Peter Kang

Peter Kang

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Peter Kang

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Testing monotherapy and combination therapy in one trial with biomarker consideration.

Contemp Clin Trials 2019 Jul 12;82:53-59. Epub 2019 Jun 12.

MRL, Merck & Co., Inc., Kenilworth, NJ, USA.

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http://dx.doi.org/10.1016/j.cct.2019.06.002DOI Listing
July 2019

Neurodevelopmental outcomes at 9-14 months gestational age after treatment of neonatal seizures due to brain injury.

Childs Nerv Syst 2019 Jul 5. Epub 2019 Jul 5.

Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, 1600 SW Archer Rd, Gainesville, FL, 32610, USA.

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http://dx.doi.org/10.1007/s00381-019-04286-xDOI Listing
July 2019

AAV9- Gene Replacement Ameliorates Cardiac TMT Proteomic Profiles in a Mouse Model of Barth Syndrome.

Mol Ther Methods Clin Dev 2019 Jun 25;13:167-179. Epub 2019 Jan 25.

Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.1016/j.omtm.2019.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369239PMC
June 2019

Intravenous Immunoglobulin as a Therapeutic Option for Encephalitis.

J Child Neurol 2019 Jun 11:883073819854854. Epub 2019 Jun 11.

2 Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA.

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http://dx.doi.org/10.1177/0883073819854854DOI Listing
June 2019

The impact of Megf10/Drpr gain-of-function on muscle development in Drosophila.

FEBS Lett 2019 Apr 12;593(7):680-696. Epub 2019 Mar 12.

Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA.

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http://dx.doi.org/10.1002/1873-3468.13348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504253PMC
April 2019

Lumbosacral ventral spinal nerve root atrophy identified on MRI in a case of spinal muscular atrophy type II.

Clin Imaging 2019 Jan - Feb;53:134-137. Epub 2018 Oct 5.

Department of Radiology, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08997071183025
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http://dx.doi.org/10.1016/j.clinimag.2018.09.017DOI Listing
March 2019

Hyperbilirubinemia as a Predictor of Appendiceal Perforation: A Systematic Review and Diagnostic Test Meta-Analysis.

J Clin Med Res 2019 Mar 13;11(3):171-178. Epub 2019 Feb 13.

Department of General and Colorectal Surgery, Northampton General Hospital NHS Trust, Northampton, UK.

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http://dx.doi.org/10.14740/jocmr3724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396786PMC
March 2019

Targeting Oxidative Stress Using Nanoparticles as a Theranostic Strategy for Cardiovascular Diseases.

Antioxid Redox Signal 2019 Feb 30;30(5):733-746. Epub 2018 Jan 30.

1 Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1089/ars.2017.7428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350062PMC
February 2019

Dollars and antisense for Duchenne muscular dystrophy: Eteplirsen and dystrophin.

Neurology 2018 Jun 11;90(24):1091-1092. Epub 2018 May 11.

From the Department of Neurology (C.D.Z.), University of Pennsylvania, Philadelphia; Division of Pediatric Neurology (P.B.K.), Department of Pediatrics, and Departments of Neurology (P.B.K.), and Molecular Genetics and Microbiology (P.B.K.), University of Florida College of Medicine; and Genetics Institute and Myology Institute (P.B.K.), University of Florida, Gainesville.

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http://dx.doi.org/10.1212/WNL.0000000000005669DOI Listing
June 2018

Electrophysiologic Features of Radial Neuropathy in Childhood and Adolescence.

Pediatr Neurol 2018 04 31;81:14-18. Epub 2018 Jan 31.

Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts; Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida; Department of Neurology, University of Florida College of Medicine, Gainesville, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2018.01.003DOI Listing
April 2018

Early Actions of Anti-Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Drugs on Angiogenic Blood Vessels.

Am J Pathol 2017 Oct 21;187(10):2337-2347. Epub 2017 Jul 21.

The Center for Vascular Biology Research and the Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809587PMC
October 2017

A 42-Year-Old Man with AIDS and Multiple Incomplete Ring Enhancing Lesions.

Brain Pathol 2017 09;27(5):697-698

Department of Neurology, Washington University School of Medicine, St Louis, MO.

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http://dx.doi.org/10.1111/bpa.12542DOI Listing
September 2017

Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling.

Neuron 2017 Sep;96(1):190-206.e7

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637454PMC
September 2017

Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.

Hum Mol Genet 2017 08;26(15):2984-3000

Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610, USA.

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https://academic.oup.com/hmg/article/26/15/2984/3819203
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http://dx.doi.org/10.1093/hmg/ddx189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075367PMC
August 2017

Teaching Neuro: Cerebral amyloid angiopathy-related inflammation presenting with isolated leptomeningitis.

Neurology 2017 08;89(6):e66-e67

From the Department of Neurology (P.K., R.C.B., A.H.K., G.S.D.), Division of Neuropathology, Department of Pathology and Immunology (C.J.F., J.C.C.), and Department of Neurological Surgery (A.H.K.), Washington University School of Medicine; and Knight Alzheimer Disease Research Center (G.S.D.), St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000004218DOI Listing
August 2017

Reversible Rhombencephalitis in Neuro-Behçet's Disease.

Neurohospitalist 2017 Jul 27;7(3):148-149. Epub 2016 Sep 27.

Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1177/1941874416670070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467813PMC
July 2017

Neuropeptide Y incorporated into PVAX nanoparticle improves functional blood flow in a murine model of hind limb ischemia.

J Appl Physiol (1985) 2017 Jun 16;122(6):1388-1397. Epub 2017 Mar 16.

Department of Anesthesia, Critical Care & Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts; and

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http://dx.doi.org/10.1152/japplphysiol.00467.2016DOI Listing
June 2017

The role of thymectomy in the treatment of juvenile myasthenia gravis: a systematic review.

Pediatr Surg Int 2017 Jun 11;33(6):683-694. Epub 2017 Apr 11.

Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00383-017-4086-3DOI Listing
June 2017

Fibrin-Targeted and HO-Responsive Nanoparticles as a Theranostics for Thrombosed Vessels.

ACS Nano 2017 06 18;11(6):6194-6203. Epub 2017 May 18.

Department of Nuclear Medicine, Seoul National University College of Medicine , Seoul 151-742, Korea.

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http://dx.doi.org/10.1021/acsnano.7b02308DOI Listing
June 2017

Electrophysiologic features of fibular neuropathy in childhood and adolescence.

Muscle Nerve 2017 05 24;55(5):693-697. Epub 2017 Jan 24.

Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.25403DOI Listing
May 2017

Electrophysiologic features of ulnar neuropathy in childhood and adolescence.

Clin Neurophysiol 2017 05 20;128(5):751-755. Epub 2017 Feb 20.

Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA; Department of Neurology, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clinph.2017.01.024DOI Listing
May 2017

Child Neurology Recruitment and Training: Views of Residents and Child Neurologists From the 2015 AAP/CNS Workforce Survey.

Pediatr Neurol 2017 01 3;66:89-95. Epub 2016 Oct 3.

Division of Pediatric Neurology, University of Utah School of Medicine, Salt Lake City, Utah.

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http://dx.doi.org/10.1016/j.pediatrneurol.2016.08.018DOI Listing
January 2017

Ethical issues in the evaluation of adults with suspected genetic neuromuscular disorders.

Muscle Nerve 2016 12 1;54(6):997-1006. Epub 2016 Oct 1.

Departments of Neurology and Humanities, Penn State Hershey Medical Center, 30 Hope Drive, Hershey, Pennsylvania, 17033, USA.

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http://dx.doi.org/10.1002/mus.25400DOI Listing
December 2016

Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease.

Am J Physiol Heart Circ Physiol 2016 12 30;311(6):H1392-H1408. Epub 2016 Sep 30.

Department of Pathology and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.1152/ajpheart.00463.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206344PMC
December 2016

Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma.

J Clin Oncol 2016 12 31;34(34):4102-4109. Epub 2016 Oct 31.

Adil I. Daud, University of California, San Francisco, San Francisco; Antoni Ribas, University of California, Los Angeles; Omid Hamid, The Angeles Clinic and Research Institute, Los Angeles; Charlotte Roach and Grant Toland, Dako North America, Carpinteria, CA; Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center, New York, NY; Wen-Jen Hwu, The University of Texas MD Anderson Cancer Center, Houston; Amita Patnaik, South Texas Accelerated Research Therapeutics, San Antonio, TX; Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa; Richard Joseph, Mayo Clinic, Jacksonville, FL; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Tara C. Gangadhar, Abramson Cancer Center at the University of Pennsylvania, Philadelphia; Hassane Zarour, University of Pittsburgh, Pittsburgh, PA; Roxana Dronca, Mayo Clinic, Rochester, MN; Jared K. Lunceford, Xiaoyun Nicole Li, Kenneth Emancipator, Marisa Dolled-Filhart, S. Peter Kang, and Scot Ebbinghaus, Merck & Co, Kenilworth, NJ; Caroline Robert, Gustave Roussy and Paris-Sud University, Villejuif, France; Anthony M. Joshua, Princess Margaret Cancer Centre, Toronto, ON, Canada; Richard Kefford, Crown Princess Mary Cancer Centre, Westmead Hospital and Melanoma Institute Australia; Richard Kefford, Macquarie University; and Richard Kefford and Peter Hersey, University of Sydney, Sydney, NSW, Australia.

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http://ascopubs.org/doi/10.1200/JCO.2016.67.2477
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http://dx.doi.org/10.1200/JCO.2016.67.2477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562434PMC
December 2016

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.

Eur J Cancer 2016 11 2;67:46-54. Epub 2016 Sep 2.

Department of Medicine, Division of Hematology-Oncology, Jonsson Comprehensive Cancer Center (JCCC) at the University of California, Los Angeles (UCLA), 10833 Le Conte Ave, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049163234
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http://dx.doi.org/10.1016/j.ejca.2016.07.018DOI Listing
November 2016

Longitudinal Patterns of Thalidomide Neuropathy in Children and Adolescents.

J Pediatr 2016 Nov 24;178:227-232. Epub 2016 Aug 24.

Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA; Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2016.07.040DOI Listing
November 2016

Homozygous nonsense mutation in SGCA is a common cause of limb-girdle muscular dystrophy in Assiut, Egypt.

Muscle Nerve 2016 10 24;54(4):690-5. Epub 2016 Aug 24.

Division of Pediatric Neurology, University of Florida College of Medicine, PO Box 100296, Gainesville, Florida, USA, 32610.

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http://dx.doi.org/10.1002/mus.25094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453499PMC
October 2016

Diagnostic and Therapeutic Nanoparticles in Cardiovascular Diseases.

Curr Pharm Des 2015 ;21(42):6070-80

Cardiovascular Institute, Beth Israel Deaconess Medical Center, 3 Blackfan Circle, CLS 910, Boston, MA 02215.

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September 2016

H2O2-responsive antioxidant polymeric nanoparticles as therapeutic agents for peripheral arterial disease.

Int J Pharm 2016 Sep 10;511(2):1022-32. Epub 2016 Aug 10.

Department of BIN Convergence Technology, Chonbuk National University, Jeonju, Chonbuk, 561-756, South Korea; Department of Polymer·Nano Science and Technology, Chonbuk National University, Jeonju, Chonbuk, 561-756, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2016.08.014DOI Listing
September 2016

The child neurology clinical workforce in 2015: Report of the AAP/CNS Joint Taskforce.

Neurology 2016 Sep 26;87(13):1384-92. Epub 2016 Aug 26.

From the Division of Pediatric Neurology (P.B.K.), Department of Pediatrics, University of Florida College of Medicine, Gainesville; Division of Pediatric Neurology (J.F.B.), University of Utah School of Medicine, Salt Lake City; The Center for Neurological and Neurodevelopmental Health and the Clinical Research Center of New Jersey (M.M.), Voorhees; Division of Pediatric Neurology (S.M.J.), Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor; Division of Pediatric Neurology (D.L.G.), Cincinnati Children's Hospital Medical Center, OH; and American Academy of Pediatrics Division of Workforce and Medical Education Policy (C.R., H.R.-R.), Elk Grove Village, IL.

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http://dx.doi.org/10.1212/WNL.0000000000003147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047042PMC
September 2016

Modeled Fetal Risk of Genetic Diseases Identified by Expanded Carrier Screening.

JAMA 2016 Aug;316(7):734-42

Division of Reproductive Genetics, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1001/jama.2016.11139DOI Listing
August 2016

Neuropathic and Myopathic Pain.

Semin Pediatr Neurol 2016 08 14;23(3):242-247. Epub 2016 Oct 14.

Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL.

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http://dx.doi.org/10.1016/j.spen.2016.10.008DOI Listing
August 2016

Reactive oxygen species-activated nanomaterials as theranostic agents.

Nanomedicine (Lond) 2015 2;10(17):2709-23. Epub 2015 Sep 2.

Cardiovascular Institute, Beth Israel Deaconess Medical Center & Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.2217/nnm.15.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612518PMC
July 2016

Development of biomarker positivity analysis system for cancer diagnosis based on clinical data.

Biomed Mater Eng 2015 ;26 Suppl 1:S2101-11

Department of Industrial Engineering, Ajou University, 206 Worldcup-ro, Yeongtong-gu, Suwon, Korea.

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http://dx.doi.org/10.3233/BME-151516DOI Listing
July 2016

Sleep Pathology in Creutzfeldt-Jakob Disease.

J Clin Sleep Med 2016 07 15;12(7):1033-9. Epub 2016 Jul 15.

Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

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http://dx.doi.org/10.5664/jcsm.5944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918986PMC
July 2016

Evaluation of germline BRCA1 and BRCA2 mutations in a multi-ethnic Asian cohort of ovarian cancer patients.

Gynecol Oncol 2016 05 3;141(2):318-322. Epub 2015 Nov 3.

Cancer Research Malaysia, Subang Jaya, Malaysia; Breast Cancer Research Unit, University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258153017
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http://dx.doi.org/10.1016/j.ygyno.2015.11.001DOI Listing
May 2016

Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With Pembrolizumab.

J Clin Oncol 2016 05 7;34(13):1510-7. Epub 2016 Mar 7.

F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Wen-Jen Hwu, The University of Texas MD Anderson Cancer Center, Houston; Amita Patnaik, South Texas Accelerated Research Therapeutics, San Antonio, TX; Richard Kefford, Westmead Hospital, Melanoma Institute Australia, and Macquarie University; Peter Hersey, University of Sydney, Sydney, Australia; Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa; Richard Joseph, Mayo Clinic, Jacksonville, FL; Adil Daud, University of California San Francisco, San Francisco; Omid Hamid, The Angeles Clinic and Research Institute; Antoni Ribas, University of California Los Angeles, Los Angeles, CA; Caroline Robert, Gustave-Roussy and Paris-Sud University, Villejuif-Paris-Sud, France; Tara C. Gangadhar, Abramson Cancer Center, Philadelphia, PA; Anthony M. Joshua, Princess Margaret Hospital, Toronto, Ontario, Canada; Roxana Dronca, Mayo Clinic, Rochester, MN; Darcy Hille, Dahai Xue, Xiaoyun Nicole Li, S. Peter Kang, Scot Ebbinghaus, and Andrea Perrone, Merck, Kenilworth, NJ; and Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2015.64.0391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070547PMC
May 2016

Factors Associated with Acute and Chronic Hydrocephalus in Nonaneurysmal Subarachnoid Hemorrhage.

Neurocrit Care 2016 Feb;24(1):104-9

Neurocritical Care Section, Department of Neurology, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8111, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s12028-015-0152-7DOI Listing
February 2016

Variants in 6q25.1 Are Associated with Mammographic Density in Malaysian Chinese Women.

Cancer Epidemiol Biomarkers Prev 2016 Feb 16;25(2):327-33. Epub 2015 Dec 16.

Cancer Research Malaysia (formerly known as Cancer Research Initiatives Foundation), Subang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia. Breast Cancer Research Group, University Malaya Medical Centre, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0746DOI Listing
February 2016

p-Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia.

Biomaterials 2015 24;53:679-87. Epub 2015 Mar 24.

Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon, Gangwon-do 200-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.02.107DOI Listing
January 2016

Exaggerated hypertensive response to combretastatin A-4 phosphate in hypertensive rats: Effective pharmacological inhibition by diltiazem.

Vascul Pharmacol 2015 Nov 16;74:73-79. Epub 2015 May 16.

Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vph.2015.05.004DOI Listing
November 2015

Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury.

Sci Rep 2015 Nov 13;5:16592. Epub 2015 Nov 13.

Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, United States.

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http://dx.doi.org/10.1038/srep16592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643254PMC
November 2015

Endothelin A receptor antagonist, atrasentan, attenuates renal and cardiac dysfunction in Dahl salt-hypertensive rats in a blood pressure independent manner.

PLoS One 2015 16;10(3):e0121664. Epub 2015 Mar 16.

Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America; Department of BIN Fusion Technology, Chonbuk National University, Jeonju, South Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121664PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361570PMC
October 2015

PLIN2 inhibits insulin-induced glucose uptake in myoblasts through the activation of the NLRP3 inflammasome.

Int J Mol Med 2015 Sep 8;36(3):839-44. Epub 2015 Jul 8.

Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32610, USA.

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http://dx.doi.org/10.3892/ijmm.2015.2276DOI Listing
September 2015

Pembrolizumab.

J Immunother Cancer 2015 18;3:36. Epub 2015 Aug 18.

Department of Medical Oncology, Princess Margaret Cancer Centre, 610 University Avenue, Toronto, ON M5G 2M9 Canada.

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http://dx.doi.org/10.1186/s40425-015-0078-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539882PMC
August 2015

Anomalous transport on regular fracture networks: Impact of conductivity heterogeneity and mixing at fracture intersections.

Phys Rev E Stat Nonlin Soft Matter Phys 2015 Aug 28;92(2):022148. Epub 2015 Aug 28.

Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1103/PhysRevE.92.022148DOI Listing
August 2015

Advances in Muscular Dystrophies.

JAMA Neurol 2015 Jul;72(7):741-2

Center for Human Experimental Therapeutics, Departments of Neurology, Medicine, Pediatrics, and Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1001/jamaneurol.2014.4621DOI Listing
July 2015

Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin d signaling.

PLoS One 2014 30;9(9):e108382. Epub 2014 Sep 30.

Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108382PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182450PMC
June 2015

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

Authors:
Nick Orr Frank Dudbridge Nicola Dryden Sarah Maguire Daniela Novo Eleni Perrakis Nichola Johnson Maya Ghoussaini John L Hopper Melissa C Southey Carmel Apicella Jennifer Stone Marjanka K Schmidt Annegien Broeks Laura J Van't Veer Frans B Hogervorst Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Lorna Gibson Zoe Aitken Helen Warren Elinor Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Barbara Burwinkel Frederik Marme Andreas Schneeweiss Chistof Sohn Pascal Guénel Thérèse Truong Emilie Cordina-Duverger Marie Sanchez Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Javier Benitez Maria Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan L Neuhausen Hermann Brenner Aida Karina Dieffenbach Volker Arndt Christa Stegmaier Ute Hamann Hiltrud Brauch Christina Justenhoven Thomas Brüning Yon-Dschun Ko Heli Nevanlinna Kristiina Aittomäki Carl Blomqvist Sofia Khan Natalia Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Georgia Chenevix-Trench Jonathan Beesley Diether Lambrechts Matthieu Moisse Guiseppe Floris Benoit Beuselinck Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Paolo Radice Paolo Peterlongo Bernard Peissel Valeria Pensotti Fergus J Couch Janet E Olson Seth Slettedahl Celine Vachon Graham G Giles Roger L Milne Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Jacques Simard Mark S Goldberg France Labrèche Martine Dumont Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Wei Zheng Sandra Deming-Halverson Martha Shrubsole Jirong Long Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Peter Devilee Robertus A E M Tollenaar Caroline M Seynaeve Christi J Van Asperen Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Daniel Klevebring Maartje J Hooning Antoinette Hollestelle Carolien H M van Deurzen Mieke Kriege Per Hall Jingmei Li Jianjun Liu Keith Humphreys Angela Cox Simon S Cross Malcolm W R Reed Paul D P Pharoah Alison M Dunning Mitul Shah Barbara J Perkins Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Alan Ashworth Anthony Swerdlow Michael Jones Minouk J Schoemaker Alfons Meindl Rita K Schmutzler Curtis Olswold Susan Slager Amanda E Toland Drakoulis Yannoukakos Kenneth Muir Artitaya Lophatananon Sarah Stewart-Brown Pornthep Siriwanarangsan Keitaro Matsuo Hidema Ito Hiroji Iwata Junko Ishiguro Anna H Wu Chiu-Chen Tseng David Van Den Berg Daniel O Stram Soo Hwang Teo Cheng Har Yip Peter Kang Mohammad Kamran Ikram Xiao-Ou Shu Wei Lu Yu-Tang Gao Hui Cai Daehee Kang Ji-Yeob Choi Sue K Park Dong-Young Noh Mikael Hartman Hui Miao Wei Yen Lim Soo Chin Lee Suleeporn Sangrajrang Valerie Gaborieau Paul Brennan James Mckay Pei-Ei Wu Ming-Feng Hou Jyh-Cherng Yu Chen-Yang Shen William Blot Qiuyin Cai Lisa B Signorello Craig Luccarini Caroline Bayes Shahana Ahmed Mel Maranian Catherine S Healey Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot David J Hunter Sara Lindstrom Joe Dennis Kyriaki Michailidou Manjeet K Bolla Douglas F Easton Isabel dos Santos Silva Olivia Fletcher Julian Peto

Hum Mol Genet 2015 May 4;24(10):2966-84. Epub 2015 Feb 4.

Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406292PMC
May 2015

Outcome reliability in non-ambulatory boys/men with Duchenne muscular dystrophy.

Muscle Nerve 2015 Apr 11;51(4):522-32. Epub 2015 Feb 11.

Department of Neurology, Washington University School of Medicine in Saint Louis, St. Louis, Missouri, 63110, USA; Department of Pediatrics, Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1002/mus.24346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305351PMC
April 2015

Teaching Video NeuroImages: Movement of a paralyzed arm with yawning.

Neurology 2015 Apr;84(16):e118

From the Department of Neurology, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000001489DOI Listing
April 2015

Expanding the phenotypic spectrum and variability of endocrine abnormalities associated with TUBB3 E410K syndrome.

J Clin Endocrinol Metab 2015 Mar 5;100(3):E473-7. Epub 2015 Jan 5.

Harvard Reproductive Endocrine Sciences Center (R.B.), The Reproductive Endocrine Unit of the Department of Medicine (R.B.), Massachusetts General Hospital, Boston, Massachusetts 02114; Harvard Medical School (R.B., S.C., P.B.K., C.A., W.-M.C., E.C.E.), Boston, Massachusetts 02115; Department of Neurology (S.C., P.B.K., C.A., W.-M.C., E.C.E.), Kirby Neurobiology Center (S.C., C.A., W.-M.C., E.C.E.), and Department of Ophthalmology (S.E.M., E.C.E.), Boston Children's Hospital, Boston, Massachusetts 02115; and Howard Hughes Medical Institute (S.C., C.A., W.-M.C., E.C.E.), Chevy Chase, Maryland 20815.

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http://dx.doi.org/10.1210/jc.2014-4107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333039PMC
March 2015

A slowly progressive form of limb-girdle muscular dystrophy type 2C associated with founder mutation in the SGCG gene in Puerto Rican Hispanics.

Mol Genet Genomic Med 2015 Mar 8;3(2):92-8. Epub 2015 Jan 8.

Center for Gene Therapy and Paul D. Wellstone Muscular Dystrophy Research Center, Nationwide Children's Hospital Columbus, Ohio ; Department of Pediatrics and Neurology, The Ohio State University Columbus, Ohio ; Department of Pathology, Ohio State University and Nationwide Children's Hospital Columbus, Ohio.

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http://dx.doi.org/10.1002/mgg3.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367081PMC
March 2015

Evidence-based guideline summary: evaluation, diagnosis, and management of congenital muscular dystrophy: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the Practice Issues Review Panel of the American Association of Neuromuscular & Electrodiagnostic Medicine.

Neurology 2015 Mar;84(13):1369-78

From the Division of Pediatric Neurology (P.B.K.), University of Florida College of Medicine, Gainesville; Department of Neurology (P.B.K.), Boston Children's Hospital and Harvard Medical School, Boston, MA; Department of Neurology (L.M.), University of New Mexico, Albuquerque; Departments of Pediatrics and Neurology & Neurotherapeutics (S.T.I.), University of Texas Southwestern Medical Center, and Children's Medical Center, Dallas; Division of Critical Care Medicine (R.J.G.), Boston Children's Hospital, and Department of Anaesthesia, Harvard Medical School, Boston; Neuromuscular and Neurogenetic Disorders of Childhood Section (C.G.B.), Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD; Cure Congenital Muscular Dystrophy (Cure CMD) (A.R.), Olathe, KS; Department of Emergency Medicine (A.R.), Kaiser Permanente South Bay Medical Center, Harbor City, CA; Department of Physical Medicine & Rehabilitation (J.H.), University of Michigan, Ann Arbor; Departments of Neurology and Pediatrics (C.H.W.), School of Medicine, Stanford University, CA; Department of Neurology (C.H.W.), Driscoll Children's Hospital, Corpus Christi, TX; Murdoch Childrens Research Institute (K.N.), The Royal Children's Hospital, and University of Melbourne, Australia; Neurology & Neurosurgery (M.O.), McGill University, Montréal, Canada; Center for Health Policy (T.S.D.G., J.A.C., E.E.H.), American Academy of Neurology, Minneapolis, MN; Department of Neurology (G.G.), University of Kansas School of Medicine, Kansas City; and Department of Neurology (R.C.G.), University of Rochester Medical Center, NY.

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http://dx.doi.org/10.1212/WNL.0000000000001416DOI Listing
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March 2015

A new Mdr2(-/-) mouse model of sclerosing cholangitis with rapid fibrosis progression, early-onset portal hypertension, and liver cancer.

Am J Pathol 2015 Feb 2;185(2):325-34. Epub 2014 Dec 2.

Division of Gastroenterology and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.10.013DOI Listing
February 2015

POMK mutations disrupt muscle development leading to a spectrum of neuromuscular presentations.

Hum Mol Genet 2014 Nov 11;23(21):5781-92. Epub 2014 Jun 11.

Department of Pharmacology and Physiology and Integrative Systems Biology, The George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA,

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http://dx.doi.org/10.1093/hmg/ddu296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189906PMC
November 2014

Identifying diagnostic DNA methylation profiles for facioscapulohumeral muscular dystrophy in blood and saliva using bisulfite sequencing.

Clin Epigenetics 2014 29;6(1):23. Epub 2014 Oct 29.

The Wellstone Program & The Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655 USA ; The Department of Neurology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655 USA ; The Eunice Kennedy Shriver National Institute of Child Health and Human Development Sen. Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655 USA.

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http://dx.doi.org/10.1186/1868-7083-6-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232706PMC
November 2014

Silencing of drpr leads to muscle and brain degeneration in adult Drosophila.

Am J Pathol 2014 Oct 8;184(10):2653-61. Epub 2014 Aug 8.

Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts; Division of Pediatric Neurology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188861PMC
October 2014

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.

Sci Signal 2014 Oct 21;7(348):ra100. Epub 2014 Oct 21.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.2005262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300109PMC
October 2014

Reply: To PMID 23893312.

Muscle Nerve 2014 Sep 5;50(3):458-9. Epub 2014 Aug 5.

Division of Pediatric Neurology, University of Florida College of Medicine, Gainesville, Florida, USA.

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http://dx.doi.org/10.1002/mus.24317DOI Listing
September 2014

Observational study of spinal muscular atrophy type I and implications for clinical trials.

Neurology 2014 Aug 30;83(9):810-7. Epub 2014 Jul 30.

From the Departments of Neurology (R.S.F., A.R.F., M.L.Y.), Pediatrics (R.S.F., A. R.F., M.L.Y., M.B.), and Physical Therapy (A.M.G., J.F.),The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania (R.S.F., A.R.F., M.L.Y.), Philadelphia; Departments of Biostatistics and Computational Biology (M.P.M.) and Neurology (M.P.M., W.B.M.), University of Rochester, NY; Departments of Neurology (P.K., D.M.S., J. Montes, S.D., J.O., M.M., J. Marra, D.C.D.V.) and Pediatrics (W.K.C., D.M.S., P.A.R., D.C.D.V.), Columbia University, New York, NY; Departments of Neurology (B.T.D., P.B.K.) and Physical Therapy (J.Q., S.R.), Boston Children's Hospital, Harvard Medical School, Boston, MA; Department of Neurology (C.G.), University of South Florida, Tampa; and Departments of Neurology & Neurosurgery (M.O.) and Pediatrics (M.O.), McGill University, Montreal, Canada. R.S.F. is currently with the Division of Neurology, Nemours Children's Hospital, Orlando, FL. P.B.K. is currently with the Division of Pediatric Neurology, University of Florida College of Medicine, Gainesville, FL.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155049PMC
August 2014

Therapeutic use of H2O2-responsive anti-oxidant polymer nanoparticles for doxorubicin-induced cardiomyopathy.

Biomaterials 2014 Jul 22;35(22):5944-53. Epub 2014 Apr 22.

Department of BIN Fusion Technology, Chonbuk National University, Dukjin 664-14, Jeonju, Chonbuk 561-756, South Korea; Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, 3 Blackfan Circle, Boston, MA 02215, USA. Electronic address:

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July 2014

A differential for right iliac fossa pain and the importance of consenting properly.

BMJ Case Rep 2014 Mar 7;2014. Epub 2014 Mar 7.

Department of Breast Surgery, Glenfield Hospital, Leicester, UK.

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http://dx.doi.org/10.1136/bcr-2013-202282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948101PMC
March 2014