Publications by authors named "Peter M Visscher"

99Publications

Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock.

PLoS Genet 2020 Sep 14;16(9):e1008780. Epub 2020 Sep 14.

Institute for Molecular Bioscience, University of Queensland, St. Lucia, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1008780DOI Listing
September 2020

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations.

Nat Commun 2020 07 31;11(1):3865. Epub 2020 Jul 31.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1038/s41467-020-17719-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395791PMC
July 2020

Musings on Visscher et al. (2006).

Authors:
Peter M Visscher

Twin Res Hum Genet 2020 04 19;23(2):107-108. Epub 2020 May 19.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1017/thg.2020.21DOI Listing
April 2020

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Authors:
Sonia Shah Albert Henry Carolina Roselli Honghuang Lin Garðar Sveinbjörnsson Ghazaleh Fatemifar Åsa K Hedman Jemma B Wilk Michael P Morley Mark D Chaffin Anna Helgadottir Niek Verweij Abbas Dehghan Peter Almgren Charlotte Andersson Krishna G Aragam Johan Ärnlöv Joshua D Backman Mary L Biggs Heather L Bloom Jeffrey Brandimarto Michael R Brown Leonard Buckbinder David J Carey Daniel I Chasman Xing Chen Xu Chen Jonathan Chung William Chutkow James P Cook Graciela E Delgado Spiros Denaxas Alexander S Doney Marcus Dörr Samuel C Dudley Michael E Dunn Gunnar Engström Tõnu Esko Stephan B Felix Chris Finan Ian Ford Mohsen Ghanbari Sahar Ghasemi Vilmantas Giedraitis Franco Giulianini John S Gottdiener Stefan Gross Daníel F Guðbjartsson Rebecca Gutmann Christopher M Haggerty Pim van der Harst Craig L Hyde Erik Ingelsson J Wouter Jukema Maryam Kavousi Kay-Tee Khaw Marcus E Kleber Lars Køber Andrea Koekemoer Claudia Langenberg Lars Lind Cecilia M Lindgren Barry London Luca A Lotta Ruth C Lovering Jian'an Luan Patrik Magnusson Anubha Mahajan Kenneth B Margulies Winfried März Olle Melander Ify R Mordi Thomas Morgan Andrew D Morris Andrew P Morris Alanna C Morrison Michael W Nagle Christopher P Nelson Alexander Niessner Teemu Niiranen Michelle L O'Donoghue Anjali T Owens Colin N A Palmer Helen M Parry Markus Perola Eliana Portilla-Fernandez Bruce M Psaty Kenneth M Rice Paul M Ridker Simon P R Romaine Jerome I Rotter Perttu Salo Veikko Salomaa Jessica van Setten Alaa A Shalaby Diane T Smelser Nicholas L Smith Steen Stender David J Stott Per Svensson Mari-Liis Tammesoo Kent D Taylor Maris Teder-Laving Alexander Teumer Guðmundur Thorgeirsson Unnur Thorsteinsdottir Christian Torp-Pedersen Stella Trompet Benoit Tyl Andre G Uitterlinden Abirami Veluchamy Uwe Völker Adriaan A Voors Xiaosong Wang Nicholas J Wareham Dawn Waterworth Peter E Weeke Raul Weiss Kerri L Wiggins Heming Xing Laura M Yerges-Armstrong Bing Yu Faiez Zannad Jing Hua Zhao Harry Hemingway Nilesh J Samani John J V McMurray Jian Yang Peter M Visscher Christopher Newton-Cheh Anders Malarstig Hilma Holm Steven A Lubitz Naveed Sattar Michael V Holmes Thomas P Cappola Folkert W Asselbergs Aroon D Hingorani Karoline Kuchenbaecker Patrick T Ellinor Chim C Lang Kari Stefansson J Gustav Smith Ramachandran S Vasan Daniel I Swerdlow R Thomas Lumbers

Nat Commun 2020 01 9;11(1):163. Epub 2020 Jan 9.

British Heart Foundation Research Accelerator, University College London, London, UK.

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http://dx.doi.org/10.1038/s41467-019-13690-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952380PMC
January 2020

A resource-efficient tool for mixed model association analysis of large-scale data.

Nat Genet 2019 12 25;51(12):1749-1755. Epub 2019 Nov 25.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/s41588-019-0530-8DOI Listing
December 2019

Genetic correlates of social stratification in Great Britain.

Nat Hum Behav 2019 12 21;3(12):1332-1342. Epub 2019 Oct 21.

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1038/s41562-019-0757-5DOI Listing
December 2019

Extreme inbreeding in a European ancestry sample from the contemporary UK population.

Nat Commun 2019 09 3;10(1):3719. Epub 2019 Sep 3.

Institute for Molecular Bioscience, The University of Queensland, QLD 4072, Brisbane, Australia.

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http://dx.doi.org/10.1038/s41467-019-11724-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722066PMC
September 2019

"Arte et Labore"-A Blackburn Rovers fan's legacy in human complex trait genetics.

J Anim Breed Genet 2019 Jul;136(4):273-278

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/jbg.12384DOI Listing
July 2019

OSCA: a tool for omic-data-based complex trait analysis.

Genome Biol 2019 05 28;20(1):107. Epub 2019 May 28.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.

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http://dx.doi.org/10.1186/s13059-019-1718-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537380PMC
May 2019

Tissue-specific sex differences in human gene expression.

Hum Mol Genet 2019 09;28(17):2976-2986

Institute for Molecular Bioscience.

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http://dx.doi.org/10.1093/hmg/ddz090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736104PMC
September 2019

Genome-wide association study of medication-use and associated disease in the UK Biobank.

Nat Commun 2019 04 23;10(1):1891. Epub 2019 Apr 23.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-019-09572-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478889PMC
April 2019

Complex Trait Prediction from Genome Data: Contrasting EBV in Livestock to PRS in Humans: Genomic Prediction.

Genetics 2019 04;211(4):1131-1141

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4067, Australia.

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http://dx.doi.org/10.1534/genetics.119.301859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456317PMC
April 2019

From R.A. Fisher's 1918 Paper to GWAS a Century Later.

Genetics 2019 04;211(4):1125-1130

Centre for AgriBioscience, Department of Economic Development, Jobs, Transport and Resources, Bundoora, Victoria, Australia 3083.

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http://dx.doi.org/10.1534/genetics.118.301594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456325PMC
April 2019

Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes.

Nat Genet 2019 02 14;51(2):327-334. Epub 2019 Jan 14.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0313-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358510PMC
February 2019

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.

Nat Commun 2018 12 20;9(1):5407. Epub 2018 Dec 20.

Institute for Molecular Bioscience, University of Queensland, Queensland, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-07862-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302097PMC
December 2018

Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness.

Nat Commun 2018 11 20;9(1):4953. Epub 2018 Nov 20.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-07400-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244080PMC
November 2018

Epigenetic signatures of starting and stopping smoking.

EBioMedicine 2018 Nov 30;37:214-220. Epub 2018 Oct 30.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.10.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286188PMC
November 2018

Assortative mating on complex traits revisited: Double first cousins and the X-chromosome.

Theor Popul Biol 2018 12 11;124:51-60. Epub 2018 Oct 11.

Institute for Molecular Bioscience, The University of Queensland, Brisbane 4072, Australia; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.

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http://dx.doi.org/10.1016/j.tpb.2018.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296780PMC
December 2018

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

Nat Genet 2018 07 23;50(8):1112-1121. Epub 2018 Jul 23.

National Bureau of Economic Research, Cambridge, MA, USA.

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http://www.nature.com/articles/s41588-018-0147-3
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http://dx.doi.org/10.1038/s41588-018-0147-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393768PMC
July 2018

Misestimation of heritability and prediction accuracy of male-pattern baldness.

Nat Commun 2018 06 29;9(1):2537. Epub 2018 Jun 29.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04807-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026149PMC
June 2018

Leveraging GWAS for complex traits to detect signatures of natural selection in humans.

Curr Opin Genet Dev 2018 12 16;53:9-14. Epub 2018 Jun 16.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2018.05.012DOI Listing
December 2018

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model.

Cell 2018 06;173(7):1573-1580

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia; Queensland Brain Institute, The University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.cell.2018.05.051DOI Listing
June 2018

Global genetic differentiation of complex traits shaped by natural selection in humans.

Nat Commun 2018 05 14;9(1):1865. Epub 2018 May 14.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951811PMC
May 2018

Global genetic differentiation of complex traits shaped by natural selection in humans.

Nat Commun 2018 05 14;9(1):1865. Epub 2018 May 14.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-018-04191-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951811PMC
May 2018

A multi-trait Bayesian method for mapping QTL and genomic prediction.

Genet Sel Evol 2018 03 24;50(1):10. Epub 2018 Mar 24.

Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, 3052, Australia.

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http://dx.doi.org/10.1186/s12711-018-0377-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866527PMC
March 2018

Reply to Kardos et al.: Estimation of inbreeding depression from SNP data.

Proc Natl Acad Sci U S A 2018 03 21;115(11):E2494-E2495. Epub 2018 Feb 21.

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia;

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http://dx.doi.org/10.1073/pnas.1718598115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856540PMC
March 2018

Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio.

Genetics 2018 04 2;208(4):1397-1408. Epub 2018 Feb 2.

Institute for Molecular Bioscience, University of Queensland, Brisbane 4072, Australia.

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http://dx.doi.org/10.1534/genetics.117.300360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887138PMC
April 2018

Causal associations between risk factors and common diseases inferred from GWAS summary data.

Nat Commun 2018 01 15;9(1):224. Epub 2018 Jan 15.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-017-02317-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768719PMC
January 2018

Evidence of directional and stabilizing selection in contemporary humans.

Proc Natl Acad Sci U S A 2018 01 18;115(1):151-156. Epub 2017 Dec 18.

Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia;

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http://dx.doi.org/10.1073/pnas.1707227114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776788PMC
January 2018

Challenges in understanding common disease.

Authors:
Peter M Visscher

Genome Med 2017 12 18;9(1):112. Epub 2017 Dec 18.

Institute for Molecular Bioscience and Queensland Brain Institute, University of Queensland, St Lucia, QLD, 4072, Australia.

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http://dx.doi.org/10.1186/s13073-017-0506-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733735PMC
December 2017

Gene networks associated with non-syndromic intellectual disability.

J Neurogenet 2018 03 4;32(1):6-14. Epub 2017 Dec 4.

a Mater Research Institute, The University of Queensland , Woolloongabba , Australia.

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http://dx.doi.org/10.1080/01677063.2017.1404058DOI Listing
March 2018

Commentary: Fisher 1918: the foundation of the genetics and analysis of complex traits.

Int J Epidemiol 2019 02 17;48(1):10-12. Epub 2017 Jul 17.

Institute for Molecular Bioscience.

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http://dx.doi.org/10.1093/ije/dyx129DOI Listing
February 2019

Testing Two Evolutionary Theories of Human Aging with DNA Methylation Data.

Genetics 2017 12 30;207(4):1547-1560. Epub 2017 Aug 30.

Department of Human Genetics, Emory University School of Medicine, Emory University, Atlanta, Georgia 30322.

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http://dx.doi.org/10.1534/genetics.117.300217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714465PMC
December 2017

Concepts, estimation and interpretation of SNP-based heritability.

Nat Genet 2017 Aug;49(9):1304-1310

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.3941DOI Listing
August 2017

Detection and quantification of inbreeding depression for complex traits from SNP data.

Proc Natl Acad Sci U S A 2017 08 26;114(32):8602-8607. Epub 2017 Jul 26.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia;

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http://dx.doi.org/10.1073/pnas.1621096114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558994PMC
August 2017

10 Years of GWAS Discovery: Biology, Function, and Translation.

Am J Hum Genet 2017 Jul;101(1):5-22

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1016/j.ajhg.2017.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501872PMC
July 2017

Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing data.

Genome Biol 2017 05 16;18(1):86. Epub 2017 May 16.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://genomebiology.biomedcentral.com/articles/10.1186/s130
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http://dx.doi.org/10.1186/s13059-017-1216-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432979PMC
May 2017

Inference on the Genetic Basis of Eye and Skin Color in an Admixed Population via Bayesian Linear Mixed Models.

Genetics 2017 06 4;206(2):1113-1126. Epub 2017 Apr 4.

Institute for Molecular Bioscience, University of Queensland, St. Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1534/genetics.116.193383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499166PMC
June 2017

Genetic signatures of high-altitude adaptation in Tibetans.

Proc Natl Acad Sci U S A 2017 04 3;114(16):4189-4194. Epub 2017 Apr 3.

The Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University, China National Engineering Research Center of Ophthalmology and Optometry, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health, Wenzhou 325027, China

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http://dx.doi.org/10.1073/pnas.1617042114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402460PMC
April 2017

Genetic Stratification to Identify Risk Groups for Alzheimer's Disease.

J Alzheimers Dis 2017 ;57(1):275-283

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.3233/JAD-161070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345653PMC
February 2018

Genetics and educational attainment.

NPJ Sci Learn 2017 1;2. Epub 2017 Feb 1.

2Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072 Australia.

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http://dx.doi.org/10.1038/s41539-017-0005-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220209PMC
February 2017

The Genetic Architecture of Gene Expression in Peripheral Blood.

Am J Hum Genet 2017 02 5;100(2):228-237. Epub 2017 Jan 5.

Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia; Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297163053
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http://dx.doi.org/10.1016/j.ajhg.2016.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294670PMC
February 2017