Peter M Visscher

Peter M Visscher

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Peter M Visscher

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"Arte et Labore"-A Blackburn Rovers fan's legacy in human complex trait genetics.

J Anim Breed Genet 2019 Jul;136(4):273-278

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/jbg.12384DOI Listing
July 2019

Tissue-specific sex-differences in human gene expression.

Hum Mol Genet 2019 May 2. Epub 2019 May 2.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1093/hmg/ddz090DOI Listing
May 2019

OSCA: a tool for omic-data-based complex trait analysis.

Genome Biol 2019 05 28;20(1):107. Epub 2019 May 28.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.

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http://dx.doi.org/10.1186/s13059-019-1718-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537380PMC
May 2019

From R.A. Fisher's 1918 Paper to GWAS a Century Later.

Genetics 2019 04;211(4):1125-1130

Centre for AgriBioscience, Department of Economic Development, Jobs, Transport and Resources, Bundoora, Victoria, Australia 3083.

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http://dx.doi.org/10.1534/genetics.118.301594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456325PMC
April 2019

Complex Trait Prediction from Genome Data: Contrasting EBV in Livestock to PRS in Humans: Genomic Prediction.

Genetics 2019 04;211(4):1131-1141

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4067, Australia.

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http://dx.doi.org/10.1534/genetics.119.301859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456317PMC
April 2019

Genome-wide association study of medication-use and associated disease in the UK Biobank.

Nat Commun 2019 04 23;10(1):1891. Epub 2019 Apr 23.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-019-09572-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478889PMC
April 2019

Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes.

Nat Genet 2019 02 14;51(2):327-334. Epub 2019 Jan 14.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0313-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358510PMC
February 2019

Leveraging GWAS for complex traits to detect signatures of natural selection in humans.

Curr Opin Genet Dev 2018 12 16;53:9-14. Epub 2018 Jun 16.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2018.05.012DOI Listing
December 2018

Assortative mating on complex traits revisited: Double first cousins and the X-chromosome.

Theor Popul Biol 2018 12 11;124:51-60. Epub 2018 Oct 11.

Institute for Molecular Bioscience, The University of Queensland, Brisbane 4072, Australia; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.

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http://dx.doi.org/10.1016/j.tpb.2018.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296780PMC
December 2018

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.

Nat Commun 2018 12 20;9(1):5407. Epub 2018 Dec 20.

Institute for Molecular Bioscience, University of Queensland, Queensland, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-07862-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302097PMC
December 2018

Imprint of assortative mating on the human genome.

Nat Hum Behav 2018 12 26;2(12):948-954. Epub 2018 Nov 26.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://www.nature.com/articles/s41562-018-0476-3
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http://dx.doi.org/10.1038/s41562-018-0476-3DOI Listing
December 2018

Epigenetic signatures of starting and stopping smoking.

EBioMedicine 2018 Nov 30;37:214-220. Epub 2018 Oct 30.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.10.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286188PMC
November 2018

Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness.

Nat Commun 2018 11 20;9(1):4953. Epub 2018 Nov 20.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-07400-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244080PMC
November 2018

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

Nat Genet 2018 07 23;50(8):1112-1121. Epub 2018 Jul 23.

National Bureau of Economic Research, Cambridge, MA, USA.

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http://www.nature.com/articles/s41588-018-0147-3
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http://dx.doi.org/10.1038/s41588-018-0147-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393768PMC
July 2018

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model.

Cell 2018 06;173(7):1573-1580

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia; Queensland Brain Institute, The University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.cell.2018.05.051DOI Listing
June 2018

Misestimation of heritability and prediction accuracy of male-pattern baldness.

Nat Commun 2018 06 29;9(1):2537. Epub 2018 Jun 29.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04807-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026149PMC
June 2018

Global genetic differentiation of complex traits shaped by natural selection in humans.

Nat Commun 2018 05 14;9(1):1865. Epub 2018 May 14.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951811PMC
May 2018

Global genetic differentiation of complex traits shaped by natural selection in humans.

Nat Commun 2018 05 14;9(1):1865. Epub 2018 May 14.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951811PMC
May 2018

Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio.

Genetics 2018 04 2;208(4):1397-1408. Epub 2018 Feb 2.

Institute for Molecular Bioscience, University of Queensland, Brisbane 4072, Australia.

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http://dx.doi.org/10.1534/genetics.117.300360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887138PMC
April 2018

Gene networks associated with non-syndromic intellectual disability.

J Neurogenet 2018 03 4;32(1):6-14. Epub 2017 Dec 4.

a Mater Research Institute, The University of Queensland , Woolloongabba , Australia.

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http://dx.doi.org/10.1080/01677063.2017.1404058DOI Listing
March 2018

Reply to Kardos et al.: Estimation of inbreeding depression from SNP data.

Proc Natl Acad Sci U S A 2018 03 21;115(11):E2494-E2495. Epub 2018 Feb 21.

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia;

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http://dx.doi.org/10.1073/pnas.1718598115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856540PMC
March 2018

A multi-trait Bayesian method for mapping QTL and genomic prediction.

Genet Sel Evol 2018 03 24;50(1):10. Epub 2018 Mar 24.

Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, 3052, Australia.

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http://dx.doi.org/10.1186/s12711-018-0377-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866527PMC
March 2018

Genetic Stratification to Identify Risk Groups for Alzheimer's Disease.

J Alzheimers Dis 2017 ;57(1):275-283

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.3233/JAD-161070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345653PMC
February 2018

Evidence of directional and stabilizing selection in contemporary humans.

Proc Natl Acad Sci U S A 2018 01 18;115(1):151-156. Epub 2017 Dec 18.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia;

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http://dx.doi.org/10.1073/pnas.1707227114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776788PMC
January 2018

Causal associations between risk factors and common diseases inferred from GWAS summary data.

Nat Commun 2018 01 15;9(1):224. Epub 2018 Jan 15.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-017-02317-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768719PMC
January 2018

Testing Two Evolutionary Theories of Human Aging with DNA Methylation Data.

Genetics 2017 12 30;207(4):1547-1560. Epub 2017 Aug 30.

Department of Human Genetics, Emory University School of Medicine, Emory University, Atlanta, Georgia 30322.

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http://dx.doi.org/10.1534/genetics.117.300217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714465PMC
December 2017

Challenges in understanding common disease.

Authors:
Peter M Visscher

Genome Med 2017 12 18;9(1):112. Epub 2017 Dec 18.

Institute for Molecular Bioscience and Queensland Brain Institute, University of Queensland, St Lucia, QLD, 4072, Australia.

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http://dx.doi.org/10.1186/s13073-017-0506-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733735PMC
December 2017

Detection and quantification of inbreeding depression for complex traits from SNP data.

Proc Natl Acad Sci U S A 2017 08 26;114(32):8602-8607. Epub 2017 Jul 26.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia;

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http://dx.doi.org/10.1073/pnas.1621096114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558994PMC
August 2017

Concepts, estimation and interpretation of SNP-based heritability.

Nat Genet 2017 Aug;49(9):1304-1310

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.3941DOI Listing
August 2017

10 Years of GWAS Discovery: Biology, Function, and Translation.

Am J Hum Genet 2017 Jul;101(1):5-22

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1016/j.ajhg.2017.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501872PMC
July 2017

Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traits.

Int J Epidemiol 2017 Jul 17. Epub 2017 Jul 17.

Institute for Molecular Bioscience.

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http://dx.doi.org/10.1093/ije/dyx129DOI Listing
July 2017

Inference on the Genetic Basis of Eye and Skin Color in an Admixed Population via Bayesian Linear Mixed Models.

Genetics 2017 06 4;206(2):1113-1126. Epub 2017 Apr 4.

Institute for Molecular Bioscience, University of Queensland, St. Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1534/genetics.116.193383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499166PMC
June 2017

Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing data.

Genome Biol 2017 05 16;18(1):86. Epub 2017 May 16.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://genomebiology.biomedcentral.com/articles/10.1186/s130
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http://dx.doi.org/10.1186/s13059-017-1216-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432979PMC
May 2017

Genetic signatures of high-altitude adaptation in Tibetans.

Proc Natl Acad Sci U S A 2017 04 3;114(16):4189-4194. Epub 2017 Apr 3.

The Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University, China National Engineering Research Center of Ophthalmology and Optometry, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health, Wenzhou 325027, China

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http://dx.doi.org/10.1073/pnas.1617042114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402460PMC
April 2017

The Genetic Architecture of Gene Expression in Peripheral Blood.

Am J Hum Genet 2017 02 5;100(2):228-237. Epub 2017 Jan 5.

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297163053
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http://dx.doi.org/10.1016/j.ajhg.2016.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294670PMC
February 2017

Genetics and educational attainment.

NPJ Sci Learn 2017 1;2. Epub 2017 Feb 1.

2Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072 Australia.

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http://dx.doi.org/10.1038/s41539-017-0005-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220209PMC
February 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.

Genome Biol 2016 12 12;17(1):255. Epub 2016 Dec 12.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13059-016-1119-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151130PMC
December 2016

Epigenetic Signatures of Cigarette Smoking.

Circ Cardiovasc Genet 2016 Oct 20;9(5):436-447. Epub 2016 Sep 20.

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267325PMC
October 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits.

Sci Rep 2016 09 8;6:32894. Epub 2016 Sep 8.

Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/srep32894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015118PMC
September 2016

52 Genetic Loci Influencing Myocardial Mass.

Authors:
Pim van der Harst Jessica van Setten Niek Verweij Georg Vogler Lude Franke Matthew T Maurano Xinchen Wang Irene Mateo Leach Mark Eijgelsheim Nona Sotoodehnia Caroline Hayward Rossella Sorice Osorio Meirelles Leo-Pekka Lyytikäinen Ozren Polašek Toshiko Tanaka Dan E Arking Sheila Ulivi Stella Trompet Martina Müller-Nurasyid Albert V Smith Marcus Dörr Kathleen F Kerr Jared W Magnani Fabiola Del Greco M Weihua Zhang Ilja M Nolte Claudia T Silva Sandosh Padmanabhan Vinicius Tragante Tõnu Esko Gonçalo R Abecasis Michiel E Adriaens Karl Andersen Phil Barnett Joshua C Bis Rolf Bodmer Brendan M Buckley Harry Campbell Megan V Cannon Aravinda Chakravarti Lin Y Chen Alessandro Delitala Richard B Devereux Pieter A Doevendans Anna F Dominiczak Luigi Ferrucci Ian Ford Christian Gieger Tamara B Harris Eric Haugen Matthias Heinig Dena G Hernandez Hans L Hillege Joel N Hirschhorn Albert Hofman Norbert Hubner Shih-Jen Hwang Annamaria Iorio Mika Kähönen Manolis Kellis Ivana Kolcic Ishminder K Kooner Jaspal S Kooner Jan A Kors Edward G Lakatta Kasper Lage Lenore J Launer Daniel Levy Alicia Lundby Peter W Macfarlane Dalit May Thomas Meitinger Andres Metspalu Stefania Nappo Silvia Naitza Shane Neph Alex S Nord Teresa Nutile Peter M Okin Jesper V Olsen Ben A Oostra Josef M Penninger Len A Pennacchio Tune H Pers Siegfried Perz Annette Peters Yigal M Pinto Arne Pfeufer Maria Grazia Pilia Peter P Pramstaller Bram P Prins Olli T Raitakari Soumya Raychaudhuri Ken M Rice Elizabeth J Rossin Jerome I Rotter Sebastian Schafer David Schlessinger Carsten O Schmidt Jobanpreet Sehmi Herman H W Silljé Gianfranco Sinagra Moritz F Sinner Kamil Slowikowski Elsayed Z Soliman Timothy D Spector Wilko Spiering John A Stamatoyannopoulos Ronald P Stolk Konstantin Strauch Sian-Tsung Tan Kirill V Tarasov Bosco Trinh Andre G Uitterlinden Malou van den Boogaard Cornelia M van Duijn Wiek H van Gilst Jorma S Viikari Peter M Visscher Veronique Vitart Uwe Völker Melanie Waldenberger Christian X Weichenberger Harm-Jan Westra Cisca Wijmenga Bruce H Wolffenbuttel Jian Yang Connie R Bezzina Patricia B Munroe Harold Snieder Alan F Wright Igor Rudan Laurie A Boyer Folkert W Asselbergs Dirk J van Veldhuisen Bruno H Stricker Bruce M Psaty Marina Ciullo Serena Sanna Terho Lehtimäki James F Wilson Stefania Bandinelli Alvaro Alonso Paolo Gasparini J Wouter Jukema Stefan Kääb Vilmundur Gudnason Stephan B Felix Susan R Heckbert Rudolf A de Boer Christopher Newton-Cheh Andrew A Hicks John C Chambers Yalda Jamshidi Axel Visel Vincent M Christoffels Aaron Isaacs Nilesh J Samani Paul I W de Bakker

J Am Coll Cardiol 2016 09;68(13):1435-1448

Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jacc.2016.07.729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478167PMC
September 2016

GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs.

Proc Natl Acad Sci U S A 2016 08 25;113(32):E4579-80. Epub 2016 Jul 25.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia; The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane, QLD 4102, Australia;

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http://dx.doi.org/10.1073/pnas.1602743113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987770PMC
August 2016

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations.

Nat Genet 2016 07 23;48(7):718-24. Epub 2016 May 23.

Department of Primary Industries, Biosciences Research Division, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/ng.3577DOI Listing
July 2016

Genetic pleiotropy in complex traits and diseases: implications for genomic medicine.

Genome Med 2016 07 19;8(1):78. Epub 2016 Jul 19.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1186/s13073-016-0332-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952057PMC
July 2016

A stroke of insight from genetics.

Lancet Neurol 2016 06 7;15(7):653-654. Epub 2016 Apr 7.

Brain Center Rudolf Magnus, Department of Neurology, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1016/S1474-4422(16)30028-XDOI Listing
June 2016

A plethora of pleiotropy across complex traits.

Nat Genet 2016 06;48(7):707-8

Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.3604DOI Listing
June 2016

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

JAMA Psychiatry 2016 05;73(5):497-505

Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785705PMC
May 2016

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets.

Nat Genet 2016 05 28;48(5):481-7. Epub 2016 Mar 28.

Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.3538DOI Listing
May 2016

Genome-wide association study identifies 74 loci associated with educational attainment.

Authors:
Aysu Okbay Jonathan P Beauchamp Mark Alan Fontana James J Lee Tune H Pers Cornelius A Rietveld Patrick Turley Guo-Bo Chen Valur Emilsson S Fleur W Meddens Sven Oskarsson Joseph K Pickrell Kevin Thom Pascal Timshel Ronald de Vlaming Abdel Abdellaoui Tarunveer S Ahluwalia Jonas Bacelis Clemens Baumbach Gyda Bjornsdottir Johannes H Brandsma Maria Pina Concas Jaime Derringer Nicholas A Furlotte Tessel E Galesloot Giorgia Girotto Richa Gupta Leanne M Hall Sarah E Harris Edith Hofer Momoko Horikoshi Jennifer E Huffman Kadri Kaasik Ioanna P Kalafati Robert Karlsson Augustine Kong Jari Lahti Sven J van der Lee Christiaan deLeeuw Penelope A Lind Karl-Oskar Lindgren Tian Liu Massimo Mangino Jonathan Marten Evelin Mihailov Michael B Miller Peter J van der Most Christopher Oldmeadow Antony Payton Natalia Pervjakova Wouter J Peyrot Yong Qian Olli Raitakari Rico Rueedi Erika Salvi Börge Schmidt Katharina E Schraut Jianxin Shi Albert V Smith Raymond A Poot Beate St Pourcain Alexander Teumer Gudmar Thorleifsson Niek Verweij Dragana Vuckovic Juergen Wellmann Harm-Jan Westra Jingyun Yang Wei Zhao Zhihong Zhu Behrooz Z Alizadeh Najaf Amin Andrew Bakshi Sebastian E Baumeister Ginevra Biino Klaus Bønnelykke Patricia A Boyle Harry Campbell Francesco P Cappuccio Gail Davies Jan-Emmanuel De Neve Panos Deloukas Ilja Demuth Jun Ding Peter Eibich Lewin Eisele Niina Eklund David M Evans Jessica D Faul Mary F Feitosa Andreas J Forstner Ilaria Gandin Bjarni Gunnarsson Bjarni V Halldórsson Tamara B Harris Andrew C Heath Lynne J Hocking Elizabeth G Holliday Georg Homuth Michael A Horan Jouke-Jan Hottenga Philip L de Jager Peter K Joshi Astanand Jugessur Marika A Kaakinen Mika Kähönen Stavroula Kanoni Liisa Keltigangas-Järvinen Lambertus A L M Kiemeney Ivana Kolcic Seppo Koskinen Aldi T Kraja Martin Kroh Zoltan Kutalik Antti Latvala Lenore J Launer Maël P Lebreton Douglas F Levinson Paul Lichtenstein Peter Lichtner David C M Liewald Anu Loukola Pamela A Madden Reedik Mägi Tomi Mäki-Opas Riccardo E Marioni Pedro Marques-Vidal Gerardus A Meddens George McMahon Christa Meisinger Thomas Meitinger Yusplitri Milaneschi Lili Milani Grant W Montgomery Ronny Myhre Christopher P Nelson Dale R Nyholt William E R Ollier Aarno Palotie Lavinia Paternoster Nancy L Pedersen Katja E Petrovic David J Porteous Katri Räikkönen Susan M Ring Antonietta Robino Olga Rostapshova Igor Rudan Aldo Rustichini Veikko Salomaa Alan R Sanders Antti-Pekka Sarin Helena Schmidt Rodney J Scott Blair H Smith Jennifer A Smith Jan A Staessen Elisabeth Steinhagen-Thiessen Konstantin Strauch Antonio Terracciano Martin D Tobin Sheila Ulivi Simona Vaccargiu Lydia Quaye Frank J A van Rooij Cristina Venturini Anna A E Vinkhuyzen Uwe Völker Henry Völzke Judith M Vonk Diego Vozzi Johannes Waage Erin B Ware Gonneke Willemsen John R Attia David A Bennett Klaus Berger Lars Bertram Hans Bisgaard Dorret I Boomsma Ingrid B Borecki Ute Bültmann Christopher F Chabris Francesco Cucca Daniele Cusi Ian J Deary George V Dedoussis Cornelia M van Duijn Johan G Eriksson Barbara Franke Lude Franke Paolo Gasparini Pablo V Gejman Christian Gieger Hans-Jörgen Grabe Jacob Gratten Patrick J F Groenen Vilmundur Gudnason Pim van der Harst Caroline Hayward David A Hinds Wolfgang Hoffmann Elina Hyppönen William G Iacono Bo Jacobsson Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Terho Lehtimäki Steven F Lehrer Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Neil Pendleton Brenda W J H Penninx Markus Perola Nicola Pirastu Mario Pirastu Ozren Polasek Danielle Posthuma Christine Power Michael A Province Nilesh J Samani David Schlessinger Reinhold Schmidt Thorkild I A Sørensen Tim D Spector Kari Stefansson Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier Joyce Y Tung André G Uitterlinden Veronique Vitart Peter Vollenweider David R Weir James F Wilson Alan F Wright Dalton C Conley Robert F Krueger George Davey Smith Albert Hofman David I Laibson Sarah E Medland Michelle N Meyer Jian Yang Magnus Johannesson Peter M Visscher Tõnu Esko Philipp D Koellinger David Cesarini Daniel J Benjamin

Nature 2016 05 11;533(7604):539-42. Epub 2016 May 11.

Center for Economic and Social Research, University of Southern California, Los Angeles, California 90089-3332, USA.

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http://dx.doi.org/10.1038/nature17671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883595PMC
May 2016

Authors' Response to Kaufman and Muntaner.

Int J Epidemiol 2016 04 27;45(2):578-9. Epub 2016 Mar 27.

Queensland Brain Institute, University of Queensland Diamantina Institute, Woolloongabba, QLD, Australia.

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http://dx.doi.org/10.1093/ije/dyw020DOI Listing
April 2016

Human Complex Trait Genetics in the 21st Century.

Authors:
Peter M Visscher

Genetics 2016 Feb;202(2):377-9

Queensland Brain Institute, University of Queensland, Brisbane, Queensland 4072, Australia

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http://dx.doi.org/10.1534/genetics.115.180513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788221PMC
February 2016