Prof. Peter I Lelkes, PhD - Temple University, Dept. Bioengineering - Laura H. Carnell Professor and Chair

Prof. Peter I Lelkes

PhD

Temple University, Dept. Bioengineering

Laura H. Carnell Professor and Chair

Philadlephia, PA | United States

Main Specialties: Biotechnology

Additional Specialties: Tissue and Regenerative Engineering

ORCID logohttps://orcid.org/0000-0003-4954-3498


Top Author

Prof. Peter I Lelkes, PhD - Temple University, Dept. Bioengineering - Laura H. Carnell Professor and Chair

Prof. Peter I Lelkes

PhD

Introduction

Peter I. Lelkes, PhD is, since January 1, 2012, the Laura H. Carnell Professor and Founding Chair of the Department of Bioengineering in the College of Engineering at Temple University and the Inaugural Director of the Institute for Regenerative Medicine and Engineering (TIME) at Temple University’s School of Medicine. At Temple University, Dr. Lelkes is also a Professor of Mechanical Engineering (Dept. Mechanical Engineering), Regenerative Endodontics (School of Dentistry), and Cancer Biology (Fox Chase Cancer Center). From 2000-2011 he was the Calhoun Chair Professor in the School of Biomedical Engineering, Science and Health Systems at Drexel University in Philadelphia.

Dr. Lelkes obtained his PhD in Biophysics in 1977 from the Technical University (RWTH) Aachen, Germany. From 1977-1983 he was a postdoctoral fellow and then staff scientist in the Department of Membrane Research at the Weizmann Institute of Science, Rehovot, Israel, working on membrane fusion, exocytosis, and mechanisms of neurosecretion. From 1983-1988 he was a Visiting Scientist in the Laboratory of Cell Biology and Genetics, NIDDK (NIH), where became interested in translational biotechnology and tissue, studying the heterotypic interactions between endocrine cells and endothelial cells as. From 1988-2000, as Director of the Laboratory of Cell Biology in the Department of Medicine, University of Wisconsin, Dr. Lelkes developed a new program in vascular biology and biotechnology, focusing on the endothelialization of bioartificial cardiovascular devices. From 2000-2011 he was the Calhoun Chair Professor for Cellular Tissue Engineering in the School of Biomedical Engineering, Science and Health Systems at Drexel University in Philadelphia, coordinating the development of numerous translational biotechnological projects in collaboration with Drexel’s medical school and other academic institutions citywide and regionally. Specifically, Dr. Lelkes served as Director of the Surgical Engineering Enterprise, one of the major of initiative of the strategic plan of Drexel University’s College of Medicine. In addition, Dr. Lelkes was the team leader for applied tissue engineering at the Nanotechnology Institute of Southeastern Pennsylvania (NTI) and served as the Co-Director of PATRIC, the Pennsylvania Advanced Textile Research and Innovation Center, focusing on BioNanoTextiles.

Dr. Lelkes’ basic and translational research has been support by federal (NIH, NSF, NASA, DOE) and state funding agencies (NTI and PA Dept of Commerce, Tobacco Settlement Funds) and private Foundations, including the Coulter Foundation. He holds numerous patents in diverse areas of biomaterials and biomedical devices. He has served on numerous review panels regionally, nationally and internationally, where he not only was involved in evaluating the scientific merit of individual applications, but also participated in the prioritization of research projects and the allocation of funds.

Currently, Prof. Lelkes directs an interdisciplinary program in tissue engineering and regenerative medicine, focusing on nanotechnology-based biomaterials and soft tissue engineering (lung and skin), and employing developmental biological principles to enhance the tissue-specific differentiation of embryonic and adult stem cells. Dr. Lelkes has organized several Keystone conferences and published more than 200 peer-reviewed papers, edited several books, authored more than 65 book chapters and made more than 500 presentations nationally and internationally.

Dr. Lelkes has been received numerous honors and awards, nationally and internationally. Amongst them a Forchheimer Visiting Fellowship at the Hebrew University, Jerusalem, Honorary Professorships at The University of Applied Sciences Aachen, Germany and the Changchun Institute of Polymer Chemistry and Physics, Chinese Academy of Sciences, and a Distinguished Visiting Fellowship of the Royal Academy of Engineering at Imperial College, London, UK. In 2011 he was inducted as a Fellow of the AIMBE (American Institute for Medical and Biological Engineering) and received the 2012 Ben Franklin Key Award from IEEE, the Institute of Electrical and Electronics Engineers.

In his “free-time” Dr. Lelkes is an active chamber musician and likes to hike in the mountains.

Primary Affiliation: Temple University, Dept. Bioengineering - Philadlephia, PA , United States

Specialties:

Additional Specialties:

Research Interests:


View Prof. Peter I Lelkes’s Resume / CV

Metrics

Number of Publications

77

Publications

Number of Profile Views

496

Profile Views

Number of Article Reads

822

Reads

Number of Citations

864

Citations

Education

Jan 2012
Temple University, Philadelphia, PA
Laura H Carnell Professor and Chair, Dept. Bioengieering
Sep 2000
Drexel University, Philadelphia, PA
Calhoun Chair Professor
Jul 1988
U Wisconsin Med School, Madison
Associate/Full Professor
Aug 1983
NIH, NIADDK, Bethesda, MD
Visiting scientist
Jan 1977
Weizmann Institute, Israel
Postdoc/staff scientist
Oct 1967
RWTH Aachen, Germany
PhD

Experience

Apr 2011
Elected Fellow, American Institute of Biological and Medical Engineering
May 2010
Distinguished Visiting Fellow of the Royal Academy of Engineering at Imperial College, London

Top co-authors

Philip Lazarovici
Philip Lazarovici

School of Pharmacy Institute for Drug Research

26
Shimon Lecht
Shimon Lecht

College of Engineering

18
Mark J Mondrinos
Mark J Mondrinos

School of Biomedical Engineering

13
Cezary Marcinkiewicz
Cezary Marcinkiewicz

College of Engineering

13
Mengyan Li
Mengyan Li

School of Biomedical Engineering

9
Collin T Stabler
Collin T Stabler

College of Engineering

7
Anat Perets
Anat Perets

Drexel University

6
Yen Wei
Yen Wei

Tsinghua University

6
Xuesi Chen
Xuesi Chen

Key Laboratory of Polymer Ecomaterials

5

Publications

77Publications

822Reads

864PubMed Central Citations

A Bilayered Poly (Lactic-Co-Glycolic Acid) Scaffold Provides Differential Cues for the Differentiation of Dental Pulp Stem Cells.

Tissue Eng Part A 2018 Sep 13. Epub 2018 Sep 13.

1 Department of Bioengineering, College of Engineering, Temple University , Philadelphia, Pennsylvania.

View Article
September 2018
28 Reads

In Vivo Testing of Extracorporeal Membrane Ventilators: iLA-Activve Versus Prototype I-Lung.

ASAIO J 2017 Mar/Apr;63(2):185-192

From the *Institute for Experimental Surgery, Rostock University Medical Center, Rostock, Germany; †Department of General, Thoracic, Vascular and Transplantation Surgery, Rostock University Medical Center, Rostock, Germany; ‡Clinic for Anesthesiology and Intensive Care Medicine, Rostock University Medical Center, Rostock, Germany; §Novalung GmbH, Heilbronn, Germany; ¶Institute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Center, Rostock, Germany; ‖Clinic for Anesthesiology and Intensive Care Medicine, Südstadtklinikum Rostock, Germany; and #Department of Bioengineering, Temple University, Philadelphia, Pennsylvania.

View Article
October 2017
5 Reads
1.380 Impact Factor

Near infrared spectroscopic imaging assessment of cartilage composition: Validation with mid infrared imaging spectroscopy.

Anal Chim Acta 2016 Jul 25;926:79-87. Epub 2016 Apr 25.

Department of Bioengineering, Temple University, 1947 N. 12th St, Philadelphia, PA, USA. Electronic address:

View Article
July 2016
6 Reads
3 Citations
4.510 Impact Factor

Enhanced Re-Endothelialization of Decellularized Rat Lungs.

Tissue Eng Part C Methods 2016 05 1;22(5):439-50. Epub 2016 Apr 1.

1 Department of Bioengineering, College of Engineering, Temple University , Philadelphia, Pennsylvania.

View Article
May 2016
5 Reads
4 Citations

Revascularization of decellularized lung scaffolds: principles and progress.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 25;309(11):L1273-85. Epub 2015 Sep 25.

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, Pennsylvania;

View Article
December 2015
26 Reads
11 Citations
4.080 Impact Factor

Mesenchymal stem cells for therapeutic applications in pulmonary medicine.

Br Med Bull 2015 Sep 10;115(1):45-56. Epub 2015 Jun 10.

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA 19122, USA Temple Institute for Regenerative Medicine and Engineering (TIME), Temple University, Philadelphia, PA 19122, USA

View Article
September 2015
6 Reads
6 Citations
3.660 Impact Factor

Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.

Cell Signal 2015 Jun 5;27(6):1225-36. Epub 2015 Mar 5.

CoE Department of Bioengineering, Temple University, Philadelphia, PA, USA. Electronic address:

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June 2015
10 Reads
3 Citations
4.320 Impact Factor

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki.

Biochim Biophys Acta 2015 Jun 7;1850(6):1169-79. Epub 2015 Feb 7.

Temple University, College of Engineering, Department of Bioengineering, Philadelphia, PA, USA. Electronic address:

View Article
June 2015
6 Reads
3 Citations

Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer.

Trends Biotechnol 2015 Apr 20;33(4):230-6. Epub 2015 Feb 20.

Fox Chase Cancer Center, Cancer Biology, Temple Health, 333 Cottman Ave, Philadelphia, PA 19111, USA. Electronic address:

View Article
April 2015
7 Reads
35 Citations
11.960 Impact Factor

Hypoxia enhances differentiation of mouse embryonic stem cells into definitive endoderm and distal lung cells.

Stem Cells Dev 2015 Mar 27;24(5):663-76. Epub 2014 Oct 27.

1 Department of Biology, School of Science, Walailak University , Nakhon Si Thammarat, Thailand .

View Article
March 2015
18 Reads
7 Citations
3.730 Impact Factor

Osseointegrative properties of electrospun hydroxyapatite-containing nanofibrous chitosan scaffolds.

Tissue Eng Part A 2015 Mar 16;21(5-6):970-81. Epub 2014 Dec 16.

1 School of Biomedical Engineering, Science and Health Systems, Drexel University , Philadelphia, Pennsylvania.

View Article
March 2015
11 Reads
5 Citations

Mechanical study of polycaprolactone-hydroxyapatite porous scaffolds created by porogen-based solid freeform fabrication method.

J Appl Biomater Funct Mater 2014 Dec 30;12(3):145-54. Epub 2014 Dec 30.

Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, Pennsylvania - USA.

View Article
December 2014
6 Reads
0.900 Impact Factor

Cytocompatibility of novel extracellular matrix protein analogs of biodegradable polyester polymers derived from α-hydroxy amino acids.

J Biomater Sci Polym Ed 2014 25;25(6):608-24. Epub 2014 Feb 25.

a Department of Bioengineering and Temple Institute for Regenerative Medicine and Engineering , Temple University , Philadelphia , PA 19122 , USA.

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November 2014
9 Reads
1.650 Impact Factor

Engineering de novo assembly of fetal pulmonary organoids.

Tissue Eng Part A 2014 Nov 25;20(21-22):2892-907. Epub 2014 Jun 25.

1 Department of Bioengineering, Temple University , Philadelphia, Pennsylvania.

View Article
November 2014
10 Reads
8 Citations

Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells.

J Mol Neurosci 2014 Nov 31;54(3):574-85. Epub 2014 Jul 31.

Faculty of Medicine, School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

View Article
November 2014
7 Reads
2.340 Impact Factor

Textile-templated electrospun anisotropic scaffolds for regenerative cardiac tissue engineering.

Biomaterials 2014 Oct 10;35(30):8540-52. Epub 2014 Jul 10.

Temple University, Dept. Bioengineering, College of Engineering, Philadelphia, PA 19127, USA. Electronic address:

View Article
October 2014
13 Reads
8 Citations
8.560 Impact Factor

Heterogeneous mixed-lineage differentiation of mouse embryonic stem cells induced by conditioned media from a549 cells.

Stem Cells Dev 2014 Aug 3;23(16):1923-36. Epub 2014 Jun 3.

1 Department of Bioengineering, College of Engineering, Temple University , Philadelphia, Pennsylvania.

View Article
August 2014
11 Reads
3 Citations
3.730 Impact Factor

Neurotherapeutic effect of cord blood derived CD45+ hematopoietic cells in mice after traumatic brain injury.

J Neurotrauma 2014 Aug 14;31(16):1405-16. Epub 2014 Jul 14.

1 School of Pharmacy Institute for Drug Research, The Hebrew University of Jerusalem , Jerusalem, Israel .

View Article
August 2014
9 Reads
4 Citations
3.710 Impact Factor

Enhanced reseeding of decellularized rodent lungs with mouse embryonic stem cells.

Biomaterials 2014 Mar 15;35(10):3252-62. Epub 2014 Jan 15.

Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA 19122, USA. Electronic address:

View Article
March 2014
6 Reads
8 Citations
8.560 Impact Factor

Alimentary 'green' proteins as electrospun scaffolds for skin regenerative engineering.

J Tissue Eng Regen Med 2013 Dec 12;7(12):994-1008. Epub 2012 Apr 12.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

View Article
December 2013
7 Reads
3 Citations
5.200 Impact Factor

Neural stem cells: therapeutic potential for neurodegenerative diseases.

Br Med Bull 2012 17;104:7-19. Epub 2012 Sep 17.

The School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

View Article
November 2013
7 Reads
14 Citations
3.660 Impact Factor

Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

J Mol Neurosci 2013 Oct 12;51(2):249-61. Epub 2012 Dec 12.

School of Pharmacy, Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

View Article
October 2013
9 Reads
1 Citation
2.340 Impact Factor

Electrospun rapamycin-eluting polyurethane fibers for vascular grafts.

Pharm Res 2013 Jul 9;30(7):1735-48. Epub 2013 Apr 9.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, USA.

View Article
July 2013
14 Reads
1 Citation
3.420 Impact Factor

Tissue factor activity and ECM-related gene expression in human aortic endothelial cells grown on electrospun biohybrid scaffolds.

Biomacromolecules 2013 May 18;14(5):1338-48. Epub 2013 Apr 18.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, United States.

View Article
May 2013
9 Reads
3 Citations
5.750 Impact Factor

ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.

Neoplasia 2013 Apr;15(4):359-72

Department of Biochemistry and Molecular Biology, Molecular and Cellular Biology and Genetics Program, Drexel University College of Medicine, Philadelphia, PA, USA.

View Article
April 2013
10 Reads
7 Citations

Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair.

J Mol Neurosci 2013 Feb 10;49(2):334-46. Epub 2012 Aug 10.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

View Article
February 2013
9 Reads
3 Citations
2.340 Impact Factor

Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering.

Biomaterials 2012 Dec 27;33(36):9167-78. Epub 2012 Sep 27.

Drexel University, School of Biomedical Engineering, Science and Health System, Philadelphia, PA, USA.

View Article
December 2012
44 Reads
35 Citations
8.560 Impact Factor

Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.

Int J Dev Neurosci 2012 Oct 5;30(6):465-9. Epub 2012 Jun 5.

Integrated Cellular Tissue Engineering & Regenerative Medicine Laboratory, School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19102, USA.

View Article
October 2012
9 Reads
6 Citations
2.580 Impact Factor

Biocompatibility and biodegradation studies of PCL/β-TCP bone tissue scaffold fabricated by structural porogen method.

J Mater Sci Mater Med 2012 Sep 6;23(9):2217-26. Epub 2012 Jun 6.

Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA 19104, USA.

View Article
September 2012
14 Reads
4 Citations
2.590 Impact Factor

Mechanical properties and biomineralization of multifunctional nanodiamond-PLLA composites for bone tissue engineering.

Biomaterials 2012 Jul 9;33(20):5067-75. Epub 2012 Apr 9.

Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA 19104, USA.

View Article
July 2012
23 Reads
17 Citations
8.560 Impact Factor

Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1.

Mol Cancer Res 2012 Feb 8;10(2):183-96. Epub 2011 Dec 8.

Department of Biochemistry and Molecular BiologyDrexel University College of Medicine, Philadelphia, Pennsylvania, USA.

View Article
February 2012
12 Reads
20 Citations
4.380 Impact Factor

Cytotoxicity tests of water soluble ZnS and CdS quantum dots.

J Nanosci Nanotechnol 2011 Apr;11(4):3543-51

Department of Materials Science and Engineering, Drexel University, Philadelphia, PA 19104, USA.

View Article
April 2011
7 Reads
3 Citations
1.560 Impact Factor

Fibronectin-mediated upregulation of α5β1 integrin and cell adhesion during differentiation of mouse embryonic stem cells.

Cell Adh Migr 2011 Jan-Feb;5(1):73-82. Epub 2011 Jan 1.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

View Article
April 2011
12 Reads
11 Citations
4.500 Impact Factor

Co-electrospun blends of PLGA, gelatin, and elastin as potential nonthrombogenic scaffolds for vascular tissue engineering.

Biomacromolecules 2011 Feb 23;12(2):399-408. Epub 2010 Dec 23.

School of Biomedical Engineering, Science and Health Systems, Department of Chemistry, Drexel University, Philadelphia, Pennsylvania, 19104, USA.

View Article
February 2011
8 Reads
17 Citations
5.750 Impact Factor

Fluorescent PLLA-nanodiamond composites for bone tissue engineering.

Biomaterials 2011 Jan 24;32(1):87-94. Epub 2010 Sep 24.

Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, PA 19104, USA.

View Article
January 2011
23 Reads
32 Citations
8.560 Impact Factor

Transient signaling of Erk1/2, Akt and PLCgamma induced by nerve growth factor in brain capillary endothelial cells.

Vascul Pharmacol 2010 Sep-Oct;53(3-4):107-14. Epub 2010 Apr 29.

Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

View Article
December 2010
7 Reads
2 Citations
4.620 Impact Factor

Micropatterning of three-dimensional electrospun polyurethane vascular grafts.

Acta Biomater 2010 Nov 17;6(11):4229-37. Epub 2010 Jun 17.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

View Article
November 2010
5 Reads
11 Citations
6.030 Impact Factor

Peaceful use of disastrous neurotoxicants.

Neurotoxicology 2010 Sep 8;31(5):608-20. Epub 2010 Jul 8.

Service and Unit of Neurology and Toxicology, Shaare Zedek Medical Center, Jerusalem, Israel.

View Article
September 2010
7 Reads
2 Citations
3.380 Impact Factor

Fabrication of interconnected microporous biomaterials with high hydroxyapatite nanoparticle loading.

Biofabrication 2010 Sep 8;2(3):035006. Epub 2010 Sep 8.

School of Polymer Textile and Fiber Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

View Article
September 2010
17 Reads
4.290 Impact Factor

Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells.

Mol Cell Biochem 2010 Jun 11;339(1-2):201-13. Epub 2010 Feb 11.

School of Pharmacy-Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, POB 12065, Jerusalem 91120, Israel.

View Article
June 2010
6 Reads
7 Citations
2.390 Impact Factor

Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of Erk phosphorylation.

J Mol Neurosci 2010 May 10;41(1):183-92. Epub 2009 Dec 10.

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, POB 12065, Jerusalem, 91120, Israel.

View Article
May 2010
6 Reads
7 Citations
2.340 Impact Factor

Cardiac microvascular endothelial cells express and release nerve growth factor but not fibroblast growth factor-2.

In Vitro Cell Dev Biol Anim 2010 May 29;46(5):469-76. Epub 2010 Jan 29.

The School of Pharmacy Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

View Article
May 2010
8 Reads
2 Citations
1.150 Impact Factor

Efficient derivation of alveolar type II cells from embryonic stem cells for in vivo application.

Tissue Eng Part A 2009 Nov;15(11):3351-65

School of Biomedical Engineering, Sciences, and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, USA.

View Article
November 2009
7 Reads
37 Citations

Sub-mitogenic phorbol myristate acetate co-stimulation rescues the PHA-induced activation of both naïve and memory T cells cultured in the rotating-wall vessel bioreactor.

Cell Biol Int 2009 Aug 9;33(8):882-6. Epub 2009 May 9.

School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut St., Bossone Bldg. Rm. 707, Philadelphia, PA 19104, USA.

View Article
August 2009
8 Reads
1 Citation
1.930 Impact Factor

Quantitative assessment of neuronal differentiation in three-dimensional collagen gels using enhanced green fluorescence protein expressing PC12 pheochromocytoma cells.

J Mol Neurosci 2009 Mar 16;37(3):225-37. Epub 2008 Jul 16.

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.

View Article
March 2009
9 Reads
3 Citations
2.340 Impact Factor

A computational model of chemotaxis-based cell aggregation.

Biosystems 2008 Sep 28;93(3):226-39. Epub 2008 May 28.

Drexel University, Department of Computer Science, Philadelphia, PA 19104, United States.

View Article
September 2008
8 Reads
2 Citations
1.550 Impact Factor

Electrospun blends of natural and synthetic polymers as scaffolds for tissue engineering.

Conf Proc IEEE Eng Med Biol Soc 2005 ;6:5858-61

School of Biomedical Engineering, Science and Health Systems, Drexel University, USA.

View Article
September 2008
5 Reads
4 Citations

Templated synthesis of electroactive periodic mesoporous organosilica bridged with oligoaniline.

Chemistry 2008 ;14(9):2909-17

Department of Chemistry, Drexel University, Philadelphia, Pennsylvania 19104, USA.

View Article
June 2008
9 Reads
5.730 Impact Factor

Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425.

Cancer Biol Ther 2008 May 14;7(5):726-33. Epub 2008 May 14.

School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia, Pennsylvania 19107, USA.

View Article
May 2008
6 Reads
21 Citations
3.070 Impact Factor

Novel methods for delivery of cell-based therapies.

J Surg Res 2008 May 25;146(1):3-10. Epub 2007 Jul 25.

Department of Pediatric Surgery, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

View Article
May 2008
8 Reads
4 Citations
1.940 Impact Factor

In vivo pulmonary tissue engineering: contribution of donor-derived endothelial cells to construct vascularization.

Tissue Eng Part A 2008 Mar;14(3):361-8

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.

View Article
March 2008
10 Reads
20 Citations

Real-time assessment of three-dimensional cell aggregation in rotating wall vessel bioreactors in vitro.

Nat Protoc 2006 ;1(4):2116-27

Laboratory of Cellular and Tissue Engineering, Drexel University, New College Building, 245 N. 15th St., Philadelphia, Pennsylvania, USA.

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October 2007
6 Reads
4 Citations

Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer.

Biomaterials 2007 Apr 10;28(10):1741-51. Epub 2007 Jan 10.

State key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.

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April 2007
14 Reads
12 Citations
8.560 Impact Factor

Heterogeneous breast tumoroids: An in vitro assay for investigating cellular heterogeneity and drug delivery.

J Biomol Screen 2007 Feb 8;12(1):13-20. Epub 2006 Dec 8.

Center for Integrated Bioinformatics, School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

View Article
February 2007
6 Reads
14 Citations
2.420 Impact Factor

Fine-tuning of a three-dimensional microcarrier-based angiogenesis assay for the analysis of endothelial-mesenchymal cell co-cultures in fibrin and collagen gels.

Angiogenesis 2006 19;9(3):111-25. Epub 2006 Oct 19.

School of Biomedical Engineering, Science, and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

View Article
February 2007
7 Reads
20 Citations
4.880 Impact Factor

Co-electrospun poly(lactide-co-glycolide), gelatin, and elastin blends for tissue engineering scaffolds.

J Biomed Mater Res A 2006 Dec;79(4):963-73

School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.

View Article
December 2006
7 Reads
26 Citations
3.370 Impact Factor

[Research progresses on electroactive and electrically conductive polymers for tissue engineering scaffolds].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2006 Dec;28(6):845-8

School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia, PA 19104, USA.

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December 2006
14 Reads
1 Citation

Polyaniline, an electroactive polymer, supports adhesion and proliferation of cardiac myoblasts.

J Biomater Sci Polym Ed 2006 ;17(1-2):199-212

School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

View Article
October 2006
9 Reads
15 Citations
1.650 Impact Factor

A novel real-time system to monitor cell aggregation and trajectories in rotating wall vessel bioreactors.

J Biotechnol 2006 Sep 9;125(3):416-24. Epub 2006 May 9.

Laboratory of Cellular Tissue Engineering, School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.

View Article
September 2006
5 Reads
2 Citations
2.870 Impact Factor

Porogen-based solid freeform fabrication of polycaprolactone-calcium phosphate scaffolds for tissue engineering.

Biomaterials 2006 Sep 5;27(25):4399-408. Epub 2006 May 5.

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.

View Article
September 2006
7 Reads
20 Citations
8.560 Impact Factor

Nerve growth factor (NGF) promotes angiogenesis in the quail chorioallantoic membrane.

Endothelium 2006 Jan-Feb;13(1):51-9

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.

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September 2006
7 Reads
8 Citations

Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development.

Curr Pharm Des 2006 ;12(21):2609-22

Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.

View Article
August 2006
7 Reads
36 Citations
3.450 Impact Factor

Electrospinning polyaniline-contained gelatin nanofibers for tissue engineering applications.

Biomaterials 2006 May 13;27(13):2705-15. Epub 2005 Dec 13.

School of Biomedical Engineering, Science, and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

View Article
May 2006
26 Reads
38 Citations
8.560 Impact Factor

Engineering three-dimensional pulmonary tissue constructs.

Tissue Eng 2006 Apr;12(4):717-28

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.

View Article
April 2006
56 Reads
37 Citations
4.250 Impact Factor

Functional recovery of peripheral blood mononuclear cells in modeled microgravity.

FASEB J 2006 Feb 21;20(2):305-7. Epub 2005 Dec 21.

Department of Bioscience and Biotechnology, Drexel University, Philadelphia, Pennsylvania 19104, USA.

View Article
February 2006
9 Reads
2 Citations
5.040 Impact Factor

Topographic guidance of endothelial cells on silicone surfaces with micro- to nanogrooves: orientation of actin filaments and focal adhesions.

J Biomed Mater Res A 2005 Dec;75(3):668-80

Department of Materials Science and Engineering, University of Pennsylvania, 3451 Walnut Street, Philadelphia, PA 19104, USA.

View Article
December 2005
8 Reads
30 Citations
3.370 Impact Factor

Nerve growth factor-induced migration of endothelial cells.

J Pharmacol Exp Ther 2005 Dec 25;315(3):1220-7. Epub 2005 Aug 25.

Calhoun Chair Professor of Cellular Tissue Engineering, School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut St., Philadelphia, PA 19104, USA.

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December 2005
7 Reads
14 Citations
3.970 Impact Factor

Electrospun protein fibers as matrices for tissue engineering.

Biomaterials 2005 Oct;26(30):5999-6008

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19102, USA.

View Article
October 2005
7 Reads
61 Citations
8.560 Impact Factor

Gene expression profiling of vascular endothelial cells exposed to fluid mechanical forces: relevance for focal susceptibility to atherosclerosis.

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Gene Therapy Research Department, Berlex Biosciences, Richmond, California 94804-4099, USA.

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September 2004
7 Reads
20 Citations

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Endothelium 2004 Jan-Feb;11(1):11-6

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, USA.

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September 2004
7 Reads
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Adrenal medullary function and expression of catecholamine-synthesizing enzymes in mice with hypothalamic obesity.

Life Sci 2004 May;74(26):3211-22

Department of Cell Biology and Genetics, State University of Maringá, Maringá, PR, Brazil.

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May 2004
9 Reads
3 Citations
2.700 Impact Factor

Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow.

Physiol Genomics 2002 ;9(1):27-41

Gene Therapy Research Department, Berlex Biosciences, Richmond, California 94804, USA.

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April 2002
7 Reads
66 Citations
2.370 Impact Factor

Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion.

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Laboratory of Cell Biology, Department of Medicine, University of Wisconsin Medical School, Milwaukee, USA.

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April 2002
8 Reads
12 Citations
6.000 Impact Factor

Top co-authors

Philip Lazarovici
Philip Lazarovici

School of Pharmacy Institute for Drug Research

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Shimon Lecht
Shimon Lecht

College of Engineering

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Mark J Mondrinos
Mark J Mondrinos

School of Biomedical Engineering

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Cezary Marcinkiewicz
Cezary Marcinkiewicz

College of Engineering

13
Mengyan Li
Mengyan Li

School of Biomedical Engineering

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Collin T Stabler
Collin T Stabler

College of Engineering

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Anat Perets
Anat Perets

Drexel University

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Yen Wei
Yen Wei

Tsinghua University

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Xuesi Chen
Xuesi Chen

Key Laboratory of Polymer Ecomaterials

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