Peter Krajcsi

Peter Krajcsi

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Peter Krajcsi

Peter Krajcsi

Publications by authors named "Peter Krajcsi"

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59Publications

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Age-Related Functional and Expressional Changes in Efflux Pathways at the Blood-Brain Barrier.

Front Aging Neurosci 2019 30;11:196. Epub 2019 Jul 30.

Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary.

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http://dx.doi.org/10.3389/fnagi.2019.00196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682691PMC
July 2019

ABCG2/BCRP: variants, transporter interaction profile of substrates and inhibitors.

Expert Opin Drug Metab Toxicol 2019 Apr 16;15(4):313-328. Epub 2019 Mar 16.

a SOLVO Biotechnology , Szeged , Hungary.

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http://dx.doi.org/10.1080/17425255.2019.1591373DOI Listing
April 2019

Correlation Analysis of Potential Breast Cancer Resistance Protein Probes in Different Monolayer Systems.

J Pharm Sci 2018 11 25;107(11):2742-2747. Epub 2018 Jul 25.

Solvo Biotechnology, Gyár utca 2, Budaörs H-2040 Hungary; Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, 17 Vas u., Budapest H-1088, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2018.07.014DOI Listing
November 2018

Human OATP1B1 (SLCO1B1) transports sulfated bile acids and bile salts with particular efficiency.

Toxicol In Vitro 2018 Oct 19;52:189-194. Epub 2018 Jun 19.

Solvo Biotechnology, 2 Gyár str, Budaörs H-2040, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2018.06.018DOI Listing
October 2018

Baicalin is a substrate of OATP2B1 and OATP1B3.

Phytother Res 2018 Aug 19;32(8):1647-1650. Epub 2018 Apr 19.

SOLVO Biotechnology, 2 Gyár utca, Budaörs, H-2040, Hungary.

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http://dx.doi.org/10.1002/ptr.6095DOI Listing
August 2018

Kinetic characterization of bile salt transport by human NTCP (SLC10A1).

Toxicol In Vitro 2018 Feb 9;46:189-193. Epub 2017 Oct 9.

Institut de Recherches Internationales Servier (I.R.I.S.), 50, rue Carnot, 92284 Suresnes Cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2017.10.012DOI Listing
February 2018

Membrane Transporters in Physiological Barriers of Pharmacological Importance.

Curr Pharm Des 2016 ;22(35):5347-5372

Solvo Biotechnology, Budaörs, Gyár u. 2, 2040, Hungary.

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http://dx.doi.org/10.2174/1381612822666160726101748DOI Listing
December 2017

Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2).

Drug Metab Pharmacokinet 2017 Jun 26;32(3):165-171. Epub 2016 Aug 26.

SOLVO Biotechnology, 2 Gyár utca, Budaörs 2040, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.dmpk.2016.08.005DOI Listing
June 2017

Abcb1a (P-glycoprotein) limits brain exposure of the anticancer drug candidate seliciclib in vivo in adult mice.

Brain Res Bull 2017 06 16;132:232-236. Epub 2017 Jun 16.

SOLVO Biotechnology, Gyár u. 2, Budaörs, 2040 Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.brainresbull.2017.06.013DOI Listing
June 2017

Multiple ABC Transporters Efflux Baicalin.

Phytother Res 2015 Dec 24;29(12):1987-90. Epub 2015 Sep 24.

Department of Pharmaceutics, Semmelweis University, Hőgyes E. utca 7., H-1092, Budapest, Hungary.

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http://dx.doi.org/10.1002/ptr.5477DOI Listing
December 2015

Mechanisms and therapeutic potential of inhibiting drug efflux transporters.

Expert Opin Drug Metab Toxicol 2015 Jun 24;11(6):907-20. Epub 2015 Mar 24.

SOLVO Biotechnology , Gyár u. 2, 2040 Budaörs , Hungary.

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http://dx.doi.org/10.1517/17425255.2015.1028917DOI Listing
June 2015

Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.

Arch Toxicol 2014 Jun 29;88(6):1205-48. Epub 2014 Apr 29.

Solvo Biotechnology, Budaörs, Szeged, Hungary.

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http://dx.doi.org/10.1007/s00204-014-1224-8DOI Listing
June 2014

MDR-ABC transporters: biomarkers in rheumatoid arthritis.

Clin Exp Rheumatol 2013 Sep-Oct;31(5):779-87. Epub 2013 May 27.

Solvo Biotechnology, Budaörs, Hungary.

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December 2013

Synthesis and ABCG2 inhibitory activity of novel fumitremorgin C analogs--specificity and structure activity correlations.

Med Chem 2013 Jun;9(4):494-509

Department of Medical Chemistry, Faculty of General Medicine, University of Szeged, 6720 Szeged Dóm tér 8., Hungary.

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http://dx.doi.org/10.2174/1573406411309040003DOI Listing
June 2013

BSEP inhibition: in vitro screens to assess cholestatic potential of drugs.

Toxicol In Vitro 2012 Dec 18;26(8):1294-9. Epub 2011 Nov 18.

Solvo Biotechnology, Hungary.

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http://dx.doi.org/10.1016/j.tiv.2011.11.002DOI Listing
December 2012

Efflux transporters in the blood-brain interfaces--in vitro and in vivo methods and correlations.

Expert Opin Drug Metab Toxicol 2012 Apr 6;8(4):419-31. Epub 2012 Mar 6.

Solvo Biotechnology, Gyár u 2. 2040-Budaörs, Hungary.

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http://dx.doi.org/10.1517/17425255.2012.668184DOI Listing
April 2012

Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells.

Biopharm Drug Dispos 2011 Dec 21;32(9):530-5. Epub 2011 Nov 21.

Nestlé Research Center, Nestec Ltd, Vers-chez-les-Blanc, PO Box 44, 1000 Lausanne, 26, Switzerland.

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http://dx.doi.org/10.1002/bdd.780DOI Listing
December 2011

Hepatic metabolism and disposition of baicalein via the coupling of conjugation enzymes and transporters-in vitro and in vivo evidences.

AAPS J 2011 Sep 24;13(3):378-89. Epub 2011 May 24.

School of Pharmacy Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, People's Republic of China.

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http://dx.doi.org/10.1208/s12248-011-9277-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160155PMC
September 2011

Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters.

Mol Nutr Food Res 2011 Jul 29;55(7):979-88. Epub 2011 Apr 29.

School of Food Science and Nutrition, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1002/mnfr.201000652DOI Listing
July 2011

Ivermectin interacts with human ABCG2.

J Pharm Sci 2011 Jan 22;100(1):94-7. Epub 2010 Jun 22.

Solvo Biotechnology, Budaörs, Hungary.

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http://dx.doi.org/10.1002/jps.22262DOI Listing
January 2011

ABCC2/Abcc2: a multispecific transporter with dominant excretory functions.

Drug Metab Rev 2010 Aug;42(3):402-36

Chemical Research Center, Institute of Biomolecular Chemistry, HAS, Budapest, Hungary.

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http://dx.doi.org/10.3109/03602530903491741DOI Listing
August 2010

Effect of membrane cholesterol on BSEP/Bsep activity: species specificity studies for substrates and inhibitors.

Drug Metab Dispos 2009 Sep 11;37(9):1878-86. Epub 2009 Jun 11.

Solvo Biotechnology, Szeged, Hungary.

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http://dx.doi.org/10.1124/dmd.108.024778DOI Listing
September 2009

Kinetic characterization of sulfasalazine transport by human ATP-binding cassette G2.

Biol Pharm Bull 2009 Mar;32(3):497-9

Solvo Biotechnology, Budaors, Hungary.

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http://dx.doi.org/10.1248/bpb.32.497DOI Listing
March 2009

A novel screening strategy to identify ABCB1 substrates and inhibitors.

Naunyn Schmiedebergs Arch Pharmacol 2009 Jan 29;379(1):11-26. Epub 2008 Aug 29.

Division of Drug Metabolism and Pharmacokinetics, Altana Pharma AG, Konstanz, Germany.

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http://link.springer.com/content/pdf/10.1007/s00210-008-0345
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http://link.springer.com/10.1007/s00210-008-0345-0
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http://dx.doi.org/10.1007/s00210-008-0345-0DOI Listing
January 2009

Specific interactions of chloroacetanilide herbicides with human ABC transporter proteins.

Toxicology 2008 Jun 14;248(1):45-51. Epub 2008 Mar 14.

SOLVO Biotechnology, Gyár utca 2, 2040 Budaörs, Hungary.

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http://dx.doi.org/10.1016/j.tox.2008.03.003DOI Listing
June 2008

Utilization of membrane vesicle preparations to study drug-ABC transporter interactions.

Expert Opin Drug Metab Toxicol 2008 Jun;4(6):721-32

Solvo Biotechnology, Gyár u 2, Budaörs, 2040, Hungary.

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http://dx.doi.org/10.1517/17425255.4.6.721DOI Listing
June 2008

Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes.

Hepatol Res 2008 Mar 29;38(3):300-9. Epub 2007 Aug 29.

Department of Biochemical Pharmacology, Institute of Biomolecular Chemistry, Chemical Research Center, Hungarian Academy of Science, Budapest, Hungary.

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http://dx.doi.org/10.1111/j.1872-034X.2007.00255.xDOI Listing
March 2008

A real-time PCR method to rapidly titer adenovirus stocks.

Methods Mol Med 2007 ;130:185-92

Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.

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http://link.springer.com/content/pdf/10.1385/1-59745-166-5:1
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http://dx.doi.org/10.1385/1-59745-166-5:185DOI Listing
August 2007

Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2).

Drug Metab Dispos 2007 Aug 3;35(8):1262-8. Epub 2007 May 3.

Nestlé Research Center, Vers Chez Les Blanc, 1000 Lausanne 26, Switzerland.

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http://dx.doi.org/10.1124/dmd.106.014241DOI Listing
August 2007

Mechanistic study on the intestinal absorption and disposition of baicalein.

Eur J Pharm Sci 2007 Jul 9;31(3-4):221-31. Epub 2007 Apr 9.

School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, PR China.

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http://dx.doi.org/10.1016/j.ejps.2007.04.001DOI Listing
July 2007

Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3).

Chem Biol Interact 2006 Feb 27;159(3):169-79. Epub 2005 Dec 27.

Laboratoire de Pharmacologie-Toxicologie INRA, Toulouse, France.

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http://dx.doi.org/10.1016/j.cbi.2005.11.002DOI Listing
February 2006

The role of ABC transporters in drug resistance, metabolism and toxicity.

Curr Drug Deliv 2004 Jan;1(1):27-42

SOLVO Biotechnology, Szeged, Hungary.

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http://dx.doi.org/10.2174/1567201043480036DOI Listing
January 2004

Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus.

Virology 2003 Jan;305(2):378-87

Department of Molecular Microbiology and Immunology, St. Louis University School of Medicine, Missouri 63104, USA.

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http://dx.doi.org/10.1006/viro.2002.1772DOI Listing
January 2003

In Silico and Ex silico ADME approaches for drug discovery.

Curr Top Med Chem 2002 Dec;2(12):1287-304

ComGenex Inc, Bem rkp 33-34, Budapest, H-1024, Hungary.

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http://dx.doi.org/10.2174/1568026023392841DOI Listing
December 2002

Adenovirus RIDbeta subunit contains a tyrosine residue that is critical for RID-mediated receptor internalization and inhibition of Fas- and TRAIL-induced apoptosis.

J Virol 2002 Nov;76(22):11329-42

Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri 63104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136796PMC
http://dx.doi.org/10.1128/jvi.76.22.11329-11342.2002DOI Listing
November 2002

Enantioselective plasma protein binding of bimoclomol.

Chirality 2002 Aug;14(8):638-42

Department of Molecular Pharmacology, Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1002/chir.10117DOI Listing
August 2002