Peter Mundel

Peter Mundel

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Peter Mundel

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GDC-0879, a BRAF Inhibitor, Protects Kidney Podocytes from Death.

Cell Chem Biol 2018 02 14;25(2):175-184.e4. Epub 2017 Dec 14.

Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819995PMC
February 2018

Podocytes and the quest for precision medicines for kidney diseases.

Authors:
Peter Mundel

Pflugers Arch 2017 Aug 23;469(7-8):1029-1037. Epub 2017 Jun 23.

Goldfinch Bio, 215 First Street, 4th Floor, Cambridge, MA, 02142, USA.

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http://dx.doi.org/10.1007/s00424-017-2015-xDOI Listing
August 2017

Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes.

J Am Soc Nephrol 2017 Mar 14;28(3):837-851. Epub 2016 Sep 14.

Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.1681/ASN.2016040414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328162PMC
March 2017

Personalized Comments on Challenges and Opportunities in Kidney Disease Therapeutics: The Glom-NExT Symposium.

Semin Nephrol 2016 11;36(6):448

Broad Institute of Massachusetts Institute of Technology, and Harvard, Cambridge, MA; Center for Human Genetic Research and Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.semnephrol.2016.09.005DOI Listing
November 2016

Podocyte-Targeted Treatment for Proteinuric Kidney Disease.

Authors:
Peter Mundel

Semin Nephrol 2016 11;36(6):459-462

Goldfinch Bio, Cambridge, MA. Electronic address:

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http://dx.doi.org/10.1016/j.semnephrol.2016.09.008DOI Listing
November 2016

Rewiring neuronal microcircuits of the brain via spine head protrusions--a role for synaptopodin and intracellular calcium stores.

Acta Neuropathol Commun 2016 Apr 22;4:38. Epub 2016 Apr 22.

Integrated Program in Neuroscience, McGill University, Montreal, QC, H3G 0B1, Canada.

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http://dx.doi.org/10.1186/s40478-016-0311-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840984PMC
April 2016

Developing therapeutic 'arrows' with the precision of William Tell: the time has come for targeted therapies in kidney disease.

Curr Opin Nephrol Hypertens 2015 Jul;24(4):388-92

aDepartment of Medicine, Massachusetts General Hospital and Harvard Medical School bDepartment of Medicine, Glom-NExT Center for Glomerular Kidney Disease and Novel Experimental Therapeutics, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499164PMC
July 2015

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.

Science 2015 Jul;349(6247):1261669

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Charlestown, MA 02129, USA. Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1126/science.1261669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215039PMC
July 2015

Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics.

Nat Commun 2013 ;4:2863

1] Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02129, USA [2].

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http://dx.doi.org/10.1038/ncomms3863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698162PMC
October 2014

MAGI-2 scaffold protein is critical for kidney barrier function.

Proc Natl Acad Sci U S A 2014 Oct 30;111(41):14876-81. Epub 2014 Sep 30.

Human Oncology and Pathogenesis Program, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1417297111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205655PMC
October 2014

Extensive podocyte loss triggers a rapid parietal epithelial cell response.

J Am Soc Nephrol 2014 May 12;25(5):927-38. Epub 2013 Dec 12.

Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; and Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

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http://dx.doi.org/10.1681/ASN.2013070687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005306PMC
May 2014

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes.

Diabetologia 2014 Jan 26;57(1):224-35. Epub 2013 Oct 26.

Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Universiteitssingel 50, P.O. Box 616 (box 14), 6200 MD, Maastricht, the Netherlands,

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http://dx.doi.org/10.1007/s00125-013-3088-5DOI Listing
January 2014

Abatacept in B7-1-positive proteinuric kidney disease.

N Engl J Med 2013 Dec 8;369(25):2416-23. Epub 2013 Nov 8.

From the Department of Medicine, Massachusetts General Hospital and Harvard Medical School (C.-C.Y., A.W., S.H., D.B., M.A.A., A.G., P.M.), Department of Pathology, Brigham and Women's Hospital and Harvard Medical School (A.W.), and Division of Nephrology, Children's Hospital Boston (P.F.) - all in Boston; the Graduate Institute of Medicine, College of Medicine (C.-C.Y.), and Department of Internal Medicine (J.-M.C., H.-C.C.), Kaohsiung Medical University, Kaohsiung, Taiwan; the Division of Nephrology and Hypertension (A.F., D.M., M.H.F., C.F., V.G.) and Lilian Jean Kaplan Division of Kidney-Pancreas Transplantation, Miami Transplant Institute, Department of Surgery (J.S., L.C., G.C., G.W.B.), University of Miami Miller School of Medicine, Miami; the Division of Nephrology, Mount Sinai School of Medicine, New York (K.N.C.); and Pediatric Nephrology, Children's Hospital, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (J.O.).

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http://dx.doi.org/10.1056/NEJMoa1304572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951406PMC
December 2013

Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2.

Am J Pathol 2013 Sep 16;183(3):735-44. Epub 2013 Jul 16.

Laboratory of Molecular Nephrology, Department of Biomedicine, University Hospital, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.ajpath.2013.05.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763774PMC
September 2013

Essential role for synaptopodin in dendritic spine plasticity of the developing hippocampus.

J Neurosci 2013 Jul;33(30):12510-8

Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York 10595, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2983-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721850PMC
July 2013

Yes-associated protein (YAP) promotes cell survival by inhibiting proapoptotic dendrin signaling.

J Biol Chem 2013 Jun 10;288(24):17057-62. Epub 2013 May 10.

Division of Nephrology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1074/jbc.C113.457390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682510PMC
June 2013

Calcium regulates podocyte actin dynamics.

Semin Nephrol 2012 Jul;32(4):319-26

Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, 149 13th St, Charlestown, MA 02129, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S027092951200081
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http://dx.doi.org/10.1016/j.semnephrol.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581337PMC
July 2012

Cell biology and pathology of podocytes.

Annu Rev Physiol 2012 4;74:299-323. Epub 2011 Nov 4.

Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1146/annurev-physiol-020911-153238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600372PMC
June 2012

Balancing calcium signals through TRPC5 and TRPC6 in podocytes.

J Am Soc Nephrol 2011 Nov 6;22(11):1969-80. Epub 2011 Oct 6.

Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1681/ASN.2011040370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231779PMC
November 2011

Stimulation of the calcium-sensing receptor stabilizes the podocyte cytoskeleton, improves cell survival, and reduces toxin-induced glomerulosclerosis.

Kidney Int 2011 Sep 20;80(5):483-92. Epub 2011 Apr 20.

Division of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/ki.2011.105DOI Listing
September 2011

Role of angiotensin II in the development of nephropathy and podocytopathy of diabetes.

Curr Diabetes Rev 2011 Jan;7(1):3-7

Department of Medicine, Leonard Miller School of Medicine, University of Miami, 1580 NW 10th Avenue, Miami, FL 33136, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690294PMC
January 2011

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids.

Am J Physiol Renal Physiol 2010 Oct 28;299(4):F821-9. Epub 2010 Jul 28.

Dept. of Biomedicine, Molecular Nephrology, Univ. Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland.

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http://dx.doi.org/10.1152/ajprenal.00196.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957252PMC
October 2010

Proteinuria: an enzymatic disease of the podocyte?

Kidney Int 2010 Apr 18;77(7):571-80. Epub 2009 Nov 18.

Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1038/ki.2009.424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109304PMC
April 2010

Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria.

Curr Opin Nephrol Hypertens 2009 Nov;18(6):539-45

Division of Nephrology and Hypertension, University of Miami L Miller School of Medicine, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1097/MNH.0b013e32832f7002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907246PMC
November 2009

Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.

J Am Soc Nephrol 2008 Nov 5;19(11):2159-69. Epub 2008 Sep 5.

Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1681/ASN.2008030312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573016PMC
November 2008

Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease.

Proc Natl Acad Sci U S A 2008 Sep 4;105(37):14106-11. Epub 2008 Sep 4.

Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0801146105
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http://dx.doi.org/10.1073/pnas.0801146105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529330PMC
September 2008

Modification of kidney barrier function by the urokinase receptor.

Nat Med 2008 Jan 16;14(1):55-63. Epub 2007 Dec 16.

Nephrology Division and Program in Glomerular Disease, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/nm1696DOI Listing
January 2008

Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.

Mol Cell Biol 2007 Dec 8;27(23):8215-27. Epub 2007 Oct 8.

Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1128/MCB.00950-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169179PMC
December 2007

Dual effects of RAS blockade on blood pressure and podocyte function.

Curr Hypertens Rep 2007 Nov;9(5):403-8

Division of Nephrology, Program in Glomerular Disease, Massachusetts General Hospital and Harvard Medical School, CNY-149, 13th Street, Suite 8214, Boston, MA 02129, USA.

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November 2007

Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton.

Trends Cell Biol 2007 Sep 4;17(9):428-37. Epub 2007 Sep 4.

Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.cell.com/trends/cell-biology/pdf/S0962-8924(07)00
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http://linkinghub.elsevier.com/retrieve/pii/S096289240700167
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http://dx.doi.org/10.1016/j.tcb.2007.06.006DOI Listing
September 2007

Plasticity of synaptopodin and the spine apparatus organelle in the rat fascia dentata following entorhinal cortex lesion.

J Comp Neurol 2006 Nov;499(3):471-84

Institute of Clinical Neuroanatomy, J.W. Goethe-University, D-60590 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1002/cne.21103DOI Listing
November 2006

Short-term ischemia usually used for ischemic preconditioning causes loss of dendritic integrity after long-term survival in the gerbil hippocampus.

Brain Res 2006 Sep 31;1112(1):222-6. Epub 2006 Jul 31.

Department of Neuropathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.brainres.2006.07.004DOI Listing
September 2006

Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP.

Am J Physiol Renal Physiol 2006 Aug 4;291(2):F422-8. Epub 2006 Apr 4.

Dept. of Pediatrics/Nephrology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Forchheimer Bldg., Rm. 708, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1152/ajprenal.00448.2005DOI Listing
August 2006

Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling.

Nat Cell Biol 2006 May 16;8(5):485-91. Epub 2006 Apr 16.

Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1038/ncb1400DOI Listing
May 2006

Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin.

J Clin Invest 2006 May 20;116(5):1337-45. Epub 2006 Apr 20.

Department of Pathology and Immunology and Department of Medicine, Renal Division, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1172/JCI27400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440708PMC
May 2006

TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes.

J Am Soc Nephrol 2005 Nov 5;16(11):3211-21. Epub 2005 Oct 5.

Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1681/ASN.2004121055DOI Listing
November 2005

Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival.

J Am Soc Nephrol 2005 Jul 4;16(7):1966-76. Epub 2005 May 4.

707B Scaife Hall, Department of Pathology, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1681/ASN.2004121112DOI Listing
July 2005

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.

J Clin Invest 2005 May 1;115(5):1188-98. Epub 2005 Apr 1.

Department of Medicine, Albert Einstein College of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI23371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1070637PMC
May 2005

Expression and regulation of adrenomedullin in renal glomerular podocytes.

Biochem Biophys Res Commun 2005 Apr;330(1):178-85

Department of Nephrology and Endocrinology, University of Tokyo Graduate School of Medicine, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.02.142DOI Listing
April 2005

Cross-reactivity of human lupus anti-DNA antibodies with alpha-actinin and nephritogenic potential.

Arthritis Rheum 2005 Feb;52(2):522-30

Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1002/art.20862DOI Listing
February 2005

Danger signaling by glomerular podocytes defines a novel function of inducible B7-1 in the pathogenesis of nephrotic syndrome.

J Am Soc Nephrol 2004 Sep;15(9):2246-8

Division of Nephrology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://www.jasn.org/cgi/doi/10.1097/01.ASN.0000136312.46464.
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http://dx.doi.org/10.1097/01.ASN.0000136312.46464.33DOI Listing
September 2004

Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin.

J Biol Chem 2004 Aug 14;279(33):34827-32. Epub 2004 Jun 14.

Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1074/jbc.M401973200DOI Listing
August 2004

A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis.

J Biol Chem 2004 Aug 22;279(35):37004-12. Epub 2004 Jun 22.

Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10461, USA.

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http://dx.doi.org/10.1074/jbc.M403534200DOI Listing
August 2004

Differentiation-induced cultured podocytes express endocytically active megalin, a heymann nephritis antigen.

Nephron Exp Nephrol 2004 ;96(2):e52-8

Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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https://www.karger.com/Article/FullText/76404
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http://dx.doi.org/10.1159/000076404DOI Listing
May 2004

A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus.

J Biol Chem 2004 Apr 20;279(14):14398-408. Epub 2004 Jan 20.

Departments of Medicine and Physiology and Biophysics, School of Medicine, Case Western Reserve University and Rammelkamp Center for Research and Education, MetroHealth System Campus, Cleveland, Ohio 44109-1998, USA.

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http://dx.doi.org/10.1074/jbc.M314155200DOI Listing
April 2004

Podocyte biology and the emerging understanding of podocyte diseases.

Am J Nephrol 2003 Sep-Oct;23(5):353-60. Epub 2003 Aug 12.

Department of Pathology, The Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1159/000072917DOI Listing
February 2004

Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome.

Pediatr Nephrol 2004 Feb 13;19(2):130-7. Epub 2003 Dec 13.

Division of Nephrology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1007/s00467-003-1367-yDOI Listing
February 2004

Activation of a local tissue angiotensin system in podocytes by mechanical strain.

Kidney Int 2004 Jan;65(1):30-9

Department of Medicine, Division of Nephrology, University of Washington School of Medicine, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2004.00362.xDOI Listing
January 2004

IFN-inducible protein-10 has a differential role in podocyte during Thy 1.1 glomerulonephritis.

J Am Soc Nephrol 2003 Dec;14(12):3111-26

Department of Cell Biology, Institute of Nephrology, Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1097/01.asn.0000097371.64671.65DOI Listing
December 2003

Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes.

J Am Soc Nephrol 2003 Dec;14(12):3178-87

Division of Nephrology and Hypertension, Department of Internal Medicine, Harbor-UCLA Research and Education Institute, Torrance, California 90509, USA.

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http://dx.doi.org/10.1097/01.asn.0000099702.16315.deDOI Listing
December 2003

The role of podocytes in glomerular pathobiology.

Clin Exp Nephrol 2003 Dec;7(4):255-9

Division of Nephrology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://link.springer.com/10.1007/s10157-003-0259-6
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http://dx.doi.org/10.1007/s10157-003-0259-6DOI Listing
December 2003

Urinary podocytes: lost and found alive.

Authors:
Peter Mundel

Kidney Int 2003 Oct;64(4):1529-30

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http://dx.doi.org/10.1046/j.1523-1755.2003.00339.xDOI Listing
October 2003

Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcome.

Oncogene 2003 Aug;22(34):5298-305

Division of Molecular Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, NY 10021, USA.

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http://dx.doi.org/10.1038/sj.onc.1206616DOI Listing
August 2003

Sp1 and Sp3 transcription factors synergistically regulate HGF receptor gene expression in kidney.

Am J Physiol Renal Physiol 2003 Jan;284(1):F82-94

Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1152/ajprenal.00200.2002DOI Listing
January 2003

Podocyte biology and response to injury.

J Am Soc Nephrol 2002 Dec;13(12):3005-15

Division of Nephrology, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1097/01.asn.0000039661.06947.fdDOI Listing
December 2002

Glomerular endothelial fenestrae in vivo are not formed from caveolae.

J Am Soc Nephrol 2002 Nov;13(11):2639-47

Department of Medicine, Division of Nephrology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://jasn.asnjournals.org/content/13/11/2639.full.pdf
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http://dx.doi.org/10.1097/01.asn.0000033277.32822.23DOI Listing
November 2002

Inhibitory smads and tgf-Beta signaling in glomerular cells.

J Am Soc Nephrol 2002 Nov;13(11):2657-66

Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1097/01.asn.0000033276.06451.50DOI Listing
November 2002

Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.

Kidney Int 2002 Sep;62(3):901-13

Renal-Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania, 700 Clinical Research Building, 415 Curie Boulevard, Philadelphia, PA 19104-4218, USA.

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http://dx.doi.org/10.1046/j.1523-1755.2002.00528.xDOI Listing
September 2002

Role of nephrin in renal disease including diabetic nephropathy.

Semin Nephrol 2002 Sep;22(5):393-8

JDRF Centre for Diabetic Complications, Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre (Repatriation Campus), Banksia St, West Heidelberg, Australia.

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September 2002

Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1.

J Biol Chem 2002 Aug 31;277(33):30183-90. Epub 2002 May 31.

Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, 48109-0650, USA.

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http://dx.doi.org/10.1074/jbc.M203072200DOI Listing
August 2002

A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development.

J Am Soc Nephrol 2002 Aug;13(8):2058-67

Department of Medicine and Laboratory for Skeletal Disorders and Rehabilitation, Department of Orthopedic Surgery, Children's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1097/01.asn.0000022420.48110.4bDOI Listing
August 2002

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

J Am Soc Nephrol 2002 Mar;13(3):630-8

Children's Renal Unit and Academic Renal Unit, University of Bristol, Southmead Hospital, Bristol, UK.

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March 2002