Publications by authors named "Peter P Ruvolo"

43Publications

LGALS1 acts as a pro-survival molecule in AML.

Biochim Biophys Acta Mol Cell Res 2020 10 23;1867(10):118785. Epub 2020 Jun 23.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States of America; Section of Molecular Hematology and Therapy, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States of America.

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http://dx.doi.org/10.1016/j.bbamcr.2020.118785DOI Listing
October 2020

TP53/miR-34a-associated signaling targets expression in human pancreatic cancer.

Aging (Albany NY) 2020 01 27;12(3):2777-2797. Epub 2020 Jan 27.

Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834,USA.

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http://dx.doi.org/10.18632/aging.102776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041729PMC
January 2020

LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML.

EBioMedicine 2019 Jun 16;44:126-137. Epub 2019 May 16.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA; Division of Molecular Hematology and Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604360PMC
June 2019

Galectins as regulators of cell survival in the leukemia niche.

Authors:
Peter P Ruvolo

Adv Biol Regul 2019 01 12;71:41-54. Epub 2018 Sep 12.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbior.2018.09.003DOI Listing
January 2019

Role of protein phosphatases in the cancer microenvironment.

Authors:
Peter P Ruvolo

Biochim Biophys Acta Mol Cell Res 2019 01 17;1866(1):144-152. Epub 2018 Jul 17.

Department of Leukemia, University of Texas MD Anderson Cancer Center, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2018.07.006DOI Listing
January 2019

Role of MSC-derived galectin 3 in the AML microenvironment.

Biochim Biophys Acta Mol Cell Res 2018 07 12;1865(7):959-969. Epub 2018 Apr 12.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Section of Molecular Hematology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.bbamcr.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936474PMC
July 2018

GSK-3 as a novel prognostic indicator in leukemia.

Authors:
Peter P Ruvolo

Adv Biol Regul 2017 08 8;65:26-35. Epub 2017 May 8.

Department of Leukemia, Unit 448, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jbior.2017.05.001DOI Listing
August 2017

Editorial: The Emerging Role for PP2A in Hematologic Malignancies.

Authors:
Peter P Ruvolo

Front Oncol 2016 31;6:195. Epub 2016 Aug 31.

Department of Leukemia, University of Texas MD Anderson Cancer Center , Houston, TX , USA.

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http://dx.doi.org/10.3389/fonc.2016.00195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005333PMC
September 2016

The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance.

Authors:
Peter P Ruvolo

BBA Clin 2016 Dec 3;6:87-99. Epub 2016 Aug 3.

Department of Leukemia, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 0425, Houston, TX 77030, United States.

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http://dx.doi.org/10.1016/j.bbacli.2016.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986044PMC
December 2016

Introduction to tumor microenvironment regulation of cancer cell survival, metastasis, inflammation, and immune surveillance.

Biochim Biophys Acta 2016 Mar 23;1863(3):379-381. Epub 2015 Dec 23.

Department of Leukemia, Section of Molecular Hematology and Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.12.015DOI Listing
March 2016

Galectin 3 as a guardian of the tumor microenvironment.

Authors:
Peter P Ruvolo

Biochim Biophys Acta 2016 Mar 8;1863(3):427-437. Epub 2015 Aug 8.

Department of Leukemia, University of Texas MD Anderson Cancer Center, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.08.008DOI Listing
March 2016

The Interplay between PP2A and microRNAs in Leukemia.

Authors:
Peter P Ruvolo

Front Oncol 2015 20;5:43. Epub 2015 Feb 20.

Department of Leukemia, University of Texas MD Anderson Cancer Center , Houston, TX , USA.

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http://dx.doi.org/10.3389/fonc.2015.00043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335100PMC
March 2015

The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.

Biochim Biophys Acta 2014 Sep 21;1843(9):1969-77. Epub 2014 May 21.

Division of Molecular Hematology, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2014.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165504PMC
September 2014

Preclinical and early clinical evaluation of the oral AKT inhibitor, MK-2206, for the treatment of acute myelogenous leukemia.

Clin Cancer Res 2014 Apr 28;20(8):2226-35. Epub 2014 Feb 28.

Authors' Affiliations: Department of Leukemia; Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Hematology/Department of Medicine; Department of Epidemiology, University of Washington, Seattle, Washington; and National Cancer Institute, Rockville, Maryland.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-1978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989412PMC
April 2014

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

Cancer Discov 2014 Mar 17;4(3):362-75. Epub 2013 Dec 17.

Departments of 1Leukemia, 2Pediatrics, and 3Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; 4Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; 5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; 6The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio; 7AbbVie Inc., North Chicago, Illinois; and 8Department of Laboratory Medicine, University of California San Francisco, San Francisco, California; 9Department of Internal Medicine III, University Hospital of Ulm, Ulm; 10MLL Munich Leukemia Laboratory, Munich, Germany.

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http://research4.dfci.harvard.edu/letai/Publications/2013-12
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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-13-0609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975047PMC
March 2014

Pharmacologic protein kinase Cα inhibition uncouples human platelet-stimulated angiogenesis from collagen-induced aggregation.

J Pharmacol Exp Ther 2013 Apr 5;345(1):15-24. Epub 2013 Feb 5.

Faculty of Pharmacy and Pharmaceutical, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1124/jpet.112.200881DOI Listing
April 2013

Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells.

J Signal Transduct 2010 Jan;2010:584657

Section of Signal Transduction and Apoptosis, Hormel Institute, University of Minnesota, Austin, MN 55912, USA.

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http://dx.doi.org/10.1155/2010/584657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938797PMC
January 2010

PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cells.

J Biol Chem 2008 Dec 28;283(51):35474-85. Epub 2008 Oct 28.

Section of Signal Transduction and Apoptosis, University of Minnesota Hormel Institute, Austin, Minnesota 55912, USA.

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http://dx.doi.org/10.1074/jbc.M800951200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602900PMC
December 2008

p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.

J Cell Biochem 2008 Sep;105(1):167-75

Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/jcb.21809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575069PMC
September 2008

Mitochondrial protein phosphatase 2A regulates cell death induced by simulated ischemia in kidney NRK-52E cells.

Cell Cycle 2007 Oct 12;6(19):2377-85. Epub 2007 Jul 12.

Division of Cell Signaling, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center, Houston, Texas, USA.

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http://dx.doi.org/10.4161/cc.6.19.4737DOI Listing
October 2007

LPS/IFNgamma-induced RAW 264.7 apoptosis is regulated by both nitric oxide-dependent and -independent pathways involving JNK and the Bcl-2 family.

Cell Cycle 2007 Jul 14;6(14):1772-8. Epub 2007 Mar 14.

Division of Cell Signaling, Institute of Molecular Medicine, Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, Texas, USA.

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http://dx.doi.org/10.4161/cc.6.14.4438DOI Listing
July 2007

Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase.

Cancer Res 2004 Nov;64(21):7852-6

Division of Cell Signaling, Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1552DOI Listing
November 2004

Expression of inducible Bcl-X(S) in myeloid leukemia: compensatory upregulation of Bcl-X(L) and Bcl-2 prevents apoptosis and chemosensitization.

Cancer Biol Ther 2004 Mar 29;3(3):340-7. Epub 2004 Mar 29.

Department of Gastroenterology, Hepatology and Endocrinolog, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.4161/cbt.3.3.734DOI Listing
March 2004

Intracellular signal transduction pathways activated by ceramide and its metabolites.

Authors:
Peter P Ruvolo

Pharmacol Res 2003 May;47(5):383-92

Institute of Molecular Medicine, University of Texas Health Science Center, IBT-900, 2121 W. Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/s1043-6618(03)00050-1DOI Listing
May 2003

Protein kinase C-dependent phosphorylation and mitochondrial translocation of aldose reductase.

FEBS Lett 2003 Jan;534(1-3):175-9

Division of Anesthesiology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77550, USA.

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http://dx.doi.org/10.1016/s0014-5793(02)03834-6DOI Listing
January 2003

Bryostatin-I: an antineoplastic treasure from the deep?

Cancer Biol Ther 2002 Jul-Aug;1(4):417-9

University of Florida Shands Cancer Center, Department of Medicine, University of Florida College of Medicine, Gainesville 32610-0232, USA.

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http://dx.doi.org/10.4161/cbt.1.4.20DOI Listing
July 2003

A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function.

J Biol Chem 2002 Jun 2;277(25):22847-52. Epub 2002 Apr 2.

Shands Cancer Center and the Department of Medicine, the University of Florida, Gainesville, Florida 32610-0232, USA.

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http://dx.doi.org/10.1074/jbc.M201830200DOI Listing
June 2002