Peter H Howarth

Peter H Howarth

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Peter H Howarth

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Genome-Wide Posttranscriptional Dysregulation by MicroRNAs in Human Asthma as Revealed by Frac-seq.

J Immunol 2018 07 16;201(1):251-263. Epub 2018 May 16.

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1701798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013048PMC
July 2018

IL-1α mediates cellular cross-talk in the airway epithelial mesenchymal trophic unit.

Tissue Barriers 2016 Jul-Sep;4(3):e1206378. Epub 2016 Jun 28.

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, University Hospital Southampton, Southampton, UK; NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK; Institute for Life Sciences, Highfield Campus, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1080/21688370.2016.1206378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993579PMC
February 2018

Asthma Exacerbations Associated with Lung Function Decline in Patients with Severe Eosinophilic Asthma.

J Allergy Clin Immunol Pract 2018 May - Jun;6(3):980-986.e1. Epub 2018 Feb 15.

Research and Development, GSK, Stockley Park, Middlesex, United Kingdom; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and NIHR Respiratory Biomedical Research Unit, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaip.2017.12.019DOI Listing
February 2018

Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.

Antioxid Redox Signal 2017 Dec 26;27(18):1460-1472. Epub 2017 Jun 26.

1 Ludwig Boltzmann Institute for Lung Vascular Research , Graz, Austria .

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http://dx.doi.org/10.1089/ars.2016.6863DOI Listing
December 2017

Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma.

PLoS One 2017 3;12(1):e0168680. Epub 2017 Jan 3.

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168680PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207492PMC
August 2017

Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses.

PLoS One 2016 21;11(4):e0153926. Epub 2016 Apr 21.

Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton General Hospital, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153926PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839664PMC
September 2016

Response.

Chest 2016 08;150(2):474

Clinical and Experimental Sciences University of Southampton and Southampton General Hospital, Southampton, England; Southampton NIHR Respiratory Biomedical Research Unit, Southampton Centre for Biomedical Research, University Hospital Southampton NHS Foundation Trust, Southampton, England.

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http://dx.doi.org/10.1016/j.chest.2016.05.033DOI Listing
August 2016

Toll-like Receptor 7 Is Reduced in Severe Asthma and Linked to an Altered MicroRNA Profile.

Am J Respir Crit Care Med 2016 07;194(1):26-37

1 Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201502-0280OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960627PMC
July 2016

Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1.

J Allergy Clin Immunol 2016 07 3;138(1):61-75. Epub 2016 Feb 3.

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, Southampton, United Kingdom; NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2015.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929135PMC
July 2016

Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life.

JCI Insight 2016 Jul;1(11)

The Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; National Institute for Health Research (NIHR) Southampton Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.; Institute for Life Sciences, Stem Cells and Regeneration, Human Genetics, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1172/jci.insight.87632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968941PMC
July 2016

Airway Surfactant Protein D Deficiency in Adults With Severe Asthma.

Chest 2016 05 13;149(5):1165-72. Epub 2016 Jan 13.

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton General Hospital, Southampton, UK; Southampton NIHR Respiratory Biomedical Research Unit, Southampton Centre for Biomedical Research, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1016/j.chest.2015.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944769PMC
May 2016

Common airborne fungi induce species-specific effects on upper airway inflammatory and remodelling responses.

Rhinology 2016 Mar;54(1):51-5

Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.4193/Rhin14.278DOI Listing
March 2016

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

Eur Respir J 2016 Mar 11;47(3):783-91. Epub 2016 Feb 11.

Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK.

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http://dx.doi.org/10.1183/13993003.00171-2015DOI Listing
March 2016

A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells.

PLoS One 2014 31;9(10):e111659. Epub 2014 Oct 31.

Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton General Hospital, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111659PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216117PMC
December 2015

Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma.

PLoS One 2014 23;9(6):e100645. Epub 2014 Jun 23.

Academic Unit of Clinical and Experimental Sciences; NIHR Respiratory Biomedical Research Unit, University of Southampton Faculty of Medicine, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100645PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067344PMC
November 2015

Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms.

J Allergy Clin Immunol 2015 Aug 5;136(2):323-33. Epub 2015 Mar 5.

Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, Southampton, United Kingdom; NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom. Electronic address:

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https://www.researchgate.net/profile/Borislav_D_Dimitrov/pub
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http://linkinghub.elsevier.com/retrieve/pii/S009167491500104
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http://dx.doi.org/10.1016/j.jaci.2015.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534770PMC
August 2015

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

Eur Respir J 2015 Jun 5;45(6):1745-8. Epub 2015 Mar 5.

Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK.

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http://dx.doi.org/10.1183/09031936.00206514DOI Listing
June 2015

The effects on bronchial epithelial mucociliary cultures of coarse, fine, and ultrafine particulate matter from an underground railway station.

Toxicol Sci 2015 May 10;145(1):98-107. Epub 2015 Feb 10.

*Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton SO16 6YD, United Kingdom, Institute for Life Sciences, Highfield Campus, University of Southampton, Southampton SO17 1BJ, United Kingdom, Ocean and Earth Science, National Oceanography Centre Southampton, University of Southampton, Southampton SO14 3ZH, United Kingdom, NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton SO16 6YD, United Kingdom, Centre for Sustainability, Environment, and Health, National Institute for Public Health and the Environment (RIVM), 3720BA Bilthoven, The Netherlands and Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3508TC Utrecht, The Netherlands *Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton SO16 6YD, United Kingdom, Institute for Life Sciences, Highfield Campus, University of Southampton, Southampton SO17 1BJ, United Kingdom, Ocean and Earth Science, National Oceanography Centre Southampton, University of Southampton, Southampton SO14 3ZH, United Kingdom, NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton SO16 6YD, United Kingdom, Centre for Sustainability, Environment, and Health, National Institute for Public Health and the Environment (RIVM), 3720BA Bilthoven, The Netherlands and Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3508TC Utrecht, The Netherlands *Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton SO16 6YD, United Kingdom, Institute for Life Sciences, Highfield Campus, University of Southampton, Southampton SO17 1BJ, United Kingdom, Ocean and Earth Science, National Oceanography Centre Southampton, University of Southampton, Southampton SO14 3ZH, United K

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http://dx.doi.org/10.1093/toxsci/kfv034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408962PMC
May 2015

Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation.

J Mech Behav Biomed Mater 2014 Nov 15;39:9-26. Epub 2014 Jul 15.

Bioengineering Science Research Group, Faculty of Engineering and the Environment, University of Southampton, SO17 1BJ Southampton, UK; Institute for Lightweight Design and Structural Biomechanics, Faculty of Engineering and the Environment, Vienna University of Technology, Gusshausstrasse 27-29, Vienna 1040, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jmbbm.2014.06.015DOI Listing
November 2014

Barrier disrupting effects of alternaria alternata extract on bronchial epithelium from asthmatic donors.

PLoS One 2013 23;8(8):e71278. Epub 2013 Aug 23.

Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, South Block, University Hospital Southampton, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071278PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751915PMC
April 2014

Sensitization via healthy skin programs Th2 responses in individuals with atopic dermatitis.

J Invest Dermatol 2013 Oct 25;133(10):2372-2380. Epub 2013 Mar 25.

Sir Henry Wellcome Laboratories, Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton General Hospital, Southampton, UK. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.148DOI Listing
October 2013

TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation.

J Allergy Clin Immunol 2013 Sep 28;132(3):665-675.e8. Epub 2013 Apr 28.

Academic Unit of Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom; Southampton NIHR Respiratory Biomedical Research Unit, Sir Henry Wellcome Laboratories, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.03.005DOI Listing
September 2013

Barrier responses of human bronchial epithelial cells to grass pollen exposure.

Eur Respir J 2013 Jul 8;42(1):87-97. Epub 2012 Nov 8.

Brooke Laboratory, Clinical and Experimental Sciences, Faculty of Medicine, University Hospital Southampton, Southampton, UK.

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http://dx.doi.org/10.1183/09031936.00075612DOI Listing
July 2013

Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response.

PLoS One 2012 6;7(9):e44580. Epub 2012 Sep 6.

Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044580PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435262PMC
March 2013

Airway remodelling in asthma and novel therapy.

Asian Pac J Allergy Immunol 2013 Mar;31(1):3-10

Department of Pediatrics, Mahidol University, Bangkok, Thailand.

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March 2013

Evaluation of a rapid lateral flow immunoassay for Staphylococcus aureus detection in respiratory samples.

Diagn Microbiol Infect Dis 2013 Jan 25;75(1):28-36. Epub 2012 Oct 25.

Institute of Pharmaceutical Science, King's College London, London SE1 9NH, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S07328893120038
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http://dx.doi.org/10.1016/j.diagmicrobio.2012.09.011DOI Listing
January 2013

Salbutamol but not ipratropium abolishes leukotriene D4-induced gas exchange abnormalities in asthma.

Eur J Clin Pharmacol 2012 Oct 29;68(10):1375-83. Epub 2012 Mar 29.

Lung and Allergy Clinic, Department of Medicine at Karolinska University Hospital Huddinge and The Centre for Allergy Research, Karolinska Institutet, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00228-012-1256-zDOI Listing
October 2012

Resistin-like molecule-β is induced following bronchoconstriction of asthmatic airways.

Respirology 2012 Oct;17(7):1094-100

Academic Unit of Clinical and Experimental Sciences, Southampton University Faculty of Medicine, NIHR Respiratory Biomedical Research Unit and Wellcome Trust Clinical Research Facility, Southampton, UK.

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http://dx.doi.org/10.1111/j.1440-1843.2012.02215.xDOI Listing
October 2012

Thin film polycrystalline silicon nanowire biosensors.

Nano Lett 2012 Apr 26;12(4):1868-72. Epub 2012 Mar 26.

School of Electronics & Computer Science, University of Southampton, Southampton, SO17 1BJ, UK.

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http://dx.doi.org/10.1021/nl2042276DOI Listing
April 2012

A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis.

Respirology 2012 Feb;17(2):342-9

Division of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, Hampshire, UK.

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http://dx.doi.org/10.1111/j.1440-1843.2011.02098.xDOI Listing
February 2012

Characterization of bacterial community diversity in chronic rhinosinusitis infections using novel culture-independent techniques.

Am J Rhinol Allergy 2011 Jul-Aug;25(4):e133-40

Molecular Microbiology Research Laboratory, Pharmaceutical Science Division, Franklin-Wilkins Building, King's College London, London, United Kingdom, UK.

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http://dx.doi.org/10.2500/ajra.2011.25.3628DOI Listing
December 2011

Airway inflammation in atopic patients: a comparison of the upper and lower airways.

Otolaryngol Head Neck Surg 2011 Sep 20;145(3):396-400. Epub 2011 May 20.

School of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1177/0194599811410531DOI Listing
September 2011

Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation.

Am J Respir Crit Care Med 2011 Aug;184(4):421-9

Perinatal Institute, Divisions of Neonatology, Perinatal, and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1164/rccm.201101-0106OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175541PMC
August 2011

Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus.

J Allergy Clin Immunol 2011 May 16;127(5):1148-54.e9. Epub 2011 Feb 16.

Division of Infection, Inflammation and Immunity, University of Southampton School of Medicine and National Institute for Health Research Respiratory Biomedical Research Unit, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2011.01.023DOI Listing
May 2011

Effect of bronchoconstriction on airway remodeling in asthma.

N Engl J Med 2011 05;364(21):2006-15

Division of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa1014350DOI Listing
May 2011

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma.

Thorax 2010 Jul;65(7):626-32

The Brooke Laboratories, Sir Henry Wellcome Laboratories, South Block, Southampton General Hospital, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1136/thx.2009.125930DOI Listing
July 2010

Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients.

J Immunol 2010 Apr 17;184(8):4568-74. Epub 2010 Mar 17.

Division of Infection, Southampton National Institute of Health Research Respiratory Biomedical Research Unit, University of Southampton School of Medicine, Southampton, United Kingdom.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0901342
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http://dx.doi.org/10.4049/jimmunol.0901342DOI Listing
April 2010

The role of the airway epithelium and its interaction with environmental factors in asthma pathogenesis.

Proc Am Thorac Soc 2009 Dec;6(8):655-9

Infection, Inflammation and Immunity Division, School of Medicine, Southampton University, Southampton General Hospital, Southampton SO166YD, UK.

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http://dx.doi.org/10.1513/pats.200907-072DPDOI Listing
December 2009

A new look at the pathogenesis of asthma.

Clin Sci (Lond) 2009 Dec 23;118(7):439-50. Epub 2009 Dec 23.

University of Southampton, Southampton General Hospital, UK.

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http://dx.doi.org/10.1042/CS20090474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805922PMC
December 2009

The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.

J Allergy Clin Immunol 2008 Jun 14;121(6):1400-6, 1406.e1-4. Epub 2008 Apr 14.

Division of Infection, Inflammation, and Repair, School of Medicine, Southampton General Hospital, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2008.03.003DOI Listing
June 2008

Elevation of Candida IgG antibodies in patients with medically unexplained symptoms.

J Altern Complement Med 2007 Dec;13(10):1129-33

School of Medicine, Community Clinical Sciences Research Division, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, United Kingdom.

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http://dx.doi.org/10.1089/acm.2007.0568DOI Listing
December 2007

Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities.

J Allergy Clin Immunol 2006 Mar;117(3):496-506; quiz 507

Division of Infection, Inflammation and Repair, School of Medicine, University of Southampton, Southampton General Hospital, UK.

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http://dx.doi.org/10.1016/j.jaci.2006.01.039DOI Listing
March 2006

ADAM33 expression in asthmatic airways and human embryonic lungs.

Am J Respir Crit Care Med 2005 May 11;171(9):958-65. Epub 2005 Feb 11.

Roger Brooke Laboratories, Division of Infection, Inflammation, and Repair, and Human Genetics Division, School of Medicine, University of Southampton, Southampton General Hospital, United Kingdom.

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http://dx.doi.org/10.1164/rccm.200409-1251OCDOI Listing
May 2005

Preface to outcome measures in allergic rhinitis.

J Allergy Clin Immunol 2005 Mar;115(3 Suppl 1):S387-9

IIR Research Division, Mail Point 810, Southampton General Hospital, Tremona Road, Southampton, Hampshire, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2004.12.017DOI Listing
March 2005

Clinical outcomes and adverse effect monitoring in allergic rhinitis.

J Allergy Clin Immunol 2005 Mar;115(3 Suppl 1):S390-413

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1016/j.jaci.2004.12.014DOI Listing
March 2005

Objective monitoring of nasal airway inflammation in rhinitis.

J Allergy Clin Immunol 2005 Mar;115(3 Suppl 1):S414-41

IIR Research Division, Mail Point 810, Southampton General Hospital, Tremona Road, Southampton, Hampshire, SO16 6YD, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2004.12.1134DOI Listing
March 2005

Objective monitoring of nasal patency and nasal physiology in rhinitis.

J Allergy Clin Immunol 2005 Mar;115(3 Suppl 1):S442-59

Asthma and Allergy Associates, 2709 North Tejon, Colorado Springs, CO 80907, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009167490403271
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http://dx.doi.org/10.1016/j.jaci.2004.12.015DOI Listing
March 2005

Nasal mucosal immunoexpression of the mast cell chemoattractants TGF-beta, eotaxin, and stem cell factor and their receptors in allergic rhinitis.

J Allergy Clin Immunol 2004 Oct;114(4):799-806

Department of Respiratory Cell and Molecular Biology, Division of Asthma, Allergy and Inflammation, School of Medicine, University of Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2004.07.010DOI Listing
October 2004

Synthetic responses in airway smooth muscle.

J Allergy Clin Immunol 2004 Aug;114(2 Suppl):S32-50

Respiratory Cell and Molecular Biology, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2004.04.041DOI Listing
August 2004

Induction of the epidermal growth factor receptor and its ligands in nasal epithelium by ozone.

J Allergy Clin Immunol 2004 Jan;113(1):120-6

Respiratory Cell and Moleculat Biology Division, School of Medicine, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2003.09.040DOI Listing
January 2004

Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium.

Am J Respir Cell Mol Biol 2003 Jan;28(1):61-8

The Brooke Laboratory, Division of Infection, Inflammation and Repair, School of Medicine, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1165/rcmb.4715DOI Listing
January 2003

Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis.

Am J Respir Cell Mol Biol 2002 Aug;27(2):179-85

School of Medicine, University of Southampton, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1165/ajrcmb.27.2.4699DOI Listing
August 2002

Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects.

J Allergy Clin Immunol 2002 Jan;109(1):75-81

School of Medicine, Division of Respiratory Cell and Molecular Biology, Southampton General Hospital, Southampton, United Kingdom.

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http://dx.doi.org/10.1067/mai.2002.120274DOI Listing
January 2002