Peter Pasceri

Peter Pasceri

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Peter Pasceri

Peter Pasceri

Publications by authors named "Peter Pasceri"

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Synaptic Dysfunction in Human Neurons With Autism-Associated Deletions in PTCHD1-AS.

Biol Psychiatry 2020 Jan 29;87(2):139-149. Epub 2019 Jul 29.

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948145PMC
January 2020

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons.

Stem Cell Reports 2018 11 1;11(5):1211-1225. Epub 2018 Nov 1.

Genetics & Genome Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3H7, Canada; McLaughlin Centre, University of Toronto, Toronto, ON M5S 3H7, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183042
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http://dx.doi.org/10.1016/j.stemcr.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235011PMC
November 2018

The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants.

CMAJ 2018 02;190(5):E126-E136

The Centre for Applied Genomics (Reuter, Walker, Thiruvahindrapuram, Whitney, Yuen, Trost, Paton, Pereira, Herbrick, Wintle, Merico, Howe, MacDonald, Lu, Nalpathamkalam, Sung, Wang, Patel, Pellecchia, J. Wei, Strug, Bell, Kellam, Mahtani, Hosseini, Fiume, Marshall, Buchanan, Scherer); Divisions of Clinical Pharmacology and Toxicology (I. Cohn), or Clinical, and Metabolic Genetics (Sondheimer, Weksberg, Shuman, Bowdin, Meyn, Monfared), The Hospital for Sick Children; Departments of Paediatrics (Sondheimer, R. Cohn) and Molecular Genetics (Yuen, Weksberg, Shuman, R. Cohn, Ellis, Meyn), University of Toronto; Deep Genomics Inc. (Merico); Department of Psychiatry (Bassett), University Health Network and Centre for Addiction and Mental Health, University of Toronto; Li Ka Shing Knowledge Institute (Bombard), St. Michael's Hospital; Institute of Health Policy, Management and Evaluation (Bombard), University of Toronto; Centre for Genetic Medicine (Stavropoulos, Bowdin, Ray, Monfared); Molecular Genetics Laboratory (Stavropoulos, Ray, Marshall), Division of Genome Diagnostics, Paediatric Laboratory Medicine; Developmental and Stem Cell Biology (Hildebrandt, W. Wei, Romm, Pasceri, Ellis); Ted Rogers Cardiac Genome Clinic (Hosseini); Cytogenetics Laboratory (Joseph-George), Division of Genome Diagnostics, Paediatric Laboratory Medicine, The Hospital for Sick Children; Departments of Biochemistry and Laboratory Medicine, and Pathobiology (Keeley), University of Toronto; DNAstack (Cook, Fiume); McLaughlin Centre (Lee, Scherer), University of Toronto; Medcan Health Management Inc. (Davies, Hazell); Dalla Lana School of Public Health (Szego), Department of Family and Community Medicine, and The Joint Centre for Bioethics, University of Toronto; Centre for Clinical Ethics (Szego), St. Joseph's Health Centre, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.171151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798982PMC
February 2018

MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells.

Neurobiol Dis 2015 Apr 30;76:37-45. Epub 2015 Jan 30.

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961150001
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http://dx.doi.org/10.1016/j.nbd.2015.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380613PMC
April 2015

Kinetics and epigenetics of retroviral silencing in mouse embryonic stem cells defined by deletion of the D4Z4 element.

Mol Ther 2013 Aug 11;21(8):1536-50. Epub 2013 Jun 11.

Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/mt.2013.131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734652PMC
August 2013

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation.

Hum Mol Genet 2011 Jun 3;20(11):2103-15. Epub 2011 Mar 3.

Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/hmg/ddr093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090191PMC
June 2011

EOS lentiviral vector selection system for human induced pluripotent stem cells.

Nat Protoc 2009 ;4(12):1828-44

Developmental and Stem Cell Biology Program, SickKids, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nprot.2009.201DOI Listing
March 2010

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides.

Mol Ther 2005 Apr;11(4):591-9

Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.ymthe.2004.11.012DOI Listing
April 2005

Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications.

Mol Ther 2004 Jul;10(1):27-36

Developmental Biology Program, Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8.

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http://dx.doi.org/10.1016/j.ymthe.2004.04.007DOI Listing
July 2004

Retrovirus silencer blocking by the cHS4 insulator is CTCF independent.

Nucleic Acids Res 2003 Sep;31(18):5317-23

Developmental Biology Program, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC203325PMC
http://dx.doi.org/10.1093/nar/gkg742DOI Listing
September 2003

LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of beta -globin intron-2.

Blood 2003 Feb 26;101(4):1603-10. Epub 2002 Sep 26.

Developmental Biology Program, Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1182/blood-2002-07-2086DOI Listing
February 2003

Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes.

Eur J Immunol 2003 Feb;33(2):546-55

The Hospital For Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/immu.200310031DOI Listing
February 2003