Peter M Rothwell

Peter M Rothwell

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Peter M Rothwell

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Reliability, reproducibility and validity of dynamic cerebral autoregulation in a large cohort with transient ischaemic attack or minor stroke.

Physiol Meas 2020 Aug 7. Epub 2020 Aug 7.

Nuffield Department of Clinical Neurosciences, University of Oxford, Wolfson Centre for Prevention of Stroke and Dementia, Oxford, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

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http://dx.doi.org/10.1088/1361-6579/abad49DOI Listing
August 2020

Extended short-term follow-up for a trial of treatment of unruptured arteriovenous malformations.

Authors:
Peter M Rothwell

Lancet Neurol 2020 07;19(7):558-559

Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(20)30178-2DOI Listing
July 2020

Prognosis of Cryptogenic Stroke With Patent Foramen Ovale at Older Ages and Implications for Trials: A Population-Based Study and Systematic Review.

JAMA Neurol 2020 Jul 6. Epub 2020 Jul 6.

Wolfson Centre for Prevention of Stroke and Dementia, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2020.1948DOI Listing
July 2020

Antiplatelet Treatment to Prevent Early Recurrent Stroke.

Authors:
Peter M Rothwell

N Engl J Med 2020 07;383(3):276-278

From the Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1056/NEJMe2018927DOI Listing
July 2020

Blood Pressure-Lowering Profiles and Clinical Effects of Angiotensin Receptor Blockers Versus Calcium Channel Blockers.

Hypertension 2020 Jun 27;75(6):1584-1592. Epub 2020 Apr 27.

Department of Cardiology (S.E.K., E.B.), Oslo University Hospital Ullevaal, Oslo, Norway.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14443DOI Listing
June 2020

Weights for ordinal analyses of the modified Rankin Scale in stroke trials: A population-based cohort study.

EClinicalMedicine 2020 Jun 15;23:100415. Epub 2020 Jun 15.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1016/j.eclinm.2020.100415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300241PMC
June 2020

Refining prediction of major bleeding on antiplatelet treatment after transient ischaemic attack or ischaemic stroke.

Eur Stroke J 2020 Jun 19;5(2):130-137. Epub 2020 Jan 19.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, the Netherlands.

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http://dx.doi.org/10.1177/2396987319898064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309362PMC
June 2020

The case for statin use to reduce perioperative adverse cardiovascular and cerebrovascular events.

Br J Anaesth 2020 May 25;124(5):525-534. Epub 2020 Feb 25.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.bja.2020.01.010DOI Listing
May 2020

Trends in Stroke Incidence in High-Income Countries in the 21st Century: Population-Based Study and Systematic Review.

Stroke 2020 May 25;51(5):1372-1380. Epub 2020 Mar 25.

From the Nuffield Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.119.028484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185053PMC
May 2020

Prevalence, predictors, and prognosis of symptomatic intracranial stenosis in patients with transient ischaemic attack or minor stroke: a population-based cohort study.

Lancet Neurol 2020 05;19(5):413-421

Wolfson Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(20)30079-XDOI Listing
May 2020

Prognosis of Asymptomatic Intracranial Stenosis in Patients With Transient Ischemic Attack and Minor Stroke.

JAMA Neurol 2020 May 26. Epub 2020 May 26.

Wolfson Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1001/jamaneurol.2020.1326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251503PMC
May 2020

Blood pressure and the brain: the neurology of hypertension.

Pract Neurol 2020 Apr 26;20(2):100-108. Epub 2019 Sep 26.

Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, Oxfordshire, UK.

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http://dx.doi.org/10.1136/practneurol-2019-002269DOI Listing
April 2020

APOE-ε4 Genotype and Dementia Before and After Transient Ischemic Attack and Stroke: Population-Based Cohort Study.

Stroke 2020 03 18;51(3):751-758. Epub 2020 Feb 18.

From the Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital and the University of Oxford, UK.

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http://dx.doi.org/10.1161/STROKEAHA.119.026927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224982PMC
March 2020

Global Stroke Statistics 2019.

Int J Stroke 2020 Mar 9:1747493020909545. Epub 2020 Mar 9.

Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1177/1747493020909545DOI Listing
March 2020

Generating comparative evidence on new drugs and devices after approval.

Lancet 2020 03;395(10228):998-1010

Department of Health Policy, London School of Economics and Political Science, London, UK.

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http://dx.doi.org/10.1016/S0140-6736(19)33177-0DOI Listing
March 2020

Temporal trends in the accuracy of hospital diagnostic coding for identifying acute stroke: A population-based study.

Eur Stroke J 2020 Mar 14;5(1):26-35. Epub 2019 Oct 14.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/2396987319881017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092737PMC
March 2020

Re: Author response regarding the Letter to the Editor about the article 'Temporal trends in the accuracy of hospital diagnostic coding for identifying acute stroke: A population-based study'. 2019 Oct 14. DOI: 10.1177/2396987319881017.

Eur Stroke J 2020 Mar 22;5(1):102-103. Epub 2019 Dec 22.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/2396987319896679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092735PMC
March 2020

Prevention and treatment of stroke in patients with chronic kidney disease: an overview of evidence and current guidelines.

Kidney Int 2020 02 18;97(2):266-278. Epub 2019 Oct 18.

Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/j.kint.2019.09.024DOI Listing
February 2020

Confounding of Cerebral Blood Flow Velocity by Blood Pressure During Breath Holding or Hyperventilation in Transient Ischemic Attack or Stroke.

Stroke 2020 02 30;51(2):468-474. Epub 2019 Dec 30.

From the Department of Clinical Neuroscience, Wolfson Centre for Prevention of Stroke and Dementia, University of Oxford, United Kingdom (A.J.S.W., S.M., L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.119.027829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004447PMC
February 2020

Proteinuria as an independent predictor of stroke: Systematic review and meta-analysis.

Int J Stroke 2020 01 14;15(1):29-38. Epub 2020 Jan 14.

Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/1747493019895206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003151PMC
January 2020

Essen Risk Score in Prediction of Myocardial Infarction After Transient Ischemic Attack or Ischemic Stroke Without Prior Coronary Artery Disease.

Stroke 2019 12 22;50(12):3393-3399. Epub 2019 Oct 22.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, United Kingdom (M.B., L.L., S.L., N.G.L., M.M.K., L.S., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025831DOI Listing
December 2019

Automated lesion segmentation with BIANCA: Impact of population-level features, classification algorithm and locally adaptive thresholding.

Neuroimage 2019 11 31;202:116056. Epub 2019 Jul 31.

Wellcome Centre for Integrative Neuroimaging, Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2019.116056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996003PMC
November 2019

Does Chronic Kidney Disease Predict Stroke Risk Independent of Blood Pressure?: A Systematic Review and Meta-Regression.

Stroke 2019 11 9;50(11):3085-3092. Epub 2019 Oct 9.

From the Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.119.025442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824504PMC
November 2019

Costs of bleeding on long-term antiplatelet treatment without routine co-prescription of proton-pump inhibitors.

Int J Stroke 2019 Sep 30:1747493019879658. Epub 2019 Sep 30.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/1747493019879658DOI Listing
September 2019

Effect of coexisting vascular disease on long-term risk of recurrent events after TIA or stroke.

Neurology 2019 08 23;93(7):e695-e707. Epub 2019 Jul 23.

From the Centre for Prevention of Stroke and Dementia (M.B., L.L., S.L., N.G.L., M.M.K., L.S., P.M.R.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, UK; and Service de Neurologie (M.B., E.T.), CHU Caen Normandie, UNICAEN, Normandie Université, INSERM U1237, Caen, France.

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http://dx.doi.org/10.1212/WNL.0000000000007935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715511PMC
August 2019

Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT.

Health Technol Assess 2019 08;23(41):1-30

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.3310/hta23410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717908PMC
August 2019

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Authors:
Duncan Wilson Gareth Ambler Keon-Joo Lee Jae-Sung Lim Masayuki Shiozawa Masatoshi Koga Linxin Li Caroline Lovelock Hugues Chabriat Michael Hennerici Yuen Kwun Wong Henry Ka Fung Mak Luis Prats-Sánchez Alejandro Martínez-Domeño Shigeru Inamura Kazuhisa Yoshifuji Ethem Murat Arsava Solveig Horstmann Jan Purrucker Bonnie Yin Ka Lam Adrian Wong Young Dae Kim Tae-Jin Song Maarten Schrooten Robin Lemmens Sebastian Eppinger Thomas Gattringer Ender Uysal Zeynep Tanriverdi Natan M Bornstein Einor Ben Assayag Hen Hallevi Jun Tanaka Hideo Hara Shelagh B Coutts Lisa Hert Alexandros Polymeris David J Seiffge Philippe Lyrer Ale Algra Jaap Kappelle Rustam Al-Shahi Salman Hans R Jäger Gregory Y H Lip Heinrich P Mattle Leonidas D Panos Jean-Louis Mas Laurence Legrand Christopher Karayiannis Thanh Phan Sarah Gunkel Nicolas Christ Jill Abrigo Thomas Leung Winnie Chu Francesca Chappell Stephen Makin Derek Hayden David J Williams M Eline Kooi Dianne H K van Dam-Nolen Carmen Barbato Simone Browning Kim Wiegertjes Anil M Tuladhar Noortje Maaijwee Christine Guevarra Chathuri Yatawara Anne-Marie Mendyk Christine Delmaire Sebastian Köhler Robert van Oostenbrugge Ying Zhou Chao Xu Saima Hilal Bibek Gyanwali Christopher Chen Min Lou Julie Staals Régis Bordet Nagaendran Kandiah Frank-Erik de Leeuw Robert Simister Aad van der Lugt Peter J Kelly Joanna M Wardlaw Yannie Soo Felix Fluri Velandai Srikanth David Calvet Simon Jung Vincent I H Kwa Stefan T Engelter Nils Peters Eric E Smith Yusuke Yakushiji Dilek Necioglu Orken Franz Fazekas Vincent Thijs Ji Hoe Heo Vincent Mok Roland Veltkamp Hakan Ay Toshio Imaizumi Beatriz Gomez-Anson Kui Kai Lau Eric Jouvent Peter M Rothwell Kazunori Toyoda Hee-Joon Bae Joan Marti-Fabregas David J Werring

Lancet Neurol 2019 07 23;18(7):653-665. Epub 2019 May 23.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422193019
Publisher Site
http://dx.doi.org/10.1016/S1474-4422(19)30197-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562236PMC
July 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-019-0449-0DOI Listing
July 2019

Age-dependent association of white matter abnormality with cognition after TIA or minor stroke.

Neurology 2019 07 14;93(3):e272-e282. Epub 2019 Jun 14.

From the Centre for Prevention of Stroke and Dementia (G.Z., L.G., S.M., S.T.P., P.M.R.) and Wellcome Centre for Integrative Neuroimaging, FMRIB (G.Z., L.G.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford; and Department of Biomedical, Metabolic and Neural Sciences and Centre for Neurosciences and Neurotechnology (G.Z.), University of Modena and Reggio Emilia, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000007772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656647PMC
July 2019

Sensitivity of Administrative Coding in Identifying Inpatient Acute Strokes Complicating Procedures or Other Diseases in UK Hospitals.

J Am Heart Assoc 2019 07 3;8(14):e012995. Epub 2019 Jul 3.

1 Centre for Prevention of Stroke and Dementia Nuffield Department of Clinical Neuroscience University of Oxford United Kingdom.

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http://dx.doi.org/10.1161/JAHA.119.012995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662118PMC
July 2019

Prognostic value of "tissue-based" definitions of TIA and minor stroke: Population-based study.

Neurology 2019 05 17;92(21):e2455-e2461. Epub 2019 Apr 17.

From the Centre for the Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541432PMC
May 2019

Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study.

Lancet Neurol 2019 03 12;18(3):248-258. Epub 2019 Feb 12.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital and University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S1474-4422(18)30442-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390174PMC
March 2019

Disseminated leptomeningeal tumour mimicking a subarachnoid haemorrhage.

Neuroradiol J 2019 Feb 9;32(1):53-56. Epub 2018 Aug 9.

2 Nuffield Department of Clinical Neuroscience, University of Oxford, UK.

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http://dx.doi.org/10.1177/1971400918793530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327359PMC
February 2019

Genetic variation in is associated with white matter hyperintensities (n = 11,226).

Neurology 2019 02 18;92(8):e749-e757. Epub 2019 Jan 18.

From the Department of Clinical Neurosciences, Stroke Research Group (M.T., D.J.T., I.D.C., D.M.L.F., A.O.O., L.R.-J., H.S.M.), University of Cambridge, UK; Department of Cerebrovascular Diseases (G.B.), Fondazione IRCCS Istituto Neurologico "Carlo Besta," Milan, Italy; Institute for Stroke and Dementia Research (M.D.), Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich; German Center for Neurodegenerative Diseases (DZNE) and Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND) (R.L.), KU Leuven-University of Leuven; Department of Neurology (R.L.), University Hospitals Leuven; Laboratory of Neurobiology (R.L.), VIB Center for Brain and Disease Research, Leuven, Belgium; Center for Human Genetic Research (J.R.) and Division of Neurocritical Care and Emergency Neurology (J.R.) and J. Philip Kistler Stroke Research Center (J.R., N.S.R.), Department of Neurology, Massachusetts General Hospital, Boston; Nuffield Department of Clinical Neurosciences (Clinical Neurology), Stroke Prevention Research Unit (P.M.R.), University of Oxford; Centre for Clinical Brain Sciences and Institute for Genetics and Molecular Medicine (C.L.M.S.), University of Edinburgh, UK; Stroke Division, Florey Institute of Neuroscience and Mental Health (V.T.), University of Melbourne; and Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000006952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396967PMC
February 2019

Modelling the distribution of white matter hyperintensities due to ageing on MRI images using Bayesian inference.

Neuroimage 2019 01 22;185:434-445. Epub 2018 Oct 22.

Oxford Centre for Functional MRI of Brain (FMRIB), Wellcome Centre for Integrative NeuroImaging, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183201
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2018.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299259PMC
January 2019

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Authors:
Ganesh Chauhan Hieab H H Adams Claudia L Satizabal Joshua C Bis Alexander Teumer Muralidharan Sargurupremraj Edith Hofer Stella Trompet Saima Hilal Albert Vernon Smith Xueqiu Jian Rainer Malik Matthew Traylor Sara L Pulit Philippe Amouyel Bernard Mazoyer Yi-Cheng Zhu Sara Kaffashian Sabrina Schilling Gary W Beecham Thomas J Montine Gerard D Schellenberg Olafur Kjartansson Vilmundur Guðnason David S Knopman Michael E Griswold B Gwen Windham Rebecca F Gottesman Thomas H Mosley Reinhold Schmidt Yasaman Saba Helena Schmidt Fumihiko Takeuchi Shuhei Yamaguchi Toru Nabika Norihiro Kato Kumar B Rajan Neelum T Aggarwal Philip L De Jager Denis A Evans Bruce M Psaty Jerome I Rotter Kenneth Rice Oscar L Lopez Jiemin Liao Christopher Chen Ching-Yu Cheng Tien Y Wong Mohammad K Ikram Sven J van der Lee Najaf Amin Vincent Chouraki Anita L DeStefano Hugo J Aparicio Jose R Romero Pauline Maillard Charles DeCarli Joanna M Wardlaw Maria Del C Valdés Hernández Michelle Luciano David Liewald Ian J Deary John M Starr Mark E Bastin Susana Muñoz Maniega P Eline Slagboom Marian Beekman Joris Deelen Hae-Won Uh Robin Lemmens Henry Brodaty Margaret J Wright David Ames Giorgio B Boncoraglio Jemma C Hopewell Ashley H Beecham Susan H Blanton Clinton B Wright Ralph L Sacco Wei Wen Anbupalam Thalamuthu Nicola J Armstrong Elizabeth Chong Peter R Schofield John B Kwok Jeroen van der Grond David J Stott Ian Ford J Wouter Jukema Meike W Vernooij Albert Hofman André G Uitterlinden Aad van der Lugt Katharina Wittfeld Hans J Grabe Norbert Hosten Bettina von Sarnowski Uwe Völker Christopher Levi Jordi Jimenez-Conde Pankaj Sharma Cathie L M Sudlow Jonathan Rosand Daniel Woo John W Cole James F Meschia Agnieszka Slowik Vincent Thijs Arne Lindgren Olle Melander Raji P Grewal Tatjana Rundek Kathy Rexrode Peter M Rothwell Donna K Arnett Christina Jern Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Quenna Wong Braxton D Mitchell Stephen S Rich Patrick F McArdle Mirjam I Geerlings Yolanda van der Graaf Paul I W de Bakker Folkert W Asselbergs Velandai Srikanth Russell Thomson Rebekah McWhirter Chris Moran Michele Callisaya Thanh Phan Loes C A Rutten-Jacobs Steve Bevan Christophe Tzourio Karen A Mather Perminder S Sachdev Cornelia M van Duijn Bradford B Worrall Martin Dichgans Steven J Kittner Hugh S Markus Mohammad A Ikram Myriam Fornage Lenore J Launer Sudha Seshadri W T Longstreth Stéphanie Debette

Neurology 2019 Jan 16. Epub 2019 Jan 16.

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http://dx.doi.org/10.1212/WNL.0000000000006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369905PMC
January 2019

Ordinal vs dichotomous analyses of modified Rankin Scale, 5-year outcome, and cost of stroke.

Neurology 2018 11 19;91(21):e1951-e1960. Epub 2018 Oct 19.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000006554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260198PMC
November 2018

Time Trends in Atrial Fibrillation-Associated Stroke and Premorbid Anticoagulation.

Stroke 2018 Nov 29:STROKEAHA118022249. Epub 2018 Nov 29.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (G.S.C.Y., L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314508PMC
November 2018

Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke.

Int J Stroke 2018 10 3;13(8):832-839. Epub 2018 Jul 3.

1 Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1177/1747493018784448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424409PMC
October 2018

Long-Term Consequences of Worsened Poststroke Status in Patients With Premorbid Disability.

Stroke 2018 10;49(10):2430-2436

From the Nuffield Department of Clinical Neurosciences, Stroke Prevention Research Unit, University of Oxford, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022416
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http://dx.doi.org/10.1161/STROKEAHA.118.022416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159688PMC
October 2018

Long-Term Premorbid Blood Pressure and Cerebral Small Vessel Disease Burden on Imaging in Transient Ischemic Attack and Ischemic Stroke.

Stroke 2018 09;49(9):2053-2060

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.021578
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http://dx.doi.org/10.1161/STROKEAHA.118.021578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116796PMC
September 2018

Hospital and Institutionalisation Care Costs after Limb and Visceral Ischaemia Benchmarked Against Stroke: Long-Term Results of a Population Based Cohort Study.

Eur J Vasc Endovasc Surg 2018 08 11;56(2):271-281. Epub 2018 Apr 11.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejvs.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105571PMC
August 2018

Long-Term Prognosis of Patients With Transient Ischemic Attack or Stroke and Symptomatic Vascular Disease in Multiple Arterial Beds.

Stroke 2018 07 7;49(7):1639-1646. Epub 2018 Jun 7.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.118.020913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023586PMC
July 2018

Prevalence of patent foramen ovale in cryptogenic transient ischaemic attack and non-disabling stroke at older ages: a population-based study, systematic review, and meta-analysis.

Lancet Neurol 2018 07 7;17(7):609-617. Epub 2018 Jun 7.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S1474-4422(18)30167-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004554PMC
July 2018

Clinical innovation in stroke: getting the simple things right.

Authors:
Peter M Rothwell

Lancet Neurol 2018 06 10;17(6):491-493. Epub 2018 Apr 10.

Centre for Prevention of Stroke and Dementia, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address:

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June 2018

Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review.

Stroke 2018 06 10;49(6):1434-1442. Epub 2018 May 10.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (K.K.L., C.E.L., L.L., M.S., S.G., W.K., P.M.R.)

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http://dx.doi.org/10.1161/STROKEAHA.117.020104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976229PMC
June 2018

Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke.

N Engl J Med 2018 Jun 16;378(23):2182-2190. Epub 2018 May 16.

From Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Neurology and Stroke Center (P.A., P.C.L., L.M.T., J.L., P.-J.T.), and the Department of Cardiology (P.G.S.), Bichat Hospital, INSERM Laboratory for Vascular Translational Science-Unité 1148, Département Hospitalo-Universitaire Fibrose Inflammation Remodelage, Université Paris-Diderot, Sorbonne-Paris Cité, and AP-HP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal Hospital (É.V.), Paris, and Université Lille, Centre Hospitalier Universitaire Lille, Équipe d'Accueil 2694-Santé Publique: Épidémiologie et Qualité des Soins, Lille (J.L.) - all in France; the Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, CA (G.W.A.); the Department of Neurology, Hôtel-Dieu de France, Saint Joseph University, Beirut, Lebanon (H. Abboud); the Stroke Unit, San Camillo Hospital, Rome (S.A.); Ärztliche Leitung der Klinik für Neurologie, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Berlin (H. Audebert), Klinik für Neurologie, Allgemeines Krankenhaus Celle, Celle (W.H.), and the Department of Neurology, Universitäts Medizin Mannheim, Heidelberg University, Heidelberg (M.G.H.) - all in Germany; Shaare Zedek Medical Center, Jerusalem, Israel (N.M.B.); the Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston (L.R.C.); Serviço de Neurologia, Hospital de Santo António-Centro Hospitalar do Porto, Porto (M.C.), and the Department of Neurosciences, Service of Neurology, Hospital Santa Maria, University of Lisbon, Lisbon (J.M.F.) - both in Portugal; the Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia (G.A.D.); the Stroke Unit and Neurology Service, University Hospital José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico (F.G.-R.); the Neurovascular Research Unit and Health Research Board, Stroke Clinical Trials Network Ireland, University College Dublin, Dublin (P.J.K.); the Comprehensive Stroke Center, Palacký University and University Hospital Olomouc (M.K.), and the Department of Nursing, Faculty of Health Science, Palacký University (D.Š), Olomouc, Czech Republic; the Department of Neurology, Kaohsiung Medical University Chung-Ho Memorial Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan (H.-F.L.); the Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona (C.M.), the Stroke Unit, Hospital Universitari Arnau de Vilanova, Universitat de Lleida, Lleida (F.P.), and the Stroke Unit, Department of Neurology, Albacete University Hospital, Universidad de Castilla-La Mancha, Albacete (T.S.) - all in Spain; the Department of Neurology, Nowon Eulji Medical Center, Eulji University, Seoul, South Korea (J.M.P.); the Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford (P.M.R.), and the National Heart and Lung Institute Imperial College, Institute of Cardiovascular Medicine and Science Royal Brompton Hospital, London (P.G.S.) - both in the United Kingdom; the International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo (S.U.); the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing (Y.W.); and the Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (L.K.S.W.).

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http://dx.doi.org/10.1056/NEJMoa1802712DOI Listing
June 2018

Time course of blood pressure control prior to lacunar TIA and stroke: Population-based study.

Neurology 2018 05 18;90(20):e1732-e1741. Epub 2018 Apr 18.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neuroscience University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957302PMC
May 2018

Age-Specific Associations of Renal Impairment With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Transient Ischemic Attack and Stroke.

Stroke 2018 04 9;49(4):899-904. Epub 2018 Mar 9.

From the Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences University of Oxford, United Kingdom (B.L., K.K.L., L.L., C.L., W.K., P.M.R.); and Department of Neurology, Cerebrovascular Centre, West China Hospital, Sichuan University (B.L., M.L.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895118PMC
April 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-018-0058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

External Validation of Risk Scores for Major Bleeding in a Population-Based Cohort of Transient Ischemic Attack and Ischemic Stroke Patients.

Stroke 2018 03 19;49(3):601-606. Epub 2018 Feb 19.

From the Julius Center for Health Sciences and Primary Care (N.A.H., A.A., J.P.G.) and Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (A.A.), University Medical Center Utrecht, Utrecht University, the Netherlands; and Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839707PMC
March 2018

Early time course of major bleeding on antiplatelet therapy after TIA or ischemic stroke.

Neurology 2018 02 26;90(8):e683-e689. Epub 2018 Jan 26.

From the Julius Center for Health Sciences and Primary Care (N.A.H., A.A., J.P.G.) and Department of Neurology and Neurosurgery (A.A., L.J.K.), Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, the Netherlands; Stroke Trials Unit (P.M.B.), Division of Clinical Neuroscience, University of Nottingham, UK; Department of Neurology (L.C.), University of Debrecen Medical and Health Science Center, Hungary; and Stroke Prevention Research Unit (P.M.R.), Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818163PMC
February 2018

Time-of-Day Could Affect Cognitive Screening Performance in Older Patients with TIA and Stroke.

Cerebrovasc Dis 2017 21;43(5-6):290-293. Epub 2017 Mar 21.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1159/000456673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475237PMC
January 2018

Prognostic Significance of Blood Pressure Variability on Beat-to-Beat Monitoring After Transient Ischemic Attack and Stroke.

Stroke 2018 01 11;49(1):62-67. Epub 2017 Dec 11.

From the Department of Clinical Neurosciences, Centre for Prevention of Stroke and Dementia, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.117.019107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742536PMC
January 2018

Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack.

Stroke 2018 01 15;49(1):54-61. Epub 2017 Dec 15.

From the Stroke Research Group, Clinical Neurosciences, University of Cambridge, United Kingdom (R.L.B., H.S.M.); Division of Health and Social Care Research, Faculty of Life Sciences and Medicine, King's College London, United Kingdom (S.C., C.D.A.W.); National Epidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario (Q.Y.); School of Medicine and Pharmacology, The University of Western Australia, Perth (G.J.H.); Department of Neurology, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Western Australian Neuroscience Research Institute, Perth (G.J.H.); and Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (L.L., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753817PMC
January 2018

Antiplatelet cessation to manage bleeding events in elderly people - Authors' reply.

Lancet 2017 12 8;390(10112):2548. Epub 2017 Dec 8.

Centre for Prevention of Stroke and Dementia, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)33087-8DOI Listing
December 2017

Confounding by Pre-Morbid Functional Status in Studies of Apparent Sex Differences in Severity and Outcome of Stroke.

Stroke 2017 10 10;48(10):2731-2738. Epub 2017 Aug 10.

From the Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada (C.R., J.C.); Departments of Neurology and Neurosurgery (C.R.) and Epidemiology and Biostatistics (C.R.), McGill University, Montréal, Québec, Canada; and Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, United Kingdom (C.R., L.L., A.G., L.S., P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610564PMC
October 2017

Global stroke statistics: An update of mortality data from countries using a broad code of "cerebrovascular diseases".

Int J Stroke 2017 10 12;12(8):796-801. Epub 2017 Sep 12.

2 Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, USA.

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http://dx.doi.org/10.1177/1747493017730782DOI Listing
October 2017

Stenting for symptomatic vertebral artery stenosis: The Vertebral Artery Ischaemia Stenting Trial.

Neurology 2017 Sep 23;89(12):1229-1236. Epub 2017 Aug 23.

From the Stroke Research Group (H.S.M., S.C.L.), Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus; Nuffield Department of Clinical Neurosciences (W.K., U.G.S., P.M.R.), John Radcliffe Hospital, University of Oxford; Robertson Centre for Biostatistics (I.F.), University of Glasgow; and Department of Neuroradiology (A.C.), St. George's Hospital, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606920PMC
September 2017

Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation.

Stroke 2017 08 23;48(8):2292-2296. Epub 2017 May 23.

From the Acute Stroke Programme, Radcliffe Department of Medicine, John Radcliffe Hospital (Y.C., A.A.N., A.M.B.), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital (N.A.), Target Discovery Institute, Nuffield Department of Medicine (S.D., R.F.), and Centre for Prevention of Stroke and Dementia, John Radcliffe Hospital, Nuffield Department of Clinical Neurosciences (P.M.R., A.I.B.), University of Oxford, United Kingdom; and Turku Centre for Biotechnology, University of Turku, Biocity, Finland (A.M.D.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531255PMC
August 2017

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org.

Stroke 2017 07 5;48(7):1779-1787. Epub 2017 Jun 5.

From the APHP, Department of Neurology and Stroke Center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, France (T.H., L.S., P.C.L., P-J.T., P.A.); Clinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo, Japan (S.U.); Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital (L.K.S.W.); Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center, CA (G.W.A.); Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Israel (N.M.B.); Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA (L.R.C.); The Florey Institute of Neuroscience and Mental Health, the University of Melbourne, Parkville, VIC, Australia (G.A.D.); Department of Neurosciences, Hospital Santa Maria, University of Lisbon, Portugal (J.M.F.); Department of Neurology, Universitäts Medizin Mannheim, Heidelberg, Germany (M.G.H.); Université de Lille, CHU Lille, EA 2694-Santé publique: épidémiologie et qualité des soins, France (J.L.); Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Universitat Autonoma de Barcelona, Spain (C.M.); Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, United Kingdom (P.M.R.); APHP, Department of Cardiology, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, Hôpital Bichat, France, and NHLI Imperial College, ICMS Royal Brompton Hospital, London, United Kingdom (P.G.S.); APHP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal Hospital, France (É.V.).

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July 2017

Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study.

Lancet 2017 07 13;390(10093):490-499. Epub 2017 Jun 13.

Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30770-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537194PMC
July 2017

Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms.

Stroke 2017 06 3;48(6):1451-1456. Epub 2017 May 3.

From the Stroke Research Center (C.D.A., J.R.), Center for Human Genetic Research (C.D.A., J.R.), and Cardiovascular Research Center (S.A.L., L.-C.W., P.T.E.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, The Broad Insitute of Harvard and MIT, Cambridge, MA (S.A.L., L.-C.W., C.D.A., J.R., P.T.E.); Autism Research Centre (O.E.P.) and Department of Clinical Neurosciences (H.S.M., M.T.), University of Cambridge, United Kingdom; Boston University and National Heart, Lung and Blood Institute's Framingham Heart Study, MA (E.J.B.); Section of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, MA (E.J.B.); Department of Epidemiology, Boston University School of Public Health, MA (E.J.B.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians Universität, Germany (R.M., M.D.); Munich Cluster of Systems Neurology (SyNergy), Germany (M.D.); Division of Clinical Neurosciences, Neuroimaging Sciences and Institute of Genetics and Molecular Medicine, University of Edinburgh, United Kingdom (C.L.S.); and Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, United Kingdom (P.M.R.).

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http://dx.doi.org/10.1161/STROKEAHA.116.016198DOI Listing
June 2017

White Matter Imaging Correlates of Early Cognitive Impairment Detected by the Montreal Cognitive Assessment After Transient Ischemic Attack and Minor Stroke.

Stroke 2017 06 9;48(6):1539-1547. Epub 2017 May 9.

From the Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital (G.Z., L.G., S.M., L.L., W.K., S.T.P., P.M.R.) and Oxford Centre for Functional MRI of the Brain (FMRIB) (M.J.), Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.116.016044DOI Listing
June 2017

Clinical Correlates, Ethnic Differences, and Prognostic Implications of Perivascular Spaces in Transient Ischemic Attack and Ischemic Stroke.

Stroke 2017 06 11;48(6):1470-1477. Epub 2017 May 11.

From the Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (K.-K.L., L.L., C.E.L., G.Z., W.K., P.M.R.); Epsom and St Helier University Hospitals, NHS Trust, Carshalton, United Kingdom (C.E.L.); and Division of Neurology, Department of Medicine (K.-K.L., T.-T.C., M.-F.C., K.-T.L.) and Department of Diagnostic Radiology (H.K.-F.M.), Li Ka Shing Faculty of Medicine, University of Hong Kong.

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http://dx.doi.org/10.1161/STROKEAHA.117.016694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436733PMC
June 2017

Total small vessel disease score and risk of recurrent stroke: Validation in 2 large cohorts.

Neurology 2017 Jun 17;88(24):2260-2267. Epub 2017 May 17.

From the Centre for Prevention of Stroke and Dementia (K.K.L., L.L., U.S., M.S., W.K., P.M.R.), Nuffield Department of Clinical Neurosciences, University of Oxford, UK; and Division of Neurology, Department of Medicine (K.K.L., K.H.C., S.L.H., R.T.F.C.), and Department of Diagnostic Radiology (H.K.F.M.), Li Ka Shing Faculty of Medicine, University of Hong Kong.

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http://dx.doi.org/10.1212/WNL.0000000000004042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567324PMC
June 2017

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting.

Stroke 2017 04 13;48(4):1005-1010. Epub 2017 Mar 13.

From APHP, Department of Neurology and Stroke Center, Bichat Hospital, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, France (C.H., P.C.L., L.S., J.L., P.-J.T., P.A.); Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center (G.W.A.); Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Israel (N.M.B.); Department of Neurosciences (Neurology), Hospital Santa Maria, University of Lisbon, Portugal (J.M.F.); Cerebrovascular Disease Service, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA (L.R.C.); The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia (G.A.D.); Department of Neurology, UMM University Heidelberg, Germany (M.G.H.); Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Universitat Autonoma de Barcelona, Spain (C.M.); Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, University of Oxford, UK (P.M.R.); APHP, Department of Cardiology, INSERM LVTS-U1148, DHU FIRE, Université Paris-Diderot, Sorbonne-Paris Cité, Hôpital Bichat, Paris, France; and NHLI Imperial College, ICMS Royal Brompton Hospital London, UK (P.G.S.); Clinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo, Japan (S.U.); APHP, Department of Biostatistics, Université Paris-Diderot, Sorbonne-Paris Cité, Fernand Widal hospital, Paris, France (É.V.); and Department of Medicine & Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR (K.S.L.W.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015171DOI Listing
April 2017

Global stroke statistics.

Int J Stroke 2017 01 28;12(1):13-32. Epub 2016 Oct 28.

1 Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Australia.

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http://journals.sagepub.com/doi/10.1177/1747493016676285
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http://dx.doi.org/10.1177/1747493016676285DOI Listing
January 2017

Stroke research in 2016: when more medicine is better, and when it isn't.

Authors:
Peter M Rothwell

Lancet Neurol 2017 01;16(1):2-3

Centre for Prevention of Stroke and Dementia, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)30332-5DOI Listing
January 2017

Molecular magnetic resonance imaging discloses endothelial activation after transient ischaemic attack.

Brain 2017 01 8;140(1):146-157. Epub 2016 Nov 8.

1 Normandie Univ, UNICAEN, INSERM U919, Serine Proteases and Pathophysiology of the Neurovascular Unit, Cyceron, 14000 Caen, France

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http://dx.doi.org/10.1093/brain/aww260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226059PMC
January 2017

Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack: a pooled analysis of individual-patient data from cohort studies.

Lancet Neurol 2016 Nov 11;15(12):1238-1247. Epub 2016 Oct 11.

Neurovascular Clinical Science Unit, Stroke Service and Department of Neurology, Mater University Hospital/University College Dublin, Dublin Academic Medical Centre, Dublin, Ireland; Chelsea and Westminster NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(16)30236-8DOI Listing
November 2016

Brain Atrophy, N-Terminal Brain Natriuretic Peptide, and Carotid Disease: Interconnecting Relationships Between Cerebral Perfusion, Cardiovascular Disease, Inflammation, and Cognitive Decline.

Arterioscler Thromb Vasc Biol 2016 11;36(11):2141-2142

From the Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences (S.T.P., P.M.R.) and NIHR Oxford Biomedical Research Centre (S.T.P., P.M.R.), John Radcliffe Hospital, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1161/ATVBAHA.116.308362DOI Listing
November 2016

Recurrent stroke risk and cerebral microbleed burden in ischemic stroke and TIA: A meta-analysis.

Neurology 2016 Oct 2;87(14):1501-1510. Epub 2016 Sep 2.

From the Stroke Research Centre (D.W., A.C., S.G., P.R., D.J.W.), Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery; Department of Statistical Science (G.A.) and Biomedical Research Centre (Z.V.F.), UCL, London, UK; Department of Neurosurgery (T.I.), Kushiro City General Hospital, Hokkaido, Japan; Department of Neurology (F.F.), University Hospital Würzburg, Germany; Department of Neurology (H.N.), Suiseikai Kajikawa Hospital, Hiroshima, Japan; Department of Neurology (S.H.), University of Heidelberg, Germany; Department of Stroke Medicine (R.V.), Division of Brain Sciences, Imperial College London; Nuffield Department of Clinical Neurosciences (P.M.R.), John Radcliffe Hospital, University of Oxford, UK; Department of Neurology (V.I.H.K.), Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; Department of Neurology (V.T.), Austin Health and Melbourne Brain Center, University of Melbourne, Australia; Department of Neurology (Y.-S.L.), Seoul National University Boramae Medical Center; Department of Neurology (Y.D.K.), Yonsei University College of Medicine, Seoul, Korea; Department of Neurology (Y.H.), Peking University First Hospital, Beijing, China; Division of Neurology (K.S.W.), Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and Lysholm Department of Neuroradiology (H.R.J.), National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000003183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075978PMC
October 2016