs after Limb and Visceral Ischaemia Benchmarked Against Stroke: Long-Term Results of a Population Based Cohort Study.

Eur J Vasc Endovasc Surg 2018 08 11;56(2):271-281. Epub 2018 Apr 11.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejvs.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105571PMC
August 2018

Long-Term Prognosis of Patients With Transient Ischemic Attack or Stroke and Symptomatic Vascular Disease in Multiple Arterial Beds.

Stroke 2018 07 7;49(7):1639-1646. Epub 2018 Jun 7.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.118.020913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023586PMC
July 2018

Prevalence of patent foramen ovale in cryptogenic transient ischaemic attack and non-disabling stroke at older ages: a population-based study, systematic review, and meta-analysis.

Lancet Neurol 2018 07 7;17(7):609-617. Epub 2018 Jun 7.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S1474-4422(18)30167-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004554PMC
July 2018

Clinical innovation in stroke: getting the simple things right.

Authors:
Peter M Rothwell

Lancet Neurol 2018 06 10;17(6):491-493. Epub 2018 Apr 10.

Centre for Prevention of Stroke and Dementia, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30113-3DOI Listing
June 2018

Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review.

Stroke 2018 06 10;49(6):1434-1442. Epub 2018 May 10.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (K.K.L., C.E.L., L.L., M.S., S.G., W.K., P.M.R.)

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http://dx.doi.org/10.1161/STROKEAHA.117.020104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976229PMC
June 2018

Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke.

N Engl J Med 2018 Jun 16;378(23):2182-2190. Epub 2018 May 16.

From Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Neurology and Stroke Center (P.A., P.C.L., L.M.T., J.L., P.-J.T.), and the Department of Cardiology (P.G.S.), Bichat Hospital, INSERM Laboratory for Vascular Translational Science-Unité 1148, Département Hospitalo-Universitaire Fibrose Inflammation Remodelage, Université Paris-Diderot, Sorbonne-Paris Cité, and AP-HP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal Hospital (É.V.), Paris, and Université Lille, Centre Hospitalier Universitaire Lille, Équipe d'Accueil 2694-Santé Publique: Épidémiologie et Qualité des Soins, Lille (J.L.) - all in France; the Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, CA (G.W.A.); the Department of Neurology, Hôtel-Dieu de France, Saint Joseph University, Beirut, Lebanon (H. Abboud); the Stroke Unit, San Camillo Hospital, Rome (S.A.); Ärztliche Leitung der Klinik für Neurologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Berlin (H. Audebert), Klinik für Neurologie, Allgemeines Krankenhaus Celle, Celle (W.H.), and the Department of Neurology, Universitäts Medizin Mannheim, Heidelberg University, Heidelberg (M.G.H.) - all in Germany; Shaare Zedek Medical Center, Jerusalem, Israel (N.M.B.); the Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston (L.R.C.); Serviço de Neurologia, Hospital de Santo António-Centro Hospitalar do Porto, Porto (M.C.), and the Department of Neurosciences, Service of Neurology, Hospital Santa Maria, University of Lisbon, Lisbon (J.M.F.) - both in Portugal; the Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia (G.A.D.); the Stroke Unit and Neurology Service, University Hospital José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico (F.G.-R.); the Neurovascular Research Unit and Health Research Board, Stroke Clinical Trials Network Ireland, University College Dublin, Dublin (P.J.K.); the Comprehensive Stroke Center, Palacký University and University Hospital Olomouc (M.K.), and the Department of Nursing, Faculty of Health Science, Palacký University (D.Š), Olomouc, Czech Republic; the Department of Neurology, Kaohsiung Medical University Chung-Ho Memorial Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan (H.-F.L.); the Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona (C.M.), the Stroke Unit, Hospital Universitari Arnau de Vilanova, Universitat de Lleida, Lleida (F.P.), and the Stroke Unit, Department of Neurology, Albacete University Hospital, Universidad de Castilla-La Mancha, Albacete (T.S.) - all in Spain; the Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, South Korea (J.M.P.); the Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford (P.M.R.), and the National Heart and Lung Institute Imperial College, Institute of Cardiovascular Medicine and Science Royal Brompton Hospital, London (P.G.S.) - both in the United Kingdom; the International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo (S.U.); the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing (Y.W.); and the Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (L.K.S.W.).

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http://dx.doi.org/10.1056/NEJMoa1802712DOI Listing
June 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Time course of blood pressure control prior to lacunar TIA and stroke: Population-based study.

Neurology 2018 05 18;90(20):e1732-e1741. Epub 2018 Apr 18.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neuroscience University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957302PMC
May 2018

Factors contributing to sex differences in functional outcomes and participation after stroke.

Neurology 2018 05 27;90(22):e1945-e1953. Epub 2018 Apr 27.

From the Menzies Institute for Medical Research Tasmania (H.T.P., C.L.B., P.O., S.L.G.), University of Tasmania, Hobart, Australia; Department of Health Management and Health Economics (H.T.P.), Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam; Department of Epidemiology and Biostatistics (M.J.R.), Michigan State University, East Lansing; Department of Medicine (A.G.T., D.A.C.), School of Clinical Sciences at Monash Health, Monash University, Clayton; Florey Institute Neuroscience and Mental Health (D.A.C.), Heidelberg, University of Melbourne, Victoria; Faculty of Health and Medicine (J.S.), University of Newcastle; George Institute for Global Health (E.H., C.A.), University of Sydney, New South Wales, Australia; Hellenic Cardiovascular Research Society (K.V.), Athens, Greece; National Institute for Stroke and Applied Neurosciences (P.P., R.K., V.F.), School of Public Health and Psychosocial Studies, Auckland University of Technology; School of Psychology (S.B.-C.), University of Auckland, New Zealand; University of Burgundy (Y.B.), University Hospital of Dijon, France; Clinica Neurológica de Joinville (N.L.C.), Joinville Stroke Registry, University of Joinville Region, Brazil; Department of Biotechnological and Applied Clinical Sciences (A.C., S.S.), Neurological Institute, University of L'Aquila, Italy; Stroke Unit (N.C.), Centre Hospitalier Sud Francilien, Corbeil-Essonnes; Stroke Unit (S.O.), University Hospital of Bordeaux, France; Stroke Prevention Research Unit (P.R.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK; UNIFAI (C.S., M.C., R.M.), Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Portugal; Department of Neurology (P.A.), Faculty of Medicine and Health, Örebro University, Sweden; Department of Neurology and Neurosurgery (J.K., R.V.), University of Tartu, Estonia; and Hospital Carlos Fernando Malzoni and Neurologic Center of Research and Rehabilitation (C.M.), Matão, SP, Brazil.

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http://dx.doi.org/10.1212/WNL.0000000000005602DOI Listing
May 2018

Age-Specific Associations of Renal Impairment With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Transient Ischemic Attack and Stroke.

Stroke 2018 04 9;49(4):899-904. Epub 2018 Mar 9.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences University of Oxford, United Kingdom (B.L., K.K.L., L.L., C.L., W.K., P.M.R.); and Department of Neurology, Cerebrovascular Centre, West China Hospital, Sichuan University (B.L., M.L.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895118PMC
April 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-018-0058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

External Validation of Risk Scores for Major Bleeding in a Population-Based Cohort of Transient Ischemic Attack and Ischemic Stroke Patients.

Stroke 2018 03 19;49(3):601-606. Epub 2018 Feb 19.

From the Julius Center for Health Sciences and Primary Care (N.A.H., A.A., J.P.G.) and Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (A.A.), University Medical Center Utrecht, Utrecht University, the Netherlands; and Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839707PMC
March 2018

Early time course of major bleeding on antiplatelet therapy after TIA or ischemic stroke.

Neurology 2018 02 26;90(8):e683-e689. Epub 2018 Jan 26.

From the Julius Center for Health Sciences and Primary Care (N.A.H., A.A., J.P.G.) and Department of Neurology and Neurosurgery (A.A., L.J.K.), Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, the Netherlands; Stroke Trials Unit (P.M.B.), Division of Clinical Neuroscience, University of Nottingham, UK; Department of Neurology (L.C.), University of Debrecen Medical and Health Science Center, Hungary; and Stroke Prevention Research Unit (P.M.R.), Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818163PMC
February 2018

Time-of-Day Could Affect Cognitive Screening Performance in Older Patients with TIA and Stroke.

Cerebrovasc Dis 2017 21;43(5-6):290-293. Epub 2017 Mar 21.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1159/000456673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475237PMC
January 2018

Prognostic Significance of Blood Pressure Variability on Beat-to-Beat Monitoring After Transient Ischemic Attack and Stroke.

Stroke 2018 01 11;49(1):62-67. Epub 2017 Dec 11.

From the Department of Clinical Neurosciences, Centre for Prevention of Stroke and Dementia, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.117.019107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742536PMC
January 2018

Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack.

Stroke 2018 01 15;49(1):54-61. Epub 2017 Dec 15.

From the Stroke Research Group, Clinical Neurosciences, University of Cambridge, United Kingdom (R.L.B., H.S.M.); Division of Health and Social Care Research, Faculty of Life Sciences and Medicine, King's College London, United Kingdom (S.C., C.D.A.W.); National Epidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario (Q.Y.); School of Medicine and Pharmacology, The University of Western Australia, Perth (G.J.H.); Department of Neurology, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Western Australian Neuroscience Research Institute, Perth (G.J.H.); and Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753817PMC
January 2018

Antiplatelet cessation to manage bleeding events in elderly people - Authors' reply.

Lancet 2017 12 8;390(10112):2548. Epub 2017 Dec 8.

Centre for Prevention of Stroke and Dementia, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)33087-8DOI Listing
December 2017

Confounding by Pre-Morbid Functional Status in Studies of Apparent Sex Differences in Severity and Outcome of Stroke.

Stroke 2017 10 10;48(10):2731-2738. Epub 2017 Aug 10.

From the Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada (C.R., J.C.); Departments of Neurology and Neurosurgery (C.R.) and Epidemiology and Biostatistics (C.R.), McGill University, Montréal, Québec, Canada; and Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, United Kingdom (C.R., L.L., A.G., L.S., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610564PMC
October 2017

Global stroke statistics: An update of mortality data from countries using a broad code of "cerebrovascular diseases".

Int J Stroke 2017 10 12;12(8):796-801. Epub 2017 Sep 12.

2 Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, USA.

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http://dx.doi.org/10.1177/1747493017730782DOI Listing
October 2017

Stenting for symptomatic vertebral artery stenosis: The Vertebral Artery Ischaemia Stenting Trial.

Neurology 2017 Sep 23;89(12):1229-1236. Epub 2017 Aug 23.

From the Stroke Research Group (H.S.M., S.C.L.), Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus; Nuffield Department of Clinical Neurosciences (W.K., U.G.S., P.M.R.), John Radcliffe Hospital, University of Oxford; Robertson Centre for Biostatistics (I.F.), University of Glasgow; and Department of Neuroradiology (A.C.), St. George's Hospital, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606920PMC
September 2017

Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation.

Stroke 2017 08 23;48(8):2292-2296. Epub 2017 May 23.

From the Acute Stroke Programme, Radcliffe Department of Medicine, John Radcliffe Hospital (Y.C., A.A.N., A.M.B.), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital (N.A.), Target Discovery Institute, Nuffield Department of Medicine (S.D., R.F.), and Centre for Prevention of Stroke and Dementia, John Radcliffe Hospital, Nuffield Department of Clinical Neurosciences (P.M.R., A.I.B.), University of Oxford, United Kingdom; and Turku Centre for Biotechnology, University of Turku, Biocity, Finland (A.M.D.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531255PMC
August 2017

Prognostic Value of Variability in Systolic Blood Pressure Related to Vascular Events and Premature Death in Type 2 Diabetes Mellitus: The ADVANCE-ON Study.

Hypertension 2017 08 5;70(2):461-468. Epub 2017 Jun 5.

From the George Institute for Global Health (T.O., M.W., M.J., J.H., J.C.), and Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, Sydney Medical School (S.C.), University of Sydney, New South Wales, Australia; The George Institute for Global Health, University of Oxford, United Kingdom (M.W.); Department of Epidemiology, Johns Hopkins University, Baltimore, MD (M.W.); Departments of Epidemiology (P.M.) and Medicine (P.M.), University of Alabama at Birmingham; Department of Physiology, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia (S.H.); University of Milan-Bicocca and Instituto Auxologico Italiano (G.M.); International Centre for Circulatory Health, Imperial College, London, UK (N.P.); Institute of Cardiovascular Sciences, University College London (UCL) and National Institute of Health Research UCL Hospitals Biomedical Research Centre, London, UK (B.W.); and Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (P.R.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09359DOI Listing
August 2017

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org.

Stroke 2017 07 5;48(7):1779-1787. Epub 2017 Jun 5.

From the APHP, Department of Neurology and Stroke Center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, France (T.H., L.S., P.C.L., P-J.T., P.A.); Clinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo, Japan (S.U.); Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital (L.K.S.W.); Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center, CA (G.W.A.); Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Israel (N.M.B.); Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA (L.R.C.); The Florey Institute of Neuroscience and Mental Health, the University of Melbourne, Parkville, VIC, Australia (G.A.D.); Department of Neurosciences, Hospital Santa Maria, University of Lisbon, Portugal (J.M.F.); Department of Neurology, Universitäts Medizin Mannheim, Heidelberg, Germany (M.G.H.); Université de Lille, CHU Lille, EA 2694-Santé publique: épidémiologie et qualité des soins, France (J.L.); Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Universitat Autonoma de Barcelona, Spain (C.M.); Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, United Kingdom (P.M.R.); APHP, Department of Cardiology, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, Hôpital Bichat, France, and NHLI Imperial College, ICMS Royal Brompton Hospital, London, United Kingdom (P.G.S.); APHP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal Hospital, France (É.V.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016874DOI Listing
July 2017

Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study.

Lancet 2017 07 13;390(10093):490-499. Epub 2017 Jun 13.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30770-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537194PMC
July 2017

Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms.

Stroke 2017 06 3;48(6):1451-1456. Epub 2017 May 3.

From the Stroke Research Center (C.D.A., J.R.), Center for Human Genetic Research (C.D.A., J.R.), and Cardiovascular Research Center (S.A.L., L.-C.W., P.T.E.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, The Broad Insitute of Harvard and MIT, Cambridge, MA (S.A.L., L.-C.W., C.D.A., J.R., P.T.E.); Autism Research Centre (O.E.P.) and Department of Clinical Neurosciences (H.S.M., M.T.), University of Cambridge, United Kingdom; Boston University and National Heart, Lung and Blood Institute's Framingham Heart Study, MA (E.J.B.); Section of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, MA (E.J.B.); Department of Epidemiology, Boston University School of Public Health, MA (E.J.B.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians Universität, Germany (R.M., M.D.); Munich Cluster of Systems Neurology (SyNergy), Germany (M.D.); Division of Clinical Neurosciences, Neuroimaging Sciences and Institute of Genetics and Molecular Medicine, University of Edinburgh, United Kingdom (C.L.S.); and Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, United Kingdom (P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.116.016198DOI Listing
June 2017

White Matter Imaging Correlates of Early Cognitive Impairment Detected by the Montreal Cognitive Assessment After Transient Ischemic Attack and Minor Stroke.

Stroke 2017 06 9;48(6):1539-1547. Epub 2017 May 9.

From the Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital (G.Z., L.G., S.M., L.L., W.K., S.T.P., P.M.R.) and Oxford Centre for Functional MRI of the Brain (FMRIB) (M.J.), Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.116.016044DOI Listing
June 2017

Clinical Correlates, Ethnic Differences, and Prognostic Implications of Perivascular Spaces in Transient Ischemic Attack and Ischemic Stroke.

Stroke 2017 06 11;48(6):1470-1477. Epub 2017 May 11.

From the Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (K.-K.L., L.L., C.E.L., G.Z., W.K., P.M.R.); Epsom and St Helier University Hospitals, NHS Trust, Carshalton, United Kingdom (C.E.L.); and Division of Neurology, Department of Medicine (K.-K.L., T.-T.C., M.-F.C., K.-T.L.) and Department of Diagnostic Radiology (H.K.-F.M.), Li Ka Shing Faculty of Medicine, University of Hong Kong.

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http://dx.doi.org/10.1161/STROKEAHA.117.016694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436733PMC
June 2017

Total small vessel disease score and risk of recurrent stroke: Validation in 2 large cohorts.

Neurology 2017 Jun 17;88(24):2260-2267. Epub 2017 May 17.

From the Centre for Prevention of Stroke and Dementia (K.K.L., L.L., U.S., M.S., W.K., P.M.R.), Nuffield Department of Clinical Neurosciences, University of Oxford, UK; and Division of Neurology, Department of Medicine (K.K.L., K.H.C., S.L.H., R.T.F.C.), and Department of Diagnostic Radiology (H.K.F.M.), Li Ka Shing Faculty of Medicine, University of Hong Kong.

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http://dx.doi.org/10.1212/WNL.0000000000004042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567324PMC
June 2017

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting.

Stroke 2017 04 13;48(4):1005-1010. Epub 2017 Mar 13.

From APHP, Department of Neurology and Stroke Center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, France (C.H., P.C.L., L.S., J.L., P.-J.T., P.A.); Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center (G.W.A.); Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Israel (N.M.B.); Department of Neurosciences (Neurology), Hospital Santa Maria, University of Lisbon, Portugal (J.M.F.); Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA (L.R.C.); The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia (G.A.D.); Department of Neurology, UMM University Heidelberg, Germany (M.G.H.); Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Universitat Autonoma de Barcelona, Spain (C.M.); Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, UK (P.M.R.); APHP, Department of Cardiology, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, Hôpital Bichat, Paris, France; and NHLI Imperial College, ICMS Royal Brompton Hospital London, UK (P.G.S.); Clinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo, Japan (S.U.); APHP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal hospital, Paris, France (É.V.); and Department of Medicine & Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR (K.S.L.W.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015171DOI Listing
April 2017

Sex Differences in Long-Term Mortality After Stroke in the INSTRUCT (INternational STRoke oUtComes sTudy): A Meta-Analysis of Individual Participant Data.

Circ Cardiovasc Qual Outcomes 2017 02 22;10(2). Epub 2017 Feb 22.

From the Menzies Institute for Medical Research Tasmania, University of Tasmania, Hobart, Australia (H.T.P., C.L.B., P.O., S.G.); Department of Health Management and Health Economics, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam (H.T.P.); Department of Epidemiology and Biostatistics, Michigan State University, East Lansing (M.J.R.); Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia (A.G.T., D.C.); Florey Institute Neuroscience and Mental Health, Heidelberg, University of Melbourne, Victoria, Australia (D.C.); Faculty of Health and Medicine, University of Newcastle, New South Wales, Australia (J.S.); George Institute for Global Health, University of Sydney, New South Wales, Australia (E.H., C.A.); Hellenic Cardiovascular Research Society, Athens, Greece (V.K.); National Institute for Stroke and Applied Neurosciences, School of Public Health and Psychosocial Studies, Auckland, New Zealand (P.P., R.K., V.F.); School of Psychology, University of Auckland, New Zealand (S.B.-C.); University of Burgundy, Dijon, France (Y.B.); University Hospital of Dijon, France (Y.B.); Clinica Neurológica de Joinville, Joinville Stroke Registry, University of Joinville Region-Univille, Brazil (N.L.C.); Department of Biotechnological and Applied Clinical Sciences, Neurological Institute, University of L'Aquila, Italy (A.C., S.S.); Stroke Unit, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France (N.C.); Stroke Unit, University Hospital of Bordeaux, France (S.O.); Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom (P.R.); UNIFAI, Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Portugal (C.S., M.C., R.M.); Department of Neurology, Faculty of Medicine and Health, Örebro University, Sweden (P.A.); Department of Neurology and Neurosurgery, University of Tartu, Estonia (J.K., R.V.); and Departamento de Neurologia, Psicologia e Psiquiatria, Universidade de São Paulo, Ribeirão Preto, Brazil (C.M.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.116.003436DOI Listing
February 2017

Global stroke statistics.

Int J Stroke 2017 01 28;12(1):13-32. Epub 2016 Oct 28.

1 Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.

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http://dx.doi.org/10.1177/1747493016676285DOI Listing
January 2017

Stroke research in 2016: when more medicine is better, and when it isn't.

Authors:
Peter M Rothwell

Lancet Neurol 2017 01;16(1):2-3

Centre for Prevention of Stroke and Dementia, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)30332-5DOI Listing
January 2017

Molecular magnetic resonance imaging discloses endothelial activation after transient ischaemic attack.

Brain 2017 01 8;140(1):146-157. Epub 2016 Nov 8.

1 Normandie Univ, UNICAEN, INSERM U919, Serine Proteases and Pathophysiology of the Neurovascular Unit, Cyceron, 14000 Caen, France

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http://dx.doi.org/10.1093/brain/aww260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226059PMC
January 2017

Risk and treatment effect heterogeneity: re-analysis of individual participant data from 32 large clinical trials.

Int J Epidemiol 2016 12;45(6):2075-2088

Department of Internal Medicine and Department of Health Management and Policy, University of Michigan, Ann Arbor, MI, USA.

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http://ije.oxfordjournals.org/content/early/2016/07/02/ije.d
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http://dx.doi.org/10.1093/ije/dyw118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841614PMC
December 2016

Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack: a pooled analysis of individual-patient data from cohort studies.

Lancet Neurol 2016 Nov 11;15(12):1238-1247. Epub 2016 Oct 11.

Neurovascular Clinical Science Unit, Stroke Service and Department of Neurology, Mater University Hospital/University College Dublin, Dublin Academic Medical Centre, Dublin, Ireland; Chelsea and Westminster NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(16)30236-8DOI Listing
November 2016

Brain Atrophy, N-Terminal Brain Natriuretic Peptide, and Carotid Disease: Interconnecting Relationships Between Cerebral Perfusion, Cardiovascular Disease, Inflammation, and Cognitive Decline.

Arterioscler Thromb Vasc Biol 2016 11;36(11):2141-2142

From the Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences (S.T.P., P.M.R.) and NIHR Oxford Biomedical Research Centre (S.T.P., P.M.R.), John Radcliffe Hospital, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/ATVBAHA.116.308362DOI Listing
November 2016

Recurrent stroke risk and cerebral microbleed burden in ischemic stroke and TIA: A meta-analysis.

Neurology 2016 Oct 2;87(14):1501-1510. Epub 2016 Sep 2.

From the Stroke Research Centre (D.W., A.C., S.G., P.R., D.J.W.), Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery; Department of Statistical Science (G.A.) and Biomedical Research Centre (Z.V.F.), UCL, London, UK; Department of Neurosurgery (T.I.), Kushiro City General Hospital, Hokkaido, Japan; Department of Neurology (F.F.), University Hospital Würzburg, Germany; Department of Neurology (H.N.), Suiseikai Kajikawa Hospital, Hiroshima, Japan; Department of Neurology (S.H.), University of Heidelberg, Germany; Department of Stroke Medicine (R.V.), Division of Brain Sciences, Imperial College London; Nuffield Department of Clinical Neurosciences (P.M.R.), John Radcliffe Hospital, University of Oxford, UK; Department of Neurology (V.I.H.K.), Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; Department of Neurology (V.T.), Austin Health and Melbourne Brain Center, University of Melbourne, Australia; Department of Neurology (Y.-S.L.), Seoul National University Boramae Medical Center; Department of Neurology (Y.D.K.), Yonsei University College of Medicine, Seoul, Korea; Department of Neurology (Y.H.), Peking University First Hospital, Beijing, China; Division of Neurology (K.S.W.), Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and Lysholm Department of Neuroradiology (H.R.J.), National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000003183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075978PMC
October 2016

A comparison between the MoCA and the MMSE visuoexecutive sub-tests in detecting abnormalities in TIA/stroke patients.

Int J Stroke 2016 06 10;11(4):420-4. Epub 2016 Feb 10.

Stroke Prevention Research Unit, Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK Oxford NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1177/1747493016632238DOI Listing
June 2016

Cost-utility analysis of stenting versus endarterectomy in the International Carotid Stenting Study.

Int J Stroke 2016 06 15;11(4):446-53. Epub 2016 Feb 15.

Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1177/1747493016632237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341766PMC
June 2016

Magnetic Resonance Imaging Measurement of Transmission of Arterial Pulsation to the Brain on Propranolol Versus Amlodipine.

Stroke 2016 06 3;47(6):1669-72. Epub 2016 May 3.

From the Stroke Prevention Research Unit (SPRU), John Radcliffe Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.115.012411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328287PMC
June 2016

Blood Pressure and Risk of Vascular Dementia: Evidence From a Primary Care Registry and a Cohort Study of Transient Ischemic Attack and Stroke.

Stroke 2016 06 10;47(6):1429-35. Epub 2016 May 10.

From the George Institute for Global Health (C.A.E., G.S.-K., A.K., N.C., T.C., S.G.A., H.M., M.W., K.R.), Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences (P.M.R., Z.M., S.T.P.), and Division of Cardiovascular Medicine, Radcliffe Department of Medicine (K.R.), University of Oxford, United Kingdom; The George Institute for Global Health, University of Sydney, Australia (M.W.); and Department of Epidemiology, Johns Hopkins University, Baltimore, MD (M.W.).

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http://dx.doi.org/10.1161/STROKEAHA.116.012658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341765PMC
June 2016

Genetic Associations With White Matter Hyperintensities Confer Risk of Lacunar Stroke.

Stroke 2016 05 12;47(5):1174-9. Epub 2016 Apr 12.

From the Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (M.T., L.C.A.R.-J., H.S.M.); Department of Medical and Molecular Genetics, King's College London, London, United Kingdom (M.T.); Laboratory of Neurobiology, Vesalius Research Center, VIB, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, University of Leuven, Leuven, Belgium (V.T.); Department of Neurology, Austin Health and Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia (V.T.); School of Medicine and Public Health (E.G.H.) and Centre for Clinical Epidemiology and Biostatistics, Hunter Medical Research Institute and School of Medicine and Public Health (C.L.), University of Newcastle, Newcastle, NSW, Australia; Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia (E.G.H.); School of Life Science, University of Lincoln, Lincoln, United Kingdom (S.B.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany (R.M., M.D.); Department of Cerebrovascular Disease, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (G.B.); Division of Clinical Neurosciences, Neuroimaging Sciences and Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom (C.S.); Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, Oxford, United Kingdom (P.M.R.); and Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (M.D.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839546PMC
May 2016

Biases in detection of apparent "weekend effect" on outcome with administrative coding data: population based study of stroke.

BMJ 2016 May 16;353:i2648. Epub 2016 May 16.

Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868367PMC
http://dx.doi.org/10.1136/bmj.i2648DOI Listing
May 2016

Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke.

Stroke 2016 Apr 15;47(4):1045-52. Epub 2016 Mar 15.

From the Université Paris Diderot, Paris, France (J.G.-V., M.-G.B., P.G.S., E.V., P.A.); INSERM LVTS (Laboratory for VascularTranslational Sciences) 1148 and Département Hospitalo-Universitaire FIRE (Fibrosis, Inflammation, Remodelling), Paris, France (L.S., J.L., P.G.S., P.A.); Department of Neurology and Stroke Centre, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris France (J.G.-V., L.S., J.L., P.A.); Université de Lille, CHU Lille, EA 2694-Santé publique: épidémiologie et qualité des soins, Lille, France (J.L.); Department of Neurology, hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France (M.-G.B.); Department of Neurology, Hospital Clinic de Barcelona, University of Barcelona, Barcelona, Spain (A.C.); Department of Neurology, Harvard University, Brigham and Women Hospital, MA (M.F.); Robertson Centre for Biostatistics, Department of Biostatistics, University of Glasgow, Glasgow, UK (I.F.); Department of Cardiology, NHLI Imperial College, ICMS, Royal Brompton Hospital, London, UK (K.M.F.; P.G.S.); Department of Neurology, University of Heidelberg, UMM, Mannheim, Germany (M.G.H.); Neurologische Klinik und Poliklinik, Universität Bern, Inselspital, Bern (H.P.M.); Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK (P.M.R.); and Department of Biostatistics, Hôpital Fernand Widal, Assistance Publique-Hôpitaux de Paris, Paris France (E.V.).

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http://dx.doi.org/10.1161/STROKEAHA.115.012091DOI Listing
April 2016

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke.

N Engl J Med 2016 Apr;374(16):1533-42

From the Departments of Neurology (P.A., P.C.L., J.L., L.S., P.-J.T.) and Cardiology (P.G.S.) and the Stroke Center (P.A., P.C.L., J.L., L.S., P.-J.T.), Assistance Publique-Hôpitaux de Paris (AP-HP), Bichat Hospital, and the Department of Biostatistics, AP-HP Fernand Widal Hospital (E.V.), Université Paris-Diderot, Sorbonne-Paris Cité, Paris, and Université Lille, Centre Hospitalier Universitaire Lille, Santé Publique, Epidémiologie et Qualité des Soins, Lille (J.L.) - all in France; the Department of Neurology and Neurological Sciences, Stanford Stroke Center, Stanford University Medical Center, Stanford, CA (G.W.A.); the Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel (N.M.B.); the Department of Neurosciences, Hospital Santa Maria, University of Lisbon, Lisbon, Portugal (P.C., J.M.F.); the Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston (L.R.C.); the Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia (G.A.D.); the Department of Neurology, Universitäts Medizin Mannheim, Heidelberg University, Heidelberg, Germany (M.G.H.); the Department of Neurology, Stroke Unit, Vall d'Hebron University Hospital, Universitat Autonoma de Barcelona, Barcelona (C.M.); the Nuffield Department of Clinical Neuroscience, Stroke Prevention Research Unit, University of Oxford, Oxford (P.M.R.), and the National Heart and Lung Institute Imperial College, Institute of Cardiovascular Medicine and Science, Royal Brompton Hospital, London (P.G.S.) - both in the United Kingdom; the Department of Nursing, Palacky University, Olomouc, Czech Republic (D.S.); Clinical Research Center, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo (S.U.); and the Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong K

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http://dx.doi.org/10.1056/NEJMoa1412981DOI Listing
April 2016

Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.

Stroke 2016 Mar 2;47(3):646-51. Epub 2016 Feb 2.

From the Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK (L.C.A.R.-J., M.T., H.S.M.); Department of Medical & Molecular Genetics, King's College London, London, UK (M.T.); Stroke and Dementia Research Centre, Department of Clinical Neuroscience, St George's University of London, London, UK (P.A.-S.); KULeuven Department of Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, University of Leuven, and Laboratory of Neurobiology, Vesalius Research Center, VIB, Leuven, Belgium and Department of Neurology, Austin Health and Florey Institute of Neuroscience and Mental Health, Heidelberg, Australia (V.T.); Division of Clinical Neurosciences, Neuroimaging Sciences and Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK (C.S.); Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, UK (P.M.R.); Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico "Carlo Besta", Milano, Italy (G.B.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University Munich and Munich Cluster of Systems Neurology, SyNergy, Munich, Germany (M.D.); Department of Neurology, Mayo Clinic, Jacksonville (J.M.); School of Nursing and Midwifery (J.M.) and Hunter Medical Research Institute (J.M., C.L.), University of Newcastle, NSW, Australia; Center for Human Genetic Research and Department of Neurology, Massachusetts General Hospital, Boston (N.S.R., J.R.); Department of Neurology, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK (A.H.); and School of Life Science, University of Lincoln, Lincoln, UK (S.B.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760380PMC
March 2016

Stroke risk with symptomatic carotid stenosis: The future is not what it used to be.

Neurology 2016 Feb 8;86(6):494-5. Epub 2016 Jan 8.

From the Stroke Program and Department of Neurology (S.C.), University of Miami Miller School of Medicine, FL; and Nuffield Department of Clinical Neurosciences (P.M.R.), John Radcliffe Hospital, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000002363DOI Listing
February 2016

Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores.

Age Ageing 2016 Jan;45(1):60-5

NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital and the University of Oxford, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1093/ageing/afv177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711661PMC
January 2016