Publications by authors named "Peter J Richards"

29Publications

Role of HTRA1 in bone formation and regeneration: In vitro and in vivo evaluation.

PLoS One 2017 21;12(7):e0181600. Epub 2017 Jul 21.

Bone and Stem Cell Research Group, CABMM, University of Zurich, Zurich, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181600PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521800PMC
September 2017

Prostaglandin E inhibits matrix mineralization by human bone marrow stromal cell-derived osteoblasts via Epac-dependent cAMP signaling.

Sci Rep 2017 05 22;7(1):2243. Epub 2017 May 22.

Bone and Stem Cell Research Group, CABMM, University of Zurich, 8057, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41598-017-02650-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440379PMC
May 2017

Tailored Ahp-cyclodepsipeptides as Potent Non-covalent Serine Protease Inhibitors.

Angew Chem Int Ed Engl 2017 07 20;56(29):8555-8558. Epub 2017 Jun 20.

Chemical Biology, ZMB, University of Duisburg-Essen, Universitätsstr. 2, 45117, Essen, Germany.

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http://dx.doi.org/10.1002/anie.201701771DOI Listing
July 2017

Identification of Novel Equine (Equus caballus) Tendon Markers Using RNA Sequencing.

Genes (Basel) 2016 Nov 10;7(11). Epub 2016 Nov 10.

Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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http://www.mdpi.com/2073-4425/7/11/97
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http://dx.doi.org/10.3390/genes7110097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126783PMC
November 2016

Loss-of-Function of HtrA1 Abrogates All-Trans Retinoic Acid-Induced Osteogenic Differentiation of Mouse Adipose-Derived Stromal Cells Through Deficiencies in p70S6K Activation.

Stem Cells Dev 2016 05 11;25(9):687-98. Epub 2016 Apr 11.

1 Bone and Stem Cell Research Group, CABMM, University of Zurich , Zurich, Switzerland .

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http://dx.doi.org/10.1089/scd.2015.0368DOI Listing
May 2016

Novel Function of Serine Protease HTRA1 in Inhibiting Adipogenic Differentiation of Human Mesenchymal Stem Cells via MAP Kinase-Mediated MMP Upregulation.

Stem Cells 2016 06 16;34(6):1601-14. Epub 2016 Feb 16.

Bone and Stem Cell Research Group, CABMM, University of Zurich, Zurich, Switzerland.

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http://doi.wiley.com/10.1002/stem.2297
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http://dx.doi.org/10.1002/stem.2297DOI Listing
June 2016

Use of biomimetic microtissue spheroids and specific growth factor supplementation to improve tenocyte differentiation and adaptation to a collagen-based scaffold in vitro.

Biomaterials 2015 Nov 10;69:99-109. Epub 2015 Aug 10.

Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.08.013DOI Listing
November 2015

ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange.

Nucleic Acids Res 2015 Jan 1;43(1):129-42. Epub 2014 Dec 1.

Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, 8057 Zurich, Switzerland Competence Centre for Applied Biotechnology and Molecular Medicine, University of Zurich, 8057 Zurich, Switzerland Zurich Centre for Integrative Human Physiology (ZIHP), University of Zurich, 8057 Zurich, Switzerland

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http://dx.doi.org/10.1093/nar/gku1260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288160PMC
January 2015

Therapeutic potential of adipose-derived stromal cells in age-related osteoporosis.

Biomaterials 2014 Aug 2;35(26):7326-35. Epub 2014 Jun 2.

Bone and Stem Cell Research Group, CABMM, University of Zurich, 8057 Zurich, Switzerland; Institute of Physiology and Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.05.016DOI Listing
August 2014

Preparation and osteogenic differentiation of scaffold-free mouse adipose-derived stromal cell microtissue spheroids (ASC-MT).

Curr Protoc Stem Cell Biol 2013 Nov 13;27:Unit 2B.5.. Epub 2013 Nov 13.

Bone and Stem Cell Research Group, CABMM, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/9780470151808.sc02b05s27DOI Listing
November 2013

Assessment of the matrix degenerative effects of MMP-3, ADAMTS-4, and HTRA1, injected into a bovine intervertebral disc organ culture model.

Spine (Phila Pa 1976) 2013 Oct;38(22):E1377-87

*Institute for Surgical Technology and Biomechanics, University of Bern, Berne, Switzerland; †Bone and Stem Cell Research Group, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Zurich, Switzerland; and ‡Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/BRS.0b013e31829ffde8DOI Listing
October 2013

Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.

J Biol Chem 2012 Jun 3;287(25):21335-45. Epub 2012 May 3.

Bone and Stem Cell Research Group, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1074/jbc.M112.341032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375554PMC
June 2012

ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation.

FASEB J 2012 Jun 16;26(6):2631-8. Epub 2012 Mar 16.

Institute of Veterinary Biochemistry and Molecular Biology, University of Zürich, Winterthurerstrasse 190, Zürich 8057, Switzerland.

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http://dx.doi.org/10.1096/fj.11-200212DOI Listing
June 2012

Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice.

J Tissue Eng Regen Med 2012 May 28;6(5):378-90. Epub 2011 Jun 28.

Bone and Stem Cell Research Group, CABMM, University of Zürich, Winterthurerstrasse 190, Zurich, Switzerland.

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http://dx.doi.org/10.1002/term.440DOI Listing
May 2012

Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis.

Arthritis Rheum 2006 Jul;54(7):2084-95

Medical Biochemistry and Immunology, Tenovus Building, School of Medicine, Heath Park Campus, Cardiff University, Cardiff CF14 4XN, UK.

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http://doi.wiley.com/10.1002/art.21942
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http://dx.doi.org/10.1002/art.21942DOI Listing
July 2006

The role of human HtrA1 in arthritic disease.

J Biol Chem 2006 Mar 22;281(10):6124-9. Epub 2005 Dec 22.

School of Biosciences, Cardiff University, Cardiff CF10 3US, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M500361200
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http://dx.doi.org/10.1074/jbc.M500361200DOI Listing
March 2006

IL-6 transsignaling: the in vivo consequences.

J Interferon Cytokine Res 2005 May;25(5):241-53

Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, UK.

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http://dx.doi.org/10.1089/jir.2005.25.241DOI Listing
May 2005