Peter J Meikle

Peter J Meikle

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Peter J Meikle

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Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology.

Alzheimers Dement (Amst) 2019 Dec 5;11:619-627. Epub 2019 Sep 5.

Department of Psychiatry and Behavioral Sciences, Department of Medicine and the Duke Institute for Brain Sciences, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.dadm.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732667PMC
December 2019

Differential plasma postprandial lipidomic responses to krill oil and fish oil supplementations in women: A randomized crossover study.

Nutrition 2019 Sep 25;65:191-201. Epub 2019 Apr 25.

Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.nut.2019.03.021DOI Listing
September 2019

Dysferlin deficiency alters lipid metabolism and remodels the skeletal muscle lipidome in mice.

J Lipid Res 2019 Aug 15;60(8):1350-1364. Epub 2019 Jun 15.

Department of Physiology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia

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http://dx.doi.org/10.1194/jlr.M090845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672035PMC
August 2019

Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease.

Prog Lipid Res 2019 Aug 20:100993. Epub 2019 Aug 20.

Metabolomics Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Faculty of Medicine, Nursing and Health Sciences, Monash University, VIC 3800., Australia. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2019.100993DOI Listing
August 2019

Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease.

Prog Lipid Res 2019 04 8;74:186-195. Epub 2019 Apr 8.

Metabolomics Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Faculty of Medicine, Nursing and Health Sciences, Monash University, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2019.04.003DOI Listing
April 2019

Lipidomic profiling reveals early-stage metabolic dysfunction in overweight or obese humans.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 03 23;1864(3):335-343. Epub 2018 Dec 23.

Monash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, 43-51 Kanooka Grove, Clayton, VIC 3168, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13881981183024
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http://dx.doi.org/10.1016/j.bbalip.2018.12.014DOI Listing
March 2019

Changes in plasma lipidome following initiation of antiretroviral therapy.

PLoS One 2018 29;13(8):e0202944. Epub 2018 Aug 29.

Department of Infectious Diseases, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202944PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114786PMC
February 2019

Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance.

Cell Metab 2019 Jan 11;29(1):183-191.e7. Epub 2018 Oct 11.

Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, NSW 2010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183057
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http://dx.doi.org/10.1016/j.cmet.2018.09.013DOI Listing
January 2019

High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors.

Cell Chem Biol 2019 Jan 8;26(1):71-84.e4. Epub 2018 Nov 8.

Head Metabolomics Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia; Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2018.10.008DOI Listing
January 2019

Oleate disrupts cAMP signaling, contributing to potent stimulation of pancreatic β-cell autophagy.

J Biol Chem 2019 01 5;294(4):1218-1229. Epub 2018 Dec 5.

From the Division of Diabetes and Metabolism, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010,

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http://dx.doi.org/10.1074/jbc.RA118.004833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349129PMC
January 2019

Brown adipose tissue and lipid metabolism: New strategies for identification of activators and biomarkers with clinical potential.

Pharmacol Ther 2018 12 24;192:141-149. Epub 2018 Jul 24.

Metabolic and Vascular Physiology Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Central Clinical School, Monash University, Melbourne, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2018.07.002DOI Listing
December 2018

Plasma lipid species at type 1 diabetes onset predict residual beta-cell function after 6 months.

Metabolomics 2018 12 4;14(12):158. Epub 2018 Dec 4.

Baker IDI Heart and Diabetes Research Institute, 75 Commercial Road, Melbourne, Australia.

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http://dx.doi.org/10.1007/s11306-018-1456-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280838PMC
December 2018

Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression.

J Lipid Res 2018 10 24;59(10):1977-1986. Epub 2018 Jul 24.

Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands

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http://www.jlr.org/lookup/doi/10.1194/jlr.M085613
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http://dx.doi.org/10.1194/jlr.M085613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168306PMC
October 2018

Lipidomic Profiles of the Heart and Circulation in Response to Exercise versus Cardiac Pathology: A Resource of Potential Biomarkers and Drug Targets.

Cell Rep 2018 Sep;24(10):2757-2772

Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Department of Medicine, Monash University, Clayton, VIC 3800, Australia; Department of Diabetes, Central Clinical School, Monash University, Clayton, VIC 3800, Australia; Department of Physiology, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183127
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http://dx.doi.org/10.1016/j.celrep.2018.08.017DOI Listing
September 2018

Lipidomics Reveals a Tissue-Specific Fingerprint.

Front Physiol 2018 28;9:1165. Epub 2018 Aug 28.

Department of Experimental Medicine, Institute for Research in Biomedicine of Lleida, University of Lleida, Lleida, Spain.

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http://dx.doi.org/10.3389/fphys.2018.01165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121266PMC
August 2018

APP deficiency results in resistance to obesity but impairs glucose tolerance upon high fat feeding.

J Endocrinol 2018 06 19;237(3):311-322. Epub 2018 Apr 19.

Metabolic Research UnitSchool of Medicine and Centre for Molecular and Medical Research, Deakin University, Geelong, Victoria, Australia

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http://dx.doi.org/10.1530/JOE-18-0051DOI Listing
June 2018

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

Cell Metab 2018 May 19;27(5):1096-1110.e5. Epub 2018 Apr 19.

Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia; Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia; Faculty of Medicine, St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, NSW 2010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.03.014DOI Listing
May 2018

Lipidomic Profiles in Diabetes and Dementia.

J Alzheimers Dis 2017 ;59(2):433-444

Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3233/JAD-161215DOI Listing
April 2018

Lipidomic Profiling of Murine Macrophages Treated with Fatty Acids of Varying Chain Length and Saturation Status.

Metabolites 2018 Apr 23;8(2). Epub 2018 Apr 23.

Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia.

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http://dx.doi.org/10.3390/metabo8020029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027068PMC
April 2018

Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies.

Biochim Biophys Acta Mol Cell Biol Lipids 2018 Mar 6;1863(3):219-234. Epub 2017 Dec 6.

Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Department of Medicine, Monash University, Clayton, VIC 3800, Australia; Department of Physiology, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2017.12.003DOI Listing
March 2018

Weight Loss and Exercise Alter the High-Density Lipoprotein Lipidome and Improve High-Density Lipoprotein Functionality in Metabolic Syndrome.

Arterioscler Thromb Vasc Biol 2018 02 28;38(2):438-447. Epub 2017 Dec 28.

From the Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia (A.A.K., P.A.M., N.E.S., P.J.N., G.W., R.T., K.H., T.W.N., N.A.M., J.M.W., C.K.B., Z.H.A., G.W.L., B.A.K., P.J.M.); Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia (A.A.K., B.A.K., P.J.M.); Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia (A.A.K.); King Fahad Medical City, Riyadh, Saudi Arabia (Z.H.A.); and School of Biomedical Sciences, University of Western Australia, Perth (T.W.N.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310212DOI Listing
February 2018

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

J Lipid Res 2017 12 6;58(12):2275-2288. Epub 2017 Oct 6.

Lipidomics Core Facility and Department of Pathology, Wayne State University, Detroit, MI.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M079012
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http://dx.doi.org/10.1194/jlr.M079012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711491PMC
December 2017

Baseline serum phosphatidylcholine plasmalogen concentrations are inversely associated with incident myocardial infarction in patients with mixed peripheral artery disease presentations.

Atherosclerosis 2017 08 29;263:301-308. Epub 2017 Jun 29.

The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, James Cook University, Townsville, Queensland, Australia; The Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, Queensland, Australia; Department of Vascular and Endovascular Surgery, The Townsville Hospital, Townsville, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.06.925DOI Listing
August 2017

Immunometabolic and Lipidomic Markers Associated With the Frailty Index and Quality of Life in Aging HIV+ Men on Antiretroviral Therapy.

EBioMedicine 2017 Aug 18;22:112-121. Epub 2017 Jul 18.

Department of Infectious Diseases, The Alfred and Monash University, Level 2, Burnet Institute, 85 Commercial Road, Melbourne, VIC 3004, Australia; Burnet Institute, 85 Commercial Road, Melbourne, VIC 3004, Australia; Department of Microbiology and Immunology, University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552224PMC
August 2017

Changes in Lipids and Inflammatory Markers after Consuming Diets High in Red Meat or Dairy for Four Weeks.

Nutrients 2017 Aug 17;9(8). Epub 2017 Aug 17.

Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia.

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http://dx.doi.org/10.3390/nu9080886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579679PMC
August 2017

Platelet lipidomics: a window of opportunity to assess cardiovascular risk?

Eur Heart J 2017 07;38(25):2006-2008

Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.

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http://dx.doi.org/10.1093/eurheartj/ehx258DOI Listing
July 2017

The Effects of Long-Term Saturated Fat Enriched Diets on the Brain Lipidome.

PLoS One 2016 1;11(12):e0166964. Epub 2016 Dec 1.

Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166964PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132325PMC
June 2017

Differential regulation of sphingolipid metabolism in plasma, hippocampus, and cerebral cortex of mice administered sphingolipid modulating agents.

J Neurochem 2017 05 28;141(3):413-422. Epub 2017 Feb 28.

Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1111/jnc.13964DOI Listing
May 2017

Association between dairy intake, lipids and vascular structure and function in diabetes.

World J Diabetes 2017 May;8(5):202-212

Kristina S Petersen, Jennifer B Keogh, Natalie Lister, Peter M Clifton, School of Pharmacy and Medical Sciences and Sansom Institute for Health Research, University of South Australia, Adelaide, SA 5000, Australia.

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http://dx.doi.org/10.4239/wjd.v8.i5.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437618PMC
May 2017

Serum phosphatidylinositol as a biomarker for bipolar disorder liability.

Bipolar Disord 2017 03 23;19(2):107-115. Epub 2017 Feb 23.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1111/bdi.12468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798864PMC
March 2017

Sphingolipids and phospholipids in insulin resistance and related metabolic disorders.

Nat Rev Endocrinol 2017 02 21;13(2):79-91. Epub 2016 Oct 21.

Department of Nutrition and Integrative Physiology, University of Utah, 201 Presidents Circle, Salt Lake City, Utah, 84112, USA.

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http://dx.doi.org/10.1038/nrendo.2016.169DOI Listing
February 2017

Markers of sympathetic nervous system activity associate with complex plasma lipids in metabolic syndrome subjects.

Atherosclerosis 2017 01 1;256:21-28. Epub 2016 Dec 1.

Baker IDI Heart & Diabetes Institute, Melbourne, Australia; Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.11.032DOI Listing
January 2017

Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes: A cross-sectional study.

World J Diabetes 2017 Jan;8(1):18-27

Kristina S Petersen, Jennifer B Keogh, Peter M Clifton, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia.

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http://dx.doi.org/10.4239/wjd.v8.i1.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237814PMC
January 2017

Plasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes Mellitus.

Circulation 2016 Nov 18;134(21):1637-1650. Epub 2016 Oct 18.

From Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia (Z.H.A., P.A.M., C.K.B., N.A.M., G.W., P.J.N., B.A.K., P.J.M.); King Fahad Medical City, Riyadh, Saudi Arabia (Z.H.A.); Department of Biochemistry and Molecular Biology, University of Melbourne, Melbourne, VIC, Australia (Z.H.A., M.J.M., P.J.M.); NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia (J.S., E.H.B.); School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia (A.M.T., S.Z.); Royal Prince Alfred Hospital, Sydney, NSW, Australia (D.R.S.); Hópital Bichat-Claude Bernard and Université Paris 7, Paris, France (M.M.); George Institute for Global Health, Sydney, NSW, Australia (B.N., N.R.P., S.Z., G.S.H., J.C., M.W.); University College London and National Institute for Health Research, University College London Hospitals, Biomedical Research Centre, London, UK (B.W.); Department of Cardiology, Royal Perth Hospital/University of Western Australia, Perth, WA, Australia (G.S.H.); George Institute for Global Health, University of Oxford, Oxford, UK (M.W.); and Department of Epidemiology, Johns Hopkins University, Baltimore, MD (M.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023233DOI Listing
November 2016

Corrigendum to "Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice" [Atherosclerosis 243/2 (2015) 598-608].

Atherosclerosis 2016 11;254:314-315

Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.01.046DOI Listing
November 2016

Lipidomic analyses in epidemiology.

Int J Epidemiol 2016 10 10;45(5):1329-1338. Epub 2016 Jun 10.

Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia and

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http://dx.doi.org/10.1093/ije/dyw112DOI Listing
October 2016

Drug induced exocytosis of glycogen in Pompe disease.

Biochem Biophys Res Commun 2016 Oct 28;479(4):721-727. Epub 2016 Sep 28.

Mechanisms in Cell Biology and Diseases Research Group, School of Pharmacy and Medical Science, Division of Health Sciences, University of South Australia, Adelaide 5001, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.09.145DOI Listing
October 2016

Strategies for Extending Metabolomics Studies with Stable Isotope Labelling and Fluxomics.

Metabolites 2016 Oct 1;6(4). Epub 2016 Oct 1.

Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.3390/metabo6040032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192438PMC
October 2016

Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia.

Arterioscler Thromb Vasc Biol 2016 07 5;36(7):1338-49. Epub 2016 May 5.

From the ANZAC Research Institute (M.K., D.N., W.J., L.K.) and Department of Cardiology (L.K.), Concord Hospital, University of Sydney, Sydney, Australia; Centre for Vascular Research (E.G., C.Q.) and Department of Pathology (B.L.), University of New South Wales, Sydney, Australia; Baker IDI Heart and Diabetes Institute, Melbourne, Australia (T.W.N., P.J.M.); Department of Medicine, Division Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands (J.F.P.B., P.C.N.R.); Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Australia (V.D.); Lipid Research Group, School of Medical Sciences, University of New South Wales Australia, Sydney, Australia (K.-A.R.).

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http://dx.doi.org/10.1161/ATVBAHA.115.307030DOI Listing
July 2016

A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmalogens.

Mol Metab 2016 Jun 13;5(6):404-414. Epub 2016 Apr 13.

Diabetes and Metabolism Division, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia; St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877660PMC
June 2016

Circulating Lipids Are Associated with Alcoholic Liver Cirrhosis and Represent Potential Biomarkers for Risk Assessment.

PLoS One 2015 24;10(6):e0130346. Epub 2015 Jun 24.

Discipline of Clinical Medicine & Addiction Medicine, Faculty of Medicine, University of Sydney, Sydney, NSW 2006, Australia; Drug Health Services and Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130346PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479371PMC
April 2016

Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans.

Obesity (Silver Spring) 2016 Apr 24;24(4):908-16. Epub 2016 Feb 24.

Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/oby.21448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585800PMC
April 2016

High density lipoprotein efficiently accepts surface but not internal oxidised lipids from oxidised low density lipoprotein.

Biochim Biophys Acta 2016 Feb 10;1861(2):69-77. Epub 2015 Nov 10.

Metabolomics Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia; Department of Biochemistry and Molecular Biology, Faculty of Medicine, Dentistry, and Health Sciences, The University of Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2015.11.002DOI Listing
February 2016

Zebrafish Embryonic Lipidomic Analysis Reveals that the Yolk Cell Is Metabolically Active in Processing Lipid.

Cell Rep 2016 Feb 4;14(6):1317-1329. Epub 2016 Feb 4.

Metabolic Genetic Diseases Laboratory, Metabolic Research Unit, Deakin University School of Medicine, 75 Pigdons Road, Geelong, VIC 3216, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.01.016DOI Listing
February 2016

Statin action favors normalization of the plasma lipidome in the atherogenic mixed dyslipidemia of MetS: potential relevance to statin-associated dysglycemia.

J Lipid Res 2015 Dec 20;56(12):2381-92. Epub 2015 Oct 20.

Dyslipidemia and Atherosclerosis Research Unit, INSERM UMR-S939, and University of Pierre and Marie Curie, Pitie-Salpetriere University Hospital, Paris, France.

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http://dx.doi.org/10.1194/jlr.P061143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655992PMC
December 2015

Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice.

Atherosclerosis 2015 Dec 26;243(2):598-608. Epub 2015 Oct 26.

Baker IDI Heart and Diabetes Institute, Melbourne, VIC, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.10.096DOI Listing
December 2015

Postprandial Plasma Phospholipids in Men Are Influenced by the Source of Dietary Fat.

J Nutr 2015 Sep 15;145(9):2012-8. Epub 2015 Jul 15.

Metabolomics Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia; and.

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http://dx.doi.org/10.3945/jn.115.210104DOI Listing
September 2015

The prediction of type 2 diabetes in women with previous gestational diabetes mellitus using lipidomics.

Diabetologia 2015 Jul 17;58(7):1436-42. Epub 2015 Apr 17.

Obstetrics, Nutrition and Endocrinology Group, Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Level 4/163 Studley Road, Heidelberg, 3084, VIC, Australia,

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http://dx.doi.org/10.1007/s00125-015-3587-7DOI Listing
July 2015

Lipidomic Profiling in Inflammatory Bowel Disease: Comparison Between Ulcerative Colitis and Crohn's Disease.

Inflamm Bowel Dis 2015 Jul;21(7):1511-8

*Baker IDI Heart and Diabetes Institute, Melbourne, Australia; †Department of Cardiovascular Medicine, The Alfred Hospital, Melbourne, Australia; ‡Department of Cardiovascular Medicine, The First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, China; and §Departments of Gastroenterology, The Alfred Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1097/MIB.0000000000000394DOI Listing
July 2015

Association of Plasma Ceramides and Sphingomyelin With VLDL apoB-100 Fractional Catabolic Rate Before and After Rosuvastatin Treatment.

J Clin Endocrinol Metab 2015 Jun 27;100(6):2497-501. Epub 2015 Mar 27.

Metabolic Research Centre (T.W.K.N., E.M.M.O., G.F.W., D.C.C., P.H.R.B.), School of Medicine and Pharmacology, University of Western Australia and Lipid Disorders Clinic (G.F.W.), Department of Cardiovascular Medicine, Royal Perth Hospital, Faculty of Engineering, Computing, and Mathematics (P.H.R.B.), University of Western Australia, Perth, Western Australia 6847, Australia; and Metabolomics Laboratory (T.W.K.N., P.J.M.), Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1210/jc.2014-4348DOI Listing
June 2015

An Efficient Single Phase Method for the Extraction of Plasma Lipids.

Metabolites 2015 Jun 17;5(2):389-403. Epub 2015 Jun 17.

Baker IDI, Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.

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http://dx.doi.org/10.3390/metabo5020389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495379PMC
June 2015

Absence of α-galactosidase cross-correction in Fabry heterozygote cultured skin fibroblasts.

Mol Genet Metab 2015 Feb 12;114(2):268-73. Epub 2014 Nov 12.

Baker IDI Heart and Diabetes Institute, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.ymgme.2014.11.005DOI Listing
February 2015

Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis.

Hum Mol Genet 2015 Jan 10;24(2):436-49. Epub 2014 Sep 10.

Department of Biochemistry and Molecular Biology Department of Anatomy and Developmental Biology, Monash University, Wellington Road, Clayton, VIC 3800, Australia

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http://hmg.oxfordjournals.org/content/early/2014/09/19/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu459
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http://dx.doi.org/10.1093/hmg/ddu459DOI Listing
January 2015

Short term fat feeding rapidly increases plasma insulin but does not result in dyslipidaemia.

Front Physiol 2014 2;5:469. Epub 2014 Dec 2.

Neuropharmacology Laboratory, BakerIDI Heart and Diabetes Institute Melbourne, VIC, Australia ; Department of Pharmacology, Monash University Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fphys.2014.00469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251291PMC
December 2014

Dose-dependent effects of rosuvastatin on the plasma sphingolipidome and phospholipidome in the metabolic syndrome.

J Clin Endocrinol Metab 2014 Nov 20;99(11):E2335-40. Epub 2014 Aug 20.

Metabolic Research Centre (T.W.K.N., E.M.M.O., G.F.W., D.C.C., P.H.R.B.), School of Medicine and Pharmacology, and Faculty of Engineering (P.H.R.B.), Computing and Mathematics, Perth, Western Australia, Australia; and Metabolomics Laboratory (T.W.K.N., J.M.W., P.J.M.), Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1210/jc.2014-1665DOI Listing
November 2014

Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages.

J Biol Chem 2014 Nov 6;289(47):32895-913. Epub 2014 Oct 6.

From the Atherosclerosis Laboratory, ANZAC Research Institute, University of Sydney, Sydney, New South Wales 2139, the Department of Cardiology, Concord Repatriation General Hospital, Concord, New South Wales 2139, Australia.

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http://dx.doi.org/10.1074/jbc.M114.612341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239637PMC
November 2014

LICRE: unsupervised feature correlation reduction for lipidomics.

Bioinformatics 2014 Oct 13;30(19):2832-3. Epub 2014 Jun 13.

Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia and Department of Computing and Information Systems, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1093/bioinformatics/btu381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173018PMC
October 2014

PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle.

Mol Metab 2014 Sep 14;3(6):652-63. Epub 2014 Jun 14.

Biology of Lipid Metabolism Laboratory, Department of Physiology, Monash University, Clayton, Victoria, 3800, Australia.

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http://dx.doi.org/10.1016/j.molmet.2014.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142393PMC
September 2014

Plasma lipidomic analysis predicts non-calcified coronary artery plaque in asymptomatic patients at intermediate risk of coronary artery disease.

Eur Heart J Cardiovasc Imaging 2014 Aug 11;15(8):908-16. Epub 2014 Mar 11.

Heart Centre, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia Baker IDI Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC 3004, Australia.

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http://dx.doi.org/10.1093/ehjci/jeu033DOI Listing
August 2014

Lipidomics: potential role in risk prediction and therapeutic monitoring for diabetes and cardiovascular disease.

Pharmacol Ther 2014 Jul 6;143(1):12-23. Epub 2014 Feb 6.

Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.pharmthera.2014.02.001DOI Listing
July 2014

Comparison of the serum lipidome in patients with abdominal aortic aneurysm and peripheral artery disease.

Circ Cardiovasc Genet 2014 Feb 21;7(1):71-9. Epub 2014 Jan 21.

The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, James Cook University, Townsville, Queensland, Australia.

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000343DOI Listing
February 2014

Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells.

Diabetologia 2014 Jan 23;57(1):129-39. Epub 2013 Oct 23.

Diabetes and Obesity Department, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s00125-013-3083-xDOI Listing
January 2014

Alteration of endoplasmic reticulum lipid rafts contributes to lipotoxicity in pancreatic β-cells.

J Biol Chem 2013 Sep 29;288(37):26569-82. Epub 2013 Jul 29.

From the Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria St., Darlinghurst, New South Wales 2010, Australia and.

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http://dx.doi.org/10.1074/jbc.M113.489310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772204PMC
September 2013