Peter R Durie

Peter R Durie

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Peter R Durie

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Therapeutic Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients With Acute Recurrent and Chronic Pancreatitis: Data From the INSPPIRE (INternational Study group of Pediatric Pancreatitis: In search for a cuRE) Study.

Pancreas 2017 07;46(6):764-769

From the *Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX; and †Section of Pediatric Gastroenterology and Nutrition, Baylor College of Medicine, Houston, TX; ‡Department of Pediatrics, Seattle Children's Hospital, Seattle, WA; §Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ∥Department of Medicine and Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA; ¶Department of Pediatrics, University of Minnesota, University of Minnesota Masonic Children's Hospital, Minneapolis, MN; #Department of Paediatrics, University of Toronto, and Research Institute, The Hospital for Sick Children, Toronto, Canada; **Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA; ††Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, OH; ‡‡Department of Pediatrics, University of California at San Francisco, San Francisco, CA; §§Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; ∥∥Department of Pediatrics, Rady Children's Hospital, San Diego, CA; ¶¶Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Canada; ##Faculty of Medicine, School of Women's and Children's Health, University of New South Wales and Sydney Children's Hospital Randwick, Sydney, Australia; ***Division of Pediatric Gastroenterology, University of Utah, Salt Lake City, UT; †††Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI; ‡‡‡Department of Pediatric Gastroenterology, Hadassah Hebrew University Hospital, Jerusalem, Israel; and §§§Department of Biostatistics, University of Iowa College of Public Health; and ∥∥∥Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA.

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http://dx.doi.org/10.1097/MPA.0000000000000848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502745PMC
July 2017

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

Features of Severe Liver Disease With Portal Hypertension in Patients With Cystic Fibrosis.

Clin Gastroenterol Hepatol 2016 08 5;14(8):1207-1215.e3. Epub 2016 Apr 5.

Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Canada; Department of Pediatrics, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.cgh.2016.03.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955685PMC
August 2016

Direct Costs of Acute Recurrent and Chronic Pancreatitis in Children in the INSPPIRE Registry.

J Pediatr Gastroenterol Nutr 2016 Mar;62(3):443-9

*University of California, San Francisco †University of Minnesota Masonic Children's Hospital, Minneapolis ‡Baylor College of Medicine, Houston, TX §University of Texas Southwestern Medical School, Dallas ||Hospital for Sick Children, Toronto, ON, Canada ¶Harvard Medical School, Boston, MA #Nationwide Children's Hospital, Columbus, OH **Seattle Children's Hospital, Seattle, WA ††Children's Hospital of Pittsburgh, Pittsburgh, PA ‡‡Montreal Children's Hospital, McGill University, Montreal, QC, Canada §§Discipline of Paediatrics, School of Women's and Children's Health, Medicine, University of New South Wales and Sydney Children's Hospital Randwick, Sydney, Australia ||||University of Utah, Salt Lake City, UT ¶¶Medical College of Wisconsin, Milwaukee, WI ##Hadassah Hebrew University Hospital, Jerusalem, Israel ***University of Iowa Carver College of Medicine, IA.

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http://dx.doi.org/10.1097/MPG.0000000000001057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767646PMC
March 2016

Cystic fibrosis from the gastroenterologist's perspective.

Nat Rev Gastroenterol Hepatol 2016 Mar 21;13(3):175-85. Epub 2016 Jan 21.

Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children 555 University Avenue Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1038/nrgastro.2015.226DOI Listing
March 2016

Altered intestinal bile salt biotransformation in a cystic fibrosis (Cftr-/-) mouse model with hepato-biliary pathology.

J Cyst Fibros 2015 Jul 27;14(4):440-6. Epub 2015 Jan 27.

Pediatric Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jcf.2014.12.010DOI Listing
July 2015

A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways.

Am J Hum Genet 2015 Jul;97(1):125-38

Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada; Department of Statistical Sciences, University of Toronto, Toronto, ON M5S 3G3, Canada. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(15)00201-3.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971500201
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http://dx.doi.org/10.1016/j.ajhg.2015.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572492PMC
July 2015

Inconclusive diagnosis of cystic fibrosis after newborn screening.

Pediatrics 2015 Jun 11;135(6):e1377-85. Epub 2015 May 11.

Division of Gastroenterology, Hepatology, and Nutrition, Physiology and Experimental Medicine, Research Institute,

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http://dx.doi.org/10.1542/peds.2014-2081DOI Listing
June 2015

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency.

PLoS Genet 2015 Jun 9;11(6):e1005288. Epub 2015 Jun 9.

Program in Genetics & Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1005288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461263PMC
June 2015

Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis.

J Pediatr 2015 May 11;166(5):1152-1157.e6. Epub 2015 Mar 11.

Program in Genetics and Genome Biology, the Hospital for Sick Children, Toronto, Ontario, Canada; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2015.01.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530786PMC
May 2015

Design and implementation of INSPPIRE.

J Pediatr Gastroenterol Nutr 2014 Sep;59(3):360-4

*Montreal Children's Hospital, McGill University, Montreal, Canada †Children's Hospital of Pittsburgh, Pittsburgh, PA ‡University of Iowa Children's Hospital (UICH), Iowa City §University of Texas Southwestern Medical School, Dallas ||University of Minnesota, Amplatz Children's Hospital, Minneapolis ¶The Hospital for Sick Children and University of Toronto, Toronto, Canada #Baylor College of Medicine, Houston, TX **Beth Israel Deaconess Medical Center, Boston, MA ††Nationwide Children's Hospital (NCH), Columbus, OH ‡‡Seattle Children's Hospital, Seattle, WA §§University of California at San Francisco ||||University of New South Wales and Sydney Children's Hospital, Randwick, Australia ¶¶University of Utah, Salt Lake City ##Hadassah Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1097/MPG.0000000000000417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141003PMC
September 2014

Evidence for a causal relationship between early exocrine pancreatic disease and cystic fibrosis-related diabetes: a Mendelian randomization study.

Diabetes 2014 Jun 18;63(6):2114-9. Epub 2014 Feb 18.

Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, CanadaDivision of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.2337/db13-1464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030111PMC
June 2014

Abdominal pain in adults with cystic fibrosis.

Eur J Gastroenterol Hepatol 2014 Feb;26(2):129-36

aWest Midlands Adult Cystic Fibrosis Centre, Heart of England NHS Foundation Trust, Birmingham bLeicester Adult Cystic Fibrosis Centre, Glenfield Hospital, Leicester, UK cToronto Adult CF Clinic, St Michael's Hospital dDepartment of Pediatrics, The Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MEG.0000000000000011DOI Listing
February 2014

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://petercroucher.com/wp-content/uploads/2013/10/51_Natur
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http://www.nature.com/doifinder/10.1038/ng.2616
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http://dx.doi.org/10.1038/ng.2616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

Role of cystic fibrosis transmembrane conductance regulator in patients with chronic sinopulmonary disease.

Chest 2012 Oct;142(4):996-1004

Department of Medicine, University of Toronto, Toronto, ON, Canada; Division of Respirology and Keenan Research Centre of Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S001236921260570
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http://dx.doi.org/10.1378/chest.11-2543DOI Listing
October 2012

Definitions of pediatric pancreatitis and survey of present clinical practices.

J Pediatr Gastroenterol Nutr 2012 Sep;55(3):261-5

Division of Pediatric Gastroenterology and Nutrition, Montreal Children's Hospital, McGill University, Canada.

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http://dx.doi.org/10.1097/MPG.0b013e31824f1516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626452PMC
September 2012

Variation in MSRA modifies risk of neonatal intestinal obstruction in cystic fibrosis.

PLoS Genet 2012 15;8(3):e1002580. Epub 2012 Mar 15.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1371/journal.pgen.1002580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305406PMC
September 2012

Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in pancreatitis.

J Cyst Fibros 2012 Sep 2;11(5):355-62. Epub 2012 Jun 2.

School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1016/j.jcf.2012.05.001DOI Listing
September 2012

Deficiency of Sbds in the mouse pancreas leads to features of Shwachman-Diamond syndrome, with loss of zymogen granules.

Gastroenterology 2012 Aug 14;143(2):481-92. Epub 2012 Apr 14.

Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2012.04.012DOI Listing
August 2012

Comparing the American and European diagnostic guidelines for cystic fibrosis: same disease, different language?

Thorax 2012 Jul 15;67(7):618-24. Epub 2012 Apr 15.

School of Women's and Children's Health, Faculty of Medicine, University of New South Wales and Sydney Children's Hospital, Randwick, Sydney, Australia.

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http://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2011-2014
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http://dx.doi.org/10.1136/thoraxjnl-2011-201454DOI Listing
July 2012

Ursodeoxycholic acid in cystic fibrosis-associated liver disease.

J Cyst Fibros 2012 Jan 23;11(1):72-3; author reply 74-75. Epub 2011 Aug 23.

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http://dx.doi.org/10.1016/j.jcf.2011.08.002DOI Listing
January 2012

Intussusception in adults with cystic fibrosis: a case series with review of the literature.

Dig Dis Sci 2011 Dec 16;56(12):3695-700. Epub 2011 Jun 16.

West Midlands Adult Cystic Fibrosis Centre, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS, UK.

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http://dx.doi.org/10.1007/s10620-011-1790-zDOI Listing
December 2011

Impact of lung transplantation on serum lipids in adults with cystic fibrosis.

J Heart Lung Transplant 2011 Feb;30(2):188-93

Toronto Adult Cystic Fibrosis Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.healun.2010.08.024DOI Listing
February 2011

Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis.

Gastroenterology 2011 Jan 9;140(1):153-61. Epub 2010 Nov 9.

Physiology and Experimental Medicine, The Research Institute, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2010.09.046DOI Listing
January 2011

TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis.

J Immunol 2010 Dec 10;185(12):7731-8. Epub 2010 Nov 10.

Department of Paediatrics, BC Children's Hospital and Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.4049/jimmunol.1001513DOI Listing
December 2010

Evidence of a generalized defect of acinar cell function in Shwachman-Diamond syndrome.

J Pediatr Gastroenterol Nutr 2010 Jul;51(1):8-13

Division of Gastroenterology, Hepatology, and Nutrition, University of Toronto, Canada.

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https://insights.ovid.com/crossref?an=00005176-201007000-000
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http://dx.doi.org/10.1097/MPG.0b013e3181d67e78DOI Listing
July 2010

Genetic testing in pancreatitis.

Gastroenterology 2010 Jun 20;138(7):2202-6, 2206.e1. Epub 2010 Apr 20.

Research Institute and Division of Gastroenterology, Hepatology and Nutrition Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2010.04.022DOI Listing
June 2010

The natural history of Shwachman-Diamond syndrome-associated liver disease from childhood to adulthood.

J Pediatr 2009 Dec 14;155(6):807-811.e2. Epub 2009 Aug 14.

Helsinki Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jpeds.2009.06.047DOI Listing
December 2009

Shwachman-Diamond syndrome is associated with low-turnover osteoporosis.

Bone 2007 Dec 5;41(6):965-72. Epub 2007 Sep 5.

Helsinki Medical Imaging Center, Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.bone.2007.08.035DOI Listing
December 2007

Patterns of GI disease in adulthood associated with mutations in the CFTR gene.

Gut 2007 Aug 19;56(8):1153-63. Epub 2007 Apr 19.

Paediatric Gastroenterology Unit, Hadassah Medical Organisation, Hebrew University, Jerusalem, Israel

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http://dx.doi.org/10.1136/gut.2004.062786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955522PMC
August 2007

Nutritional management of cystic fibrosis patients.

Curr Opin Clin Nutr Metab Care 2007 May;10(3):348-54

Respiratory Medicine, The Research Institute, Division of Gastroenterology and Nutrition, Department of Pediatrics, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MCO.0b013e3280a94f80DOI Listing
May 2007

Long-term docosahexaenoic acid therapy in a congenic murine model of cystic fibrosis.

Am J Physiol Gastrointest Liver Physiol 2007 Mar 9;292(3):G839-48. Epub 2006 Nov 9.

Program in Integrative Biology, The Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://www.physiology.org/doi/10.1152/ajpgi.00582.2005
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http://dx.doi.org/10.1152/ajpgi.00582.2005DOI Listing
March 2007

Enteric-coated pancreatic enzyme with bicarbonate is equal to standard enteric-coated enzyme in treating malabsorption in cystic fibrosis.

J Pediatr Gastroenterol Nutr 2006 Mar;42(3):256-61

Division of Respiratory Medicine, Department of Pediatrics, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/01.mpg.0000189356.93784.01DOI Listing
March 2006

Towards the ideal quantitative pancreatic function test: analysis of test variables that influence validity.

Clin Gastroenterol Hepatol 2006 Jan;4(1):90-7

Department of Gastroenterology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/s1542-3565(05)00852-9DOI Listing
January 2006

Failure of conventional strategies to improve nutritional status in malnourished adolescents and adults with cystic fibrosis.

J Pediatr 2005 Sep;147(3):399-401

Division of Respiratory Medicine, and Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S002234760500595
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http://dx.doi.org/10.1016/j.jpeds.2005.06.038DOI Listing
September 2005

Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome.

J Biol Chem 2005 May 8;280(19):19221-9. Epub 2005 Feb 8.

Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M414656200DOI Listing
May 2005

Combining unprotected pancreatic enzymes with pH-sensitive enteric-coated microspheres does not improve nutrient digestion in patients with cystic fibrosis.

J Pediatr 2005 Apr;146(4):489-93

Division of Respiratory Medicine, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.1016/j.jpeds.2004.10.063DOI Listing
April 2005

The era of position statements and consensus documents: A source of clarity or confusion?

Paediatr Child Health 2004 Dec;9(10):691

Program in Integrative Biology, The Research Institute, Division of Gastroenterology and Nutrition, The Hospital for Sick Children, and the Department of Pediatrics, University of Toronto, Toronto, Ontario;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724140PMC
http://dx.doi.org/10.1093/pch/9.10.691DOI Listing
December 2004

Analysis of cystic fibrosis gener product (CFTR) function in patients with pancreas divisum and recurrent acute pancreatitis.

Am J Gastroenterol 2004 Aug;99(8):1557-62

Division of Gastroenterology and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2004.30834.xDOI Listing
August 2004

Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation.

Gastroenterology 2004 Feb;126(2):576-85

Familial Gastrointestinal Cancer Registry and Centre for Cancer Genetics and Department of Surgery, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1053/j.gastro.2003.11.008DOI Listing
February 2004

Pharmacologic approaches to correcting the basic defect in cystic fibrosis.

N Engl J Med 2003 Oct;349(15):1401-4

Program in Cell Biology, Research Institute, Hospital for Sick Children, Toronto.

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http://dx.doi.org/10.1056/NEJMp038113DOI Listing
October 2003

Increased prevalence of CFTR mutations and variants and decreased chloride secretion in primary sclerosing cholangitis.

Hum Genet 2003 Aug 3;113(3):286-92. Epub 2003 Jun 3.

Department of Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Dana 532, 330 Brookline Avenue, Boston, MA 02215, USA.

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http://link.springer.com/10.1007/s00439-003-0963-z
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http://dx.doi.org/10.1007/s00439-003-0963-zDOI Listing
August 2003

Mutations in SBDS are associated with Shwachman-Diamond syndrome.

Nat Genet 2003 Jan 23;33(1):97-101. Epub 2002 Dec 23.

Program in Genetics and Genomic Biology, Room 11-109A, Elm Wing Annex, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1038/ng1062DOI Listing
January 2003

Proper usage of pancreatic enzymes.

Curr Opin Pulm Med 2002 Nov;8(6):542-6

The Hospital for Sick Children, Division of Gastroenterology and Nutrition, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/00063198-200211000-00010DOI Listing
November 2002

What is cystic fibrosis?

N Engl J Med 2002 Aug;347(6):439-42

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http://dx.doi.org/10.1056/NEJMe020070DOI Listing
August 2002

Pathophysiologic basis of exocrine pancreatic dysfunction in childhood.

J Pediatr Gastroenterol Nutr 2002 Jul;35(1):8-21

Division of Gastroenterology and Nutrition, Department of Pediatrics, University of Toronto and Programs in Genetics, Genomic Biology and Integrative Biology, the Research Institute, the Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1097/00005176-200207000-00004DOI Listing
July 2002